LOCUS       NZ_CP102332            31707 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Streptomyces changanensis strain HL-66 chromosome, complete genome.
ACCESSION   NZ_CP102332
VERSION     NZ_CP102332.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces changanensis
  ORGANISM  Streptomyces changanensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6817869)
  AUTHORS   Wu,H. and Han,L.
  TITLE     Streptomyces changanensis sp. nov., an actinomycete isolated from
            soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6817869)
  AUTHORS   Wu,H. and Han,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2022) College of Forestry (Academy of Forestry),
            Northwest A&F University, Northwest A&F University, Yangling,
            Shaanxi 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.9; Pilon v. 1.24
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 187.45x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024600715.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 19:18:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,071
            CDSs (total)                      :: 5,982
            Genes (coding)                    :: 5,812
            CDSs (with protein)               :: 5,812
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 170
            CDSs (without protein)            :: 170
            Pseudo Genes (ambiguous residues) :: 0 of 170
            Pseudo Genes (frameshifted)       :: 70 of 170
            Pseudo Genes (incomplete)         :: 131 of 170
            Pseudo Genes (internal stop)      :: 9 of 170
            Pseudo Genes (multiple problems)  :: 37 of 170
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:13:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5406547
            Orig. end                         :: 5438254
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102332.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..31707
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="17"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     cand_cluster    1..31707
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31707
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:26707](+)"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..26707
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     misc_feature    327..345
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.32"
                     /tool="antismash"
     gene            580..987
                     /gene="msrB"
                     /locus_tag="NRO40_RS23630"
                     /old_locus_tag="NRO40_23630"
     CDS             580..987
                     /EC_number="1.8.4.12"
                     /GO_function="GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /gene="msrB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007501099.1"
                     /locus_tag="NRO40_RS23630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23630"
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="WP_058942553.1"
                     /transl_table=11
                     /translation="MAYEVDKPDEQWRTELSPQEYHVLREAGTEPAFTGEYTDTKTKGV
                     YSCRACGAELFTSETKFASHCGWPSFYDPKDGAAVELVEDRSYGMARTEVRCARCGSHL
                     GHVFEGEGYPTPTDQRYCINSVSLRLAPDEG"
     gene            complement(1109..2101)
                     /locus_tag="NRO40_RS23635"
                     /old_locus_tag="NRO40_23635"
     CDS             complement(1109..2101)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012514.5"
                     /locus_tag="NRO40_RS23635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23635"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_058942552.1"
                     /transl_table=11
                     /translation="MLETPHPPSVLRSTVGVLVTDERARPLLVRPAGGGGPWALPSCGC
                     ALSLPCGTVPARPVLVFDRVAAGCEGRLVVDGGRLDAAGLGGVEGPVTCVEPAVAAGLL
                     PAAEGRRMLAALRARVAGAGPVVLEEGRPAGPAPVLDRLGLFGRPRTAQELPWYEGTPV
                     PTQLTPRQAWGWLFAPDGRVLVLVDPRDGHAELPGGTIEPQDPSPAAALVREAGEEASV
                     TTGEPVYLGHLPDVHDGRPVARTRFAAPLTGMGPSAVDPALNIRYARLLVTPQQAVDLL
                     GWGAMGRAQAAAAVRAAEAWGAPRAEARPVEEVHAAGGLPARPGAAAHD"
     gene            2495..2647
                     /locus_tag="NRO40_RS23640"
                     /old_locus_tag="NRO40_23640"
     CDS             2495..2647
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS23640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NRO40_23640"
                     /product="hypothetical protein"
                     /protein_id="WP_157901875.1"
                     /transl_table=11
                     /translation="MPTRFIAALACSTAACVAVLIVDPAKRTDELQSSSVSNVVENSED
                     SWGWD"
     gene            2671..3381
                     /locus_tag="NRO40_RS23645"
                     /old_locus_tag="NRO40_23645"
     CDS             2671..3381
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS23645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NRO40_23645"
                     /product="hypothetical protein"
                     /protein_id="WP_232791095.1"
                     /transl_table=11
                     /translation="MEDRERLAADLAELPRLYAEMEYLMGPVATGPLQRVSGTRSTDRV
                     FDEAAAAARSAIVGVLASWAGVAVETYGPPVPERRVPELAAFLARHLDLLANHPAVADM
                     AGEIAQVTDGARRIARPDGVRRIRVGACVRDGCGGEVVVTMGGGADGWARDVRCGAGHV
                     WQPHEWLDLRGRMAAAEPARAARRTLPTRLAAVAVGVSEATVRKWASRGKLTRHGTATR
                     AEYDLEELTLLAAG"
     misc_feature    complement(3450..3467)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 18.77"
                     /tool="antismash"
     misc_feature    complement(3529..3543)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.74"
                     /tool="antismash"
     gene            3647..4885
                     /locus_tag="NRO40_RS23650"
                     /old_locus_tag="NRO40_23650"
     CDS             3647..4885
                     /NRPS_PKS="Domain: AMP-binding (80-307). E-value: 3.7e-12.
                     Score: 37.4. Matches aSDomain:
                     nrpspksdomains_NRO40_RS23650_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.5"
                     /locus_tag="NRO40_RS23650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23650"
                     /product="AMP-binding protein"
                     /protein_id="WP_058942551.1"
                     /sec_met_domain="AMP-binding (E-value: 8.4e-06, bitscore:
                     23.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLDSDDATLKSLEEIERARAAWEDRPRHSSPDAAYRAFVDELRR
                     DVPFYRDAGVELPLTDRAVHQENGELFRSPRVAATYRLSSSGTTGKPLEVRLDDAAWYA
                     VNYRFFAQIRDVAGLPADLFRRGEPAVVFISNKPGRASFVRPLPPLGNGLYVRLQLGGA
                     DALRLFSRLRAPVLYGKPTYLLDLRAALLRQGAAEPPWTPRLLLVSGEPLHDDDRRRLT
                     DYFRAPVVDALASTEGGLVAATTPDARTYRVFGENVRLEVLDEHGAPRPAGAGELVLTN
                     LVNRGTFVARYRTGDHAELDTAPDGTQRLLRLRGREPGTLRFRTAELPAETVTGAVGHL
                     PGLGDFQVDLRDPDRTVLRWAPEPGRPDEEGLRRELRAALDRLLPGEEPLLERHERITP
                     PGGKKRRYLTAPA"
     aSDomain        3887..4567
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NRO40_RS23650_AMP-binding.1"
                     /evalue="3.70E-12"
                     /label="NRO40_RS23650_AMP-binding.1"
                     /locus_tag="NRO40_RS23650"
                     /protein_end="307"
                     /protein_start="80"
                     /score="37.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="YRLSSSGTTGKPLEVRLDDAAWYAVNYRFFAQIRDVAGLPADLFR
                     RGEPAVVFISNKPGRASFVRPLPPLGNGLYVRLQLGGADALRLFSRLRAPVLYGKPTYL
                     LDLRAALLRQGAAEPPWTPRLLLVSGEPLHDDDRRRLTDYFRAPVVDALASTEGGLVAA
                     TTPDARTYRVFGENVRLEVLDEHGAPRPAGAGELVLTNLVNRGTFVARYRTGDHAELDT
                     APDGT"
     gene            5001..6026
                     /locus_tag="NRO40_RS23655"
                     /old_locus_tag="NRO40_23655"
     CDS             5001..6026
                     /EC_number="2.6.1.9"
                     /GO_function="GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (43-278). E-value:
                     1.8e-28. Score: 91.6. Matches aSDomain:
                     nrpspksdomains_NRO40_RS23655_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012382.5"
                     /locus_tag="NRO40_RS23655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23655"
                     /product="histidinol-phosphate transaminase"
                     /protein_id="WP_058942550.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.8e-26, bitscore:
                     91.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRDLTWTGNHFLDPAAHTARLLRAAEDIDITNKDEVWSRQVATA
                     AAAHFGVPADFVRVGAGATQLIDTLLRSAYRGLVVDVTPNFHLTATVARQQGWEYLAVP
                     VREPGELLPALEPHLGRDDAITVLCSPRNPLGYQFPVEDVAALLERARGLVVLDEVYAD
                     FAPATALPLVERFPNLVVMRTFSKAWGLANLRIGFAVSASFAREDFPFWLMPNSVSGVA
                     QRTALGLLADPAPVRDSVRRVHACRERLVAGLSGVEGLRLWPSDANYVCLETPRAAEVV
                     EELGHAGYRTRLVHDLRGYPADWPAGVRIVVPPEPDVDRVVKGVLHAHQGPGAAPAPAD
                     R"
     aSDomain        5130..5834
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NRO40_RS23655_Aminotran_1_2.1"
                     /evalue="1.80E-28"
                     /label="NRO40_RS23655_Aminotran_1_2.1"
                     /locus_tag="NRO40_RS23655"
                     /protein_end="278"
                     /protein_start="43"
                     /score="91.6"
                     /tool="antismash"
                     /translation="TAAAAHFGVPADFVRVGAGATQLIDTLLRSAYRGLVVDVTPNFHL
                     TATVARQQGWEYLAVPVREPGELLPALEPHLGRDDAITVLCSPRNPLGYQFPVEDVAAL
                     LERARGLVVLDEVYADFAPATALPLVERFPNLVVMRTFSKAWGLANLRIGFAVSASFAR
                     EDFPFWLMPNSVSGVAQRTALGLLADPAPVRDSVRRVHACRERLVAGLSGVEGLRLWPS
                     DANYVCLETPRAA"
     gene            6023..7999
                     /locus_tag="NRO40_RS23660"
                     /old_locus_tag="NRO40_23660"
     CDS             6023..7999
                     /NRPS_PKS="Domain: Abhydrolase_1 (382-511). E-value: 5e-09.
                     Score: 28.1. Matches aSDomain:
                     nrpspksdomains_NRO40_RS23660_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012546.5"
                     /locus_tag="NRO40_RS23660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23660"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_058942549.1"
                     /sec_met_domain="PF00561 (E-value: 4.8e-07, bitscore: 28.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 6.7e-43, bitscore:
                     145.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGGPARATGGAATGGGAGRTDGPPSLSADGRYAAWLSAGDGATR
                     LVVHDLAARREHGRSDVGAARCRAFTWSHLPGVGLALSDPDGSESWTLFRVDVADGTWT
                     PLGAPGRRTRLAGLSPQRPEEVLLAAEGGEPGRLDHHLVSLRTGARTEVLRDRGYAAVY
                     ADTSLRPRLTETVGDDGSRDLWHGEPTAGRPFLHVPHEDALTVRFLAFAPDGDTAYFVL
                     PDGPDGVRLTALACRDGAPARELRTEHRVRGGDIPDVLFEPGTGRPGIVQTERERRACV
                     ALDPRWAPVLEHLRTRLGTEPVVTERRGGRWLVAAHRPEHDTHWYVHEPAGGDTWRLGA
                     ARPGTPPSSVTCRAVGVPLRGGGEAVTYVTRGTARGDGDGPGPAVLLVHGGPWRRSRWE
                     YAERRTWLAERGCTVIEPNFRGSTGFGPAWTNAADRQWGLAMQDDLEDALDWAVAEGVA
                     DPDRLALVGGSYGGYAVLQMAATTRRDLRCVVATSPLTDLVRFLEEPPAFWRTAAPMLH
                     RRVGDPADPDQRAALRAVSPVDNAAGVRCPVLLVHGANDSRVPAEMATRMFMALARAGK
                     DATLALFPDEGHEVVTTGNRAALHAVTAAHLDTHLFDRPPAADAGPPGDTTLKLFDTPH
                     AARRKAASAPDPGDVHGTALHAQ"
     aSDomain        7169..7555
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NRO40_RS23660_Abhydrolase_1.1"
                     /evalue="5.00E-09"
                     /label="NRO40_RS23660_Abhydrolase_1.1"
                     /locus_tag="NRO40_RS23660"
                     /protein_end="511"
                     /protein_start="382"
                     /score="28.1"
                     /tool="antismash"
                     /translation="PAVLLVHGGPWRRSRWEYAERRTWLAERGCTVIEPNFRGSTGFGP
                     AWTNAADRQWGLAMQDDLEDALDWAVAEGVADPDRLALVGGSYGGYAVLQMAATTRRDL
                     RCVVATSPLTDLVRFLEEPPAFWRT"
     gene            7974..9227
                     /locus_tag="NRO40_RS23665"
                     /old_locus_tag="NRO40_23665"
     CDS             7974..9227
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS23665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NRO40_23665"
                     /product="hypothetical protein"
                     /protein_id="WP_058942548.1"
                     /transl_table=11
                     /translation="MALHFTRSNALLLLTPKTGSTWIRRKVRELGLEVAEVGDPAMREH
                     DLLADFDRSRYGFVGAFVRDPLEWYRSYWSYRMEKGWRPQYPLDEHCESDDFQTFVRRA
                     VTVLPGALGNIYTSYVGTPDDEVDFVGRQEDLAADFARFLKLAGEEFDASVLAEGDRIN
                     ATSIRPDYPEELKELITLSEWETMARFGYLDARPDPIGLAEMRARYPEDAGDLRLLSLW
                     TEKIHWAPDDVKRASGRPVRPETRYARVHSNFALFAQHKKQDPEYAGTRYREALRLDPA
                     HPRTLCNYALYVAEHEDDTAGARALMLRALSGRPNHPYTLGKLAKLTAERLDDPDLAEV
                     LYRQSLAANSDQRELRAEFARFLAGRGKTDEAVALLAEEAESPRADRLTLLTHASVLAR
                     AGRITEARRFQQLAATAA"
     gene            9248..10123
                     /locus_tag="NRO40_RS23670"
                     /old_locus_tag="NRO40_23670"
     CDS             9248..10123
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (25-268). E-value: 2.4e-14. Score:
                     45.7. Matches aSDomain:
                     nrpspksdomains_NRO40_RS23670_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.5"
                     /locus_tag="NRO40_RS23670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23670"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_058942547.1"
                     /sec_met_domain="TauD (E-value: 2.4e-12, bitscore: 45.7,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITEDRLARTIQDESVSAAGRTVAQTVAAAREVVGRNRICLVRD
                     FPLDPDRYLEFLGAFGEPLRNYSSLSELAKTDPHPQINRVKYKKKTEGAQSVHYVAGGL
                     RPHSARSWCTPRPAFFAMLMVEPGWREVPAGQRGESVVVSWYDLFTRLAERDGAVFEEH
                     FARLSGTPITFRANNVREELSDLPLLYPLDDSRGRYDVGVRLKQDLRDKIAGIEDQLPD
                     ADAYRKSLDYLLDASVEDGLFSCFPMERGDLLLLDNHRFAHGRQKIVGEYAVDGEARTN
                     DRELWSVTVR"
     aSDomain        9323..10051
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NRO40_RS23670_TauD.1"
                     /evalue="2.40E-14"
                     /label="NRO40_RS23670_TauD.1"
                     /locus_tag="NRO40_RS23670"
                     /protein_end="268"
                     /protein_start="25"
                     /score="45.7"
                     /tool="antismash"
                     /translation="QTVAAAREVVGRNRICLVRDFPLDPDRYLEFLGAFGEPLRNYSSL
                     SELAKTDPHPQINRVKYKKKTEGAQSVHYVAGGLRPHSARSWCTPRPAFFAMLMVEPGW
                     REVPAGQRGESVVVSWYDLFTRLAERDGAVFEEHFARLSGTPITFRANNVREELSDLPL
                     LYPLDDSRGRYDVGVRLKQDLRDKIAGIEDQLPDADAYRKSLDYLLDASVEDGLFSCFP
                     MERGDLLLLDNHRFAHGRQKI"
     gene            10161..10400
                     /locus_tag="NRO40_RS23675"
                     /old_locus_tag="NRO40_23675"
     CDS             10161..10400
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS23675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NRO40_23675"
                     /product="hypothetical protein"
                     /protein_id="WP_058942546.1"
                     /transl_table=11
                     /translation="MDNPVPTTPGEDAAEPTGQAAEQADLAAVCAELQGELDALMAGPG
                     TNAAAQSLDTAVSSLKEVEQRNVSSVQLVALADR"
     gene            10580..11638
                     /gene="pyrB"
                     /locus_tag="NRO40_RS23680"
                     /old_locus_tag="NRO40_23680"
     CDS             10580..11638
                     /EC_number="2.1.3.2"
                     /GO_function="GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137157.1"
                     /locus_tag="NRO40_RS23680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23680"
                     /product="aspartate carbamoyltransferase"
                     /protein_id="WP_058942545.1"
                     /transl_table=11
                     /translation="MSLTGKHILSSDLFTRDDLERLFELADVLTPVARGRKVTRVLEGA
                     VMASLFFEASTRTRLSCESAFLRLGGGVTTTTGVELLSIAKGESLADTSRVVSGYCDLV
                     VMRHPDEAAVHEFADATHVPVVNGGNGAGEHPTQALLDMFTMHREFHRLGRDIDGARIA
                     MVGDLRHGRTVHSLIKLLSRYDKLTLVCVSPDSLGMPAPLLELAASRGHHVEVSDRPEA
                     GLRDADLVYATRLQTERFADLPVPYSDEFRIDRALVDRVCRPDTVIMHPLPRDSRPAAN
                     DLGTDLNTDPRLAIFRQTDAGIPIRMALFASVLGVADAIRPSLRPATWYRPDFTGPDDA
                     PFYRNTAVEGIA"
     gene            11732..13039
                     /locus_tag="NRO40_RS23685"
                     /old_locus_tag="NRO40_23685"
     CDS             11732..13039
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.5"
                     /locus_tag="NRO40_RS23685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23685"
                     /product="MFS transporter"
                     /protein_id="WP_058942544.1"
                     /transl_table=11
                     /translation="MSGETRREKRRRDFAAYRHPIVAVTMASTFFLKLVSYLCIPFMTI
                     FLSRNADLPAHVIGLLVGLNQIGSLTAGFFSGVLADRIGRRRILLVGLFGTALVFGLLF
                     AVATYLRQSLAFPVLFGVLNVSYGVMSAFFWPVTQVVMADSLPKEQRPVLFRHRYVLTN
                     TAVAVGPPTGAFLGLASDRLAFVIAGGCYLLFALAYAWLGRGTEYGAPVPTPAASAPAA
                     GAKAAGDRRSFTGALRVLAADRAFRSLTVSMILFTLAYCQIESNLSRIVSTGFPDGIRF
                     FAVLLTVNAVAVIALQPLASRAAERLGPRRTLLTGNALFAVVCLLFPLTGSGRAALVAL
                     VVLISLAEVLVVPTVSVVVDELAPPDLRGTYFGAATLRNLGLGLGPAAGGLVLTLFPRE
                     LLFVFMGLCAAAAWAVIHFTLRENAGAHPGPASEPV"
     gene            13005..15017
                     /locus_tag="NRO40_RS23690"
                     /old_locus_tag="NRO40_23690"
     CDS             13005..15017
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207: inositol monophosphatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012673.5"
                     /locus_tag="NRO40_RS23690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23690"
                     /product="inositol monophosphatase family protein"
                     /protein_id="WP_232791094.1"
                     /transl_table=11
                     /translation="MRILVLHQNLFERLAYERAIDHSVHDVVYAGTPQYLANIPAHVRC
                     GTFPLDPARPVADQLRPWMAGQPPFQRIIARHEKLITPAAELRDAFGIPGMGAAAARNF
                     RDKVTMKRTLARAGFRVPRFVPADRPAAPDGPAAPDRPGAGPGWRGRTIVKPRDEGGSQ
                     GVRLFETLDEALEFVRAAAAQSPADPAAQTGTEQGTGGGFAARYELEEYVEGPIWHVDG
                     FLFKGEAVVAQPSRYVGTPLGFENGAPIGSVQFDHPELTEWAVRCVRALGGETLTFHLE
                     AIMTPSGPVFMEVAARCGGGYIVDVTERRTGAHLHTLDMASDVDDALAERFLGPPAPGL
                     AHGFFLFPGHVHGGAAVSVRGARALLDDPVVVRHRITAPGTTTPTSHSYRPEHLPLSGV
                     VRGPDPEALVRYVERVLEQVTVEDDHRLAHRLAEEAGELLLKLRAESGFADPAALKAAG
                     DRLSHEFLAAALAAERPGDAVLSEEGKADAARLTAERVWIVDPLDGTREFSEPGREDWA
                     VHVALWTGGRLAAGAVALPAQGVTLSTGTPPPTPDSPADRLPVLGSRSRSPAFLTQVAG
                     RIGAELAGMGSAGAKTAAVIRGDARAYLHAGGQYEWDSAAPAAVALAAGLHVSRLDGTP
                     PVYNRADPYLPDLLVCRPQDAAALLAAVAEATTGS"
     gene            15064..15657
                     /gene="cysC"
                     /locus_tag="NRO40_RS23695"
                     /old_locus_tag="NRO40_23695"
     CDS             15064..15657
                     /EC_number="2.7.1.25"
                     /GO_function="GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037097.1"
                     /locus_tag="NRO40_RS23695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23695"
                     /product="adenylyl-sulfate kinase"
                     /protein_id="WP_079047103.1"
                     /transl_table=11
                     /translation="MTDTDNSTFEAVPAHPAGPAGRGATVWLTGLPSAGKTTLARALAE
                     RLRAAGHRTEVLDGDEVREFLSAGLGFGRADRDTNVRRIGFVAELLASNGVKVLVPVIA
                     PYADSRAEVRAHHRREGTPYVEVHVATPVEVCSERDVKGLYARQAAGEISGLTGVDDPY
                     EEPDAPDLRLDTAGRPVAGSAADIHALLVGRGLA"
     gene            15654..16577
                     /gene="cysD"
                     /locus_tag="NRO40_RS23700"
                     /old_locus_tag="NRO40_23700"
     CDS             15654..16577
                     /EC_number="2.7.7.4"
                     /GO_function="GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514607.1"
                     /locus_tag="NRO40_RS23700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23700"
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="WP_058942543.1"
                     /transl_table=11
                     /translation="MSAVTGATGVYRPTHLDVLESEAVHIFREVAGEFERPVVLFSGGK
                     DSIVMLHLALKAFWPAPVPFSLLHVDTGHNFPEVIEYRDRTVAKHGLTLHVARVQEYVD
                     DGRLTERPDGTRNPLQTVPLLDAIERHRFDAVFGGGRRDEEKARAKERVFSLRDEFGAW
                     DPRRQRPELWDLYNGRHMVGEHVRVFPLSNWTELDVWQYIEREGIELPEIYFAHEREVF
                     SRSGMWLTAGEWGGPKESEPVEKRMIRYRTVGDMSCTGAVDSDATTVADVIAEIAASRL
                     TERGATRADDKLSEAAMEDRKREGYF"
     gene            16579..17880
                     /locus_tag="NRO40_RS23705"
                     /old_locus_tag="NRO40_23705"
     CDS             16579..17880
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018383177.1"
                     /locus_tag="NRO40_RS23705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23705"
                     /product="sulfate adenylyltransferase subunit 1"
                     /protein_id="WP_058942542.1"
                     /transl_table=11
                     /translation="MTATTHTRHDPAAATLLRFATAGSVDDGKSTLVGRLLHDSKSVLV
                     DQLEAVEAASRRRGQDVPDLALLTDGLRAEREQGITIDVAYRYFATPRRRFILADTPGH
                     VQYTRNMVTGASTADLTVVLVDARNGVVEQTRRHAAVSALLRVPRLVLAVNKMDLVGYD
                     EAVFAAVADEFTGYARRLGTADVVAIPLSALEGDNVVAPSAHTDWYSGPTLMEHLEGVE
                     VAAGSPDAPARFPVQYVIRPQSGAHRDYRGYAGRLASGVLRPGDTVTVLPSGQRATVAG
                     IDVLGTPASAARATQSVTVRLAEDVDVSRGDLIAAGAAPRLTRDVTATVCHLHERPLRT
                     GDKVLLKHTTRTVRAVVREITYRTDVDTLERRDAAGALDVNDLGRVVLRTAEPLALDDY
                     ADNRRTGAFLLIDPADGTTRSAGLVGETSAWGAP"
     gene            17877..19268
                     /locus_tag="NRO40_RS23710"
                     /old_locus_tag="NRO40_23710"
     CDS             17877..19268
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046079.1"
                     /locus_tag="NRO40_RS23710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23710"
                     /product="cation:proton antiporter"
                     /protein_id="WP_058942541.1"
                     /transl_table=11
                     /translation="MTDVDLFRLFASLMLLLLAAHLMGRLFARLRQPPVIGEITGGLLL
                     GPSLFGLLAPGAQGWLFPPTGPAATGLALVYQLGVLLLMFLAGLQMRAVFSRHDGRAVV
                     LIAVVGMVIPFGCGLLLVRVVDLSSVVGEAGDHTALTLVIACAVAITSIPVISRIMMDL
                     GIAGTSFARVVLSVAVLEDIVLNVVIAVALGMVGGGPHDAFGAPALLGVGTGDGAIAYH
                     ALVSVVFFGLTAGVGTLLRRRTAARPDVPAAGPGPTAGRPEAGERPGAGVQVAVQVAVV
                     LGAGGTCVFLGITPMYGAFLVGLMTSWSRGAGEPDPMAAVRGFATGFFIPVYFAIVGLK
                     LDLVHAFDPLLTVAFTAFACVVKAASVYLGARWAGRPRAGALNLAVAMNARGGPGIVLA
                     TLAYDARIINATLFTTLVLTAVITSLMAGGWLESAIRRGLLPRDGDEERPPVADRTDKI
                     PAGAR"
     gene            19265..19738
                     /locus_tag="NRO40_RS23715"
                     /old_locus_tag="NRO40_23715"
     CDS             19265..19738
                     /EC_number="2.7.1.25"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS23715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NRO40_23715"
                     /product="adenylyl-sulfate kinase"
                     /protein_id="WP_058942540.1"
                     /transl_table=11
                     /translation="MNQHATVCTCLPGATLWLAPPTAGTAPADAATGTAPAAGPVAPDA
                     AGAGHAAGAAALAERLRGEHRRVEVLEGTAGLGSPGDTAAAAVLRTGLVAEILARNGIA
                     VLVTGVAPDECALASVRERHREGGVPFLTLPSGGSTDELYAALVANGLGVQAS"
     misc_feature    complement(19774..19787)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.92"
                     /tool="antismash"
     gene            19782..20639
                     /locus_tag="NRO40_RS23720"
                     /old_locus_tag="NRO40_23720"
     CDS             19782..20639
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (18-261). E-value: 5.1e-12. Score:
                     38.0. Matches aSDomain:
                     nrpspksdomains_NRO40_RS23720_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.5"
                     /locus_tag="NRO40_RS23720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23720"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_157901874.1"
                     /sec_met_domain="TauD (E-value: 5e-10, bitscore: 38.0,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDSIAIDCSGMSPADIRAATVASVAEHRLAYLRGFPLDVARYTD
                     LLEHLGELCPNYAAGSASDAYALHPAVNTVRCRAPEPGGEQRVQEKAGSLPLHTGRSFA
                     RRRPLHLAMLMADPGWRDFAPGHNGESLIVRWGDVLRAVRERHPEHWAEDLRLLTANSV
                     SFPASHLDEEPSALPFLYVPGTPRLTPVPDDVAVRLPQDVTRLGRAAERMPDGERWYEA
                     VVRFKATADDPEVHQAYVMEAGDVVVIDNDRYGHGRQEVVATRTAPDGGTAVNPRTIWS
                     VNIQ"
     aSDomain        19836..20564
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NRO40_RS23720_TauD.1"
                     /evalue="5.10E-12"
                     /label="NRO40_RS23720_TauD.1"
                     /locus_tag="NRO40_RS23720"
                     /protein_end="261"
                     /protein_start="18"
                     /score="38.0"
                     /tool="antismash"
                     /translation="AATVASVAEHRLAYLRGFPLDVARYTDLLEHLGELCPNYAAGSAS
                     DAYALHPAVNTVRCRAPEPGGEQRVQEKAGSLPLHTGRSFARRRPLHLAMLMADPGWRD
                     FAPGHNGESLIVRWGDVLRAVRERHPEHWAEDLRLLTANSVSFPASHLDEEPSALPFLY
                     VPGTPRLTPVPDDVAVRLPQDVTRLGRAAERMPDGERWYEAVVRFKATADDPEVHQAYV
                     MEAGDVVVIDNDRYGHGRQEV"
     misc_feature    20676..20691
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.12"
                     /tool="antismash"
     gene            20683..21723
                     /locus_tag="NRO40_RS23725"
                     /old_locus_tag="NRO40_23725"
     CDS             20683..21723
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS23725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NRO40_23725"
                     /product="hypothetical protein"
                     /protein_id="WP_058942538.1"
                     /transl_table=11
                     /translation="MTRIIASCTRGTHGLPDELTAVEGVGQAGDVVVARVVSVGAYKAV
                     ENTSGRDVRVRVGDEVVGVLGERHSTTSIYGGLPEGGLPVKAGDPADLMAVGGIIGIAA
                     SSPSSLGTATALELVGLAADRDGRVLRLRRKAADTVPATPVVFVGGTAAEVGKTTFASA
                     LVHHLTARHGLRVGVTKLAGTGRLRDLLTLADAGAHCAADFVDAGLGTTYGHGADAVVG
                     AARHLVGRLADEGAEIVVAELGGDLWGAGIPDILRDPGLVATARALVLVPSDTMASLGV
                     ETWLGRNDITIPAVHGVPHRNVMAARERADRGMGVQLVDPHDPDDLERMVREVLFAGRE
                     PGEGTR"
     gene            21720..23042
                     /locus_tag="NRO40_RS23730"
                     /old_locus_tag="NRO40_23730"
     CDS             21720..23042
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024925.5"
                     /locus_tag="NRO40_RS23730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23730"
                     /product="acetyl-CoA carboxylase biotin carboxylase subunit
                     family protein"
                     /protein_id="WP_058942537.1"
                     /transl_table=11
                     /translation="MSPAAPHVALLLGAGGISPDAALEAAITVTRQVTVVWYEGGPTAA
                     AATALKERWSRECTGEWLATGDHREIPGMLAELHRRRPLHGVATFGEPLIVAQAEAQEL
                     LGLPGNPPGAVRTAQSKLDQRRRLRGAGVETIRFRVVRDQGDVSEAVAEVGFPAILKPV
                     HGAASFLVSKVHDEAELRARLAEALTAYRQSPLLDPEPLFVLEQLLVGDEWYEEPGFAD
                     YVSVESLVADGRVTHVGITDKLPQHGFVETGHAAPTSLPAHRQRQVLDHTGRIIGALGI
                     RWGATHVELKLTPDGPACIELNARLGGPMGHLLRAATGADIAADVVRLALGRPPEGDYG
                     RVRHALYRCVPPPAEPVRMTAQTPREELLAAFPELVFCKTRFAPGAELHPDRPYNVLTF
                     LVTGDDMRSCLATARRVEDAYRAEFVPLAGGPPAARAAATP"
     gene            23072..23593
                     /locus_tag="NRO40_RS23735"
                     /old_locus_tag="NRO40_23735"
     CDS             23072..23593
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135412.1"
                     /locus_tag="NRO40_RS23735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23735"
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="WP_058942536.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.8e-10, bitscore:
                     38.0, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSTATGATARALLDSLVDHGFTLATGVPCSLLTGAFRLLEDPGD
                     DARLARLRYVPAPREDSAIGIASGAVVAGERAVVLMQNSGLGYSLNVITSFNLIYDVPV
                     LLIVSWRGHDGNDAVEHDVIGAELLRLLELFRLPYTVLDHADPAASVATVIDLMDKEQR
                     CGVLVVREGI"
     gene            23593..24177
                     /locus_tag="NRO40_RS23740"
                     /old_locus_tag="NRO40_23740"
     CDS             23593..24177
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014794.5"
                     /locus_tag="NRO40_RS23740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23740"
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="WP_058942535.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.6e-18, bitscore:
                     63.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPAPTPSAALTLSDVAAELLDRHPDAVIVSTCGFTTRELFNAA
                     DRPENFYLVGSMGIAAPVALGIALARPARTVIALDGDGSLLMNLGVLPLVAGAGVPLLH
                     VVVDNGMHESTGGQATVGRADFTALALAAGYAHAVRVEDAAGLRAADLTPRPALLHALT
                     GPRTGGPGRRVTHTPQQIVERLSAALDPVAA"
     gene            24216..25112
                     /locus_tag="NRO40_RS23745"
                     /old_locus_tag="NRO40_23745"
     CDS             24216..25112
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonates-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018566041.1"
                     /locus_tag="NRO40_RS23745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23745"
                     /product="isocitrate lyase/phosphoenolpyruvate mutase
                     family protein"
                     /protein_id="WP_058942534.1"
                     /sec_met_domain="phosphonates-like (E-value: 4.2e-123,
                     bitscore: 408.2, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.7e-106, bitscore:
                     353.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.6e-60, bitscore:
                     203.0, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTRALREALNGPAIARIMGAHGALSAKLGEEAGFEAIWASGLE
                     ISAARAIPDANILSMAECLEAAAEIAGAVGIPVLADCDSGFGGVGNVVHMIRSYEARGM
                     AGVCIEDKMFPKMNSFVEGNQDLAPLGDFAAKITAAKEARTDPDFVVVARIEALIAGAG
                     MEEALRRAAVYERAGADALLIHSKQSAPDEVFAFRESYRGALPVIVVPTTYPQVTADEL
                     TTRGFGGVIYANQGLRASISAMRDVLAQIGGAGSTYGVEGSIAALKDVFALQRVDELLA
                     LQQRHDRLTATYAAPLD"
     gene            25232..26707
                     /locus_tag="NRO40_RS23750"
                     /old_locus_tag="NRO40_23750"
     CDS             25232..26707
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012398.5"
                     /locus_tag="NRO40_RS23750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23750"
                     /product="aldehyde dehydrogenase"
                     /protein_id="WP_079047101.1"
                     /sec_met_domain="Aldedh (E-value: 3e-150, bitscore: 499.2,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEPRRTAPAPAVVEVRNLVGDTWRDALSGRRQENRNPARLGEIVS
                     RSADSDAADVRDAVAAAAAALPAWHDLGPVRRGEIVMRAASLVRERREEFAVAITREQG
                     KLLREARGEVDRTVALMEYTAGEGRRLGGATLPADDPRTLALTRRHPIGVVGLVTPWNF
                     PLAIPAWKAAPALVAGCTAVLKPSPLTPYTAALLVECLLAAGATGGVLNLVHGGRAAGE
                     ALVAEPAVSGVSFTGSVEVGRAIHTAGAPRFLRTQLEMGGKNAALVLADADLDLAADAI
                     VAGAFGQAGQRCSATSRVVVDRAVRDGLVARLTARADALTAGDGLDPDAGLGPVVSEER
                     LRACVDGVRRAVADGASVVRGGERLGGALADGCFMAPTVLVDVEADSFVAQEEIFGPVL
                     SVIDCDGFEDGLRVVNSVRYGMAAAVFTGDQSLALRALDRIDAGMLHVNRPGVGAYPHM
                     PHVGAKESQYGPAECSPQVWDFYTEWRTACVSY"
     misc_feature    26854..26869
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     gene            26966..27892
                     /locus_tag="NRO40_RS23755"
                     /old_locus_tag="NRO40_23755"
     CDS             26966..27892
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888899.1"
                     /locus_tag="NRO40_RS23755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23755"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_232791093.1"
                     /transl_table=11
                     /translation="MSQPGWGVAEIAGDLGMTGPEVRACLDELAELSMLYSGGTAAAPV
                     ALPPGIALAALLHRRELEIQAQQTQLAAARALAAELAVAYSSNCGHRGNIGLERLDDVV
                     AVRSRLAELATLAKHELLSFMPGGGQSEDALNASRPLDEHSLAAGVRIRTLYLDSVRND
                     RATMEYARWLSGLGGEIRTIPSLPVRLLIVDGTQALLPVDPENSRAGAVVVHAPGVLAA
                     LVSLFESYWERARPLGAVESAEAGEPTAQELELLRLLETGSTDEVAARRLGVSLRTVRR
                     MMAEIMSKLGARSRFEAGLLAARCGWL"
     misc_feature    28081..28093
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.37"
                     /tool="antismash"
     gene            28088..28375
                     /locus_tag="NRO40_RS23760"
                     /old_locus_tag="NRO40_23760"
     CDS             28088..28375
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS23760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NRO40_23760"
                     /product="hypothetical protein"
                     /protein_id="WP_157901873.1"
                     /transl_table=11
                     /translation="MEHFYAHRPPAVAETGPSGAGGVLYVLGGSLEVAGNGALAAVRRV
                     LDGVPASAALETPAHRWVTGLCDATVRVGFDRHRGAAPAGAGERQESLPS"
     gene            complement(28354..29013)
                     /locus_tag="NRO40_RS23765"
                     /old_locus_tag="NRO40_23765"
     CDS             complement(28354..29013)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004937654.1"
                     /locus_tag="NRO40_RS23765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23765"
                     /product="HAD family acid phosphatase"
                     /protein_id="WP_058942532.1"
                     /transl_table=11
                     /translation="MHAPGRARRWSAALAASAALTLALPAQATAAAAAEPAERRAAAVA
                     THGGLAQLRGVDYTAWQRDVATALTSARPYLEQRTAGGSGQKLAIVLDIDNTSLETDFH
                     YFWEYPTPAVRPVLDLARYAHSRGVAVFFVTARPGIIHDLTAHNLKAVGYPVTGLYVRD
                     LPDLFEEVAAYKTEKRAEIEAKGYTVIANIGNRPSDLTGGHAERTFKLPDYDGKLS"
     gene            29152..29778
                     /locus_tag="NRO40_RS23770"
                     /old_locus_tag="NRO40_23770"
     CDS             29152..29778
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890206.1"
                     /locus_tag="NRO40_RS23770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23770"
                     /product="nucleoside/nucleotide kinase family protein"
                     /protein_id="WP_058942531.1"
                     /transl_table=11
                     /translation="MDAHRLAVLTTRARQLASTGPRRILGLAGAPGAGKSTLAARLVDG
                     LDGLAALVPMDGFHLAQAELERLGRAARKGAPDTFDAAGYAALLARLRAPEPGVTVYAP
                     AFDRDLEEPVAGSVPVPPDLPLVVTEGNYLLHDDPAWAPVRALLDEVWFVETDDRLRVR
                     RLVERHVAHGKDRARAERWVRESDEANARLVAAGRDRADLVVHLA"
     gene            30087..30959
                     /locus_tag="NRO40_RS23775"
                     /old_locus_tag="NRO40_23775"
     CDS             30087..30959
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642268.1"
                     /locus_tag="NRO40_RS23775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23775"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_058942530.1"
                     /transl_table=11
                     /translation="MDPDLLRTFVTVTRLGSFSAAAHELGRDRSAVARDLADLERDLGL
                     PLLTRRPVVPTVAGARLLEHAVPLLLRLGAARADLARLAAAPDAELAVAASPLAVGPRL
                     LAALPTATARVTLTVLPREAVRAALAAGAAVLGLVDRLDVPGDPADDGPEAAEPTATRV
                     ATAPLALHLPAGDPLAHRSGVRLGDLAAARWIDAPAAGIPLDRLRAAHGTYGFRPALRY
                     DGTDVRTLTALAAAGRGLALLPETVPAAPGATAVPLVEPRLVHRVELLRAAAPAGPAAE
                     LADRLTRAR"
ORIGIN
        1 gggccgccac tacgcccaca acgccgccgc cgcgctcgcc gccggcgccc gcgtgggcat
       61 cgacccggcc gacctggccc gggccctcac cgcctacacc ggcgtcggcc gccgcctcca
      121 gctcaagggc gaggccgcgg gcgtgcaggt cgtcgactcc tacgcccacc accccaccga
      181 gatgaccgcc gacctggagg cgatgcgggc cgcggccggg accggccggc gcctcctggt
      241 ggtcttccag ccgcacctgt tctcccgcac ccaggagctc ggcacggaga tggggcaggc
      301 cctcgccctc gcggacgcct ccctcgtcct ggacatctac ccggcccgcg aggacccggt
      361 cccgggcgtg accagcgctc tgatcagcga cgcggccacc gcggcgggcg ccgccgtcac
      421 accggtccac gacaaggcgt ccgtccccga cctggtcgcg ggaatggcgc gccccggcga
      481 cctcgttctc accatgggcg ccggcgacgt cacggacctc ggcccgagga tcctcgcccg
      541 cctggcggac tgacccgagc agagggagct gagcacacca tggcgtacga ggtcgacaag
      601 ccggacgagc agtggcgcac cgagctgagc ccgcaggagt accacgtcct gcgcgaggcc
      661 ggtacggagc ccgccttcac cggcgagtac accgacacga agaccaaggg ggtctactcc
      721 tgccgcgcct gcggggccga gctcttcacc tcggagacca agttcgcctc gcactgcggc
      781 tggccgtcct tctacgaccc gaaggacggc gccgccgtcg agctcgtgga ggaccgctcg
      841 tacggcatgg cccgcaccga ggtgcgctgc gcccggtgcg gctcgcacct ggggcacgtc
      901 ttcgagggcg agggctaccc gaccccgacc gaccagcggt actgcatcaa ctccgtctcg
      961 ctgcggctcg cccccgacga ggggtgaccg cggcgcgccc ggtgacgggc gggtgacgcc
     1021 tccccggtgg cggtcgcgcg gcgggtgcgc ggcgggtgtg cggccacagg cgtgcgggcc
     1081 ggggcccgcg cgcggcggcc gcgccgcctc agtcgtgggc cgccgccccg ggccgggccg
     1141 ggaggccgcc cgccgcgtgg acctcctcca cgggccgcgc ctccgcccgt ggcgcgcccc
     1201 acgcctccgc cgcgcggacc gccgccgcgg cctgcgcgcg ccccatcgcc ccccagccca
     1261 gcaggtccac cgcctgctgc ggcgtgacga gcagacgggc gtaccggatg ttcagcgccg
     1321 ggtcgacggc cgaggggccc atcccggtca gcggggcggc gaagcgggtc ctggccaccg
     1381 gccggccgtc gtgcacgtcc ggcaggtggc ccaggtacac gggttcgccg gtggtcacgg
     1441 acgcctcctc gccggcctcc cgcaccagcg ccgcggccgg tgacgggtcc tgcggctcga
     1501 tggtcccgcc cggcagctcc gcgtggccgt cgcgcgggtc gaccagcacg agcacccgcc
     1561 cgtcgggcgc gaagagccac ccccacgcct gacggggcgt caactgcgtg ggtacgggcg
     1621 tcccctcgta ccagggcagc tcctgcgccg tcctcggccg cccgaagagc cccagccggt
     1681 ccaggaccgg ggccggcccg gcgggcctcc cctcctccag caccaccggg cccgcgccgg
     1741 cgacgcgcgc ccgcagcgcg gccagcatcc gccgcccctc ggccgccggc agcagtccgg
     1801 ccgcgacggc cggctccacg cacgtgaccg gcccctccac cccgccgagt ccggcggcgt
     1861 cgaggcgacc gccgtcgacg acgagccgtc cctcgcagcc ggccgccacc cggtcgaaga
     1921 ccaggaccgg ccgcgcgggc accgtgccgc acggcaggga cagggcgcag ccgcaggacg
     1981 gcagcgccca cgggccgccc ccgcccgccg gccgtaccag cagcggtcgc gcgcgctcgt
     2041 cggtcaccag cacgccgacg gtcgaccgca ggacggacgg ggggtggggg gtctcgagca
     2101 cgggccggct ccagggtctc gtcgtggcgc ccgaccgccg ccggagcggc gaccggccgg
     2161 gaccgctcgc ggtgcgggcg cgggggcggg tgcggtgcga gggggcggtg ggggtggtgg
     2221 gcgcgatggg tgcggtgcgc ccaagatcgt aacgccacag gggagttgac ggaacggcct
     2281 gcgacacctg ccgggcccgc ccgcacaccc cccgaccctg gcatcttgat gcagtggcac
     2341 cttacggcca caagggcgct ctggagagtc cccgcgtggc cgtgccattt tgaacgggcg
     2401 gctaccgggt gaattcccgg gggacggcac aggaagtccc gccgccgaac gcacccactg
     2461 tcgtgccaat gccttggacg aacgaggacc atccatgccg accagattca tcgctgctct
     2521 cgcctgctcc acggccgcgt gcgtcgccgt gttgatcgtc gaccccgcga agcggaccga
     2581 tgagctccag tcctcttccg tctcgaatgt cgtcgagaac tccgaggaca gctggggctg
     2641 ggactgaaac accgaacggg gggacgtctg atggaagacc gggaacgact ggccgcggac
     2701 ctcgcggagc tgccccggct gtacgccgag atggagtacc tcatggggcc ggtcgccacc
     2761 ggcccccttc agcgggtcag tggcaccagg agcaccgacc gcgtcttcga cgaggccgcc
     2821 gcggcggccc gctccgccat cgtgggcgtg ctcgcctcgt gggccggtgt ggcggtcgag
     2881 acctacgggc cgcccgtgcc cgagcgccgg gtgcccgagc tcgccgcgtt cctcgcccgt
     2941 cacctcgacc tgctcgcaaa ccacccggcc gtcgccgaca tggccgggga gatcgcgcag
     3001 gtcaccgacg gggcgaggcg gatcgcccgg ccggacggcg tccgccgcat ccgggtcggt
     3061 gcctgcgtca gggacgggtg cgggggcgag gtcgtcgtca ccatgggcgg cggcgccgac
     3121 gggtgggcgc gggacgtccg ctgcggggcg ggccacgtct ggcagccgca cgagtggctg
     3181 gacctgcgcg gccggatggc cgcggcggag cccgcgcggg cggcccgccg gacgctgccc
     3241 acccggctcg ccgccgtcgc cgtcggggtc tccgaggcga ccgtgcgcaa gtgggccagc
     3301 cgcggcaagc tcacccgcca cggcacggcg acccgcgccg aatacgacct cgaagaattg
     3361 accctgctcg ccgccggata gcgcgggaca ggaatccacg cagccgaatg cgcgcatgaa
     3421 ttgacatccg ttcatgcgcg gattcggcat gtccgcattc gtggaaaagc ggttgtggat
     3481 catgtttgac aagggcgtgg gcgggtgtca cgctggggcc agcggaagaa gtgtcggaat
     3541 ttacggaccg acccgcctcg aactcctgat atcggcaccg ccggtgcggt cgaccgccga
     3601 ggcgcatttc tccggatcag catcggatcg ccgattgggt acggtcatga ctctggactc
     3661 ggacgacgcc accctgaaat ccctcgagga gatcgagcgg gcgcgggccg cctgggagga
     3721 ccgcccccgc cattcctcgc ccgacgccgc gtaccgcgct ttcgtcgacg agctccgcag
     3781 ggacgtcccc ttctaccggg acgcgggcgt ggaactcccc ctgacggacc gggcggtaca
     3841 ccaggagaac ggcgagctgt tccgctcgcc gcgcgtcgcg gcgacgtacc ggctctcctc
     3901 cagcgggacc accgggaagc cgctcgaagt gaggctcgac gacgccgcct ggtacgccgt
     3961 caattaccgt ttcttcgcgc agatacggga cgtcgccggg ctccccgccg acctctttcg
     4021 gcgcggtgag ccggccgtcg tcttcatcag caacaagccc ggccgcgcca gtttcgtccg
     4081 cccgctcccg cccctgggca acggcctgta cgtacgcctc caactcggcg gcgccgacgc
     4141 gctgcggctg ttctcccggc tccgcgcgcc ggtgctctac gggaagccga cgtacctgct
     4201 cgacctgcgt gccgccctgc tccggcaggg cgcggccgaa ccgccctgga cgccccggct
     4261 gctgctcgtc agcggcgagc ccctgcacga cgacgaccgg cgccgcctca ccgactactt
     4321 ccgggcaccc gtcgtggacg ccctggcgtc gaccgagggc ggcctcgtcg ccgccaccac
     4381 gcccgacgcg cgcacctacc gggtcttcgg cgagaacgtc cgcctggagg tcctggacga
     4441 gcacggcgcg ccgcgccccg ccggagcggg cgagctggtg ctgaccaacc tcgtcaaccg
     4501 cggcaccttc gtcgcccgct accgcaccgg cgaccacgcc gaactggaca ccgcccccga
     4561 cggcacccag cggctgctgc ggctgcgcgg acgcgagccg gggaccctgc ggttccgtac
     4621 ggcggagctg cccgccgaga cggtgaccgg cgccgtcggc cacctgcccg ggctcggcga
     4681 cttccaggtc gacctgcgcg acccggaccg gaccgtgctg cgctgggccc ccgagcccgg
     4741 ccgccccgac gaggaggggc tccggcggga gctgcgcgcg gccctggacc gcctgctgcc
     4801 gggcgaggag ccgctgctgg agcgccacga gcggatcacc ccgcccgggg gcaagaagcg
     4861 gcgctacctg accgcgcccg cgtgaccccg cccgcccgcg gaccgggcgc cgccggcacc
     4921 gacggcaccg acggcaccga ccccgcgacc atcccgtcgc ccagcgaccc cacccacacc
     4981 cggcggaagc gaccgacccc atgacgcgag acctgacctg gacgggcaac cacttcctgg
     5041 accccgccgc ccacaccgcc cggctgctcc gggcggccga ggacatcgac atcaccaaca
     5101 aggacgaggt gtggagccgg caggtggcca cggccgccgc cgcccacttc ggcgtgcccg
     5161 ccgacttcgt ccgcgtcggc gccggcgcca cccagctcat cgacaccctg ctgcgcagcg
     5221 cctaccgcgg gctcgtggtg gacgtgaccc ccaacttcca cctcaccgcg accgtcgccc
     5281 gccagcaggg ctgggagtac ctcgccgtcc cggtgcgcga acccggggag ctgctccccg
     5341 cgctggagcc ccacctcggg cgcgacgacg cgatcaccgt gctgtgctcg ccgcgcaacc
     5401 cgctcggcta ccagttcccg gtggaggacg tcgccgcgct cctcgagcgg gcgcggggcc
     5461 tggtcgtcct ggacgaggtg tacgcggact tcgccccggc gaccgcgctg cccctggtcg
     5521 agcgcttccc gaacctggtc gtcatgcgca ccttctccaa ggcgtggggc ctggcgaacc
     5581 tgcggatcgg cttcgccgtc tccgcctcct tcgcccgcga ggacttcccg ttctggctca
     5641 tgccgaacag cgtctcgggc gtcgcccagc gcaccgcgct cggcctcctc gccgatccgg
     5701 cgccggtccg cgacagcgtc cgccgcgtgc acgcgtgccg tgagcggctc gtcgccgggc
     5761 tgagcggggt ggaggggctg cgcctgtggc cgtcggacgc caactacgtc tgcctggaga
     5821 ccccccgggc cgccgaggtc gtcgaggagc tgggccacgc cgggtaccgc acgcggctcg
     5881 tccacgacct gcgcggctac cccgccgact ggccggccgg cgtgcggatc gtcgtcccgc
     5941 ccgagcccga cgtggaccgc gtcgtcaagg gcgtcctcca cgcccaccag gggcccgggg
     6001 ccgcgccggc gccggcggac cggtgaccgg cggaccggcg cgcgccaccg gcggggcggc
     6061 caccggcggt ggcgcggggc ggaccgacgg gccgccctcg ctcagcgccg acgggcggta
     6121 cgccgcctgg ctctccgccg gcgacggcgc cacccgcctc gtcgtgcacg acctcgcggc
     6181 ccggcgcgaa cacggccgct cggacgtcgg agccgcccgc tgccgcgcct tcacctggtc
     6241 gcacctgccc ggagtcggcc tcgccctctc cgacccggac ggctccgaga gctggacgct
     6301 cttccgcgtc gacgtggcgg acggcacctg gacgccgctc ggcgcgccgg ggcggcgcac
     6361 acggctggcc ggactgagcc cgcagcgccc cgaggaggtg ctgctcgccg ccgagggggg
     6421 cgagcccggc cgactcgacc accacctggt gtccctgcgc accggcgccc ggacggaggt
     6481 gctccgcgac cgcggctacg cggccgtcta cgccgacacg tccctgcgcc cccggctgac
     6541 cgagaccgtc ggcgacgacg gctcgcgcga cctgtggcac ggcgagccca ccgccggccg
     6601 gccgttcctg cacgtcccgc acgaggacgc gctcaccgtg cggttcctcg ccttcgcacc
     6661 cgacggggac accgcgtact tcgtcctgcc cgacggcccc gacggcgtcc gcctcaccgc
     6721 cctcgcctgc cgggacggcg cccccgcgcg cgagctgcgc accgagcacc gggtgcgcgg
     6781 cggggacatc ccggacgtcc tgttcgagcc cggcaccggc cgcccgggga tcgtgcagac
     6841 cgaacgcgag cggcgcgcct gcgtcgccct ggacccccgc tgggcacccg tactcgagca
     6901 cctgcgcacg cgcctcggca ccgaacccgt ggtcaccgag cgccgcggcg gccggtggct
     6961 ggtggccgcg caccgccccg agcacgacac gcactggtac gtccacgagc ccgccggcgg
     7021 cgacacctgg cggctcggcg cggcccggcc cggcaccccg ccatcgtccg tcacgtgccg
     7081 cgccgtcggc gtgccgctgc gcggcggcgg cgaggccgtc acgtacgtca cgcgcggcac
     7141 ggcacgcggg gacggcgacg ggcccggccc cgccgtgctg ctcgtccacg gcgggccctg
     7201 gcggcgcagc cgctgggagt acgccgagcg gcgcacctgg ctcgccgagc ggggctgcac
     7261 cgtcatcgag cccaacttcc gcggctccac cggcttcggc ccggcctgga ccaacgccgc
     7321 cgaccggcag tggggcctgg ccatgcagga cgacctggag gacgccctcg actgggcggt
     7381 cgccgagggc gtcgccgacc ccgaccggct cgccctggtc ggcggcagct acggcgggta
     7441 cgcggtgctc cagatggcgg ccaccacccg ccgggacctg cgctgcgtgg tggcgacctc
     7501 gcccctcacc gacctggtgc gcttcctgga ggaacccccc gccttctggc ggaccgccgc
     7561 gcccatgctg caccgccgcg tcggggaccc cgccgacccc gaccagcggg cggcgctccg
     7621 ggcggtgtcg ccggtggaca acgccgccgg cgtgcgctgc cccgtcctgc tcgtccacgg
     7681 cgccaacgac agccgcgtcc cggccgagat ggccacccgg atgttcatgg cgctggcccg
     7741 ggcgggcaag gacgcgaccc tcgcgctctt ccccgacgag ggacacgagg tggtcaccac
     7801 cggcaaccgg gccgcgctcc acgccgtgac ggccgcccac ctcgacacgc acctgttcga
     7861 ccgcccgccc gccgccgacg cgggcccgcc cggtgacacc accctcaagc tcttcgacac
     7921 accccacgcg gcgcgccgca aggcggcgtc cgcgcccgat cctggagacg tccatggcac
     7981 tgcacttcac gcgcagtaac gcgctgctgc tcctgacccc gaagacgggc agcacgtgga
     8041 tccgcaggaa ggtcagggaa ctcggcctgg aggtcgccga ggtcggcgac ccggcgatgc
     8101 gcgagcacga cctcctcgcc gacttcgacc gctcccggta cggcttcgtc ggcgccttcg
     8161 tccgcgaccc gctcgagtgg taccgctcct actggtccta ccgcatggag aagggctggc
     8221 ggccgcagta cccgctcgac gagcactgcg agagcgacga cttccagacc ttcgtgcggc
     8281 gggccgtgac cgtcctgccg ggcgcgctcg gcaacatcta cacctcgtac gtcggcacgc
     8341 cggacgacga ggtggacttc gtcggccggc aggaggacct ggcagccgac ttcgcgcggt
     8401 tcctgaagct cgccggcgag gagttcgacg cctccgtcct cgccgagggc gaccggatca
     8461 acgcgaccag catccgtccc gactacccgg aggagctcaa ggagctcatc accctctccg
     8521 agtgggagac catggcgcgc ttcggctacc tcgacgcccg gcccgacccg atcggcctcg
     8581 ccgagatgcg cgcccgctac cccgaggacg ccggtgacct gcggctgctg tccctgtgga
     8641 ccgagaagat ccactgggcg ccggacgacg tcaagcgggc ctcgggccgg ccggtgcgcc
     8701 ccgagacccg gtacgcccgc gtccacagca acttcgcgct cttcgcccag cacaagaagc
     8761 aggaccccga gtacgccggc acccgctacc gcgaggcgct gcgcctcgac ccggcccacc
     8821 cgcgcacgct gtgcaactac gccctgtacg tcgccgagca cgaggacgac acggccggcg
     8881 cccgcgcgct gatgctgcgg gcgctgtcgg gccgcccgaa ccacccgtac accctcggca
     8941 agctggcgaa gctgaccgcc gagcggctcg acgaccccga cctcgcggag gtcctctacc
     9001 ggcagagcct cgccgccaac agcgaccagc gggagctgcg cgccgagttc gcccggttcc
     9061 tcgcgggccg cggcaagacc gacgaggcgg tggccctgct cgcggaggag gccgagagcc
     9121 cgcgggccga ccggctcacc ctgctcaccc acgcgtcggt cctggcccgc gccggccgga
     9181 tcaccgaggc ccgccgcttc cagcagctcg ccgccaccgc cgcctgagca cgaaaaggag
     9241 aacgaccatg acgatcacgg aggaccggct cgcccggacc atccaggacg agtccgtgtc
     9301 cgcggccggc cggacggtcg cgcagaccgt cgccgcggcc cgcgaggtcg tcgggcggaa
     9361 caggatctgc ctggtccgcg acttccccct ggaccccgac cgttacctgg agttcctcgg
     9421 cgccttcggc gaaccgctgc ggaactactc ctcgctcagc gagctggcga agaccgaccc
     9481 gcacccgcag atcaaccggg tgaagtacaa gaagaagacc gagggcgccc agtccgtcca
     9541 ctacgtcgcc ggcggtctgc ggccgcactc cgcccgctcc tggtgcacgc cccgcccggc
     9601 gttcttcgcg atgctcatgg tggagcccgg ctggcgggag gtcccggccg ggcagcgggg
     9661 cgagtccgtc gtggtctcct ggtacgacct gttcacccgg ctcgccgagc gggacggcgc
     9721 cgtgttcgag gagcacttcg cgcggctgtc gggcacgccg atcaccttcc gggccaacaa
     9781 cgtgcgggag gagctgagcg acctgccgct gctctacccg ctggacgact cccgcgggcg
     9841 gtacgacgtg ggcgtccggc tcaagcagga cctgcgcgac aagatcgcgg gcatcgagga
     9901 ccagctgccc gacgccgacg cctaccggaa gtccctggac tacctgctgg acgccagcgt
     9961 cgaggacggg ctgttctcct gcttcccgat ggagcgcggc gacctgctgc tgctggacaa
    10021 ccaccggttc gcgcacggcc gtcagaagat cgtcggcgag tacgcggtcg acggcgaggc
    10081 gcggaccaac gaccgcgagc tgtggagcgt cacggtccgc tgaccggggc gaacaccgtc
    10141 acacccagaa ggagaagcac atggacaacc ccgtccccac cacccccggc gaggacgcgg
    10201 ccgagccgac cgggcaggcg gccgagcagg ccgacctggc cgccgtctgc gccgagctcc
    10261 agggcgagct cgacgcgctg atggccggcc ccgggacgaa cgcggcggcg cagtcgctcg
    10321 acacggccgt ctcgtcgctg aaggaggtcg agcagcgcaa cgtctcgtcg gtgcagctcg
    10381 tggcgctcgc cgaccggtag gcggacccgc tcccaccgcc ccgcgccggg gcggtgacac
    10441 cgctccgccg cggtggtgac gcctccccgc cgggcccccg cgggcccggc ggggaggcaa
    10501 ttcccggcac tgttcccggc ccgtagaatg gccgcggccg agggctgtac ccggtgtcat
    10561 agagaaagtc agagtcgtca tgtcattgac cggaaagcac attctctcca gcgacctctt
    10621 cacccgggac gacctggagc ggctcttcga actggcggac gtcctgacgc cggtggcccg
    10681 cggccggaag gtcacgcggg tcctcgaggg cgccgtgatg gcgagcctct tcttcgaggc
    10741 cagcacccgc acgcggctga gctgcgagtc ggccttcctg cgcctgggcg gcggagtgac
    10801 gacgaccacc ggggtcgagc tgctgtcgat cgccaagggc gagtcgctgg ccgacaccag
    10861 ccgcgtcgtc agcggctact gcgacctcgt cgtgatgcgc caccccgacg aggcggccgt
    10921 ccacgagttc gccgacgcca cccacgtccc cgtcgtcaac ggcggcaacg gcgcgggcga
    10981 gcaccccacg caggcgctcc tcgacatgtt caccatgcac cgcgagttcc accgcctcgg
    11041 ccgcgacatc gacggcgccc ggatcgccat ggtcggcgac ctccgccacg gccgcaccgt
    11101 ccactcgctg atcaagctgc tgtcccggta cgacaagctg acgctggtct gcgtctcgcc
    11161 cgacagcctc ggcatgcccg ctccgctgct ggaactcgcc gcgagccgcg gccaccacgt
    11221 cgaggtgagc gaccggcccg aggccggcct gcgggacgcc gacctggtgt acgcgacgcg
    11281 cctgcagacg gagcgcttcg ccgacctgcc cgtcccgtac agcgacgagt tccgcatcga
    11341 ccgcgcgctg gtggaccggg tctgccgccc cgacacggtg atcatgcacc cgctgccccg
    11401 ggacagccgc cccgccgcca acgacctcgg cacggacctg aacaccgacc cccggctggc
    11461 gatcttccgg cagaccgacg cgggcatccc gatccgcatg gcgctcttcg cgtcggtgct
    11521 gggcgtcgcc gacgccatcc ggccctcgct gcgcccggcc acctggtacc ggccggactt
    11581 cacgggcccc gacgacgccc ccttctaccg caacaccgcg gtggagggca tcgcgtagcc
    11641 gacagacacg aaccacccag acgaacgccg aagcgggccg gagacctccg gcccgcttcg
    11701 gcgttcccgc gtccgagcca agaggaattc catgagtggt gagacgcgcc gcgagaaacg
    11761 ccgacgggat ttcgccgcct accggcatcc gatcgtcgcg gtgacgatgg cgagcacgtt
    11821 cttcctgaag ctcgtgtcgt atctctgtat tccgttcatg acgatcttcc tgagccgcaa
    11881 cgccgacctg ccggcccacg tgatcgggct gctcgtcggg ctcaaccaga tcggctcgct
    11941 gaccgccggc ttcttcagcg gcgtcctcgc ggaccggatc gggcggcggc ggatcctgct
    12001 cgtcgggctc ttcggcaccg cgctggtctt cgggctgctg ttcgccgtgg ccacgtacct
    12061 gcggcagtcg ctggcgttcc ccgtgctgtt cggggtgctg aacgtctcgt acggcgtgat
    12121 gtcggcgttc ttctggccgg tcacccaggt ggtgatggcc gacagcctgc cgaaggagca
    12181 gcggccggtg ctcttccgcc accggtacgt gctgacgaac acggccgtgg ccgtcggccc
    12241 gccgaccggg gccttcctgg ggctcgcctc cgaccggctc gccttcgtca tcgcgggcgg
    12301 ctgctacctg ctcttcgcgc tcgcgtacgc gtggctcggc cggggcacgg agtacggcgc
    12361 ccccgtcccg acgcccgccg cctcggcccc cgcggcggga gccaaggcgg cgggggaccg
    12421 gcgcagcttc accggggcgc tgcgggtgct cgcggcggac cgggcgttcc gcagcctcac
    12481 cgtgtcgatg atcctgttca ccctggcgta ctgccagatc gagtcgaacc tctcgcggat
    12541 cgtcagcacc gggttccccg acgggatccg cttcttcgcg gtgctgctca cggtcaacgc
    12601 cgtggccgtc atcgcgctcc agccgcttgc ctcccgggcc gccgagcggc tgggcccccg
    12661 gcgcaccctc ctcacgggca acgcgctgtt cgcggtcgtc tgcctgctgt tcccgctcac
    12721 cggctccggc cgggcggccc tcgtggcgct ggtcgtgctg atcagcctcg ccgaggtcct
    12781 ggtcgtcccc acggtgagcg tcgtggtgga cgaactcgcg ccacccgacc tgcgcggcac
    12841 gtacttcggt gcggccacgc tccgcaacct cggtctcggc ctcgggcccg cggcgggcgg
    12901 gctcgtgctg acgctgttcc cccgggaact gctcttcgtc ttcatggggc tgtgcgccgc
    12961 cgccgcgtgg gccgtcatcc acttcaccct cagggagaac gccggtgcgc atcctggtcc
    13021 tgcatcagaa cctgtttgaa cggctcgcct acgagcgggc catcgaccac tccgtccacg
    13081 acgtcgtgta cgccgggacg ccgcagtacc tcgccaacat ccccgcccat gtccgctgcg
    13141 ggacgttccc cctggacccg gcccggcccg tcgccgacca gctgcggccg tggatggccg
    13201 ggcagccgcc gttccagcgg atcatcgccc ggcacgagaa gctgatcacc ccggccgccg
    13261 agctgcgcga cgccttcggc atccccggca tgggcgccgc ggcggcgcgc aacttccgcg
    13321 acaaggtgac catgaagcgg accctggcgc gggccggttt ccgcgtgccg cgcttcgtcc
    13381 ccgcggaccg gccggcagcc ccggacggtc cggccgcccc ggaccggccc ggcgccggcc
    13441 ccggctggcg cggccggacc atcgtcaagc cgcgcgacga gggcggcagc cagggggtac
    13501 gtctcttcga gaccctcgac gaggcgctgg agttcgtccg cgccgccgcc gcgcagtccc
    13561 ccgcggaccc ggccgcgcag accggcacgg agcagggcac gggcggcggg ttcgccgccc
    13621 ggtacgagct ggaggagtac gtcgagggcc cgatctggca cgtggacggc ttcctcttca
    13681 agggcgaggc ggtggtggcc cagccgtccc gctacgtcgg cacgccgctg ggcttcgaga
    13741 acggggcgcc catcggctcc gtgcagttcg accacccgga gctgacggag tgggccgtgc
    13801 gctgcgtgcg ggcgctcggc ggcgagacgc tcaccttcca cctcgaagcg atcatgaccc
    13861 cgagcgggcc ggtcttcatg gaggtcgcgg cccgctgcgg cggcgggtac atcgtcgacg
    13921 tcaccgagcg gcgcaccggc gcccacctgc acacgctgga catggcgtcg gacgtggacg
    13981 acgcgctcgc cgagcgcttc ctcggcccgc ccgcacccgg cctcgcgcac ggcttcttcc
    14041 tcttccccgg ccacgtccac ggcggcgcgg ccgtctccgt gcgcggcgcc cgcgccctgc
    14101 tggacgaccc cgtggtggtg cgccaccgga tcaccgcacc gggcacgacc accccgacca
    14161 gccactccta ccggcccgaa cacctgccgc tgtccggcgt ggtccgcggc cccgacccgg
    14221 aggcgctggt gcggtacgtc gaacgggtcc tggagcaggt caccgtcgag gacgaccacc
    14281 ggctggcgca ccggctggcc gaggaggccg gcgagctgct gctgaagctg cgggcggagt
    14341 ccggcttcgc cgacccggcg gcgctgaagg cggcgggcga ccggctgtcg cacgagttcc
    14401 tcgccgcggc gctcgcggcg gagcgccccg gcgacgccgt cctctccgag gaggggaagg
    14461 cggacgcggc gcggctgacc gccgagcggg tgtggatcgt cgaccccctg gacggcaccc
    14521 gcgagttctc cgagccgggc cgggaggact gggccgtgca cgtcgccctg tggaccggcg
    14581 gccggctcgc cgcgggggcc gtcgccctgc ccgcccaggg cgtcacgctg tccaccggca
    14641 caccgccgcc cacgccggac tccccggcgg accgcctgcc cgtcctcggc agccgctcgc
    14701 ggtcgcccgc cttcctcacg caggtcgccg ggcggatcgg cgccgagctg gccggcatgg
    14761 gctcggcggg cgccaagacg gcggccgtga tccgcggcga cgcccgcgcg tacctgcacg
    14821 cgggcggcca gtacgagtgg gactcggccg ctccggccgc cgtcgcgctc gccgccggac
    14881 tgcacgtgtc ccggctggac ggcaccccgc cggtctacaa ccgcgcggac ccctacctgc
    14941 cggacctcct ggtctgccgc ccgcaggacg cggccgccct gctggcggcc gtcgcggagg
    15001 ccacgaccgg ctcctgaccg gtcctcaccg accggaccac accctcaccg aggtcgaagg
    15061 acgatgacgg acacagacaa cagcacattc gaggcggtgc ccgcacaccc cgcgggaccc
    15121 gccggacgcg gcgcgacggt ctggctcacc ggcctcccca gcgccgggaa gaccaccctg
    15181 gcccgcgccc tggccgaacg cctccgcgcc gccggccacc gcaccgaggt cctggacggc
    15241 gacgaggtcc gggagttcct ctcggcgggg ctgggtttcg gccgcgcgga ccgggacacc
    15301 aacgtgcggc ggatcggctt cgtcgccgag ctgctcgcct cgaacggcgt gaaggtcctg
    15361 gtgcccgtca tcgccccgta cgccgacagt cgcgccgagg tgcgcgcaca ccaccggcgg
    15421 gagggcaccc cgtacgtcga ggtgcatgtc gccacgccgg tggaggtgtg ctcggagcgg
    15481 gacgtgaagg ggctgtacgc ccggcaggcc gccggcgaga tcagcgggct gaccggcgtc
    15541 gacgacccgt acgaggagcc cgacgccccg gacctgcgcc tggacacggc cggccggccg
    15601 gtggccgggt cggccgcgga catccacgcc ctgctcgtcg gaaggggact ggcatgagtg
    15661 ccgtgaccgg ggcgaccggt gtctaccgcc ccacccacct ggacgtcctg gagtccgagg
    15721 cggtgcacat cttccgcgag gtggcgggtg agttcgagcg gccggtggtc ctcttctccg
    15781 gcggcaagga ctccatcgtc atgctgcacc tggcgctgaa ggcgttctgg cccgcgccgg
    15841 tcccgttctc gctgctgcac gtcgacaccg ggcacaactt ccccgaggtc atcgagtacc
    15901 gcgaccgcac cgtcgcgaag cacgggctga ccctgcacgt cgcacgcgtc caggagtacg
    15961 tcgacgacgg ccggctcacc gagcggcccg acggaacccg caaccccctc cagacggtgc
    16021 cgctgctcga cgcgatcgaa cggcaccgct tcgacgcggt gttcggcggc ggccggcgcg
    16081 acgaggagaa ggcgcgcgcc aaggagcggg tgttctccct gcgcgacgag ttcggcgcct
    16141 gggacccgcg ccgccagcgc cccgagctgt gggacctgta caacggccgc cacatggtcg
    16201 gcgagcacgt gcgggtcttc ccgctgtcga actggaccga gctggacgtg tggcagtaca
    16261 tcgagcgcga gggcatcgag ctgccggaga tctacttcgc gcacgagcgc gaggtgttct
    16321 cccggtccgg catgtggctc accgccggcg agtggggcgg tccgaaggag tccgagccgg
    16381 tggagaagcg gatgatccgc taccgcacgg tcggcgacat gtcctgcacc ggcgccgtcg
    16441 actccgacgc caccaccgtc gccgacgtca tcgccgagat cgccgccagc cgcctcaccg
    16501 agcgcggcgc cacccgcgcc gacgacaagc tgtccgaggc cgccatggag gaccgcaagc
    16561 gtgaggggta cttctgacat gacggccacc acccacaccc ggcacgaccc cgcggcggcc
    16621 accctgctgc gcttcgcgac cgcgggctcc gtcgacgacg gcaagtccac cctggtgggc
    16681 cggctcctgc acgactccaa gtcggtcctc gtcgaccagc tggaggccgt cgaggcggcc
    16741 tcccggcgcc gcggccagga cgtcccggac ctggcgctgc tcacggacgg cctgcgggcc
    16801 gaacgcgagc agggcatcac catcgacgtc gcctaccgct acttcgccac cccccggcgc
    16861 cggttcatcc tcgccgacac ccccggccac gtgcagtaca cccgcaacat ggtcaccggc
    16921 gcgtccaccg cggacctcac cgtcgtcctg gtcgacgcgc gcaacggcgt cgtcgagcag
    16981 acccgccggc acgccgccgt ctccgcgctg ctgcgcgtcc cccggctcgt gctcgccgtg
    17041 aacaagatgg acctcgtcgg ctacgacgag gcggtcttcg cggccgtcgc ggacgagttc
    17101 accggctacg cgcgccgtct cggcaccgcc gacgtcgtgg cgatcccgct ctccgcgctg
    17161 gagggcgaca acgtcgtcgc cccgtccgcg cacacggact ggtacagcgg tcccaccctg
    17221 atggagcacc tggagggcgt cgaggtcgcc gccggctcgc cggacgcgcc cgcccgcttc
    17281 cccgtccagt acgtcatccg cccgcagagc ggcgcgcacc gcgactaccg cggctacgcg
    17341 ggacggctgg cgtccggcgt gctgcggccc ggcgacaccg tgaccgtcct gccctccggg
    17401 cagcgggcca ccgtcgccgg catcgacgtc ctcggcaccc cggcgtccgc cgcgcgggcc
    17461 acccagtcgg tcaccgtccg gctggccgag gacgtcgacg tctcccgcgg cgacctgatc
    17521 gccgccggcg ccgcgccccg gctcacccgg gacgtcaccg cgaccgtctg ccacctccac
    17581 gaacgccccc tgcgcaccgg agacaaggtc ctgctcaagc acaccacgcg gaccgtgcgg
    17641 gcggtggtcc gggagatcac gtaccgcacc gacgtcgaca cgctggaacg gcgcgacgcc
    17701 gccggcgccc tggacgtcaa cgacctgggc cgcgtcgtcc tgcgcaccgc cgagcccctc
    17761 gccctcgacg actacgcgga caaccgccgt acgggcgcct tcctcctgat cgacccggcc
    17821 gacggcacca cccgctcggc cggcctggtc ggggagacgt ccgcctgggg ggcgccgtga
    17881 ccgacgtcga cctcttccgg ctgttcgcct ccctgatgct gctgctcctc gcggcgcacc
    17941 tcatgggcag gctcttcgcg cgcctgcggc agccgccggt catcggggag atcaccggcg
    18001 gcctgctgct cggcccgtcg ctcttcggcc tcctcgcccc cggcgcgcag gggtggctct
    18061 tcccgccgac cgggccggcc gcgaccgggc tcgccctcgt gtaccaactc ggcgtgctgc
    18121 tgctcatgtt cctcgcgggg ctgcagatgc gtgcggtgtt ctcccgtcac gacgggcggg
    18181 ccgtggtgct gatcgccgtc gtcggcatgg tcatcccgtt cggctgcggt ctgctgctgg
    18241 tacgggtcgt cgacctctcc tcggtcgtcg gggaggcggg cgaccacacc gcgctcacgc
    18301 tggtgatcgc gtgcgccgtc gcgatcacca gcatcccggt gatctcccgg atcatgatgg
    18361 acctcggcat cgccggcacc tccttcgccc gggtggtgct ctcggtcgcc gtcctggagg
    18421 acatcgtcct caacgtggtg atcgcggtcg ccctcggcat ggtcggcggc ggcccgcacg
    18481 acgccttcgg cgccccggcg ctgctcgggg tgggcacggg cgacggggcc atcgcctacc
    18541 acgccctcgt ctcggtcgtc ttcttcggcc tgacggccgg ggtggggacg ctcctgcgcc
    18601 gccgtaccgc ggcccgcccg gacgtgccgg cggccggacc ggggccgacc gcgggccggc
    18661 cggaggcggg ggagcggccg ggggcgggcg tccaggtcgc cgtgcaggtc gccgtggtcc
    18721 tcggcgccgg cggcacctgc gtcttcctcg gcatcacgcc gatgtacggc gccttcctcg
    18781 tgggcctgat gacgagctgg agccgcggcg cgggcgagcc cgacccgatg gccgccgtcc
    18841 gcggcttcgc gaccgggttc ttcatccccg tctacttcgc gatcgtcggc ctcaaactcg
    18901 acctggtcca cgccttcgac cccctgctca ccgtggcgtt caccgccttc gcctgcgtgg
    18961 tcaaggcggc cagcgtctac ctcggtgccc gctgggccgg ccggccgcgg gcgggcgcgc
    19021 tcaacctcgc ggtcgccatg aacgcccgcg gcggccccgg catcgtcctg gcgaccctcg
    19081 cctacgacgc gcggatcatc aacgcgaccc tcttcaccac cctggtcctc accgccgtca
    19141 tcacctccct gatggccggc ggatggctcg agtccgcgat ccgccgcggc ctgctgcccc
    19201 gcgacgggga cgaggagcgg ccgcccgtgg cggaccgtac cgacaagatc ccggcaggtg
    19261 cccgatgaac cagcacgcga ccgtctgcac gtgtctcccc ggcgccaccc tgtggctggc
    19321 gcccccgacg gccggtaccg ccccggcgga cgcggcaacc ggtaccgccc cggcggccgg
    19381 tcccgtggcg cccgacgccg ccggtgcggg ccatgccgcc ggtgccgccg cgctggccga
    19441 gcggctgcgc ggcgagcacc gccgcgtcga ggtgctggag gggacggccg ggctcggttc
    19501 gcccggggac accgcggccg ccgccgtcct gcggaccggc ctggtggccg agatcctcgc
    19561 ccgcaacggc atcgccgtcc tcgtgaccgg tgtcgcgccg gacgagtgcg cgctggcgtc
    19621 cgtacgcgag cgccaccggg agggcggggt cccgttcctc accctgccgt ccggtgggtc
    19681 gaccgacgag ctgtacgccg ccctggtcgc caacggcctt ggtgtgcagg cgagttgacg
    19741 gccgaccgac gttcccttct cccgtccaag gggttatgat catgttcgac agcatcgcca
    19801 tcgactgctc ggggatgtcg ccggcggaca tcagggccgc gacggtcgcc tccgtcgccg
    19861 agcaccggct cgcctacctc cgcggtttcc cgctcgacgt cgcgcgctac accgacctac
    19921 tggagcacct gggcgagctc tgcccgaact acgcggccgg ctccgcctcc gacgcgtacg
    19981 ccctccaccc ggccgtcaac acggtccgct gccgggcccc cgaaccgggt ggcgaacagc
    20041 gcgtccagga gaaggccgga tcactgcccc tgcacaccgg gcgctccttc gcccggcggc
    20101 ggccgctcca cctggccatg ctcatggccg accccggctg gcgcgacttc gcaccgggac
    20161 acaacggcga gtccctgatc gtgcgctggg gcgacgtcct gcgcgccgtg cgggagcgcc
    20221 acccggagca ctgggcggag gacctgcgcc tcctcaccgc caactcggtc agcttccccg
    20281 cctcccacct cgacgaggag ccctccgcgc tgcccttcct gtacgtgccc gggacgcccc
    20341 ggctcacccc ggtgccggac gacgtcgccg tgcgcctccc ccaggacgtc acccggctgg
    20401 gccgggcggc cgagcggatg ccggacgggg agcgctggta cgaggccgtc gtgcggttca
    20461 aggccacggc cgacgacccg gaggtgcacc aggcgtacgt catggaggcc ggcgacgtcg
    20521 tcgtcatcga caacgaccgc tacgggcacg gccgccagga ggtggtcgcc acccgcaccg
    20581 cgccggacgg gggcacggcg gtcaatcccc gcaccatctg gagcgtcaac atccagtgac
    20641 ctccgcccgg ccatccctcc ctcccacctc ctggaacagg tcatgaccag aatcatcgcg
    20701 agttgcacgc gcggaaccca cgggctcccg gacgagctga cggccgtcga gggcgtcggg
    20761 caggcgggcg acgtggtcgt cgcccgggtc gtctcggtgg gcgcctacaa ggccgtcgag
    20821 aacaccagcg gccgggacgt ccgcgtccgc gtcggagacg aggtcgtcgg cgtgctcggc
    20881 gagcgccact ccaccacctc gatctacggg gggctgcccg agggcggcct gcccgtgaag
    20941 gccggcgacc cggccgacct gatggcggtc ggcggcatca tcggcatcgc cgcgtcgtcc
    21001 ccgtcctccc tcggcaccgc caccgccctg gagctggtcg gcctggccgc cgaccgggac
    21061 gggcgggtgc tgcggctgcg gcgcaaggcg gccgacacgg ttccggccac gcccgtcgtg
    21121 ttcgtcggcg gcaccgcggc cgaggtcggc aagaccacct tcgcctccgc cctcgtccac
    21181 cacctgaccg cccgccacgg gctgcgggtc ggcgtcacca agctggccgg caccggccgg
    21241 ctgcgcgacc tgctgaccct cgccgacgcc ggtgcccact gcgcggccga cttcgtcgac
    21301 gccggcctcg gcaccacgta cgggcacgga gccgacgccg tcgtcggcgc cgcccgccac
    21361 ctcgtgggcc ggctcgccga cgagggcgcc gagatcgtcg tcgccgagct cggcggcgac
    21421 ctgtggggcg ccggcatccc cgacatcctg cgcgacccgg gcctcgtcgc caccgcccgc
    21481 gccctggtcc tggtgccgtc cgacacgatg gcctccctcg gggtggagac ctggctcggg
    21541 cgcaacgaca tcaccatccc cgccgtccac ggcgtgcccc accgcaacgt catggccgcc
    21601 cgggagcgcg ccgaccgcgg catgggcgtg cagctggtcg acccgcacga cccggacgac
    21661 ctggagcgca tggtgcgcga ggtgctgttc gcgggccggg agccggggga gggcacccgg
    21721 tgagcccggc cgcaccgcac gtcgcgctgc tcctgggcgc cggcggtatc tcgccggacg
    21781 ccgccctgga ggcggccatc acggtcaccc gccaggtcac cgtcgtctgg tacgagggcg
    21841 gcccgacggc cgccgccgcc accgccctca aggagcgctg gagccgggag tgcactggcg
    21901 aatggctcgc caccggcgac caccgcgaga tccccggcat gctcgccgaa ctccaccggc
    21961 ggcgcccgct gcacggcgtg gcgaccttcg gcgaaccgct catcgtcgcg caggccgagg
    22021 cgcaggagct gctgggcctg cccggcaacc cgcccggcgc cgtccgcacc gcccagtcga
    22081 agctggacca gcggcgccga ctgcgcgggg ccggcgtcga gacgatccgc ttccgggtcg
    22141 tccgcgacca gggcgacgtg tccgaggccg tcgccgaggt cggcttcccg gccatcctga
    22201 agcccgtcca cggcgcggcc agcttcctcg tcagcaaggt ccacgacgag gcggagctgc
    22261 gcgcccggct ggccgaggcg ctcaccgcgt accggcagtc gccgctgctg gaccccgagc
    22321 cgctgttcgt cctcgaacag ctgctcgtcg gcgacgagtg gtacgaggag ccgggcttcg
    22381 cggactacgt cagcgtcgag tccctggtgg cggacggccg cgtcacgcac gtcggcatca
    22441 ccgacaaact cccgcagcac ggcttcgtcg agacgggcca cgccgccccc acctccctgc
    22501 cggcccaccg gcagcggcag gtgctcgacc acaccggccg gatcatcgga gccctcggga
    22561 tccgctgggg cgcgacccac gtcgagctca agctcacccc cgacggcccc gcctgcatcg
    22621 agctcaacgc ccgcctcggc ggccccatgg gccatctgct gcgggccgcg accggcgccg
    22681 acatcgccgc ggacgtcgtc aggctcgccc tgggccgccc gcccgagggt gactacggcc
    22741 gggtccgcca cgccctgtac cgctgcgtgc cgccgcccgc cgaaccggtg cggatgaccg
    22801 cgcagacacc gcgcgaggaa ctgctcgcgg ccttcccgga gctggtgttc tgcaagaccc
    22861 ggttcgcgcc gggcgccgag ctccacccgg atcggcccta caacgtcctc accttcctcg
    22921 tcaccggtga cgacatgcgc tcctgcctcg ccaccgcacg gcgggtggag gacgcctacc
    22981 gggctgagtt cgtcccgctc gccggcggcc cgcccgcggc ccgcgcggcc gcgaccccct
    23041 gacgcaccga ccccaccgac ggaaggccga catgcactcc accgccacgg gtgcgaccgc
    23101 ccgcgccctg ctcgacagcc tcgtggacca cggcttcacg ctggccaccg gcgtcccgtg
    23161 ctccctgctc accggggcgt tccgcctcct ggaggacccg ggcgacgacg cccggctcgc
    23221 ccggctgcgc tacgtccccg caccccgcga ggacagcgcc atcggcatcg cctccggagc
    23281 cgtcgtcgcc ggggagcgcg ccgtggtcct catgcagaac tcggggctcg gctactccct
    23341 caacgtcatc acctcgttca acctcatcta cgacgtgccc gtgctgctga tcgtcagctg
    23401 gcggggccac gacggcaacg acgccgtcga gcacgacgtg atcggggcgg agctgctgcg
    23461 gctgctggag ctgttccggc tcccgtacac cgtcctggac cacgccgacc cggccgcctc
    23521 cgtcgccacc gtgatcgacc tgatggacaa ggagcagcgc tgcggcgtgc tcgtcgtccg
    23581 ggaaggcatc tgatgtccgc acccgccccc accccttccg ccgcgctgac gctctccgac
    23641 gtcgccgccg agctcctcga ccggcacccc gacgcggtga tcgtctccac ctgtggtttc
    23701 accacccgcg agctgttcaa cgcggcggac cggccggaga acttctacct cgtcggctcc
    23761 atgggcatcg ccgcgcccgt cgccctcggc atcgcgctcg cccgccccgc gcggacggtg
    23821 atcgccctcg acggcgacgg ctccctgctg atgaacctcg gcgtactgcc cctggtcgcg
    23881 ggcgccggcg tccccctgct ccacgtcgtc gtcgacaacg gcatgcacga gagcaccggc
    23941 ggccaggcca ccgtgggacg cgccgacttc accgccctcg cgctcgccgc cggatacgcc
    24001 cacgccgtcc gagtcgagga cgccgccggc ctccgggcgg ccgacctgac cccgcggccc
    24061 gccctgctgc acgcgctgac cggaccgcgc accggcggcc cggggcgccg ggtgacgcac
    24121 accccgcagc agatcgtcga gcggctctcc gccgcgctcg acccggtcgc cgcctgacct
    24181 cccggaccca ccccacctgt gaaggagttg cccgaatgtc gaagacccgt gccctgcgtg
    24241 aagccctgaa cggccccgcc atagcccgga tcatgggggc gcacggcgcc ctgagcgcca
    24301 agctcggcga ggaggccggc ttcgaggcga tctgggccag cggactggag atctcggccg
    24361 cccgcgccat cccggacgcc aacatcctct ccatggccga gtgcctggag gcggcggccg
    24421 agatcgccgg cgccgtgggg atcccggtcc tcgccgactg cgactccggc ttcggcggcg
    24481 tcggcaacgt cgtgcacatg atccgctcgt acgaggcgcg gggcatggcc ggcgtgtgca
    24541 tcgaggacaa gatgttcccg aagatgaaca gcttcgtgga gggcaaccag gacctcgccc
    24601 ccctcggcga cttcgccgcg aagatcaccg cggccaagga ggcccgcacc gaccccgact
    24661 tcgtggtcgt ggcgcggatc gaggccctga tcgccggggc cggcatggag gaggcgctgc
    24721 gccgcgccgc cgtctacgag cgggccggcg cggacgccct gctcatccac tccaagcaga
    24781 gcgcccccga cgaggtgttc gccttccgcg agtcctaccg cggcgccctg cccgtcatcg
    24841 tcgtgcccac gacgtacccg caggtcaccg cggacgagct gaccacccgc ggcttcggcg
    24901 gggtcatcta cgccaaccag gggctgcggg cgtcgatcag cgccatgcgc gacgtcctcg
    24961 cccagatcgg cggcgccggc tcgacctacg gcgtggaggg ctccatcgcc gcgctgaagg
    25021 acgtgttcgc gctccagcgg gtcgacgagc tgctggcgct ccagcagcgc cacgaccggc
    25081 tgaccgccac ctacgccgcg ccgctcgact gacccggcgc cggcccggcc cggggcgccc
    25141 ccgcgcgcga gccggtccgc cgcccgccgg tccgcccggg ttcccgagcc ccgggcgggc
    25201 cgccccgacg cacgccagac aaaggaagag tatggagccc cgccgtaccg cccccgcacc
    25261 ggccgtcgta gaggtgcgca acctcgtcgg cgacacctgg cgcgacgccc tgtcgggccg
    25321 ccgccaggag aaccgcaacc ccgcccggct cggcgagatc gtcagccgca gcgccgactc
    25381 agacgccgcc gacgtgcgcg acgccgtcgc ggcggcggcc gccgcgctgc cggcctggca
    25441 cgacctgggc cccgtccggc gcggggagat cgtgatgcgc gcggcctccc tcgtccggga
    25501 gcgccgcgag gagttcgccg tggcgatcac ccgtgagcag ggcaagctgc tgcgcgaggc
    25561 gcgcggcgag gtcgaccgga ccgtcgcgct gatggagtac acggccggtg agggacgccg
    25621 gctcggcggg gcgaccctgc ccgccgacga cccgcgcacc ctggcattga cccggcgcca
    25681 ccccatcggg gtggtcggcc tcgtcacccc gtggaacttc ccgctggcga tccccgcctg
    25741 gaaggcggcc cccgccctcg tcgcgggctg caccgccgtc ctcaagccgt ccccgctcac
    25801 cccgtacacc gccgcgctgc tggtggagtg cctgctggcg gcgggggcga ccggcggggt
    25861 gctcaacctc gtccacggcg gccgcgccgc gggcgaggcg ctggtcgccg aaccggccgt
    25921 gtcaggcgtc tccttcaccg gctccgtcga ggtcggccgg gccatccaca ccgccggcgc
    25981 gccccgcttc ctgcggacgc agctggagat gggcggcaag aacgccgccc tggtgctcgc
    26041 cgacgcggac ctcgacctgg ccgccgacgc gatcgtcgcg ggcgccttcg gccaggccgg
    26101 acagcgctgc tcggccacca gccgcgtcgt ggtcgaccgc gccgtccgcg acggcctcgt
    26161 ggcgcgcctc accgcgcggg cggacgccct cacggccggg gacggcctcg acccggacgc
    26221 cgggctcggc cccgtcgtct ccgaggagcg cctgcgggcc tgcgtggacg gggtccgccg
    26281 ggccgtggcg gacggggcgt ccgtcgtccg cggcggcgag cgcctcggcg gcgccctcgc
    26341 cgacggctgc ttcatggccc cgaccgtcct ggtggacgtc gaagcggaca gtttcgtcgc
    26401 ccaggaggag atcttcggtc cggtcctctc cgtcatcgac tgcgacggct tcgaggacgg
    26461 gctgcgcgtc gtgaactccg tgcgctacgg catggccgcg gccgtcttca ccggtgacca
    26521 gagcctcgcc ctgcgggcgc tcgaccgcat cgacgcgggc atgctgcacg tcaaccggcc
    26581 cggcgtcggc gcgtacccgc acatgccgca cgtcggggcg aaggagtccc agtacggccc
    26641 ggccgaatgc tccccgcagg tctgggactt ctacacggag tggcgcacgg cctgcgtgag
    26701 ctactgaccc cggcccgccg tcacggcccg cggtcgtggg cccacgccgc gtccgcgcgc
    26761 tcgatcctcg gaccccctct cggaaccccg cccccagccc ttaccatgca cgctggcgat
    26821 atgatcaagg cactgggggg aaggtgcgtg agcggtgagg cgggtcactg aggcggtcga
    26881 ccactccgac gacgatcctg atcagaggcc actggcgtcc cttctggggc tccacgggcg
    26941 cagtcttgac gtgtaccggc taatcgtgtc ccagccgggg tggggcgtgg ccgagatcgc
    27001 cggcgacctg ggcatgaccg ggccggaggt gcgcgcctgc ctcgacgagc tggccgaact
    27061 gtccatgctg tactcgggcg ggacggcggc cgctccggtc gcgctcccgc ccggcatcgc
    27121 cctcgccgcc ctgctgcacc ggcgggaact ggagatccag gcgcagcaga cccaactggc
    27181 cgccgcccgc gcgctcgccg ccgagctggc cgtggcgtac tcctccaact gcgggcaccg
    27241 gggcaacatc gggctggagc ggctcgacga cgtcgtcgcc gtccgctccc ggctcgccga
    27301 actcgccacc ctcgccaagc acgagctgct ctccttcatg cccggcggcg gccagagcga
    27361 ggacgccctc aacgccagcc gtccgctgga cgagcacagt ctcgccgcgg gcgtgcgcat
    27421 ccgcaccctg tacctcgaca gcgtccgcaa cgaccgcgcc accatggagt acgcccgctg
    27481 gctctccgga ctcggcggcg agatacggac gatcccctcc ctccccgtcc gcctgctcat
    27541 cgtggacggc acgcaggcgc tgctgcccgt cgaccccgag aacagccgcg cgggcgcggt
    27601 ggtcgtccac gccccgggcg tactggcggc gctggtcagc ctcttcgagt cgtactggga
    27661 gcgtgcccgg ccgctcggcg cggtcgagtc cgccgaggcc ggcgagccga ccgcccagga
    27721 gctggagctg ctcaggctgc tggagaccgg cagcacggac gaggtggccg cccgccgcct
    27781 cggcgtctcg ctgcgcacgg tgcgccggat gatggccgag atcatgagca aactgggtgc
    27841 gcgcagccgc ttcgaggcag gtctgctcgc cgcccgctgc ggctggctgt aggcgccctc
    27901 ccggggaagg ccgcctgctg tcatggcagt tagaggccag tcgccctgct gccctcttct
    27961 cggtcgcgat gcgatcatgt tgcgcatgta cgcgatccac atccggttgg attccccagg
    28021 gcagcacggg gtcgccttgg acatcggcgc tgtcgcccag gagcttcagc ggatcccagg
    28081 ttgcactgtg gaacatttct acgcgcatag acccccggcg gtcgcggaga cgggcccctc
    28141 cggggcgggc ggcgtcctgt acgtcctggg cgggtcgctg gaggtggcgg ggaacggcgc
    28201 cctcgccgcc gtccgcaggg tgctcgacgg tgtgccggcc tccgcggcgc tggagacccc
    28261 cgcgcaccgg tgggtgaccg gcctgtgcga cgccacggtg cgggtggggt tcgaccgcca
    28321 ccgcggcgcc gcgccggccg gtgccgggga acgtcaggag agcttgccgt cgtagtccgg
    28381 cagcttgaag gtgcgctcgg cgtggccgcc cgtcaggtcg ctgggacggt tgccgatgtt
    28441 cgcgatgacc gtgtagccct tggcctcgat ctcggcgcgc ttttcggtct tgtacgcggc
    28501 gacctcctcg aacaggtcgg gcaggtcccg gacgtacagc ccggtcacgg ggtagccgac
    28561 ggccttcagg ttgtgcgccg tgaggtcgtg gatgatgccg gggcgggcgg tgacgaagaa
    28621 gacggccacg ccgcgcgagt gggcgtagcg cgcgaggtcg aggacggggc ggacggccgg
    28681 ggtcgggtac tcccagaagt agtggaagtc cgtctccagg gacgtgttgt cgatgtccag
    28741 gacgatcgcg agcttctgtc ccgacccgcc ggcggtgcgc tgctccaggt aggggcgcgc
    28801 ggaggtgagc gccgtggcca cgtcgcgctg ccaggcggtg tagtcgacgc cccgcagctg
    28861 ggcgagtccg ccgtgcgtcg cgacggccgc ggcccgccgc tcggccggct ccgccgcggc
    28921 ggccgcggtc gcctgggcgg gcagggcgag ggtcagggcg gccgaggcgg ccagggcggc
    28981 gctccaccga cgtgctcttc cgggtgcgtg catgggatcc actcctcttc ggatcgggtg
    29041 ggcggctccg ccaccccgtg aatcggcatg ttcgcgtcac atggtggacg gaatgcagcc
    29101 ttccggctac cgatcggtag ccaccagacg agagacggga caatcggccc catggacgcg
    29161 catcgactcg ccgtactcac cacccgcgca cgacaactgg cctccaccgg gccccgccgc
    29221 atcctcggtc tggccggcgc gcccggcgcg gggaagtcca ccctcgccgc ccgcctcgtc
    29281 gacgggctcg acgggctcgc cgcgctcgtg ccgatggacg gcttccacct cgcgcaggcc
    29341 gaactggaac gactcggccg tgccgcccgc aagggcgccc ccgacacctt cgacgccgcc
    29401 gggtacgcgg ccctgctcgc ccggctgcgc gctcccgagc ccggcgtcac cgtgtacgcg
    29461 ccggccttcg accgcgacct ggaggaaccc gtcgcgggca gcgtcccggt cccgcccgac
    29521 ctcccgctcg tcgtcacgga gggcaactac ctgctgcacg acgaccccgc gtgggcgccg
    29581 gtacgggcgc tgctggacga ggtgtggttc gtggagaccg acgaccgcct ccgcgtccgc
    29641 cgcctcgtcg aacgacacgt ggcccacggc aaggaccgcg cccgcgcgga gcgctgggtc
    29701 cgggagtcgg acgaggcgaa cgcgcgcctg gtcgccgcgg gccgcgaccg agcggacctc
    29761 gtcgtccacc tggcgtgatg tgacgtcgcc tcacctgacg tggtgtggac gggcgcgccc
    29821 ttccccggcc gccggcccgc gctgaccgga cccgacgcga cctgaccggc tcgaccgggc
    29881 cggcctctct ccccggcccg gccctcccgg cccggccctc ccggaccggg ggccggaccg
    29941 ggggcctgac ccgtcggccg gctgtcggcc ggccgagccc ctgttccggg ccccgggccg
    30001 agaaccgtcg gtccggtggg ccgggccgcg gggccggtga ggccgtcggg gctccgtggc
    30061 cggccgggac cgtccagact gagggcatgg accccgacct gctgcgcacg ttcgtgacgg
    30121 tgacccggct cggctccttc tcggcggccg cccacgagct cggccgcgac cggtccgcgg
    30181 tcgcccggga cctcgccgac ctcgaacgcg acctgggcct gcccctgctg acccgccggc
    30241 ccgtcgtccc caccgtggcg ggcgcccggc tcctggagca cgccgtgccg ctgctgctcc
    30301 gcctcggcgc ggcgcgcgcg gacctcgccc ggctcgccgc cgcgccggat gccgaactgg
    30361 ccgtcgccgc ctcgccgctc gccgtcggcc cccggctgct cgccgcgctc cccaccgcca
    30421 ccgcccgcgt caccctgacg gtcctgcccc gcgaggcggt acgcgccgcc ctcgccgcgg
    30481 gggccgccgt cctcggcctc gtcgaccggc tcgacgttcc gggtgacccg gccgacgacg
    30541 ggcccgaggc cgccgagccc accgccaccc gcgtcgccac ggcccccctc gccctgcacc
    30601 tgcccgccgg ggacccgctc gcccaccggt cgggtgtgcg cctcggtgac ctcgcggccg
    30661 cccgctggat cgacgccccg gccgcgggga tcccgctcga ccggctccgc gccgcccacg
    30721 gcacgtacgg gttccggccc gcgctgcgct acgacggcac cgacgtccgc accctcaccg
    30781 cgctcgccgc ggccggccgt ggactggcgc tcctgccgga gaccgtcccg gccgcccccg
    30841 gcgccaccgc cgtacccctc gtcgaaccgc ggctcgtcca ccgcgtggag ctcctgcgcg
    30901 ccgccgcccc ggcgggcccc gcggccgaac tggccgaccg cctcacccgc gcccgctgac
    30961 cgaccggccc cggcggccac cgatcaccga cgatccgccg cccccgcctc cgaccgcccc
    31021 cgcctccgac cgcccccgcc tccgaccagg acaccggcac cggccgccca gcaccaccgg
    31081 ccggccggcc gccaccacac cgccggccgg ccgccaccgc gcgtcagcgg tccgcgagca
    31141 ccacgcacga ctccgggggc accaccagcg tcccgccctc gccctccggc tccgccaccg
    31201 gctcccacgc ggccagcacc cgtacgccgt cctggcccag cgcgatcctg gccggcgcgg
    31261 agccgaggtt caccgccacc cgcacgtcac cgcggcggta cgcgatccag cgggcctcct
    31321 cgtcgtacgc gaggcggatc gccgccaggt ccgggtcggt gaggtccggc agctcggccc
    31381 gcagggcgat gagccgcgtg tgccactcca gcagccgggc gtgcggctcg cgctccggct
    31441 ccgaccagtc caggcaggag cggtcccgtg tcgccggctc ctgcgggtcg ggcacgtcct
    31501 cctccttcca gccgtgcgcc gcgaactccc gccgccgccc ggtgcggacc gcctccgcca
    31561 gctccgggtc ggtgtggtcg gtgaagaact gccacggtgt ccccgcgccc cactcctcgc
    31621 ccatgaacag catcggcgtg aacggcccgg tgaggacgag cgccgccgcg cacgccagca
    31681 ggccggggga gagggacgcc gagagcc
//
