LOCUS       NZ_CP102332            20936 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Streptomyces changanensis strain HL-66 chromosome, complete genome.
ACCESSION   NZ_CP102332
VERSION     NZ_CP102332.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces changanensis
  ORGANISM  Streptomyces changanensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6817869)
  AUTHORS   Wu,H. and Han,L.
  TITLE     Streptomyces changanensis sp. nov., an actinomycete isolated from
            soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6817869)
  AUTHORS   Wu,H. and Han,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2022) College of Forestry (Academy of Forestry),
            Northwest A&F University, Northwest A&F University, Yangling,
            Shaanxi 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.9; Pilon v. 1.24
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 187.45x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024600715.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 19:18:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,071
            CDSs (total)                      :: 5,982
            Genes (coding)                    :: 5,812
            CDSs (with protein)               :: 5,812
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 170
            CDSs (without protein)            :: 170
            Pseudo Genes (ambiguous residues) :: 0 of 170
            Pseudo Genes (frameshifted)       :: 70 of 170
            Pseudo Genes (incomplete)         :: 131 of 170
            Pseudo Genes (internal stop)      :: 9 of 170
            Pseudo Genes (multiple problems)  :: 37 of 170
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:13:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6291635
            Orig. end                         :: 6312571
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102332.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20936
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="21"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20936
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20936
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10936](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10936
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    404..418
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.06"
                     /tool="antismash"
     misc_feature    complement(1277..1292)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.75"
                     /tool="antismash"
     gene            complement(1782..2759)
                     /locus_tag="NRO40_RS27565"
                     /old_locus_tag="NRO40_27565"
     CDS             complement(1782..2759)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (6-169). E-value: 5.6e-14. Score:
                     44.4. Matches aSDomain:
                     nrpspksdomains_NRO40_RS27565_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009305906.1"
                     /locus_tag="NRO40_RS27565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27565"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_058940469.1"
                     /sec_met_domain="adh_short (E-value: 6.3e-31, bitscore:
                     106.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHTKGLVVVITGASSGIGRAVALDFARRGASLVLAARGTEALQAV
                     ARECRTHRGTRAVVQPTDVSDAAAVTALARRAVAEFGRVDVWVSAAAVAVFGAVEDVPP
                     EDVRRVLDVNVVGCVNAARAALPLMRAQGAGCLVDVASVLGLTGSPYNSAYTMSKHALR
                     AFDACLRQELRLEGVRGVHVCTVLPPTVDTPFFRHVANRSGREVRAMPPVYTPERVARA
                     VRGAVRRPREEVVVGSAGHAVRLAAAVAPGPLGRALAVKVDRTHFVRGGSAPQSAGTLY
                     APPPGPGSTRDGWHGAGRTAGRRLTGVTALAAATAGAVRRTRRR"
     aSDomain        complement(2253..2741)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NRO40_RS27565_PKS_KR.1"
                     /evalue="5.60E-14"
                     /label="NRO40_RS27565_PKS_KR.1"
                     /locus_tag="NRO40_RS27565"
                     /protein_end="169"
                     /protein_start="6"
                     /score="44.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGRAVALDFARRGASLVLAARGTEALQAVARECRT
                     HRGTRAVVQPTDVSDAAAVTALARRAVAEFGRVDVWVSAAAVAVFGAVEDVPPEDVRRV
                     LDVNVVGCVNAARAALPLMRAQGAGCLVDVASVLGLTGSPYNSAYTMSKHALRAFDACL
                     "
     CDS_motif       complement(2649..2738)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NRO40_RS27565_0001"
                     /evalue="1.50E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="NRO40_RS27565"
                     /protein_end="37"
                     /protein_start="7"
                     /score="17.7"
                     /tool="antismash"
                     /translation="VVITGASSGIGRAVALDFARRGASLVLAAR"
     misc_feature    complement(2729..2743)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.26"
                     /tool="antismash"
     gene            complement(2828..4837)
                     /locus_tag="NRO40_RS27570"
                     /old_locus_tag="NRO40_27570"
     CDS             complement(2828..4837)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536192.1"
                     /locus_tag="NRO40_RS27570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27570"
                     /product="transglycosylase domain-containing protein"
                     /protein_id="WP_079046796.1"
                     /transl_table=11
                     /translation="MTRVRLDYPRRGRRGPSRFVPSWRQWLGLVLLGLTAVAGLAGWVY
                     ATTPIPDVNAEARSEATVYYWADGTQMVSVGPVNRQNVPLSDVPRPLRDAVIATENATF
                     YSDPGFSVRGLARAVVATAGGGELQGGSTITQQYVKNTYLTQERTASRKLRELCLSVKL
                     SRTLSKDEILQGYLNTSWFGRGAYGVQAAAVAYYGTDARNLDPSRGALLAALLKGGDLY
                     DPALGEAHRRRAEARWRYVLDRQVELGLMTRAERAAHTVFPEPRPRSVANGLAGQVGYL
                     VDAADKDLRNRTGLTPEALGRGGYRIRTTFDRAAVERLRRAVDDAAPATATGVTGGADG
                     GARGANGVVQFGAASVRPGDGAVLALYGGPDATRHFSNNADTAGVPAGSAFTPFVAAAA
                     LQRGLVGEETPRRALALRRALVRGDPEVFLRLGEAVGPAGVRDVAVGAGLLPRSMAPLE
                     PAFALGTSTPSAIRMAGAYATFASGGRRADPYSVTAATYRGVPVEGLERPPARQVLDPG
                     VAREVARGLRDVAVDAVDPGTLGALGPIAAGRTGTGDRSPAAWFVGYGEELSTAVTVFR
                     TRPDGGGLLPLTGGDGSGPGGPGSLESTGTEGAETETSDTGGSGGRVDGPGADGSETGG
                     SGGRAGGPAVRVWSAYMAASASAGGAGGGARDAG"
     gene            complement(5072..6004)
                     /gene="tgmB"
                     /locus_tag="NRO40_RS27575"
                     /old_locus_tag="NRO40_27575"
     CDS             complement(5072..6004)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="tgmB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058170.1"
                     /locus_tag="NRO40_RS27575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27575"
                     /product="ATP-grasp ribosomal peptide maturase"
                     /protein_id="WP_058940470.1"
                     /transl_table=11
                     /translation="MTVLVLTCEEDVTADLVVAELGALGVPLVRFDPADLPGRVALCAE
                     YARGDFRGHLSVDGRLVGTAGVRGVWVRRPGTPAARAPGASAWLTAEAGQALYGMLSST
                     AARWMNHPAAAERARIKPWQLRVAHGSGFAVPPTVVTTFPRAAEQFAARHRRVVVKTLS
                     GPPREEPGLLVPTALVGPDADFAAVAAAPTLLQRYVPRRADVRLTAVGGRLFAARKRSA
                     PGQVDGRYGDSGHGWEPVAVPERIAGAVRAYTATARLAYGAFDFAEDEDGVWWFLECNQ
                     GGQFGFVELETGLPLARTVASWLAGLDSA"
     gene            complement(6021..6218)
                     /gene="tgmA"
                     /locus_tag="NRO40_RS27580"
                     /old_locus_tag="NRO40_27580"
     CDS             complement(6021..6218)
                     /codon_start=1
                     /gene="tgmA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670659.1"
                     /locus_tag="NRO40_RS27580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27580"
                     /product="putative ATP-grasp-modified RiPP"
                     /protein_id="WP_058940471.1"
                     /transl_table=11
                     /translation="MGRPFALRYAVPAGAGAGTAPPYAYDAALQLNVLPDGRPAVADPE
                     VLRAAGTTTSTAGSQTHFDD"
     gene            complement(6359..8149)
                     /locus_tag="NRO40_RS27585"
                     /old_locus_tag="NRO40_27585"
     CDS             complement(6359..8149)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010474892.1"
                     /locus_tag="NRO40_RS27585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27585"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_058940472.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1e-42, bitscore:
                     144.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPHISAGLRRSAAAVALGAAVALAAPAAPAAAAPQAAAATPTAA
                     TAPTGAWAAGTRAYLVITTPGDTSAVRAAVAGNGGTVFAHYDAIGVVVAHSASATFATT
                     MRGVSGVQQVGATRTSDVPADAYAPALPPTPTQSATTLTESDRWDMTQIRADQAWAVTT
                     GSATVKVGVLDTGVDDLHQDIAPNFNAADSVSCAYGRADTRAGAWRDVGTHGTHVAGTI
                     AAAKNGKGVIGVAPGVRISSVRIAEPTTSMFFAENTICGFMWAGDHGFRVTNNSYYTDP
                     WMFNCPDDADQAAIIEGVRRAQAYAEGKGSLQVAAAGNSNYDLANKTTDTSSPNDSTPV
                     SRRITNACVDIPTELPGVVTVAAMGRGNVKASYSNFGRDVIDIAAPGGDGSSGVYSTLP
                     GGKYGNMNGTSMASPHVAGVAALLASVNPSFTPADLRARLASQATDTACPSDSRCTGTT
                     AKNGFFGEGQTDALKAVGGSTPTPGTYFENTADVAITDNGTVESPITVTGVSGNAPAAL
                     KVGVDVKHTYRGDLVLSLVAPDGTVYPLEDFANGDSGDDVVKTYTVNASAEVAAGTWKL
                     RVRDVATQDSGRIDAWNLTF"
     misc_feature    8244..8258
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.96"
                     /tool="antismash"
     gene            complement(8511..9428)
                     /locus_tag="NRO40_RS27590"
                     /old_locus_tag="NRO40_27590"
     CDS             complement(8511..9428)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309216.1"
                     /locus_tag="NRO40_RS27590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27590"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_058940473.1"
                     /transl_table=11
                     /translation="MSVEETWSIGELAERAGVTVKTVRYYSDLGLLPEDGRSAGGHRRY
                     GPGALDRLRLIRSLRGLDVPVADVGRVLEREGALDDVIAGHLRDVGSRMVALRWREAAL
                     RLLQESPAEERAERLCLVGSLGTPPSTAPVARFLRRVLPPRLPARLFSAISDAAVPQPP
                     AEPTPAQVLALARLNALAADGTGAVTVCRTVPGDPGGACRPAVLYEALAEVYAAAAPEL
                     RAARQPSGGAVDAFVAAHAGARGLRDTPAFRRRLTVYLDELAHPGVDRFWRLTAELAAS
                     PEPTFGATDDWLRAALAAEVTAAG"
     misc_feature    9669..9685
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.3"
                     /tool="antismash"
     misc_feature    9903..9918
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.87"
                     /tool="antismash"
     misc_feature    9903..9923
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 17.94"
                     /tool="antismash"
     misc_feature    9925..9939
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    9934..9948
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.92"
                     /tool="antismash"
     misc_feature    9934..9949
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.92"
                     /tool="antismash"
     misc_feature    complement(9936..9949)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.54"
                     /tool="antismash"
     misc_feature    complement(9937..9950)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.58"
                     /tool="antismash"
     misc_feature    9940..9953
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 11.8"
                     /tool="antismash"
     gene            10001..10936
                     /locus_tag="NRO40_RS27595"
                     /old_locus_tag="NRO40_27595"
     CDS             10001..10936
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742346.1"
                     /locus_tag="NRO40_RS27595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27595"
                     /product="terpene synthase family protein"
                     /protein_id="WP_232790946.1"
                     /sec_met_domain="T1TS (E-value: 9.8e-53, bitscore: 178.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRGLIDGAWEQFAGIGFGHLTARVDRGAPYERIVLLSEWMAWSF
                     VLDDQHDLLIREGRLDAWQPVSDAIARHVRGERSGRPGAAPHSALLDTFVELCDRILAG
                     MPPSIQDRYRVHVPRMLRSLDEEAANRRPGHRPTVEEYVLTRRHSSQLLPMMDMVEADQ
                     GIEVPAEIRRSPAFQELAWSAIDVISWGNDVFSLPKEYSCGDTNNLAALLAAWHDLTLT
                     DAVRAVEERVHARVEDFLAAARRLPGALEGFGVTDAAARTATDRCVRSYEDWMVGADLW
                     QRYDCTRYRDERFAAGLEAAYTRPDLLSAA"
     gene            10948..12378
                     /locus_tag="NRO40_RS27600"
                     /old_locus_tag="NRO40_27600"
     CDS             10948..12378
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742345.1"
                     /locus_tag="NRO40_RS27600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27600"
                     /product="cytochrome P450"
                     /protein_id="WP_232790947.1"
                     /sec_met_domain="p450 (E-value: 6e-79, bitscore: 264.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARTSHRTSSDGPERSDGPARPGPDGPGPARPGATAVAPMAPGRL
                     PVLGHALQLWRGPIAFLESLRPAGAVVRVDLGGWPLHVLTDPDLIHTVLVGEAQDYGRG
                     RIFEKLRPLFGNGIATTDGAFHRKQRRLMQPAFQRNRISRYAELMCREADAMASSWSAG
                     TEVRVDREMRRFALSAVAGMIFSGDVDQPAVREVHRSFPIILEGMLVRTVMPKAFDRLP
                     IPLNRRFDGAATRLRAIIDEVVAEYGPEDRGQDDLISLLLSSTDAETGETMSAEQVRDE
                     LITILFGGTETASTTLSWIFHELARHPDVEKRVHAEVDAVVGDRPVRPDDLAALTYTRS
                     VFEESLRLHSPLLFTRRTLTPVTLGGVAIPAGAEIAYSPYALHRDPALFRDPTTFDADR
                     WSDADPSRLPRLNSFIPFGAGQHKCIGDAFAVAEILSAVASVASRWRLAPVPGSVVKEV
                     PAGIPLPDALPMVPVPRR"
     gene            12522..14354
                     /locus_tag="NRO40_RS30655"
     CDS             12522..14354
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.5"
                     /locus_tag="NRO40_RS30655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AAA family ATPase"
                     /protein_id="WP_306674890.1"
                     /transl_table=11
                     /translation="MTTAGEQQERDTAPLLEAPLLERDSELRAIRRALDGLCGTSAAGA
                     HTTRQGGVLAFAGPAGLGKTTLLTQLRHLAAERGCTVLSARGGEQERQVPFHVMRQLIQ
                     PVFAAMAEEERRQILGDWYDIVAPATGLSAPKAGANPDPQGVRDGLDWVITNLSVRSGP
                     VVLVLDDAHWADSESLAWLTAFAVRAEELGMLIVVACRPDELPPDAVPLHTLAQRHGSR
                     SHELAPLTSGAVARIVRSALGEGADELFCRECWAITGGNPFEVVELAAKGRDRGLAPRE
                     ENIPQLRDLASAVKGSGLIERLEQLGPSAVRLAWAAAVVGTGVPTTVVGTVAALGTAQL
                     DDAVEQLQAARILTVLPSLRHERVVEFYHPLIATAVYRSIPPGVRVGMHGVAAQALVDE
                     GLGAAAAARHMLEMHPEGDPWVVQQLRHAARDSFSAGAPDAARRYLARALREPPDVEDR
                     ALVLFELGSANLPHEPATTVNQLRAALEEPKIEQELREAVTYRLAQALAHTGQMQQATE
                     LLTEEARRTTSSRTRLRMQAEQFKWNAVHVDEHDSTGRSRLLTTFAKRLTGRDLAERHI
                     LGLRAWDVVMRAEPAAHSLDYAEQALRGGMSWTD"
     gene            14397..15437
                     /locus_tag="NRO40_RS30660"
     CDS             14397..15437
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS30660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="M48 family metallopeptidase"
                     /protein_id="WP_306674891.1"
                     /transl_table=11
                     /translation="MYCDQPGRAEELFHDGIAEFEAKGWRGAHLSFAYTLLGYIRFRRG
                     RLAEAEDFVRSGLQIADRVGHGIPAQWYAVGILIETLLARGRADEAQRVAARYRFGADF
                     PKVVVYPDPQAVWGKLLLARGRTDEAVQQLTAAGRRLERRGTRNPAWSPWQLDLALALA
                     DRHPEEARKNADAAVARARAFGTASAVGQALRVAAAISEPINGVALLGEAVDHLEQSPA
                     AYELAHALIDHGTALRALGSLDLAAQQLYRGMETAVACGADSLAARARGQLAAAGLRPR
                     RPLPAERDTLTILEEAAARHAAEGLDNTAIADRMGSDEQSVSELLSAVFTKLGTDRLGL
                     CRALGH"
     gene            complement(15497..16306)
                     /locus_tag="NRO40_RS27610"
                     /old_locus_tag="NRO40_27610"
     CDS             complement(15497..16306)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005322000.1"
                     /locus_tag="NRO40_RS27610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27610"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_058940475.1"
                     /transl_table=11
                     /translation="MPPSPFSRSWTDRSRPGYKVRYAVRHPERVVPYVRRAGRDLWLRL
                     RSRGDHVAYYRGVMASDTARSPEAAVGGAPSRERWLAIGRMQFDYLVGHGLRPEDRMLE
                     IGCGNLRAGWRFIRHLEPGHYYGIDISPDILIEAKRTLVRYGLQDRMPYLTPVDDLTLD
                     FLPDAHFTVVHAHSVFSHSPLEVIDECLAHVGRVLAPGGFFDFTFDRTEGREHQVLRED
                     FYYRTETLVGLARKHGLRARFMDDWELLPHGQSKLRVTGPEPDPAVP"
     misc_feature    complement(16321..16336)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.15"
                     /tool="antismash"
     gene            complement(16440..17291)
                     /locus_tag="NRO40_RS27615"
                     /old_locus_tag="NRO40_27615"
     CDS             complement(16440..17291)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603138.1"
                     /locus_tag="NRO40_RS27615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27615"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_058940476.1"
                     /transl_table=11
                     /translation="MPSHIPHTDRPDLKADCANCFGLCCVALPFARSADFAADKPAGTP
                     CGNLRDDFRCGIHTRLRESGYTGCTVFDCLGAGQKVSQVTFGGRDWRAEPDTARTMFAV
                     FPVVRQLHELLRYAAEALDLPAARPVHPELSRLHDRIDALSRGGADELSALDVGALRAE
                     VNVLLLRAGELARAEVPGRRRDHRGADLMGARLRGARLRGASLRGAYLIAADLTGADLR
                     RADFIGADLRDADLSGADLTGALFLTQAQLNAARGDGATRIPDALTRPAHWTARPGRAA
                     RR"
     gene            17480..18367
                     /locus_tag="NRO40_RS27620"
                     /old_locus_tag="NRO40_27620"
     CDS             17480..18367
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025774.5"
                     /locus_tag="NRO40_RS27620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27620"
                     /product="MEDS domain-containing protein"
                     /protein_id="WP_157901781.1"
                     /transl_table=11
                     /translation="MSDVGVIAGEERHPGTLPVQHMGAGDHAFLCYDRETPGWDVLTAF
                     VWAGLARGEKVIVFGPPHLSETQLRTRLRDAPGPLVATGFESAQLEMSSMRELILPAPR
                     FTADRQWQRITEEVGAARAEGYRGLRTYIDMGWVADLGADLDLMVDRERRAGHLFADGF
                     YSEVCAYERDRFPAPVLEAMCRAHPRNLLPALGRLRCPYGEGVLRVIGDADSATYDCFR
                     RAVDGALRGLPRGRPATVDLRRTGYLGPECAAELVRALTGPPALRSVRVRCSPGHALLL
                     RRLGADPAVLDTTG"
     gene            18372..18815
                     /locus_tag="NRO40_RS27625"
                     /old_locus_tag="NRO40_27625"
     CDS             18372..18815
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090825.1"
                     /locus_tag="NRO40_RS27625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27625"
                     /product="ATP-binding protein"
                     /protein_id="WP_058940478.1"
                     /transl_table=11
                     /translation="MALETAGTVPGNGEGADILLRCPFGGSDIPRLRVLVESHAAQAGL
                     PEPRRGDFVVAVDAVVVNAVRHAGGSGVLVLARTARELECRVSDRGPGFTEDVIPELAP
                     GIGGACPGRGLWLTRLITDRLTVTPGPAGGSTVTFAMRLGDGR"
     gene            complement(18928..19524)
                     /locus_tag="NRO40_RS27630"
                     /old_locus_tag="NRO40_27630"
     CDS             complement(18928..19524)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445341.1"
                     /locus_tag="NRO40_RS27630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27630"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_058940479.1"
                     /transl_table=11
                     /translation="MPGCDTAPGGQEPAPVKILVAGGFGVGKTTLVEAVSEIEPLRTEE
                     RLTAAGVGVDDLDGIEAKSATTVAMDFGRITLDDAGVVLYLFGTPGQERFWFLWDDLLH
                     GALGAIVLVDTRRLDRGFPAVDFFESRGLPFVVGANCFHGRQPYTAGEIRAALRLRDPE
                     TPVLLLDARVRDEVRATLLSLLDTVIDRARSAAPS"
     gene            complement(19511..19876)
                     /locus_tag="NRO40_RS27635"
                     /old_locus_tag="NRO40_27635"
     CDS             complement(19511..19876)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007261963.1"
                     /locus_tag="NRO40_RS27635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27635"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_058940480.1"
                     /transl_table=11
                     /translation="MPDEPHRRGGRRPRLYAVTDGRTAAPRTALTMDTTITAAVGGDAP
                     DGLPTEWRHVLALCPAPTGRAVAEIAARMGMRLTPMTLLLGELADRGLVHHRPPLEAAA
                     TTDVHLLMRIRDNLARM"
     gene            complement(19876..20289)
                     /locus_tag="NRO40_RS27640"
                     /old_locus_tag="NRO40_27640"
     CDS             complement(19876..20289)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018386278.1"
                     /locus_tag="NRO40_RS27640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_27640"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_058940481.1"
                     /transl_table=11
                     /translation="MTTTNDMIYSVLDNNLSRIAGIEGAVLLSNDGIMLSAYLLDRAQA
                     ERIAAASSGVAATMRAISRDVDGGRVIRQLVEMDERYLCLVGCGEGSTLVVVTNRKARL
                     GELGGEAVRTAQALGEWLGTPDRAQPPSSPPAP"
ORIGIN
        1 cccgacgccg tcgtcatcgg agccgggccc aacgggcttg tcgccgccaa cctcctggcc
       61 gaccggggct ggacggtcga cgtcctggaa gcccaggacg cgcccggcgg cgccgtccgc
      121 agcgaccgcg gcgtccaccc cgaccacgtc aacgacctgt tcagctcctt ctacccgctc
      181 gccgccgcct ccccggtcat ccggggcctg cggctgcacg agtacgggct gacctggagc
      241 cacgcaccgg ccgtcgtcgc ccacccgctc acggacgggc gctgcgccgt gctggaacgc
      301 gacccggacc gcaccgccga ggacttggag cgcttcgccc ccggtgacgg cgacgcctgg
      361 cgggagctgt gcgcgctgtg ggaccgggtg ggcggcgacg cgctggacgc cctgttcacc
      421 cccttcccgc ccgtgcggtc cggactgcgc ctcgccgccc ggctgcgcgg tcctgacggg
      481 ctgcgcctgc tgcgcaccgc cctgctgccc gcgcggcgca tgggcgagga gacgttcgcc
      541 ggggacggcg ggcggctgct gctcgcgggg aacgccctgc acgccgacct gtccccggag
      601 acggcgctcg gcggcggctt cggctggctc atgtgcatgc tcggccagac ggtgggcttc
      661 cccgtcccca ccggcggcgc gggcgccctc accgacgccc tggtccgccg cctggccgac
      721 cgcggcgtga ccgtgcggtg cggacggcac gtcaccgaag tcgtcgtccg cgacgggcgg
      781 gcccacggcg tgcgcaccgc cgacggcgag accgtcacgg cacgccgggc cgtcctcgcc
      841 gacgtgcccg cgcccgccct ctacggcgag ctcgtcgcct gggagcacct gccggaccgc
      901 gtccgcgacg acatgcgccg cttccagtgg gacttcgcga cggtgaaggt cgactgggcc
      961 ctggaccggc ccgtgccctg ggccaccgaa gggcccggac gcgccgggac ggtccacctc
     1021 gccgacggcg tcgacgaact gacccgcttc gccgcgcaga tcgccatggg cctcgtcccc
     1081 gaccggccgt tcctcatctt cggccagatg accacggccg acccctcccg ctcgcccgcc
     1141 ggtaccgagt cggcctgggc gtacacccac gtgccccgca ccatcaccgg cgacgcgggg
     1201 cccgacggga tcaccggcgc ctggacaccc gacgacggac agcgcatggc ggaccggatc
     1261 gaggcggtcg tggagcggtt cgcgcccggc ttccgcggca cggtacgggc ccgccgggtg
     1321 ctcaccccgc tcaccctgga ggccctggac gccaacctgc gcgggggcgc cgtcaacggt
     1381 ggcacgaccg cgctccacca gcagctggtg ttccgccctg tccccggcac cggccgtccc
     1441 gagacccccg tgcggggcct gtacctcgcc tccgcctccg cccacccggg cggaggcgtg
     1501 cacggcgcgc cgggcgcgaa cgcggcgcgg gccgccttgc acgcgagcgg cgcgccgttc
     1561 gcgaccctgc tgtcggcggg acaacgcctc ctgacgggcc gcggcggaac acctgacggg
     1621 ccgcggccca acgcctgacc ggccgcggcg gacgccgcac gcgggccgcg gccccggccg
     1681 tggggcgccc gtgaacgacc cgcccgagga cggaccgcgc ctcccgccgg cccgtccgcg
     1741 cctgcggcgg tgggccgcgc gcccaccgcc gtggaccgcg cctaccgccg ccgcgtccgg
     1801 cggacggccc cggcggtcgc cgcggccagt gcggtcaccc cggtgagccg ccgccccgcg
     1861 gtgcgtcccg cgccgtgcca gccgtcccgc gtggagccgg gcccgggcgg cggcgcgtac
     1921 agggtgcccg cgctctgcgg ggcgctccca ccgcgtacga agtgggtccg gtccaccttg
     1981 acggcgaggg cccgccccag cgggccgggc gcgaccgcgg cggccagccg caccgcgtgt
     2041 cccgccgagc ccacgaccac ctcctcccgt ggcctgcgca cggcgccccg gaccgcccgg
     2101 gcgacccgtt ccggcgtgta caccggcggc atcgcgcgca cctcgcggcc gctgcggttg
     2161 gccacgtgcc ggaagaacgg cgtgtcgacg gtcggcggca gcacggtgca cacgtgcacg
     2221 ccccgcacgc cctccaagcg cagttcctgc cgcaggcagg catcgaacgc ccgcagcgcg
     2281 tgcttcgaca tcgtgtacgc gctgttgtac ggcgaacccg tcaggcccag taccgacgcc
     2341 acgtcgacca ggcagccggc gccctgcgcc cgcatgagcg gcagcgcggc gcgcgccgcg
     2401 ttcacgcacc cgacgacgtt cacgtccagg acccggcgca cgtcctcggg cggtacgtcc
     2461 tccacggcgc cgaagacggc gaccgcggcg gcgctcaccc acacgtcgac gcgcccgaac
     2521 tcggcgaccg cgcgccgggc gagcgccgtc acggccgccg cgtcggacac gtccgtcggc
     2581 tggaccaccg cgcgcgtccc ccggtgcgta cgacactccc gcgcgaccgc ctgcagcgcc
     2641 tccgttcccc gcgcggccag cacgagcgag gcgccccgcc gggcgaagtc cagggcgacc
     2701 gcgcggccga tgccgctgga cgccccggtg atcacgacga ccagtccctt ggtgtgcacg
     2761 cgtacctccc gtgccggctc tcgacggtcc tggccagtcc cggagtaccc gcgcccgtcc
     2821 gccccactca ccccgcgtcc cgcgccccgc ccccggcccc gccggccgac gcgctcgcgg
     2881 ccatgtacgc cgaccacacc cgcaccgcgg gcccgcccgc acgcccgccg gaaccgcccg
     2941 tctcggaacc gtccgcaccc ggcccgtcca cacgcccgcc ggaaccgccc gtgtcggaag
     3001 tctccgtttc cgcgccctcc gtaccggtgc tctccaggga ccccggcccc ccggggccgg
     3061 aaccgtcccc tccggtcagc gggagcaggc ccccgccgtc cgggcgggtg cggaagacgg
     3121 tgaccgccgt cgacagctcc tcgccgtaac cgacgaacca cgccgcgggc gaccggtccc
     3181 cggtccccgt gcggcccgcc gcgatcggcc cgagggcgcc cagcgtgccc gggtccaccg
     3241 cgtccaccgc cacgtcacgc agtccgcgcg ccacctcccg cgcgacgccc gggtcgagca
     3301 cctgccgggc gggcggccgc tccagaccct ccacaggaac gccccggtac gtcgccgcgg
     3361 tcaccgagta cgggtcggcg cgccgcccgc cggaggcgaa cgtggcgtac gccccggcca
     3421 tccggatcgc gctcggcgtg gacgtgccga gcgcgaacgc cggctccagc ggcgccatgc
     3481 tgcgcggcag caggcccgcg ccgaccgcga cgtcccgcac cccggccggc ccgaccgcct
     3541 ccccgagccg caggaacacc tccgggtcac cccggaccag cgcccggcgc agcgcgaggg
     3601 cccggcgcgg cgtttcctcg cccaccaggc cccgctgcag ggcggccgcc gcgacgaacg
     3661 gcgtgaaggc ggatccggcg gggacgcccg ccgtgtcggc gttgttggag aagtgccggg
     3721 tcgcgtccgg gcccccgtac agcgccagca ccgccccgtc acccggtcgc accgacgccg
     3781 cgccgaactg caccacaccg ttcgcccccc gcgccccgcc gtccgcgcca cccgtcaccc
     3841 ccgtggccgt ggccggggcc gcgtcgtcga cggcccgccg cagccgctcc accgccgccc
     3901 ggtcgaaggt cgtgcggatc cggtacccgc cgcgcccgag cgcctcgggg gtgagccccg
     3961 tccggttgcg caggtccttg tcggccgcgt cgaccaggta accgacctgg cccgccaggc
     4021 cgttcgccac cgacctgggc cgcggctcgg ggaacacggt gtgggcggcc cgctccgcgc
     4081 gcgtcatcag cccgagctcc acctgacggt ccagcacgta ccgccaccgc gcctccgccc
     4141 gccgccggtg tgcctcgccc agcgccgggt cgtacaggtc accgcccttc agcagcgcgg
     4201 cgagcagggc gccgcgggag gggtcgaggt tccgcgcgtc ggtgccgtag taggccacgg
     4261 cggcggcctg cacgccgtac gcgccgcgcc cgaaccagct ggtgttgagg tacccctgga
     4321 ggatctcgtc cttggacagg gtccgcgaca gcttcaccga caggcacagt tcgcgcagct
     4381 tccgggacgc cgtccgctcc tgcgtgaggt acgtgttctt cacgtactgc tgggtgatcg
     4441 tcgacccgcc ctgcagttcg ccgcccccgg ccgtggcgac gacggcgcgg gccaggccgc
     4501 gcacggagaa gccggggtcg ctgtagaagg tcgcgttctc cgtggcgatg acggcgtcgc
     4561 gcagcggtcg cgggacgtcg gacagcggga cgttctgccg gttgaccggc ccgacgctca
     4621 ccatctgagt gccgtccgcc cagtagtaga cggtggcctc ggaccgcgcc tcggcgttga
     4681 cgtcggggat cggggtcgtc gcgtacaccc acccggccag cccggctacc gccgtcaggc
     4741 ccagcagcac gaggcccagc cactgccgcc acgacggcac gaaccgtgaa gggccgcggc
     4801 gcccccggcg cgggtagtcg agacggacgc gtgtcacggt gggggcctcc tcggtgcggt
     4861 ggagcggctg cgtcctctcc tacggggtgc gccggccgcc cgttcaccgg cgcccgccga
     4921 tccgagccgc ccgcccgttc accggcgccc gccgaccccg gccggccgcc ggcagtcccc
     4981 gcaccggccc ccacatcggc cggccggccg cccgtcctcc gcgccggtgc cgaccccgcg
     5041 cgaggcggcc ggccgcccgt acgggcgcgg ttcacgccga gtccaggccg gccagccacg
     5101 acgcgacggt ccgtgccagg ggcagtcccg tctccagctc cacgaagccg aactggccac
     5161 cctgattgca ctccaggaac caccacacgc cgtcctcgtc ctcggcgaag tcgaaggccc
     5221 cgtaggcgag ccgggccgtc gccgtgtacg cgcgcacggc gcccgcgatg cgctccggca
     5281 ccgccacggg ctcccagccg tggccgctgt cgccgtaccg cccgtccacc tggccgggcg
     5341 ccgaccgctt gcgcgcggcg aacagccgcc cgcccaccgc ggtcagccgc acgtcggccc
     5401 gccgggggac gtaccgctgg agcagggtcg gcgcggcggc gacggcggcg aagtccgcgt
     5461 ccggccccac cagcgcggtc ggcacgagca gtcccggctc ctcgcgcggc ggcccggaca
     5521 gggtcttcac caccacccgc cggtgacggg cggcgaactg ctcggccgcc cgggggaacg
     5581 tcgtcaccac ggtcgggggc acggcgaaac cgctcccgtg cgccacccgc agctgccacg
     5641 gcttgatccg ggcccgctcg gccgcggccg ggtggttcat ccagcgggcg gccgtggacg
     5701 acagcatccc gtacagggcc tggccggcct cggcggtgag ccaggcggac gcccccggcg
     5761 cccgcgcggc gggcgtgccc ggtctgcgca cccacacgcc gcgcaccccc gccgtgccga
     5821 ccaggcgccc gtccaccgac aggtggccgc ggaagtcgcc gcgcgcgtac tcggcgcaga
     5881 gcgcgacccg gcccggcagg tcggcggggt cgaaccgcac caaggggacg cccagagcgc
     5941 ccagttcggc gaccacgagg tccgccgtga cgtcctcctc gcacgtcagc accagtaccg
     6001 tcatcgcgga cgccggccgg tcagtcgtcg aagtgcgtct gggagccggc cgtcgacgtc
     6061 gtcgtgccgg cagcccgcag cacctccggg tcggccacgg cgggccgtcc gtcgggcagg
     6121 acgttcagtt ggagcgcggc gtcgtacgcg tacggcgggg cggtgccggc cccggctccg
     6181 gccggcacgg cgtaccgcag ggcgaacggt cgtcccatgg cttcttcccg atcccttcgt
     6241 cgaccaccgg tgggtaccgg tgagtacggg ccgggggcgt gggaagctca ccacgatccg
     6301 tgacaccggc cccgccggat gcggcggggc cggtgtcacg ggcgttgcgc ggaaccggtc
     6361 agaacgtgag gttccaggcg tcgatccggc cggagtcctg cgtggcgacg tcgcgcacgc
     6421 gcagcttcca cgtaccggcg gcgacctccg ccgaggcgtt cacggtgtac gtcttgacga
     6481 cgtcgtcgcc gctgtcgccg ttcgcgaagt cctccagcgg gtacaccgtg ccgtccgggg
     6541 cgaccagcga caggacgagg tcgccgcggt aggtgtgctt gacgtccacg ccgaccttga
     6601 gggcggccgg ggcgttgccg ctcacgccgg tgacggtgat cgggctctcc accgtgccgt
     6661 tgtcggtgat cgcgacgtcg gcggtgttct cgaagtacgt gcccggtgtc ggcgtcgaac
     6721 cgccgacggc cttcagcgcg tcggtctggc cctcgccgaa gaagccgttc ttcgcggtcg
     6781 tgcccgtgca ccggctgtcg gacgggcagg cggtgtcggt cgcctgcgag gcgaggcggg
     6841 cccggaggtc ggccggggtg aacgacgggt tcacgctggc cagcagcgcg gcgacgccgg
     6901 ccacgtgcgg ggaggccatc gacgtgccgt tcatgttgcc gtacttgccg ccgggcagcg
     6961 tggagtagac gccgctggag ccgtcgccgc ccggcgcggc gatgtcgatg acgtcacggc
     7021 cgaagttcga gtacgaggcc ttcacgttgc cgcggcccat ggcggcgacg gtcacgacgc
     7081 ccggcagttc ggtggggatg tcgacgcagg cgttggtgat cctgcggctc accggggtcg
     7141 agtcgttggg gctcgacgtg tcggtggtct tgttggcgag gtcgtagttc gagttgcccg
     7201 ccgcggcgac ctggagggag cccttgccct cggcgtacgc ctgtgcgcgc cggacgccct
     7261 cgatgatggc ggcctggtcg gcgtcgtccg ggcagttgaa catccacggg tcggtgtagt
     7321 agctgttgtt cgtgacccgg aagccgtggt cgcccgccca catgaagccg cagatggtgt
     7381 tctcggcgaa gaacatcgac gtcgtgggct ccgcgatgcg gacggaggag atccgcacac
     7441 ccggcgcgac gccgatgacg cccttgccgt tcttcgcggc ggcgatggtg cccgccacgt
     7501 gcgtgccgtg ggtgccgacg tcgcgccacg cgccggcccg cgtgtccgcc cggccgtagg
     7561 cgcaggagac cgagtcggcg gcgttgaagt tcggggcgat gtcctggtgc aggtcgtcga
     7621 cgccggtgtc caggacgccg accttcacgg tggcggagcc ggtggtgacg gcccacgcct
     7681 ggtcggccct gatctgggtc atgtcccagc ggtccgactc ggtgagcgtc gtcgcgctct
     7741 gcgtgggggt gggcggcagg gccggcgcgt acgcgtcggc gggcacgtcc gacgtgcggg
     7801 tcgcgccgac ctgctggacg ccgctgacgc cgcgcatcgt cgtggcgaac gtcgcggagg
     7861 cggagtgcgc gacgacgacg ccgatggcgt cgtagtgcgc gaagaccgtg ccgccgttgc
     7921 cggcgacggc ggcgcgcacc gcggaggtgt cgccgggcgt ggtgatcacc aggtaggcgc
     7981 gggttcccgc ggcccaggcg ccggtgggcg ccgtcgcggc ggtcggcgtg gccgccgcgg
     8041 cctgcggagc ggcggcggcg ggggccgcgg gtgccgcgag ggcgacggcc gcgccgaggg
     8101 cgacggcggc ggccgagcgt ctgagcccgg cggatatgtg gggaagcatg tgtcctccga
     8161 aggcccggcg acacgggagg cgtcgggcgg gccgggatga agaagtggtc gagccgcaag
     8221 atctcagatg tgagcacgtc aagggaagta ccgtttcgcc accggttgtt cgccctccgg
     8281 acggacatag gcggcccaag tgcggcaaag aggggccgaa tcggcacgcg gtctcaccac
     8341 acggcacccc caccgcggcg gcggcagccc ccgtcgaggg gtacgggcac gtcctcgccg
     8401 gctccccgcc gccccgtcgg ccccaccgcg cctcacggac cgcccgcccc cgccggccac
     8461 ccgccccgcc gctcgccccc gccgacgacc tgccgtcggg ccgggccgcc tcagccggcc
     8521 gccgtcacct cggccgccag cgccgcccgc agccagtcgt cggtggcgcc gaacgtcggc
     8581 tcgggcgacg cggccagctc cgcggtcagc cgccagaagc ggtcgacgcc cgggtgcgcg
     8641 agctcgtcga ggtagacggt gaggcgccgc cggaacgcgg gcgtgtcacg gaggccgcgc
     8701 gccccggcgt gggccgccac gaaggcgtcg accgccccgc cggacggctg ccgcgccgcc
     8761 cgcagttcgg gcgccgccgc cgcgtacacc tcggcgaggg cctcgtacag cacggcgggc
     8821 cggcaggcgc cgccgggatc acccggcacc gtccggcaga cggtgaccgc gcccgtcccg
     8881 tccgccgcga gggcgttgag ccgcgcgagg gccagtacct gggcgggcgt cggttccgcg
     8941 ggcggctgcg ggaccgccgc gtcggagatg gccgagaaca gtcgcgcggg cagccgcggc
     9001 gggaggaccc gtcggaggaa tcgcgccacc ggtgccgtgc tgggcggggt gcccaacgaa
     9061 cccaccaggc acagccgttc ggcccgttcc tcggccgggc tctcctggag cagccgcagc
     9121 gccgcctccc gccagcgcag cgccaccatg cgggagccca cgtcccgcag gtgccccgcg
     9181 atgacgtcgt ccagcgcgcc ctcccgctcc aggacccggc cgacgtccgc gaccggcacg
     9241 tcgagaccgc gcagcgagcg gatcagacgc agcctgtcga gggccccggg cccgtaccgc
     9301 cggtggccgc ccgcgctgcg accgtcctcc ggcagcaggc cgaggtccga gtagtagcgc
     9361 acggtcttca cggtgacgcc cgcccgctcg gcgagctcgc cgatgctcca cgtctcctcg
     9421 acggacatct gcggacctcc tgacccgggg cgccggtggt ccctcaccgt accggggcgg
     9481 gtcgtcacgc caccggcgta ccggggcgcc cccccggcgg ccgggccgcg ggccgcgccg
     9541 ggtgtgccgg gcgccgggcc ggtccccgca cccctggaat cgccaccgaa cggtcgaaat
     9601 atcgcgcctg catatgcctt tccgattacg cgccccgcat ttgctcatag cacacttcgg
     9661 gccccgggtg ggattatatt gacagtgcag ttagcggtac gggttaatgg aggcgaatgg
     9721 cttcaaagcg cggctcgtcg ttctcgcgcg agggggaatc gagccgctcc actaccggag
     9781 tcggcgaggt tgccacggtg ttgtgacagc ccggccgcga gctcgaatcc ggtcgcgggc
     9841 cgcacggcac gtgcgcggag aatggtggac cgggatttcc ttcggaggga catcgatgcc
     9901 ccatctcgac tctttcacga ttccggaatt tcatcttcca tttgaaaact cgaaggaccc
     9961 ggcggcagac cgcgccaacg cagaggctac cgcctgggcc gtggaccggg ggctgatcga
    10021 cggtgcctgg gaacagttcg ccggcatcgg cttcgggcac ctgacggcgc gggtcgaccg
    10081 cggcgcgccg tacgagcgca tcgtgctgct ctccgagtgg atggcctggt cgttcgtcct
    10141 cgacgaccag cacgacctgc tcatcaggga gggtcgcctc gacgcctggc agccggtctc
    10201 cgacgcgatc gcccgccatg tgcggggcga gcgttcgggc cggccgggcg cggccccgca
    10261 cagcgcgctg ctcgacacct tcgtcgagct ctgcgaccgg atcctggccg gtatgccccc
    10321 ctcgatccag gaccgctacc gggtccacgt gccgcgcatg ctgcgctccc tggacgagga
    10381 ggcggccaac cggcgccccg gccaccggcc caccgtcgag gagtacgtcc tcacccgccg
    10441 gcacagctcc caactcctgc cgatgatgga catggtcgag gccgaccagg gcatcgaggt
    10501 ccccgccgag atccgccgga gccccgcctt ccaggagctc gcctggagcg ccatcgacgt
    10561 catctcctgg ggcaacgacg tgttctcgct gcccaaggag tactcctgcg gggacaccaa
    10621 caacctcgcc gccctgctgg ccgcctggca cgacctgacc ctcaccgacg ccgtacgggc
    10681 cgtggaggag cgcgtccacg cccgtgtcga ggacttcctc gccgccgccc ggcgcctgcc
    10741 cggcgcgctg gaggggttcg gcgtgaccga cgccgccgcg cgcacggcca ccgaccgctg
    10801 cgtccgcagc tacgaggact ggatggtcgg cgccgacctc tggcagcgtt acgactgcac
    10861 gcgctaccgg gacgagcggt tcgccgccgg gctcgaagcc gcgtacaccc gaccggacct
    10921 gctctccgcg gcatgagggg aaagcccgtg gcccgtacca gccaccgcac gtccagcgac
    10981 ggacccgagc ggtccgacgg cccggcccga cccggccccg acgggccggg gcccgcccgg
    11041 ccgggcgcca ccgccgtcgc ccccatggcg cccggacggc tgcccgtcct cggccacgcc
    11101 ctccaactgt ggcgcggccc catcgccttc ctcgaatcgc tgcgccccgc cggggccgtc
    11161 gtccgcgtcg acctcggcgg ctggcccctg cacgtcctca cggaccccga cctcatccac
    11221 accgtcctcg tcggcgaggc gcaggactac gggcgcggcc ggatcttcga gaagctccgc
    11281 cccctcttcg gcaacggcat cgccaccacc gacggggcgt tccaccgcaa gcaacgccgg
    11341 ctcatgcagc cggcgttcca acgcaaccgc atcagccggt acgcggagct gatgtgccgc
    11401 gaggcggacg ccatggcctc ctcctggtcc gcgggcacgg aggtccgcgt cgaccgcgag
    11461 atgcgccggt tcgcgctctc cgccgtcgcc ggcatgatct tctccgggga cgtcgaccag
    11521 cccgccgtgc gggaggtgca ccggtcgttc ccgatcatcc tggagggcat gctcgtccgc
    11581 acggtcatgc ccaaggcgtt cgaccggctc cccatccccc tcaaccggcg cttcgacggg
    11641 gccgccaccc gcctgcgcgc catcatcgac gaggtcgtcg ccgagtacgg tcccgaggac
    11701 cgcggccaag acgacctcat ctcgctgctg ctctccagca ccgacgccga gacgggcgag
    11761 acgatgagcg ccgagcaggt gcgcgacgaa ctcatcacca tcctgttcgg cggcaccgag
    11821 acggcctcca ccaccctgtc gtggatcttc cacgaactgg cccgccaccc cgacgtggag
    11881 aagcgcgtcc acgccgaggt cgacgccgtc gtcggtgacc gccccgtgcg ccccgacgac
    11941 ctcgccgccc tgacgtacac ccggagcgtc ttcgaggagt cgctgcggct ccactcgccg
    12001 ctgctcttca cccgccgcac gctcaccccg gtcaccctcg gcggcgtggc catccccgcc
    12061 ggggccgaga tcgcgtacag cccctacgcg ctccaccgcg accccgcgct gttccgcgac
    12121 ccgaccacgt tcgacgccga ccgctggagc gacgccgacc cctcgcggct gccgcgcctc
    12181 aacagcttca tccccttcgg cgcgggccag cacaagtgca tcggcgacgc cttcgccgtc
    12241 gcggagatcc tcagcgcggt cgcgagcgtg gcctcgcggt ggcgtctggc cccggtcccc
    12301 ggcagcgtcg tgaaggaggt ccccgccggc atccccctgc ccgacgcgct ccccatggtg
    12361 cccgtaccgc ggcgctgacg cgccctccct gagcaagggt cagcggagaa tacaccgccg
    12421 accccgatcg agtggcgatg ttccggaaag aagggccatc ggccgtaaca acccgtcgcc
    12481 ttgcccttac actcggccgc acgtgctgga gggggcaagt gatgacaacg gccggagaac
    12541 agcaggaacg ggacaccgcg ccgctcctgg aagcgccact gctggagcgg gattcggagc
    12601 tccgcgcgat ccggcgtgcg ctggacggtc tgtgcggcac gtcggccgcc ggggcgcaca
    12661 ccacgcggca gggcggcgtc ctcgcgttcg ccgggccggc gggactcggg aagaccacgc
    12721 tcctcaccca gctccgccac ctcgccgccg aacgcggctg cacggtgctg tcggcgcgcg
    12781 gcggcgagca ggagcggcag gtgccgttcc acgtgatgcg ccagctgatc cagccggtct
    12841 tcgccgccat ggcggaggag gagcggcgcc agatcctcgg cgactggtac gacatcgtgg
    12901 cgcccgccac cggtctgtcc gcgccgaagg ccggcgccaa ccccgacccg cagggcgtcc
    12961 gcgacggact ggactgggtg atcaccaacc tctccgtccg cagcggcccc gtcgtcctcg
    13021 tcctcgacga cgcgcactgg gccgactccg agtcgctggc ctggctcacc gccttcgccg
    13081 tccgcgcgga ggagctgggc atgctcatcg tcgtcgcctg ccgccccgac gagctgccgc
    13141 ccgacgccgt ccccctgcac accctcgccc agcgccacgg ctcccgctcg cacgaactgg
    13201 ccccgctcac ctccggcgcg gtggcgcgga tcgtccgctc cgccctcggg gagggcgcgg
    13261 acgagctgtt ctgccgcgag tgctgggcga tcaccggcgg gaaccccttc gaggtcgtcg
    13321 agctcgccgc gaagggccgc gaccgcggcc tcgcgccgcg ggaggagaac atcccccagc
    13381 tccgcgacct cgcctcggcc gtcaagggca gcgggctcat agaacggctc gaacagctcg
    13441 gcccgtccgc cgtccggctc gcctgggccg ccgcggtcgt cggcaccggc gtgccgacca
    13501 ccgtcgtcgg taccgtcgcc gcgctcggca cggcccagct ggacgacgcc gtcgagcagc
    13561 tccaggcggc ccgcatcctg accgtgctgc cgagcctgcg ccacgagcgg gtcgtggagt
    13621 tctaccaccc gctcatcgcc accgccgtgt accggtcgat tccgccgggc gtccgcgtcg
    13681 gcatgcacgg cgtcgccgca caggccctcg tcgacgaggg gctcggcgcc gcggcagccg
    13741 cccgccacat gctggagatg caccccgagg gtgacccgtg ggtggtccag cagctgcgcc
    13801 acgccgcccg cgacagcttc tccgccggcg cgcccgacgc cgcacgccgc tacctcgccc
    13861 gcgcgctgcg cgaaccgccg gacgtcgagg accgcgccct ggtcctgttc gagctcggct
    13921 ccgccaacct cccgcacgag ccggccacca ccgtcaacca gctgcgcgcc gcgctggagg
    13981 aacccaagat cgagcaggag ctgcgcgagg ccgtcaccta ccggctcgcc caggccctcg
    14041 cccacacggg tcagatgcag caggccaccg aactcctcac cgaggaggcc cgccgcacca
    14101 ccagctcccg cacccgactg cgcatgcagg ccgagcagtt caagtggaac gccgtgcacg
    14161 tcgacgaaca cgactcgacg ggccgctccc gcctgctgac cacgttcgcc aagcgcctca
    14221 ccggacgcga cctcgccgag cggcacatcc tcggcctgcg cgcctgggac gtcgtgatgc
    14281 gcgccgagcc cgcggcccat tccctggact acgccgagca ggcgctgcgc ggcggcatga
    14341 gctggaccga ttaggacttc gggttcgagg taccggccgt cgtcgcgctc accctgatgt
    14401 actgcgacca gcccggccgc gccgaggagc tcttccacga cggcatcgcc gagttcgagg
    14461 cgaagggctg gcgcggcgcc cacctctcct tcgcctacac cctgctcggc tacatccgct
    14521 tccggcgcgg ccggctcgcg gaggccgagg acttcgtccg cagcggtctg cagatcgccg
    14581 accgcgtcgg gcacggcatc cccgcgcagt ggtacgccgt cggcatcctc atcgagacgc
    14641 tcctcgcccg gggccgcgcc gacgaggccc agcgggtcgc cgcccggtac cgcttcggcg
    14701 ccgacttccc caaggtcgtg gtctatcccg atccgcaggc cgtctggggc aagctgctgc
    14761 tggcccgcgg caggaccgac gaggccgtcc agcaactcac cgcagccggc cggcgactgg
    14821 agcggcgagg cacccgcaac cccgcgtgga gcccctggca gctcgacctg gccctcgccc
    14881 tcgccgaccg ccacccggag gaggcccgga agaacgccga cgcggcggtg gcccgcgccc
    14941 gcgcgttcgg cacggccagc gccgtcggtc aggccctgcg cgtcgccgcg gcgatcagcg
    15001 agccgatcaa cggcgtcgcc ctcctgggcg aggccgtcga ccacctcgaa cagtcgccgg
    15061 cggcgtacga gctggcgcac gccctcatcg accacggcac cgcgctgcgc gccctcggca
    15121 gcctcgacct cgccgcccag cagctctacc gcggcatgga gaccgccgtc gcctgcggcg
    15181 cggactcgct cgccgcccgg gcccgcggcc agctcgccgc ggccggactg aggccccggc
    15241 gtccgctccc cgccgaacgc gacaccctca cgatcctgga ggaggccgcc gcccggcacg
    15301 ccgccgaggg tctggacaac accgccatag ccgaccggat gggcagcgac gaacagtccg
    15361 tctcggagct gctgtcggcc gtgttcacca agctcggcac cgaccggctc ggcctgtgcc
    15421 gcgccctcgg ccactgaccc cacccgccag gtggcggacc ggccgcccgg ggcgacaccc
    15481 cgggcggccg ggcccgtcag gggacggccg gatccggctc cgggcccgtg acgcgcagct
    15541 tcgactggcc gtgcggcagg agctcccagt cgtccatgaa ccgcgcccgc agaccgtgct
    15601 tgcgggccag gcccaccagt gtctcggtcc ggtagtagaa gtcctcccgc agcacctggt
    15661 gttccctgcc ctcggtccgg tcgaaggtga agtcgaagaa gccgcccggc gccagcaccc
    15721 gccccacgtg cgccaggcac tcgtcgatga cctccagcgg cgagtgcgag aacacgctgt
    15781 gcgcgtgcac caccgtgaag tgggcgtccg gcaggaagtc cagcgtcagg tcgtcgaccg
    15841 gcgtcaggta cggcatccgg tcctgcagcc cgtaccgcac cagcgtccgc ttcgcctcga
    15901 tcaggatgtc cggggagatg tcgatgccgt agtagtggcc cggctccagg tgccggatga
    15961 agcgccagcc cgcccggagg ttgccgcacc cgatctccag catccggtcc tcgggccgca
    16021 gtccgtgccc gaccaggtag tcgaactgca tccggccgat cgccagccac cgttcgcgcg
    16081 acggcgcccc gcccacggcc gcctccgggc tgcgggccgt gtcgctcgcc atcacccccc
    16141 ggtagtaggc gacgtgatcg ccgcggctgc gcagccgcag ccacaggtca cgcccggcgc
    16201 gccgcacgta tgggacgacc cgctccgggt gccgcaccgc gtagcgcacc ttgtacccgg
    16261 gcctcgaccg gtccgtccac gaccgcgaga acggacttgg cggcatggcg ccctcctgat
    16321 gtgtgcacgt gtggatggtt gccggtccac cgtgcacccg gtgcgggcgg ggcgcccggc
    16381 gcaccacccg tccgggcgcg acggcacccg cacggggggc gtcgactact ccgtccgtgt
    16441 caccggcggg cggcgcgccc cggccgggcc gtccagtgcg ccgggcgggt cagcgcgtcg
    16501 gggatcctcg tcgccccgtc gccccgggcg gcgttcagct gcgcctgggt gaggaacagg
    16561 gcgcccgtca ggtccgcgcc cgacagatcg gcgtcgcgca ggtcggcgcc gatgaagtcc
    16621 gcccggcgca ggtcggcgcc cgtgaggtcg gcggcgatca ggtaggcgcc gcgcaggctc
    16681 gcaccgcgca accgggcgcc ccgcaagcgg gcgcccatca ggtccgcgcc ccggtggtcc
    16741 ctgcgccgcc ccggcacctc cgcgcgggcg agctcgccgg cacgcagcag cagcacgttg
    16801 acctcggcgc gcagcgcccc cacgtcgagg gccgacagct cgtcggcgcc gccgcggctc
    16861 agcgcgtcga tccggtcgtg cagccggctc agctccgggt ggacgggccg ggcggccggc
    16921 aggtccagcg cctccgccgc gtaccgcagc agctcgtgca gctgccgcac caccgggaac
    16981 accgcgaaca tcgtgcgggc cgtgtccggt tcggcccgcc agtcgcggcc gccgaacgtc
    17041 acctgcgaca ccttctgccc ggcccccagg cagtcgaaga cggtgcagcc ggtgtacccg
    17101 ctctcccgca gccgggtgtg gatgccgcag cggaagtcgt cccggaggtt gccgcagggc
    17161 gtgccggcgg gcttgtcggc ggcgaagtcg gcggagcggg cgaagggcag ggccacgcag
    17221 cagagcccga agcagttcgc gcagtcggcc ttcaggtcgg ggcggtcggt gtgcgggatg
    17281 tgcgacggca cgacggtggt tctccaacgg gtgtgcgggt gtgcgggcgt gcgggtgtgc
    17341 gggtgtgcgg gtgcggggcc gagccgtggc cccgggtgcg ggccgcggtc ggcgcggtgg
    17401 gcggacgtac gtgctcattg tccctcctct gagcaggggc ccgttcggta acgtagagcc
    17461 atgccacggt tacacggggg tgagtgacgt gggcgtgatc gccggcgagg agcgccaccc
    17521 cgggacactg cccgtccagc acatgggagc cggggaccac gcgttcctct gctacgaccg
    17581 ggagaccccc ggctgggacg tcctcacggc cttcgtgtgg gcgggactgg cgcgggggga
    17641 gaaggtcatc gtgttcggac ccccgcacct gagcgagacg cagctgcgga cgcggctgcg
    17701 cgacgcgccc ggcccgctcg tcgccaccgg cttcgagagc gcgcagctgg agatgagcag
    17761 catgcgcgaa ctgatcctgc ccgcaccgag gttcaccgcc gatcgccagt ggcagcggat
    17821 caccgaggag gtcggcgccg cccgcgccga ggggtaccgc ggactgcgca cgtacatcga
    17881 catgggctgg gtcgcggacc tcggggcgga cctcgacctg atggtggacc gcgagcgccg
    17941 ggccggccac ctcttcgccg acgggttcta cagcgaggtc tgcgcctacg aacgcgaccg
    18001 cttccccgcg ccggtcctgg aggcgatgtg ccgggcccac ccccgcaacc tcctcccggc
    18061 gctgggccgg ttgcgctgcc cgtacggcga gggcgtcctg cgcgtcatcg gcgacgcgga
    18121 cagcgccacg tacgactgct tccggcgggc cgtggacggc gccctgcggg gcctcccgcg
    18181 gggccggccc gccacggtcg acctgcggcg caccggctac ctcggccccg agtgcgcggc
    18241 cgagctcgtc cgcgccctca ccggcccgcc ggcgctccgg tccgtccggg tccgctgctc
    18301 gccggggcac gccctgctgc tgcggcgtct gggcgcggac ccggcagtcc tggacacgac
    18361 gggataggca gatggcgctg gaaacggccg ggacggtgcc cggcaacgga gagggagcgg
    18421 acatcctgct gcggtgtccg ttcggcggct cggacatccc ccggctgcgg gtgctcgtgg
    18481 agagccacgc ggcgcaggcg ggcctgccgg agccgcggcg tggcgacttc gtggtggcgg
    18541 tggacgccgt cgtggtcaac gccgtgcggc acgcgggcgg ttccggggtc ctggtgctcg
    18601 cgcggaccgc gcgggagctg gaatgccggg tctcggaccg ggggccgggg ttcaccgagg
    18661 acgtcatccc cgagctcgct ccggggatcg gcggcgcctg cccgggccgc gggctgtggc
    18721 tgacccggct gatcaccgac cggctgaccg tcacccccgg cccggccggc ggcagcaccg
    18781 tcaccttcgc gatgcgcctg ggggacggcc gctgacggcc tcccggccgg gggccgggag
    18841 gccgggaggc cgggggccgg cccccggccg gggccagggg ctgggccccc gggagacgga
    18901 ggatcagggg agcgggggag cggacggtca ggagggcgcg gcggaccggg cccggtcgat
    18961 caccgtgtcg aggagggaca gcagcgtcgc gcgcacctcg tcccggacgc gcgcgtccag
    19021 cagcaggacg ggcgtctcgg ggtcgcgcag gcgcagcgcc gccctgatct ccccggcggt
    19081 gtacggctgc cggccgtgga agcagttcgc gccgacgacg aacggcagac cgcggctctc
    19141 gaagaagtcg accgcgggga agccccggtc gagccgccgg gtgtccacga ggacgatcgc
    19201 gccgagcgcc ccgtgcagca ggtcgtccca caggaaccag aagcgctcct ggcccggcgt
    19261 gccgaacagg tacaggacga cgcccgcgtc gtcgagcgtg atgcggccga agtccatcgc
    19321 cacggtcgtc gcggacttgg cctcgatgcc gtcgaggtcg tcgacgccca cgccggcggc
    19381 ggtgaggcgc tcctccgtgc gcagcggctc gatctcggag accgcctcga ccagggtggt
    19441 cttgccgacc ccgaagccgc cggcgacgag gatcttgacg ggggccggct cctggccgcc
    19501 gggggcggtg tcacatccgg gcaaggttgt ccctgattct catgagcagg tggacgtcgg
    19561 tggtcgcggc cgcctccagg ggcggccggt ggtggacgag cccgcggtcc gcgagctcgc
    19621 cgaggagcag cgtcatcggc gtcagccgca tccccatccg ggcggcgatc tcggcgaccg
    19681 cccgcccggt cggtgccggg cacagggcga ggacgtgccg ccactccgtg ggcagcccgt
    19741 cgggggcgtc gccgccgacc gccgccgtga tggtggtgtc catcgtcagg gcggtccgcg
    19801 gcgcggccgt acggccgtcg gtgacggcgt acagccgcgg ccggcggccg ccccggcggt
    19861 gcggctcgtc gggcattacg gggcgggcgg cgacgacggc ggctgcgcgc ggtcaggcgt
    19921 gcccagccac tcgccgagcg cctgcgcggt ccgcaccgcc tcaccgccga gctcgccgag
    19981 gcgtgccttg cggttggtga cgacgacgag cgtgctgccc tcgccgcacc cgacgaggca
    20041 caggtaccgc tcgtccatct cgaccagctg ccggatcacc cgtccgccgt cgacgtcgcg
    20101 ggatatcgcc cgcatcgtcg cggcgacacc ggaggacgcc gccgcgatgc gttcggcctg
    20161 cgcgcggtcc agcaggtagg cgctgagcat gatcccgtcg ttggacagga gcaccgcccc
    20221 ctcgatgccg gcgatcctgc tcaggttgtt gtccaggacg ctgtagatca tgtcgttcgt
    20281 cgttgtcatg gctgatcctg tcggagctct tcttccactt tccgggtccc gtcctcgtac
    20341 tccgcccagg cgtcggccac ttcctcgggg ctcgccccgt cgtggccggt gcccgggccc
    20401 gtcccggtct cctgggcggc cgcgccgccg tccccggggg gcggcgtgcg caactgctcg
    20461 accaggtgcg tctgcggtac gcgctccggc aggggcgggc gggcggcgcc gtccccgtcc
    20521 ccgccgggag gcggtgcgtc cttgcgccgc cgcacgggca gcgccgcgcc ctgccgcgac
    20581 gccggccgcg acgtctcgcc gcggtcgtcc ggccgccgct cggtcgtagc cggcgccggg
    20641 gccggtccgc gcgccggggg acgggcctgg gccggcagtc gggcgggggc cgcggtcgga
    20701 tccgccgtcc cgtccaccgt cccgtccacc gccccgtccg ccgtctcggg gccggtcggg
    20761 acgagcagct ctcgcgggac gagcaccacg gccgccgtgc cgccgtacac cgagcgacgc
    20821 agcgtcaccg tcgcgcccag ctggtgggcg aggtggccca ccacgaacag gcccagccgg
    20881 tgcgcgtttc gcgcgagcac ggcgtacggc ggggccgagt ggaggcgggc gttcat
//
