LOCUS       NZ_CP102332            21116 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Streptomyces changanensis strain HL-66 chromosome, complete genome.
ACCESSION   NZ_CP102332
VERSION     NZ_CP102332.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces changanensis
  ORGANISM  Streptomyces changanensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6817869)
  AUTHORS   Wu,H. and Han,L.
  TITLE     Streptomyces changanensis sp. nov., an actinomycete isolated from
            soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6817869)
  AUTHORS   Wu,H. and Han,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2022) College of Forestry (Academy of Forestry),
            Northwest A&F University, Northwest A&F University, Yangling,
            Shaanxi 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.9; Pilon v. 1.24
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 187.45x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024600715.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 19:18:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,071
            CDSs (total)                      :: 5,982
            Genes (coding)                    :: 5,812
            CDSs (with protein)               :: 5,812
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 170
            CDSs (without protein)            :: 170
            Pseudo Genes (ambiguous residues) :: 0 of 170
            Pseudo Genes (frameshifted)       :: 70 of 170
            Pseudo Genes (incomplete)         :: 131 of 170
            Pseudo Genes (internal stop)      :: 9 of 170
            Pseudo Genes (multiple problems)  :: 37 of 170
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:13:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 456623
            Orig. end                         :: 477739
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102332.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21116
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21116
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21116
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11116](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11116)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            294..752
                     /locus_tag="NRO40_RS01985"
                     /old_locus_tag="NRO40_01985"
     CDS             294..752
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017241869.1"
                     /locus_tag="NRO40_RS01985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01985"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_257375315.1"
                     /transl_table=11
                     /translation="MSSTAPRINALPAPHRERLLALAEEVSFEPGERVFDEHRPADRFW
                     VVRTGAVNLDSRVPGSRRPAVIEMLGHGELVGLSWLFPPYEWELGAEAMSLVRAYEFDA
                     AVVRTLCEAEPPFGLALTQWVGQVLSHRLQATRERLLDMYAPHGSGVL"
     gene            879..1514
                     /locus_tag="NRO40_RS01990"
                     /old_locus_tag="NRO40_01990"
     CDS             879..1514
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237825.1"
                     /locus_tag="NRO40_RS01990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01990"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_058942817.1"
                     /transl_table=11
                     /translation="MRHRSVADLMTPEVVAVQRGTSFKEIARLLDEFGITAVPVVDGDG
                     RPVGVVSEADLLHRHTSGEQGPNTNTAEGLMSSPAVVARPHWSAVEAARVMERRRIKRL
                     PVVDGTGRIIGVLSRRDLLQLFLRRDRAIQEEILEDVVTRTMGLAPSAVTVDVNDGTVT
                     LSGMLERRSLVPILVRLCETVDGVVDVDDRLAYETDDTGALASGDMTG"
     gene            complement(1889..2191)
                     /locus_tag="NRO40_RS01995"
                     /old_locus_tag="NRO40_01995"
     CDS             complement(1889..2191)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031554.1"
                     /locus_tag="NRO40_RS01995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01995"
                     /product="DUF1876 domain-containing protein"
                     /protein_id="WP_058942816.1"
                     /transl_table=11
                     /translation="MARTLEWKINMELVEEGDTTEARAVLDTGKATVTGRGSARRNPED
                     ADVPLIGDELAASRAMGDLSRQLMRLAYKDIGEAGAGLSGEVEEDAPYGWSTPVS"
     gene            2449..3342
                     /locus_tag="NRO40_RS02000"
                     /old_locus_tag="NRO40_02000"
     CDS             2449..3342
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010474933.1"
                     /locus_tag="NRO40_RS02000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02000"
                     /product="universal stress protein"
                     /protein_id="WP_058942815.1"
                     /transl_table=11
                     /translation="MAQAPAHRAVAVGVDGSPESLAAAEWAAREAALRGLPLRLVQAWL
                     RQPVDGAPERDGAAEELRARHLLEEVAAEVRTRHPGLEVTSALLPAPPVPALLTAGNAA
                     EMLVIGSRGHGALLGFLLGSSGQQVIAEADRPVVAVRSPREDGPGTGADGGEVVVGQQG
                     DARESAAVLGFAFAAAAARGVGVRAVRAWSLPSVYAYTPGALRPVDEAGGLVPYEEKAL
                     AEALAPWRERYPGVPVREHVELGSAGQVLLSVVTGAGLVVVGRRVRRAPVGTRIGSVAH
                     AVLHHAPGPVAVVPHA"
     gene            3475..4623
                     /locus_tag="NRO40_RS02005"
                     /old_locus_tag="NRO40_02005"
     CDS             3475..4623
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PPDK_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008736757.1"
                     /locus_tag="NRO40_RS02005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02005"
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="WP_079047149.1"
                     /sec_met_domain="PPDK_N (E-value: 3.5e-16, bitscore: 57.8,
                     seeds: 105, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRYVYDVAEEPGDGRDGSGPPGGPGVDPVGLLGEKGADLTGLLR
                     LGLPVPAGFTVTSEACRVFLATGAPPPGLDAELAAHLARLERAAGRRLGRVDDPLLLSV
                     RPGARVAVPGLMPTVLDVGLNDHAVLGLAGTPARERFAWDSYRRLVRAFGTAVMGVDPA
                     LFDGVLHRIEDQHHVADDSRLDACDLIRIVETYKDVVRERTGEDFPQDPVEQLHRAVRA
                     AFASWAGEPARLHRRRAGLPDEPGVAVTVQTMVFGNRDAASGSGVALTRDPVAGGPGVY
                     GGYLPGAQGEDVASGTRDPLPLAEFARLDPDAYAALCGHLRRLEEHHRDVCGVAFTVER
                     GRLWTLRSFVGEPAVRAATAGAAARPAADGAAPGRTKDDRPD"
     gene            complement(4694..4972)
                     /locus_tag="NRO40_RS02010"
                     /old_locus_tag="NRO40_02010"
     CDS             complement(4694..4972)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS02010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NRO40_02010"
                     /product="hypothetical protein"
                     /protein_id="WP_058942814.1"
                     /transl_table=11
                     /translation="MSGVSDEEIVGAVRAIAELEERREALAERVGELRRAVTPEDLAER
                     DRFGTEMAVVTDLILLECVETLDRLGLTTAAQAVRRVLDEEGPAGQG"
     gene            complement(5027..6409)
                     /locus_tag="NRO40_RS02015"
                     /old_locus_tag="NRO40_02015"
     CDS             complement(5027..6409)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010986516.1"
                     /locus_tag="NRO40_RS02015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02015"
                     /product="cytochrome P450"
                     /protein_id="WP_058942813.1"
                     /sec_met_domain="p450 (E-value: 1.4e-83, bitscore: 279.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTITSRRVPGPSGLPLVGSLLDLKRDLLGTLLAAHRAHGDVVRI
                     TAGPPGLRSELYAVFSAEGAQQVLATSSANFRKDNVFYQEVRLSLGNGLLTSQDDEYLR
                     QRRLVQPLFTPRRVDRYADALTAEATALTRAWRDAPGATVDLADETNELTLRSVARVLF
                     GTDVESAVDVIARCFPVINDYVLGRSYAPVTLPREWPTPGNRRAAAAVAELYAECDRII
                     ARRRADGAPAQEDLLTLLTQAGSEDGDRLDPSEVRDQVLIFLLAGHETTASSLSFALHL
                     LARHPREQRLAREEVHRVLGGRAPRAADLTALPYLGRVVKEALRLYPAGPIVSRRAVTA
                     TPVGDHVIPAGADVFVAPWVTHRHTRHWPDPERFDPGRFTPEQEKNRHRYAWYPFGGGP
                     RACIGQHFSMLMSALALAVVLQEYELEAEEHDVPVDTGLTLHSTVPLRCRVRPSSHSRP
                     RT"
     misc_feature    6619..6635
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.72"
                     /tool="antismash"
     misc_feature    complement(6620..6635)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 23.65"
                     /tool="antismash"
     gene            6678..6959
                     /locus_tag="NRO40_RS02020"
                     /old_locus_tag="NRO40_02020"
     CDS             6678..6959
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965298.1"
                     /locus_tag="NRO40_RS02020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02020"
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="WP_058942812.1"
                     /transl_table=11
                     /translation="MELELTGAELKSVLNRLRRAQGQISGVIRMLEEGRDCEEVVTQLA
                     AAARALDRAGFAIIATGLRQCMTGDGGGTAGDREEARTRLEKLFLSLA"
     gene            complement(7001..7822)
                     /locus_tag="NRO40_RS02025"
                     /old_locus_tag="NRO40_02025"
     CDS             complement(7001..7822)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018845517.1"
                     /locus_tag="NRO40_RS02025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02025"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_058942811.1"
                     /transl_table=11
                     /translation="MTVLVLALTAGAVVGLALGALGGGGGVLAAPALIYLLGFGPVEAT
                     TAGLVVVAVTSATALYGHARDGRVRWTAGALFAAAGAVPAVLTASLADGVPRPVLTLAF
                     AAVAALAALRMLRPAADPDDDARDPAEPPAAEPPARDGPTPGAPRPRPLRAAGAGAGVG
                     ALTGFLGVGGGFLAVPALVGMVGLRMRAAVGTSLLVITANALTALVARAGTAAPVDWAV
                     VAPFTGAAVLAAWDGRRLAARVPATALRRIFGSALLAVAALMAVDGTARLL"
     gene            complement(7819..8175)
                     /locus_tag="NRO40_RS30500"
     CDS             complement(7819..8175)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012790.5"
                     /locus_tag="NRO40_RS30500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_306674896.1"
                     /transl_table=11
                     /translation="MVRPLCERVTARQAHHRTAAAGGAVLLDVREEPEWRAGHAPGAVH
                     APLSALRAGAPVPAAALDRPLVVICRSGQRSQHAAALLTRRGRRAVDVEGGMHAWAGAG
                     LPVVDAGGNRGSIA"
     gene            complement(<8173..9540)
                     /locus_tag="NRO40_RS02030"
                     /old_locus_tag="NRO40_02030"
                     /pseudo=""
     CDS             complement(<8173..9540)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890928.1"
                     /locus_tag="NRO40_RS02030"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02030"
                     /product="rhodanese-like domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFFVDTIRTEGLGNRSYLAGGAEHAVAVDPPRDVDRVLAAVAARG
                     VRLTHVVETHVHNDYVTGGPDLARLTGAAYLVPAAARVSCAHVPVTDGDRTPIDTGLVL
                     RALATPGHTPHHTAYVLEDSGTAVAAFTGGSLLIGTVGRPDLVEPGLTERLARAQYASA
                     HRLAAELPDDTAVLPTHGFGSFCASARNGAGGETSTIGAERAGNAAFAAADVDAFVADL
                     IAGLDDVPAYYAHMGPLNAAGPAPVDLTPPAVADADGIAARLAAGEWVVDLRSRVAFAE
                     GHVAGSFNFEAEGQLATYLAWLVPWGRPVTLLAATPRQLAEAQRELVRVGVDRPAAAAT
                     GDPTGWVRDGEALVSYPRGTFADLAEATARAPRDTVVLDVRRDRERAAAGHVEGSVHIP
                     LHLLRARQGEIPAGRVWVHCAAGMRAAVAASLLHAAGRDVVAVDDSFDAAAEAELPV"
     misc_feature    complement(9643..9660)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 18.25"
                     /tool="antismash"
     gene            complement(10001..11116)
                     /locus_tag="NRO40_RS02035"
                     /old_locus_tag="NRO40_02035"
     CDS             complement(10001..11116)
                     /EC_number="4.2.3.181"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982050.1"
                     /locus_tag="NRO40_RS02035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02035"
                     /product="selina-4(15),7(11)-diene synthase"
                     /protein_id="WP_058942809.1"
                     /sec_met_domain="T1TS (E-value: 1.1e-66, bitscore: 224.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGPGPTVPPLFSPIPPAIHPCHARADARTAAWAEIFRIGSDELRG
                     RLVSRSIGTFAARVLPEGREEVVSLLADFVLWLFGLGHCEEGERGRRPGDLAGELHRLL
                     RVAQNPEVPLLLDDPLAAGLRDLRLRIDRYGTQGQAARWVDALREYFFCLVWEAAHRRA
                     GTVPDLDDYTLTRLYDGATSAVLPLLEIGHGYELQPHERDRTAVRAAAEMASFVMTWDH
                     DILSYDEERKGGGATGSHLTVLRVLEHHEGLTPQQALRVAISQRDRVTCLYLRLTEHLA
                     AHGSPQLRQYLRTLGSFIRGAQDWGVGSARYTRPGDPTGTSSTFRDTPVDGGGEPLDIP
                     AVSWWWNLLPPGGDADATADPSTRAAARGTH"
     misc_feature    11141..11155
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            complement(11280..12716)
                     /locus_tag="NRO40_RS02040"
                     /old_locus_tag="NRO40_02040"
     CDS             complement(11280..12716)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010474924.1"
                     /locus_tag="NRO40_RS02040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02040"
                     /product="cytochrome P450"
                     /protein_id="WP_058942808.1"
                     /transl_table=11
                     /translation="MTTRGTDPAAGLTPPPGCPAHALGAGAPRRIYGPEAERDPRALYE
                     ELRRRHGPVAPVLLHGDLPAWIVLGHRENLEVMRSPSRFSNDSRLWRMFQEGRVPADSP
                     LRPMVEWQPMCVFADGAEHERLRSAVRDSVEQFDRRGVRRYVIRYTDQLVDAFAAEGRA
                     DLIEDFAEKLPMLVMTQLLGMPEEYGPQLVEATLDLLKGTETAVASNEFVVRTLRTLME
                     RKKAEPGHDFASRLLGHEADLTDDEVLEHLRLVLISANETTVNLIANTLRLVLTDRRFR
                     ANLAGGHMTLPDALEQVLWDDPPLSAITGRWATGDTVLGGRQIKAGDMLLLGLAAGNVD
                     PEIRPDLDRPLLGNRAHLAFSSGPHECPGQDIGRAIADTGVDTLLSRLPDLRLAVPESE
                     LRWSAAWLSKRLAALPVRFTPPASAVAPSGPAAPKDFASTAPGPLPAQVPGPRSDAQAA
                     PRSSASARRSWRSAFFRSAD"
     gene            complement(12713..13363)
                     /locus_tag="NRO40_RS02045"
                     /old_locus_tag="NRO40_02045"
     CDS             complement(12713..13363)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944873.1"
                     /locus_tag="NRO40_RS02045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02045"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_058942807.1"
                     /transl_table=11
                     /translation="MDYRSSEQHGSEQHGDGAVRGPRSEDVLPETATTAVKVVIVGGFG
                     VGKTTFVGSVSEIRPLTTEETMTQAGVGVDDTSGVDGKTSTTVAMDFGRISINQELVLY
                     LFGTPGQERFWFLWRGLFEGALGAVVLVDTRRLEVSFDVLGRLEERRVPFVVAVNTFPD
                     APAYPVEDLRVALDLPASVPIVPVDARERASSRDVLMTLMRYLQTLAMTQEAS"
     gene            complement(13344..13706)
                     /locus_tag="NRO40_RS02050"
                     /old_locus_tag="NRO40_02050"
     CDS             complement(13344..13706)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018846603.1"
                     /locus_tag="NRO40_RS02050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02050"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_058942806.1"
                     /transl_table=11
                     /translation="MSDAGGGDWEEASPERLYVITGGRSGGSAPAELDLVTLIVAKSGA
                     KPGMQPEHAAIVRLCQSPLSVAEISAYLGLPISVVTVLLGDLLADNRIVARAPVPPARL
                     PDRALIEAVIDGLQKL"
     gene            complement(13703..14113)
                     /locus_tag="NRO40_RS02055"
                     /old_locus_tag="NRO40_02055"
     CDS             complement(13703..14113)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010474920.1"
                     /locus_tag="NRO40_RS02055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02055"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_058942805.1"
                     /transl_table=11
                     /translation="MIKQQANMDWMLKDLAEGVPQTRHVVVLSADGLRMAQYGTDDDTA
                     DRLAAACAGLQSLAGAVASELPHSDGRMRLVVIEMDGGFFYLMAAGVGAYLAVLAGEGV
                     DAGLMGQRMRDLVLRIGEHLSSPPRQDGQGAR"
     gene            complement(14110..15609)
                     /locus_tag="NRO40_RS02060"
                     /old_locus_tag="NRO40_02060"
     CDS             complement(14110..15609)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349280.1"
                     /locus_tag="NRO40_RS02060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02060"
                     /product="sensor histidine kinase KdpD"
                     /protein_id="WP_058942804.1"
                     /transl_table=11
                     /translation="MVREESSPGSGSPRSAASFVWLLPAALIAVATGVAVTLVPTAARG
                     PVVACGVVSALALALLGAEVARRGRVIGELRRTVAARDTALARRHAETAHLAGTLLPDA
                     VRRLREGEFPEDVIGSLTAPEEHQAVVRVVVDAVVAEEDLRESAQRAFVNIARRVQAIV
                     HQQAQELREMEDRHGNRPEVFGDLLRIDHGTALIGRLADSIAVLGGARPGRQWSRAVPL
                     YSVLRGAMSRIIDYQRVELHSVTEVAVTGPAVEPLIHALAELLDNATRYSPPQTKVHLT
                     AVDVQSGIAVEIEDGGVSMSEEARKRAERMLRQAQQGIDLNDLGETPRLGLAVVGRLAQ
                     AYGFQVSLRSSAYGGVRAVVVVPQELITTVAAASGLAHGIGASSVPRTAVPAAPAVPAS
                     LPARAERPATGPMVDGEVPPTVERAPNGLPQRRRRQPLAEPPQSAAAAPAAPSEQASPA
                     PATPAPDQEPSPQVQPGMWLAAFQSGLTGEPNDASKGNSQQ"
     misc_feature    complement(15626..15640)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.79"
                     /tool="antismash"
     misc_feature    complement(15686..15699)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.14"
                     /tool="antismash"
     gene            15996..17309
                     /locus_tag="NRO40_RS02065"
                     /old_locus_tag="NRO40_02065"
     CDS             15996..17309
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1074: major
                     facilitator family transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537864.1"
                     /locus_tag="NRO40_RS02065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02065"
                     /product="MFS transporter"
                     /protein_id="WP_058942803.1"
                     /transl_table=11
                     /translation="MTTSVRDPAGAPGAARSPRALVAASVGNFIEWYEFGVYGYLATVV
                     ARNFFTPDGGDGAEALVRTYAAFALAFFFRPVGAVVFGRLGDRIGRRPTLILVLSLMTG
                     ATTLMGLLPTYAVAGAAAPWLLTALRVVQGLSAGGEFGGAVAVLTESAPPGRRGLYGAW
                     QSFTVALGLLAGAGAAALVATALTGPQVEAWGWRLPFLLALPLGLTALWLRLALEETPA
                     FRRARATAPAARPAASAREAAVAVVLGAGRLMAWSAAGYTFLVVLPSYLQASLGASLRE
                     ALAATVVANLGFAAAILPAGALSDRVGRRAVMVSGALLAAVAALPLLRLLQAPDAPPWA
                     KGVAVAAAGAVVGLMAGPGPAMLAEMFPTRVRHTGLGVTYALANAVFSGCAGLLVTELA
                     RRTGSADVPAYYVIVCCAVGTLALATLRGDDHRRALRE"
     gene            17444..18625
                     /locus_tag="NRO40_RS02070"
                     /old_locus_tag="NRO40_02070"
     CDS             17444..18625
                     /EC_number="2.7.1.170"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018381518.1"
                     /locus_tag="NRO40_RS02070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02070"
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="WP_058942802.1"
                     /transl_table=11
                     /translation="MRVIGMMSGTSYDAVDAAAAELTLTGDTLALRPLGMVSAGYPPAL
                     RAALAAALPPAATTLHEVCRLDTGIGRAFADVAVRADRELCGGRADLVVSHGQTVYHWV
                     ERGRVHGTLQLGAPAWIAEATGRTVVSDLRTRDVAAGGQGAPLVSLVDVLWLRGRPGRP
                     VALNLGGIANVTVATGPAGPVAFDTGPGNALVDAAVRLVTGGARDVDEDGVLAARGRVD
                     PALLRRLLAEPYYAAPAPKTTGKELFHGEYLRAALAAHGAPVAAEDLVATVTRLTAETV
                     AGAVRGLGGTEVVSSGGGVRNPTLTAMLRAALGRIPLRVSDELGLPAAAKEAYAFAVLG
                     FLTILGLPGTVPGCTGARHARVLGSVTPGAHGLRLPQPAPAPPVRLDVLPPRR"
     gene            19672..20901
                     /locus_tag="NRO40_RS02080"
                     /old_locus_tag="NRO40_02080"
     CDS             19672..20901
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389183.1"
                     /locus_tag="NRO40_RS02080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_02080"
                     /product="cytochrome P450"
                     /protein_id="WP_058942801.1"
                     /sec_met_domain="p450 (E-value: 1.5e-19, bitscore: 68.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEDTVAPPPLEPPPVRSWPALDLKATDFDPVLEELMRERPVSRI
                     QLPHGDGWAWLVTRYEDVKAVVNDPRFSRAPVPDMTVTRITPHFKPRPGSLAFAESSDH
                     HRLRRAVAPAFSARAVERLREGAREMLDELVSDTLRDGPPADLVDRVLQPFPTTVICEL
                     MGVPDADRERMSGWVSDILFTAKGAAATGRAKDEMYGWFAREIAARAADPGAGEDILSL
                     LGAAVAAGDITQEEAVGLVGPVQIGGEAVTNNCGNMLYLLLTRPQLRERLREEPEARPR
                     ALDELLRYIPHRSSVGLARIALEDVELRGVRIAAGDAVYVSYLAANRDPEVFPDPERID
                     VDRSPNPHVSFGHGPHFCTGALLARMEIELLVETFLDRLPDLRLAVPAERVPWRRSALI
                     RGPEALPVTW"
     misc_feature    complement(21008..21022)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 23.21"
                     /tool="antismash"
     misc_feature    21009..21023
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 21.93"
                     /tool="antismash"
ORIGIN
        1 gaccggccgt ggcggctccg gaccggccgt gcgcgccccc agtgggcgcc ccggagcggc
       61 cgggaaggcc cgggagccgg atcggggacg tcggcgagcc ggccgatcgc ccgggcgagg
      121 gccggggccc gcgggcgggg cctaccggcc ggttggtgag taggctcgaa agacaccgtc
      181 gtaccgggcg gggcgcgcgg acgggtccgg tcgcgcgccc ggcgcacccg gtggcaccgc
      241 cgggctccgg cggcgcggac gacgctggtg cgcgggtcca ccaggaggtt cacatgagca
      301 gcacagcacc gaggatcaac gccctgcccg ctccgcaccg ggagcggctg ctggcgctcg
      361 ccgaggaggt gtcgttcgaa ccgggcgagc gggtcttcga cgaacaccgc cccgcggacc
      421 ggttctgggt ggtccgcacg ggcgcggtca atctggactc gcgcgtgccg ggcagccgcc
      481 gtcccgccgt catcgagatg ctcggccacg gcgagctcgt gggcctgtcg tggctcttcc
      541 cgccgtacga gtgggagctc ggcgccgagg cgatgagcct ggtgcgggcc tacgagttcg
      601 acgcggcggt ggtgcgcacg ctgtgcgagg cggagccgcc cttcggactg gcgctgacgc
      661 agtgggtcgg gcaggtgctg tcccaccggt tgcaggcgac gcgggaacgg ctgctcgaca
      721 tgtacgcccc gcacggcagc ggcgttctct gacggccggg cggggacggt tgcggcgttc
      781 cgtccgtttc ccgggtgtca ccggcgagtg ccggccgcgc gcgagcggcg cgtcccccat
      841 cctcggtggg gggaccgagc gaagggacga gcgagcgaat gaggcaccgc agcgtggccg
      901 atctgatgac gccggaggtc gtcgcggtgc agcgcggcac gtccttcaag gagatcgcgc
      961 ggctgctcga cgagttcggc atcaccgctg tccccgtggt cgacggggac ggccggccgg
     1021 tcggcgtggt ctccgaggcg gacctgctgc accggcacac ctccggcgag cagggaccga
     1081 acacgaacac cgccgagggg ctgatgtcca gccccgccgt cgtggcgcgg ccccactgga
     1141 gcgccgtcga ggcggcccgc gtcatggagc gccggcgcat caagcggctg cccgtcgtgg
     1201 acgggacggg gcggatcatc ggggtgctca gccgcaggga cctgctccag ctgttcctgc
     1261 ggcgcgaccg cgcgatccag gaggagatcc tggaggacgt cgtgacccgc acgatgggac
     1321 tggcgccgtc ggccgtcacg gtcgacgtga acgacgggac ggtcaccctc agcggcatgc
     1381 tggagcgccg cagcctcgtg ccgatactgg tgcggctgtg cgagaccgtc gacggggtgg
     1441 tggacgtgga cgaccggctc gcctacgaga cggatgacac gggcgcgctg gcgtccggcg
     1501 acatgacggg ctgagggccg gcgacccggc ggggaccctc gccgccccgc cggtccccgg
     1561 ccgaggccgc cggcgggcgg gccgcgtccc cggtcacacg cgcaccgggc acgcgtcgcc
     1621 ggggccacac cggcgcacgg ggtgccgggg gcccacaacg gcgcacgggc ccggcgccgg
     1681 agccctgccg ggccccacac cggcccacgc ctgccggacc cctgccgggc ggcccacacc
     1741 ggcccacgcc tgccggcccc tgagcgggcg cacggccggc gggcgcccgc gcctatctcc
     1801 gcgtccgcgg cccctccccg cccgggtgcg gccgcgcgac cgtacgccgc ggcccctgcg
     1861 ctcgtgcggc ggcactcgtc ccggcacctc agctgaccgg cgtcgaccag ccgtacggcg
     1921 cgtcctcctc gacctcgccc gacaggcccg cgcccgcctc gccgatgtcc ttgtaggcca
     1981 ggcgcatcag ctgccgggac agatcgccca tcgcgcggct ggcggccagt tcgtcaccga
     2041 tcagcgggac gtcggcgtcc tcggggttgc ggcgggctga gccgcggccg gtgacggtgg
     2101 ccttgccggt gtcgagcacc gcgcgcgcct cggtggtgtc cccctcctcc accaactcca
     2161 tgttgatctt ccactcgagc gtccgggcca tggtgtcctc ctcgacacgt cgatcgggtg
     2221 cgggccggtg cgctgccggc cccgacttca ggatccaccc gtatgccccg gatggacgag
     2281 ccggaacgtc ggccgtcccc gtccgggcgc gttcggggcg gcccccggtt tgccgcccca
     2341 gtgccgggga accggggccc tccgaccctt ggggagcggc ccgcggccgc tcccgcccgt
     2401 cgggtgacgc ggcacccgga cctgacgtga cgtacggagg aggaacccat ggcgcaggcc
     2461 ccggcgcacc gcgcggtcgc ggtgggagtg gacggctcgc ccgagagcct cgcggccgcc
     2521 gagtgggcgg cacgggaggc cgcgctgcgc gggctgccgc tgcgtctggt gcaggcctgg
     2581 ctgcggcagc ccgtggacgg cgcgccggag cgggacggcg ccgccgagga gctgcgggcg
     2641 cgccacctgc tggaggaggt ggcggcggag gtccgcaccc ggcaccccgg gctggaggtg
     2701 acctccgcgc tcctgcccgc gccccccgta cccgcgctgc tgaccgccgg gaacgcggcg
     2761 gagatgctgg tcatcgggtc acgcgggcac ggcgcgctgc tcggcttcct gctcgggtcg
     2821 tccgggcagc aggtcatcgc ggaggcggac cgcccggtcg tggccgtgcg ctcgccgcgc
     2881 gaggacgggc cggggaccgg cgcggacggc ggcgaggtcg tcgtgggaca gcagggcgac
     2941 gcgcgggaga gcgcggcggt actgggcttc gccttcgcgg ccgcggcggc ccggggcgtc
     3001 ggggtgcgcg cggtacgggc ctggagcctg ccgtcggtgt acgcctacac ccccggggcg
     3061 ctgcgcccgg tcgacgaggc cgggggtctg gtgccgtacg aggagaaggc gctggcggag
     3121 gcgctggccc cgtggcggga gcggtacccg ggcgtgccgg tgagggagca cgtcgagctg
     3181 ggcagcgcgg gccaggtgct gctgtcggtg gtcaccggcg cgggcctggt cgtcgtgggc
     3241 cgccgggtgc ggcgcgcgcc ggtggggacg aggatcggtt cggtggcgca cgcggtgctg
     3301 caccacgcgc cgggcccggt cgcggtcgtg ccgcacgcct gaccggctcc cgccgcacgg
     3361 tgccgtgacc gctccggcgc ggggcgggcg gtccgggcac ccgcggtggc acgctggtcc
     3421 tggagggaac ccgcccgttc gcaccgaccc acttcagccg gaggacgtgc agcgatggtc
     3481 cgttacgtgt acgacgtcgc cgaggagccg ggagacggcc gcgacgggtc cggtccgccg
     3541 ggcggtccgg gcgtcgaccc cgtcgggctg ctgggcgaga agggcgccga tctgaccggg
     3601 ctgctgcgcc tggggctgcc ggtaccggcc ggcttcaccg tgaccagcga ggcgtgtcgg
     3661 gtgttcctcg cgaccggggc gccgcccccc ggactcgacg cggagctggc ggcgcacctg
     3721 gcccgcttgg aacgtgccgc cgggcggcgg ttgggacgcg tggacgaccc gctgctgctc
     3781 tcggtgcggc ccggggcacg ggtcgccgta ccggggctga tgccgacggt cctcgacgtg
     3841 gggctgaacg atcacgccgt gctggggctg gccgggaccc cggcgcggga gcggttcgcg
     3901 tgggactcct accggcgcct ggtacgggcg ttcggcaccg cggtgatggg ggtggacccg
     3961 gcgctcttcg acggcgtgct gcaccggatc gaggaccagc accatgtcgc cgacgactcg
     4021 cggctggacg cctgcgacct gatccggatc gtcgagacgt acaaggacgt ggtccgcgag
     4081 cggaccgggg aggacttccc gcaggacccg gtcgagcagc tgcaccgggc cgtgcgggcg
     4141 gcgttcgctt cctgggccgg cgagcccgcc cggctccacc ggcgccgggc ggggctgccg
     4201 gacgagccgg gcgtggccgt gaccgtgcag acgatggtct tcggcaaccg ggacgccgcg
     4261 tcgggcagcg gcgtggccct cacccgcgac ccggtcgccg gcgggcccgg ggtgtacggg
     4321 ggctatctgc ccggcgcgca gggcgaggac gtcgcctccg gtacacgcga cccgctgccg
     4381 ctggcggagt tcgcgcggct cgacccggac gcgtacgcgg cgctgtgcgg gcacctgcgg
     4441 cggctggagg agcaccaccg ggacgtgtgc ggcgtggcgt tcaccgtcga acgcggcagg
     4501 ctgtggacgt tgcggagctt cgtcggcgag ccggccgttc gggcggcgac ggccggcgcg
     4561 gcggcgcggc ccgccgccga cggcgcggca cccgggcgga caaaggacga ccggccggac
     4621 tgaggcccga gcggccgggc cgagcccagg gcggccggac tcggtgcggg ccggccgcct
     4681 cgcgggcggg ctgtcatccc tggccggcgg ggccctcctc gtccagcacg cgccggaccg
     4741 cctgggccgc cgtcgtgagg cccagcctgt ccagcgtctc gacgcactcc agcaggatca
     4801 ggtcggtcac cacggccatc tccgtgccga agcggtcccg ctccgccagg tcctcgggcg
     4861 tcacggcgcg gcgcagctcc cccacccgct cggccagggc ctcgcgccgc tcctccagtt
     4921 cggcgatcgc gcgcaccgcg ccgacgatct cctcgtcgct cacaccgctc atcggactcc
     4981 cgtctccttc gctcacacca ggaagagcag acgccgggcc ccggggtcac gtccgcgggc
     5041 gggaatgtga cgagggccgc acccggcagc gcaggggcac cgtggagtgg agcgtcagcc
     5101 ccgtgtcgac cggcacgtcg tgctcctccg cctccagttc gtactcctgg aggaccaccg
     5161 ccagggcgag ggccgacatc agcatcgaga agtgctgacc gatgcaggcc cgggggccgc
     5221 cgccgaaggg gtaccaggcg tagcggtgac gattcttctc ctgctcgggc gtgaaccgtc
     5281 ccgggtcgaa gcgctccggg tcgggccagt ggcgggtgtg gcggtgggtg acccacgggg
     5341 ccacgaagac atcggcgccg gccgggatga cgtggtcccc gaccggggtg gcggtgacgg
     5401 cgcgccggct gacgatcgga ccggccgggt agaggcgcag ggcctccttg acgacccggc
     5461 cgaggtacgg cagcgcggtc aggtccgcgg cgcgcggcgc gcggccgccg aggacccggt
     5521 ggacctcctc gcgggcgagg cgctgctcgc gcgggtggcg ggccagcagg tgcagggcga
     5581 acgagagcga gctggcggtg gtctcgtggc cggcgagcag gaagatcagc acctggtcgc
     5641 ggacctcgga cgggtcgagg cggtcgccgt cctcgctgcc ggcctgggtg aggagggtga
     5701 gcaggtcctc ctgggcgggt gctccgtcgg cgcgccggcg ggcgatgatg cggtcgcact
     5761 cggcgtacag ttcggccacc gcggcggcgg cccggcggtt gccgggcgtg ggccactcgc
     5821 gcgggagggt gacgggcgcg taggagcggc cgaggacgta gtcgttgatg acgggaaagc
     5881 agcgcgcgat gacgtcgacg gcggactcga cgtcggtgcc gaacaggacg cgggcgaccg
     5941 agcgcagcgt cagctcgttc gtctcgtcgg cgaggtcgac ggtggcgccg ggggcgtccc
     6001 gccaggcacg ggtgagggcg gtggcctcgg cggtgagggc gtcggcgtag cggtcgacgc
     6061 gtcggggcgt gaacaacggc tgcaccagcc gccgttggcg caggtactcg tcatcctggc
     6121 tggtgagcag gccgttgccg agcgacaggc gcacctcctg gtagaaaacg ttgtccttgc
     6181 ggaagttcgc ggacgaggtg gccagcacct gctgggcgcc ctcggcggag aacacggcgt
     6241 acaactccga acgcagcccc ggtggtcccg ccgtgatccg tacgacgtcg ccgtgtgccc
     6301 ggtgggcggc caggagggtc ccgaggaggt cccgcttgag gtcgaggagc gagccgacga
     6361 ggggcaggcc cgacgggccg gggacgcgcc tgctggtgat ggtcgtcatc gatctctccc
     6421 tgcgccggtc ggacctgggg cacgacccgg tgcgggcggc cgcgcacggg gcgattcttc
     6481 cgcagaagcc cccacggggg agtcatgatc gcgtcagggc aggcgccttt ccggccgttg
     6541 tgacctgcgc cccggcgacc gccgcaccgc cccggcgacc cgcctgtccg cccccgccgg
     6601 agcggcgggg cgcggtacct taccccctgg ggtatccggg gtggccgggg tggccggagc
     6661 atcggtgagg aggggtcgtg gagctcgaac tcacgggcgc ggagctgaag tcggtgctga
     6721 accggctgcg gcgggcgcag gggcagatct ccggggtgat ccgcatgctg gaggagggcc
     6781 gcgactgcga ggaggtcgtg acccagctgg ccgcggcggc gcgcgccctc gaccgggcgg
     6841 gtttcgcgat catcgccacg ggcctgcggc agtgcatgac gggcgacggt ggcggcacgg
     6901 ccggcgaccg cgaggaggcg cgcacccgcc tggagaagct gttcctctcc ctcgcctgag
     6961 gtccgcccgg cgccgccggg gggtcacagg agccgggggg tcacaggagg cgggcggtcc
     7021 cgtcgacggc catgagcgcg gccaccgcga gcagcgcgct cccgaagatc cgacgcaggg
     7081 cggtggccgg gacccgcgcg gcgagacgcc ggccgtccca ggcggcgagg acggcggcgc
     7141 cggtgaaggg cgccaccacg gcccagtcca cgggggccgc cgtaccggcg cgggcgacga
     7201 gcgcggtcag cgcgttcgcc gtgatgacga gcaggctggt gccgaccgcc gcgcgcatgc
     7261 gcaggccgac catgccgacg agggccggta cggcgaggaa gccgcccccg acgccgagga
     7321 agccggtcaa cgcgcccacc cctgccccgg ccccggcggc ccgcagcggc cgcggccgcg
     7381 gggcaccagg cgtgggaccg tcgcgcgccg ggggctcggc ggccgggggc tcggccgggt
     7441 cccgggcgtc gtcgtccggg tcggcggcgg ggcgcagcat ccggagggcc gccagggcgg
     7501 cgacggcggc gaacgccagg gtgaggacgg gccgcggcac cccgtccgcg agcgacgcgg
     7561 tgaggacggc cggtaccgcg ccggcggcgg cgaagagcgc gccggccgtc caccgcaccc
     7621 ggccgtcgcg ggcgtgcccg tagagcgcgg tcgcggaggt gacggcgacg acgacgagcc
     7681 cggcggtcgt ggcctcgacg gggccgaagc cgagcaggta gatcagcgcg ggtgcggcca
     7741 ggacgccgcc gcccccgccg agcgccccga gcgccaggcc gacgacggcg cccgcggtga
     7801 gggccaggac gaggacggtc acgctatcga gccgcggttc ccgcccgcgt cgaccaccgg
     7861 gaggccggcg cccgcccagg cgtgcatgcc gccttcgacg tcgacggccc gccgcccccg
     7921 ccgggtgagg agtgccgccg cgtgctggga gcgctgcccg gagcggcaga tcaccacgag
     7981 cggccggtcg agcgcggcgg cggggaccgg ggcgccggcg cggagggcgg agagcggtgc
     8041 gtggaccgcc ccgggcgcgt ggcccgcccg ccactccggt tcctcccgca cgtcgaggag
     8101 gacggccccg ccggccgcgg cggtccggtg gtgggcctgg cgggccgtca cgcgctcgca
     8161 gaggggccgc accacgggca gctccgcctc ggcggcggcg tcgaaggagt cgtcgacggc
     8221 gacgacgtcg cgtcccgccg cgtgcagcag cgacgcggcc acggcggccc gcatcccggc
     8281 cgcgcagtgc acccacaccc tcccggcggg gatctccccc tggcgcgcgc ggagcaggtg
     8341 cagggggatg tgtacggagc cctcgacgtg gcccgcggcg gcgcgctcgc ggtcgcggcg
     8401 cacgtcgagg acgacggtgt cccgcggtgc gcgggcggtg gcctcggcga ggtcggcgaa
     8461 ggtgccgcgg gggtaggaga cgagggcctc gccgtcccgt acccagccgg tcggatcgcc
     8521 ggtggcggcc gcggcggggc ggtccacgcc gacgcggacg agttcgcgct gtgcctcggc
     8581 gagttgccgg ggggtcgcgg cgagcagggt gacgggacgc ccccagggga cgagccaggc
     8641 gaggtaggtg gcgagctggc cctccgcctc gaagttgaac gacccggcga cgtgcccttc
     8701 ggcgaaggcc acgcggctgc gcaggtccac gacccactcc cccgccgcga ggcgcgcggc
     8761 gatcccgtcg gcgtcggcga cggcgggcgg tgtcaggtcg acgggggccg ggccggcggc
     8821 gttcagcggg cccatgtgcg cgtagtaggc ggggacgtcg tcgaggccgg cgatgaggtc
     8881 ggcgacgaag gcgtccacgt ccgcggcggc gaaggcggcg ttgccggccc tctccgcgcc
     8941 gatggtcgac gtctcgccgc cggcgccgtt cctcgcggag gcgcagaagc tgccgaagcc
     9001 gtgcgtgggc aggacggcgg tgtcgtcggg gagttcggcg gcgagccggt gcgcggaggc
     9061 gtactgggca cgggcgagcc gttcggtgag tcccggctcg acgaggtcgg ggcggccgac
     9121 ggtgccgatc aggagggagc cgccggtgaa ggcggcgacc gcggtgcccg agtcctccag
     9181 gacgtacgcg gtgtggtgcg gggtgtggcc gggggtggcg agggcccgca ggaccagtcc
     9241 cgtgtcgatc ggggtgcggt cgccgtcggt caccgggacg tgggcgcagg agacccgcgc
     9301 ggcggcgggg acgaggtagg cggcgcccgt gaggcgggcg aggtcgggac cgccggtgac
     9361 gtagtcgttg tggacgtgcg tctcgacgac gtgcgtgagg cgcacgccgc gcgccgcgac
     9421 ggcggcgagc acccggtcga cgtcgcgcgg cgggtcgacg gcgaccgcgt gctccgcccc
     9481 tcccgccaga tagctgcggt tgccgagccc ttcggtcctg atggtgtcga cgaagaacac
     9541 cagcacactc ctttcggcgc ttccgggtcg cggaacgtac ctccgggggt gtccgggcga
     9601 gcgtggcccg gtacccccgg gggtatcgtt cgccgtgcgc cggtgccgca caaggggaga
     9661 tcgagccgtc cccaccgccc acgggacggg ccgggtcggc cggaaggcgg cgggatcggg
     9721 cgggtcggcc ggggatccgg cggggcgacg gaacgggtcg ccccctccgc gcgcgacgca
     9781 cgccccccgg aagccgaggc tcccgcccca ggcccgcgcc cgccttgccc acggaccctg
     9841 atccggaccc cggccccgga ccgccgtgtg gcggaccccg cgccgcacct acgcacgcct
     9901 cagccgtggc gcggcccgac ggtcacgggc acccggtcgc ggtgcgccac cgccgaggcg
     9961 acctcgcggg gggcgcgtag gcctggctgc gccgggggcc ctagtgggtc ccgcgcgcgg
    10021 ctgcgcgcgt cgacgggtcg gctgtggcgt ccgcgtcccc gccggggggc aggaggttcc
    10081 accaccagga gacggcgggg atgtcgaggg gctcgccgcc accgtccacg ggggtgtccc
    10141 ggaaggtgga ggacgtcccg gtcgggtcgc ccgggcgcgt gtaccgggcg gagccgacgc
    10201 cccagtcctg ggcaccccgg atgaagctgc cgagggtgcg caggtactgg cgcagctgtg
    10261 ggctgccgtg tgcggccagg tgctcggtga gacgcaagta caggcaagtg acccggtccc
    10321 gctgggagat cgccacgcgc agggcctgct gtggcgtcag cccctcgtga tgctccagga
    10381 cgcggagcac ggtgaggtgg gagccggtgg cgcccccgcc cttcctctcc tcgtcgtacg
    10441 agaggatgtc gtggtcccag gtcatgacga acgaggccat ctccgccgcc gcgcgcaccg
    10501 ccgtgcggtc ccgctcgtgc ggctggagct cgtagccgtg gccgatctcc aggagcggca
    10561 gcacggccga ggtggcgccg tcgtagaggc gcgtcagggt gtagtcgtcg aggtccggga
    10621 ccgtaccggc ccggcggtgg gccgcctccc acaccaggca gaagaagtac tcgcgcaggg
    10681 cgtccaccca gcgcgccgcc tggccctggg tgccgtaccg gtcgatgcgc agccgcaggt
    10741 cccgcaggcc ggccgccagc gggtcgtcga ggagcagcgg cacctcgggg ttctgggcga
    10801 cgcgcagcag gcggtgcagc tccccggcga ggtcgccggg gcggcggccg cgctcgccct
    10861 cctcgcagtg gccgaggccg aagagccaca ggacgaagtc cgcgaggagc gagacgacct
    10921 cctcgcgccc ctcggggagg acacgggcgg cgaaggtgcc gatggaccgg gagacgagcc
    10981 gcccgcgcag ttcgtcggag ccgatgcgga agatctcggc ccaggccgcc gtccgggcgt
    11041 cggcccgggc gtggcacggg tggatggccg gcgggatggg agagaagagc ggcggcactg
    11101 tcggaccggg ccccactgcg gcctcctcct cgtcgcggtg cgacgtgtcg ttccggggca
    11161 acgaagcgtc agaacacgcc acttgcgcgc cgaagtgatc aactacggcg catagtagcc
    11221 acccatggcc gccgttccca ccgggacgat ccccgccgac ccggacatac cccccgacgt
    11281 cagtcggcgg agcggaagaa agcactccgc cagctcctgc gggcggacgc cgaggaccgc
    11341 ggcgccgcct gggcgtccga cctcgggccg ggtacctgtg cgggcagggg ccccggcgcg
    11401 gtcgacgcga agtccttcgg cgcggccgga ccgctcggcg ccaccgcgga ggcgggtggc
    11461 gtgaaccgca cggggagggc cgccagccgc ttcgacaacc acgcggcgga ccagcgcagt
    11521 tcgctctccg gcacggcgag ccgcaggtcc ggcaggcgcg acagcagcgt gtccacaccg
    11581 gtgtccgcga tggcgcggcc gatgtcctgg ccggggcact cgtggggccc gctgctgaag
    11641 gcgaggtgcg cccggttgcc gagcagcggc cggtcgaggt cggggcggat ctccggatcg
    11701 acgttgccgg cggcgagccc gagcagcagc atgtccccgg ccttgatctg ccggccgccg
    11761 aggacggtgt ccccggtcgc ccagcgcccg gtgatcgccg acagcggcgg gtcgtcccac
    11821 aggacctgct ccagcgcgtc cggcagcgtc atgtggccac cggccaggtt cgcgcggaag
    11881 cggcggtcgg tgaggaccag ccgcagcgtg ttggcgatga ggttgacggt ggtctcgttg
    11941 gcggagatca gcacgagccg caggtgctcc agcacctcgt cgtccgtgag gtcggcctcg
    12001 tggccgagga gccggctggc gaagtcgtgc ccgggctcgg ccttcttgcg ctccatgagc
    12061 gtccgcagcg tccggacgac gaactcgttg ctcgcgaccg ccgtctcggt gcccttcaac
    12121 aggtcgaggg tggcctcgac gagttgcggc ccgtactcct cgggcatgcc gagcagctgg
    12181 gtcatcacca gcatcggcag cttctccgcg aagtcctcga tgaggtcggc ccggccctcc
    12241 gccgcgaacg cgtcgacgag ctggtcggtg tagcggatga cgtagcggcg cacgccccgg
    12301 cggtcgaact gctccacgct gtcgcggacg gccgaccgca ggcgctcgtg ctcggccccg
    12361 tcggcgaaga cgcacatcgg ctgccactcg accatggggc gcagcggcga gtcggcgggg
    12421 acccgcccct cctggaacat ccgccacagc cgggagtcgt tggagaaccg cgacggcgac
    12481 cgcatgacct caaggttctc ccggtggccc aggacgatcc aggcgggaag gtcgccgtgg
    12541 agcaggaccg gggcgaccgg gccgtgccgg cggcgcagct cctcgtacag ggcccgcggg
    12601 tcgcgctcgg cctcgggacc gtagatgcgg cgcggggcac cggccccgag ggcgtgggcg
    12661 gggcagccgg gaggcggggt gaggccggcg gccgggtcgg tcccgcgggt ggtcatgacg
    12721 cctcctgggt catggcgagg gtctggaggt agcgcatcag cgtcatcagg acgtcccggc
    12781 tggaggcgcg ctcgcgggcg tcgacgggca cgatcggcac ggacgcgggc aggtcgaggg
    12841 cgacgcgcag gtcctcgacc gggtacgccg gcgcgtccgg gaaggtgttc acggcgacca
    12901 cgaacggcac acggcgctcc tccagccggc cgagcacgtc gaagctcacc tccaggcggc
    12961 gggtgtcgac gagcacgacc gcgccgagcg cgccctcgaa caggccccgc cacaggaacc
    13021 agaagcgctc ctggccgggc gtgccgaaca ggtacaggac cagctcctgg ttgatgctga
    13081 tccggccgaa gtccatggcg acggtcgtcg aggtcttgcc gtcgacaccg gaggtgtcgt
    13141 cgacgccgac cccggcctgc gtcatcgtct cctcggtggt gaggggacgg atctcgctga
    13201 cggaaccgac gaaggtggtc ttgccgacgc cgaacccgcc gacgatcacc accttgacgg
    13261 cggtggtggc cgtctccggc agcacgtcct cgctgcgcgg cccccgcacc gcgccgtcgc
    13321 cgtgctgctc ggagccgtgc tgctcagagc ttctgtagtc catcgatcac tgcctcaatc
    13381 aacgcgcggt cggggagtcg ggcgggtggg acgggagcgc gggcgacgat gcggttgtcg
    13441 gcgaggaggt cgccgagcag caccgtgacg acactgatcg ggaggcccag gtaggcggag
    13501 atctccgcca ccgacagcgg cgactggcac agccgcacga tcgccgcgtg ttcgggctgc
    13561 atcccgggct tcgccccgga cttcgccacg atgagcgtga cgaggtccag ttcggcgggc
    13621 gccgacccgc cgctgcgtcc ccccgtgatc acgtagagcc gctcgggact ggcttcctcc
    13681 cagtcaccgc cgcccgcgtc gctcacctgg cgccctgccc atcctggcgc ggcgggctgc
    13741 tcaggtgctc cccgatccgc aggacgaggt cccgcatgcg ctggcccatc agccccgcgt
    13801 cgacgccctc gccggcgagc acggccaggt acgcgccgac gcccgcggcc atcaggtaga
    13861 agaagccgcc gtccatctcg atcacgacga gccgcatgcg cccgtcgctg tgcggcagct
    13921 ccgaggcgac ggcgccggcg agcgactgga gcccggcgca cgccgcggcg agccggtcgg
    13981 cggtgtcgtc gtcggtgccg tactgggcca tgcgcagacc gtcggcggag agcacgacca
    14041 cgtgtcgggt ttgcggcacg ccttccgcga ggtccttgag catccagtcc atattggcct
    14101 gctgcttgat cattgctgcg agttcccctt gcttgcgtcg ttgggctccc cggtcaggcc
    14161 gctctggaag gcggccagcc acatcccggg ctgcacctga ggtgacggct cctggtcggg
    14221 agccggggtc gcgggcgccg gcgacgcctg ctccgagggt gcggccggtg cggcggccgc
    14281 ggactgcggc ggctcggcga gcggttgcct gcggcgccgc tgcggcaggc cgttcggggc
    14341 ccgctcgacc gtcggcggga cctcgccgtc caccatcggg ccggtcgcgg gacgctccgc
    14401 gcgggccggg agggaggcgg ggacggccgg ggcggccggg acggcggtgc ggggcacgga
    14461 ggaggcgccg atgccgtggg cgaggccgga ggccgcggcg acggtggtga tcagttcctg
    14521 cggcacgacg acgacggcgc ggacaccgcc gtaggcggag gagcgcagcg agacctggaa
    14581 gccgtacgcc tgcgccagcc ggccgacgac ggcgaggccg aggcgggggg tctcacccag
    14641 gtcgttgagg tcgatgccct gctgggcctg acggagcatc cgctcggcgc gcttgcgggc
    14701 ctcctcgctc atggagacgc cgccgtcctc gatctcgacc gcgatgccgg actgcacgtc
    14761 gacggcggtc aggtggacct tcgtctgcgg cggcgagtag cgggtggcgt tgtcgaggag
    14821 ctcggcgagc gcgtggatga ggggctcgac ggcggggccg gtgacggcga cctcggtgac
    14881 ggagtgcagt tcgacgcgct ggtagtcgat gatccgcgac atggcgccgc gcagcacgct
    14941 gtacagcggt acggcccggc tccactggcg gcccgggcgg gcaccgccga ggacggcgat
    15001 cgagtcggcg aggcggccga tcagggcggt gccgtggtcg atgcggagca ggtcgccgaa
    15061 gacctcgggg cggttgccgt gccggtcctc catctcgcgc agctcctggg cctgctggtg
    15121 cacgatcgcc tggacgcggc gggcgatgtt gacgaaggcg cgctgcgcgg actcgcgcag
    15181 gtcctcctcg gcgacgacgg cgtcgacgac gacacggacg acggcctggt gctcctcagg
    15241 ggccgtgagc gaaccgatga cgtcctcggg gaactccccc tcgcgcagcc gccgcacggc
    15301 gtccgggagc agcgtgcccg ccaggtgggc ggtctcggcg tgccgtcggg ccagggcagt
    15361 gtcgcgggcg gcgaccgtac ggcgcagctc cccgatcacc cgcccccggc gtgcgacctc
    15421 ggcgccgagc agggccagcg ccagggcgga caccaccccg caggccacga ccggcccccg
    15481 tgcggcagtc ggcaccaggg tcacggcgac cccggtggcg acggcgatca gagcggcggg
    15541 cagcagccac acgaaagatg ccgcggaccg cgggcttcca cttccgggcg acgattcctc
    15601 gcggaccatc agcaccctca aacccatcga cgaaaaagat caatgacgac gagcgccgag
    15661 catagcccgt tcgggtgagc actcttgacg cagggtcacg taatggcccg atgtttgccc
    15721 aaggttccgc ttcttgtgaa tccggtgcag agggcgggac ttgatcccct tggcgaggtt
    15781 ctcccgcgcc cccgtgccgg acaccccgtc agcgcggtgc ccttcgctca ccgcaacgcc
    15841 caccggccgc cgcacgggcc cggccccggt ccgcggcgcg gcggtggtcc cccgctccgc
    15901 gccccggcgc gacggccgcg cgggcacggc ccgcggcgac gcgctggcct tgcggttgct
    15961 cccgtgaacg ccccaccgcg tggcaggctc tgcccatgac cacgtccgta cgggacccgg
    16021 cgggggcccc cggggcggcg cgctcgcccc gggcgctcgt cgccgcgtcg gtgggcaact
    16081 tcatcgagtg gtacgagttc ggcgtgtacg ggtacctcgc gacggtcgtc gcccggaact
    16141 tcttcacccc ggacggcggc gacggggcag aggcgctcgt ccgcacctac gccgccttcg
    16201 cgctggcctt cttcttccgg cccgtcggcg ccgtcgtctt cggccggctg ggcgaccgga
    16261 tcgggcggcg gccgacgctc atcctggtgc tctcgctgat gaccggcgcg acgaccctga
    16321 tgggcctgct gcccacgtac gccgtggcgg gggccgccgc gccctggctg ctgacggcgc
    16381 tgcgggtcgt gcagggcctg tcggcgggcg gtgagttcgg gggcgcggtc gcggtgctga
    16441 ccgagtcggc gccacccggg cggcggggcc tgtacggggc ctggcagtcg ttcacggtgg
    16501 ccctcgggct gctcgccggg gccggggccg ccgcgctcgt cgcgacggcg ctgaccggcc
    16561 cgcaggtcga ggcgtggggg tggcggctgc cgttcctcct ggcgctgccg ctggggctga
    16621 ccgcgctgtg gctgcggctg gccctggagg agacgccggc gttccgccgg gcccgcgcca
    16681 ccgcgcccgc ggcccggccg gccgcgtcgg cacgggaggc ggcggtggcg gtcgtcctcg
    16741 gcgcggggcg gctgatggcg tggtcggcgg ccggctacac cttcctcgtg gtactgccct
    16801 cctacctcca ggcgtccctc ggagcgagcc tgcgggaggc gctggccgcg accgtggtgg
    16861 ccaacctcgg cttcgccgcc gcgatcctgc cggccggcgc gctgagcgac cgggtcggcc
    16921 gacgggccgt catggtgagc ggcgcactgc tggcggcggt ggcggcgctg cccctgctgc
    16981 gcctgctcca ggccccggac gcaccgccgt gggcgaaggg cgtcgcggtc gcggccgccg
    17041 gggccgtggt gggcctcatg gccgggcccg gtccggccat gctcgcggag atgttcccca
    17101 cccgcgtccg ccacaccggg ctcggcgtga cgtacgccct ggccaacgcg gtcttctcgg
    17161 gctgcgccgg actgctcgtc accgagctgg cccggcggac cggcagcgcc gacgtccccg
    17221 cgtactacgt catcgtctgc tgcgccgtcg gcaccctcgc cctggcgacg ctgcggggcg
    17281 acgaccaccg gcgcgcgctg cgggagtgac cacgccccgg ccggccgggg gcccggcggt
    17341 cgctggtgaa gccgggcaga cggggggaac ggaggctcac ccaccgggtg gggccggccg
    17401 gacgcgaaag acggacggga gaggtccgcg gagaggtgga gggatgcggg tcatcgggat
    17461 gatgtcgggc acctcgtacg acgcggtcga cgcggccgcc gcggagctga cgctcaccgg
    17521 ggacaccctc gcgctgcggc ccctcggcat ggtcagcgcc ggctacccgc ccgccctgcg
    17581 cgcggcgctg gccgccgcgc tgcccccggc cgcgacgacg ctgcacgagg tctgccgact
    17641 ggacaccggc atcgggcggg ccttcgccga cgtcgccgta cgggccgacc gggagctgtg
    17701 cggcgggcgc gccgacctcg tcgtctccca cggccagacc gtgtaccact gggtggagcg
    17761 gggccgcgtc cacggcacgc tgcagctcgg ggcgccggcc tggatcgccg aggcgaccgg
    17821 ccgtacggtc gtctccgacc tgcgcacccg ggacgtcgcg gcaggcggtc agggggctcc
    17881 gctggtgagc ctcgtggacg tgctgtggct gcgcggccgc ccggggcggc cggtcgccct
    17941 gaacctgggc ggcatcgcca acgtcaccgt cgcgaccggc cccgcggggc cggtggcctt
    18001 cgacaccgga ccgggcaacg ccctcgtcga cgccgccgtc cggctcgtca cgggcggcgc
    18061 gcgcgacgtc gacgaggacg gcgtgctcgc cgcgcggggc cgtgtggacc ccgccctgct
    18121 gcggcggctg ctcgccgagc cgtactacgc ggcgccggcg ccgaagacga ccggcaagga
    18181 gctgttccac ggggagtacc tgcgggcggc actcgcggcg cacggcgccc cggtcgccgc
    18241 cgaggacctc gtcgccacgg tcacccggct caccgccgag acggtcgcgg gggcggtacg
    18301 cggactcggc ggcaccgagg tcgtctcgtc cggcggcggc gtccgcaacc cgacgctgac
    18361 ggcgatgctg cgggccgcgc tggggcgcat ccccctgcgc gtctcggacg agctggggct
    18421 gcccgcggcg gccaaggagg cgtacgcctt cgccgtgctc ggtttcctca ccatcctcgg
    18481 cctgcccggc accgtgccgg ggtgcaccgg cgcccgccac gcgcgcgtcc tcggctcggt
    18541 cacccccggc gcgcacggtc tgcggctgcc gcagccggcc ccggcgccac cggtgcggct
    18601 cgacgtcctg ccgccccgcc ggtaggtccc cgcagccgcg cacgcacgcg acgcccgcgg
    18661 ggtccggcgc gcacccgcgc gccgcgcctc gccggtccgc ggccgtaccc gcgcggccca
    18721 ccgcccgtgt ggtcgtgccc gctcgcgcct cgccggtccg cggccctccc gtgcgcgacg
    18781 gaccgccggt gcgtggtcgt acgcgcgcgt caccggcccg cccgtgccgg gccgtgggcg
    18841 cgtcaccggc cgccggtgcc gggcccgtgc ccgcgcgacg gccgccggct ccccgaccgg
    18901 acacgcggac acgcggacgg gccggccggc gaggtcctgg tcggcccgtc gcgggacgcg
    18961 cgtcagcgga cggaggcgga gccgttctcc ggagggacgt tccccaggag gtgtgacagg
    19021 gcgctgtcac ccgtgaccgc cgtcgagttc tccgcgcact gctggtcctg cgtgtcgtca
    19081 gggggtcccg gacgccgatg ttgacgagca ggatgttctg cacgtcggcc gcgacgggta
    19141 cgccggcgca cggcttgttc agggagccct gggccagacc gagccgcggg ttcgccacac
    19201 cgccggtgac ggtgttgccg tacacctgct gggagtggtt gccgttctgc gtgtcgacgg
    19261 cgtggtcgcc gacggcgagg gccgccgggc gagcagaacc cgagggcggc tgcggcgacg
    19321 ccggcggtgg cgacgacctt cttgatcacg atccgtcctt ctcggcgagg gcccggatcc
    19381 cgggccgccc tgccaacccg gggacccggg gagcgtcagg gcccgcgggc ggtgacgcgg
    19441 ccgcattcac ccgttcgccg ccgggccccg cccccacgcg ggccccgggc cggcgggtcg
    19501 cggtccgggc ggtgggacgg accgtccgga gtagtccagc gggtggtccg cgcggccggg
    19561 gccgaaggtg agggaggggg ccgtccagga caccgtcggg cagcgccgtc ggccagcgtc
    19621 gccgtcggcc ggcgccgtcg ggagagatcg tcaggaaacg gagacacgcg cgtgatcgag
    19681 gacaccgtcg caccaccgcc cctggagccg ccgcccgtgc gctcctggcc ggcgctcgac
    19741 ctcaaggcca ccgacttcga cccggtgctc gaagagctga tgcgggagcg gccggtgagc
    19801 cggatccagc tgccgcacgg cgacggctgg gcgtggctgg tgacccggta cgaggacgtg
    19861 aaggcggtag tgaacgaccc gcgcttcagc cgcgccccgg tgccggacat gacggtcacc
    19921 aggatcaccc cgcacttcaa gccccggccc gggtcgctgg cgttcgcgga gtcgtcggac
    19981 caccaccggc tgcgccgcgc cgtcgcgccg gcgttctccg cgcgcgcggt ggagcggctg
    20041 cgggaggggg cccgggagat gctcgacgag ctggtgtccg acacgctgcg cgacgggccc
    20101 ccggcggacc tggtcgaccg ggtgctgcaa ccgttcccga ccacggtgat ctgcgagctg
    20161 atgggcgtgc cggacgccga ccgggagcgg atgagcggat gggtgagcga catcctcttc
    20221 accgcgaagg gcgccgcggc gacgggccgg gccaaggacg agatgtacgg gtggttcgcc
    20281 cgggagatcg ccgcgcgcgc ggcggacccg ggggccggcg aggacatcct gtcgctcctc
    20341 ggcgcggccg tcgccgccgg tgacatcacc caggaggagg cggtggggct ggtcggcccc
    20401 gtgcagatcg gcggcgaggc cgtcaccaac aactgcggca acatgctgta cctgctgctg
    20461 acccggccgc agctgcggga gcggctgcgc gaggagccgg aggcgcggcc ccgggccctg
    20521 gacgagctgc tgcggtacat cccgcaccgc tcgtcggtgg ggctggcgcg gatcgcgctg
    20581 gaggacgtgg agctgcgcgg cgtgcggatc gcggcggggg acgcggtgta cgtgtcgtac
    20641 ctggcggcca accgcgaccc ggaggtcttc cccgacccgg agcggatcga cgtcgaccgc
    20701 tcgcccaacc cgcacgtgtc gttcgggcac gggccgcact tctgcaccgg ggcgctgctc
    20761 gcgcggatgg agatcgagct gctggtcgag acgttcctgg accggctgcc ggacctgcgt
    20821 ctcgccgtgc ccgccgagcg ggtgccgtgg cggcgcagcg ccctgatccg gggtccggag
    20881 gcgttgcccg tcacgtggtg acggcgtgtc cgccccatcg gttccggtcg ccggaggggg
    20941 agggtcggaa tccggacacg cgccgtcccg ggcgaacggg cgtgattgac gcataaggga
    21001 gaggcgcgtg ggaccgttcc cacggagtcc ggaggggccg cgcggccggc cccgccgccc
    21061 ggcgcggcgg gacgcgcgag gcggcgcggg ggtcgccgga cccgtggagc gcgggt
//
