LOCUS       NZ_CP102332            21089 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Streptomyces changanensis strain HL-66 chromosome, complete genome.
ACCESSION   NZ_CP102332
VERSION     NZ_CP102332.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces changanensis
  ORGANISM  Streptomyces changanensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6817869)
  AUTHORS   Wu,H. and Han,L.
  TITLE     Streptomyces changanensis sp. nov., an actinomycete isolated from
            soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6817869)
  AUTHORS   Wu,H. and Han,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2022) College of Forestry (Academy of Forestry),
            Northwest A&F University, Northwest A&F University, Yangling,
            Shaanxi 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.9; Pilon v. 1.24
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 187.45x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024600715.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 19:18:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,071
            CDSs (total)                      :: 5,982
            Genes (coding)                    :: 5,812
            CDSs (with protein)               :: 5,812
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 170
            CDSs (without protein)            :: 170
            Pseudo Genes (ambiguous residues) :: 0 of 170
            Pseudo Genes (frameshifted)       :: 70 of 170
            Pseudo Genes (incomplete)         :: 131 of 170
            Pseudo Genes (internal stop)      :: 9 of 170
            Pseudo Genes (multiple problems)  :: 37 of 170
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:13:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5342791
            Orig. end                         :: 5363880
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102332.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21089
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="15"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21089
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21089
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11089](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11089)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(890..1090)
                     /locus_tag="NRO40_RS23400"
                     /old_locus_tag="NRO40_23400"
     CDS             complement(890..1090)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192932.1"
                     /locus_tag="NRO40_RS23400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23400"
                     /product="cold-shock protein"
                     /protein_id="WP_058941408.1"
                     /transl_table=11
                     /translation="MASGTVKWFNSEKGFGFIEQEGGPDVFAHYSEIQGNGYRELTEGE
                     RVTFDVGQGPKGPQAQNIVRG"
     gene            complement(1362..2891)
                     /locus_tag="NRO40_RS23405"
                     /old_locus_tag="NRO40_23405"
     CDS             complement(1362..2891)
                     /EC_number="2.5.1.7"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010033920.1"
                     /locus_tag="NRO40_RS23405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23405"
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="WP_058941407.1"
                     /transl_table=11
                     /translation="MADDYLVRIGKLIRDARQHRGWTQTQLAEALATSQSAVNRIERGN
                     QNISLEMIARIGEALDSEIVSLGYAGPMHLRVVGGRRLSGAIDVKTSKNACVALLCASL
                     LNKGRTVLRRVARIEEVYRLLEVLSSIGVRARWINDGRDLEIAPPAELNMEAIDADAAR
                     RTRSIIMFLGPLLHRVHSFKLPYAGGCDLGTRTIEPHMIALRRFGLDITATEGLYHAQV
                     DPSVSPDRPIVLTERGDTVTENALLAAARHDGTTVIRNASSNYMVQDLCFFLEALGVRV
                     DGIGTTTLTVHGVPHIDVDVDYSPSEDPVEAMSLLAAAVVTESELTIRRVPIEFLEIEL
                     AVLEEMGLDHDRSTEYTADNGRTRLVDLTVRPSKLEAPIDKIHPMPFPGLNIDNVPFFA
                     AIAASAQGQTLIHDWVYDNRAIYLTDLNRLGGRLQLLDPHRVLVEGPTRWRAAEMMCPP
                     ALRPAVVVLLAMMAAEGTSVLRNVYVINRGYEDLAERLNSVGAQIEIFRDI"
     gene            3296..5728
                     /locus_tag="NRO40_RS23410"
                     /old_locus_tag="NRO40_23410"
     CDS             3296..5728
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015155.5"
                     /locus_tag="NRO40_RS23410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23410"
                     /product="MMPL family transporter"
                     /protein_id="WP_079046932.1"
                     /transl_table=11
                     /translation="MLTRLARLAINRPKWVLVGALLVVVFCGVFGASVTDRLKAGGYTS
                     PDSESARAAKLVNEHFDGAQPNLIVAVTTGAGADAGAGAAAGAGVDSAAARRAGARITE
                     WMGARDDIEGVQSYWTLGPQAGAALRSEDGASGLVMARIDASDTDLPKIAERVKADLPR
                     PEGVTVRVGGYGPLTAEMESQVTRDATIGEAVAFPISLIVLVVVFGSLVAAGLPLLIGA
                     VSIVTTLAILRLVTTFADVSIYALNMTTVLGLALGIDYSLFMVSRFREELRNGLDVPAA
                     VLRTVQTAGRTVMFSAVTVALALAALIVFPMFFLKSFAYVGVAVVLAAALAAVLVLPAA
                     LTLLGHRVDRYDVRVPLRRWFGMKPPRWVAPEESRWYRMVVAVTRRAVPVAVLTTVGLL
                     VLGAPFLSSKWGYPDDRVIAASAAESRQVGDLLREEFAQDAAASMTVVLPGFDGGAREL
                     APYATALSRVDGVSTVVSGGGTFADGAQVGPAAAGMVNDAGAVVRVGTAVDPYSDDGER
                     LLTALRDVRGPGEALFAGAAAENQDVLDALTGPLPYAAALIALTMFVLLFLFTGSVVLP
                     VKALLMNTLSLAAAFGAMVWVFQEGHLSGLLGFTPTGYLVANIPVLMFCLAFGLSMDYE
                     VFLLSRIREEWLASGRTTTEDNTHAVAMGVARTGRVFTAAALLMAIVLIGMGVSKVSFM
                     QLFGLGLALTVLVDAVVVRCLLAPAMMRLMGRFNWWAPPALSRLHARIGLTEEAHPAPP
                     ADRHEPAAAGGASAGAPAPTGDPTTGAARTDGTVRTDGTARTDGTARTDGTVRTDGR"
     misc_feature    complement(3310..3326)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 18.82"
                     /tool="antismash"
     gene            5980..6342
                     /locus_tag="NRO40_RS23415"
                     /old_locus_tag="NRO40_23415"
     CDS             5980..6342
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015735.5"
                     /locus_tag="NRO40_RS23415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23415"
                     /product="YciI family protein"
                     /protein_id="WP_079046931.1"
                     /transl_table=11
                     /translation="MAEYLLLIYEDEARTSALEPADDAALVDEFQRFMARNATRVREGR
                     RLAPTSAAVSARRDVDGGVRISDGAFVESKEVVAGYFLVEAADLDEALAVAGQVPVPHG
                     GVEVRPIRSVRPTPDA"
     gene            6359..7600
                     /locus_tag="NRO40_RS23420"
                     /old_locus_tag="NRO40_23420"
     CDS             6359..7600
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105905.1"
                     /locus_tag="NRO40_RS23420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23420"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_058941405.1"
                     /transl_table=11
                     /translation="MDATVASVVADAHRRQWGFVLAATVRVTRDLDLAEECVQEAYAQA
                     LTQWAGGGVPDRPEAWLTTVARRRAVDVVRRRDTLRDKLPLLAEDDTAPPADQDIAGRD
                     IPDDRLRLIFTCCHPSLDVDTRVGLTLRLVCGLSTAETARALLVSEPAMAARITRGKKK
                     IKAARIPYREPPPEELPARVDAVLDVVHLVFSTGYTAPSGDRLQRRDLVERAEHLARVL
                     HQLLPGRSGPAGLLALILLTDARRHTRTRPDGSLAPLSEQDRTRWDAAQIQEGLRLAGT
                     ALRHRPPTRYALMAAVAAVHARAPGWEATDWPRIVDLYDTMLRVWPSPVVALNRAIAVG
                     QARGPAAGLAALDELVAERQLAGYQYLAAARADFLRRLGRAGEARTAYREALRVTENAV
                     EREFLESRLEELGD"
     gene            7790..9376
                     /locus_tag="NRO40_RS23425"
                     /old_locus_tag="NRO40_23425"
     CDS             7790..9376
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS23425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NRO40_23425"
                     /product="hypothetical protein"
                     /protein_id="WP_058941404.1"
                     /transl_table=11
                     /translation="MPLRSVDGGPTAAPAPPPAGRPPAGEPPAGRLTAGGRRTGEPTAG
                     PAGRAAGSAAAPRRPAREPRPAEPRPAEPRPTEPRLTPPPTAVSPTREASAAVATDEPA
                     EPAEPAAPPAGRAVTLAERRALTHAYATRYARAGKREKSRILDRVCAATGWHRSHARRA
                     LLDASRPRPARPARGGRTPYDADVVAALTFCWTILDMPAGKRLAPVLPELVPVLRRHGE
                     LAVDDETAALLTGMSAATIDRRLAPLRRRSDPVPVARIRPGSLLRDEPPLLTFAEWDHS
                     RPGFLEVAVVHHDAGGGRDGHGEPERDAHGERGGHLLTVSATDIATGWSENRTVRAVNW
                     LPYALDEIAGTLPFPVLGIESGAHGDARTGEMLLRWCEQRGVTLTRARPSRAGNHHVGQ
                     KNWSTLHAVTAGHRYDTRAQALLLNRIWATLSQLTNHFSPQQHSVRVTGPDGRRRKEYD
                     TATPLRRTARHPAVSAEDKAILADTHARLNPAALHRRVRVLTGRLHLTVAGGAAAAHSA
                     ERPGRAPGAAS"
     gene            complement(10001..11089)
                     /locus_tag="NRO40_RS23430"
                     /old_locus_tag="NRO40_23430"
     CDS             complement(10001..11089)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011208270.1"
                     /locus_tag="NRO40_RS23430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23430"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_058941403.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.2e-47, bitscore:
                     159.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVDHPEVTAGTAAVDAALRTFLAERRAGAAAIGEGYATAVADLE
                     EYVLRGGKRVRPTFAWTGWLGAGGDPDGPTAPAVLRTCAALELLHASALIHDDIVDASR
                     TRRGFPSAHVAFADRHRERGWSGDPDAYGTGAALLVGDLALVWADDLVRTSGLPADAMT
                     RVGPVWSAMRTEVLCGQLLDLAAEARGDESADAALLKDRYKTASYTVERPLHVGAAAAG
                     ADQGLVAAYRAFGADIGLAFQLRDDVLGVFGDPEVTGKPSGDDIREGKRTVLLATALRR
                     ADDRDPAAARFLRSRIGTDVSEDDLDSVRAILVGLGAVAYVEREITRRRDRAVAVLERS
                     AATRPARERLAAMALSATQRSR"
     gene            complement(11097..12035)
                     /locus_tag="NRO40_RS23435"
                     /old_locus_tag="NRO40_23435"
     CDS             complement(11097..12035)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS23435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NRO40_23435"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_058941402.1"
                     /transl_table=11
                     /translation="MPGERAPLAARLKYALVIRRYEFLPVYVPLVLTPALLGARSWGEF
                     ASLDAVLALVYVISGLQVANMTNALADREQDRQLKSRQSDAVYGLGVPRVVAHIAVSTA
                     VCAALALYLTVRAQQWGMLLPALAAGLIGFQYSLPPLHLKSAGLWQLLALQNGCVFLPG
                     LFVLWSFGHPLEWGSVVAVLGFALALTSLFVTSHGEDYLVDGRFGIRTYVRALGLVRAF
                     RVQLAMLVAGGVLILVSVPATFGFSWGLLPFLAAWLVSIRFLDAVVRDVRRAPLHEAVA
                     DLHGKSLLGPYHSSLLSWATVVLAASVLIGR"
     gene            complement(12169..12498)
                     /locus_tag="NRO40_RS23440"
                     /old_locus_tag="NRO40_23440"
     CDS             complement(12169..12498)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015925.5"
                     /locus_tag="NRO40_RS23440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23440"
                     /product="putative quinol monooxygenase"
                     /protein_id="WP_058941401.1"
                     /transl_table=11
                     /translation="MTETVIRTEDNLLTLINVFEVEASKQDELVALLNEGVEKVFRHRP
                     GFVSATVLVGKDGTKVVNLAQWRSQEDIQATLADPAAQEYGRKTAALGKPAPGVYSVAS
                     VFGAA"
     misc_feature    complement(12830..12844)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    12868..12886
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.41"
                     /tool="antismash"
     misc_feature    complement(12883..12901)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.29"
                     /tool="antismash"
     gene            12968..15808
                     /locus_tag="NRO40_RS23445"
                     /old_locus_tag="NRO40_23445"
     CDS             12968..15808
                     /EC_number="4.2.1.3"
                     /GO_function="GO:0003994 - aconitate hydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010474602.1"
                     /locus_tag="NRO40_RS23445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23445"
                     /product="aconitate hydratase"
                     /protein_id="WP_058941400.1"
                     /transl_table=11
                     /translation="MSANSFDARSTLRVGDESYEIFRLDKVEGSARLPYSLKVLLENLL
                     RTEDGANITADHIRALGGWDSQAQPSQEIQFTPARVIMQDFTGVPCVVDLATMREAVKE
                     LGGDPSKINPLAPAELVIDHSVIADKFGTAEAFGQNVELEYGRNKERYQFLRWGQTAFD
                     EFKVVPPGTGIVHQVNIEHLARTVMVRGGQAYPDTLVGTDSHTTMVNGLGVLGWGVGGI
                     EAEAAMLGQPVSMLIPRVVGFKLTGELPTGTTATDLVLTITEMLRKHGVVGKFVEFYGE
                     GVAATSLANRATIGNMSPEFGSTAAIFPIDDETLKYLKLTGRSEQQVALVEAYAKEQGL
                     WLDPAAEPDFSEKLELDLSTVVPSIAGPKRPQDRIVLAEAAEQFKRDVLNYVEAGVTGG
                     DDRKPGVPQQEQPHGVASPVDEASAESFPASDAPAYGHDDNGAGAPQHDEATGEAVPSR
                     PVTVTAADGSTYEIDHGAVTVAAITSCTNTSNPYVMVAAALVAKKAVEKGLTRKPWVKT
                     TLAPGSKVVTDYFDKAGLTPYLDKVGFNLVGYGCTTCIGNSGPLPEEVSKAVNDHDLAV
                     TSVLSGNRNFEGRINPDVKMNYLASPPLVVAYALAGSMKVDITKDALGTDQDGNPVFLK
                     DIWPSEAEVNDVVANAIGEDMFNKSYQDVFAGDAQWQALSIPTGDTFEWDPQSTYVRKP
                     PYFEGMTMETTPVADITGARVLAKLGDSVTTDHISPAGAIKADTPAGQYLTEHGVERRD
                     FNSYGSRRGNHEVMIRGTFANIRLRNQIAPGTEGGYTRDFTRADEGAPVSFIYDASRNY
                     IEQGIPLVVLAGKEYGSGSSRDWAAKGTALLGVKAVIAESYERIHRSNLIGMGVLPLQF
                     PEGASAESLGLTGEETFSIAGVTELNEGTTPRTVKVTTDTGVEFDAVVRIDTPGEADYY
                     RNGGIMQYVLRNLIRG"
     gene            complement(15908..16522)
                     /locus_tag="NRO40_RS23450"
                     /old_locus_tag="NRO40_23450"
     CDS             complement(15908..16522)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017239479.1"
                     /locus_tag="NRO40_RS23450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23450"
                     /product="DUF4291 domain-containing protein"
                     /protein_id="WP_058941399.1"
                     /transl_table=11
                     /translation="MEEPHQRVRALRTDTTVTVYQAYSPAIGLPAAREGRFPASWKRDR
                     MTWIKPSFLWMMYRCGWAAKEAQETVLAVEIRRAGFEWALRHACLSHYRAGLHASPEAW
                     RRELRDAPARVQWDPERDLHLRPLPYRSLQLGLAGEAARRYADEWTVSITDVTPLAHEV
                     HALVRAGDLDGARRLLPREEPYPTPDGLLDRLVGTGPAVAA"
     gene            complement(16696..20544)
                     /locus_tag="NRO40_RS23455"
                     /old_locus_tag="NRO40_23455"
     CDS             complement(16696..20544)
                     /EC_number="3.2.1.-"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005310549.1"
                     /locus_tag="NRO40_RS23455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_23455"
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="WP_257375496.1"
                     /transl_table=11
                     /translation="MRLRPLRTAVVLAAVSLLVAGSPPAVQASPARPAAPAQEFTTSFE
                     PDEAPPTWRDTVETGPDGRERARGVDGAFAAGIPGDVTDRVTGVRASGEHAEAGETKEN
                     LLDSEPTTKWLTLAPTAWLEFTLEEPLPVVSYALTSANDHAARDPRAWTLHGSADGTRW
                     TPLDTRENETFPERFRTRTYHFANTTRYAHYRLEITANNGAPATLQLADVHLSDGDGTA
                     PAPRTMRSHVDRGPAGSPTAKAHAGFTGLRALRYAGTHRAAGPGHSYNKVFDVHVAVGP
                     TTELSYRIHPSLPAGPGGTGADLTYPATHVAVDLAFTDGTYLSGLRATDSHGGVLTPRG
                     QAAAKRLYANQWNQVTAGIGAVAAGRVVDRILVAYDAPRGPARFQGWLDDVTLSRAAPE
                     PAHVHPSAYVSTVRGTHSSGAFSRGNTFPATAVPHGFNFWTPVTNAASKSWLYEYARGN
                     TANNLPALQAFSASHEPSPWMGDRQTFQVMPSAAPGPGAPPTERAARALEFRHGNESAR
                     PHHYRVRFENGLTAEIAPADHAATMRFTFPGDDASVVFDNITQEGGLTLDPATSSFTGY
                     SDVKSGLSTGATRMFVHGVFDAPVTASSAEGVRGFLRFAAGRDRTVHLRMATSLISVEQ
                     ARRNLAAEIPAGTPFAAVAAAARAQWDRLLGRVRVEGATRDQLTTLYSGLYRLYLYPNS
                     GHERVDGRWRYASPFSPQTGPDTPTHTGAKIVDGKVYVNNGFWDTYRTTWPAYSFLTPR
                     RAGELVDGFVQQYRDGGWISRWSSPGYADLMTGTSSDVAFADAYVKGVRFDAEAAYEAA
                     LKNATVLPPGRGVGRKGMATSPFTGYASTETHEGLSWSMEGYVNDFGLARMARELHRRT
                     GEARYGEEAAYFLDRARGYVALFDAEAGFFQGRDARGRWRVPSASYDPRVWGYDYTETN
                     GWGYAFTAPQDSRGLANLYGGRAGLAAKLDAYFSTPETGAPEFAGSYGGVIHEMTEARD
                     VRMGMYGHSNQVAHHVAYMYDAAGQPWKTQEKVREVLSRLYVGSEIGQGYHGDEDNGEQ
                     SAWYLFSALGFYPLVMGAGEYAVGSPLFTKATVRTDDGAVLVVKAPRNSPRNVYVQGLR
                     VNGRQWTSTALPHGLLARGGTLEFDMGPRPSTWGTGADAAPASVTRDDRVPVPRRDALS
                     GPGPLFDDTSATAGPVSGAVELPVPGPVRAVQYTLTSAAAAAAPDGWVLEGSTDGARWR
                     EVDRRSGEVFRWDRQTRVFTVARPGAYRAYRLVAADAGAGAGRELAEVELLARPPRG"
     misc_feature    complement(20194..20196)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(20536..20538)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(20570..20581)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.52"
                     /tool="antismash"
     misc_feature    20723..20737
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.32"
                     /tool="antismash"
     misc_feature    complement(20748..20766)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.39"
                     /tool="antismash"
     misc_feature    complement(20783..20798)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.36"
                     /tool="antismash"
     misc_feature    complement(20962..20976)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.29"
                     /tool="antismash"
ORIGIN
        1 tcaacgacct gctccggccc cggttcgacg ccgcggaggc ggccgggcac ctggaggaga
       61 tgttcgccgc gctgacggct gccgggaccc acgtggtgac actgaccttc cccgacttcg
      121 ggaagatcgc gccccttgcc cggcccatca ggtcccgcgt gttcgacctc aacacccgca
      181 tccgtgccgc ggccgcccgt cacggggtca cggtcgccga aacggaccgg cacgccgtca
      241 ccaccgaccc acgactgtgg accgcggacc gactccacgc cagctccctc ggccacgaac
      301 ggatcgccgc ggccctcgcc caggccctcc gcctgcccgg aagcgacgac gcctggacac
      361 gccccctccc gccgcagagg gtcgccacgg gctggcacgc cgcaggagcc gaactgcgct
      421 gggcggccac tttcctcggt ccctggctcg gacgccgtct gcgcggccgg tcctccggcg
      481 acggccgtac cgcgaaacgc ccgcggctcc tgcccgtgag cgccaccgcc gactcctcgg
      541 cgggcaccgg gcgacgggaa ggtccgtagc gacggcatcg gcccccaggc gcggcccccg
      601 gacccgggga tccgtggtga cgccgcgcgt caccacgcgc tgtacggggc cgcgtcccct
      661 ggttccggtc ggccggaccc cggcgatcgt gccgagggcg gggcccgcgt cgccgcgggc
      721 gcggacggca gccgcgcggg tggccgggcg ggtggccggg cggtgtccat gccgggaggc
      781 gagggcctcc ccgcccgacg ggtgtcacgc cgaatcgacg ggtgccacgc cggaagggcc
      841 gcgacaggtg tcgcggccct tcgtcacccc gagatcggtc cggaggagtt cagcctcgga
      901 cgatgttctg cgcctgcggc cccttcggtc cctggccgac atcgaacgtg acgcgctcgc
      961 cctcggtcag ctcgcgatac ccgttgccct ggatttcgga gtagtgggcg aagacgtccg
     1021 ggccgccttc ctgctcgatg aacccgaagc ccttctcgga gttgaaccac ttcacggtgc
     1081 cgctggccat actgcattcg tccttcgctc atgcacggag cagcccatgg tcggacgtgc
     1141 cccggcccct gctgaatcag gagccacagt ggttctaccc cgcttcggcc ggatcatcct
     1201 acggacgaca cgccgttgcc ccgccacggt ccgccgggca gcggttccgc cactcctccg
     1261 ccggtgaggg gcccggcggt cacggcgagg cctcccgtcg gccgaaccgc cgcccgaccc
     1321 gcttcatccg aggtcaggcg gggtgcggcg gcattcgcgt atcagatgtc gcggaagatc
     1381 tcgatctggg cgccgaccga gttgaggcgc tcggcgaggt cctcgtagcc gcggttgatg
     1441 acgtagacgt tgcgcaggac ggaggtgccc tcggcggcca tcatggccag gaggaccacc
     1501 acggcggggc gcagggcggg cgggcacatc atctcggcgg cgcgccagcg cgtggggccc
     1561 tccaccagga cgcggtgcgg gtccaggagc tggaggcggc cgccgagccg gttgaggtcc
     1621 gtcaggtaga tggcgcggtt gtcgtagacc cagtcgtgga tgagggtctg accctgtgcg
     1681 gaggcggcga tggccgcgaa gaacgggacg ttgtcgatgt tcagtcccgg gaacggcatg
     1741 gggtggatct tgtcgatggg cgcctccagc ttggaggggc gcaccgtcag gtccacgagc
     1801 cgggtgcggc cgttgtccgc ggtgtactcg gtggagcggt cgtggtcgag gcccatctcc
     1861 tccaggaccg cgagctcgat ctccaggaac tcgatgggga cccggcggat cgtcagctcc
     1921 gactccgtca ccacggcggc ggcgagcagg ctcatcgcct cgaccgggtc ctcggagggg
     1981 gagtagtcga cgtccacgtc gatgtggggg acgccgtgga cggtgagggt cgtggtgccg
     2041 atgccgtcga cgcgtacgcc cagggcctcc aggaagaagc agaggtcctg gaccatgtag
     2101 ttggaggacg cgttgcggat gacggtggtg ccgtcgtggc gcgcggcggc cagcagcgcg
     2161 ttctcggtga cggtgtcgcc gcgttcggtc aggacgatgg gacggtcggg ggagaccgac
     2221 gggtcgacct gggcgtggta caggccctcg gtggccgtga tgtcgagacc gaaccggcgc
     2281 agggcgatca tgtgcggctc gatggtgcgg gtgccgaggt cgcagccgcc ggcgtagggc
     2341 agcttgaagg agtgcacgcg gtgcaggagc ggcccgagga acatgatgat cgagcgggtg
     2401 cggcgggccg cgtccgcgtc gatcgcctcc atgttcagct cggcgggcgg cgcgatctcc
     2461 aggtcgcggc cgtcgttgat ccagcgggcg cggacgccga tggagctgag gacctccagc
     2521 agccggtaga cctcctcgat ccgtgcgacg cggcgcagga cggtgcggcc cttgttcagc
     2581 agggaggcgc acagcagggc cacgcaggcg ttcttgctcg tcttgacgtc gatggcgccg
     2641 gagaggcggc ggccaccgac cacccggagg tgcatgggtc cggcgtagcc cagcgagacg
     2701 atctcgctgt cgagtgcctc gccgatacgg gcgatcatct caaggctgat gttctggttt
     2761 ccgcgctcga tgcggttgac ggcgctctgg ctggtggcca gcgcctcggc gagctgcgtc
     2821 tgtgtccagc cgcggtgctg gcgggcgtca cggatgagct tgccgatgcg tacgaggtag
     2881 tcgtctgcca tagaggcagg ctatctcaga tatgagatgg ccttctcgtt gggctgcgcc
     2941 atccgcgtca gcgggacgta tcagcgcatg tcaggacctg tgcaccgggc gccggttggc
     3001 tgtcggcggc ggatgaggcc gcgtcacccc tccctgggta ccccgcttcg ccggcttctc
     3061 tcggaaaacc cccgaagttg cccgaatcgg acggatggcc ttcggggtgg tgccgagggg
     3121 tgccgccgag ggagtggcgc ggaggggccg gtgagaggcg ggcgggcgcg tcacgcgttc
     3181 acaagcgcat cgcgtgcggc aacgcacccg tggttcacgg acggcaagcg acctaagtta
     3241 tgccggaaca tcaccacaag caacatgcca ggggaaaccc ggtagggata cagcgatgtt
     3301 gacccgactt gcccgtctcg ccatcaatcg gccgaaatgg gtcctcgtcg gcgcgctact
     3361 ggtcgtggtc ttctgcggcg tcttcggtgc gtcggtgacg gatcggctga aggccggcgg
     3421 gtacacctcg ccggactccg agtcggcccg tgccgcgaag ctcgtcaacg agcacttcga
     3481 cggcgcccag cccaacctca tcgtcgccgt gaccaccggc gccggggccg acgcgggtgc
     3541 cggggcggcc gcgggcgcgg gcgtcgacag cgccgcggcg cgccgcgcgg gcgcgcggat
     3601 cacggagtgg atgggcgcgc gcgacgacat cgagggcgtg cagtcctact ggaccctcgg
     3661 gccgcaggcc ggtgccgcgc tgcgcagcga ggacggcgcc agcggtctcg tcatggcgcg
     3721 catcgacgcc agcgacaccg acctgccgaa gatcgcggag cgggtgaagg cggacctccc
     3781 gcggccggag ggggtcaccg tgcgggtcgg cggctacggc ccgctcaccg ccgagatgga
     3841 gagtcaggtc acccgggacg ccaccatcgg cgaagccgtg gccttcccca tctccctcat
     3901 cgtgctcgtc gtcgtcttcg gcagcctcgt cgcggccggc ctgccgctgc tcatcggcgc
     3961 ggtctccatc gtgacgacgc tcgccatcct gcgcctggtc accaccttcg cggacgtgtc
     4021 catctacgcc ctcaacatga ccaccgtgct cgggctcgcc ctcggcatcg actacagcct
     4081 cttcatggtg agccggttcc gcgaggagct gcgcaacggc ctcgacgtcc ccgccgcggt
     4141 cctgcgcacc gtccagacgg ccggccgtac cgtcatgttc tccgcggtga cggtggcgct
     4201 cgccctcgcc gcgctcatcg tcttcccgat gttcttcctc aagtcgttcg cgtacgtcgg
     4261 cgtcgccgtc gtgctcgccg cggccctcgc cgccgtcctg gtgctgcccg cggccctcac
     4321 cctgctcggc caccgcgtcg acaggtacga cgtccgcgtc ccgctgcgtc gctggttcgg
     4381 gatgaaaccg ccgcggtggg tcgcgccgga ggagagccgc tggtaccgga tggtcgtggc
     4441 cgtcacgcgc cgcgccgtgc ccgtcgccgt cctcaccacc gtcggtctgc tggtgctcgg
     4501 cgcgcccttc ctgtcgtcca agtgggggta ccccgacgac cgggtgatcg ccgcgtccgc
     4561 cgccgagagc cgccaggtcg gcgacctgct gcgggaggag ttcgcccagg acgccgccgc
     4621 ctcgatgacc gtcgtgctgc ccggcttcga cggcggggcc cgcgaactcg ccccgtacgc
     4681 cacggcgctc tcccgtgtcg acggcgtgtc gaccgtcgtg agcggcggcg gcaccttcgc
     4741 cgacggggcg caggtcggcc ccgccgcggc cgggatggtg aacgacgcgg gcgccgtcgt
     4801 ccgcgtcggc accgccgtcg acccgtactc cgacgacggc gagcggctgc tgaccgccct
     4861 gcgcgacgta cggggaccgg gcgaggcgct cttcgccggc gccgcggccg agaaccagga
     4921 cgtgctggac gccctcaccg ggccgctgcc gtacgcggcc gcgctcatcg cgctcaccat
     4981 gttcgtgctg ctgttcctct tcaccggcag cgtggtgctg cccgtgaagg cgctgctgat
     5041 gaacacgctg tcgctcgccg ccgcgttcgg cgcgatggtc tgggtcttcc aggagggcca
     5101 cctctccggc cttctcggct tcacgccgac cggctacctc gtcgccaaca tcccggtcct
     5161 gatgttctgt ctggcgttcg gcctgtcgat ggactacgag gtgttcctgc tctcccgcat
     5221 ccgcgaggag tggctcgcct ccggccgcac caccaccgag gacaacacgc acgccgtcgc
     5281 gatgggcgtc gccaggaccg gtcgcgtctt caccgccgcc gcgctcctca tggccatcgt
     5341 cctgatcggc atgggcgtgt cgaaggtgtc gttcatgcag ctcttcgggc tggggctcgc
     5401 cctgacggtc ctggtggacg ccgtcgtcgt ccgctgcctg ctcgccccgg ccatgatgcg
     5461 gctgatgggc cgtttcaact ggtgggcgcc gcccgcgctg agccggctgc acgcccgtat
     5521 cggcctcacg gaggaggcgc acccggcccc gccggccgac cggcacgagc ccgccgcggc
     5581 cggcggcgcg tccgccggag ccccggcgcc caccggcgac ccgaccaccg gagccgcccg
     5641 taccgacggg accgtacgga ccgacgggac cgcccgtacc gacgggaccg cccgtaccga
     5701 cgggaccgta cggaccgacg gccgctgagc cacccggtcg gccccgccgc cccgcctccg
     5761 cacggcatga cgtggccgtc gtcgcggggg ccggggcccg tgggcggccg cgctcccacg
     5821 acacgcccac cggtgaagat cctgtgatct cccgtcccgc ccccgccgcc gggtgggaga
     5881 aaggggcggc gtcgtcgcgc ttttcgccgg cgaccctccg cacgcccggt gttgtaccgt
     5941 gagcgggcgg ttgccggggg cagcgaaggg cacggagcgg tggcagagta cttgctgttg
     6001 atctacgagg acgaggcgcg gacgagtgcc ctggagccgg cggacgacgc cgcgctcgtc
     6061 gacgagttcc agcggttcat ggcgcgcaac gccacccggg tgcgcgaggg caggcgactg
     6121 gcgccgacct ccgcggccgt gtccgcccgg cgggacgtcg acggcggcgt gcggatcagc
     6181 gacggcgcgt tcgtcgagtc caaggaggtc gtcgccgggt acttcctcgt cgaggccgcc
     6241 gacctggacg aggcgctcgc cgtcgccgga caggtccccg taccgcacgg aggcgtcgag
     6301 gttcgcccga tccgctccgt ccggccgaca ccggacgcct gacatcgacg accccccgat
     6361 ggacgcgacc gtcgcgtcgg tggtcgccga cgcccaccgc cggcagtggg gcttcgtgct
     6421 cgcggcgacc gtacgggtca cccgcgacct cgacctggcc gaggagtgcg tgcaggaggc
     6481 gtacgcccag gcgctcacgc agtgggccgg cggcggcgta ccggaccggc ccgaggcgtg
     6541 gctcaccacc gtcgcccggc gccgcgccgt ggatgtcgtc cgccgccgcg acaccctgcg
     6601 cgacaagctg ccgctgctcg ccgaggacga caccgcgccc cccgccgacc aggacatcgc
     6661 gggccgggac atcccagacg accggctgcg gctgatcttc acctgctgcc acccgtcgct
     6721 cgacgtcgac acccgtgtgg gcctcaccct gcggctggtg tgcggtctgt ccaccgcgga
     6781 gaccgcccgc gcgctgctcg tctccgaacc ggcgatggcc gcccgcatca cccgcggcaa
     6841 gaagaagatc aaggcggccc gcatccccta ccgggagccc ccgcccgagg agctgcccgc
     6901 gcgcgtggac gccgtcctcg acgtcgtcca cctcgtcttc agcaccggct acaccgcccc
     6961 gtccggcgac cggctccaac gccgcgacct ggtcgaacgc gccgagcacc tcgcccgcgt
     7021 cctgcaccag ctgctgcccg gcaggtccgg gccggccggg ctgctggcgc tcatcctgct
     7081 gaccgacgcc cggcggcaca cccgcacgcg ccccgacggc tccctcgcgc cgctctccga
     7141 acaggaccgc acgcgctggg acgccgcgca gatccaggag gggctacggc tggccgggac
     7201 cgccctgcgg caccggccgc ccacgcggta cgcgctcatg gccgccgtcg ccgccgtcca
     7261 cgcgcgcgcc cccggctggg aggccaccga ctggccccgc atcgtcgacc tgtacgacac
     7321 gatgctgcgg gtgtggccgt cgcccgtcgt ggcgctcaac cgggccatcg ccgtcggcca
     7381 ggcgcggggg cccgccgccg gcctggccgc gctcgacgag ctggtcgccg aacgacagct
     7441 ggccggctac cagtacctcg ccgccgcccg cgccgacttc ctgcggcggc tggggcgggc
     7501 cggcgaggcg cggacggcct accgcgaggc gctgcgcgtc accgagaacg ccgtcgagcg
     7561 cgagttcctg gagtcgcgcc tggaagaact cggcgactga tcgcaccgga ttgtcgatcc
     7621 gggcgtccgc tcgtccgacg tacgggtgag gagcctcaga gggaggcccc agccgtatgg
     7681 gggagcgttg accagctcgg ccgaagccgt ggtccccgtc aggaccgagg cccgtacgca
     7741 cacacgcccg gcagcagcac caccgccccg ggaacgggtc ccggcgcgcg tgccgctgcg
     7801 ttccgtcgac ggcggcccca ccgccgcgcc ggccccaccg cccgccggcc ggccgcccgc
     7861 cggggagccg cccgccggga ggctgaccgc cggtgggcgg cgcaccgggg agccgaccgc
     7921 cggaccggcg ggccgggctg ccggatcggc tgccgcgccc cggcggcccg cgcgggagcc
     7981 ccgccccgcg gagccccgcc ccgcggagcc tcgccccacg gagccccgtc tcaccccgcc
     8041 acccaccgcg gtatccccga cgcgcgaggc ctccgcggct gtcgcgacgg acgagcccgc
     8101 cgagcccgcc gagcccgccg cgccacccgc cgggcgggcc gtcacgctcg ccgagcgccg
     8161 ggcactcacc cacgcgtacg ccacccggta cgcccgcgcc ggcaagcggg agaagtcacg
     8221 gatcctcgac cgggtgtgcg ccgccacggg atggcaccgc agccacgccc gccgcgcgct
     8281 gctggacgcc tcccgacccc ggccggccag gcccgcgcgg ggagggcgga ccccctatga
     8341 cgcggacgtc gtcgccgcgc tcaccttctg ctggacgatc ctcgacatgc ccgcgggcaa
     8401 gcggctcgcg ccggtactgc ccgagctggt gcccgtactg cgccgccacg gtgagctggc
     8461 cgtcgacgac gagaccgcgg cgctcctgac ggggatgtcc gccgcgacga tcgaccgccg
     8521 tctggcgccg ctgcgccgcc ggtccgaccc ggtcccggtc gcacgcatcc ggcccggttc
     8581 gctgctgcgg gacgaaccgc ccctgctcac cttcgcggag tgggaccact ccaggcccgg
     8641 cttcctggag gtcgcggtcg tccaccacga cgccggcggc gggcgtgacg ggcacgggga
     8701 gccggagcgg gacgcacacg gggagcgggg cggccacctc ctgaccgtgt ccgcgaccga
     8761 catcgccacc ggctggtccg agaaccgcac cgtccgcgcc gtcaactggc tgccgtacgc
     8821 gctggacgag atcgccggta cgctcccctt ccccgtcctc ggcatcgagt caggcgccca
     8881 cggtgacgcc cggaccgggg agatgctgct gagatggtgc gagcagcgcg gggtcaccct
     8941 cacccgcgcc cgcccctccc gggccggtaa ccaccacgtc gggcagaaga actggagcac
     9001 gctgcacgcc gtcaccgccg gccaccgcta cgacacccgc gcgcaggccc tgctgctcaa
     9061 ccggatctgg gcgacgctgt cacagctgac gaaccacttc tccccgcagc agcactcggt
     9121 acgggtgacc ggcccggacg ggcggcggcg caaggagtac gacacggcca cgccgctgcg
     9181 gcgtaccgcg cgccaccccg cggtgagcgc ggaggacaag gcgatcctcg ccgacaccca
     9241 cgcccgcctc aacccggcag cgctgcaccg acgggtccgg gtgctgacgg gccgcctcca
     9301 cctgacggtg gcgggcggcg cggcagcggc ccactcagcg gagcgccccg gcagggcgcc
     9361 cggcgccgcc tcctgacgac gacgacgtac gacacgaccc cgcgcccggc gccgccgcgc
     9421 cccggcaccc caccccaccc cccccgcacc ccaggccccg cgacgggccg gccgccgcgc
     9481 aggccgcccg accgcggggc cccgggacac accggcgcgc cggggcggac agggccacac
     9541 gggggcgatg gaggggcgcc gagacgccgg ggcaccggga aaggagcacc agaccaccga
     9601 cggttcgatc accggccccg ggaccacccg gccaccggcc cctgggatca cccgacggga
     9661 ccccgacccc tggccaccgg cccccagacc acccgacccc ggggccaccc gacaaccggg
     9721 accatccggc cccggggcta cccgacaacc gggaccatcc ggccccgggg ccatccggcc
     9781 ccgggattaa acggccccgg gattaaacgg caccggcacc ggccccaggc cccctgacca
     9841 cccggccccc aggactgacc ggcaccggca ccggcccccg gaccaccctg cccccagggc
     9901 tgtccggcac cggcctcagg cccggggggg gccacccggc ccccggccac cggcccggcc
     9961 cccggggccg cctggcctcc ggtgggccgc gacaccctcc tcaccggctc cgctgcgtcg
    10021 cgctgagggc catcgccgcg agacgttccc gcgcggggcg ggtcgcggcg ctgcgctcca
    10081 ggacggcgac ggcccggtcg cggcggcggg tgatctcgcg ctcgacgtac gcgaccgcgc
    10141 ccaggccgac gaggatggcg cggaccgagt cgaggtcgtc ctcggagacg tccgtgccga
    10201 tcctgctgcg gaggaagcgc gccgctgccg ggtcccggtc gtccgcccgt cgcagggccg
    10261 tggccagcag caccgtgcgc ttgccctcgc ggatgtcgtc ccccgacggc ttgccggtca
    10321 cctccgggtc gccgaagacg cccagcacgt cgtcacgcag ctggaaggcg aggccgatgt
    10381 cggcgccgaa ggcccggtac gcggcgacga ggccctggtc ggcgccggcg gcggccgcgc
    10441 cgacgtgcag gggccgctcc accgtgtacg aggccgtctt gtaccggtcc ttgagcagcg
    10501 cggcgtcggc gctctcgtcg ccgcgggcct cggccgccag gtcgaggagc tgcccgcaca
    10561 ggacctcggt gcgcatcgcg gaccagaccg ggccgacgcg ggtcatggcg tccgccggca
    10621 gccccgacgt gcggaccagg tcgtcggccc agacgagggc gaggtcgccg acgaggaggg
    10681 cggcgcccgt gccgtacgcg tcggggtcgc ccgaccagcc ccgttcccgg tgccggtcgg
    10741 cgaaggcgac gtgcgccgag gggaagccgc ggcgggtgcg ggacgcgtcg acgatgtcgt
    10801 cgtggatcag cgccgaggcg tgcagcagct ccagcgccgc gcaggtccgc agcaccgccg
    10861 gggcggtcgg gccgtccggg tcgccgccgg cgcccagcca gccggtccag gcgaacgtcg
    10921 gccgcacccg cttgccgccg cgcagcacgt actcctccag gtcggcgacc gccgtggcgt
    10981 agccctcgcc gatcgccgcg gccccggccc ggcgctcggc gaggaaggtc cgcagcgccg
    11041 cgtcgacggc tgccgtgccg gccgtgacct cggggtggtc gacggtcatg cgcgggtcac
    11101 cgtccgatca ggacggaggc ggcgagcacc accgtcgccc agctgagcag ggaggagtgg
    11161 tacggcccga ggagcgactt cccgtgcagg tcggcgacgg cctcgtggag cggcgcccgg
    11221 cgcacgtcgc gcacgacggc gtcgaggaac cggatgctca ccagccaggc ggcgaggaac
    11281 ggcagcagcc cccacgagaa gccgaacgtc gccggcacgg agacgaggat cagcaccccg
    11341 cccgcgacga gcatcgccag ctgcacccgg aacgcccgga ccagccccag ggcgcgcacg
    11401 taggtgcgga tgccgaagcg cccgtccacg aggtagtcct cgccgtggct ggtgacgaag
    11461 agggaggtca gggccagtgc gaagccgagg acggcgacga ccgaccccca ctccagcgga
    11521 tggccgaagg accacagcac gaacaggccc ggcaggaaca cgcagccgtt ctgcaacgcg
    11581 agcagctgcc acagcccggc gctcttgagg tgcagcggcg gcagggagta ctggaagccg
    11641 atgagcccgg cggcgagcgc cggcagcagc atcccccact gctgggcccg cacggtgagg
    11701 tagagggcga gggccgcgca gacggccgtc gacacggcga tgtgcgccac gacgcgcggc
    11761 acgcccagcc cgtacacggc gtccgactgc cgcgacttca gctgtctgtc ctgctcgcgg
    11821 tcggccaggg cgttcgtcat gttcgcgacc tggaggccgg agatgacgta gaccagggcg
    11881 agcaccgcgt cgagcgacgc gaattccccc caggaacgcg cgcccagaag ggccggtgtg
    11941 aggacgagcg gaacatagac ggggaggaat tcgtagcgcc ggatgacgag cgcgtacttc
    12001 aggcgcgcgg ccagcggggc acgctcgccg ggcacacccc ggggatcggt cagaatggcg
    12061 gcgaatttcg caccgagtgt cgtggcggtg ccagtgctcg acacgagtcc gtcccttctc
    12121 cggtcggagg gaggtgtggg gtgcgtcccg gcgggcggcc ccacccgctc aggcggcgcc
    12181 gaagaccgat gccaccgagt agacgcccgg cgcgggcttg ccgagggcgg ccgtcttgcg
    12241 gccgtactcc tgggcggcgg ggtcggcgag ggtcgcctgg atgtcctcct ggctgcgcca
    12301 ctgggcgagg ttcacgacct tcgtgccgtc cttgccgacg agcacggtcg ccgagacgaa
    12361 cccgggccgg tgccggaaca ccttctcgac gccctcgttg aggagcgcca cgagttcgtc
    12421 ctgcttcgag gcctccacct cgaagacgtt gatgagggtg agcagattgt cttccgtgcg
    12481 aatcaccgtt tcagtcatgc gcggaaacta acaacgccgg aaagccccgg acaacgcccg
    12541 cgttgactca cggcccatgc gcgcaaagac ccggtgcgcg gaattccgtt tcggcgcgcg
    12601 ccgtggtgtg ccgcggcggg cgtcacgggt gtgcggcggg ctttccgccg ggggcgccgc
    12661 ggcgcggcgg gggccggtgc ggccctgcgg gctccggcgg acgtcgtacc gaccggccgc
    12721 tggggggtgc cgccgggccc gggctcggtc ggccgggagg ggcccgggac accttccggt
    12781 cgcgcccggg catgaccggg cagcggtgat gtactagagt tatctcgaca tcgagatatc
    12841 tgctgacgac gcaccgcggt cgcccgtgag ggtaagggtc acctaactga gccttacctt
    12901 agcggatcgg cgagaagccc tggcggcagg atgcggttga acgcgcacat tgatgaagga
    12961 gactgtcgtg tcggcgaaca gcttcgacgc ccgcagcacg ctgcgcgtgg gcgacgagtc
    13021 gtacgagatc ttccggctgg acaaggtgga gggctccgcc cgcctgccgt acagcctcaa
    13081 ggtcctgctg gagaacctgc tccgcaccga ggacggcgcg aacatcaccg ccgaccacat
    13141 ccgggccctc ggcgggtggg actcccaggc gcagccgagc caggagatcc agttcacccc
    13201 cgcccgcgtg atcatgcagg acttcaccgg tgtgccgtgt gtggtggacc tcgccaccat
    13261 gcgtgaggcc gtcaaggagc tcggcggcga cccgtcgaag atcaacccgc tcgccccggc
    13321 cgagctggtc atcgaccact ccgtcatcgc cgacaagttc ggcaccgcgg aggccttcgg
    13381 ccagaacgtc gagctggagt acggccgcaa caaggagcgc taccagttcc tgcgctgggg
    13441 ccagaccgcc ttcgacgagt tcaaggtcgt cccgcccggc accggcatcg tccaccaggt
    13501 gaacatcgag cacctggccc gcaccgtcat ggtccggggc ggccaggcgt accccgacac
    13561 cctcgtcggc accgactccc acaccaccat ggtcaacggc ctcggtgtgc tcggctgggg
    13621 cgtcggtggc atcgaggccg aggccgccat gctgggtcag ccggtctcca tgctcatccc
    13681 gcgcgtcgtc ggcttcaagc tgaccggcga gctgcccacc ggcaccaccg ccaccgacct
    13741 ggtgctcacc atcaccgaga tgctgcgcaa gcacggcgtc gtcggcaagt tcgtcgagtt
    13801 ctacggtgag ggcgtcgccg ccacctccct cgcgaaccgc gccaccatcg gcaacatgtc
    13861 gcccgagttc ggctccaccg ccgcgatctt cccgatcgac gacgagacgc tgaagtacct
    13921 caagctcacc ggccgctccg agcagcaggt cgcgctcgtc gaggcgtacg ccaaggagca
    13981 gggcctgtgg ctggacccgg ccgccgagcc ggacttctcc gagaagctgg agctcgacct
    14041 ctccacggtc gtcccctcca tcgccggccc gaagcgcccg caggaccgca tcgtcctcgc
    14101 cgaggccgcc gagcagttca agcgtgacgt cctcaactac gtcgaggcgg gcgtgaccgg
    14161 cggcgacgac cgcaagccgg gcgtcccgca gcaggagcag ccgcacggcg tggcctcccc
    14221 cgtcgacgag gcgagcgccg agtcgttccc ggcctccgac gccccggcgt acggccacga
    14281 cgacaacggc gccggcgccc cgcagcacga cgaggccacg ggcgaggcgg tcccgtcccg
    14341 cccggtcacc gtcaccgccg ccgacggctc gacgtacgag atcgaccacg gcgccgtcac
    14401 cgtcgccgcg atcacctcct gcaccaacac ctcgaacccg tacgtcatgg tcgccgcggc
    14461 gctcgtggcg aagaaggcgg tcgagaaggg cctgacccgc aagccgtggg tcaagaccac
    14521 cctcgccccg ggctcgaagg tcgtcaccga ctacttcgac aaggcgggcc tcaccccgta
    14581 cctcgacaag gtcggcttca acctcgtcgg ctacggctgc accacctgca tcggcaactc
    14641 cggcccgctg ccggaggagg tctccaaggc ggtcaacgac cacgacctcg cggtcacctc
    14701 ggtcctctcc ggcaaccgga acttcgaggg ccggatcaac cccgacgtca agatgaacta
    14761 cctggcctcc ccgccgctgg tcgtcgcgta cgccctcgcg ggttccatga aggtggacat
    14821 caccaaggac gccctcggca ccgaccagga cggcaacccg gtcttcctga aggacatctg
    14881 gccctccgag gccgaggtga acgacgtcgt cgccaacgcc atcggcgagg acatgttcaa
    14941 caagtcctac caggacgtct tcgcgggcga cgcccagtgg caggcgctgt ccatcccgac
    15001 cggcgacacc ttcgagtggg acccgcagtc cacctacgtg cgcaagcccc cgtacttcga
    15061 gggcatgacc atggagacga cgccggtcgc cgacatcacc ggcgcccgcg tcctcgccaa
    15121 gctgggcgac tcggtcacca ccgaccacat ctccccggcc ggcgccatca aggccgacac
    15181 cccggccggc cagtacctca cggagcacgg cgtcgagcgc cgcgacttca acagctacgg
    15241 ctcgcgccgc ggcaaccacg aggtcatgat ccgcggcacg ttcgccaaca tccgcctgcg
    15301 caaccagatc gcgccgggca ccgagggcgg ctacacccgc gacttcaccc gggccgacga
    15361 aggtgctccg gtgtcgttca tctacgacgc ctcccgcaac tacatcgagc agggcatccc
    15421 gctcgtcgtc ctggccggca aggagtacgg ctccggctcg tcccgcgact gggccgccaa
    15481 gggcaccgcg ctcctcggcg tcaaggccgt catcgccgag tcctacgagc gcatccaccg
    15541 ctcgaacctc atcggcatgg gcgtcctgcc gctccagttc ccggagggcg cgtccgccga
    15601 gtcgctcggc ctgaccggcg aggagacctt ctccatcgcg ggcgtcaccg agctgaacga
    15661 gggcaccacg ccccgcacgg tgaaggtcac caccgacacc ggcgtcgagt tcgacgcggt
    15721 cgtccgcatc gacacccccg gcgaggcgga ctactaccgc aacggcggca tcatgcagta
    15781 cgtgctgcgc aacctgatcc gcggctgagg caccacccca cccgcggccg agggccgcac
    15841 cccgtcgcgt acggggtgcg gccctcccgc cgtcacgggg tccgtggcgg ggggagggcc
    15901 gcggtgctca cgcggcaacc gccgggcccg tgccgaccag ccggtccagc agtccgtcgg
    15961 gcgtcgggta cggctcctcc cggggcagca gccgccgtgc gccgtcgagg tcgcccgcgc
    16021 ggaccagggc gtggacctcg tgggcgagcg gcgtgacgtc ggtgatcgac accgtccact
    16081 cgtccgcgta ccgccgggcc gcctcgcccg ccaggcccag ctggagggac cggtacggca
    16141 gcgggcgcag gtgcaggtcg cgctccgggt cccactggac gcgggcgggg gcgtcgcgca
    16201 gctcccgccg ccacgcctcc ggggaggcgt gcagcccggc gcggtagtgc gagaggcagg
    16261 cgtggcgcag cgcccactcg aaaccggccc ggcggatctc gacggcgagg acggtctcct
    16321 gggcctcctt ggccgcccag ccgcagcggt acatcatcca caggaacgac ggcttgatcc
    16381 acgtcatccg gtcccgcttc caggacgccg ggaaccgccc ctcgcgcgcg gcgggcaggc
    16441 cgatggcggg ggagtaggcc tggtagacgg tgacggtcgt gtccgtgcgg agcgcgcgga
    16501 cgcgctggtg cggttcttcc atggccccag gctgccgccg gcgcggggcc cgggccagcg
    16561 atttatcgcc cgccgcgacg ccctggcgcc acccgcccgg cgtacgtccc gccgcacccg
    16621 cgcccgccgc ccgccgcgag gccctggcgc cgcccgcgcc cgccgcgcgc gtgcccgccc
    16681 gcgctcccgc cggtctcacc cgcggggtgg ccgggccagg agttccacct ccgccagctc
    16741 ccggcccgct cccgctcccg cgtccgcggc gaccagccgg taggccctgt acgcccccgg
    16801 ccgggccacc gtgaacaccc gcgtctggcg gtcccagcgg aagacctcgc ccgaccggcg
    16861 gtccacctcc cgccagcggg cgccgtccgt cgagccctcc aacacccagc cgtccggcgc
    16921 ggccgccgcg gccgcggagg tcagggtgta ctggaccgcg cggaccggcc ccggcaccgg
    16981 cagctccacc gcgcccgaca ccggccccgc cgtcgccgac gtgtcgtcga acagcgggcc
    17041 gggacccgac agggcgtcgc gccgcggcac gggcacgcgg tcgtcccggg tgacggaggc
    17101 gggcgccgcg tccgcgcccg tgccccacgt cgagggccgc ggccccatgt cgaactccag
    17161 cgtcccgccc cgcgcgagga gcccgtgcgg cagcgccgtc gacgtccact gccggccgtt
    17221 gacccgcagt ccctgcacgt agacgttccg ggggctgttg cgcggggcct tgacgacgag
    17281 caccgccccg tcgtcggtgc gcaccgtcgc cttggtgaac agcggcgacc cgacggcgta
    17341 ctcgcccgcg cccatcacca gcgggtagaa gccgagcgcg gagaacaggt accaggccga
    17401 ctgctcgccg ttgtcctcgt cgccgtggta gccctggccg atctcgctgc cgacgtacag
    17461 ccgggacagc acctcgcgga ccttctcctg cgtcttccac ggctgccccg ccgcgtcgta
    17521 catgtacgcg acgtggtggg cgacctggtt ggagtggccg tacatgccca tccgcacgtc
    17581 ccgcgcctcc gtcatctcgt ggatgacgcc gccgtacgag ccggcgaact cgggcgcgcc
    17641 cgtctccggt gtcgagaagt acgcgtcgag cttcgccgcg agaccggcgc gcccgccgta
    17701 caggttggcc aagccccggc tgtcctgcgg ggcggtgaag gcgtaccccc agccgttggt
    17761 ctcggtgtag tcgtaccccc acacgcgcgg gtcgtacgag gccgacggca cccgccaccg
    17821 gccgcgcgcg tcgcgcccct ggaagaagcc ggcctccgcg tcgaagagcg ccacgtagcc
    17881 gcgcgcccgg tccaggaagt acgcggcctc ctccccgtag cgggcctcgc cggtcctgcg
    17941 gtgcagctcg cgcgccatcc gcgccaggcc gaagtcgttg acgtacccct ccatcgacca
    18001 ggacaggccc tcgtgcgtct ccgtcgaggc gtacccggtg aagggggagg tggccatgcc
    18061 cttgcggccc acgccccggc ccggcgggag caccgtcgcg ttcttcagcg ccgcctcgta
    18121 cgccgcctcc gcgtcgaagc ggacgccctt gacgtacgcg tcggcgaacg ccacgtccga
    18181 ggacgtgccg gtcatcaggt cggcgtaccc cggcgacgac cagcgggaga tccagccgcc
    18241 gtcccggtac tgctggacga agccgtccac cagttccccc gcccggcgcg gggtgaggaa
    18301 ggagtaggcg ggccacgtcg tccggtaggt gtcccagaag ccgttgttga cgtacacctt
    18361 cccgtcgacg atcttcgcgc cggtgtgcgt cggggtgtcc gggccggtct gcggggagaa
    18421 cgggctggcg tagcgccacc ggccgtcgac ccgctcatgg ccggagttgg ggtacagata
    18481 cagccggtac aggccggagt agagcgtcgt gagctggtcg cgcgtcgcgc cctccacgcg
    18541 cacccggccg aggaggcggt cccactgcgc ccgcgccgcg gccgccaccg cggcgaacgg
    18601 cgtgcccgcc gggatctccg cggcgaggtt gcgccgcgcc tgttccacgc tgatcagcga
    18661 cgtcgccatc cgcaggtgca ccgtccggtc ccggcccgcc gcgaaccgca ggaagccccg
    18721 gacgccctcc gccgacgagg cggtgaccgg cgcgtcgaac acaccgtgga cgaacatccg
    18781 cgtcgcgccc gtcgacagac cgctcttcac gtccgagtag ccggtgaagg agctcgtcgc
    18841 cggatcgagc gtcagcccgc cctcctgcgt gatgttgtcg aagaccaccg acgcgtcgtc
    18901 accggggaac gtgaaccgca tcgtcgccgc gtggtccgcc ggggcgatct ccgccgtgag
    18961 gccgttctcg aagcggaccc ggtagtggtg aggtcgcgcc gactcgttgc cgtgacggaa
    19021 ctccagcgcg cgggcggccc gttcggtggg tggcgccccc ggccccggcg ccgccgacgg
    19081 catcacctgg aacgtctgcc ggtcgcccat ccaggggctc ggctcgtggc tggcgctgaa
    19141 cgcctggagc gcgggcaggt tgttcgcggt gttgccgcgc gcgtactcgt acagccagct
    19201 cttcgacgcg gcgttcgtca ccggcgtcca gaagttgaag ccgtgcggca cggccgtcgc
    19261 ggggaaggtg ttgccgcgcg agaaggcgcc gctggagtgg gtcccgcgca ccgtcgagac
    19321 gtacgcggag ggatggacgt gcgccggttc gggcgccgcg cggctcagcg tgacgtcgtc
    19381 gagccacccc tggaagcggg cgggtccccg cggcgcgtcg tacgccacca ggatccggtc
    19441 cacgacgcgg ccggcggcga ccgcgccgat gccggccgtg acctggttcc actggttggc
    19501 gtagaggcgc ttcgcggcgg cctggccgcg cggcgtgagc accccgccgt ggctgtcggt
    19561 ggcgcgcagg ccgctgaggt aggtcccgtc ggtgaaggcc aggtccacgg cgacgtgcgt
    19621 cgcggggtac gtcaggtcgg ccccggtgcc gccgggcccc gcgggcaggg aggggtggat
    19681 ccggtacgac agctccgtgg tgggcccgac cgcgacgtgc acgtcgaaga ccttgttgta
    19741 cgagtgcccc ggccccgccg cccggtgcgt cccggcgtac cgcagcgccc gcaggccggt
    19801 gaaaccggcg tgcgccttgg cggtggggga gccggccggg ccccggtcga cgtggctgcg
    19861 catggtccgc ggcgcggggg ccgtgccgtc cccgtccgag aggtggacgt cggcgagttg
    19921 cagggtggcg ggggcgccgt tgttggcggt gatttccagc cggtagtgcg cgtaccgggt
    19981 ggtgttggcg aagtggtacg tgcgtgtccg gaagcgttcc gggaacgtct cgttctcgcg
    20041 ggtgtcgagg ggcgtccagc gcgtgccgtc ggcggagccg tggagcgtcc aggcgcgcgg
    20101 gtcgcgcgcg gcgtggtcgt tggcggaggt gagggcgtag gagacgaccg ggagcggttc
    20161 ctccagcgtg aattcgagcc aggcggtcgg ggctaaggtg agccatttcg tggtgggttc
    20221 ggagtcgagc agattctcct tcgtctcgcc ggcctccgcg tgctccccgc tggcccgcac
    20281 cccggtgacc cggtccgtca cgtcgccggg gatgcccgcg gcgaaggcgc cgtccacacc
    20341 ccgggcccgc tcccggccgt ccgggccggt ctcgacggtg tcgcgccagg tgggcggggc
    20401 ctcgtcgggt tcgaacgagg tggtgaactc ctgtgccggg gccgcaggtc gggccggtga
    20461 cgcctgtacg gccgggggcg atccggccac gagcagcgag acggccgcca ggacgacggc
    20521 cgtgcgaaga ggtcgtaacc gcatccgacg ctccctccga tcgcgccagg acaacgttgt
    20581 caactcaagg gcgcggggtc cagtagggag cgaggtggaa gagggtgtca agggttccgg
    20641 cggggtggtg cggcgcgatt cattccttcc ggtgatcgaa tcgagcttcg attcacgccg
    20701 cgctgaaagg aattcccccg aggtctcaac tagggaaaga ctcctgccga atactgttat
    20761 cgatcttgcc ccgtcgacct gaagtggact atacctgtcg gcgtccgcgc cggccgttcc
    20821 cgaacggccg ggcggtgcgc tgctccctgc acgaaccggc acgacccagc tgcacgagac
    20881 cgcggtggcg gggcccttcg cctctggcga gtcgtacggg gcgaccggcg caccgcctga
    20941 gtcctggaga aggcgaggac ttgagcatgg gatccacctc cgcccgcaac gacggcgacg
    21001 acggttccac tcccgagggc ggccgcggcc gcgcgggcca cggccgccga gaactgctgc
    21061 ggcggtccgc cgcgctcggc ctgatcgcc
//
