LOCUS       NZ_CP102509            21350 bp    DNA     linear   CON 06-JAN-2024
DEFINITION  Streptomyces sp. NBC_00162 chromosome, complete genome.
ACCESSION   NZ_CP102509
VERSION     NZ_CP102509.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. NBC_00162
  ORGANISM  Streptomyces sp. NBC_00162
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8635149)
  AUTHORS   Nielsen,J.B., Gren,T., Mohite,O.S., Joergensen,T.S., Klitgaard,A.,
            Mourched,A.-S., Blin,K., Larsen,T.O., Weber,T., Gotfredsen,C.H. and
            Charusanti,P.
  TITLE     Identification of the biosynthetic gene cluster for pyracrimycin A
            and elucidation of a key reaction during its biosynthesis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8635149)
  AUTHORS   Joergensen,T.S., Gren,T., Blin,K. and Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2022) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 05-AUG-2022
            Assembly Method :: Flye v. 2.9-b1768; Polypolish v. 0.5.0; POLCA
            polisher from MaSuRCA v. 4.0.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 40.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina Nextseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/05/2024 18:03:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,275
            CDSs (total)                      :: 8,175
            Genes (coding)                    :: 7,805
            CDSs (with protein)               :: 7,805
            Genes (RNA)                       :: 100
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 371
            CDSs (without protein)            :: 370
            Pseudo Genes (ambiguous residues) :: 0 of 371
            Pseudo Genes (frameshifted)       :: 186 of 371
            Pseudo Genes (incomplete)         :: 231 of 371
            Pseudo Genes (internal stop)      :: 27 of 371
            Pseudo Genes (multiple problems)  :: 68 of 371
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:41:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1388216
            Orig. end                         :: 1409566
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102509.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Tilmann Weber, Dr.
            Professor, Novo Nordisk Foundation Center for Biosustainability,
            Kemitorvet, 220, 327D 2800 Kgs. Lyngby, Denmark.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21350
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="10"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21350
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21350
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11350](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11350)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    45..58
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     misc_feature    complement(430..444)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     gene            474..953
                     /locus_tag="JIW86_RS07170"
                     /old_locus_tag="JIW86_07170"
     CDS             474..953
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656904.1"
                     /locus_tag="JIW86_RS07170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07170"
                     /product="DUF1801 domain-containing protein"
                     /protein_id="WP_257553008.1"
                     /transl_table=11
                     /translation="MNDTQKPAENTTATDSSSKRFTDEERGAMKERAQELRASARRGSR
                     ADKAREEEAAVLAKIAEMSDSDRVMAERFHAVVKASAPELAPKLWYGMPSYARDGKVVC
                     FFQSAQKFNTRYATLGFSDKANLDEGAMWPTSYALKELTATDEARIGALVKQAAN"
     gene            1103..1969
                     /locus_tag="JIW86_RS07175"
                     /old_locus_tag="JIW86_07175"
     CDS             1103..1969
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020135278.1"
                     /locus_tag="JIW86_RS07175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07175"
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="WP_257553009.1"
                     /transl_table=11
                     /translation="MPGPRAWPRRFTMPGWMRKYTPFLGRILEQLTSIYVLDCATRLAA
                     QAFLGAIPAIFVIAAVSPDWMREQLISTISSTLGLTGPALDQVRAVYAAGDAAAVASTG
                     AVGILVTLLSATACSRALQTTCERSWHLPKAAARLAAWRWLAWIGVWLAALIFQGPVQN
                     AFGTGRALGAVLALVSGTLLWWWTQHLLLGARVPWLPLLPGAILVAVGEQVVTWGSRFY
                     MPRAINRSLEQFGGLGLVFVMLSWLIMLFFVVTVGIAVGYVVAHEPLPARHLGTPADAP
                     EETATRG"
     gene            2076..2351
                     /locus_tag="JIW86_RS07180"
                     /old_locus_tag="JIW86_07180"
     CDS             2076..2351
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JIW86_RS07180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JIW86_07180"
                     /product="hypothetical protein"
                     /protein_id="WP_257553010.1"
                     /transl_table=11
                     /translation="MRNPNPVPVGPEVPGRPELPSLAPSGDPMLTVRFAVPAVPKLLVS
                     RPELLKRLTAGMGGPLTLVSGPAGAGKTVLAAHWAAKGLAPRPPYG"
     gene            2420..4462
                     /locus_tag="JIW86_RS07185"
                     /old_locus_tag="JIW86_07185"
     CDS             2420..4462
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037660.4"
                     /locus_tag="JIW86_RS07185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07185"
                     /product="hypothetical protein"
                     /protein_id="WP_257553011.1"
                     /transl_table=11
                     /translation="MVLPAEVGRPTRAEGVSQSLLVRLAEGLSGQPEPVVLVLDRFDAA
                     RAPAITDGLDFVIRNAAEGLRTVLTSRTDALLPLHRYRAADEITEIRQADLQFSRADAE
                     TLLGKHRLEISPEGIRLLVDRTEGWAAGVRLCALAMQRSTDPEEFLRQFAADRTTIADY
                     LLNEVLDAQPPATQDLLLRACVTDRIHPDLADALTGRDDAARTLAGLAHSNTFLEQVDA
                     TAWYRLHPLFAEVLRAHLRQRCPGLEPRLHGRAARWLARAGQLTEAVTQAAAAGDWEFA
                     AGQLIDNVAIGRLFTGLETDQLGGAFADMPADAKGAAPALVGAARRLADQDLPGCEAGL
                     RRADLYLTDASGPQARLCRAFLGVLAGRLAGDLAATERAAADADDLLERIPPRLLAGHP
                     EIRALILAALGSVELGAGRLDRAESALTAAVEASGGQGTEASLCDALGSLALVELLGGR
                     LRQATEHARASLAVAERSALPPERRARVGHLVLAGVSVEHDDLPAARSHLDLATLAAGP
                     RPEPVAVVETAVIGARLAAAEGDGEGRSPPSTRSGRPRSRPGCPRGRSTSWPSPRRPRT
                     SRAQTPPRPWSSWTRWPRSGRSMRWPGPAPCWRRDAGTTRSSRWPGCRTKRAFRGPCGR
                     RRACSGRRSPRRTAPPRRRGAGSVRRWRWPGLRSCAGCSPRAAPG"
     gene            4435..4761
                     /locus_tag="JIW86_RS07190"
                     /old_locus_tag="JIW86_07190"
     CDS             4435..4761
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="JIW86_RS07190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07190"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_257553012.1"
                     /transl_table=11
                     /translation="MFAESGPWVGRILHQDPQLARLHSWLPSLAPGRAGSAAGERPAVV
                     EALSERETEVLRKAAQLLSTEEIAAELYVSANTVKTHLKSIYRKLSATRRSEAVHRAQD
                     LGIL"
     gene            4845..5042
                     /locus_tag="JIW86_RS07195"
                     /old_locus_tag="JIW86_07195"
     CDS             4845..5042
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671381.1"
                     /locus_tag="JIW86_RS07195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07195"
                     /product="hypothetical protein"
                     /protein_id="WP_215148963.1"
                     /transl_table=11
                     /translation="MRYEFRIAGIVPDALAASFPELDRMPLREQTLFLGTVADEAHLYG
                     LLTRFQSLGMRVVEMRQQPA"
     gene            complement(5054..6385)
                     /locus_tag="JIW86_RS07200"
                     /old_locus_tag="JIW86_07200"
     CDS             complement(5054..6385)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070076.1"
                     /locus_tag="JIW86_RS07200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07200"
                     /product="hypothetical protein"
                     /protein_id="WP_257553013.1"
                     /transl_table=11
                     /translation="MSTPPEPPEPPQPSASSAPSSPSAPAGKAHEGSRAKRIAMSTVSA
                     VLITLTCILVPVSLLTVWVHDIVLDTDRYVSTVSPLASDPAIEAATVHRITEAADVRVD
                     GPRVAADIAAWLESQGLPPRASTAVKALGPQLDSAVDQAVTKVATRFVDSDRFEKVWTE
                     ANRAAHTAVVRALTGEGRGAVEVSDGTVTLDVGVAVERVKEDLVAAGLSPAEKIPEVNK
                     QMVLFQSDKLAKIRNAVHLLDVVGNWLPVLTVVLGAIGVLLARRRRRALVTTTLCAAAA
                     CLILAIGLVIARRYYLDHLPAEVQSPAAAAAVFDTLVRFLRVSIRTAIVLGIVVAIGAY
                     LSGAGRLPVSVRGKAETMADSAARWGSGHGVHTGKVGTWVDAYRRWLTLAALLVIALVF
                     ALWNHPTVLTVLLMVLILLAVLAVLALLAAGGRNSEPTERAGKS"
     gene            6603..7058
                     /locus_tag="JIW86_RS07205"
                     /old_locus_tag="JIW86_07205"
     CDS             6603..7058
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849428.1"
                     /locus_tag="JIW86_RS07205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07205"
                     /product="hypothetical protein"
                     /protein_id="WP_257553014.1"
                     /transl_table=11
                     /translation="MSQQTPTGGNWNTGPAPGTTPLTEGGGDTISGGVLFAAVMLIVSG
                     CLAVFEGIAAIANDDVYLRIGSYVFEFDLTAWGWIHLIIGIIVVLAGIGIFAGSGLARG
                     AGIGLAGLSIILNFMWLPYQPWWAIIIIAIDAIIILALCTGWKKQTG"
     gene            7327..7662
                     /locus_tag="JIW86_RS07210"
                     /old_locus_tag="JIW86_07210"
     CDS             7327..7662
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458961.1"
                     /locus_tag="JIW86_RS07210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07210"
                     /product="SAV_915 family protein"
                     /protein_id="WP_257553015.1"
                     /transl_table=11
                     /translation="MCLFPYEDDPDPEERVPAGPLCVPVRPGTAEVVLRMFRTPLGDRT
                     AVGFTRPDLLAATLGAEQPWIRLSESALRALASPLGVRLVTIDPALSAPAVTPVPARTT
                     AVTVRVL"
     gene            7676..9009
                     /gene="lysA"
                     /locus_tag="JIW86_RS07215"
                     /old_locus_tag="JIW86_07215"
                     /pseudo=""
     CDS             7676..9009
                     /GO_function="GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /gene="lysA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010058601.1"
                     /locus_tag="JIW86_RS07215"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07215"
                     /product="diaminopimelate decarboxylase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTIAVLSDVATGAEDLSIWPASTERLPHGGLAVGGVSSPRSPSGS
                     RPRSTSWTRVRCAGAAGPTGRPSPAPTSTTPRRRSSPARWCAGCRRRDWAWTCVPPGSW
                     SSPSPPASRPSGSCCTATRSRPATWRRRCGSAWGGSSSTVRRRSPGSRPPSDPRGTRRS
                     WCGWCRASRPGATTRSVRARRTRSSGCRSPTGARSTPSPGSWASRSSN"
     gene            complement(9083..9985)
                     /locus_tag="JIW86_RS07220"
                     /old_locus_tag="JIW86_07220"
     CDS             complement(9083..9985)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015576151.1"
                     /locus_tag="JIW86_RS07220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07220"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_257553016.1"
                     /transl_table=11
                     /translation="MTSTDLNTATATATSAGTSAFIPGPATPYQGDIARYWNNEARPVN
                     LRLGDVDGLYHHHYGIGDVDHAALGDADDSAYEKKLIAELHRLESAQAELLLDHLGPIE
                     RDDTLVDAGCGRGGSMVMAHQRFGCKVEGVTLSAKQADFANQRAHELGIEDHVRARVCN
                     MLGTPFETGQAAASWNNESSMYVDLDDLFAEHSRVLEVGGRYVTITGCWNPRYGQPSKW
                     VSQINAHFECNIHSRREYMRAMADNRLVPQAVIDLTSATLPYWELRATSRLVTGIEEAF
                     INSYKDGSFQYLLIAADRI"
     misc_feature    9997..10010
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.68"
                     /tool="antismash"
     gene            complement(10001..11350)
                     /locus_tag="JIW86_RS07225"
                     /old_locus_tag="JIW86_07225"
     CDS             complement(10001..11350)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378420.1"
                     /locus_tag="JIW86_RS07225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07225"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_257553017.1"
                     /sec_met_domain="T1TS (E-value: 5.1e-69, bitscore: 232.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDPGLSPLQSSLPAAAARFGAHVLAHAHASGTEAAVGDARPALP
                     SGPALPFVPVFGPGAVPATVPVPGESIAQHVGEGAAAVRRPSPALERILSGPSGLGTAG
                     LHPARREEPPASPAPEAPVEGHPIPGLYHHPVPEPDPARVEEVSRRIKAWALDEVELYP
                     EDWEGQFDGFHVGRYMVACHPDAPTVEHLMLATRLMVAENAVDDCYCEDHGGSPIGLGG
                     RLLLAHTALDALHTTKEYQPEWAQSLHSDAPRRAYRSAMEYFVRQSTPSQADRYRHDMA
                     RLHLGYLAEAAWAQTEHMPEVWEYLAMRQFNNFRPCPTITDTVGGYELPADLHALPAMQ
                     RVIALAGNATTIVNDLYSYTKELASPGRHLNLPVVIAEREGISDREAYLKAVEVHNDLM
                     HDFEAAAADLAASCPVPSVLRFLRGVAAWVDGNHYWHQTNTYRYSLPDFW"
     gene            complement(11459..12871)
                     /locus_tag="JIW86_RS07230"
                     /old_locus_tag="JIW86_07230"
     CDS             complement(11459..12871)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267883.1"
                     /locus_tag="JIW86_RS07230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07230"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_257553018.1"
                     /transl_table=11
                     /translation="MTVDTSPEAQLEPPKQSSLGTAAARNLATTTKSAPQMQEITSRWL
                     LRMLPWVETKGGTYRVNRRLSYTVGDGRIDFVQDGATVRVIPRELGELALLRGFDDVEV
                     LTALAGRCVQRDFRAGEVLVERGAPSEHIHLIAHGRINQTSVGQYGDEVAVAVLASGDR
                     FGENALLDGAGGWDYTATAETPGTLLTLSRADFAAVLASAPSLQAHVREFSALPRQRQN
                     KHGEAEIAMSAGHTGEAELPGAFVDYEAKPREYELSIAQTVLRVHTRVADLYNEPMNQT
                     EEQLRLTIEALRERQEHELVNNREFGLLHNADFKQRIQTHSGPPTPDDLDELLCRRRGS
                     KFFLAHPKAIAAIGREFNARGLYPDHVDVGGQLVPAWRGVPILPCNKIPISKENTSSIL
                     VMRTGADNQGVIGLRQTGLPEEYEPGLSVRFMGIDERSIISYLVTTYYSAAILVPDALG
                     VLENVQIARRRD"
     misc_feature    complement(13282..13298)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.72"
                     /tool="antismash"
     gene            13338..14078
                     /locus_tag="JIW86_RS07235"
                     /old_locus_tag="JIW86_07235"
     CDS             13338..14078
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036966.1"
                     /locus_tag="JIW86_RS07235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07235"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_257553019.1"
                     /transl_table=11
                     /translation="MSLIEQEQPLLHALRPQDRAALLALGVPRRYEPGAVILPERATTS
                     HVVAITGGWAVVSVTTERGNRLILALRGAGELVGELAAMDLRPRSATVAALGPVAAVVI
                     PGDRFRGFLAGSPAASALVLRQLSSRLRSSDGERRSLASENVLQRLAARLVELVERTGR
                     RNPDASVIIDLPLPQHDLAASVGSTREAVAKALRLLRERGIVRTASRQLVVTDLEPLRL
                     LAGGGGGDGGGGRGGGPRLPRPGV"
     misc_feature    13377..13379
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14148..15059
                     /locus_tag="JIW86_RS07240"
                     /old_locus_tag="JIW86_07240"
     CDS             14148..15059
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010475408.1"
                     /locus_tag="JIW86_RS07240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07240"
                     /product="hypothetical protein"
                     /protein_id="WP_257553020.1"
                     /transl_table=11
                     /translation="MSNSHEAAVHRLVVSADIRGSGQLDQHAKLRSRRAMYEVFEAAFE
                     AIGVPVGQVHVEDRGDGILAALDPAVPPAALVGVWLEEVHQGLREHNRGRLEPLRLRVA
                     MHSGPVSDDGRGLVGRTVDLACRLCDSEPAREVLAADETIGLVFVVSDVLYRTVVADGG
                     RFVEPECYAPYPVRVKETDETAWFHVPRRSRPPLPEPGRVRQDGDDADGGGAGDRRQGD
                     RREADRRQDGDRRTGERRTGERRDGDRRNGAQPAPPPPAKYAITVHGPNQIVDGAEVHG
                     NVTGVTLTRDEGDAADRDGGDE"
     gene            15052..16848
                     /locus_tag="JIW86_RS07245"
                     /old_locus_tag="JIW86_07245"
     CDS             15052..16848
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JIW86_RS07245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JIW86_07245"
                     /product="hypothetical protein"
                     /protein_id="WP_257553021.1"
                     /transl_table=11
                     /translation="MSDAGGAGAGAQGGGEAAGGNAAAAGAAGGGPGAGGPAGGDGRDF
                     AAARSGPFGNRLGDGGYDAARQARAHFFDVRGRNAVVDGTRGDVHLGDHHHYHGGRAAA
                     ARLVTGSVHRDELRRLRRVFQEPPGYGAARTRLERQRLIALCGDPGSGRTYTALSLLDE
                     VTRGRIERLDPRTELHRIDGADLQAEHGYLVEITGDGVFHAERRPADEDRHGEDRARFA
                     EPPAELHLDRLSSLLERHGAYAILVVEAGGFADELLRGRYGTLFRPPSSDGMLRKHLVA
                     LLGHGEVERLAAALALADRADVTAALGLDQLRPHEVESLARLLVDHLAGKLPEEELLAE
                     LRTFAARQAEAWLAAPGRVPPRNRAAMAAATRLAAFRTTVAVFSGSPYSVAADAAERLA
                     WEFAVTMDPAKDPGRALFHDHQDARLAAARAEVFTGDVRFGSRPLGVRKVRLQGRALPW
                     AVLSHAWEGYPNVRGPLGRWLRTLCDDGRPVAWVPAALTVGALCPRDLAFLFQEVVLPM
                     ATSDSPSSAWPRRRRWPTPRPSTRRSGRSCATRCGRGPATRPTRACAARRPWCTVTARS
                     NGPSPPPSTNSGCWPGATTRSC"
     gene            16758..17396
                     /locus_tag="JIW86_RS07250"
                     /old_locus_tag="JIW86_07250"
     CDS             16758..17396
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JIW86_RS07250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JIW86_07250"
                     /product="hypothetical protein"
                     /protein_id="WP_257553022.1"
                     /transl_table=11
                     /translation="MHGYGTVERSVSASLDELGLLAGRDDEELLTHASYSVARLVVGSH
                     GATALARLGSWLGDRRWSRHDLALFTVDRLLWQQPSALWGLEDVPWLAEHPGWPVVAGL
                     LTARPEAAPMLADLVWTGLDTARWRAEVESSLAIWMRLADEDPGLLDVLCGFLPLLVSA
                     QDDIERLRNLVRRMERDPDESLTGATTRRLYDAVPRTVIIPPGASGATS"
     gene            17409..18572
                     /locus_tag="JIW86_RS07255"
                     /old_locus_tag="JIW86_07255"
     CDS             17409..18572
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JIW86_RS07255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JIW86_07255"
                     /product="hypothetical protein"
                     /protein_id="WP_257553023.1"
                     /transl_table=11
                     /translation="MTMNYPVHVGPPAPPAPPGPPAPPAPPVAPHRPWNPQPPHAAAVS
                     PRLEGERPASAQALAGPFIREYRPAWPYRHRSAQYVAVLYYRNRPPRAVGPEGDESFLL
                     RWFTRPYTAFELQLGWHTVSFQAQLPASERGRSFPADVAVRWRVADPCGVARSQVTDVG
                     ALLVPELEQRLRDVSRTYSINHAEEVRDAVNEALTGHELGVRFGMELDVFVTIQADRLS
                     REHGVRVGEVLNQTAVEQFRQRLREIRDDNERLLIQRWAESFQHAMEKGDDAVMAQMMA
                     RNPQDVQEIRKLFRSEQREERQDGMELMTRLIDGGLLERWELGEQAMVVVEFLRSGARR
                     VASEPLPELTDERRRKRALYWEREPDRGSASAAEDGAAAGPPADADG"
     gene            complement(18645..19832)
                     /locus_tag="JIW86_RS07260"
                     /old_locus_tag="JIW86_07260"
     CDS             complement(18645..19832)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010058048.1"
                     /locus_tag="JIW86_RS07260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JIW86_07260"
                     /product="glycoside hydrolase family 64 protein"
                     /protein_id="WP_257553024.1"
                     /transl_table=11
                     /translation="MFRLSKVLASGVAALAVAAGLMVFGPSPSAEAVPATIPLTIKNSS
                     GRSEPVYVYNLGTLLTTGQQGWADANGTFHPWPAGGNPPTPAPDASIAGPANGQTKTIR
                     MPKFSGRVYFSIGQKIVFKLSTGGLVQPAVQNSSDPNRNILFNWSEYTLNDAGLWINST
                     QVDMFSAPYAVGVKAADGTVRNTGRLKPGGYNAVFSQLRSAGWGGLIQNRPDGTPLRAL
                     SPGHGIEAGGIPPGVMNDYINRVWSKYSSSTLTVTPFANQPNTKYYGRVSGNVMNFTNG
                     SGAVVTSFQKPDSDSIFGCYKLLDAPNDLVRGPISRTLCAGYNRSTLLTNPNQPDANGT
                     NFYRDAVTSHYSRIIHGQMADGKAYGFAFDDVGAHESLVHDGNPQEAFMTLEPFN"
     misc_feature    complement(19821..19823)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(19866..19880)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.16"
                     /tool="antismash"
     misc_feature    19867..19881
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 26.03"
                     /tool="antismash"
     misc_feature    complement(20699..20713)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.36"
                     /tool="antismash"
ORIGIN
        1 ccggtggggt ggacgggcag acgctggagc tggtgcatct gcgggtcagc cagatcaacg
       61 gctgcagcgc ctgcgtcgac ggcggcgcca agtcggcccg caaggcggga gtgagcgacg
      121 agcggctggc cacggtcgcc gcctggcggg aggccccgta cttcaccgaa gaggagcggg
      181 cggccctcac gctggccgag gccgcgacgc ggctggccga ccgtcccgac ccggtgagcg
      241 acgaggtctg ggacacggcc gccacctact tcgacgagaa gcagctggcc gcgatcgtcc
      301 tgatgatcgg cgtcaccaac atgttcaacc ggctcaacgc cacgacccgc cagatcgccg
      361 gcgcctgggg atgacgggcc ccggccgggg ccggcgggca aacccgccgg ccccggcggc
      421 ccgaaggcat gacgatgacg tccatcaagc cctgtaccag gaggaaaccc gcaatgaacg
      481 acacgcagaa gcccgccgag aacaccaccg cgaccgacag ctcctcgaag agattcacgg
      541 acgaggagcg cggcgcgatg aaggagcggg cccaggagct gagggcgtcc gcgcgccgcg
      601 gatcgcgcgc cgacaaggca cgggaggagg aagccgccgt gctcgcgaag atcgccgaga
      661 tgtcggactc ggaccgggtc atggccgaac ggttccacgc ggtcgtcaag gcgagcgcgc
      721 cggaactcgc accgaagctc tggtacggga tgccctcgta cgccagggac ggcaaggtcg
      781 tctgcttctt ccagagcgcg cagaagttca acacgaggta cgcgacgctc ggtttcagcg
      841 acaaggcgaa cctcgacgaa ggcgccatgt ggccgacctc gtacgccctg aaggagctga
      901 ccgccaccga cgaggcgagg atcggcgccc tcgtgaagca agcggcgaac tgaggcccgg
      961 ggcaggtccg cgcaccggaa gcgatccggc gtccaccttc ctcaggagac gccggacatg
     1021 ccggagattc ccctctcccc cattcttctc atggagaggc cgccacagcc gacgggcgcc
     1081 gttcccggaa ggaggcgtca ccgtgcccgg accccgtgcc tggccgcgtc gcttcaccat
     1141 gccgggctgg atgcgcaagt acacgccgtt cctgggccgg atcctcgagc agctcacaag
     1201 catctacgta ctggactgcg ccactcggct ggcggcgcag gcgttcctcg gtgcgatccc
     1261 cgccattttc gtcatcgcgg ccgtctcccc cgactggatg cgcgagcagc tgatctcgac
     1321 gatcagctcg accctgggcc tgacgggccc cgcgctggac caggtgcgcg ccgtgtacgc
     1381 ggccggtgac gccgcggccg tcgcgagcac cggagccgtg ggcatcctgg tgaccttgct
     1441 gtccgccacc gcctgcagcc gcgccctgca gacgacctgc gaacggtcct ggcacctccc
     1501 gaaagccgcc gcccggctcg ccgcctggcg ctggctcgcc tggatcggcg tgtggctggc
     1561 cgccctgatc ttccagggac cggtccagaa cgcgttcggc accggccggg cgctcggcgc
     1621 ggtcctcgca ctggtcagcg gcaccttgct gtggtggtgg acccagcacc tgctgctcgg
     1681 cgccagggtc ccgtggctgc cgctgctgcc cggcgcgatc ctggtcgcgg tcggggaaca
     1741 ggtggtcacc tggggatcca ggttctacat gccccgcgcg ataaaccgca gcctggagca
     1801 gttcgggggc ctcgggctgg tcttcgtcat gctgtcgtgg ctgatcatgt tgttcttcgt
     1861 cgtcacggtg ggcatcgccg tgggatacgt agtggcccat gaacccctgc cggcacgcca
     1921 cctgggcact cccgccgacg ccccggagga gacggccacc cgggggtgag tcagaccccg
     1981 gcagggtgac acgactggtg atcaccacag atcacggctt gagtggagag cgtgggccga
     2041 tcacagtgcg tacccggtga accttcggtg gcttcatgcg gaacccgaac cccgtacccg
     2101 tagggcccga ggtcccggga cgtccggagc tcccgagcct ggcgccgtcc ggtgacccga
     2161 tgctcacggt cagattcgcc gttccggccg tgccgaagct cctggtgtcc cggcccgagc
     2221 tgctgaagcg cctgacggcg gggatggggg gcccgctcac cctcgtcagc ggtccggccg
     2281 gcgccggcaa gacggtgctc gccgcccact gggcggccaa gggactcgcg ccgcggcccc
     2341 cgtatggctg accgtcgagc ccggtgatgc tccgggcgcc ttctgggcgt acgtcctgga
     2401 agccctccac cggggcgggg tggtgctgcc ggccgaggtg ggcaggccca cccgcgccga
     2461 aggggtgagc cagtcactgc tggtgcggct ggcggaaggg ctgtccgggc agccggagcc
     2521 cgtggtgctg gtgctcgacc ggttcgacgc ggcccgcgca cccgcgatca cggacggact
     2581 ggacttcgtg atccggaacg ccgccgaggg tctgcgcacc gtgctcacca gccgaacgga
     2641 cgcgctgctt ccactgcacc gctaccgggc ggccgacgag atcaccgaga tccgccaagc
     2701 agacctgcag ttcagccggg cggacgccga aacgctcctc ggcaagcacc ggctggagat
     2761 ctcgccggag ggcatccggc ttctcgtgga cagaaccgag ggatgggcgg cgggggtgcg
     2821 cctgtgcgcc ctggcgatgc agcgcagcac cgaccccgag gagttcttgc gccagttcgc
     2881 cgccgaccgc accacgatcg ccgactacct gctcaacgag gtgctcgacg cccagccgcc
     2941 ggccactcag gatctgctgc tgcgcgcctg cgtcaccgac cggatccacc cggacctcgc
     3001 ggacgcgctg accggccgtg atgacgccgc tcggacactc gccgggctcg cccactccaa
     3061 cacgttcctc gaacaggtcg acgcaacggc ctggtaccgg ctgcacccgc tgttcgccga
     3121 agtcctgcgc gcgcacctgc ggcaacgctg ccccggcctc gagccccggt tgcacgggcg
     3181 ggccgcgcgc tggctcgccc gggccgggca gctgacggag gccgtgacgc aggccgccgc
     3241 cgccggtgac tgggagttcg cggcgggaca gctgatcgac aacgtggcga tcggccggct
     3301 cttcacgggc ctggaaacgg accagctggg cggtgcgttc gccgacatgc cggccgacgc
     3361 gaagggcgcc gcaccggccc tggtcggcgc ggcccgcaga ctggccgatc aggacctgcc
     3421 cggatgtgag gccgggctgc ggcgggcgga cctgtacctg accgacgcct cgggtccgca
     3481 ggcgaggctc tgccgcgcct tcctcggggt cctcgcgggg cggctggcgg gcgacctggc
     3541 ggccaccgag cgtgcggcgg ccgacgccga cgatctgctc gagcgcatcc cgccgcgtct
     3601 gctcgccggg caccccgaga tccgggccct gatcctggcg gccctcggct cggtcgagct
     3661 cggcgccgga cgcctcgacc gcgccgagtc cgcgctgacg gcggcggtcg aggcctccgg
     3721 cgggcagggg acggaggcct cgctctgtga cgcgctggga tcactggccc tggtcgagct
     3781 gctgggcggc cggctgcggc aggcgaccga gcacgcccgc gcctcgctcg ccgtcgccga
     3841 gcggtccgca cttcccccgg agcgccgggc acgtgtcggc cacctcgtcc tggcgggcgt
     3901 ctcggtcgag cacgacgacc tgccggccgc ccgctcccat ctcgacctgg cgaccttggc
     3961 ggcgggtccc cgtccggagc ccgtggccgt ggtcgagacc gccgtcatcg gcgcgcggct
     4021 ggccgcggcc gagggcgacg gggaggggcg ctcgccgccg tccacgcgct cgggccggcc
     4081 gcgttcccgt cccggctgtc cgcgtgggcg ctcgacgagc tggccgtcgc cgaggcgtcc
     4141 gcgtacctcg cgcgcgcaga cgccgccgcg gccctggtcg tcctggacgc ggtggcctcg
     4201 gagcggccgg agcatgcgct ggcccgggcc cgcgccctgc tggcggcggg acgcggggac
     4261 gacgcggtcg agtcgctggc cgggctgtcg gacgaagcgg gcgttccgag gcccgtgcgg
     4321 gcgcaggcgt gcctgctccg ggcgcagatc gccgcgtcgg acggcgcctc cgaggagacg
     4381 cggcgccggc tcggtcaggc gctggcgctg gcccggcctg aggagctgcg ccggatgttc
     4441 gccgagagcg gcccctgggt aggccggatc ctgcaccagg acccgcagct ggcccggctg
     4501 cacagctggc tgccctccct cgccccgggg cgtgccggct ctgcggccgg cgagcggccg
     4561 gccgtggtgg aggcgctgag tgagcgggag accgaggtgc tgcgcaaggc cgcacagctg
     4621 ctgtccacgg aggagatcgc cgccgagctg tacgtgtcgg ccaacacggt caagacccat
     4681 ctgaagagca tctaccgcaa gctctccgcc acccggcgca gcgaggccgt ccaccgggcc
     4741 caggacctcg ggatcctgtg actcccccga accaggcgat gccgagaagg tggtcgggga
     4801 ccgaccatgg aaggtgaggt cggacgagag aggtgagtgc tctcatgcgc tacgaattcc
     4861 gcatagcggg catcgtgccg gacgcactcg ccgcgagctt ccccgagctc gaccggatgc
     4921 ccctgcggga gcagaccctc ttcctgggca ccgtggcgga cgaggcccac ctgtacgggc
     4981 tcctcacccg cttccagtcc ctgggcatgc gcgtggtcga gatgcgtcag cagcctgcct
     5041 gacggggcgg cggctacgac tttccggcac gctcggtggg ttcgctgttg cggccgccgg
     5101 ccgcgaggag cgcgagtacg gcgagcacgg cgaggaggat gagcaccatc agcagcaccg
     5161 tcagcaccgt cgggtggttc cacagcgcga acaccagcgc gatcaccagc agggccgcga
     5221 gggtgagcca ccgccggtag gcgtccaccc aggtaccgac cttgccggtg tgcaccccgt
     5281 gaccactgcc ccagcgcgcg gcggagtcgg ccatggtctc ggccttcccg cgcacggaga
     5341 ccggcagtcg gccggctccg gacaggtagg cgccgatcgc caccacgatt cccagcacga
     5401 tcgcggtacg gatgctgacg cgcaggaagc ggacgagggt gtcgaagacg gcggcggccg
     5461 cggccgggga ctgcacctcc gccggcaggt gatcgaggta gtagcggcgg gcgatcacga
     5521 ggccgatggc gaggatcagg caggccgcgg ccgcgcagag ggtggtggtc accagtgccc
     5581 tgcgacggcg ccgggcgagc agcaccccga tggccccgag aaccacggtg agcacgggca
     5641 gccagttgcc gacgacgtcg agcaggtgca ccgcgttcct gatcttggcc agcttgtcgg
     5701 actggaagag caccatctgc ttgttgacct cggggatctt ctccgccggg gagaggccgg
     5761 cggccaccag atcctccttg acccgctcga ccgcgacgcc aacgtcaagg gtgacggtgc
     5821 cgtcgctgac ctcgaccgcg ccccggccct caccggtgag cgcgcgcacg acggccgtgt
     5881 gtgcggcccg gttggcctcg gtccacacct tctcgaaccg gtcgctgtcg acgaagcgcg
     5941 tcgccacctt ggtgacggcc tggtcgacgg ccgagtcgag ctgcggcccc agcgccttga
     6001 cggccgtact ggcgcgcggc ggcagtccct gggactccag ccacgccgcg atgtccgccg
     6061 cgacccgggg gccgtcgacc cggacatcgg ctgcctcggt gatgcggtgg acggtggcgg
     6121 cctcgatcgc ggggtcggat gcgagcgggg acaccgtcga cacgtaccgg tcggtgtcca
     6181 gcacgatgtc gtgcacccac acggtgagca gggagaccgg tacgagaatg caggtgagcg
     6241 tgatcagcac ggccgagacc gtgctcatcg cgatccgctt ggcgcgggag ccctcgtgcg
     6301 ccttgccggc cggggccgac ggcgacgacg gggcggacga cgcggacggc tggggcggct
     6361 cgggcggctc gggcggcgta ctcatggcac tcccagggga cgaccgcggc gaagctgccg
     6421 ctgccgtcca ttggacacgc accgtagcga cgttcgcacg ccgggttgct ccctccgggc
     6481 ggcgccgtgg cccagtagcg gtacgaagat cacccgcatc gggtgatcac gggaacccgc
     6541 ttcctcgtga tgctgggagg aaggcacggc cggcccgcaa cgacagctgt gaggtgactt
     6601 ccatgagcca gcagacaccg accggaggga actggaacac cggacccgct cccggcacga
     6661 caccactgac cgaaggtggc ggcgacacga tcagcggcgg cgtgctcttc gccgccgtga
     6721 tgctgatcgt ctcgggctgc ctggccgtgt tcgagggcat cgcggccata gcgaacgacg
     6781 acgtctacct caggatcggg agctacgtct tcgagttcga cctgacggcg tggggctgga
     6841 tccacctcat catcggaatc atcgtcgtcc tcgccgggat aggcatcttc gccggctcgg
     6901 gcctggcccg tggagcgggc atcgggctgg caggcctcag catcattctc aacttcatgt
     6961 ggctgccgta tcagccctgg tgggcgatca tcatcatcgc gatcgacgcg atcatcatcc
     7021 tggccctgtg caccggctgg aagaagcaaa ccggctgacg ccggcgacag accctgctcg
     7081 gcgcgccgcc cggccctgcc cggcgacgcg ccgagcaggg ctgcgcgctg ccgggggcgg
     7141 acgcatccct gacgctgccc gactccgcgt cagggacccg tatgaactcg gccggtcgtc
     7201 gtcaaggacc cgtcatgggg tggcggcagg tgcgggaacc cggggatagc ttcggtgtcg
     7261 cgccccggac tgcctccccg cacccggggc ctcaaccgcc actcgtggtt cctccgggag
     7321 ggccccatgt gtttgttccc gtacgaagac gaccccgatc ctgaagaacg cgtcccggcc
     7381 ggacccctct gcgtgcccgt ccggccggga acagcggagg tggtgctccg gatgttccgc
     7441 acccctctcg gcgaccgcac cgcagtcgga ttcacccgcc ccgacctgct ggccgcgacg
     7501 ctcggcgcgg agcagccctg gatccggctg tccgagtccg cgctccgcgc gctggcttcg
     7561 ccgctcggcg tgcgcctggt gacgatcgac ccggccctct ccgctcccgc cgtcaccccg
     7621 gtgccggcgc ggacgaccgc cgtcacagtc cgcgttctct gagggggaag tcccgatgac
     7681 cattgccgta ctctccgacg tcgccaccgg cgcggaggat ctgtccattt ggcccgcctc
     7741 cacggagcgg ctcccgcacg gcggcctggc cgtcggcggg gtctcctcgc cgaggtcgcc
     7801 gagcggttcg agaccccggt ctacgtcctg gacgagggtg aggtgcgcgg gcgctgccgg
     7861 acctaccggg aggccttccc cggcgccgac gtccactacg ccgcgaaggc gttcctctcc
     7921 cgcgcgatgg tgcgctgggt gcaggaggag ggactgggcc tggacgtgtg ttccgccggg
     7981 gagctggagc tcgccgtcac cgccggcttc ccgcccgagc ggatcgtgct gcacggcaac
     8041 gcgaagtcgc cccgcgacct ggaggcggcg ctgcggctcg gcgtggggcg gatcgtcatc
     8101 gacggtccgt cggagatcgc ccggatcgcg gccgccgtcg gacccgaggg gcaccagaag
     8161 gtcatggtgc gggtggtgcc gggcgtctcg gccgggggcc acgacaagat ccgtacgggc
     8221 acggaggacc agaagttcgg gctgtcgctc accgacgggg gcgcgcagca cgccgtcgcc
     8281 cggatcctgg gccagccgca gctcgaactg accggcctgc actgccacat cggatcccag
     8341 atcaccgacg tgaagcccca cctggtggcc ctgcgccgca tggtcgggct gatggcccgc
     8401 atccgtgaca cccacggaat cgtcctgccc gaactggaca tgggcggcgg ccacggcatc
     8461 gcctaccggc ccggcgaacc cgccctcgac ctcaccgcgc tcgcccgacg gctgcgcgcc
     8521 gagctggtcg aagggtgcgg tgcggcccgg ctgaccgtgc cccggctcct catcgaaccc
     8581 gggcgggccg tcgtggggcc ggcgggagtc gccctctacc gggtactcgc cgtcaaacac
     8641 accggcgaga gggtgttcgt cgccgtcgac ggcggcatga gcgacaaccc gcgccccgcc
     8701 ctgtacgggg tgcgctacgc gccccgcctg atcggccgcc actcgacggc cggcccccgt
     8761 acggccacgg tcgtcggccg gcactgcgag gccggcgaca tcctcgcggc cgacgtggaa
     8821 ctgcccgacg acatccaccc cggcgacctg ctcgccgtac ccgtggccgg tgcgtatcag
     8881 ctgtccatgg cctccggcta caacctcgtc ggccgccccg cggtcatcgc ggtccacgag
     8941 ggcgcggccc gggtcctcgt acggcgcgag acgctggagg acttccgcaa ccgggacatc
     9001 ggcgcataga gcctcgcgcc gacgctgaaa gggccgggtc cgtcgggtga cgggtccggc
     9061 cctttcaggc ggcggcggtc ggtcagatgc ggtcggccgc gatcaggagg tactggaagg
     9121 agccgtcctt gtaggagttg atgaacgcct cttcgatgcc ggtgaccagg cgcgaggtgg
     9181 cccgcagctc ccagtagggc agggtcgcgg aagtcaggtc gatgacggcc tgcggtacga
     9241 ggcggttgtc ggccatggcg cgcatgtact cccggcggga gtggatgttg cactcgaagt
     9301 gcgcgttgat ctgggagacc cacttcgagg gctggccgta acgcgggttc cagcagcccg
     9361 tgatggtcac gtagcggccg ccgacctcga ggacgcggga gtgctcggcg aagaggtcgt
     9421 ccaggtcgac gtacatgctc gactcgttgt tccacgaggc cgcggcctgc ccggtctcga
     9481 agggcgtgcc gagcatgttg cagacacggg cgcggacgtg gtcctcgatg ccgagttcat
     9541 gggcgcgctg gttggcgaag tcggcctgct tggccgacag ggtgacgccc tcgaccttgc
     9601 atccgaagcg ctggtgggcc atgaccatcg aaccgccgcg gccgcagccg gcgtccacga
     9661 gcgtgtcgtc gcgctcgatg gggccgaggt ggtccaaaag cagttcggcc tgcgccgact
     9721 ccaggcggtg gagctcggcg atcagcttct tctcgtatgc gctgtcgtcg gcgtcgccga
     9781 gggcggcgtg gtccacgtcc ccgatgccgt agtggtggtg gtaaaggccg tcgacgtcgc
     9841 cgagccgcag gttcacgggc ctggcctcgt tgttccagta acgggcgatg tccccctgat
     9901 agggcgtcgc cgggccaggg ataaatgccg aggtaccggc cgaagtggcg gtggcagtgg
     9961 cggtgttgag atcggtgcta gtcatggata catcccatct ttaccagaaa tcgggcaggc
    10021 tgtagcgata ggtgttggtc tggtgccagt agtggttgcc gtcgacccac gcggccactc
    10081 ccctcaggaa gcgcagcacg ctcgggacgg gacaggaggc ggccaggtcg gcggccgcgg
    10141 cctcgaagtc gtgcatgagg tcgttgtgga cctcgaccgc cttcaggtag gcctcccggt
    10201 cggagatgcc ctcacgttcc gcgatcacca cgggcaggtt caggtgccgg ccggggctgg
    10261 cgagttcctt ggtgtaggag tacaggtcgt tgacgatggt ggtggcgttc ccggcgagtg
    10321 cgatgacccg ctgcatggcg ggcagggcat gcaggtccgc gggcagttcg tagccgccga
    10381 cggtgtccgt gatggtgggg caggggcgga agttgttgaa ctgccgcatc gccaggtact
    10441 cccacacctc gggcatgtgc tccgtctggg cccacgcggc ctcggcgagg taaccgagat
    10501 gcagacgggc catgtcgtgc cggtaccggt cggcctggga gggtgtggac tgccggacga
    10561 agtactccat ggcggagcgg taggcacgcc gaggcgcgtc cgagtggagc gactgcgccc
    10621 actccggctg gtactccttc gtcgtgtgca gggcgtcgag ggcggtgtgc gccagcagca
    10681 ggcgtccgcc gaggccgatg ggcgagccgc cgtggtcctc gcagtagcag tcgtcgaccg
    10741 cgttctcggc gaccatcagc cgcgtggcga gcatcaggtg ctcgacggtg ggcgcgtccg
    10801 gatggcaggc gaccatgtag cgcccgacgt ggaagccgtc gaactggccc tcccagtcct
    10861 cggggtagag ctcgacctcg tccagcgccc atgccttgat cctgcggctg acctcctcca
    10921 cccgcgccgg atcgggctcc ggcaccgggt ggtggtagag gcccgggatc ggatgaccct
    10981 ccaccggcgc ctcgggcgcc ggggacgccg gtggctcctc gcgccgggcc gggtgcaggc
    11041 ccgccgtgcc caggccgctg gggccgctca ggatccgttc cagggcaggg ctcggccgcc
    11101 tcaccgccgc cgcgccctcc cccacgtgct gagcgatcga ttcgccgggg acgggcaccg
    11161 tcgcgggcac ggcccccgga ccgaagacgg gaacgaaggg cagggcgggc cctgaaggca
    11221 gggcggggcg ggcgtcgccg acggcggctt cggttccgga ggcgtgcgcg tgggcgagga
    11281 cgtgggcccc gaagcgggcc gcggcggcag gcaggctcga ctgcagaggg gaaagcccag
    11341 gatcgggcat ccgtagctcc ttggtgaggt gggtgggctg tcccggatcc cgggcatgct
    11401 cggtcggccc gggagggtcc gggctgtcgt gaccgtgggg aagttctccg gacagggcct
    11461 agtcgcgcct gcgggcgatc tgcacgttct ccagcacgcc gagcgcgtcg ggcaccagga
    11521 tcgcggcgga atagtaggtg gtgaccaggt aggagatgat cgacctctcg tcgatgccca
    11581 tgaagcgcac cgacagaccc ggctcgtact cctccggcag accggtctgg cgcaggccga
    11641 tgacgccctg gttgtccgcg ccggttcgca tgacgaggat cgagctggtg ttctccttgc
    11701 tgatggggat cttgttgcag ggcaggatcg ggaccccgcg ccaggccggg accagctgcc
    11761 cgccgacgtc gacgtggtcc gggtagagcc cgcgggcgtt gaactcgcgc ccgatcgcag
    11821 cgatcgcctt ggggtgggcg aggaagaact tggagccgcg gcggcggcag agcagctcgt
    11881 cgaggtcgtc cggagtgggc gggccggagt gggtctggat ccgctgcttg aagtcggcgt
    11941 tgtgcagcag gccgaactcc cggttgttca cgagttcgtg ctcttgccgc tcgcgcagcg
    12001 cctcgatggt gagccggagt tgctcctcgg tctggttcat cggctcgttg tagaggtcgg
    12061 cgaccctcgt gtggacccgc agaacggtct gcgcgatgga gagttcgtac tcgcgcggct
    12121 tggcctcgta gtcgacgaag gcgccgggca gttcggcttc gccggtgtgg cccgccgaca
    12181 tggcgatctc ggcctcgccg tgcttgttct gccgctgacg gggcagcgcg ctgaactccc
    12241 ggacgtgggc ctggaggctc ggcgccgagg ccagcacggc ggcgaagtcg gcgcgggaga
    12301 gcgtgagcag ggtgccgggg gtctcggcgg tggcggtgta gtcccacccg ccggccccgt
    12361 cgagcagggc gttctcaccg aaccggtcgc cgctggcgag cacggcgacg gcgacctcgt
    12421 caccgtactg gccgacggag gtctggttga tgcggccgtg cgcgatcagg tggatgtgct
    12481 cggagggggc accgcgctcg accagcacct cgccggcccg gaagtcacgc tggacgcacc
    12541 ggccggcgag cgcggtcagc acctccacgt cgtcgaagcc gcgcagcagg gccagttcgc
    12601 cgagctcgcg ggggatcacc cggacggtgg cgccgtcctg gacgaagtcg atgcgcccgt
    12661 cgccgacggt gtaactcagc cgccggttca cccggtaggt gccgcccttg gtctccaccc
    12721 aggggagcat cctcagcagc cagcgggagg tgatctcctg catctggggg gcggacttgg
    12781 tcgtggtggc aaggttgcgg gcggccgccg tgcccaggct ggactgcttc ggcggctcca
    12841 gctgcgcttc cgggctggtg tcaacggtca tcgggcgagc tctccttcgt aagggaggcg
    12901 atcggcatag gtgcacgtca ccggtgaaag aggaaaaaga gggcgaatat ccgggaatcc
    12961 gtccagatcc ggtggaacat taacggccgg taccgccatc cgccccgcct gaatcgctgg
    13021 cattacctcg atgcagtgat cttgtcccgc agggtgtttg ccggggcgac cgacggtatt
    13081 cggactggtc gagagcgcgc ccggcacgcg gcgcgaccgc tcgccaggcc cgatccgacg
    13141 gctcaccaga ggaatccggc caaattcacc accgaactcg accgccgatg gccgccacac
    13201 tccccaccgg cccctccgct ctcgcccgcg gcggattcgg tcaactgccg tgcacccgca
    13261 gccattgacg tgtatgtgtc attgcgtggg gcttgccatg aggtcggtgg gccggtgccg
    13321 gtacgggagc ggtcgacgtg agtctcatcg aacaggagca gcccctgctc cacgcgttac
    13381 gcccgcagga ccgggcggcg ctgctggccc tcggcgtacc tcgccgctac gagcccggtg
    13441 cggtcatcct gccggaacgc gccaccactt cccacgtcgt ggcgatcacc ggcggctggg
    13501 cggtggtgtc ggtgaccacc gagcgcggca accgcctgat cctcgccctg cgcggcgccg
    13561 gggagctggt gggcgagctg gccgccatgg acctgcggcc gcgcagcgcc accgtggccg
    13621 ccctcgggcc ggtggccgcc gtggtgatcc cgggcgaccg gttccgcggc ttcctcgccg
    13681 gcagccccgc cgccagcgcg ctcgtgctgc gccagctcag ctcgcggctg cgcagctccg
    13741 acggcgaacg ccgctcgctg gcctcggaga acgtgctcca gcggctcgcg gcacggctcg
    13801 tcgaactggt cgagcggacc ggccgccgca accccgacgc gagcgtcatc atcgacctgc
    13861 cgctcccgca gcacgacctg gccgcgtccg tgggctcgac ccgcgaggcg gtggccaagg
    13921 ccctgcgcct gctgcgcgag cggggcatcg tccgcaccgc ttcgcggcag ttggtggtca
    13981 ccgacctcga accgctgcgg ctgctcgccg gcgggggcgg cggtgacggg ggcgggggca
    14041 ggggcggggg cccgcgccta ccgcggccgg gtgtgtaaac ggctacatac agcatgccgg
    14101 ggcgccacca tcctgggcgt gtcggttcgg cgttccaggg gggcggagtg agcaacagtc
    14161 atgaggcggc cgtgcaccgg ctggtggtga gcgcggacat cagagggtcg ggtcaactgg
    14221 accagcacgc caaactgcgg tcgcggcgcg cgatgtacga ggtcttcgag gcggccttcg
    14281 aggcgatcgg ggtacccgtc ggacaggtac acgtcgaaga ccgcggcgac gggatactgg
    14341 ccgcgctgga cccggccgta ccgcccgcgg ctctggtggg ggtgtggctc gaagaggtcc
    14401 accagggcct gcgcgagcac aaccggggac ggctggagcc actgcggctg cgcgtcgcca
    14461 tgcacagcgg gcccgtcagc gacgacggcc gggggctggt gggccggacc gtggacctgg
    14521 cctgccggct gtgcgacagc gagccggcgc gggaggtgct ggccgcggac gagacgatcg
    14581 gactggtctt cgtggtctcg gacgtcctgt accgcacggt ggtcgccgac ggcggccggt
    14641 tcgtcgagcc cgagtgctac gcgccgtatc ccgtacgcgt caaggagacc gacgagacgg
    14701 cctggttcca cgtgccccgg cgctcccggc cgccgctgcc ggagcccggg cgagtgcggc
    14761 aggacgggga cgacgccgac gggggcggcg ccggggaccg gaggcagggc gaccggcggg
    14821 aagcagaccg ccggcaggac ggggaccggc ggacggggga acgacggacc ggggaacggc
    14881 gcgacggaga ccggcgcaac ggcgcgcagc ccgcgccgcc gccgcccgcg aagtacgcga
    14941 tcaccgtgca cggacccaat cagatcgtgg acggcgcgga ggtgcacggg aacgtcaccg
    15001 gtgtgaccct cacgcgcgac gagggcgacg ccgcggaccg ggatggtgga gatgagtgac
    15061 gcaggcggcg ccggagccgg cgcacagggc ggcggagagg ccgcgggcgg gaacgcggcc
    15121 gccgccgggg cggccggcgg cggaccgggc gcgggaggtc ccgcgggcgg cgacggccgg
    15181 gacttcgccg cggcccgcag cggtccgttc ggcaacaggc tgggggacgg gggctacgac
    15241 gcggcgcggc aggcacgcgc gcacttcttc gacgtgcgcg ggcgcaacgc cgtcgtcgac
    15301 ggcacccggg gcgacgtcca cctgggcgac caccaccact accacggcgg ccgggccgca
    15361 gccgcccggc tggtcaccgg ctccgtgcac cgcgacgaac tccggaggtt gcggcgggtg
    15421 ttccaggaac cgcccggcta cggggcggcg cggacccgcc tggagcggca gcggctgatc
    15481 gcgttgtgcg gtgacccggg cagcggacgc acgtacacgg cgctttccct gctcgacgag
    15541 gtgacgcgcg gccgcatcga gcggctggac ccgcgcaccg agctgcaccg catcgacggg
    15601 gccgacctcc aggcggagca cggctacctg gtggagatca ccggggacgg cgtgttccac
    15661 gccgagcggc gcccggccga cgaggaccgg cacggggagg accgggcccg gttcgccgaa
    15721 cctccggccg aactgcacct ggaccggctc agctcgctgc tggagcggca cggcgcgtac
    15781 gcgatcctgg tcgtcgaggc gggcggcttc gcggacgagc tgctccgggg gcggtacggc
    15841 acgctgttcc ggccgccctc gtccgacggc atgctgcgca agcacctggt ggccctgctg
    15901 gggcacggcg aggtggagcg gctggcggcg gccctggccc tggccgaccg ggcggacgtg
    15961 acggcggccc tcggactgga ccaactgcgg ccccacgagg tcgagtcgct ggcccggctc
    16021 ctcgtcgacc accttgcggg gaagctgccc gaggaggaac tcctggccga gctgcggacc
    16081 tttgcggcgc gacaggcgga ggcctggttg gcggcgccgg ggcgggtgcc gccccgcaac
    16141 cgggcggcga tggcggcggc gacccggctg gccgccttcc gcacgacggt ggcggtgttc
    16201 agcggttcgc cgtacagcgt ggccgccgac gccgccgagc ggctggcctg ggagttcgcg
    16261 gtcaccatgg acccggcgaa ggatccgggc cgggcgctgt tccacgacca ccaggacgcc
    16321 cggctcgcgg ccgcgcgggc cgaggtgttc accggggacg tccggttcgg cagccggccg
    16381 ctgggcgtgc gcaaggtacg cctccagggc cgggcgctgc cctgggcggt gctgtcccac
    16441 gcctgggagg gctaccccaa cgtgcgcggg cccctgggcc gctggctgcg gacactgtgc
    16501 gacgacggcc ggcccgtcgc atgggtgccc gccgcgctca ccgtcggggc gctgtgcccg
    16561 cgcgacctgg cgttcctgtt ccaggaggtg gtgctgccga tggcgacctc ggactccccg
    16621 agcagcgcgt ggccgcggcg acggcgctgg cctacgccgc gtccctcgac gaggcggtcc
    16681 ggccgatcgt gcgcgacacg gtgcgggcgt gggcccgcga cgaggccgac gcgggcctgc
    16741 gcagcacggc ggccctggtg cacggttacg gcacggtcga acggtccgtc tccgcctccc
    16801 tcgacgaact cgggctgctg gccgggcgcg acgacgagga gctgctgacg cacgcctcgt
    16861 acagcgtggc gcggctggtc gtcggctccc acggggcgac cgcactggca cggctgggat
    16921 cctggctggg cgaccgccgc tggagccggc acgacctggc cctgttcacc gtggaccggc
    16981 tgctctggca gcagccgtcc gccctgtggg gcctggagga cgtgccctgg ctcgcggaac
    17041 acccgggctg gccggtggtg gcggggctgc tcaccgcccg gccggaggcc gcccccatgc
    17101 tggcggacct ggtgtggacc ggactggaca ccgcccggtg gcgggcggag gtggagtcct
    17161 ccctcgccat ctggatgcgt ctcgccgacg aggaccccgg gctgctggac gtcctgtgcg
    17221 gcttcctccc gctcctggtg agtgcgcagg acgacatcga gcggctgcgg aacctggtgc
    17281 ggcgcatgga gcgcgacccc gacgagtcct tgaccggggc caccacgcgg cggctgtacg
    17341 acgccgtgcc gcggaccgtg atcatcccgc cgggcgcgtc cggcgccacg agctgagaag
    17401 acggagtgat gaccatgaac taccccgtac acgtcggccc gcccgccccg cccgccccgc
    17461 ccgggccgcc ggccccgcca gccccgcccg tcgcgccgca ccgcccctgg aacccgcagc
    17521 cgccccatgc ggccgccgtg tccccccggc tggagggcga gcgcccggcg tccgcacagg
    17581 cgctggccgg ccccttcatc cgcgagtacc gtccggcctg gccgtaccgg caccgcagcg
    17641 cccagtacgt ggccgtgctc tactaccgca accgtccgcc gcgggcggtg gggcccgagg
    17701 gcgacgaaag cttcctgctg cgctggttca cccgcccgta cactgcgttc gaactccagc
    17761 tgggctggca caccgtctcg ttccaggccc agttgccggc gtcggagagg ggccggtcct
    17821 tccccgccga cgtggccgtc cggtggcggg tggccgaccc ctgcggcgtt gcccggagcc
    17881 aggtcaccga cgtgggcgca ctgctcgtgc cggaactgga gcagcggctg cgcgacgtat
    17941 cgcgcaccta ctcgatcaat cacgccgagg aggtccgcga cgcggtcaac gaggcgctga
    18001 ccgggcacga gctgggcgtc cggttcggca tggaactgga cgtgttcgtg acgatccagg
    18061 cggaccggct gagccgggag cacggcgtac gggtcggcga ggtcctcaac cagaccgccg
    18121 tggaacagtt ccgccagcgg ctgcgggaga tccgggacga caacgagcgc ctcctcatcc
    18181 agcgctgggc ggaaagcttc cagcacgcca tggagaaggg cgacgacgcc gtcatggcac
    18241 agatgatggc ccgcaacccg caggacgtgc aggagatccg gaagctgttc cgcagtgagc
    18301 agcgcgagga gcgccaggac ggcatggagc tcatgacccg gttgatcgac ggcgggctgc
    18361 tggagcgctg ggagctcggc gaacaggcca tggtggtcgt ggagttcctg cggtcgggcg
    18421 cccgccgggt ggcctcggag ccgctgcccg agctgacgga cgagcggcgg cgcaagcgcg
    18481 ccctctactg ggagcgcgag ccggaccggg gctccgcctc ggctgccgag gacggggcgg
    18541 ccgccggtcc ccccgcagac gccgacgggt gacggccgcc gcccggcccg aggagggcgc
    18601 ggcggggggc gccccgccga cgccctacgg gtcctggtcc tggcctagtt gaagggttcc
    18661 agcgtcatga aggcctcttg cgggttgccg tcgtgcacca gcgactcgtg ggcgcccacg
    18721 tcgtcgaagg cgaagccgta cgccttaccg tcggccatct gtccgtggat gatgcgggag
    18781 tagtggctgg tgacggcgtc gcggtagaag ttggtgccgt tcgcgtcggg ttggttgggg
    18841 ttggtcagga gcgtcgaccg gttgtagccc gcgcacaggg tgcgggagat cgggccgcgg
    18901 acgaggtcgt tgggtgcgtc caggagcttg tagcagccga agatgctgtc ggagtccggc
    18961 ttctggaagc tggtgaccac cgctcctgag ccgttggtga agttcatgac gttgcccgag
    19021 acccggccgt agtacttggt gttcggctgg ttcgcgaacg gcgtcacggt gagcgtggag
    19081 gagctgtact tgctccagac ccggttgatg tagtcgttca tgacgccggg cgggattccg
    19141 cccgcctcga tgccgtgacc gggcgagagc gctcgcagcg gcgtgccgtc ggggcggttc
    19201 tggatcagtc cgccccagcc ggccgaacgc agttggctga agacggcgtt gtagccgccc
    19261 ggcttcagcc ggccggtgtt cctgaccgtg ccgtcggccg ccttcacacc caccgcgtag
    19321 ggagccgaga acatgtcgac ctgggtactg ttgatccaca ggccggcgtc gttgagcgtg
    19381 tactcggacc agttgaacag gatgttgcgg ttggggtcgg agctgttctg cacggcaggc
    19441 tgcaccaggc cgccggtgct cagcttgaag acgatcttct ggccgatgga aaagtagacg
    19501 cgtcccgaga acttgggcat ccggatcgtc ttggtctgcc cgttggccgg acccgcgatc
    19561 gacgcgtcgg gcgcgggggt ggggggattg cctcccgcgg gccaagggtg gaacgtgccg
    19621 ttggcgtcgg cccagccctg ctggcccgtc gtgagcaggg ttcccaggtt gtagacgtag
    19681 accggctcgc tgcgccccga gctgttcttg atcgtgagcg ggatggtggc cggtacggcc
    19741 tccgcggatg gcgacggacc gaaaaccatc aggccggcgg cgacggccag cgccgcgacc
    19801 ccggatgcca gcactttcga taagcggaac atgttcttcc ttacctgtgg ggaaatccga
    19861 actgcttgag agcgctctca gagtccggct ccggtcatct cctgtcaatg aacctgacag
    19921 agctcggaga acccgatcga cctcggtagg ctcggtgcgg cgttcgggca agggcagggc
    19981 gcaactgccg tcaacagggg atgagtcgac atgagcggtg caccgtcttt ggagcccttc
    20041 cggcccttgg ggaacgacga cccgcccgtt gtgggcgggt accgcctggc ggcggtcctg
    20101 ggcgcgggcg gcatgggcaa ggtgtacctg tcgttcacac ctggcgggcg gcccgtcgcg
    20161 ctgaaggtga tccgccccga attcagtgag gatccggagt tccggcgccg gttccagcag
    20221 gaagtgcgat ccgcccagcg ggtgcagggc ctgtacacgg caccggtcat cgacttcgac
    20281 accgacggtg cgcagccgtg gcttgccacc gcctacgtac ccgggccctc gctcgccgag
    20341 gcggtgtcga cgtacggcgc gctgccgctg cgcagcgtgc tcctgctgac cgtcggagcc
    20401 gccgaagccc tgcacgtcat ccacgccgcg ggcatcgtgc accgcgacct gaaacccgcg
    20461 aacgtcctgc tcgccgcgga cggcccgcgc gtcatcgact tcggcatcgc ccgcgccgcc
    20521 gacaccacgg ccctcaccgg caccggcgtc agcgtgggca cgccggcgtt catggcgccc
    20581 gaacaggcgg cgggcgctgc cgtgacgccc gccaccgaca tcttcgccct cggccagatc
    20641 gcggcctacg cggcgatcgg ggcgcccgcc tacggcaacg gcccctccca cgccgtgctg
    20701 taccggatcg tccacgagga ccccgacctc agccggctgc cctccgagct gcggccgctg
    20761 atcgcccggt gcctcagtcg cgagccggcc gggcggcccg ccctgaccga gatcatcgag
    20821 ctgtgtcacg gcctctcccc cgacccgctg aggcagggcg aggactggct gccgcaaaca
    20881 ctggccgggt ccctcacctc gcgccaacag ctccctgaac ccgcccgtac gccggccccc
    20941 ggcggcccga cacccaccgc gtactccccg cacgtgccgg cgcccgggtt cgggccggcg
    21001 cccgggtccg agcaggcgtc cgcgcccacg cggaccgcgc cgggcaggcc ggggacggct
    21061 ccggccggcc cgggcttccc gcccaccccg ccgcctgccg tcaccgggca gcaagcctgg
    21121 ggcccgccgc ttcccccgca gcggcggaag ggccgcggcc tgatcatcgc cggcgcggtg
    21181 gcggcggcgc tggtcgggct ggtcgtcgtc aactcgctcc tgccggacgg ctcgggcaag
    21241 gacggctcca agcagcccgc cgccggcaac tccgccgaac cgtcgggcgg gaagcggccg
    21301 gacccgcagc ccgtcgagta caagggcatc gacctgaccg agaactactt
//
