LOCUS       NZ_CP102332            22696 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Streptomyces changanensis strain HL-66 chromosome, complete genome.
ACCESSION   NZ_CP102332
VERSION     NZ_CP102332.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces changanensis
  ORGANISM  Streptomyces changanensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6817869)
  AUTHORS   Wu,H. and Han,L.
  TITLE     Streptomyces changanensis sp. nov., an actinomycete isolated from
            soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6817869)
  AUTHORS   Wu,H. and Han,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2022) College of Forestry (Academy of Forestry),
            Northwest A&F University, Northwest A&F University, Yangling,
            Shaanxi 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.9; Pilon v. 1.24
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 187.45x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024600715.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 19:18:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,071
            CDSs (total)                      :: 5,982
            Genes (coding)                    :: 5,812
            CDSs (with protein)               :: 5,812
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 170
            CDSs (without protein)            :: 170
            Pseudo Genes (ambiguous residues) :: 0 of 170
            Pseudo Genes (frameshifted)       :: 70 of 170
            Pseudo Genes (incomplete)         :: 131 of 170
            Pseudo Genes (internal stop)      :: 9 of 170
            Pseudo Genes (multiple problems)  :: 37 of 170
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:13:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 555798
            Orig. end                         :: 578494
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102332.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22696
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="5"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22696
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22696
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12696](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12696
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            1917..4250
                     /locus_tag="NRO40_RS02415"
                     /old_locus_tag="NRO40_02415"
     CDS             1917..4250
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240736.1"
                     /locus_tag="NRO40_RS02415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02415"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_058940293.1"
                     /transl_table=11
                     /translation="MSGDEQRVEALAGTVEQLRRDLDLAQQSADARALIGIATGILVER
                     GHGGPMESFRHLEELAQAARLPLLELAADIVNGAAGDDVAAAAPVATAAARQVLAPEQS
                     GPGEVLRMRTAEAGSLTGDAQAVVDSMLDQALAPLGAKAAALWAAIPGGALVLAAHAGF
                     VHGEAQRWHYVPPGVGTLAQRAVAERRPLWFGDLPTDVPGIGQRRGTTGARAVLPAEVS
                     GRVMGVLEVCWPHTQPPLSGMAARQLDALADLCAHTLPGSEAALAEPRTPDNPAGPLVE
                     LADSLLDPTMVLRPVLDDRDQVTDFTIAYANERFSDIAGRARSTLIGMRLLEAYPLTAR
                     EGGLYEYVLRVHATGEAFHAERMALSALVGEVPLTSVAAVGIGRYGDSVLLTWRLEDEA
                     TRLAALLQHAQRLGRIGGFEENVVSGEITWNSQLFALFGLPQGSSPVPLERLHHHAHPD
                     DAVAIGRFLRAVLYHRHAASTAVRLQRADGVVRHIRIVAEPVTGPDGALLAVRGAYQDV
                     SAQHWTEVALAATRDRLADSEQRVAERNRLALQLQQAIMPPTSAPVDLADLRVAVRYRP
                     AEEGHLVGGDWYDAVLLPTKKVLLVVGDVAGHGIEAATGMVVLRNALRGLAATGSGPAQ
                     LLGWLNTVAHHLTEHVTATAVCGVYDPETRVLRWARAGHPPPVLVRDGEAFTLPLPRGL
                     LLGAIPDAEYEEHRLPMELGDRLFMYTDGLIERRDRSVEHSLQQLLPIAGQSTRDLGEH
                     LDLLLTHSRSDTDDDTCLIGVQVG"
     gene            complement(4647..5498)
                     /locus_tag="NRO40_RS02420"
                     /old_locus_tag="NRO40_02420"
     CDS             complement(4647..5498)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991309.1"
                     /locus_tag="NRO40_RS02420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02420"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_058940294.1"
                     /transl_table=11
                     /translation="MTVIAAGTSTAADREGRIPGDVEPQRLSPQDARELSRTFFDRLAT
                     LEEGTHDHQYVRNTLIEMNMSLVRFAARRFRGPGSDMDDIVQVGMIGLIKAIDRFDLSR
                     EVEFTTFAMPCILGEIKRFFRDTSWAVHVPRRLQEARQELVRATDELTSRLGRDPKVSE
                     LADLTGMTEDEVRKAQVAAAGYSSASLDAAVRGDSPDGEAVLADFIGVEEHALELIEDF
                     HSLAPLVAELDERDRTILHLRFVEERTQAQIAEVLGVSQMHVSRLLARTVRRLREGLLA
                     TS"
     gene            complement(5579..5797)
                     /locus_tag="NRO40_RS02425"
                     /old_locus_tag="NRO40_02425"
     CDS             complement(5579..5797)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009713141.1"
                     /locus_tag="NRO40_RS02425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02425"
                     /product="DUF5133 domain-containing protein"
                     /protein_id="WP_306674897.1"
                     /transl_table=11
                     /translation="MAHPAVLSKLAEEYASLEARRAQADGPEVRRRMEDVAYTLCVSTG
                     TRDVEDALAAVRRRLAEVHGNDPVLAL"
     gene            complement(5961..6377)
                     /locus_tag="NRO40_RS02430"
                     /old_locus_tag="NRO40_02430"
     CDS             complement(5961..6377)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955605.1"
                     /locus_tag="NRO40_RS02430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02430"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_058940296.1"
                     /transl_table=11
                     /translation="MTTAREIMTEGAECVGENESVLDAARKMTDLGVGALPICGADDKL
                     KGMLTDRDIVVKVLGAGKDPASCKAGELAQGEVVTIGADDDADEILRTMTSHKVRRLPV
                     IDGHELVGMVAQADVARALPEPKVGDLLEALSTD"
     misc_feature    6518..6531
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.06"
                     /tool="antismash"
     gene            6579..7166
                     /locus_tag="NRO40_RS02435"
                     /old_locus_tag="NRO40_02435"
     CDS             6579..7166
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131958.1"
                     /locus_tag="NRO40_RS02435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02435"
                     /product="DUF6328 family protein"
                     /protein_id="WP_058940411.1"
                     /transl_table=11
                     /translation="MTMTEPPVDRGTRTPPACRTGDDSVTRDDVTPDDRPESARDRVNR
                     RWQEILQETRVAQTGVQILFGFLLSVAFTPVFRDLGTFDRAVYVVTVVTGASATAALIA
                     PVSLHRFLSGQRMKDELVGTAHKLMMCGMVLLALTIGCTLLLILHVVVPGLLAELLVGG
                     VMLWFALCWYALPLWLRHRSGRRGDDDPAARG"
     gene            7305..8396
                     /locus_tag="NRO40_RS02440"
                     /old_locus_tag="NRO40_02440"
     CDS             7305..8396
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1165: carboxylate-amine ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018562860.1"
                     /locus_tag="NRO40_RS02440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02440"
                     /product="glutamate--cysteine ligase"
                     /protein_id="WP_058940297.1"
                     /transl_table=11
                     /translation="MRSVGVEEELLLVDGRTGEPRALSAAVLAAASRDPQGNEEVFESE
                     LQRQQLEFATKPQTDMRDLEEEIRRWRAEAARHAEGVDASVAALATSPLEVSPTIGNDE
                     RHQWLKEHFGLTAQEQLTCGCHVHVSVDSDDEGVAVLDRIRPWLPALLAMSANSPFWQG
                     EDSGYASYRNRVWGRWPSAGPVEVFGSADRYHEQVADMVASGALKDEGMVYFDARLSRS
                     YPTVEIRVADVCLDPSTTALIATLIRGLVDTAAREWRDGVPPTRHGVALLRLASWRAAR
                     SGLEDQLIHPVTMRPAPAEAVVRALFDHVRDALEENGDLLGAQDALAGLLATGNGARVQ
                     RTLLHRTGSLQEVVAECVRRTLA"
     gene            8683..9246
                     /locus_tag="NRO40_RS02445"
                     /old_locus_tag="NRO40_02445"
     CDS             8683..9246
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS02445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NRO40_02445"
                     /product="hypothetical protein"
                     /protein_id="WP_058940298.1"
                     /transl_table=11
                     /translation="MTPCRIPPDHDPDVIRTVHRVGLTLGVSDKVMLAAFEAGWVESHM
                     NNLDCGDKDSLGVFQQRPSQGWGTPEQIRDVPYAAERFFRGAMGVERRSPGLSAGRTAQ
                     EVQRSAHPDRYDAAEGKARALLREAEAAAAAAPPRVGAAGIPAPTEPAPPRAVPAQAIP
                     PSAGQARRAGQARGRSADGAAAGQ"
     misc_feature    complement(9265..9274)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            9872..9982
                     /locus_tag="NRO40_RS02450"
                     /old_locus_tag="NRO40_02450"
     CDS             9872..9982
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656044.1"
                     /locus_tag="NRO40_RS02450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02450"
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_107114980.1"
                     /transl_table=11
                     /translation="MKKAYEAPTLARLGSFRKTTGLLQRSGNDRLIFSKN"
     gene            10001..11857
                     /locus_tag="NRO40_RS02455"
                     /old_locus_tag="NRO40_02455"
     CDS             10001..11857
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988505.1"
                     /locus_tag="NRO40_RS02455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02455"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_058940299.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.6e-48, bitscore:
                     163.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELHESAGTGHGGAHFAVFTDRADAAAAARSFRRPGTRVLAHAS
                     GRPWLIGRWDDDELVTARAGSAALALVGTCPVDAAEVRRVAGRLRDLADLDAWVRSLPG
                     SFHLVAALDGRTRVQGTASGLRLVHHADLGGVTVAATRADWLAAALGRAPDRAQLAVRL
                     LWPVPHPLSEASLWEGVHAVPPDEALVVAADGRGVRRSRWWMPPEPVQALAEGAPRVRQ
                     ALAEAVDARTRGGGVVSCDLSGGLDSTSVCFLADRSPARVVASTWPGRDPADTDLEWAR
                     RAARALPDVEHVVWDADASPLVYDDLLGIDDLLDEPTIGVMDRSRVLHHLPGMARRGSR
                     IHLTGIGGDHVAWCSEAYYHRLARTRPLFALRQLRGFRALWQWPLGGTLRALADNRPYG
                     RWLRDCTVDLRGARPATVTTSLGWGMPPRLFDWVTSDAAELAGRALRDAAAGARPLHPD
                     RGLHTDLEQIRGCTRIIRQWDHMAARTGLPMASPFLDDRVIEACLAVRPAERVSPWRYK
                     PLLTAAMRGIVPEECLRRTDKAAASMDAADGLREHRADLMALWEDSRLERLGLVDGVAL
                     RRLAQRPSTPELHDGVLYPTIAAEVWLRGLEPARDGTAPARP"
     gene            12008..12262
                     /locus_tag="NRO40_RS02460"
                     /old_locus_tag="NRO40_02460"
     CDS             12008..12262
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309239.1"
                     /locus_tag="NRO40_RS02460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02460"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_058940300.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.5e-22,
                     bitscore: 77.8, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2e-14, bitscore: 52.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALRFSADVSTAKTDYGTVLLDERGGEYWELNPSATLVVGVLMSG
                     GDEDAAAAALVAEFDVDPQGAARDVAALVGELRAAGLAA"
     aSDomain        12011..12256
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_NRO40_RS02460_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="7.20E-25"
                     /identifier="RREFam002.1"
                     /label="NRO40_RS02460"
                     /locus_tag="NRO40_RS02460"
                     /protein_end="83"
                     /protein_start="1"
                     /score="77.8"
                     /tool="antismash"
                     /translation="ALRFSADVSTAKTDYGTVLLDERGGEYWELNPSATLVVGVLMSGG
                     DEDAAAAALVAEFDVDPQGAARDVAALVGELRAAGLA"
     gene            12259..12696
                     /locus_tag="NRO40_RS02465"
                     /old_locus_tag="NRO40_02465"
     CDS             12259..12696
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988507.1"
                     /locus_tag="NRO40_RS02465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02465"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_058940301.1"
                     /sec_met_domain="PF13471 (E-value: 4.5e-26, bitscore: 89.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPSALERPEGVPFARRCAARLVLLPALALSLLPPRRIRGVLDL
                     LRRGAAPASAAQAADARDAVCAVSLRCAGPKGCLPRSLGAALLCRLGGTWPTWCTGVRV
                     VPPFTAHAWVEAEGRPVGEDAPDDYFTRLMAIGPAPRPPRR"
     gene            12878..13801
                     /locus_tag="NRO40_RS02470"
                     /old_locus_tag="NRO40_02470"
     CDS             12878..13801
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="NRO40_RS02470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02470"
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="WP_306674898.1"
                     /transl_table=11
                     /translation="MLAREAVERGAGGRAFGSVLLLLAAVFAAEASTGAVGRYLLERTG
                     EGVVRRLRHGLVDRFLRLEVREYHRHRAGDLTSRVTADTTVLREVVSQALVDLVTGALV
                     AAGAIALMAWLDPLLLLVALTVVVASMLVASMLKGIRAASAHTQDSVGAVAAELERALG
                     ALPLVRVHRAEEREAAAIGTPARCRRPRAGTAGPGPAGGATGPPRPGPRRRPCPRHGHG
                     GHSRSRCHARHGVRRPPRPRLRPAGGRYRCGGTRTRPARRALRVHVGPARPARGVADGA
                     VPAPGGPGRYLGCGQEHPVRPGGAVL"
     gene            13704..14312
                     /locus_tag="NRO40_RS30505"
     CDS             13704..14312
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012235.5"
                     /locus_tag="NRO40_RS30505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_306674851.1"
                     /transl_table=11
                     /translation="MSLTVPSRRQVALVGTSGAGKSTLFALVARFYEPDAGTLSFDGVP
                     AAELGRSDCRARIAVVDQNTRVVHGTLWDNITYGAPDAGEAEVRRVVDLARLGAVVERL
                     PGGLRGAVGERGATLSGGERQRVALARALLTRPSCSCRAGAPTGGGGGRLPRYPHRPGR
                     NRRLPFIAPLKGRHRVAKQGETGAFSSHSSWVSAQVGTA"
     gene            14371..15816
                     /locus_tag="NRO40_RS02475"
                     /old_locus_tag="NRO40_02475"
     CDS             14371..15816
                     /EC_number="1.2.1.12"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009333304.1"
                     /locus_tag="NRO40_RS02475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02475"
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="WP_058940304.1"
                     /transl_table=11
                     /translation="MTVNEDSFTSWKNREEIAESMIPIIGKLHRERDVTVLLHSRSLVN
                     KSVVSILKTHRFARQIAGEELSVTETMPFLRALTTLDLGPSQIDIGMLAATYRTDDRGL
                     SVEEFTAEAVAGATGADKIERSEPRDVVLYGFGRIGRLVARLLIEKAGSGNGLRLRAIV
                     VRRGGEQDIVKRASLLRRDSIHGQFQGTITVDEANSTIVANGNAIKVIYAGDPSEIDYT
                     AYGIKNAILIDNTGKWRDREGLSQHLRPGIDKVVLTAPGKGDVPNIVHGVNHDTIKPDE
                     QVLSCASCTTNAIVPPLKAMADEYGVLRGHVETVHSFTNDQNLLDNYHKADRRGRSAPL
                     NMVITETGAASAVAKALPELKAPITGSSIRVPVPDVSIAILSLRLGRETTREEVLDYLR
                     NVSLTSPLKRQIDFTTAPDAVSSDFIGSRHASIVDAGATKVDGDNAILYLWYDNEFGYS
                     CQVIRVVQHVSGVEYPTYPAPAV"
     gene            16270..18522
                     /locus_tag="NRO40_RS02480"
                     /old_locus_tag="NRO40_02480"
     CDS             16270..18522
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.5"
                     /locus_tag="NRO40_RS02480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02480"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_058940305.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.1e-52, bitscore:
                     176.6, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVIAYYLHEGEAAEAVRVLRNTSVTSGFVVGDADADDLPRLAAA
                     GLLVDPLDPGPAAVPPSPARATLRAHDTGTGAGADAREGSGPEPLPPEPGVSAQWVLHL
                     GEPLLEEYRAGIVSQGVVLLRALPGGAYLVTATPEQAEDVLNLPYVRSVRHHDPDAAAP
                     LRLSAGELTEVETEGHGTTALRTWDLVTADADARAGVRAWLLARADAHGPEIVAEGGRR
                     LRVRLPAGSPLEEEVARVPGVLAVTEYVEPKLFNDVARALLGVTPAEAAGGLPLTGRGE
                     VVAVADTGFDTTHPDFDGRVVGTAALGRPGDSSDPHGHGTHVAGSVLGDGSASQGAFRG
                     VAPEAKLYFQSVQDRHGGLGGLPASLEDLFEPAYQAGARVHNDSWGAATEAAYTANSDD
                     VDAYVRRRPDMLVVIAAGNEGTAAARLHAQEGFVDWLSLGSPGSSKNALTVGAARTSRA
                     DGPGGDLTWGEWDRGTPFPDDPIAGERVSGDPEALAAFSSRGPCDDWRVKPDVVAPGTD
                     ILSTRAAGAPRQSFWGLHDNPRYAFMGGTSMATPLVAGCAALVREYYVRERGTSPSAAL
                     VKATLINGARRLTAPDATAPDPHFHQGFGAVHLPSTLPNPAVPDLVLDFADTWQTPARQ
                     LARTGDVSRFTVEVAAGAPLRLCLAYTDLPGRSLQNDLSVLVETPDGVRHAGNDTLPNR
                     LLQTDSTNNVEVVRLPDAPQGRYLIQVFARNLLEGPQDFALVVTGRLTGPLRRTTG"
     gene            complement(18749..19483)
                     /locus_tag="NRO40_RS02485"
                     /old_locus_tag="NRO40_02485"
     CDS             complement(18749..19483)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552876.1"
                     /locus_tag="NRO40_RS02485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02485"
                     /product="restriction endonuclease"
                     /protein_id="WP_232790926.1"
                     /transl_table=11
                     /translation="MPGARRAGWRDVVLALGLVGVAVGGLALLVRTVWHVPDGAFGPVL
                     LLVMVVLAAVVAGRAATRRAPGRAAIPAQAPPPGPDEVTAVLPVEGAAPAPPVPRLDGD
                     SVDHEEVDAYGFEHTVAALCVRDGCTRTEVSGGPGDLGADVVATAPDGRRLIVQCKQYA
                     ADNPVGSQDLQRFGGTCFAVHGAEVAVVVTTSTFTAPAVEYAETIGIVCVDGEALAAWT
                     DGRTPPPWEDPAAAPEPPDEAG"
     gene            complement(19736..20086)
                     /locus_tag="NRO40_RS02490"
                     /old_locus_tag="NRO40_02490"
     CDS             complement(19736..20086)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0070064 - proline-rich region binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019844.5"
                     /locus_tag="NRO40_RS02490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02490"
                     /product="SH3 domain-containing protein"
                     /protein_id="WP_058940306.1"
                     /transl_table=11
                     /translation="MRTPTLLRTRAGLATAAAVALTALTVGAGTAEAAGSHISSNSGGA
                     NLRTCASTSCGSLGYLTNGTGVSMQCWLDSQWVYPPSANYASNRWFRVSSHKGTGYVHS
                     SLVANQTAVGHC"
     regulatory      20482..20663
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            20693..21739
                     /locus_tag="NRO40_RS02495"
                     /old_locus_tag="NRO40_02495"
     CDS             20693..21739
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004981376.1"
                     /locus_tag="NRO40_RS02495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02495"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_058940307.1"
                     /transl_table=11
                     /translation="MYDGSSRPPFPTPARARGRALGAAALAAVLSATLLSGCGTSRGAD
                     DGRPSAAARPAKGFPVTVDNCGTRTTYDRPPERVVTIHQHPAELLLALGLKDRMVGTAF
                     PDSAVLPQYRKDFAAVPRLAEKEPSFETVLDAEPDLVYGGYASAFDDKAGRSRAAFRDA
                     GIDTYLNREYCGGRSVSMRDTYEEIRTLGSIFGVPERADALVADLRSRIDEATRAVKGA
                     PQVPVFVYDSGDKAAFTAGGKGLGTEIIRLAGGRNVFADLDEVFGDVSWEQVVARKPEV
                     IAIYDYAGAGGVEQKKRFLLAQPALADVPAIRNKRFVVLPLTATLVGVRPPYAVGDLAK
                     ALHPERFR"
     misc_feature    complement(21819..21835)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 18.71"
                     /tool="antismash"
ORIGIN
        1 gcccgcaccg acgagctgct ggaggagtcg cagcggctga ccgccgaact ccaggcgcgc
       61 tccgaggagc tccaggagca gcagcaggag ctgcgcaagt ccaacgcgga cctggaggag
      121 aaggccgcgc tgctcgcggc gcagaaccgg gacatcgagg cgaagacgca ggagatcgag
      181 caggcccgcc aggagctgga ggaccgcgcc cggcagctgt cgctggcgtc gaagtacaag
      241 tcggagttcc tggccaacat gagccacgag ctgcgcaccc cgctgaacag cctgctgatc
      301 ctcgcccagc tcctcgcgca gaaccccacc cgcaacctca cgcccaagca ggtcgagtac
      361 gcgggggtca tccactccgc gggctccgac ctgctccagc tgatcaacga catcctcgac
      421 ctgtccaagg tcgaggccgg gaagatggac atctcccccg agcaggtccc gctgcggcgc
      481 ctcctcgact acgtcgaggc gacgttccgc ccgatgacca cgcagaaggg gttggagttc
      541 ctggtcagcg tcgcgccggg ggtccccgac gagctggtca cggacgacac ccgcatgcgg
      601 caggtgctgc gcaacctcct gtcgaacgcg gtgaagttca ccgaggccgg cgccgtggag
      661 ctgcgcatcg cgccggcgac cgaggacgaa ctgcccgagc agatgcggga ccacggcccg
      721 gccctcgcct tccacgtcac cgacaccggc atcggcatcg ccgaacacca gctggagtcc
      781 atcttcgggg cgttccagca ggcggacggc accacgagcc gcaagtacgg cgggacgggc
      841 ctcgggctct ccatcagccg ggagatcgcc cacctcctcg gcggcgccgt gcacgccacg
      901 agcgccctcg gcgagggcag caccttcacc ttctacctgc cggtcgcccg ctacgccccc
      961 gccggcccgt cggacaagga ccagccgcag atcacgcagc aggccgcccg gtccgggcag
     1021 gacgcgtcgt ccggcgcgcc cggccggctg ccgggccgcc gccgcgtcct cgtcatcgag
     1081 gaccggccac ggggactgct gtcgctcgtc gccgagagcg ccgtcgccga gctggccgac
     1141 aacaccggcg tcgccgactc cctgcccggc gcccacgtgc gcacggccgt cggccccgag
     1201 gaggcggccg cggcgctcgc cgccgagccg tgccactgcg tggtgctcgg gctcgacatg
     1261 cccgacggcg ccgccatgcg cttcctcgcg gccgtcggcg gggaccccgc gctgcgccag
     1321 gtgccggtgc tcgcccacca cacccggcgg ctggaggagg accagaagcg ccagctggag
     1381 acctgggcga cggacaagcc ctgggagctg ctgcccagcc tggacgagct gcgcgagcgc
     1441 atcgccctgc acctgacggc cgaccacccg gcggacgtgc tgccccgcgt gcacggcccg
     1501 gcggccgccg cggtggacgg cgccggggcc ccgggcgaca gcgacctcgc gggccgggtg
     1561 gtcctggtcg tcgacgacga cgcccgcaac gtgtacgcgc tgaccggcat gctggagatg
     1621 cacggcatgc gcgtcctgca cgccgagaac ggccgccagg ggctggagat gctcacgaac
     1681 aacccggacg tcgagctgat cctgatggac gtgatgatgc cggagatgga cgggtacgcc
     1741 gccaccgccg ccatccgcgc catgcccgac cacgccgatc tgccgatcat cgcggtgacc
     1801 gccaaggcca tggccggtga ccgcgagaag gtcctcgcgg cgggggccaa cgactacatc
     1861 accaagcccg tcgacgcggc cgcgctcgtg gaccgcatgc gtcgctggct gcgccgatga
     1921 gcggcgacga acagcgggtg gaggccctgg ccggcaccgt cgagcagctg cggcgcgacc
     1981 tcgacctcgc gcagcagtcg gccgacgccc gggccctgat cggcatcgcg accggcatcc
     2041 tcgtcgagcg gggccacggc gggccgatgg agtccttccg gcacctggag gaactggccc
     2101 aggcggcgcg gctgccgctg ctggagctgg ccgccgacat cgtcaacggc gcggcgggcg
     2161 acgatgtcgc cgcggcggcg ccggtggcga ccgcggcggc gcggcaggtc ctcgcccccg
     2221 aacagtccgg ccccggcgag gtgctgcgga tgcgcaccgc cgaggccggg tcgttgaccg
     2281 gcgacgcgca ggccgtcgtg gactccatgc tcgaccaggc gctcgcgcca ctgggggcga
     2341 aggccgccgc gctgtgggcg gcgatcccgg gcggcgcgct cgtcctggcc gcgcacgccg
     2401 gcttcgtcca cggcgaggcg cagcgctggc actacgtacc gcccggtgtg ggcacgctcg
     2461 cccagcgggc cgtcgccgag cgccggccgc tgtggttcgg cgacctgccc accgacgtgc
     2521 cgggcatcgg gcagcggcgc ggcaccaccg gtgcccgggc cgtgctgccc gccgaggtgt
     2581 ccggccgcgt catgggtgtc ctggaggtgt gctggccgca cacccagccg ccgctgtccg
     2641 gcatggcggc ccggcagctc gacgccctcg ccgacctgtg cgcccacacc ctgcccggct
     2701 ccgaggcggc cctcgccgag ccgcgcaccc cggacaaccc cgcgggcccg ctggtggagt
     2761 tggccgacag cctgctcgac ccgacgatgg tgctgcggcc cgtgctcgac gaccgggacc
     2821 aggtcaccga cttcaccatc gcgtacgcca acgagcgctt cagcgacatc gccggccgcg
     2881 cccggtcgac gctgatcggc atgaggctgc tggaggcgta cccgctgacc gcccgcgagg
     2941 gcgggctgta cgagtacgtg ctgcgcgtcc acgccacggg cgaggcgttc cacgccgagc
     3001 ggatggcgct gagcgccctg gtcggcgagg tgcccctcac gtcggtggcg gccgtcggca
     3061 tcggccggta cggcgattcg gtgctgctca cgtggcggct ggaggacgag gccacccggc
     3121 tcgccgcgct gctccagcac gcgcagcggc tgggccggat cggcggcttc gaggagaacg
     3181 tcgtcagcgg cgagatcacc tggaacagcc agctgttcgc gctcttcggg ctgccgcagg
     3241 gctcctcgcc cgtgccgctg gagcggctgc accaccacgc gcacccggac gacgccgtgg
     3301 ccatcggtcg gttcctgcgg gccgtcctgt accaccggca cgcggcgtcc acggccgtcc
     3361 ggctccagcg cgccgacggc gtggtgcgcc acatccgcat cgtggcggag ccggtgacgg
     3421 gtccggacgg cgcgctgctg gccgtcaggg gtgcctacca ggacgtgtcg gcgcagcact
     3481 ggacggaggt ggcgctcgcc gcgacccggg accggctcgc cgactccgag cagcgcgtgg
     3541 ccgagcggaa ccgcctcgcc ctccagctcc agcaggcgat catgccgccg acgtcggcgc
     3601 cggtggatct cgccgacctg cgggtcgcgg tgcgctaccg gccggcggag gaggggcacc
     3661 tcgtcggggg cgactggtac gacgccgtgc tgctgcccac gaagaaggtg ctgctcgtcg
     3721 tcggcgacgt ggcggggcac ggcatcgagg cggcgaccgg gatggtggtc ctgcgcaacg
     3781 ccctgcgcgg actggcggcg accggttcgg gtcccgcgca gctgctcggc tggctcaaca
     3841 cggtggcgca ccacctcacg gagcacgtga ccgccacggc cgtctgcggg gtgtacgacc
     3901 cggagacgcg ggtgctgcgc tgggcgaggg cgggacaccc gccgccggtg ctggtgcgtg
     3961 acggcgaggc gttcacgctg ccgctgccgc gcggtctgct gctgggtgcc ataccggacg
     4021 cggagtacga ggagcaccgg ctgccgatgg aactgggcga ccggctgttc atgtacaccg
     4081 acggtctgat cgagcggcgg gaccgttcgg tggagcactc gctccagcag ctgctgccca
     4141 tcgccgggca gagcacccgc gacctgggcg agcacctgga cctgctcctg acgcacagcc
     4201 ggtccgacac ggacgacgac acgtgtctga tcggcgtgca ggtcggctga gcgggccggc
     4261 tgagggccgt ggccgggcgg ccggggccgt tgcggagctc ggcgggctgg ggccgagcgg
     4321 gcctgggcgg ccctgccgag cgggtcgggg ctgggcggac tgcgggcgga cgggggctga
     4381 gcgggcccgc tgaggggccg ggtgagcgat gccgggtgga tccgggcgag cgggggctga
     4441 gcgggccccg gcggccgggg ccgagcgggc ctcggcagcc ttgccgggcg ggtcggggcc
     4501 cggcgaatcc gggcggtctc ccgagcggtc ggggccgcgc gggccaggac tgggtcactg
     4561 gttcgccggg caggtcggtc ccctccggcg tcccgacatc ccggcctccc cgggccccct
     4621 cctggcgtcc cggctccccc ggcgcctcag gaggtcgcca ggaggccctc ccgcaggcgc
     4681 cgcacggtgc gggcgagcag gcgcgacacg tgcatctgcg acaccccgag cacctcggcg
     4741 atctgcgcct gcgtccgctc ctcgacgaac cgcaggtgca ggatggtgcg gtcccgctcg
     4801 tcgagttccg cgacgagggg ggcgagggag tggaagtcct cgatgagttc gagggcgtgc
     4861 tcctcgacgc cgatgaagtc ggcgagcacg gcctcgccgt ccggtgagtc gccgcgcacg
     4921 gcggcgtcga gcgaggccga gctgtacccg gcggcggcga cctgggcctt gcggacctcg
     4981 tcctcggtca tgcccgtcag gtcggcgagt tcggagacct tcgggtcgcg gccgagccgg
     5041 gaggtgagtt cgtccgtcgc gcgcaccagt tcctgacgcg cctcctggag gcggcgcggg
     5101 acgtgcacgg cccacgaggt gtcccggaag aaccgcttga tctctccgag gatgcagggc
     5161 atggcgaagg tggtgaactc cacctcgcgg gacaggtcga accggtcgat cgccttgatg
     5221 aggccgatca tgcccacctg gacgatgtcg tccatgtcgc tgcccggccc gcggaagcgc
     5281 cgcgcggcga agcggacgag cgacatgttc atctcgatga gcgtgttgcg cacgtactgg
     5341 tggtcgtggg tgccctcctc cagcgtcgcc agccggtcga agaacgtcct ggagagttca
     5401 cgcgcgtcct ggggggagag ccgctgcggc tcgacgtccc cagggatgcg cccctcgcga
     5461 tccgccgccg tcgacgtccc cgccgcgatc accgtcatgt cccctccgat tctgccgtcg
     5521 tgcccgccgt gccggcgcgc gtgtgggtgg tcggggccgg gccgggcccg gcggccggtc
     5581 agagcgcgag gaccgggtcg ttcccgtgga cctcggcgag ccggcgtcgg accgcggcga
     5641 gcgcgtcctc gacgtcacgg gtgccggtcg agacgcacag cgtgtacgcg acgtcctcca
     5701 tgcggcgccg cacctcgggg ccgtcggcct gcgcgcgccg ggcctccaac gacgcgtact
     5761 cctctgccag cttgctcagc acggcggggt gggccatcaa cacggctcgt ctcctctcgc
     5821 tccggcgggc gtcctacgcc tcgcctggaa gcgctgctac ccccgacccc cgcgcccatg
     5881 ccggtgcggt gccccggttc gacgcaaaag cgcgggcctc ggccgaatcg tttcggtcgg
     5941 ggcccgtcgc tgagggggcg tcagtccgtg gacagcgcct ccagcaggtc gccgaccttc
     6001 ggctccggca gcgcccgcgc cacgtcggcc tgggcgacca tgccgaccag ttcgtggccg
     6061 tcgatgaccg gcaggcggcg caccttgtgg ctcgtcatgg tccgcaggat ctcgtccgcg
     6121 tcgtcgtccg cgccgatcgt cacgacctcg ccctgggcca gttcgccggc cttgcagctc
     6181 gccgggtcct tgccggcgcc gagcaccttc acgacgatgt cgcggtcggt cagcatgccc
     6241 ttgagcttgt cgtccgcgcc gcagatgggc agggcaccga ctccgaggtc cgtcatcttc
     6301 ctggcggcgt cgagcacgct ctcgttctcc ccgacacact cggcgccctc ggtcatgatc
     6361 tctcgtgccg tcgtcatggt ctggccttcc ctccttcgat gacctcccga ccgcgcgccg
     6421 tcccgtgggt cgcggcggcc ggtgttccga cggaacgacg ggtcccccgc catccggccc
     6481 gactaacccc gtttcccccg atccgcaacc ggagggcggc atgggcatgc atgtacgagt
     6541 aacgggcaca cgatcgtccc ccgagtgtgg aggacgccat gaccatgaca gagccgccgg
     6601 tcgaccgggg cacgagaact ccccctgcct gccgtacggg ggacgactcc gtcacccgcg
     6661 acgacgtcac ccccgacgac cggccggagt cggcccggga ccgggtgaac cgcaggtggc
     6721 aggagatcct gcaggagacc cgggtggccc agacgggcgt ccagatcctc ttcggcttcc
     6781 tgctgagcgt cgccttcacc cccgtcttcc gtgacctggg gacgttcgac cgggcggtct
     6841 acgtcgtgac ggtggtgacc ggggcgtccg ccaccgcggc cctcatagcc ccggtctccc
     6901 tgcaccggtt cctgtccggc cagcgcatga aggacgagct ggtcgggacc gcgcacaagc
     6961 tgatgatgtg cggcatggtg ctgctcgccc tgacgatcgg ctgcaccctg ctgctcatcc
     7021 tccacgtggt ggtcccgggc ctgctcgcgg agctcctggt gggcggggtg atgctgtggt
     7081 tcgcgctgtg ctggtacgcc ctgcccctgt ggctgcggca ccggtcgggc cgccgcgggg
     7141 acgacgaccc ggcggcacgc ggatgagcgg cggcgcgtac gggtcgcacg agggcgcgta
     7201 cgggccgggg tcgggcggcg ggcgccgcgc gggccggagc aggagtggga gccgacgatc
     7261 ggggcaggcg ggctggaccc cagcgccgag gaagggtgag tgacgtgcgg agtgtgggtg
     7321 tggaggagga gctgctcctg gtggacggcc gtaccgggga gccgcgtgcc ttgtccgcgg
     7381 cggtcctcgc ggcggcctcc cgggacccgc agggcaacga ggaggtcttc gagagcgagc
     7441 tgcagcgcca gcagctggag ttcgcgacga agccgcagac ggacatgcgg gatctggagg
     7501 aggagatccg acgctggcgg gcggaggccg cccggcacgc cgaaggggtc gacgcctcgg
     7561 tcgccgcgct ggcgacgtcc ccgctggagg tgagcccgac catcgggaac gacgagcgcc
     7621 accagtggct caaggagcac ttcggcctca cggcgcagga gcagctgacg tgcggctgtc
     7681 acgtccacgt gtcggtcgac tccgacgacg agggcgtcgc ggtcctggac cgcatccgcc
     7741 cctggctgcc cgccctgctc gccatgagcg ccaactcgcc gttctggcag ggcgaggaca
     7801 gcgggtacgc cagctaccgc aaccgcgtgt ggggccgctg gccctcggcc ggtcccgtgg
     7861 aggtgttcgg ctcggcggac cggtaccacg agcaggtcgc cgacatggtg gccagcggcg
     7921 ccctcaagga cgagggcatg gtgtacttcg acgcccgcct ctcccgctcg taccccaccg
     7981 tggagatccg ggtcgcggac gtctgcctcg acccgtccac cacggccctg atcgccacgc
     8041 tgatccgggg cctggtcgac acggcggccc gggagtggcg cgacggggtg ccgcccacgc
     8101 ggcacggcgt cgccctgctg cgcctggcgt cctggcgggc cgcccggtcc ggtctggagg
     8161 accagctgat ccaccccgtc acgatgcgcc ccgcgcccgc cgaggccgtg gtgcgggcgc
     8221 tcttcgacca cgtgcgcgac gcgctggagg agaacggcga cctcctcggc gcgcaggacg
     8281 ccctcgccgg actgctcgcc acgggcaacg gcgcccgcgt ccagcggacg ctgctgcacc
     8341 gcaccgggag cctgcaggag gtcgtggcgg agtgcgtgcg ccgcacgctc gcctgacgcc
     8401 ccgcaccgcg ccccccgcgg cgtgacggat cggccggtcg ccctacggcg accggccgat
     8461 ccgtgcgtac gggagacggc cgacctgcgg cggagcccgg tctaccgcga ccgctcccct
     8521 ttcgggcgac gggcgcggcg ctcccttgtg acggccaccc gacggtacgg acgctggttc
     8581 ccgggcgccc gtcgtcgggt gccccgcccg cgcgtggtcg ggtgccccgc cccggcgcgg
     8641 gcggcgtgcc ggccgcccgc ccgtcatcga ggaggtgccg tcttgacgcc ctgccgtatc
     8701 cccccggacc acgaccccga cgtcatcagg accgtccacc gggtcggcct caccctcggc
     8761 gtgtcggaca aggtcatgct ggccgcgttc gaagccggct gggtcgagtc gcacatgaac
     8821 aacctggact gcggcgacaa ggactcgctc ggcgtcttcc agcagcgccc cagccagggg
     8881 tggggcacgc ccgagcagat cagggacgtg ccctacgcgg ccgagcggtt cttccgcggc
     8941 gcgatgggcg tcgagcggcg gtcacccggc ctgtccgccg gccgcaccgc ccaggaggtg
     9001 cagcggtcgg cgcacccgga ccgctacgac gcggcggagg gcaaggcgag ggccctcctc
     9061 cgcgaggccg aggcggcggc cgcagccgcg cccccgcggg tcggggcggc cgggatcccc
     9121 gcgccgaccg agccggcacc accacgggcc gtacccgcgc aggccatccc tccgtcggcc
     9181 gggcaggcgc ggcgggccgg gcaggcgcgc ggcaggtcgg ccgacggggc cgcggcgggg
     9241 cagtgacccg gcgcgcaccg gcccggccgc cttccggcac ctgaccgccc ggaacaccac
     9301 cggcggcgtc cggtgtacgg cggccccgcc gtacaccggt cacgtccgat cagggcatgc
     9361 cggtgcgggg tcccggtgcg gggtcccggc gaccgcgacc gccgcgcggg gacgcgcgaa
     9421 gcggccccct cgcgtcgacg gcgacccggg tggagccggt cggtgcccga gaatcgaccg
     9481 gctcacttgg gtggggcggt tgcccgtgga cggcgcgcgg aggggacgcg gtgcgccggg
     9541 cgccgctcgt cgtctccagc cgggcggacg gggctcaggg agggcgcggg ccatcccggt
     9601 gcaggtcgaa tcgtttcagc agggaagcgg tggccacact cggtcgatca caaccgagtc
     9661 gagtcccaag tggccaccga aggaagaccg attggcccga tagtccgact aggccttgca
     9721 gggttgtgat tccgcctgac cgtgcggata gctggtggtc ggggcgacca ccccggtcgt
     9781 ggagcctgat gggcccacca ccgggtcggc ccccacggca cagccgccac cccccgcccg
     9841 ggtgggtggc gaaccgaccg gaggaatagt catgaagaag gcgtacgagg ctccgaccct
     9901 ggcccggctg ggcagcttcc gcaagacgac ggggctcctg cagcgctccg gcaacgaccg
     9961 gctgatcttc agcaagaact gacgctcccg acctgacgtc atgacggaac tgcacgaaag
    10021 tgcggggacg ggccacggcg gcgcgcactt cgcggtcttc accgaccgcg cggacgcggc
    10081 cgccgcggcc cgctccttcc gacgccccgg gacccgcgtc ctggcccacg cctccgggag
    10141 gccctggctg atcggccggt gggacgacga cgaactcgtc accgcccgcg ccggctccgc
    10201 cgcgctcgcc ctggtcggca cctgccccgt cgacgccgcc gaggtgcgcc gggtcgccgg
    10261 ccgcctgcgc gacctggccg acctggacgc ctgggtacgg tccctgcccg gcagcttcca
    10321 cctggtcgcc gcgctcgacg gccggaccag ggtgcagggc accgcgtccg gcctccgcct
    10381 cgtccaccac gccgacctcg gcggggtgac ggtcgccgcc acccgcgccg actggctcgc
    10441 cgccgccctg ggccgcgcgc ccgaccgcgc gcagctggcc gtacggctgc tgtggccggt
    10501 gccgcaccca ctgtccgagg cctccctctg ggagggggtc cacgcggtcc cgccggacga
    10561 ggcgctcgtc gtcgcggcgg acgggcgcgg ggtgcgccgc tcgcggtggt ggatgccccc
    10621 ggagccggtc caggccctgg cggagggggc cccgcgggta cgacaggccc tcgccgaggc
    10681 cgtggacgcc cgcacccggg gcggcggcgt cgtcagctgc gacctgtcgg gcgggctgga
    10741 ctccacctcc gtctgcttcc tcgccgaccg gtcaccggcc cgtgtggtgg cgagcacctg
    10801 gccgggccgc gaccctgccg acaccgacct ggagtgggcc cgccgggccg cccgcgccct
    10861 gcccgacgtg gagcacgtcg tgtgggacgc cgacgcctcg ccactcgtct acgacgacct
    10921 gctcggcatc gacgatctcc tggacgagcc gacgatcggg gtcatggacc ggtcgcgcgt
    10981 cctgcaccac ctgcccggca tggcgcgccg gggcagccgc atccacctga cgggcatcgg
    11041 cggggaccac gtcgcctggt gctcggaggc gtactatcac cggctcgccc ggacacggcc
    11101 gttgttcgcc ctgcggcagc tgcgcggctt ccgcgccctg tggcagtggc cgctcggcgg
    11161 gacactgcgg gcgctggccg acaaccggcc gtacggcagg tggctccgcg actgcacggt
    11221 cgacctgcgc ggggcgcggc ccgccaccgt caccaccagc ctcggctggg gcatgcctcc
    11281 ccgcctgttc gactgggtca cgtcggacgc cgcggagctg gcggggcggg cactgcgcga
    11341 cgcggccgcc ggggcccggc ccctgcaccc ggaccgcggt ctccacaccg acctggagca
    11401 gatccgcggc tgcacccgca tcatccgcca gtgggaccac atggccgccc ggacggggct
    11461 gcccatggcg tcccccttcc tggacgaccg ggtcatcgag gcctgcctcg cggtgcgccc
    11521 cgccgagcgg gtctccccgt ggcggtacaa gcccctgctc accgcggcga tgcgcgggat
    11581 cgtgccggag gagtgcctgc ggcgcaccga caaggccgcc gcctccatgg acgcggcgga
    11641 cgggctgcgg gagcaccgcg ccgacctcat ggccctgtgg gaggactccc ggctggagcg
    11701 gctggggctc gtcgacggcg tggccctgcg ccgtctcgcc cagcgtccct ccacgccgga
    11761 gctgcacgac ggggtcctct acccgaccat cgcggcggag gtgtggctcc gcggcctcga
    11821 accggcccgc gacggcacgg cccccgcccg cccctgaccc cttcccaccc ccggccggct
    11881 ctcccccggc cggctccccc cgcatctccc cctccgatcg gccccgccgg cccagcccgc
    11941 cccggccacc cccggcgccc ggcccttccg gcgccgcccg gcgcccacca ccagaaagga
    12001 ccctcgcatg gcactgcggt tctcggcgga cgtgtccacc gcgaagacgg actacggcac
    12061 cgtcctcctg gacgaacgcg gcggtgagta ctgggagctg aacccgagcg cgaccctggt
    12121 ggtcggcgtc ctgatgtcgg gtggtgacga ggacgccgcc gcggcggcgc tggtcgcgga
    12181 gttcgacgtc gatccgcagg gcgccgcgcg ggacgtcgcg gccctcgtcg gggagctgcg
    12241 ggccgcgggg ctggccgcat gacgacaccg tccgcgctcg aacggcccga gggcgtaccg
    12301 ttcgcccggc ggtgcgccgc ccggctggtg ctgctgcccg ccctcgccct ctccctcctg
    12361 ccgccccgcc ggatccgcgg cgtcctcgac ctgttgcggc ggggcgccgc gccggcgagc
    12421 gcggcgcagg cggcggacgc ccgtgacgcg gtgtgcgcgg tgagcctgcg ctgcgccggc
    12481 cccaagggct gcctgccgcg gtccctcggc gcggcgctgc tctgccggct cggcggcacg
    12541 tggcccacgt ggtgcaccgg tgtgcgcgtc gtccccccgt tcacggccca cgcctgggtc
    12601 gaggcggagg ggcgtcccgt gggcgaggac gcgccggacg actacttcac gcgtctgatg
    12661 gcgatcggtc ccgccccccg gccgccccgc cggtgagcgc cgcgcacggc cccgcgaccc
    12721 cgacggcacc acaggggcga cggcgacggc cgcgggggcg acgtccacgt ggacgtccat
    12781 cgccaccctg tacggcctca cggtcgggca ccgccgcgcc atcgccctgg ctgtcgtcct
    12841 cagcctcgcg gcggcggccc tcggactcac ccagccgctg ctcgcccggg aggccgtcga
    12901 acggggtgcc ggggggcggg cgttcgggtc ggtcctgctg ctcctggccg ccgtgttcgc
    12961 cgcggaggcc tcgacgggcg ccgtcggccg ctacctcctg gagcgcacgg gcgagggcgt
    13021 ggtccgccgg ctgcgccacg ggctggtcga ccggttcctg cggctggagg tgcgcgagta
    13081 ccaccggcac cgcgccggtg acctgacctc ccgcgtcacc gccgacacga ccgtcctgcg
    13141 cgaggtcgtc tcgcaggcgc tcgtcgacct ggtcacgggg gcactggtcg cggccggggc
    13201 catcgcgctc atggcgtggc tcgacccgct gctgctcctc gtggcgttga cggtggtggt
    13261 ggcctcgatg ctggtcgcct cgatgctgaa ggggatccgc gcggcgtcgg cgcacacaca
    13321 ggactcggtc ggcgcggtcg ccgcggaact ggaacgggcc ctgggtgccc tgcccctggt
    13381 gcgggtgcac cgtgccgagg agcgcgaggc ggccgccatc gggactccag cgcggtgccg
    13441 gcgcccacgc gcgggtacgg caggccctgg gcctgccggc ggagccaccg gacccccccg
    13501 cccaggtcct cgacgccgcc cctgcccccg ccacggccac ggcggccact cacggtcccg
    13561 gtgccacgcc cgccacggcg tccgccgccc cccgcgtccc cgcctccgcc cggcgggcgg
    13621 acgctaccgg tgcggcggca cccgtactcg ccctgcacga cgtgcacttc gcgtacacgt
    13681 cgggccggcc cgtcctgcgc ggggtgtcgc tgacggtgcc gtcccggcgc caggtggccc
    13741 tggtcggtac ctcgggtgcg ggcaagagca ccctgttcgc cctggtggcg cggttctatg
    13801 agccggacgc ggggaccctg tcgttcgacg gtgtgcccgc ggcggagctg ggccgatccg
    13861 actgccgcgc gcgcatcgcg gtcgtcgacc agaacacccg cgtggtccac ggcaccctgt
    13921 gggacaacat cacgtacggc gcccccgacg ccggcgaggc cgaggtccgc cgcgtcgtcg
    13981 acctggcccg gctcggtgcc gtcgtcgagc ggctccccgg cggtctgcgc ggagcggtcg
    14041 gcgagcgcgg cgcgaccctg tcggggggcg agcgccaacg cgtcgccctc gcgcgggcgc
    14101 tgctcacgcg cccctcctgc tcttgccgcg caggtgctcc gaccggcggt ggtggcgggc
    14161 gcctccctcg gtacccccac cggccggggc ggaacaggcg acttccgttc attgcgcccc
    14221 taaaggggcg ccatcgcgta gcgaaacagg gcgaaacagg cgctttttcc tcccattcga
    14281 gctgggtgtc cgctcaggtg ggcaccgctt gaaaggtcaa agtgctgtcg ggttagcata
    14341 tgagcaccgc ctagctcgaa agatgaacct gtgactgtca atgaggactc gttcaccagc
    14401 tggaagaacc gcgaggagat cgcggagtcg atgatcccga tcatcgggaa gctgcacagg
    14461 gagcgggacg tcacggtcct gctccacagc cgctccctgg tgaacaagtc ggtggtcagc
    14521 atcctcaaga cccaccggtt cgcccggcag atcgccggtg aggagctctc ggtcaccgag
    14581 acgatgccct tcctgcgggc cctcaccacg ctcgacctcg gcccgtccca gatcgacatc
    14641 ggcatgctcg cggcgaccta ccggaccgac gaccgcggcc tgtccgtcga ggagttcacc
    14701 gccgaggccg tggccggcgc gaccggcgcc gacaagatcg agcgcagcga gccccgcgac
    14761 gtggtcctct acggcttcgg ccgcatcggc cgcctcgtcg cgcgcctcct catcgagaag
    14821 gccggctccg gcaacggcct gcgcctgcgc gccatcgtgg tccgccgggg cggcgagcag
    14881 gacatcgtca agcgcgcctc gctgctgcgg cgcgactcga tccacggcca gttccagggc
    14941 acgatcaccg tcgacgaggc gaacagcacg atcgtcgcca acggcaacgc catcaaggtg
    15001 atctacgcgg gcgacccgtc ggagatcgac tacacggcgt acggcatcaa gaacgccatc
    15061 ctcatcgaca acaccggcaa gtggcgcgac cgcgagggcc tgtcgcagca cctgcgaccc
    15121 ggcatcgaca aggtcgtcct gaccgccccg ggcaagggcg acgtcccgaa catcgtccac
    15181 ggcgtcaacc acgacaccat caagccggac gagcaggtcc tgtcctgcgc ctcctgcacc
    15241 accaacgcga tcgtcccgcc gctcaaggcg atggcggacg agtacggcgt cctgcgcggg
    15301 cacgtggaga ccgtccactc gttcaccaac gaccagaacc tgctggacaa ctaccacaag
    15361 gcggaccgcc ggggccgctc cgcgccgctc aacatggtca tcaccgagac cggcgccgcc
    15421 tccgccgtcg ccaaggcgct gccggagctg aaggcgccga tcaccggcag ctccatccgc
    15481 gtcccggtgc cggacgtgtc gatcgccatc ctcagcctcc ggctgggccg cgagaccacc
    15541 cgcgaggagg tcctcgacta cctccgcaac gtctcgctga cgtcgccgct gaagcgtcag
    15601 atcgacttca ccaccgcccc cgacgcggtg tcgagcgact tcatcggatc gcgccacgcc
    15661 tcgatcgtcg acgccggcgc caccaaggtc gacggcgaca acgccatcct ctacctgtgg
    15721 tacgacaacg agttcggcta ctcgtgccag gtgatccgcg tcgtgcagca cgtctccggg
    15781 gtggagtacc cgacgtaccc ggcgcccgca gtctgacacg gcgtcaccac ctcccggccc
    15841 gcgtcgcgcg gccggggcgg cggtggggcg gcggccggtc gacccggctc cccccactcc
    15901 cccgccccgc ccgctcggcg cgggccgtcg gcgtgccgac ccgagcggac ggcccgagcc
    15961 ggcgggggcc cgagcgcggc cttccggacc cgacggcccg agcgcggcgg ggcctgcgtg
    16021 acggcggccg cgtgcggcgg cggccccggc acggcggctc cgagcggcgc tgcccgtgcc
    16081 gggcgggtgc cgggccgggc ggggcgggtg ccgggccggg cggggcgggt gccgggccga
    16141 gcggcggacc tgccgcgccg gagttacctt ggcagtgcga ccgtgcgcac gccccgcgcc
    16201 cgcccggccc cacgggcccc tctcgtggac gctcacccga catgccctgc tccggaaggg
    16261 gcgaacgcca tgcgtgtcat cgcctattac ctgcacgagg gggaggccgc cgaggccgtg
    16321 cgcgtgctcc gcaacacctc ggtcaccagc ggtttcgtcg tcggcgacgc cgacgcggac
    16381 gacctgccgc ggctcgccgc ggcaggcctg ctggtcgacc cgctcgaccc gggccccgct
    16441 gccgtaccgc cctcccccgc ccgcgccacg ctccgcgccc acgacaccgg aaccggggcc
    16501 ggggccgacg cgcgggaggg cagtggaccc gaaccgctcc ccccggagcc cggggtgtcc
    16561 gcgcagtggg tgctgcacct gggcgaaccg ctgctggagg agtaccgcgc cgggatcgtc
    16621 agccagggcg tggtcctgct gcgcgccctg cccggcggcg cctacctcgt cacggccacc
    16681 cccgagcagg ccgaggacgt cctgaacctg ccctacgtca gatccgtacg gcaccacgac
    16741 cccgacgcgg cggccccgct gcggttgtcg gccggggagc tcaccgaggt ggagacggaa
    16801 ggtcacggca cgacggccct gcgcacctgg gacctggtga cggccgacgc cgacgcccgc
    16861 gcgggcgtac gcgcctggct gctggcgcgc gccgacgcgc acggaccgga gatcgtcgcc
    16921 gagggcgggc gccgcctgcg cgtccggctc cccgccggat cgccgctgga ggaggaggtc
    16981 gcccgggtcc cgggagtcct ggccgtgacc gagtacgtgg agccgaagct cttcaacgac
    17041 gtcgcccgcg cactgctcgg cgtgacgccg gcggaggcgg cgggcggcct gccgctgacg
    17101 ggccggggcg aggtcgtcgc cgtggccgac accggcttcg acaccacgca ccccgacttc
    17161 gacggccgcg tggtcggcac ggccgccctg ggccgccccg gcgactcctc cgacccccac
    17221 ggacacggca cgcacgtggc ggggtccgtc ctcggcgacg gcagcgcctc ccagggcgcc
    17281 ttccggggcg tcgcgccgga ggcgaagctg tacttccagt cggtgcagga ccggcacggc
    17341 ggcctcggcg gtctgccggc ctcgctggag gacctgttcg agcccgccta ccaggccggg
    17401 gcccgcgtcc acaacgacag ttggggcgcc gccaccgagg ccgcgtacac cgccaactcc
    17461 gacgacgtcg acgcctacgt gcggcggcgg cccgacatgc tcgtcgtgat cgccgcgggg
    17521 aacgagggca cggcggcggc ccgcctccac gcgcaggagg ggttcgtcga ctggctgtcg
    17581 ctgggctcgc ccgggtcgag caagaacgcc ctgacggtcg gcgccgcgcg caccagccgc
    17641 gccgacgggc ccggtgggga cctcacctgg ggcgaatggg accggggcac gcccttcccc
    17701 gacgacccga tcgccggcga gcgggtctcg ggcgaccccg aggcgctggc cgcgttcagc
    17761 agccgcggcc cgtgcgacga ctggcgcgtg aagcccgacg tggtggcgcc cggcacggac
    17821 atcctgtcga cgcgcgccgc cggcgccccc cggcagagct tctggggcct ccacgacaac
    17881 ccccggtacg ccttcatggg cggcaccagc atggccaccc cgctcgtcgc gggctgcgcc
    17941 gcgctggtgc gcgagtacta cgtgcgggag cggggcacca gccccagcgc cgccctggtg
    18001 aaggccacgc tgatcaacgg cgcccggcgg ctcaccgcgc cggacgccac ggccccggac
    18061 ccccacttcc accaggggtt cggcgcggtg cacctgccgt ccaccctgcc gaacccggcc
    18121 gtcccggacc tggtgctcga cttcgccgac acctggcaga cccccgcacg gcagctcgcc
    18181 cggaccggtg acgtcagccg cttcacggtg gaggtggcgg ccggcgcacc cctgcggctc
    18241 tgcctggcgt acacggacct gccgggccgg tccctgcaga acgacctcag cgtgctggtg
    18301 gagacgcccg acggcgtccg gcacgccggg aacgacaccc tgcccaaccg gcttctgcag
    18361 acggacagca cgaacaacgt cgaggtcgtc cgcctcccgg acgccccgca gggccggtac
    18421 ctgatccagg tgttcgcccg caatctgctg gagggcccgc aggacttcgc cctggtggtg
    18481 acgggcaggc tgaccggccc cctgcggcgc acgaccggct gaaccgcgtc ctggacggcg
    18541 agcgggtggc cggggaccgg gcgcgatcgc ggcgcgcccg tgcgccccgc caacgccgtc
    18601 ccgcccgtcc cgcccgtccc ggggcaccgg ccacggggca ccggctacag ggtgcgggcc
    18661 acggggtgcg ggcgctcggg gcacccggtc ccggggcgga agcgacggcg ccgggccccc
    18721 gggggcaggg gccggagccc ccgccgtttc agcccgcctc gtcgggtggt tccggtgccg
    18781 ccgccgggtc ctcccagggc gggggcgtgc ggccgtcggt ccaggcggcg agggcctccc
    18841 cgtccacgca gacgatgccg atcgtctcgg cgtactcgac ggccggcgcc gtgaacgtgc
    18901 tggtcgtcac gacgaccgcg acctccgccc cgtggacggc gaagcaggtg ccaccgaagc
    18961 gctggaggtc ctgcgagccg acgggattgt cggcggcgta ctgcttgcac tggacgatca
    19021 gccggcggcc gtcgggtgcc gtcgccacga cgtcggcacc caggtcgccc gggccgccgg
    19081 acacctccgt ccgcgtgcag ccgtcccgta cgcacagcgc ggccaccgtg tgctcgaagc
    19141 cgtacgcgtc gacctcctcg tggtcgacgc tgtcgccgtc cagccggggt accggcgggg
    19201 ccggcgcggc gccttcgacg gggagcaccg ccgtgacctc gtcggggccc gggggcgggg
    19261 cctgcgccgg gatcgccgcc cggccggggg cgcggcgcgt ggcggcccgg cccgccacga
    19321 cggccgcgag gaccaccatg acgagcagca ggacggggcc gaacgccccg tcgggcacgt
    19381 gccacacggt gcgcaccagc aacgccagcc cgccgacggc caccccgacc agccccaggg
    19441 cgagcaccac gtcccgccag ccggcccgcc gtgcccccgg caccctcggc gccctccgcg
    19501 ctctcggcac cctctgggct ctcggcgccc tcggcgccct cgtcgtcctc tgcggtacgg
    19561 tcacgcggca ccccctccct gacaccccgt ctggccccgc cgcccggcgc caaaccccgc
    19621 ggcccgaacc ggctcccgcc cggaccggct ccggcccggc ggcccgcggg caccgacacg
    19681 cgtgcgccgg gccgccgtcg cgaggacggc ggcccggcga ggagcgcggg acgggtcagc
    19741 agtgaccgac ggccgtctgg ttggccacga gcgacgagtg gacgtagccg gtgcccttgt
    19801 ggctgctcac ccggaaccag cggttcgacg cgtagttcgc gctgggcggg tagacccact
    19861 ggctgtcgag ccagcactgc atggacacgc cggtgccgtt ggtgaggtag ccgagggagc
    19921 cgcaggaggt ggaggcgcag gtgcggaggt tggcgccgcc gctgttggag gagatgtggc
    19981 tgccggccgc ttcggccgta cccgcgccga cggtgagggc tgtcagggcg acggccgccg
    20041 ccgtggccag tccggcacgg gtccgcagga gggtgggtgt ccgcatggtg gtgtccttcc
    20101 gatcggtgtg cgccccggtg gcgccccatc aggaagtcac ccgggtgggg cactcgggaa
    20161 ggggagaccc gcaggtcgga cgggtccgta cggcggtccg tacaactccg tacggccgag
    20221 cggcgggccg gcgcggcggg actgggcgct ggtgcgcggc gagcgggtgt cccgggccac
    20281 cctggtccgg ttcgtccgca gcgcggcgga gctgcgccga ctgctggagg gggcggggtt
    20341 cgcccgggtc gaacttcttc ggcggcttcg acggccggcc ctacgaccag gacgccgagc
    20401 ggctcgtggt gcggtgcggg caggctgacg gatcggcggg gcgcacggtt ccggccgtgc
    20461 gccctttcgt ccctgacgtg gcgaatcgta ggatcatctg gtcatcaccg cgacgggaga
    20521 caggaagccg gtgcgattcc ggcacggtcc cgccactgtg accggggagt ggaccccacc
    20581 ggaaggccac tgcgcacgcg cgggaaggcc gggggaacgt cgatccggga gtcaggacac
    20641 tggcctgtcg cgggcccgat ccgaggagcg cggactccgc aggaggcttc acgtgtacga
    20701 cggctcgtcc cgtcccccct tccccacccc tgcccgggcg cgcgggcgcg ccctgggcgc
    20761 ggcggccctg gccgccgtcc tctccgcgac cctgctgtcc ggctgcggca cctcgcgcgg
    20821 cgcggacgac ggccgcccgt ccgcggcggc gcggcccgcg aagggcttcc ccgtcaccgt
    20881 cgacaactgc ggcacgcgca cgacgtacga caggccgccg gagcgggtgg tcaccatcca
    20941 ccagcacccg gccgaactgc tgctggccct cggtctgaag gaccgcatgg tgggcaccgc
    21001 cttccccgac tcggcggtcc tgccccagta ccggaaggac ttcgcggccg tcccccgact
    21061 cgcggagaag gagccgtcct tcgagacggt cctcgacgcc gaaccggacc tcgtgtacgg
    21121 cggctacgcc agcgcgttcg acgacaaggc gggccgctcc cgggcggcgt tccgggacgc
    21181 ggggatcgac acgtacctga accgcgagta ctgcggcggc aggagcgtgt ccatgcggga
    21241 cacgtacgag gagatccgta ccctcggctc gatcttcggc gtgccggagc gggccgacgc
    21301 gctcgtcgcc gacctccgct cgcgcatcga cgaggcgacg cgggcggtga agggcgcccc
    21361 gcaggtcccg gtgttcgtct acgacagcgg cgacaaggcg gcgttcacgg ccggcggcaa
    21421 ggggctcggc accgagatca tccggctggc cggcggccgg aacgtcttcg cggacctcga
    21481 cgaggtcttc ggcgacgtgt cgtgggagca ggtcgtcgcg cgcaagcccg aggtcatcgc
    21541 gatctacgac tacgcgggcg cgggcggcgt cgagcagaag aagcggttcc tgctggcgca
    21601 accggcgctc gccgacgtgc ccgcgatcag gaacaagcgg ttcgtggtgc tgccgctgac
    21661 ggcgacgctc gtcggcgtcc gcccgccgta cgcggtcggg gacctggcca aggccctgca
    21721 ccccgagcgg ttccggtgac ggccaccgcc cccgccgccc ccgccgaccg caccgacccc
    21781 ggcccccggg gccgggcggg cggcggcggg ccccgccgtg cctcgttcgc cttcaccctc
    21841 gtcctcctcg gcgtcctgct ggtggtctcc gcgacggcgg gcatggccat cggctcggtg
    21901 cgcgtgccgc cgggcgaggt gtggggcatc gtgacgcacg cgctgggcgc ggactggtcc
    21961 gagccgacgt ggtcgcgggc gcgcgagacg atcgtgctcg acgtgcgggc gccacgcgta
    22021 ctgctcggcg tggtcacggg cgcgggtctc gcggtggtgg gcgccgccct gcaggcactg
    22081 gtgcgcaacc cgctcgccga gccgtacctg ctgggcgtgt cgtccggggc ggcgctcggc
    22141 gccgtcagcg tcatcgtcct cggcctcggc gtcttcgggg cgctgtccct gtcggtcgcc
    22201 gccttcgccg gcgccctgct cgccctgctc gtcgtgtacg ccaccgcccg cgcgggcggg
    22261 cggatcacct ccgtgcggct ggtgctgtcc ggcgtggccg tcgccgcggt cctcacggcg
    22321 gtcgtggacc tgctgctgct cacctccggc accggcgacc aggcccgcgc ggtcctcgcc
    22381 tggacgctcg gcgggctcgg cggcgtccgg tgggccggcc tgtggctgcc cgcggcggcg
    22441 ctgctgctgg ggatcggcgt gctgctggtc caggcgcggt cgctgaacct gctgctgtcg
    22501 ggcgaggagg ccgccgcgac gatgggcctg gacgtggccc ggttccgggc ccggatgttc
    22561 gtgctgctct ccctggtgac gggggtcatg gtggcggcga ccggaccgat cggcttcgtc
    22621 gggctgatgc tgccgcacat ggtgcgggtc ctcgtcggcg gcgaccaccg ccgggtcctg
    22681 ccgacggccg cgctgg
//
