LOCUS       NZ_CP102332            22598 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Streptomyces changanensis strain HL-66 chromosome, complete genome.
ACCESSION   NZ_CP102332
VERSION     NZ_CP102332.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces changanensis
  ORGANISM  Streptomyces changanensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6817869)
  AUTHORS   Wu,H. and Han,L.
  TITLE     Streptomyces changanensis sp. nov., an actinomycete isolated from
            soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6817869)
  AUTHORS   Wu,H. and Han,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2022) College of Forestry (Academy of Forestry),
            Northwest A&F University, Northwest A&F University, Yangling,
            Shaanxi 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.9; Pilon v. 1.24
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 187.45x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024600715.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 19:18:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,071
            CDSs (total)                      :: 5,982
            Genes (coding)                    :: 5,812
            CDSs (with protein)               :: 5,812
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 170
            CDSs (without protein)            :: 170
            Pseudo Genes (ambiguous residues) :: 0 of 170
            Pseudo Genes (frameshifted)       :: 70 of 170
            Pseudo Genes (incomplete)         :: 131 of 170
            Pseudo Genes (internal stop)      :: 9 of 170
            Pseudo Genes (multiple problems)  :: 37 of 170
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:13:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 244460
            Orig. end                         :: 267058
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102332.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22598
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="2"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22598
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22598
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12598](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12598
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(170..736)
                     /locus_tag="NRO40_RS01095"
                     /old_locus_tag="NRO40_01095"
     CDS             complement(170..736)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS01095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NRO40_01095"
                     /product="hypothetical protein"
                     /protein_id="WP_157901787.1"
                     /transl_table=11
                     /translation="MRLIRAEAARHDWERMTCGCGASAAHLARDLLESARETPAPGGPD
                     GLLEGHVWSPATLWEPAPAVTSVALAALADTIPPAARTWFLDLLQLTVAGEGTDPVSAR
                     RGLDLPERCRTITRQGLWSLYGEVVSGRCVGDAGTAFEILTVVEPDRARLRRVREAVPD
                     LLPVCCRTGFCDGPPEPEPAASGAE"
     gene            complement(881..1267)
                     /locus_tag="NRO40_RS01100"
                     /old_locus_tag="NRO40_01100"
     CDS             complement(881..1267)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS01100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NRO40_01100"
                     /product="hypothetical protein"
                     /protein_id="WP_058940769.1"
                     /transl_table=11
                     /translation="MSETDKNKSSGKDTATDTSAANGRARTATSTARRTARDTTRAATD
                     GAGEAGKATGGVLATQAQALTSTVNGVWRKAAVPALGLLKANAVTAGGVAAAATAVAVG
                     AYAGGRRSVLRAHGPVTRLTGGRI"
     misc_feature    complement(1267..1285)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.12"
                     /tool="antismash"
     gene            complement(1749..2087)
                     /locus_tag="NRO40_RS01105"
                     /old_locus_tag="NRO40_01105"
     CDS             complement(1749..2087)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00377.1"
                     /locus_tag="NRO40_RS01105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01105"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_058940768.1"
                     /transl_table=11
                     /translation="MSDTFTVAVTHHPYGTVVAVTGEMDLTTCPRVEEACTVLPVGGKT
                     LRLDLSGVSFMDSTGLNLLLRLRRRVQGDGSRMVLTGLQDQPRHLLDLTEAYSLFDTTG
                     AGEPAGRR"
     gene            2483..4879
                     /locus_tag="NRO40_RS01110"
                     /old_locus_tag="NRO40_01110"
     CDS             2483..4879
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947504.1"
                     /locus_tag="NRO40_RS01110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01110"
                     /product="hypothetical protein"
                     /protein_id="WP_257375304.1"
                     /transl_table=11
                     /translation="MRQPAGRGRLVLLCVFLVVLGGPWSRDVLLEWSTDHVGLELLRRA
                     LFVPGWQPEPGSHPFLRAYAWLGGLTLIGLIAGILLLVPRLVGRAPAGGVRWAASAGTG
                     VFLSVGSSTLAWLAVETVEPGLLLAFGQGGSFPVLFVDGLVFGVLLGLLIAVVGYGRAP
                     KAPGAVRPAASRNRERSAAVSDLPDDRPVAVATGTSPGDVTRYLCAAAYTDPAFADRVV
                     EDVLGDGLGAIAASPGVDLVPVARHSLTAGRLRRERDRRLTAAFGLVAVFAPLWLLFAR
                     LALGALGSASRTRRRAVRGRELPPTSATSWRLAGTAGALLVAGVLLGAALSAVPFPGPL
                     AWLTGGYLWGVPALLAVVACCALVVRTVVDEELDVDARLRGALRRDTFDPERLPRPGHL
                     EPWAAARIAAVADAQRGNVSCYSGHSPFVGYGRRDGEWTLSVPLLPADPGPGGERGPRT
                     VGGFDAWDVVERLRHRLRGAAQEPGAPLRGVGSGDRATGRAAAERDGAGGWDGAGGRDG
                     LGGRPGAEGRIEGLVVEDRVFVSGREVVRDGRLLPDPLRPPATRLPTEALRWIARRPDG
                     VARHFLASHVPLWGGEIVPTHFLHVAVEGRTLHLRCERFVLGPVRRDLHVVDLLPAGAP
                     TARRRRSLALRALRRSGGALWAAPRSCLSDALADRRRRVRRRHEARAAGDDPAYDRGAR
                     ISVREAAQGPEYFHHFQLVDALRTLNALDRHALAAVRDFLDDHGVDTTDFRTQTQTILN
                     HGVLQTGGVSVVGNQAVGTGAQATAKSTTARAGGPPPPSGPTATR"
     misc_feature    3038..3040
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4876..5301
                     /locus_tag="NRO40_RS01115"
                     /old_locus_tag="NRO40_01115"
     CDS             4876..5301
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385715.1"
                     /locus_tag="NRO40_RS01115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01115"
                     /product="DUF5955 family protein"
                     /protein_id="WP_058940767.1"
                     /transl_table=11
                     /translation="MTGGNVPRQADPSPGEPGEARVLNFGVQQYGGQSSVGNQAVGPGA
                     RAVAAHVSVQAPSADQRAEVEALLLLVERLLDEHRAALPDQESPRTELRRLREELDEGE
                     PEPGVVRRALERLALFAQPAAPLAAAVAELTRVVQSF"
     misc_feature    complement(5324..5339)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 24.0"
                     /tool="antismash"
     misc_feature    5345..5360
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.17"
                     /tool="antismash"
     gene            5469..6566
                     /locus_tag="NRO40_RS01120"
                     /old_locus_tag="NRO40_01120"
     CDS             5469..6566
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823141.1"
                     /locus_tag="NRO40_RS01120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01120"
                     /product="chitinase"
                     /protein_id="WP_257375305.1"
                     /transl_table=11
                     /translation="MPRHGRTSLALGLAAAVLAHLPAAALPAAARPAPVGAGAPAGGVP
                     APATCPLKPRPAGKVLQGYWENWDGAANGVHPPFGWTPITDPRIRPHGYNVVTTAFPVI
                     RSDGTALWENGMDTTVKVPTPAEMCEAKAAGLTVLLSIGGATAGIDLNSTAVADRFVAT
                     VVPILKAHNFDGIDIDIETGLVGSGDVTRPSPSQANLMRIIDGILERMPPGFGLTMAPE
                     TAYVTGGSVVYGSIWGAYLPLVKKYADNGRLWWLNMQYYNGSMYGCSGDSYEAGTVAGF
                     TAQTDCLDRGLVVQGTTIRVPYDRQVPGLPAQRGAGGGYMPPATVAQAWKAYGGRLKGL
                     MTWSLNWDGSRNWTFGDNVRALQGR"
     gene            complement(6646..7602)
                     /locus_tag="NRO40_RS01125"
                     /old_locus_tag="NRO40_01125"
     CDS             complement(6646..7602)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010472854.1"
                     /locus_tag="NRO40_RS01125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01125"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_058940765.1"
                     /transl_table=11
                     /translation="MHSEAPYAVRPATTGDASLICALLNEIDTIETGRPDTDLHSVEAD
                     LAHPEVDLARDSWLAFDGDRLVAYALVWDESQGERIDADHYVLPGHEAAGERLLAFAED
                     RAADRARANGASRAVLHLHLNAEPTTDLDMIARRGWRRVRRYHVMTRPLSAADQAAPEP
                     PAGVVLRDCRDDVDRQRAHALLQETFSEHFDHQPRTYAQWLDDIGGGDRIDWSLVWIAS
                     VGAEDAAVLFSRDDRKNMAWIGNIGVRRSFRGRGVAGHLLRHAFAVYAARGRDTIGLGV
                     DTQNETGALRVYEAHGMRTLHAVDTWEVVLPAGVAVA"
     misc_feature    complement(7634..7648)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.06"
                     /tool="antismash"
     misc_feature    7635..7646
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.72"
                     /tool="antismash"
     misc_feature    complement(8089..8103)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.09"
                     /tool="antismash"
     gene            complement(8143..9645)
                     /locus_tag="NRO40_RS01130"
                     /old_locus_tag="NRO40_01130"
     CDS             complement(8143..9645)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891136.1"
                     /locus_tag="NRO40_RS01130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01130"
                     /product="MFS transporter"
                     /protein_id="WP_058940764.1"
                     /transl_table=11
                     /translation="MREDGQALDGTVTTQIPARLDRLPWSRWHWMIVIGLGTVWILDGL
                     EVTIVGNMAGRLSEEGSGLAISSTQVTGVAAALYVAGACSGALLFGWLTDRYGRKKLFL
                     ITLAVYLGATAMTAFSYSSWWFFLFRFLTGMGIGGEYAAINSAIDELIPSKYRGRVDLV
                     INGSFWLGAMGGSLLSVVLLDTDILPKDIGWRVSFGLGVVLGLAVLLVRRHVPESPRWM
                     FIHGREEGAEAIVADAERRVERDTGKALAPPAGSITIKQRHSIGFAEIARTLVRTYPRR
                     AVLGFALFVGQAFLYNAITFGFGAILATFYDVPSGSTGYFFAVIALGNFLGPLTLGRLF
                     DTWGRRPMIAGTYLLSGALLFVTAWLFGQEVLTATTLTACWCVVLFFASAGASSAYLTV
                     SEIFPMETRAMAIAFFYAVGTAAGGISGPLIFAELTESGVVGDTVLAFCLGAAVMVVGG
                     LVALFFAVAAERKSLEEIATPLSAHAAGGTPDAPTEPVSLRP"
     misc_feature    9891..9908
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.14"
                     /tool="antismash"
     gene            10001..12598
                     /gene="lanKC"
                     /locus_tag="NRO40_RS01135"
                     /old_locus_tag="NRO40_01135"
     CDS             10001..12598
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016827685.1"
                     /locus_tag="NRO40_RS01135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01135"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_058940763.1"
                     /sec_met_domain="micKC (E-value: 8.8e-240, bitscore: 796.5,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 5.7e-11, bitscore: 40.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKGYATFCDADRHFYDAPHRLSAERQGGRGALYAAALTPVPEGW
                     RRNRSGDWLALRPVGAELPAQGWKIHVSACLENAETILARVSEYCLTHRIAFKFVPSRY
                     LLHTRNAKYADRAASGKFITVYPADDDQCHRVARDLDALLAGEDGPYILSDLRWGEGPV
                     YLRYGSFTQRHCYDEDGELRPAVEDPDGKLVPDLRGPVFRTPPWVRVPDFLRPHLADRH
                     AVTLADVPYTVERALHFSNGGGVYVGHDSRTGEKVVLKEARPHAGLAADGADAVTRLQR
                     EREALERLSGLPCTPEVRGGFELGGHHFLAMEYIEGKPLNTFFARRHPLIEADPTPESL
                     AEYTAWALRVHRMVEEAVAAVHARGVVFNDLHLFNIMLSEDESSVVLLDFEAAAHIDDN
                     RRQTVANPAFVAPADRRGFDVDRYALACLRIALFLPLTSLLPLDPEKARHLADVAAAQF
                     PVPRAFLDEAVAEILKGRPDAVGDGPYLPVEPGDWPRSRDSMARAVTASASPDREDRFF
                     PGDIAQFATAGGGLTLGYGAAGVLYALAETGAPAHPDAQEWLLRRVKEPPSGSPLGLYD
                     GLAGIAWALDRLGHPAPAADLAGLAMARPWEGVAPDLHSGLAGVGLALDALGHRDAALR
                     CAELVARALPGITRAGLLYGASGPALLFIRLYERTGDAALLDLAADALGRDLDRCVVSA
                     GGTLQVDEGWRTMPYLGAGSVGIGMVLDDFAAHRTDERFERARGEIVRAAQATFYAQPG
                     LFRGAAGMVLHLSRTTTPGPGTHPSDVRRQIDALARHAVPYQGHLAFPGEQMMRLSMDL
                     ATGTAGCLLALGSAATDGRAHLPFLPPLRRPQTRSQSGTAEEHTVPMKERNRS"
     gene            12595..12723
                     /locus_tag="NRO40_RS01140"
                     /old_locus_tag="NRO40_01140"
     CDS             12595..12723
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849360.1"
                     /locus_tag="NRO40_RS01140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01140"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_058940762.1"
                     /transl_table=11
                     /translation="MTLLDLQSMETPKEEATGDVATGSRASLLLCGDSSLSVTTCN"
     CDS_motif       12595..12660
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTLLDLQSMETPKEEATGDVAT"
                     /locus_tag="NRO40_RS01140_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12661..12723
                     /prepeptide="core"
                     /locus_tag="NRO40_RS01140_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="32.30"
                     /molecular_weight="1858.1"
                     /monoisotopic_mass="1856.9"
                     /core_sequence="GSRASLLLCGDSSLSVTTCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTLLDLQSMETPKEEATGDVAT"
                     /leader_location="[12594:12660](+)"
                     /alternative_weights="1876.1"
                     /alternative_weights="1894.1"
                     /alternative_weights="1912.1"
                     /alternative_weights="1930.2"
                     /alternative_weights="1948.2"
     gene            13050..15047
                     /locus_tag="NRO40_RS01145"
                     /old_locus_tag="NRO40_01145"
     CDS             13050..15047
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014180166.1"
                     /locus_tag="NRO40_RS01145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01145"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_079046832.1"
                     /transl_table=11
                     /translation="MPAARTPQTPPDPARTAADRVLRGALRHGAGHTAALLLCSLASAA
                     ATLAEPAVLGRTLDLLLAGDARAARWTALCAALITADLFLDAAVAQLTGVTNARTTRWL
                     RTRGVAGLLRAAPHDAARLPPGDLATRLTANAAEAGTVPAGAAAAAASVLPPLGGLVAL
                     FLIDWRTGAAFLAGVPALWLLLRAFATDSSDSVKHYQAAQSRIAARLVEALAGARTVAA
                     AGTAAHERRRVLGPLPEVAREGRRMWRVYGRAVARSGMLLPLLVCLVLAVGGLRLASGA
                     MGVGELLAVSRYAALAAGVGAVAGLLGALVHGRAAARRVAAPLALAPLPYGDGALPADG
                     PGTVELRGVSVVRDGTAVLRDVDVVLPGGARVAVVGRSGAGKSVFAAVAGRLTDPDAGE
                     VLLDGARLDALDEECLRREVGYAFARPALFGATVGDALAFGVDAPPGGALRAAARAADA
                     DGFVERLPAGYDTPVTRAPLSGGELQRLGLARAFAHAGRLLILDDATSSLDTVTERQVE
                     RALARDVRPGTRLVVAHRLSSATRADLVVWLEEGRVRAVGAHAVLWRDPEYRAVFAVRD
                     PSGGDGPAGGRGDADGEGHGSRPPTEGAGAGSGEVAGVVQVEGAGQIAGAPDVEGGAPS
                     GGAAEVSGAAPSEGAPGAGRAARAGRRAAR"
     gene            15044..17176
                     /locus_tag="NRO40_RS01150"
                     /old_locus_tag="NRO40_01150"
     CDS             15044..17176
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849358.1"
                     /locus_tag="NRO40_RS01150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01150"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_232790962.1"
                     /transl_table=11
                     /translation="MRGRGALRRLAPQARRFLLRRRRALLVLTGWSLLESVQTFLLGYG
                     VARALDDGFLAGRPATGLWWLSVAAGAALVGGLAMRGVFDGLAGLVEPLRDGLVRRAVA
                     QALASAVADPVRAGGASADGAAVSRLVHQTEMARDGFAGLVLAGRSFLFTALGALLGLA
                     SLAPALVLVVLPPLLLGLGLFLATLAPMAAAQRAFLDTDEALSARVGAVGAGLRDVVAC
                     GGRRLVAEEVGGLVVAEERLARRLARWAGVRTLALGAAGRLPVVALVVATPWLLARGVT
                     AGALLGALTYLVQSLLPAVHALMSALGAAGTRLVVVLDRFGTCEPTLPGDTPSPAPAGT
                     ADRAGTAPDAGPGAGPGAEPGTEADTKPGAETGAVVDAGPGTKPGTEADAVAAARPGAE
                     RGAETGTQPGTEADAGPGAGPGAKADAGPGAEPGGREPGTGAPPPAAAAAAGTPGGAPP
                     GAPAGYAERRARRGGRAAAVELRGVTFAYGPRARPVLDGLDLLVEPGEHLAVVGPSGMG
                     KSTLLAVLAGVLDPSRGTVLVAGSPARPAGAPGPDPRRALLPQEAYVFTGTVRDNLRYL
                     RPDAPPGDVGAAVEALRLGPLVRRLGGLDATVDPSALSQGERQHLALGRAHLSPAPLLL
                     LDEATCHLDPEAEEHAERTLAARPGTLVVVAHRLSSAVRADRVLVLDGTRSACAPHEAL
                     LEVSPLYRDLVGVSPV"
     gene            complement(17271..17879)
                     /locus_tag="NRO40_RS01155"
                     /old_locus_tag="NRO40_01155"
     CDS             complement(17271..17879)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142169.1"
                     /locus_tag="NRO40_RS01155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01155"
                     /product="response regulator transcription factor"
                     /protein_id="WP_198549264.1"
                     /transl_table=11
                     /translation="MTKVLVLHSVGLMRSALSALLRSEESFDVFDSGWRTARRSAESLR
                     PDVCVVDLDCPGAAGILEGGQEDGGTAFDARTRLLVLASAARPGALRKAFEARALGFVD
                     KNGSPRRLVRAIRAVARGERFVDESLAFGFLEASRMPLTARELSVLARAAEGDTIAEIA
                     RGLHLSNGTVRNYMASATRKVGARNRIDAIRISQGAGWV"
     misc_feature    complement(17748..17750)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18115..19053)
                     /locus_tag="NRO40_RS01160"
                     /old_locus_tag="NRO40_01160"
     CDS             complement(18115..19053)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NRO40_RS01160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NRO40_01160"
                     /product="hypothetical protein"
                     /protein_id="WP_058940761.1"
                     /transl_table=11
                     /translation="MGYDTSFHPVDLRLIEERLLPYLAGLGEDDAIDDLVAQAVETRKV
                     RFRAKAWALGLLAHARDRDDLPFDSHLHVWGRPFLIVGDGPERIAEDIRRYLATPVEGV
                     DALASEMVGRLDPALRDRVRPDEGGRLPADDVLAESLVGPLRVLRGAARALRAGERTVR
                     RPGDGRELDAAALVTREVPFNVLDFAAALLPGWMSRGHTWPTRLCADAGVPAEGFEAPT
                     ALTGLLRERFPALEWPPAPASITGNYTVGALVPASAVPGARSRLLTHRDRLDCEKRELR
                     KIDEAMGVAEVFGVAFCEATEIYSGLEGNLN"
     gene            19203..19967
                     /locus_tag="NRO40_RS01165"
                     /old_locus_tag="NRO40_01165"
     CDS             19203..19967
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (39-147). E-value: 5.4e-08. Score:
                     23.2. Matches aSDomain: nrpspksdomains_NRO40_RS01165_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010985317.1"
                     /locus_tag="NRO40_RS01165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01165"
                     /product="cyclopropane-fatty-acyl-phospholipid synthase
                     family protein"
                     /protein_id="WP_058940760.1"
                     /transl_table=11
                     /translation="MNAIDRLVRPDRYPRSSRYDPDWLLDLDMGPHPLWLLEDLARDLD
                     LRPGMRVLDLGSGKGATSVFLAREFGVEVVAADWWIGAEEATAVFAAAGVTDRVSAVHA
                     EAHVLPFEEGAFDAIVSIDAFEYFGTADGYLPYLARFLRPGGQLGVATPAMRHEVRELG
                     AIPAHVKALVGWEALAWHTPAWWRFQWEITELVTVTSARMQQDGWQDWLLWARACAAHR
                     PEGRSAHQPVIDMLIADGGEHLGFALVTARKH"
     aSDomain        19320..19643
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NRO40_RS01165_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="5.40E-08"
                     /label="NRO40_RS01165_oMT.1"
                     /locus_tag="NRO40_RS01165"
                     /protein_end="147"
                     /protein_start="39"
                     /score="23.2"
                     /tool="antismash"
                     /translation="LARDLDLRPGMRVLDLGSGKGATSVFLAREFGVEVVAADWWIGAE
                     EATAVFAAAGVTDRVSAVHAEAHVLPFEEGAFDAIVSIDAFEYFGTADGYLPYLARFLR
                     PGGQ"
     gene            20299..21024
                     /locus_tag="NRO40_RS01170"
                     /old_locus_tag="NRO40_01170"
     CDS             20299..21024
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122981.1"
                     /locus_tag="NRO40_RS01170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01170"
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="WP_058940759.1"
                     /transl_table=11
                     /translation="MADEGFTDPRLAALHDPLDPDRSDLDAYVRMVEEFGARRVVDIGC
                     GTGVFALLLAGAGVEVVGVDPAAASLDVARRKPGAAAVRWVLGDASDLPPVGADLATMT
                     ANAAQEVVGPEAWRRTLRGARAALRPGGRLVFETRDPAARAWEEWNREASYRVTEVPGT
                     GAVESWVEVTDVSLPLVTFRWTYRFAADGQVLTSDSTLRFRGRPEVEADLLAEGYVPLE
                     VRDAPDRPGREFVFVARRP"
     gene            21176..21571
                     /locus_tag="NRO40_RS01175"
                     /old_locus_tag="NRO40_01175"
     CDS             21176..21571
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003954042.1"
                     /locus_tag="NRO40_RS01175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01175"
                     /product="molybdopterin-binding protein"
                     /protein_id="WP_058940806.1"
                     /transl_table=11
                     /translation="MQSYTIGQAARLLGVSPDTVRRWADAGRVATHRDEAGRRLIDGRD
                     LAAFSIEVAQGGTEDEDTPYTSARNAFPGIVTAVKLGDVAAQVEIQAGPHRLVSLLTRE
                     AVEELGLEVGMRATARVKSTSVHIDRV"
     gene            21673..22494
                     /gene="modA"
                     /locus_tag="NRO40_RS01180"
                     /old_locus_tag="NRO40_01180"
     CDS             21673..22494
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0030973 - molybdate ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="modA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014050080.1"
                     /locus_tag="NRO40_RS01180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NRO40_01180"
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_058940758.1"
                     /transl_table=11
                     /translation="MSRTTTKRSVLRRRAAALLATVLLVPLASCGADGTGGEGPSAHGT
                     KGAKDAEDVRLTVLAAASLTDVFATAGDAYERSHPGTEVTFSFAGSQELVAQVRQGAPA
                     DVLVTADTKSMESVRGETGTPAVIARNRLVIAVAEGNPRGVDALEDLGDPKLKVVLAAP
                     EVPAGKYSAQVLDTQGVAVAPVSQEPNVRAVLSKVELGEADAGVVYRTDTESARDKVDA
                     VAVPDDRNAVASYPAATLKGSDDAGAAAAFVAWLSGPEAQRILRAAGFQQP"
ORIGIN
        1 acctgtcacc gcagtcggcg ctacccctgg tgcgacacca gccaccgccg ctccgcccca
       61 ccccgggaga cccgccagta ggccgcccgc cccggacgaa ccgcccgccc cgcccacccg
      121 gtggggcggg cgccgccgtg ttcggtgctc cccggcggcc gttccgcggt cactcggccc
      181 ctgatgccgc cggctcgggc tccgggggcc cgtcgcagaa gccggtccgg cagcagacgg
      241 gcaggaggtc ggggacggcc tcccggacgc gccgcagccg ggcccggtcg ggctccacca
      301 cggtgaggat ctcgaaggcg gtcccggcgt cccccacgca gcggcccgac accacctccc
      361 cgtacagcga ccacaggccc tgccgggtga tggtccggca ccgctccggc aggtcgaggc
      421 cgcgccgggc ggacacgggg tcggtgccct cacccgccac cgtgagctgc aggaggtcca
      481 ggaaccaagt gcgggccgcc ggcggaatcg tgtccgcgag ggcggcgagg gcgacagagg
      541 tcaccgcggg ggccggctcc cacagggtgg ccggggacca tacgtggccc tccaggagac
      601 cgtcggggcc gccgggggcg ggagtctccc gggcggactc caggaggtcc cgcgccaggt
      661 gggcggcgga ggcgccgcac ccgcacgtca tgcgctccca gtcgtggcgg gcagcctccg
      721 ccctgatcag tctcatggcc gcccacccta cggggccgcc ggagccccca ccgaacgcgt
      781 gtcgggggcc gcggccggac ggccgcggcc cccgacacgg gtggcgcgca cagcgctgct
      841 ggtggtgccg gcacgccgga gccgggcgtg ccgccgggac tcagatgcgg ccgcccgtca
      901 gacgggtgac cgggccgtgg gcgcgcagga cggacctgcg cccaccggcg taggcgccga
      961 cggccacggc tgtcgcggcc gccgcgacac cgccggcggt gacggcgttg gccttcagga
     1021 ggccgagcgc cggtacggcg gccttgcgcc acacgccgtt gaccgtcgac gtcagggcct
     1081 gggcctgggt ggcgagcacg cccccggtcg ccttgcccgc ctcgcccgcg ccgtcggtgg
     1141 cggcgcgggt cgtgtcgcgg gccgtccttc tggccgtgct ggtggcggtg cgggcccgcc
     1201 cgttcgcggc actggtgtcg gtggccgtgt ccttgccgct gctcttgttc ttgtccgttt
     1261 cactcatggg gtgcgcctaa cccgtcttca gccgcgaaaa ccggttcagg taaggcggct
     1321 tgaagtggac gggttcccgg gcgcccgccc cgctcgtggc tccggctgcc gactccgctc
     1381 gggcgccggt gagttgtccg ccctccggtg cgggcgggtg cgtccgaccc ggtgcgggcg
     1441 ggtgcgtgcg ggtgcgtgcg gcccggtgcg ggctcgccca aggcggtggt ggggaggagg
     1501 gtgtcgggcg ccgcacccgc gcgggcgtcg tcgccgtacg gggtctccgg cagggcgggc
     1561 cggtgtaccg gccgtcctcg gcgccaaagg caggtagccg cccggcgccg tggggaaggg
     1621 ggggtcgcgg gcggagtgcg tcgcgccacg cggggagggc cgcggaacgg acccgtgggg
     1681 gaagtcctgg ggagggcgag aggtggagtc gtgggaggga ggggcgtggg accgtcggtg
     1741 gggtggggtc agcgacggcc ggccggctcg ccggcgcccg tggtgtcgaa gagggagtac
     1801 gcctccgtga ggtcgagcag gtgcctcggc tggtcctgga ggccagtgag gaccatgcgg
     1861 ctcccgtcgc cctggacgcg acggcgcagc ctcagcagca ggttgaggcc ggtggagtcc
     1921 atgaaggaga cacccgacag gtcgaggcgc agcgtcttgc cgcccaccgg gaggacggtg
     1981 cacgcctcct cgacgcgggg gcaggtggtg aggtccatct cgcccgtgac ggcgacgacg
     2041 gtgccgtatg ggtggtgggt gacggcgacg gtgaaggtat cggacatggt tcgcccctct
     2101 cggggatcga gcccatgacg gccgcctcgg ggggcgcccg tcgagcgcgc ggcgtcgggc
     2161 cgcgcgcagc cgagcgagaa ccacccgtac cgtgaccggg ccaccgaccg tgaccccggg
     2221 acggcgcggg gttcccccgc cagaccaggc tggctcctgc cacagtgaca caccgcgagc
     2281 gcccggtgcc agtggctccc gcctccgtac gcgcgcgggg cggggcacgg ccggcgaccc
     2341 gtgcgcgggg gcgcgggacg gccgccgtgc gggcgccccg gggcgtgggc ggggcgcgtt
     2401 cccccaccgg tgtggtccgt tcggctgaca tgtggccgcc gacttcctag agttacgggt
     2461 ctcaggtgtt ccggggggtg ccatgagaca accggccggc agggggcgac tcgtcctcct
     2521 ctgtgtcttc ctggtggtgc tgggcggtcc gtggtcacgt gacgtactcc tcgaatggtc
     2581 gacggaccac gtcgggctgg agctgctgcg ccgggcactg ttcgtaccgg gatggcagcc
     2641 ggagcccggg tcgcacccct tcctgcgcgc ctacgcctgg ttgggcgggc tgacgctgat
     2701 cgggctgatc gccgggatcc tgctgctcgt cccccggctg gtgggccggg cgcccgcggg
     2761 cggtgtgcgg tgggcggcct ccgccggtac cggggtgttc ctctcggtgg gcagcagcac
     2821 gctggcctgg ctggccgtcg agaccgtcga gccgggcctc ctcctcgcct tcggccaggg
     2881 cggctccttc ccggtgctgt tcgtcgacgg gctggtcttc ggcgtgctgc tgggcctcct
     2941 catcgccgtc gtcgggtacg gccgggcccc gaaggccccg ggcgccgtgc gccccgcggc
     3001 gtcccgcaac cgtgaacgga gtgccgccgt gtccgactta cccgacgatc ggccggtggc
     3061 cgtcgcgacc ggcacgtcgc ccggcgacgt gacccgctac ctgtgcgccg ccgcgtacac
     3121 cgacccggcc ttcgccgacc gcgtcgtgga ggacgtgctg ggcgacgggc tcggcgccat
     3181 cgccgcctcg ccgggcgtcg acctggtgcc ggtggcgcgg cacagcctga ccgcgggcag
     3241 gctgcgccgc gagcgggacc gcaggctgac cgccgccttc ggtctcgtcg cggtgttcgc
     3301 ccccctgtgg ctgctgttcg cgcggctcgc cctgggggcg ctcgggtcgg cgtcgcggac
     3361 gcgtcggcgc gcggtgcggg ggcgggagct gccgcccacg tcggcgacgt cgtggcgact
     3421 tgccggtacg gcgggcgcgc tgctcgtcgc cggggtgctg ctgggcgccg ccctgtcggc
     3481 ggtccccttc cccgggccgc tggcctggct gaccggcggc tacctgtggg gggtccccgc
     3541 gctcctcgcc gtggtggcct gctgcgccct ggtggtgcgg accgtcgtgg acgaggagct
     3601 ggacgtggac gcgcgactgc ggggcgcgtt gcggcgcgac acgttcgacc cggagaggtt
     3661 gccgcgaccg gggcacctgg agccgtgggc ggccgcgcgg atcgcggccg tggccgacgc
     3721 ccagcggggc aacgtcagct gctacagcgg ccattcaccg ttcgtcgggt acggcaggcg
     3781 cgacggggag tggacgctgt cggtgccgct gctgcccgcc gacccgggtc cgggcgggga
     3841 gcgcggtccc cggaccgtcg gcggcttcga cgcctgggac gtcgtggagc ggctgcggca
     3901 ccggttgcgc ggggcggcac aggagccggg ggcgcccctg cggggcgtcg gaagcgggga
     3961 tcgggccacc ggacgggccg ccgcggaacg tgacggggcc ggtgggtggg acggcgcggg
     4021 cgggcgggac ggcctcggcg ggcggcccgg cgcggagggg cgcatcgagg ggctggtggt
     4081 ggaggaccgg gtgttcgtca gcggcaggga ggtcgtacgg gacgggcggc tgctgcccga
     4141 cccgctgcgg ccgcccgcca cgcggctgcc caccgaggcg ctgcggtgga tcgcgcggcg
     4201 cccggacggt gtcgcgcggc acttcctcgc ctcccacgta ccgctgtggg gcggggagat
     4261 cgtgccgacg cacttcctgc acgtggcggt ggagggtagg acgttgcacc tgcggtgcga
     4321 gcggttcgtc ctggggccgg tacggcgtga cctgcatgtg gtggacctgc tgccggcggg
     4381 cgcccccacc gcacggcggc gccgctcgtt ggcgctgcgg gcgctgcggc ggtcgggggg
     4441 cgcgctgtgg gcggcgccgc ggtcgtgcct gtcggacgcc ctcgccgacc ggcgcaggcg
     4501 ggtgcgtcgg cgccacgagg cgcgggccgc gggcgacgac cccgcgtacg accgcggcgc
     4561 gcggatcagc gtccgcgagg ccgcgcaggg gcccgagtac ttccaccact tccagctggt
     4621 cgacgccctg cggacgctga acgccctcga ccggcacgcg ctggcggccg tccgggactt
     4681 cctcgacgac cacggggtcg acacgaccga cttccggacc cagacccaga ccatcctcaa
     4741 ccacggcgtg ctgcagacgg gcggggtgag cgtggtcggg aaccaggccg tcggcaccgg
     4801 cgcccaggcg accgcgaagt cgaccacggc gcgggccggt ggcccgccgc cgccgtccgg
     4861 ccccacggcc acccgatgac aggagggaac gtgccccgtc aagccgatcc gtcgcccggc
     4921 gagccgggcg aggcccgcgt gctcaacttc ggcgtccagc agtacggggg gcagagctcc
     4981 gtcggcaacc aggcggtcgg tccgggcgcg cgcgccgtgg ccgcccatgt ctcggtgcag
     5041 gcgccgtcgg cggaccagcg ggccgaggtg gaggccctgc tgctgctcgt cgagcggttg
     5101 ctggacgagc accgggccgc gctgccggac caggagtcgc cccgtaccga actgcgccgg
     5161 ttgcgcgagg agctggacga gggagagccg gagccggggg tggtgcggcg ggccctggag
     5221 cggctggcgc tgttcgccca gcccgcggcg ccgctggcgg ccgccgtggc cgaactgacg
     5281 cgggtcgtgc agtccttctg acgccgctca cctcgtgcgg gcttctggtc cagacctctt
     5341 gacgaaaggt ctggaccaga agaccctggc cttccgtcga gtgccgtcga gcgcctgtcg
     5401 catccgtcgg gcgccgtcga gggtggcgcc cgggggacgt cgagggacgc cggggaagga
     5461 gcgcggacat gccgcgacac ggaaggacgt cactggctct ggggctcgcc gcggcggtcc
     5521 tcgcgcacct gccggccgcg gcgctccccg cggccgcccg gccggcgccc gtcggtgccg
     5581 gggcgcccgc cggcggggtg cccgccccgg cgacgtgccc gctcaagcca cggcccgccg
     5641 ggaaggtcct ccaggggtac tgggagaact gggacggcgc cgccaacggc gtccacccgc
     5701 ccttcggctg gaccccgatc accgacccgc gcatcaggcc gcacggctac aacgtcgtca
     5761 ccaccgcctt tcccgtgatc cggtcggacg gcacggcgct gtgggagaac ggcatggaca
     5821 ccaccgtgaa ggtgcccacg ccggccgaga tgtgcgaggc caaggcggcc gggctcaccg
     5881 tgctgctctc catcggcggc gccaccgcgg ggatcgacct gaactccacc gccgtcgcgg
     5941 accggttcgt cgccacggtc gtgcccatcc tgaaggccca caacttcgac ggcatcgaca
     6001 tcgacatcga gaccggcctc gtcggcagcg gcgacgtcac ccggccctcg ccctctcagg
     6061 ccaacctcat gcgcatcatc gacggcatcc tggaacgcat gcccccgggc ttcggactga
     6121 ccatggcccc ggagacggcc tacgtcaccg gcggaagcgt ggtctacggc tccatctggg
     6181 gcgcctatct gcccctcgtg aagaagtacg cggacaacgg ccgtctgtgg tggctgaaca
     6241 tgcagtacta caacggcagc atgtacgggt gctccggcga ctcctacgag gccggcacgg
     6301 tcgccggctt caccgcccag accgactgcc tggaccgggg gctcgtcgtg cagggcacca
     6361 ccatccgcgt cccgtacgac cggcaggtgc ccgggctgcc cgcgcagcgg ggagccggtg
     6421 gcggctacat gccgccggcc accgtcgccc aggcgtggaa ggcgtacggc ggccggctga
     6481 aggggctcat gacctggtcg ctcaactggg acgggtcacg gaactggacc ttcggcgaca
     6541 acgtccgggc cctccagggc cgctgacgga ccgccgggac cggcccggcc gagtgtctgc
     6601 ccggtacgcg cgcggggatc cgcccggcgc gggccgggcc ccgcctcagg cgacggccac
     6661 cccggccggg agcacgacct cccacgtgtc caccgcgtgg agcgtgcgca tgccgtgcgc
     6721 ctcgtagacg cgcagggcgc ccgtctcgtt ctgcgtgtcc acaccgaggc cgatcgtgtc
     6781 gcgcccccgc gccgcgtaga cggcgaacgc gtggcgcagc aggtgcccgg cgacgccccg
     6841 gccccggaac gaccggcgca ccccgatgtt gccgatccag gccatgttct tgcggtcgtc
     6901 gcgcgagaac agcacggcgg cgtcctcggc cccgaccgag gcgatccaca cgagcgacca
     6961 gtcgatgcgg tcaccgcccc cgatgtcgtc gagccactgc gcgtaggtgc ggggctggtg
     7021 gtcgaagtgc tccgagaacg tctcctggag cagggcgtgg gcgcgctgcc ggtccacgtc
     7081 gtcccggcag tcgcgcagca ccacaccggc gggcggctcg ggcgcggcct ggtcggcggc
     7141 ggagagcgga cgggtcatca cgtggtagcg ccgcacccgg cgccagcccc gacgggcgat
     7201 catgtcgagg tcggtggtgg gctcggcgtt gaggtgcagg tggagcaccg cgcgggacgc
     7261 gccgttggcg cgggcccggt ccgcggcgcg gtcctcggcg aacgcgagca gccgctcccc
     7321 ggcggcctcg tgaccgggca gcacgtagtg gtcggcgtcg atgcgctcgc cctgggactc
     7381 gtcccacacg agggcgtagg cgacgagccg gtcgccgtcg aaggcgagcc aggagtcccg
     7441 ggcgaggtcg acctcggggt gggcgaggtc cgcctcgacg gagtgcaggt ccgtgtcggg
     7501 cctgcccgtc tcgatcgtgt cgatctcgtt gagcagcgcg catatgagcg acgcgtcccc
     7561 ggtggtggcg gggcggacgg cgtagggggc ttccgaatgc atcaggccac tctcggaccg
     7621 tggccacgtc cccggcaaac gatttcccgc acccgacgcc cctcccccat gcccgatcgg
     7681 taccgaaccg ggagcgaggg ccaccggccg gcgtcacgcc tccgccaggg gcccgcagcg
     7741 cacaccggcg ggcgacgccg ttcacgggac gtcgtccggg ccactgcctc gtccgtgcgc
     7801 gcccgctcgt cgtcgtgcac ggggcccgtg cggtcggtca cgcgcgcggt cccgtaccgg
     7861 ggcacgaccc gtcggcggtg gtggcggccg ggatcccgac ccgggtgacg cggtccccgg
     7921 ccgccggtgc cgtgcacggc gttctcgaag gggagcatcg ccccggggag acggtccgac
     7981 gccctgctga cgggtgcgcg ccacgaagcg tgtcgagacg acggcgcgca cgtccgccgg
     8041 ggcggcggac gtgcgcgggg tgccgtcggc aggccgggcg ggtcgcacgg ggccggtcgg
     8101 ccggggccgc ggacgggggc gtgcgggcgg tggacgggag ggtcaggggc gcagggagac
     8161 gggctcggtg ggggcgtcgg gggtgccgcc ggcggcgtgg gccgacagcg gtgtcgcgat
     8221 ctcctccagg gacttgcgct ccgccgcgac ggcgaagaag agggcgacga gaccgcccac
     8281 gaccatcacg gccgcgccga ggcagaaggc cagcaccgtg tcgccgacca ccccgctctc
     8341 ggtgagctcg gcgaagatga gcgggccgga gatgccgccg gccgccgtgc cgaccgcgta
     8401 gaagaacgcg atggccatgg ctcgggtctc catcgggaag atctcgctga cggtcaggta
     8461 cgccgagctg gcgcccgccg aggcgaagaa gaggaccacg caccagcagg cggtgagcgt
     8521 cgtcgcggtc agcacctcct ggccgaagag ccacgcggtg acgaagagca gggcgcccga
     8581 cagcaggtac gtgccggcga tcatcgggcg gcggccccag gtgtcgaaga gccggcccag
     8641 cgtcaggggg ccgaggaagt tgccgagcgc gatcaccgcg aagaagtagc cggtcgaacc
     8701 gctcgggacg tcgtagaacg tcgcgaggat cgcgccgaag ccgaaggtga tggcgttgta
     8761 gaggaacgcc tgcccgacga agagggcgaa gccgaggacg gcgcgccggg ggtaggtgcg
     8821 taccagggtc cgggcgatct cggcgaagcc gatgctgtgc cgctgcttga tggtgatgga
     8881 gccggcgggc ggggcgagcg ccttgccggt gtcccgttcg acccgccgct cggcgtccgc
     8941 gacgatcgcc tcggcgccct cttcacggcc gtggatgaac atccagcgcg ggctctccgg
     9001 gacgtgccgc cggacgagca ggacggcgag gccgaggacg acgccgagcc cgaaggagac
     9061 gcgccagccg atgtccttgg ggaggatgtc ggtgtcgagg agcacgacgg acagcagcga
     9121 gccgcccatg gcgccgagcc agaagctgcc gttgatgacg aggtcgacgc ggccgcggta
     9181 cttgctgggg atgagctcgt cgatcgcgga gttgatggcc gcgtactcac cgccgatgcc
     9241 catgccggtg aggaagcgga agaggaagaa ccaccaggac gagtaggaga acgccgtcat
     9301 cgcggtggcg ccgaggtaga ccgcgagggt gatgaggaag agcttcttgc ggccgtagcg
     9361 gtcggtcagc cagccgaaga gcagggcgcc cgagcaggcg cccgccacgt acagggcggc
     9421 ggcgacaccg gtgacctggg tgctgctgat ggcgaggccg ctgccctcct cggacagccg
     9481 gcccgccatg ttgccgacga tggtgacctc gagcccgtcg aggatccaca cggtgccgag
     9541 cccgatgacg atcatccagt gccaccgcga ccacggcagc cggtccagcc gggcggggat
     9601 ctgcgtcgtg acggtcccgt ccagcgcctg cccgtcttct ctcatcgctt acctccacgg
     9661 cgtaaggggc cgcatccacg taccccatga tcaatccggg gaaacggggc ctcacccgtg
     9721 cggcctgacg ctccggggcg gggcgggagg gtcggagcgg acgggacggg caggccggag
     9781 cgcacggtac gggcggaggg gcccgggccg gtgggaacgg ggcccgcggt acggctgggg
     9841 ccgggtgtga ccagtagtgc ccgtggggcg tcggggtgct ggggcgcccg aggttactcg
     9901 tgcgttccgc acggctcatt gctgacagct gcgactgtcg gcggccctgt gccgggtggc
     9961 aacgttcttc ctgtcgccgt cgctgaccga aggagcaggt gtgatcaagg gatacgccac
    10021 cttctgcgac gcggaccgcc acttctacga cgcaccgcac cggctgtccg cggaacgcca
    10081 ggggggcagg ggtgcgctct acgcggcggc gctgacgccg gtgcccgagg gctggcggcg
    10141 caaccgcagc ggtgactggc tggcgctgcg cccggtcgga gcggaactgc cggcgcaggg
    10201 gtggaagatc cacgtgtcgg cctgcctgga gaacgcggaa acgattctgg cccgggtgtc
    10261 ggagtactgc ctcacccacc ggatcgcctt caagttcgtc ccgagccgct acctgctcca
    10321 cacccgcaac gccaagtacg ccgaccgcgc ggccagcggc aagttcatca ccgtctaccc
    10381 ggccgacgac gaccagtgcc accgcgtcgc ccgcgacctg gacgcgctcc tcgccggcga
    10441 ggacggcccg tacatcctca gcgacctgcg ttggggcgag ggcccggtgt acctcaggta
    10501 cggcagcttc acgcagcggc actgctacga cgaggacggc gagctgcgcc ccgccgtgga
    10561 ggacccggac gggaagctcg tccccgacct gcgggggccg gtcttccgga cgccgccctg
    10621 ggtgcgggtg ccggacttcc tccggccgca cctggcggac cgccacgccg tgaccctcgc
    10681 cgacgtgccg tacaccgtcg agcgggccct gcacttctcc aacggcggcg gcgtctacgt
    10741 cggccacgac tcccgcaccg gcgagaaggt cgtcctcaag gaggcccggc cgcacgccgg
    10801 gctggccgcc gacggcgccg acgccgtgac ccggctgcag cgggagcgcg aggccctgga
    10861 acggctctcc gggctcccct gcacgcccga ggtgcgcggc gggttcgaac tgggcggcca
    10921 ccacttcctc gcgatggagt acatcgaggg caagccgctc aacaccttct tcgcccgccg
    10981 ccacccgctg atcgaggcgg acccgacgcc ggagtccctc gccgagtaca ccgcgtgggc
    11041 cctgcgcgtc caccggatgg tggaggaggc cgtggcggcg gtccacgccc gcggcgtggt
    11101 cttcaacgac ctgcacctct tcaacatcat gctctccgag gacgagtcgt ccgtggtcct
    11161 gctcgacttc gaggcggccg cgcacatcga cgacaaccgc cgccagaccg tcgccaaccc
    11221 ggccttcgtg gcccccgccg accggcgcgg cttcgacgtc gaccggtacg ccctggcctg
    11281 tctgcgcatc gcgctcttcc tcccgctcac cagcctcctc ccgctggacc cggagaaggc
    11341 ccggcacctc gcggacgtgg ccgcggccca gttcccggta ccgcgcgcct tcctcgacga
    11401 ggcggtggcc gagatcctca aggggcggcc ggacgcggtc ggcgacgggc cgtacctgcc
    11461 ggtggaaccg ggtgactggc cccgcagccg cgactcgatg gcgcgggccg tgaccgcgtc
    11521 ggcgtcgccc gaccgggagg accgcttctt ccccggcgac atcgcccagt tcgccaccgc
    11581 gggcggcggg ttgacgctcg gctacggcgc cgcgggcgtg ctgtacgccc tggccgagac
    11641 gggcgcgccg gcccaccctg acgcgcagga atggctcctg cggcgggtca aggagccgcc
    11701 gtcgggcagc cccctcgggc tgtacgacgg cctggccggc atcgcctggg ccctggaccg
    11761 cctgggccat cccgccccgg ccgcggacct cgccggactg gcgatggccc gcccctggga
    11821 gggcgtcgcg cccgacctgc acagcggcct cgcgggggtc ggcctggccc tggacgccct
    11881 cggccaccgg gacgccgccc tgcgctgcgc ggaactcgtc gcccgcgcgc tgcccggcat
    11941 cacccgcgcc ggcctgctgt acggggcgtc cggacccgcg ctgctcttca tccgcctgta
    12001 tgaacgcacc ggcgacgccg ccctgttgga cctggccgcc gacgcgctcg gccgcgacct
    12061 ggaccgctgc gtcgtgagcg ccggcgggac actccaggtg gacgagggat ggcggaccat
    12121 gccgtacctg ggcgccggca gcgtgggcat cggcatggtg ctcgacgact tcgccgcgca
    12181 ccggaccgac gagcggttcg agcgggcgcg cggcgagatc gtccgggccg cacaggccac
    12241 gttctacgcc cagcccgggc tgttccgggg cgcggcgggc atggtcctgc acctgagccg
    12301 caccaccacc ccgggtcccg gcacccaccc ctcggacgta cgacgccaga tcgacgccct
    12361 ggcccgccac gcggtgccgt accagggaca tctggccttc cccggcgagc agatgatgcg
    12421 gttgtccatg gatctcgcca cgggcaccgc cggctgtctg ctggccctcg gcagcgccgc
    12481 gaccgacggc cgcgcgcacc tgccgttcct cccgccgctg cggcggcccc agacccggtc
    12541 ccagtcaggg accgcggaag agcacaccgt gcccatgaag gaaaggaatc gatcatgacg
    12601 cttctcgacc tgcagtcgat ggagaccccg aaggaagagg ccacgggcga cgtcgccacc
    12661 ggcagccggg ccagcctgct gctctgcggt gacagcagcc tcagcgtcac gacctgtaac
    12721 tgagccggtc ccggccggac cgcgcggtgt tcgcaccgcg cgggtcggcc ggcagcggct
    12781 gcggccccgg gcggtctcca tccgcccggg gccgcggccc tgctcccgcc cgccccggct
    12841 cgttctgccc ggacggggcc atcccggtac gacaggcgcg gggccgggtc ggtcatgggc
    12901 tcgtaccgac acgcacgaca cgcagaaccc gcacggcccg tgcggtaccc ctcggcgcac
    12961 acggcgctcg ccgcgcgcgg cccgtgcgcg ggacgctccg gccgccgtcc cgggcccgtg
    13021 ccggccggga gaggaaggag ccgcccacca tgcccgccgc gcgcaccccg cagacaccgc
    13081 cggatcccgc ccggaccgcc gcagaccgag tgctccgcgg agcgctccgg cacggcgccg
    13141 ggcacaccgc ggccctcctg ctctgctccc tcgcctccgc cgccgccacc ctcgccgagc
    13201 cggcggtcct gggccgcacc ctcgacctgc tgctcgccgg cgacgcacgg gcggcgcgct
    13261 ggaccgccct gtgcgcggcg ctcatcacgg ccgacctgtt cctcgacgcc gccgtcgccc
    13321 agctgaccgg cgtcaccaac gcccgtacga cgcgctggct gcgcacccgc ggcgtggcgg
    13381 ggctgctgcg ggccgcgccg cacgacgccg cccgcctccc gcccggtgac ctcgcgaccc
    13441 ggctgaccgc caacgccgcg gaggcgggaa ccgtgcccgc cggcgccgcg gcggccgccg
    13501 cttcggtcct gcctccgctg ggcgggctgg tcgccctgtt cctcatcgac tggcggaccg
    13561 gcgccgcgtt cctcgccggc gtcccggcgc tgtggctgct gctgcgcgcc ttcgccaccg
    13621 actcctccga cagcgtcaag cactaccagg cggcgcagtc gcggatcgcc gcgcgcctcg
    13681 tggaggccct cgccggggcg cggaccgtcg ccgccgccgg gacggccgcg cacgaacggc
    13741 ggcgcgttct cggcccgctg cccgaagtgg cccgcgaggg gcggcggatg tggcgggtgt
    13801 acggccgggc ggtggcccgc agcgggatgc tgctgccgct gctggtgtgc ctggtcctcg
    13861 ccgtgggcgg cctgcgcctg gcgtccgggg ccatgggcgt gggcgagctg ctcgccgtgt
    13921 cgcggtacgc ggcgctcgcg gcgggtgtgg gcgcggtggc cgggctgctg ggcgcgctgg
    13981 tccatggccg cgccgccgcc cggcgcgtgg ccgccccgct ggcgctggcg cccctgccgt
    14041 acggggacgg cgccctgccg gcggacggtc cgggcacggt ggagctgcgc ggcgtgtcgg
    14101 tggtgcgcga cggcaccgcc gtcctgcggg acgtggacgt cgtgctgccg ggaggggcgc
    14161 gggtggccgt cgtgggccgc tcgggcgcgg ggaaatccgt gttcgccgcc gtggcgggcc
    14221 ggctcaccga ccccgacgcg ggcgaggtgc tgctcgacgg agcgcgtctg gacgccctgg
    14281 acgaggagtg cctgcgcagg gaggtcgggt acgcgttcgc gcgcccggcg ctgttcggcg
    14341 cgacggtcgg cgacgccctg gcgttcgggg tggacgcgcc accgggtggg gcgctgcgcg
    14401 cggccgcgcg ggcggctgac gcggacggct tcgtcgaacg actgcccgcc gggtacgaca
    14461 cgcccgtcac gcgggcaccg ctgtccggcg gcgaactgca acgcctgggc ctggcccggg
    14521 cgttcgccca cgcgggccgg ctgctgatcc tggacgacgc cacgtcgagc ctggacacgg
    14581 tcactgagcg gcaggtcgag cgggcactgg cccgtgacgt gcgtcccggt acgcggctcg
    14641 tcgtcgcgca ccggctgtcc tccgccaccc gcgccgacct ggtggtgtgg ctggaggagg
    14701 ggcgcgtacg ggcggtgggt gcccatgcgg tgctgtggcg ggacccggag taccgcgcgg
    14761 tgttcgccgt acgggacccg tcgggcggtg acgggccggc cggggggcgc ggggacgcgg
    14821 acggggaggg gcacgggtcc cggcctccga cggagggggc gggagcgggg agcggagagg
    14881 tggcgggagt cgtgcaggtc gagggagccg ggcagatcgc gggtgccccc gacgtggagg
    14941 ggggcgctcc gtccgggggc gccgcggagg tgtccggcgc cgcgccgtcc gagggcgcgc
    15001 cgggggccgg ccgtgcggcg cgagcgggtc gccgggcggc ccggtgaggg ggcggggggc
    15061 gctgcgccgc ctcgcacccc aggcacgccg gttcctgctg cgccggcggc gggcgctcct
    15121 cgtcctgacc ggctggtccc tgctggagtc cgtgcagacc ttcctcctgg ggtacggggt
    15181 ggcccgcgcc ctggacgacg ggttcctcgc cggccgcccc gccaccgggc tgtggtggct
    15241 gtcggtcgcc gcgggcgcgg cgctggtcgg cggcctggcg atgcgcgggg tcttcgacgg
    15301 gctcgccggg ctcgtcgagc cgttgcgcga cggcctggtg cgccgggcgg tggcgcaggc
    15361 gctggcctcg gcggtcgccg acccggtgcg ggccggtggc gcgtccgcgg acggtgcggc
    15421 ggtgtcccgg ctcgtccacc agacggagat ggccagggac ggtttcgcgg ggctcgtcct
    15481 cgccgggcgg tcgttcctct tcaccgcgct cggcgcgctg ctgggcctgg cgtcgctcgc
    15541 gcccgcgctg gtgctggtcg tcctgccgcc gctgctgctg ggactggggc tgttcctcgc
    15601 gacgctcgcg ccgatggccg ccgcgcagcg cgccttcctg gacaccgacg aggcgctgtc
    15661 ggcccgggtc ggcgccgtgg gcgcggggct gcgggacgtg gtggcgtgcg gggggcggcg
    15721 gctggtcgcc gaggaggtgg gcgggctcgt cgtcgcggag gagcgcctgg cacgccggtt
    15781 ggcccgctgg gcgggcgtgc ggaccctggc cctcggcgcg gcggggaggc tgcccgtcgt
    15841 cgcgctggtg gtggcgacgc cgtggctgtt ggcgcggggg gtcacggcgg gcgcgctgct
    15901 gggggcgctc acgtacctcg tccagtcgct gttgccggcg gtgcacgcgc tgatgagcgc
    15961 cctgggcgcg gcggggacgc ggctggtggt ggtcctggac cggttcggca cctgcgagcc
    16021 gaccctgccg ggcgacaccc cgtcaccggc ccccgcgggc acggccgatc gcgccgggac
    16081 ggcacccgac gcggggccgg gcgcggggcc cggtgcggag ccaggcacgg aagccgacac
    16141 gaagccgggc gcggagaccg gcgcggtagt cgacgcgggg ccgggcacga agccgggcac
    16201 ggaagccgac gcggtagccg ccgcgaggcc gggcgcggag cgcggcgcgg agaccggcac
    16261 gcagccgggc acggaagccg acgcggggcc gggcgcgggg cccggggcga aagccgatgc
    16321 ggggcccggg gcggaacccg gtggccggga accgggcacc ggcgccccgc cacccgccgc
    16381 cgcagcggcc gccgggactc cgggtggggc gccccccgga gcgccggccg ggtacgccga
    16441 gcggcgggcc cggcgcggcg ggcgggccgc cgcggtcgaa ctgcgcggag tcaccttcgc
    16501 ctacggcccc cgggcgcggc cggtcctcga cggcctggac cttctggtgg agcccgggga
    16561 gcacctggcg gtcgtgggcc ccagcggcat gggcaagtcc acgctcctcg ccgtcctcgc
    16621 cggggtgctc gacccgtccc gcggcaccgt cctggtcgcc ggctccccgg cccgtccggc
    16681 cggggcgccg ggaccggacc cgcgccgcgc cctgctgccc caggaggcgt acgtcttcac
    16741 cgggaccgtc cgcgacaacc tccgctacct gcggcccgac gcgccgcccg gtgacgtcgg
    16801 ggcggcggtg gaggcgctgc gcctcggtcc gctggtgcgg cggctcggcg gcctggacgc
    16861 cacggtcgac ccgtccgccc tgtcgcaggg cgagcggcag cacctggcgc tcggccgggc
    16921 ccacctctcc cccgctcccc tcctcctcct ggacgaggcg acctgtcacc tcgacccgga
    16981 ggcggaggag cacgcggagc gcacgctcgc ggcacgtccc ggcacgctcg tcgtcgtggc
    17041 ccaccggctg tcgtcggcgg tacgggcgga tcgcgtgctg gtgctggacg ggacacggtc
    17101 ggcgtgcgcc ccgcacgagg ccctgctcga ggtctcgccc ctctaccgcg acctggtggg
    17161 tgtctccccg gtctgaagcg gcccggccgg tgtctcctcc cccgcctgac gccacccgaa
    17221 gggcgtccac cgggctcggg gccgccgggg ccggaacctc ccggcgccgg tcacacccat
    17281 cccgccccct gggatatccg tatcgcgtcg atgcggttgc gcgcgccgac cttgcgcgtg
    17341 gccgacgcca tgtagttgcg caccgtgccg ttcgacaggt gcaggcccct ggcgatctcg
    17401 gcgatcgtgt ccccctcggc cgccctggcg agcacgctca gctcgcgggc ggtcagcggc
    17461 atcctggacg cctccagaaa gccgaaggcg agcgattcgt cgacgaaccg ctcgccccgc
    17521 gccaccgcgc ggatggcccg cacgagccgg cgtggggacc cgttcttgtc cacgaacccc
    17581 agcgcccgtg cctcgaacgc cttccgcagc gcccccggtc tggccgcgga ggccagcacc
    17641 agcagtcgcg tgcgcgcgtc gaacgccgtt cccccgtcct cctgcccgcc ctccaggatg
    17701 cccgcggcac ccggacagtc gaggtccacc acgcacacgt ccgggcgtaa ggactccgcg
    17761 ctccggcgcg cggtgcgcca acccgaatcg aacacgtcga acgactcctc cgatctgagc
    17821 aatgccgaca acgcggaccg catcaggccg acgctgtgca gcacaaggac cttcgtcatg
    17881 gcggttcccc tcccggtgga cacccgaccg acgggccggg cgctggcaca cggcactgcc
    17941 gcgcgcatac cacccatgcg actgccccgc tgcgccgcgc gggaacatcg ctgtggggcg
    18001 tatgggggcg cgcgatatgg ccacgcgggc gcccctcatg caaatgtgcg ccctgtgtgc
    18061 gccccttacg tcaaccggcg tacgcgtgcc cgggatcacg cggcggacgc ggcgtcagtt
    18121 caggttgccc tccagcccgc tgtagatctc ggtcgcctcg cagaaggcga cgccgaacac
    18181 ctcggccacg cccatcgcct cgtcgatctt ccgcagctcg cgcttctcgc agtccagccg
    18241 gtcgcggtgg gtcaggagcc gggaccgcgc ccccggcacc gcggacgcgg gcacgagcgc
    18301 gcccaccgtg tagttcccgg tgatgctcgc gggcgcgggc ggccactcaa gggcggggaa
    18361 gcgctcccgc agcagcccgg tgagggccgt gggcgcctcg aagccctcgg ccgggacacc
    18421 cgcgtcggca cacagccggg tgggccaggt gtgaccgcgc gacatccagc cgggtagcag
    18481 cgccgcggcg aagtccagga cgttgaaggg gacctcgcgc gtcacgaggg ccgccgcgtc
    18541 gagctcccgc ccgtcccccg ggcggcgcac ggtgcgctcg cccgcgcgca gggcccgcgc
    18601 ggcgccgcgc aggacgcgca gcgggccgac cagcgactcg gcgagcacgt cgtcggcggg
    18661 gagccggccg ccctcgtcgg gtcggacgcg gtcgcgcagc gcggggtcga gccggcccac
    18721 catctccgag gcgagcgcgt ccaccccctc gaccggcgtc gccaggtacc ggcgtatgtc
    18781 ctccgcgatc cgttccggcc cgtcgccgac gatgaggaac gggcgccccc acacgtggag
    18841 atgggagtcg aagggcaggt cgtcgcggtc ccgggcgtgg gcgaggagac ccagggccca
    18901 cgccttggcg cggaagcgga ccttgcgcgt ctcgacggcc tgcgccacca ggtcgtcgat
    18961 ggcgtcgtcc tcccccagac cggcgaggta gggcagcagc cgctcctcga tcagccggag
    19021 gtcgacgggg tggaagctcg tgtcgtaacc catgatcggc aacctaacgc cggccactga
    19081 caaggaccgg cgcggggtgg ggccgtacct gtgggcgagg ccgtacgggc gggtgccccg
    19141 ccaccgtagg tgcggggaaa gccggttgtc ctcccccggg cgatgcgctt gggtgtccga
    19201 tcatgaacgc gatcgaccgt ctcgtacgcc cggaccgcta cccgcgctcc tcccggtacg
    19261 accccgactg gctgctcgac ctcgacatgg ggccgcaccc gctgtggttg ctggaggacc
    19321 tcgccaggga cctcgacctg cgtccgggca tgcgggtcct cgacctcggc tcgggcaagg
    19381 gcgccacctc ggtcttcctc gcccgcgagt tcggcgtgga ggtggtggcc gcggactggt
    19441 ggatcggcgc cgaggaggcg acggccgtct tcgccgcggc cggcgtcacc gaccgcgtct
    19501 ccgcggtaca cgccgaggcc cacgtcctgc cgttcgagga gggggccttc gacgcgatcg
    19561 tgagcatcga cgcgttcgag tacttcggca cggcggacgg ctacctgccc tacctcgcgc
    19621 ggttcctgcg cccgggcggt cagctcggcg tcgccacccc ggcgatgcgc cacgaggtcc
    19681 gcgaactcgg ggcgatcccg gcgcacgtga aggcgctcgt cggctgggag gccctcgcct
    19741 ggcacacccc cgcgtggtgg cgcttccagt gggagatcac cgaactcgtg acggtcacct
    19801 cggcccgcat gcagcaggac ggctggcagg actggctgct gtgggcgcgg gcctgcgccg
    19861 cgcaccggcc ggaggggcgg tccgcgcacc agccggtgat cgacatgctc atcgcggacg
    19921 gaggggaaca cctgggcttc gccctggtga ccgcgcggaa gcactgaccc ggtgccccgc
    19981 ccccgacgcc cggccgcagt cccacggccc ggccccggga ccgggcccgt ggctggggga
    20041 ccggcccgcg ggaacggcag ggggcgccgc tcagccggag gacaggtgac gctcggggaa
    20101 gcggctcacg tgctgccgga ccagggagac cgcgcggccc gggccgaggg agcccgccat
    20161 ccccgcccgt ccccccgccg tcatcgaccc ctgcgcgaac cccgccagca cgtctggggc
    20221 cgtcctcggt gcgctcggtc ggtcgggccg gtcgggccgg tcgggccggt cgggccgagg
    20281 ctccgtagcc tgcgtcatat ggctgacgaa ggcttcacgg acccgcggct cgccgcgctc
    20341 cacgacccgc tcgaccccga ccggagcgac ctcgacgcct acgtgcgcat ggtcgaggag
    20401 ttcggtgccc gccgcgtagt ggacatcggg tgcggcacgg gggtgttcgc cctgctcctg
    20461 gcgggcgcgg gcgtggaggt ggtcggggtc gacccggccg ccgcctcgct cgacgtggcc
    20521 cgccgcaagc cgggggccgc ggcggtgcgg tgggtcctcg gcgacgcgtc ggacctgccg
    20581 cccgtggggg ccgacctcgc cacgatgacg gcgaacgccg cccaggaggt ggtcggtccg
    20641 gaggcgtggc ggcggaccct gcggggtgcc cgcgcggcgc tgcggccggg cggccggctc
    20701 gtgttcgaga cgcgcgatcc ggcggcacgc gcctgggagg agtggaaccg ggaggcgtcg
    20761 taccgcgtga cggaggtgcc gggcaccggc gccgtcgaga gctgggtcga ggtgaccgac
    20821 gtgagcctgc ccctggtgac gttccgctgg acctaccgct tcgccgccga cgggcaggtc
    20881 ctcacctcgg actcgacgct gcggttccgc gggcgcccgg aggtcgaggc ggacctgctc
    20941 gccgaggggt acgtgccgct cgaggtgcgc gacgcccccg accggcccgg ccgcgagttc
    21001 gtcttcgtgg cccggcggcc ctgaaccggc gccaccgcgg cctcccctgc ccctcgcaca
    21061 ccccgccccc cgcccccggc acgccttcgg tgcttcctcc aagcaaaccg cagatgccat
    21121 ggagaaagcc gacaatcctt gcaggtgcgg cccacagggg cctagcgtgg cgcacatgca
    21181 gtcctacact atcggtcagg ccgcgcggct cctcggggtg agccccgaca ccgtgcggcg
    21241 ctgggcggac gccggccggg tcgcgaccca ccgtgacgag gcgggccgcc gcctcatcga
    21301 cggacgcgac ctggcggcct tctcgatcga ggtcgcccag ggcggaacgg aggacgagga
    21361 caccccgtac acctccgccc gcaacgcctt ccccggcatc gtcaccgcgg tcaagctcgg
    21421 tgacgtcgcg gcccaggtcg agatccaggc cgggccgcac cggctcgtct ccctgctcac
    21481 gcgggaggcc gtcgaggagc tggggctgga agtcggcatg cgggccaccg cccgtgtgaa
    21541 gtcgaccagc gtgcacatcg accgcgtctg accgcgcgcc cgcacggcga agccgcccgt
    21601 cccccgcacg gccctccgcc cgcgcaccgg cggccccgcc cgtgcgcacg ccacacaccg
    21661 gagtccatcg ccatgtcccg caccaccacc aagcggtccg tcctgcggcg ccgcgccgcg
    21721 gccctcctcg ccaccgtcct gctcgtgccg ctcgcctcct gcggcgcgga cgggaccggc
    21781 ggtgagggcc cgtccgcgca cggcacgaag ggcgcgaagg acgccgagga cgtgcggctc
    21841 accgtcctgg ccgccgcgtc cctcaccgac gtcttcgcca cggccggcga cgcgtacgag
    21901 cgctcccacc cggggacgga ggtcaccttc tccttcgccg gctcccagga gctcgtcgcg
    21961 caggtccggc agggcgcccc cgccgacgtg ctggtcaccg ccgacaccaa gagcatggag
    22021 agcgtgcggg gcgagaccgg tacccccgcc gtcatcgcga ggaaccgcct cgtcatcgcc
    22081 gtcgccgagg gcaacccccg gggcgtcgac gcgctggagg acctcggcga cccgaagctg
    22141 aaggtggtcc tcgccgcgcc ggaggtaccc gccgggaagt acagcgcgca ggtcctcgac
    22201 acacaaggcg tcgccgtggc cccggtctcc caggagccga acgtccgcgc cgtcctgagc
    22261 aaggtcgagc tcggcgaggc cgacgccggg gtggtctacc ggaccgacac cgagagcgcc
    22321 cgcgacaagg tcgacgcggt cgccgtcccc gacgaccgga acgccgtcgc ctcctacccg
    22381 gcggcgaccc tgaagggctc cgacgacgcg ggggccgccg ccgcgttcgt ggcgtggctg
    22441 tccgggccgg aggcacagcg catcctccgg gccgccggct tccagcagcc ctgaccctcg
    22501 gggccgcctc gccgagcggg tccgcgggac actcccggca gccccggccc ggcggccacc
    22561 gcccgacagc ccccggccgc ggccaccgcc cggccccg
//
