LOCUS       NZ_CP102509            21312 bp    DNA     linear   CON 06-JAN-2024
DEFINITION  Streptomyces sp. NBC_00162 chromosome, complete genome.
ACCESSION   NZ_CP102509
VERSION     NZ_CP102509.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. NBC_00162
  ORGANISM  Streptomyces sp. NBC_00162
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8635149)
  AUTHORS   Nielsen,J.B., Gren,T., Mohite,O.S., Joergensen,T.S., Klitgaard,A.,
            Mourched,A.-S., Blin,K., Larsen,T.O., Weber,T., Gotfredsen,C.H. and
            Charusanti,P.
  TITLE     Identification of the biosynthetic gene cluster for pyracrimycin A
            and elucidation of a key reaction during its biosynthesis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8635149)
  AUTHORS   Joergensen,T.S., Gren,T., Blin,K. and Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2022) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 05-AUG-2022
            Assembly Method :: Flye v. 2.9-b1768; Polypolish v. 0.5.0; POLCA
            polisher from MaSuRCA v. 4.0.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 40.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina Nextseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/05/2024 18:03:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,275
            CDSs (total)                      :: 8,175
            Genes (coding)                    :: 7,805
            CDSs (with protein)               :: 7,805
            Genes (RNA)                       :: 100
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 371
            CDSs (without protein)            :: 370
            Pseudo Genes (ambiguous residues) :: 0 of 371
            Pseudo Genes (frameshifted)       :: 186 of 371
            Pseudo Genes (incomplete)         :: 231 of 371
            Pseudo Genes (internal stop)      :: 27 of 371
            Pseudo Genes (multiple problems)  :: 68 of 371
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:41:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1535258
            Orig. end                         :: 1556570
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102509.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Tilmann Weber, Dr.
            Professor, Novo Nordisk Foundation Center for Biosustainability,
            Kemitorvet, 220, 327D 2800 Kgs. Lyngby, Denmark.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21312
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="triceptide"
                     /region_number="12"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     triceptide_precursor) or triceptide_rSAM)"
                     /tool="antismash"
     cand_cluster    1..21312
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /kind="single"
                     /product="triceptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21312
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11312](+)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11312
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
     misc_feature    208..224
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.36"
                     /tool="antismash"
     misc_feature    953..972
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.34"
                     /tool="antismash"
     gene            1090..2484
                     /locus_tag="JIW86_RS07850"
                     /old_locus_tag="JIW86_07850"
     CDS             1090..2484
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037627.4"
                     /locus_tag="JIW86_RS07850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07850"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_257553123.1"
                     /transl_table=11
                     /translation="MPTPTRSRDQSPDQRPALDELIGLAGLLRAWRAAASAKMRRSKPL
                     SQAEVAARAGMTERWYGELERGASPRLRRPKIDQLAEALLLNEDQRETLYLYTDGGSPP
                     RSPKPPGYTDGLHPLQLLLDHQMPRPAYLSDAAWNIVGFNRAMAQWFPWVLEPGANLMR
                     WALLHPDAREQYVGWEEHARIYLAMVRMALVKHDRMPELVSVLNEVLADEDCRRIWDSK
                     PELVGHRDGHMFRLNISRFDHQDIEVVTQVLYPAAFPDLRFVAITWLGSREDPGAEAAR
                     RSPSAVEGSGGRVTPPRPAQGTPPRPYWALDSFEAARSLAGSSPVDLPALSAVAGRGTR
                     LTADFSGRNVIWATSEAGGTVAFEDLSTQEALARIPIPTLSAGARREYQNLLRSTLAPD
                     GPTAARQIDELLIPHRAAIDLLVDLGSQLSPAGAAAPSPGLSRSESGTGTERAQALAGR
                     LGAWPR"
     gene            complement(2408..3382)
                     /locus_tag="JIW86_RS07855"
                     /old_locus_tag="JIW86_07855"
     CDS             complement(2408..3382)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955393.1"
                     /locus_tag="JIW86_RS07855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07855"
                     /product="GlxA family transcriptional regulator"
                     /protein_id="WP_257553124.1"
                     /transl_table=11
                     /translation="MRSRTVLVTLYDGVEALDVTGPVGVLAGANAYLAATAPGQTGYRI
                     ATASPGGSAVASLSGVTLMPDVDLADAEVPHTLLVPGGAGGVPDAGAGHPDVVSWLKEN
                     APKAERVVSVCTGAFLLAEADLLAGRRVTTHWDKAGELAQRYPDVAVEPDSIFIRDGSV
                     YTSAGVTAGIDLALALVEEDIGRDAALTIARYMVVFLRRSGGQGQFSTQMQAQLAHRQE
                     LRELQQWIADHPDADLSVDALAQRANLSARQFTRTFAEETGVTPGRYVANTRLETARRL
                     LEDTDDDVVRIAALSGYATTEAMRRAFQRVLGLSPSQYRTRCG"
     gene            complement(3497..3949)
                     /locus_tag="JIW86_RS07860"
                     /old_locus_tag="JIW86_07860"
     CDS             complement(3497..3949)
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010472089.1"
                     /locus_tag="JIW86_RS07860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07860"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_257553125.1"
                     /transl_table=11
                     /translation="MVPEDASPRSGPDDHRLRVAAAVVVHEGRVLLVRRRMAEGNLSWQ
                     FPAGKVEPGETWEDAAVRETKEETGLDVSAAGALGERVHPMTGRLMSYAACDAVRGSAR
                     AAAPTEIAEVAWVTLAELPGYIPGGIFEPVQRYLEALIGLPPPGQS"
     gene            complement(3939..4487)
                     /locus_tag="JIW86_RS07865"
                     /old_locus_tag="JIW86_07865"
     CDS             complement(3939..4487)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020120654.1"
                     /locus_tag="JIW86_RS07865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07865"
                     /product="flavoprotein"
                     /protein_id="WP_257553126.1"
                     /sec_met_domain="Flavoprotein (E-value: 6.9e-10, bitscore:
                     37.8, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEPQRRPFLYVVVCAAGIADDVGKLITAAQERNWDVGVVATPHA
                     LPFLDVPDIETQTGFQIRSAWRQPGDDRPLPPADAIAVAPATFNTVNKWAAGFADNLAL
                     AILCEAYGMDIPTAVLPYVNSALAAHPAYRRSISELREMGISIGSYEPHRPKAGGGADR
                     FHWEEAIHLLAPHMRNHGA"
     gene            complement(4499..4963)
                     /locus_tag="JIW86_RS07870"
                     /old_locus_tag="JIW86_07870"
     CDS             complement(4499..4963)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662460.1"
                     /locus_tag="JIW86_RS07870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07870"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_257553127.1"
                     /transl_table=11
                     /translation="MAQSLEITPIGTVIGGRVEPTDDHWGGPAIIRLNPDFPVEVVQGL
                     EEFSHLLVVWQFHKASPEDVDLHARSPRNNPAWQPSGTFVHRNHRRPNQLAQSFPRLVK
                     VDGLDLHVADLDAIDGTPVYDVAPYFQEMGPRGEVREPSWPAEMLADYWR"
     misc_feature    complement(5022..5035)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            5138..6007
                     /locus_tag="JIW86_RS07875"
                     /old_locus_tag="JIW86_07875"
     CDS             5138..6007
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007264926.1"
                     /locus_tag="JIW86_RS07875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07875"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_257553128.1"
                     /transl_table=11
                     /translation="MNGSLPAAAQVDLRRQPVDDVLERVEQALHVRLDRQALLRKRRSL
                     GGRTERGTWVRIERRGFERIGAQGWNGTEAAAVLQGVAMPEWFQGVAWREQGEPVMWRA
                     DELELMTSPSVGKSALVLDDPGLPDTWWEALNASLDALAAQRTPRIATPDTVTITQEQV
                     TQTLGEAFPGLSDTRIERWAPAHADLTWANVMGPEFSVIDWEDWGMAPRGLDAATLWGN
                     ALAVPALAGRVRHERRADFESRDGKLMSLFFLSKTLGSLSYEGDPLLAPARKEAKRLVD
                     ELQSTPDK"
     gene            6135..6578
                     /locus_tag="JIW86_RS07880"
                     /old_locus_tag="JIW86_07880"
     CDS             6135..6578
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036859.1"
                     /locus_tag="JIW86_RS07880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07880"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_257553129.1"
                     /transl_table=11
                     /translation="MPEKVTKEKVLVYVVRDGRLLVFRHTDYSYEEVGIQVPAGSIRPS
                     ETPEAAALREAREETGLSDFKIVRKLGETEYDISPYRCEIQHRHVFHLELTEPTPERWM
                     SQEDHDGEQEPTYFECFWIPLEAAHILQSGQGALLGRLSDSPL"
     gene            complement(6774..7211)
                     /locus_tag="JIW86_RS07885"
                     /old_locus_tag="JIW86_07885"
     CDS             complement(6774..7211)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007265072.1"
                     /locus_tag="JIW86_RS07885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07885"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_257553130.1"
                     /transl_table=11
                     /translation="MIERVRAVLVTADDTMLVIRRTKPDIPVYWVLPGGGVEPSDESRE
                     AALHREIHEEIAGKADIVRLLHTMESDDERQLFYLARIATWSFEDRTGPEFSAEGRGEY
                     ALEEIPLTVEGIDGIDLKPEEIAHVLRGAIGSGTVRAGAAK"
     gene            complement(7242..7901)
                     /locus_tag="JIW86_RS07890"
                     /old_locus_tag="JIW86_07890"
     CDS             complement(7242..7901)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019355690.1"
                     /locus_tag="JIW86_RS07890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07890"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_257553131.1"
                     /transl_table=11
                     /translation="MGLGQGISTYAHALLAAFEPDGSPGIAANADLTDPGAVQTMVELV
                     RAEIGPIDILVNNAGSYPRVPWKDTDEAAWSYSLDVNLTAHYRTCHAVTPGMIERRWGR
                     IVNIGSVNARVGRTNLVAYSTAKAGLLGLTRSLARELGPYGVCVNTVMPGAIQVEAENA
                     IPAQHLARPEDQIKRQCVPRRGRPEDVAALVAFLVGSSASFITGQSVHVDGGRLLH"
     gene            7960..9201
                     /locus_tag="JIW86_RS07895"
                     /old_locus_tag="JIW86_07895"
     CDS             7960..9201
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008739359.1"
                     /locus_tag="JIW86_RS07895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07895"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_257553132.1"
                     /transl_table=11
                     /translation="MGVSGYIEEQERIGQRVRRQRLSVGMTQADLAAALGRTQGWVSKL
                     EKGRIELDRAGLINAVAAALHCHPNTLIERPYSGGGAETKWQVSAASIIRELRRYDLAP
                     VFDGTPRPSEVLWHDMKRLLRLRDAAANAAVLKELPDMLREARALAEASTGHEREEAFA
                     IYAVACKFAHTAAHALGHPELVAMACERATWSAQLSGDPVMPAMALWMRMWDTWASADW
                     DDALALGDKALASIEAEYEAGDPLALRMWGALHLRAAISSARGGNAAGSDERLALARTA
                     GERVNSYVGPEIHDRHSVTFSLGNVVIHGVSAALEMSDQTKALRLNREADPAHIAVLPN
                     SRLGHHHMDLARAWLWDGNRDQALTELETAERIAPQLVRNHPVARATLRKIIYAERAAT
                     RQRLRGMTGRFSLD"
     gene            9260..9664
                     /locus_tag="JIW86_RS07900"
                     /old_locus_tag="JIW86_07900"
     CDS             9260..9664
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JIW86_RS07900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JIW86_07900"
                     /product="hypothetical protein"
                     /protein_id="WP_257553133.1"
                     /transl_table=11
                     /translation="MTSTRRTDHDRVRQQADDPEPRWPLRGDLAHDTATSRTGVVIDVP
                     GDTGTTVYRLCPEGGGEDGWNASLNTLVPAEDAPVPLPRRAPGGRMQHEPEYAPWDDPF
                     GSPDPSPSLRVRAERGMERFRKSAGTDGAA"
     gene            9661..9870
                     /locus_tag="JIW86_RS07905"
                     /old_locus_tag="JIW86_07905"
     CDS             9661..9870
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008739357.1"
                     /locus_tag="JIW86_RS07905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07905"
                     /product="hypothetical protein"
                     /protein_id="WP_053173540.1"
                     /transl_table=11
                     /translation="MSGRPSWLYEGARVLDPAEDREGIVQFIGDWEDPKTRRFIPEAVF
                     LRPEGGGVEWVVADHQALRQADPR"
     gene            10001..11074
                     /gene="amcB"
                     /locus_tag="JIW86_RS07910"
                     /old_locus_tag="JIW86_07910"
     CDS             10001..11074
                     /codon_start=1
                     /gene="amcB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_rSAM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041718.1"
                     /locus_tag="JIW86_RS07910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07910"
                     /product="cyclophane-forming radical SAM peptide maturase
                     AmcB"
                     /protein_id="WP_257553134.1"
                     /sec_met_domain="PTHR43273 (E-value: 6.1e-44, bitscore:
                     149.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 5.2e-12, bitscore: 45.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="triceptide_rSAM (E-value: 1.0, bitscore:
                     1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQPTTKCLPMDCTYCYLPFRKMNHLMPVTVAEAVAASVNPWAAHD
                     PAFEVVWHGGEPLATGREHLAALMSPFEGVKHSIQTNAALVDDAWCEFLLEHEVHVGVS
                     IDGPEDMNTHRVTLAGHPGFRVTMRGIERLRRHGIPFSAIAVVSDPAPENAARFYDFFA
                     ELGVTTLGVNVEEEEGVNRGAKESDPVRTTEFWAALADAWRANPVIRLREIQRVLNFAG
                     AVLGSHDTAPTPTSAPWDPMPTVAYDGGVIMLSPELAGFTDARFGDFTTGNVLKDGLDV
                     LVAEAEERTPWITEFWQGVDACRDTCPAFAFCGGAHAANRYFEHAGRFDGTRTRYCTTA
                     KIALLEGVTRHVHSHAH"
     gene            11052..11312
                     /gene="amcA"
                     /locus_tag="JIW86_RS07915"
                     /old_locus_tag="JIW86_07915"
     CDS             11052..11312
                     /codon_start=1
                     /gene="amcA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_precursor"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041721.1"
                     /locus_tag="JIW86_RS07915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07915"
                     /product="multiple cyclophane-containing RiPP AmcA"
                     /protein_id="WP_257553135.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIHTPTDAATLVMDSAEGFESLLEAAGTGAVARWENSWTNATWS
                     NQPTSEAAHAKPVAAFDNRPTWDNPTATFDNRPTWDNWKNK"
     gene            11377..12051
                     /locus_tag="JIW86_RS07920"
                     /old_locus_tag="JIW86_07920"
     CDS             11377..12051
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024986.4"
                     /locus_tag="JIW86_RS07920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07920"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_257553136.1"
                     /transl_table=11
                     /translation="MAIRTFGHATITLPELDEPGLYLSNVDSLDSSRGTVQDFVYGDAD
                     LRSLDLTDTQLVTGRLSGIRAKRLEFEAVNLHGVEISDSDLGTARWTESKLTRVHFRDC
                     KLMGAALDGLVLDDVLFESCKLDFATFEKVRATGPVAFIGCVLTEATFADCDLSDTVFT
                     DCTLRRAEFGTGRYRNTDLRENDLSAIRGVANLAKVRIDPGQQSDLAEALVNELNITIG
                     DD"
     gene            12069..12788
                     /locus_tag="JIW86_RS07925"
                     /old_locus_tag="JIW86_07925"
     CDS             12069..12788
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JIW86_RS07925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JIW86_07925"
                     /product="hypothetical protein"
                     /protein_id="WP_257553137.1"
                     /transl_table=11
                     /translation="MPLHIAYGDPSALRARCEIATVRTTRPEETAYEPGAIIPAGQWRP
                     MTKVDVKAVSAPRRPLDSTLVEIVRPTYQVGLLLEDLTGPLGDPDAVYLGQALAKPGMT
                     TTTDNYEDGRLIGLHLDNWDKLQYTDKHTGRRRLCLNLGPGTRYIIFGTIDAQAVCRAV
                     HPNDHADRFPHTQDYRDYVASGRPIRIIRTRLAPGEGYVAPTEYLLHDGSTEAQDRPSA
                     AAFWLGQWPRGILPSLT"
     gene            complement(13431..15335)
                     /locus_tag="JIW86_RS07930"
                     /old_locus_tag="JIW86_07930"
     CDS             complement(13431..15335)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012789.4"
                     /locus_tag="JIW86_RS07930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07930"
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="WP_257553138.1"
                     /transl_table=11
                     /translation="MTIPYEQAAFAKDRIEALASAMGLTLPHEEQWDFLQSMISLDLQA
                     APGSGKTSLIGLKLALLAAGWSSRTRGICVLSHTNTAKTEITARLAATPAGRRLLAYPH
                     FIGTIQSFANTFLALPAVRALGVEIQAVDDEAYAAAALRLLERDPRFRTLLGTLDRQRD
                     GRQLAATARFVCEARDLAVVATRSLPFSKETSSGKQFILLKRDLSRRGIFRYEDMFAIA
                     EQHLVRNPDLADATSRRFPFVLLDEMQDTSLVQERLLDKVFGSTGTVVQRVGDVNQRIF
                     NDGQPGRTEAGTFPLPMAAELPVSRRFGSRIAGLASELTVHRRQRIHGAGPEGAIVLLT
                     YDESTVAQVVPAFERLAATLVPPPLLQQSPPRVLGARRHRGSSPNFPQSLACYVPELLA
                     QADAVRGSLIRTTRSAQTQWQSDDSHGAVSHVWNAVRGLVRPMTEGYLPAIGRLEREAV
                     TAGGKARAVLLSMLTAQLDDEGLWESLTDQLMRVLSELTSVTEADLNRMGEVFLYVPRG
                     QSPRTLLPTSDETDLVPSIASTIQRAKGETHSATLLLDCLDKTGKKFDVNEVLNLLASG
                     RDLDRATSTVKRAAQLIFVGATRPTHLLAFATPRQRAEPYAEALVARGWSVHDASATL"
     gene            complement(15332..17206)
                     /locus_tag="JIW86_RS07935"
                     /old_locus_tag="JIW86_07935"
     CDS             complement(15332..17206)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024867.4"
                     /locus_tag="JIW86_RS07935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07935"
                     /product="AAA family ATPase"
                     /protein_id="WP_257553139.1"
                     /transl_table=11
                     /translation="MYLAHLRAENFRIFGPAGQEGGDADRSLRVDFAPGTTVLVGENDS
                     GKTAIVDAIRVCLLTTAADYYRVTKDDFHVGAGGRSDTFTITCGFRGLSAEEKGTFLEL
                     LTTDASGSALYVTFRAQLMDPQRSNRVSVTTRTGPDGKGPALDGAARELLKATYLRPLR
                     DAEAELRSGRGSRLSQILASYPAILKEEQDDFNAETDTADTLVGILRRAEHHITSNAAV
                     AAARDDINTNYLEKFSIGSDVLRGEIGVAGDATLARALERLELTLFAGTGEWTRRGLGY
                     NNALFMAAELLLLGNSETAPLLLIEEPEAHLHPQLQTRVMDLLYERAAGTAGAAAGVQV
                     ILTTHSPNLASAVPVEWLTLVARGSTFSLAPGHTRLDAGDYAFLSRFLDVTKANLFFAR
                     SVAVVEGDAEALLLPALAQAVGRSFNESGVSVVNVGHTGLFRYSRIFQREGRQIPVTVA
                     CIRDRDLLPDGTPTDMRGELPCVSDMTAEQIAAHVDALTRGDDGNVKTFVSDHWTLEYD
                     LAAASWTMARVMHQAVRAARASERSWPDAERLAELDGEAAQEVEEWRAAGVNRPEAALR
                     IYRPLKKGNASKAIAAQHAARLLKSTPLTEAHIPAYLRRAFAHLCGEP"
     misc_feature    17317..17331
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.71"
                     /tool="antismash"
     gene            complement(17381..19138)
                     /locus_tag="JIW86_RS07940"
                     /old_locus_tag="JIW86_07940"
     CDS             complement(17381..19138)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016362.4"
                     /locus_tag="JIW86_RS07940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07940"
                     /product="restriction endonuclease"
                     /protein_id="WP_257553140.1"
                     /transl_table=11
                     /translation="MDGLLGHGAAGSTERSRQSSSRPAWTQRALAGVPVIEWVGKRIAR
                     PWVGEVLSGPACRDLGVAVAGGGDEYARERARQAKERERRQKAAETEAKRKARDEKVAY
                     EAARAQEAVDKTSVTEHDVEQLAGLLRAAVLEGRPLSFDSLRQHFVPAVFAPSKSRTKP
                     VPLPRWGEYEPEPPRGWLGALGFGRRSYDAEVEAARKRFDEALRDHAREEHKRVGKLDA
                     AQARHDERNQQEAARIEEWNAGIEARRVAYQERDVEAVEWFIDQVLAASTYPHGFPKAH
                     QVSYQADTGDLLVEIDLPLEDVVPAARAYRYVKTRDEITLVPRPEKERHELYASVLAQT
                     ALRTVHELFAADTDGVVRSVALNGHVATIDRATGREVHPCLITLQAGRQEFSELVLTQV
                     DPQACLKRLRSLISPNPYQLEPVRALVTFDLSKYRLMDSMDVVAGLDSRPVLMDLSPTE
                     FEHLVRQLFEAIGLDSVNTRPSQDEGVDAVAMNTDPVMRGLCIIQAKRTAKVVPFESVS
                     ALAGVVEHKRAAKGILVTTSWFGRASEAFANDHGRLELLDGANLVHLFKEHLDLDVIPG
                     PVPPKRRPR"
     misc_feature    complement(18749..18751)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19379..20343)
                     /locus_tag="JIW86_RS07945"
                     /old_locus_tag="JIW86_07945"
                     /pseudo=""
     CDS             complement(19379..20343)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1208: pirin
                     domain-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059009.1"
                     /locus_tag="JIW86_RS07945"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07945"
                     /product="pirin family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSNLDRQPALSVCGGRGFVVAEPVRELLSPRTVKLGESTEVRRLL
                     PNLGRRMVGAWCFVDHYGPDDIADEPGMQVAPHPHSGLQTVSWLHEGEVLHRDSVGSLA
                     TIRPRELGLMTSGRGISHSEESPRPHARFLHGAQLWVALPDAHRDVEPHFQHHAELPRV
                     TSPGLTATVILGTLDTATSPGTAYSPIVGADLSLAAGTETRLPLDPDFEYAVLSMSGEA
                     HVDDVPVLPGSMLYLGCGRTELPCGQPRTRA"
     misc_feature    complement(19402..19404)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(20329..20343)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     gene            20456..20800
                     /locus_tag="JIW86_RS07950"
                     /old_locus_tag="JIW86_07950"
     CDS             20456..20800
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947243.1"
                     /locus_tag="JIW86_RS07950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07950"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_215140118.1"
                     /transl_table=11
                     /translation="MSTPYFEHGTAAERWARARLFFDAKEYATAARILDTLAGEAPEQL
                     APRLLLARAYYHSAQLSRAERELRAILERWPVEDYAQLMLGRTLERSGRAAEARPYLRM
                     AAAMAGEFPE"
ORIGIN
        1 ccgcaccgcc tacgacccca aggcgctggc agccctcgac cagtggtcgg ccaccggacg
       61 accgcaggcc gacccggctg ccgccggccc cgtcgtcctg gtcgagaagg cggaccggat
      121 cgagaccgac tcggcccacc acgccacctt ctggatcgag aactggcccc ggatcgaaac
      181 ctctcccggc ttcctgcacc agcttctctt cacctctggg gtacggcgca ccctgtccct
      241 gacctacgag cccaaggggc tggacgccgc gctcaaggac gtgcagcgca ggaaggccac
      301 cgtgatcgcg gacgccgccg agcgccagcg caagggccag gtcgactccg aagaggactc
      361 ggtggagtac gcggacatca aggaccgcga acgccagctc atcgccggcc acgccgacgt
      421 cgccccccga ctacccctgg ctccgccaac accccggctc gggcgacgta ctgctccgtc
      481 ctacgtcgcg ccgaggtgag tggggtgagt gactcgatcg cgcagagcat cccgttcgca
      541 tcgtggagca gccgagccag aatctgccgt tggggtgctt cactgaaccg atacgccgcc
      601 gctcgcatcc cgaggctgac ggcgcccgaa ccgaggcggt attttccggc ctcatccctc
      661 acgaacacgt cgtaggccag ccccgaattg agtattcggt gcaccgtgct cttgttgaga
      721 cccgcttctc tggcaatggc gcgcggccca tgggacgggc catccatgga cgccagggtt
      781 cgctgcacgt ggaatacgcg gtcacacgcc gtgcctgcca tatccccctc ctattccgtc
      841 atccaccggg tggggcgcgt aggtgcagac ccggcgggta tcaatcgggc gctacgccgt
      901 ctttccaagc gtcccagccg tcgaaaggaa ctctgcttcc ggaagtgcga cttccgggac
      961 taaagtccct acggttgcgg cgccgaggac cgccccgtcc gaaaccccac agggcttgtc
     1021 cccattgggc cgacgaccga gagggtcact tcacgcgagg acggcatcac cgggagcgag
     1081 ggaggaatca tgcctacgcc cacccgaagt cgggaccaaa gtcccgacca gcggcctgcc
     1141 ctggatgagc tgatcgggct tgccggactg ttgcgagcgt ggcgcgcagc agccagcgcc
     1201 aaaatgcggc ggagcaaacc gctgtcgcaa gccgaggtgg cagcccgggc cgggatgacc
     1261 gagcgttggt acggggaact ggagcgagga gcgtctcccc gcctgagacg cccgaagatc
     1321 gaccagttgg cagaggcgct gctgctgaac gaggaccagc gcgagaccct ctacctctac
     1381 acggacggag gctccccgcc ccgctccccc aagcctccgg ggtacaccga cggccttcac
     1441 ccgctacaac tgcttctcga ccatcagatg ccacggcccg cgtacctcag cgatgccgcc
     1501 tggaacatcg tcggattcaa ccgggccatg gcccagtggt tcccctgggt cctggagccg
     1561 ggcgccaacc tgatgcgttg ggcactgctg catcccgatg cccgggagca gtacgtcgga
     1621 tgggaggagc acgcacggat ctacctcgcc atggtgagga tggcactggt caaacacgac
     1681 cggatgcccg agctggtctc ggtgctgaac gaggtcctgg ccgacgaaga ttgtcgccgc
     1741 atctgggaca gcaagccgga gttggtgggc caccgggacg gccacatgtt caggctgaac
     1801 atctcccgtt tcgaccacca ggacatcgag gtcgttactc aggtgctcta ccccgccgcc
     1861 ttcccggacc tccgcttcgt tgccatcacc tggctcggca gccgagaaga ccctggcgcc
     1921 gaagccgccc gccggagtcc atctgcggtc gagggcagcg gaggccgcgt cacacctcca
     1981 cggccggccc aggggacacc cccgcgccca tactgggccc tcgactcctt cgaagcggca
     2041 cgctcgctcg ccggctcctc ccccgttgat ctaccggccc tcagcgcggt ggccggtcga
     2101 ggtacccggc tcacagcgga cttctcgggt cgcaacgtca tctgggcgac gagcgaggca
     2161 ggcggcacgg tcgccttcga ggacctcagc acgcaagaag ccctcgcacg catcccgatt
     2221 ccgacactca gtgcgggagc tcgacgggag tatcagaacc tgctccggtc cactctggcc
     2281 cccgatggcc cgaccgctgc gaggcagata gacgagctcc tcatccctca ccgcgcagcc
     2341 atcgatctct tggtggacct tggcagccag ctcagccccg ccggcgcagc cgccccatct
     2401 cccggcctca gccgcagcga gtccggtact gggacggaga gagcccaagc actcgctgga
     2461 aggctcggcg catggcctcg gtagtggcgt aaccgctcaa ggcagcgatg cgcacgacat
     2521 cgtcgtcggt gtcctcgagc agccgcctcg ctgtctcgag ccgggtgttg gccacatagc
     2581 gcccgggggt gacgcccgtc tcctcggcga acgtccgcgt gaactgccga gccgacagat
     2641 tggcgcgctg agccaaggcg tcgaccgaca ggtcggcgtc cgggtggtcg gcgatccact
     2701 gctggagctc acggagttct tggcgatgcg cgagctgcgc ctgcatctgg gtgctgaact
     2761 ggccttggcc gccggacctc cgcaggaaga cgaccatgta gcgcgcgatc gtcagggccg
     2821 cgtccctccc gatgtcctcc tccaccaggg caagagcgag gtcgatgccg gccgtgacgc
     2881 ccgccgaggt gtacaccgag ccgtcccgga tgaagatcga gtccggttcg actgcgacgt
     2941 cgggataccg ctgcgccagc tccccagctt tgtcccaatg tgttgtcacc cgccgacctg
     3001 cgagcagatc ggcctcggcg agcaggaacg cacccgtaca cacggagacg actcgctccg
     3061 ccttcggggc gttctccttc agccacgaaa cgacgtccgg atgaccggca cccgcgtcgg
     3121 gaacgcctcc ggcaccgccc ggcacgagca gcgtgtgggg aacctcagcg tccgccaggt
     3181 ccacatcagg catcagggtc accccgctga gcgatgccac ggctgacccg cccggggatg
     3241 ccgtagcgat gcggtacccg gtctgccccg gagctgtggc ggcgaggtaa gcgttggccc
     3301 cggccagtac gcccacgggg ccggtgacgt ccagcgcctc aacgccgtca tagagcgtga
     3361 ccagcaccgt gcgggacctc atacctcaac catgcccacc ctcaaaggtg cccgcaatgc
     3421 aagactccgg catgtacggc aacgtggatc ccggacgggc tccagccgat cccctcggcc
     3481 ccgtggctcc gcggcatcag ctctggccag gcggcggtag cccgatcagg gcttccaagt
     3541 acctctgcac cggctcgaag atcccgcccg ggatataccc gggaagctct gcaagggtca
     3601 cccaggccac ctcggcgatc tcggtcgggg cggcggcacg tgcggaaccc ctcacggcat
     3661 cgcaggcggc gtacgacatc agccttccgg tcatcggatg aacccgctcg cccagcgccc
     3721 cggccgcgga tacgtccaga ccggtctcct ccttcgtctc ccgtacggcc gcgtcctccc
     3781 atgtttcccc gggttcgacc ttgcccgccg ggaactgcca cgagaggttc ccctccgcca
     3841 tccgacgtcg caccaacagg acccggccct catggaccac gacggcggcg gcaaccctca
     3901 gtcggtgatc gtccggcccg ctgcggggcg aggcgtcctc aggcaccatg gttccgcatg
     3961 tgcggtgcca gcaggtggat cgcttcctcc cagtggaagc gatcggcgcc gccgcctgcc
     4021 ttcggacggt gaggctcgta gctgccgatc gatatcccca tctcacgaag ttcagaaatg
     4081 cttcgccggt aagcggggtg cgccgccagg gcggagttca cgtacggcag gactgcggtg
     4141 gggatgtcca tgccgtacgc ctcgcagagg atggccagcg cgaggttgtc ggcgaagccc
     4201 gccgcccact tgttgaccgt gttgaaggtc gctggagcga ccgcgatggc gtctgccggc
     4261 ggcagggggc gatcgtcacc cggctgcctc caggcggaac ggatctggaa gcctgtctgc
     4321 gtctcgatgt cagggacgtc gaggaagggc agggcatgcg gagtggcgac gaccccgacg
     4381 tcccagttcc gctcctgtgc cgccgtgatc agcttgccga cgtcgtccgc gatcccggcg
     4441 gcacagacga cgacgtacag gaacggcctg cgctgaggct ccgtcacgtg agaccccttc
     4501 agcgccagta gtccgcgagc atctccgccg gccagctcgg ttcccggacc tcgccccgcg
     4561 gacccatctc ctgaaagtag ggcgcgacgt catagaccgg ggtgccgtct atcgcgtcga
     4621 ggtcggcgac atgcaggtcc aagccgtcga ccttcaccaa gcgtggaaag gactgggcca
     4681 gctggttcgg ccgtcgatgg ttccggtgga cgaacgtgcc ggagggctgc caggcgggat
     4741 tgttgcgagg gctccgcgca tggaggtcga cgtcttcggg cgaggccttg tggaattgcc
     4801 agacgacgag gaggtgggag aactcttcga gaccttggac gacctcgacc gggaagtccg
     4861 ggttcaagcg gatgatcgcg gggcctcccc agtggtcatc agtgggttca acccgtcccc
     4921 cgatcaccgt tccgataggc gtgatctcca gcgactgcgc catgcgctcc ccctcaagcc
     4981 tcgtcgtcac cggctcaatc tacagcggat gatgtggccc cttgagctcc gacaaccgcc
     5041 agagatgaca aggaagttga gatgctccgt gttgacggac ggctcgtgtc agtgggcccg
     5101 ctcctgctag ggtcccccgt tcgcaaagga ggtcgtgatg aacggatccc tgcccgctgc
     5161 cgcccaggtg gacctgcgcc ggcagccggt agacgacgtg ctggagcgcg tggagcaggc
     5221 cctgcacgta cggctggacc ggcaggcact gcttcgcaag cgccgctcct tgggcggccg
     5281 tacggagcgg ggcacctggg tgcgtatcga gcggcgggga ttcgaacgga tcggcgcgca
     5341 aggctggaac gggaccgagg ctgccgccgt gctgcagggg gttgcgatgc ccgagtggtt
     5401 ccaaggcgtg gcatggcgcg aacagggcga gccggtcatg tggcgtgcgg atgagctgga
     5461 gttgatgaca tcgccatctg tcggaaagag cgccctggtg ctcgatgacc cgggccttcc
     5521 tgacacatgg tgggaggcgc tgaatgcttc tctggacgcg cttgccgcac agcggacgcc
     5581 gcggatcgcg accccggaca cggtgacgat cacgcaggag caggtgacgc agaccctggg
     5641 ggaagctttc cccggcctct ccgacacgcg gatcgagcgg tgggctcctg ctcatgcgga
     5701 cctgacctgg gccaacgtga tgggaccgga gttctccgtc atcgactggg aggactgggg
     5761 catggcaccc cgaggcctgg acgccgcaac gctatggggc aacgcgcttg ccgtcccggc
     5821 gctcgcgggc cgcgtccggc atgagcgacg cgcggacttc gagagccggg acggcaagct
     5881 gatgtcgctc ttctttctct cgaagaccct cggctccctc tcctacgagg gagatccgct
     5941 gctggcgccg gcccgaaagg aagccaagcg cttggtggac gagcttcagt ccaccccgga
     6001 caagtgaaga tcagccgtac gcctgcgccg gtccgcggac agccgaaatg atcaccgacc
     6061 acgggatagc cagtcccggc ctccaccggg cctggcccac gaatcagttc ctgaaccaag
     6121 tggaggttgg cgccatgccc gagaaggtca cgaaggagaa ggtcctcgtc tacgtcgtcc
     6181 gtgacggacg cctgctcgtg ttccgccaca ccgactactc ctatgaggag gtcggcatcc
     6241 aggtgcccgc aggcagcatc cgccccagtg agaccccgga agctgccgcc ctgcgcgagg
     6301 cccgcgaaga gacgggcctg tcggacttca agatcgtccg caagctcggc gagaccgagt
     6361 acgacatcag cccgtaccgg tgcgagatcc agcaccggca cgtcttccac ctggagctga
     6421 ccgaaccgac gccggagcgc tggatgagcc aggaggacca cgacggcgag caggagccga
     6481 cctacttcga gtgcttctgg atcccgctgg aggccgcaca cattctccag tccggccaag
     6541 gcgcgctgct ggggcgcctg tccgactcgc cgctataagc gggggcgcgg aggttcattg
     6601 gcagcgcttt gagatccctg gccaacgccc gccgtctggc ccgtaccacc ccactgcgtc
     6661 cgtcccaacc cgagcagctc acagcaacca acagccgccg cactccgtag gcgccgtcag
     6721 gcccgatgca cttcggcgtc ggtccccgac ggcaagtcca cacaaccgga cggctacttc
     6781 gcagcccctg cccgaacggt gccggagccg atagcacccc ggaggacgtg ggcgatctcc
     6841 tcgggtttga ggtcgatgcc gtcgatcccc tccacggtca gcgggatctc ctccagcgca
     6901 tactcaccac ggccttctgc actgaactcg ggcccggtgc gatcctcgaa ggaccaggtg
     6961 gcgatgcggg cgaggtagaa gagctgacgt tcgtcgtcgg actccatcgt gtggaggagc
     7021 cggacgatgt cggccttccc cgcgatctcc tcgtggatct cccggtggag agcggcctcc
     7081 cgcgactcat cgctgggttc gacgccgccg ccgggcagta cccagtacac ggggatgtcg
     7141 ggcttggttc ggcggatgac cagcatcgtg tcgtcagcgg tgacgaggac ggctcggact
     7201 cgttcgatca tgtcggtctg tctccttgct tgttgacggt ctcagtgcag cagccggcca
     7261 ccgtcgacgt ggacggattg cccagtgatg aacgatgcgg aggagcccac gaggaacgcc
     7321 accagggctg caacatcttc gggtcgaccg cggcgaggga cgcactggcg cttgatctgg
     7381 tcctccgggc gcgcgaggtg ctgggcgggg atggcgttct cggcctcaac ctggatggcg
     7441 ccgggcatga ccgtgttgac gcagaccccg tacgggccca gttcgcgggc gagggagcgg
     7501 gtcagtccca gtagcccggc cttcgcggtg ctgtacgcga ccaggttcgt ccggccgacg
     7561 cgggcgttga cgctgccgat gttcacgatc cgcccccagc ggcgttcgat catgccgggg
     7621 gtcaccgcgt ggcaggtgcg gtagtgggcg gtgaggttca cgtcgaggga gtagctccag
     7681 gctgcctcgt cggtgtcctt ccaggggacg cgggggtagg agccggcgtt gttcacgagg
     7741 atgtcgatgg ggccgatctc ggcgcggacg agctcgacca tggtctggac ggcgccgggg
     7801 tcggtgaggt cggcgttcgc cgcgatcccg gggctgccgt ctggctcgaa ggcggcgagg
     7861 agggcatggg catatgttga gatcccttgg ccaaggccca ccttctggag cgccccagcg
     7921 gtaccttcgc gtcagaagaa gcggtcgcag atcggggtga tgggtgtgag cgggtacatc
     7981 gaggagcaag agcggatcgg acaacgggtc cggcgtcagc ggctctcggt tgggatgact
     8041 caggccgacc ttgccgccgc actggggcgg acgcaggggt gggtatcgaa gctggagaag
     8101 gggcggatcg agctggaccg ggccggtctg atcaacgccg tggccgccgc gctccactgc
     8161 catccgaaca ccttgatcga gcgcccgtac tcgggcggcg gcgccgaaac caagtggcag
     8221 gtctcagcgg cctccatcat ccgggaactg cgccggtacg acctggctcc cgtctttgac
     8281 ggcacccctc ggccgtccga ggtgctgtgg cacgacatga agcgcctgct ccgcctgcgc
     8341 gacgccgcgg cgaacgccgc cgtactgaag gagctgccgg acatgctgcg cgaggcccgg
     8401 gccctcgctg aggcgtccac tggccacgaa cgtgaagagg cgttcgcgat ctatgcggtg
     8461 gcctgcaagt tcgcccacac agcggcccat gccctcggac atcccgagct ggtcgccatg
     8521 gcctgcgaac gggccacctg gtccgcgcag ctctcaggtg acccggtgat gccggcgatg
     8581 gcgctgtgga tgcgcatgtg ggacacgtgg gcgtcggccg actgggatga cgccctcgcc
     8641 ctcggggaca aggccctcgc cagcatcgaa gccgagtacg aggccggcga ccctctcgcc
     8701 ctgcgtatgt ggggcgccct gcacctgcgg gccgcgatct cgtccgcgcg cggcgggaac
     8761 gctgctgggt cggatgagcg gctcgcgctt gcccgtacgg cgggcgagcg ggtcaactca
     8821 tacgtcgggc ccgagatcca cgaccggcac tcggtcacgt tcagcctcgg aaacgtcgtc
     8881 atccacggcg tcagcgccgc cttggagatg agtgaccaga cgaaggcgct ccggctcaac
     8941 cgcgaggcgg accccgcgca catcgcggtt ctgccgaact cccggctcgg tcaccaccac
     9001 atggaccttg cccgcgcgtg gctgtgggac ggtaaccgcg accaggccct gaccgaactg
     9061 gagaccgccg aacgtatcgc tccccaactg gtgcgcaatc accctgtcgc tcgcgctact
     9121 ctgcggaaga tcatctacgc ggagcgggct gctacgcgcc agcggctgcg cggcatgacc
     9181 ggacgttttt cgctggactg acctggggac attccccgga ttcatattgc cccgtagcgg
     9241 agcgcatacg ttccgctaca tgacctcgac gcgtcgcact gaccatgacc gcgtacgaca
     9301 gcaggcggac gaccctgaac cccgctggcc gctgcgcggc gaccttgcgc acgacaccgc
     9361 aacctcccgc acgggtgtgg tcatagacgt ccccggggac accggcacca cggtctaccg
     9421 cctgtgtccc gagggcggcg gcgaggacgg ctggaacgcc tcgctcaaca ccctcgtgcc
     9481 cgcggaggac gcccccgttc cgctcccccg cagggccccc ggcggcagga tgcagcacga
     9541 gcccgaatac gccccgtggg acgacccgtt cggcagtccg gaccccagtc cctccctgag
     9601 ggtccgcgcc gagcgcggca tggagcgatt caggaagtcg gcgggcacgg acggtgcggc
     9661 atgagcgggc ggccctcctg gctctacgag ggcgcccgcg tactggaccc cgccgaagac
     9721 cgcgagggga tcgtccagtt catcggcgac tgggaagacc ccaagacccg ccgcttcatc
     9781 cccgaagccg tcttcctgcg ccccgagggc ggcggcgtcg aatgggtcgt cgccgaccac
     9841 caggccctgc gccaggccga cccccgctga ccccacccac gctccgcccg gtgcctccaa
     9901 cagcaccact agccgaggcg ggacaccccg cccggaccca atcgagagga gcacgatgca
     9961 gagtgcatta cggctcgcgg ccaggcctcg gtctgtgatc atgcagccca ccacgaagtg
    10021 cctgcccatg gactgcacct actgctactt gccgttccgc aagatgaacc acttgatgcc
    10081 ggtgacggtt gccgaggctg tggccgcgtc cgtcaacccg tgggcagctc acgatccggc
    10141 gttcgaagtc gtgtggcacg gtggagagcc gctggccacg ggccgtgagc acctggccgc
    10201 gctcatgtcc cctttcgagg gcgtgaagca cagcatccag acgaacgcgg ctctggtgga
    10261 tgacgcctgg tgcgagttcc tgctggagca cgaggtccac gtcggcgtca gcatcgacgg
    10321 ccccgaggac atgaacaccc accgcgtcac cctcgccggc caccccggat tccgcgtcac
    10381 catgcgaggc atcgagcgcc tgcgccgcca cggcatcccg ttctccgcca tcgcggtcgt
    10441 ctccgacccg gcccccgaga acgcggcccg cttctacgac ttcttcgccg agctgggcgt
    10501 caccaccctc ggcgtcaacg tcgaagagga agaaggggtc aaccgcggag ccaaggagtc
    10561 cgaccccgtg cgcacgaccg agttctgggc cgccctcgcg gacgcctggc gggccaatcc
    10621 ggtgatccgg ctgagggaga tccagcgggt gctcaacttc gccggtgccg ttctcggcag
    10681 ccacgacacc gcccccacgc ccacctctgc accttgggat ccgatgccca ccgtcgccta
    10741 cgacggcggg gtgatcatgc tctccccaga gctggcgggg ttcaccgacg cccggttcgg
    10801 cgacttcacc accggcaacg tactcaagga cggcctggac gtcctcgtgg ccgaggccga
    10861 ggaacgcacc ccctggatca ccgagttctg gcagggcgtc gacgcgtgcc gcgacacctg
    10921 ccccgccttc gccttctgcg ggggtgccca cgccgcgaac cggtacttcg agcacgccgg
    10981 ccggttcgac gggaccagga cccggtactg caccaccgcc aaaatcgccc tactcgaagg
    11041 agtcacgcga catgtccatt cacacgccca ctgacgccgc caccctcgtg atggactcgg
    11101 cggagggatt cgagtccctc ctggaggccg ctggcaccgg cgccgtcgcc cgctgggaga
    11161 actcctggac caacgccacc tggagcaacc agcccacctc cgaagccgcg cacgccaagc
    11221 ccgtcgccgc gttcgacaac cgcccgacct gggacaaccc cacggccacc ttcgacaacc
    11281 ggcccacctg ggacaactgg aagaacaagt agcagccgcc gacatcggga cggtcccgcc
    11341 gcgcggggcc gccccgcccc aacgacaagg agcaccatgg ccatccgaac cttcggccac
    11401 gccacgatca ccctgcctga gctggacgag cccggcctct acctgagcaa cgtcgacagc
    11461 ctcgacagct cccgtggcac agtccaggac ttcgtgtacg gggatgccga tctccgatcg
    11521 ctcgacctca cggacaccca actcgtcacc ggccggctct cgggcatccg cgcgaagcgt
    11581 ctcgagttcg aggcggtcaa cctccacggc gtcgagatca gcgacagcga cctcggcacc
    11641 gcgcgctgga ccgagagcaa gctgacccga gtccacttcc gagactgcaa gctgatgggc
    11701 gccgctctgg acggcctggt gctcgacgac gtgctgttcg aaagctgcaa gctcgacttc
    11761 gccacgttcg agaaggtccg cgccaccggc cccgtggcct tcatcggctg cgtcctcaca
    11821 gaggccacat tcgcggactg cgacctgtcc gacaccgtgt tcaccgactg cacgctccgg
    11881 cgcgccgaat tcggcacggg ccgctatcgc aacaccgacc tgcgcgagaa cgatctgtcg
    11941 gccatccgag gggtcgcgaa cctcgccaag gtccgcatcg accccggcca gcagtccgac
    12001 ctcgccgaag ccctcgtgaa cgaactcaac atcaccatcg gggacgactg accctgaagg
    12061 gaggccccgt gcccctgcac atcgcctacg gcgacccatc cgccctccgc gcccgctgcg
    12121 aaatcgccac cgtccggacc actcgccccg aggagaccgc ctacgagccc ggcgcgatca
    12181 tccccgccgg gcagtggcgc cccatgacca aggtggacgt caaggccgtc tcagcccctc
    12241 gccggcccct ggacagcaca ctcgtggaga tcgtccgacc cacgtatcaa gtaggactcc
    12301 tcctcgaaga cctcaccggc ccgctgggcg atccggacgc ggtgtacctc ggtcaagccc
    12361 tggccaagcc cggcatgacc acgaccaccg acaactacga ggacggccgg ctgatcgggc
    12421 tgcacctcga caactgggac aagctccagt acaccgacaa gcacaccgga cgccgcagac
    12481 tctgcctcaa cctcggcccc ggaacccggt acatcatctt cggcaccatc gacgcccaag
    12541 cggtctgccg agccgtccat cccaacgacc acgccgatcg cttcccgcac acccaggact
    12601 accgcgacta cgtcgccagc ggccgcccca tccgcatcat ccgcacacgc ctggcccccg
    12661 gcgagggcta cgtggctccc accgaatact tgctgcacga cggctccacc gaggcccaag
    12721 accggccctc ggcagccgcg ttttggctcg ggcagtggcc ccgcggcatc ctgccgtccc
    12781 tcacctgacc cgtcgacgat gcctcgtctc ccccgccagg agtgggggca tcgcggcctg
    12841 cactcccgca ggtgtggcca accgctcgcc aggggtcagc atctcgcgcc cgggtcagaa
    12901 cagcccttgc tcctcgaact ccggcctcaa tatctcgtcc gggggaccag gcacctccag
    12961 ctgaagcgga cctgcctgcg acacatcaac acgctgcgcg gacccagggc aaagcacgag
    13021 gtccccgtgc gccctcttgt ggtcggccac ccggccccaa cccaccgctc ccccgatggg
    13081 tatcgccgcc accgtccggc cgcacggccc cggcctgtcc ccggtgccca gcacgctcgg
    13141 gcacactacc cgcggatacg tcgccatatt gatgatgatc ggccaacatg gatagaatcg
    13201 ctacctgtta tgaaggttta tacgctcctt cgcgttcact cgatcattga gaaatggcac
    13261 atacctacaa ctgggcatga tccaggcctc gccgggggca tagagggttg acccgtctcc
    13321 accgaggtct acgactactc tgtccgcgcg gcccagcagg gggccagagg tacggggtga
    13381 cgccagcatg cccgcatgac gcggccacct gccagcggct ctgactcaat tcaaagggtc
    13441 gcacttgcat cgtgcactga ccaacctcgc gccaccagcg cctcggcata tggctcggcg
    13501 cgctgccgag gggtagcgaa ggccagcaga tgcgttggac gtgtagctcc aacgaagatc
    13561 agctgagcgg ctctcttaac ggtgcttgtc gctcgatcca ggtctcttcc acttgcaaga
    13621 agattcagca cctcgttcac atcaaacttc ttgcccgtct tgtccaagca gtcaagaagc
    13681 agagtggcac tgtgcgtctc acccttagcg cgttgaatcg tgctcgcaat agatggcacc
    13741 agatcggtct catcggaggt tggcagcaaa gtgcggggcg actgacctct gggcacgtac
    13801 agaaacacct ctcccatacg gttgaggtct gcctcggtta cgctcgtcaa ctcggacaag
    13861 acacgcatga gctgatccgt cagcgactcc cacagaccct catcgtccaa ctgcgcggtg
    13921 agcatgctca gtagtacggc acgcgccttc ccgccagcgg tgactgcctc tcgctccagc
    13981 cgcccgattg ctgggagata gccctccgtc ataggtcgaa ccaaccctcg aacggcattc
    14041 cagacgtgac ttacggcacc gtggctgtca tccgattgcc actgcgtctg agccgagcgg
    14101 gtagttcgga tgagactgcc ccgaacagca tccgcttggg caagaagttc aggtacgtag
    14161 caagcaaggg actggggaaa gttcggagaa cttcctcggt gtcgacgcgc gccaagcacg
    14221 cgcggagggc tctgttgaag gagaggtggt gggacgagag tcgccgccag cctttcgaag
    14281 gccggcacga cttgggcaac cgtactttcg tcataggtga ggagcacgat ggccccctca
    14341 ggccctgccc cgtggatgcg ctgccgacga tgcaccgtca actcgctcgc cagacctgct
    14401 atccgactgc cgaaccgtcg gctgaccggt agttcagcgg ccatgggcag cgggaacgta
    14461 ccggcttcgg tgcgcccggg ctgcccgtcg ttgaagatgc gctgattcac gtcaccgacg
    14521 cgctgcacga cggttcccgt cgacccgaat accttgtcca gtagtcgctc ctgcaccagg
    14581 ctggtgtcct gcatctcgtc caggagaacg aacggaaagc gccgcgacgt ggcatccgcc
    14641 aagtcagggt tccgcaccag gtgctgctcg gcgatcgcga acatgtcctc gtagcggaag
    14701 attcctctgc gagacaggtc ccgtttgagg aggatgaact gcttcccgct ggaggtctcc
    14761 ttcgagaacg gcagactacg cgtggctacc acggcgaggt cgcgggcttc acagacgaaa
    14821 cgggcggtgg ctgcgagctg cctgccgtcc ctctggcgat cgagggttcc gagcagagtt
    14881 cggaagcggg ggtcccgctc aaggagacgg agcgcggctg ctgcatacgc ctcgtcatcg
    14941 actgcctgga tctcaacacc cagggcccgc acagcgggta gagcaaggaa ggtgttggcg
    15001 aacgattgga tcgtcccaat gaagtgtgga taggccagaa gtcttcggcc ggcgggggtt
    15061 gcggcaagtc gtgcagtgat ttcagtcttg gctgtgttgg tgtgcgagag aacgcatatg
    15121 cctctcgtcc gtgagctcca acctgcggca agcagtgcaa gcttcaggcc tatgaggctg
    15181 gttttccccg acccaggtgc cgcttgtaga tcaagagaga tcatgctctg cagaaagtcc
    15241 cactgttcct cgtggggaag ggtgaggccc atcgcggaag ccagcgcctc aatcctatcc
    15301 ttggcgaagg cggcctgctc gtaggggatc gtcatggctc accgcaaagg tgggcaaagg
    15361 cgcgacggag gtacgccggg atgtgtgcct ctgtgagtgg cgtggacttg agcagcctgg
    15421 ccgcatgctg ggctgcgatg gccttgctcg cattgccttt cttcagtggt cggtagattc
    15481 gcagggccgc ctcaggacga ttgacgcccg cggcccgcca ttcttcgacc tcctgtgccg
    15541 cctcaccatc gagctctgca agcctttcag catcaggcca cgaccgctcc gaagctcggg
    15601 cagcacgtac ggcctggtgc atcaccctag ccatggtcca tgacgcagct gccagatcgt
    15661 actcgagggt ccagtggtcg gaaacgaatg tcttcacatt cccgtcgtct ccacgcgtaa
    15721 gggcatcaac gtgtgcggca atctgctccg cagtcatgtc tgatacacac ggcagctcgc
    15781 ctctcatgtc cgtgggagta ccatccggca gcagatctct gtcgcggatg caggccacag
    15841 tgacggggat ctgccgaccc tcccgctgga agatccggct ataccggaac aggcccgtgt
    15901 gaccgacatt gacgacgctg accccactct cgttgaagga gcggccgaca gcctgcgcga
    15961 gggcaggaag cagcaacgcc tccgcatcgc cttccaccac agcgacggag cgggcaaaga
    16021 acagattggc cttggtcacg tcaaggaagc gagaaaggaa agcatagtcg cccgcatcga
    16081 gccgggtgtg tcccggagcc aggctgaacg tgctgccacg cgctacgagg gtgagccatt
    16141 cgacagggac cgcggaggcc aggttggggc tgtgggtagt gagaatgact tggacgcctg
    16201 cggccgctcc ggccgtcccg gccgcccgct cgtacagaag gtccatcaca cgagtctgca
    16261 actgaggatg caggtgggcc tcgggttcct cgatgagcag caaaggcgcg gtctcgctgt
    16321 tccccagcag tagcagctcg gcagccatga acagagcgtt gttgtagccc agcccccgac
    16381 gggtccattc gccagtacca gcgaagagcg tgagctccag ccgttccaac gcccgagcga
    16441 gcgtggcatc gccggccacc ccgatctcgc cccggaggac atctgagcca atcgagaact
    16501 tttcgaggta gttggtgttg atgtcgtcgc gagccgcagc gacggcagca ttgcttgtga
    16561 tgtggtgttc agctcgccgc aggatgccca caagggtgtc ggctgtgtcg gtctcagcgt
    16621 tgaagtcgtc ctgctcttcc ttgaggatcg ccggatagct ggccaggatc tgggaaagcc
    16681 tggatccacg tcccgagcga agctctgcct ccgcatcccg tagcggcctc aggtaggtcg
    16741 ctttcaggag ctcacgggcg gcaccgtcca aagcgggtcc cttgccgtcc ggtccggtcc
    16801 gcgtggtgac agagacacga ttcgagcgct gcggatccat gagttgcgct ctgaatgtga
    16861 catacaaggc gctgccactc gcgtctgtag tgagcagctc gaggaaggta cccttctcct
    16921 ccgcggaaag ccctctgaac ccacaggtaa tcgtgaaggt gtccgagcgg cccccggccc
    16981 cgacatggaa gtcgtccttg gtgacgcggt agtagtccgc tgcagttgtg aggaggcaga
    17041 cccggatggc atccacgatg gccgtcttac cgctgtcgtt ctctcccact agtacggtgg
    17101 tgcccggagc gaagtcaacg cgaagcgagc ggtccgcgtc gccgccctcc tgcccagccg
    17161 ggccgaagat gcgaaagttc tcggcgcgca gatgagccag atacacacgt tcccccgggc
    17221 ggcaagagtg cacccctgag gatgcaggcg tcggctaccg ccccaagttc cccacccgta
    17281 cgcggcttga agcagataat acggccgcca acgtcgtctt ttcggtgaat tccagagatt
    17341 cacccaggcc cactgatgca gtccccatca ccggaccctc tcagcgcggt cggcgcttcg
    17401 gagggaccgg acccgggatg acatcgaggt cgagatgttc cttgaacagg tgaaccaggt
    17461 tggcgccgtc caggagttca aggcgtccgt ggtcgttcgc gaacgcctcg ctcgcccggc
    17521 cgaaccacga ggtcgtcacc aggatgccct tggctgcccg cttgtgctcc acgacgccgg
    17581 cgagggcgga gaccgattcg aagggcacca ccttggcagt gcgtttggcc tgaatgatgc
    17641 acaggcctcg catgaccggg tcggtgttca tcgccacagc atccacaccc tcgtcctgcg
    17701 acggtcgcgt gttgacactg tcgaggccga tggcttcgaa caactgccgg accaaatgct
    17761 cgaattccgt gggcgagagg tccatcagca cgggacggct gtccaggccc gccacgacgt
    17821 ccatgctgtc catcagccgg tacttgctca agtcgaaggt gaccagcgcg cgcaccggct
    17881 ccagctggta cggattcggt gagatcagcg atcgcagccg cttcaggcag gcctgcggat
    17941 cgacttgggt cagcaccagt tcgctgaact cctgcctccc cgcctggaga gtgatcagac
    18001 aggggtgcac ctcgcggccc gtggcacggt cgatggtcgc cacgtgcccg ttcagcgcca
    18061 cggacctcac caccccgtcg gtgtccgccg cgaacaactc gtggacggtc ctcagcgccg
    18121 tctgcgccag tacggacgcg tacagctcgt ggcgctcctt ctcgggcctc gggacaagcg
    18181 tgatctcgtc gcgcgtcttc acgtaccggt aggcgcgggc cgccgggacc acatcttcca
    18241 gcggcaggtc gatctcgacc agcaggtctc ccgtatctgc ctggtaggag acctggtgcg
    18301 ccttcgggaa gccgtgggga tacgtggagg cggccaggac ctggtcgatg aaccactcga
    18361 ccgcttcgac gtcgcgctcc tggtaggcga cgcggcgtgc ctcgatcccg gcattccact
    18421 cctcgatgcg ggcggcctcc tgctggttgc gctcgtcatg gcgggcctgc gccgcatcca
    18481 gcttcccgac ccgcttgtgc tcctcgcgag catggtcacg cagcgcctcg tcgaaccgct
    18541 tgcgtgcagc ctccacctcc gcgtcgtacg aacggcgccc gaagccgagc gcgcccaacc
    18601 atccacgcgg cggctcgggc tcgtactctc cccaccgcgg gaggggaacg ggcttcgtgc
    18661 ggctcttgga cggcgcgaag accgcaggga cgaagtgctg cctgagactg tcgaagctca
    18721 ggggccggcc ctccagcacc gccgcacgta acagtcccgc cagctgctcg acgtcgtgct
    18781 cggtcacgct cgtcttgtcg acggcctcct gggcacgtgc ggcctcgtag gcaaccttct
    18841 cgtcgcgcgc cttgcgcttg gcctccgtct cagcagcctt ctggcgccgc tcacgttcct
    18901 tggcctgccg cgcccgctcg cgcgcgtact cgtcgccccc acccgccacc gccaccccca
    18961 ggtccctgca cgccggtccg ctcaggactt cccccaccca gggtcgtgca atccgcttgc
    19021 ctacccactc gatcactgga acgcccgcaa gcgccctctg cgtccaggcc gggcgagaag
    19081 aactttgacg gctacgctct gtagaacctg cggcgccgtg cccgaggagc ccgtccacgg
    19141 ttcattcggg accatcggaa gacatccctc gacctgacga accgtcatca aagtcagcat
    19201 tgggtcagca ttggtcctgg caaagctgac cccagctggt cacacctggg aaacgtcgag
    19261 agcccggaga gggcctctcg cagcccgcgt cgcccacccc ggcggaacga tctccgcgcg
    19321 ggatacggcc cctctcaggc tgatctcgac ttgtcgggct actttgaaaa accgcaggtc
    19381 aacgcacccg tccgcgtgcc ttaagcggcc ccggcgggag ctgcggcgcc gggatcggag
    19441 ggccgtcgta acccttcact tcgccgtacc gggagccttc catccagtcc ttgcgggctt
    19501 gtacgatctc ctcgttgctc cggccgatcc agttccagaa catgacgatc tcctcctcga
    19561 acggctcgcc gcccaggagc atcaggctcg cgtccgaggc tgcccgcagg ggagttcggt
    19621 gcggccgcag ccgaggtaga gcatcgagcc cgggaggacc gggacgtcgt cgacgtgggc
    19681 ctcgcccgac atcgacagga ccgcgtactc gaagtccggg tcgagcggga gccgggtctc
    19741 ggtgcccgcc gcgagggaga ggtccgcgcc gacgatcggg ctgtacgccg tgcccggcga
    19801 ggtggccgtg tccagggtgc ccaggatgac cgtcgcggtc aggcccgggg aagtcacccg
    19861 cgggagctcc gcgtggtgct ggaagtgcgg ttccacatcg cggtgggcgt ccggcagggc
    19921 cacccacagc tgggcgccgt gcaggaagcg ggcgtgcggg cgcgggctct cctcggagtg
    19981 gctgatgccg cggccggagg tcatcaggcc cagctcgcgc gggcggatcg tggcgaggct
    20041 gcccacgctg tcgcggtgca gcacctcgcc ctcgtggagc cagctcacgg tctggaggcc
    20101 cgagtggggg tggggggcga cctgcatgcc cggctcgtcc gcgatgtcgt ccgggccgta
    20161 gtggtcgacg aagcaccagg cgcccaccat gcggcggccc aggttcggca ggagtcgtcg
    20221 gacctcggtg gactccccga gcttgaccgt gcgggggctg aggagctcgc gtaccggttc
    20281 ggcgacgacg aacccgcggc cgccgcagac ggagagtgcg ggctggcgat cgagattgct
    20341 catgcggaca acctaacggc gggacggcgg ccgcggtcag tggaatgttc ccccggcctt
    20401 gcgtgttgga ggcaccggac agagacacga gagcgggaaa agcggaaggg acgcgatgag
    20461 cacgccgtac ttcgagcacg ggacggcagc cgagcgctgg gcacgggccc ggctcttctt
    20521 cgacgcgaag gagtacgcga cggccgcccg catcctggac acgctggcgg gcgaggcccc
    20581 ggagcagctg gcgccccgcc tgctgctggc ccgcgcctac taccactccg cccagctctc
    20641 ccgcgccgag cgcgagctcc gcgccatcct ggagcgctgg ccggtggagg actacgcaca
    20701 gctgatgctc ggtcgcacac tggagcggag cggccgggcc gccgaggccc gcccgtacct
    20761 gcggatggcc gccgcgatgg ccggtgagtt cccggagtag gggccgctcg gcccggcgca
    20821 tgcggggccc gggctccggc tcggatagcc tgggtcccat atgaaccgcc tgaccacgcc
    20881 tttcggctcc tacgagctca cccgcttccc cgaggacccg cgcgaccggc tccgtgcctg
    20941 ggacgccgcc gacgagtacc tgctgcgcca tctcgacgcc ggtaccggcg agcgcgggcc
    21001 ggtggacctg gccggcgccg ggcagatcac cgtgctcggg gaccgctggg ggacgctgac
    21061 gacagcgctc gccgcgtacc ggccgacgca gatcaccgac tcctccctca cccgctccgc
    21121 caccgcggcg aacctggacc ggaacgggat cgggacctcc aaggcgacgg tcacgctgct
    21181 gaccacccag gatccgccgc ccgggaagat cgacgtactg ctggtgcgcg tgcccaagag
    21241 cctggcgctg ctcgaggacc agctgcaccg gctggccccg cacgtgcacg cgggcaccgt
    21301 ggtcgtcggc ac
//
