LOCUS       NZ_CP085682            25388 bp    DNA     circular CON 22-AUG-2024
DEFINITION  Paenibacillus polymyxa strain YS18-2 chromosome, complete genome.
ACCESSION   NZ_CP085682
VERSION     NZ_CP085682.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5840603)
  AUTHORS   Liu,J. and Huang,Y.
  TITLE     Complete Genome Sequencing of Paenibacillus polymyxa strain YS18-2
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5840603)
  AUTHORS   Liu,J. and Huang,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-OCT-2021) Department of Sericulture, South China
            Agriculture University, Wushan, Guangzhou, Guangdong 510642, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. v.3.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 253.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024584565.1-RS_2024_08_22
            Annotation Date                   :: 08/22/2024 06:09:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,167
            CDSs (total)                      :: 5,043
            Genes (coding)                    :: 4,970
            CDSs (with protein)               :: 4,970
            Genes (RNA)                       :: 124
            rRNAs                             :: 13, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 13, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 40 of 73
            Pseudo Genes (incomplete)         :: 41 of 73
            Pseudo Genes (internal stop)      :: 12 of 73
            Pseudo Genes (multiple problems)  :: 18 of 73
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:38:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4412626
            Orig. end                         :: 4438014
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP085682.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25388
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="17"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..25388
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25388
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15388](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15388)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     gene            935..1975
                     /locus_tag="LJR53_RS19050"
     CDS             935..1975
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688423.1"
                     /locus_tag="LJR53_RS19050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_123797565.1"
                     /transl_table=11
                     /translation="MNIKTIASMAGVSVATVSKIINNYTDISEETRQRVLKIMEETGYR
                     PSSSAKTLATKKSNLVGVIFAGKLNVDFSHPFFVDIINVFKKQIGLLGYDLLFFSNEKF
                     LDNGEDYLARSKYFSVDGCIIIAGDEVEKSVFDLDASPIPCIGVDIELTGASSCYIMSD
                     NQKISMKVVEHFYMNGYREMGFIGIERPSLVIKEREEAFISSLKRFSLDVRPEWIVYGK
                     DYAAEDGYQIAKAWIQQENLPRAIFAATDLLAFGAIRAFKESGLKVPEDIAVVGCDDIE
                     ACRYTDPPLTTVKQDKQKIGRLAAMVLFDLMNKQMDTKCIKVEPELVIRTSCGARQHWN
                     PTRVEG"
     gene            complement(2060..3553)
                     /gene="glpK"
                     /locus_tag="LJR53_RS19055"
     CDS             complement(2060..3553)
                     /EC_number="2.7.1.30"
                     /GO_function="GO:0004370 - glycerol kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="glpK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210: glycerol kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818622.1"
                     /locus_tag="LJR53_RS19055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycerol kinase GlpK"
                     /protein_id="WP_025365661.1"
                     /transl_table=11
                     /translation="MGKYILSLDQGTTSSRAILFNSEGDVVYSAQREFPQYFPHPGWVE
                     QNANEIWSSILGVIASCLSESGVKAKQIAAIGITNQRESVAVWDKNTGLPVYNVLVWQS
                     RQTSDICEELKRQGHEELFHSKTGLLIDPYFSGTKVKWILDHVEGAREKAERGDLLFGT
                     IDSWLIWKLSGGKAHVTDYSNAARTLMYNIYELKWDEELLDILGVPKIMLPEVRPSSEV
                     YAHTVDYHFFGQNVPIAGAAGDQQAALFGQACYEKGMIKNTYGTGCFMLMNTGDQPVES
                     KHGLITTIAWGLEEGKVQYALEGSVFVAGSAIQWLRDGLRMFREAKDSEPYAARVSSTE
                     GVYLVPAFVGLGSPYWDSEVRGAMFGLTRGTTKEHFIRATLESLAYQTKDVLTAMEIDS
                     GITVKMLRVDGGAVLNNFLMQFQSDILDATVERPVIHETTALGAACLAGLAIGYWKSTD
                     ELRKRVRVETSFTPTMDEATRDSLYEGWKKAVNATMAYK"
     gene            complement(3585..4409)
                     /locus_tag="LJR53_RS19060"
     CDS             complement(3585..4409)
                     /GO_function="GO:0015267 - channel activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688424.1"
                     /locus_tag="LJR53_RS19060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MIP/aquaporin family protein"
                     /protein_id="WP_019688424.1"
                     /transl_table=11
                     /translation="MSPYAAEFIGTMILIALGGGVCAGVSLKKSFAHASGWIVVGLGWG
                     LAVAIGVYAVGQISGAHLNPAVTLALAFQGSFPWQDVPGYIVAQVLGAMAGAVIVILHY
                     WPHWKETEDTAAKLSVFATGPAIDHPFGNVLSEMIGTFIFVLALLSFGANSFTDGLKPL
                     IVGFLVVSIGLSLGGTTGYAINPARDFGPRLMHYLLPIPGKGASNWKYAWVPIVGPLLG
                     GSFAGPFYQAVFKGSMTPAFWILLGVIVVVLLITFRISRIYKNHKMDHKLTA"
     misc_feature    4365..4380
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.4"
                     /tool="antismash"
     gene            4728..6209
                     /locus_tag="LJR53_RS19065"
     CDS             4728..6209
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372703.1"
                     /locus_tag="LJR53_RS19065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PTS transporter subunit EIIC"
                     /protein_id="WP_025365662.1"
                     /transl_table=11
                     /translation="MLKFLQKIGKSLMLPVATLPAAGILQGLALINYETDIPLGPGVGG
                     FLNHYVTPFLNEGAGAIFGNLALIFSIGVAIGLAGDAVAALSAVIAYLVLTRILAAVPG
                     IFAYIPDDVKLDMGVLGGIFIGGWSAYLFKKYHNIQLPDWLGFFSGKRFVPMITAFTTM
                     ILAILLGMIWSPIQDGIAAFGNWIVGFGGIGSMVFMIANRLLIPLGLHHVLNSIAWFQI
                     GNYTNAAGEVVHGDLTRFFAGDTSAGMFMSGFFPIMMFALPAAALAFIHTAKPEKRKAV
                     ASIFIGSALASFLTGITEPLEFSFMFIAPLLYGIHALLTGLSGLVVYLLDVKLGFSFSA
                     GLIDYLVNMKLSTHPLRMIPIGLVFALIYYFLFRFIILKFNLKTPGREDDVDDTLLFEA
                     NKSIPVGKASASSGTQSSQAGQVLTYLGGSDNIQSIDACITRLRLVVKDDKAVNDQALK
                     QLGASGIIRLGNGTLQVIFGTRSEALKDEIQRLMS"
     gene            6407..7696
                     /locus_tag="LJR53_RS19070"
     CDS             6407..7696
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014277625.1"
                     /locus_tag="LJR53_RS19070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_025365663.1"
                     /transl_table=11
                     /translation="MKTVQWQWLVLCLAFLTMISGCSGSLSSKGQSSEANLSNSKKITL
                     TLWYWNRSIDDELLVQAEKQFPNIELKTQKIGGDFKAKLKTTLAARSGEPDIVALNDWM
                     VELFPSADRFYDLKELGADRLKDQYLEWKWNQGITPDGKMIAFPMDTGPTALFYRSDLF
                     EQAGLPSDPEQVSASIRTWDDYMAAGEQLRQKFGSHSFLADNIVNVYNQVLAQHTNLYF
                     KPDGSYIGNQSPDIRLGWKTAVNFHRKHLLANADGWTPEWNASVNNGKIASFVGAIWMK
                     QVLTEAAPDTAGKWRVARAPGGDGNLGGSFISILKSSQHPKEAFEVLTWLQSPEHQLEA
                     YHKIGLFPSTPGVYDDPVMETPEPFFGGQATGLIFAASARQVKNSYFGERYPVIHGIVT
                     RRLANVAKQNADPEALWTETMQRIERELQR"
     gene            7730..8605
                     /locus_tag="LJR53_RS19075"
     CDS             7730..8605
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014277626.1"
                     /locus_tag="LJR53_RS19075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_016818618.1"
                     /transl_table=11
                     /translation="MLREIWKHRAVYAAISPFYLLFGIFGLFPIGFSLYLAFHKWDGIG
                     DMTYNGWGNFRYLVTDNEFWQAVGNTFVIWVYATIPMLFLALIVAFLLYAPFVKMRTLW
                     RVGFFLPNVTSIVAVAIIFGALFANNFGFLNYLLQLLGLPMIQWLNVPWGIQIAISSMV
                     VWRWMGYNAIIYLAGLQSIPHVLYEAAKIDGATGAQAFFRITIPMLRPVILFTVITSTI
                     GGMQLFTEPQVLVGNDGGAGASGMTIVLYLYRESFINNYFGYGAAVGWGMFLIIALFSI
                     INWKLVQGKK"
     gene            8627..9454
                     /locus_tag="LJR53_RS19080"
     CDS             8627..9454
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372706.1"
                     /locus_tag="LJR53_RS19080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_025365664.1"
                     /transl_table=11
                     /translation="MMQTRAKSIVLYAGLLVGIILSMFPFYWLIVMATRTTSDIYRFPP
                     QLWFGSHFLDNITRVLQQIDFAGAFLNTLFVASSITLLVLFFDSLAGFAFAKFDFPGKK
                     ALFVILLATMMVPSQLSLVPSFVMMASFGWVGTFKALIIPGMVNAFGIFWIRQYAEESI
                     PKELLDSGRMDGCSFFRLYWNVALPILRPAFAFLGAFTFIGAWNDYLWPLIVLTDERKF
                     TLQIALSQLNGIYNTDYAMVIAGTLLAVLPLIILFLFISRQFISDLAAGAIKD"
     gene            complement(10001..11533)
                     /locus_tag="LJR53_RS19085"
     CDS             complement(10001..11533)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372709.1"
                     /locus_tag="LJR53_RS19085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_025365665.1"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     2.9e-07, bitscore: 28.8, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 2.5e-46, bitscore:
                     156.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5.8e-06, bitscore: 24.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILDSTVMEFFRNIKKQYGNYSRLFKLFQTKNKSYLYDVGTGKVM
                     ECTEIEYVFLNNLQVYGDIEEVIKPTKVNDDTLTILIDLIHVAQEQHLFQAPPLLSFAL
                     SKDEVLENARSHLEQVTLELTEQCNMACHYCIYHSGNIDFREFGRRHMSWQVAELAIDY
                     TLKNSGKKVAVTFYGGEPLIEFKLLKHCVDYTLKNGADKDLTFSMTTNLTLMTAEIAEY
                     LSTVPNFGVVCSIDGPKEIHDCRRVFKNGEGTYVKAINGLKHLINAYGEKSNSLISLSM
                     VTPRPANDVVMKKIQNFFNSLSWVPKDITKNISYVRHSSDIEKTITEKSSMHCYDNPVG
                     NWTIDLMLNNTSISKNTPFTIDFLHKQFSIIHDRILTETPYPDYCLNGCCSPASRRIYV
                     TVNGDFHLCERIGKSPSVGNVYSGIDESVLIDRYIDDYGKESLSQCSKCWAIRLCSVCY
                     VECYDSDKFNIEKKRIACRRSLDMLEHALISYHTILEHKPHLLEELNHITLV"
     aSDomain        complement(11288..11518)
                     /aSDomain="Other_Sactipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a sactipeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_LJR53_RS19085_Other_Sactipeptide_rSAM
                     _RRE.1"
                     /evalue="1.60E-09"
                     /identifier="RREFam021.1"
                     /label="LJR53_RS19085"
                     /locus_tag="LJR53_RS19085"
                     /protein_end="82"
                     /protein_start="5"
                     /score="28.8"
                     /tool="antismash"
                     /translation="TVMEFFRNIKKQYGNYSRLFKLFQTKNKSYLYDVGTGKVMECTEI
                     EYVFLNNLQVYGDIEEVIKPTKVNDDTLTILI"
     gene            complement(11499..13178)
                     /locus_tag="LJR53_RS19090"
     CDS             complement(11499..13178)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818615.1"
                     /locus_tag="LJR53_RS19090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_306459337.1"
                     /transl_table=11
                     /translation="MNMIVLEYLKKYLSKTRKYVFFYIVVTSVLWIIGIIVPYITGIYI
                     DYLVSKSNISIILYFVLLLGIINIVNILIQYLTALFSTKLNNLLLYEICNDIYQKIFKT
                     KLSVFKDKDNAYLVDQINNDSSTVVDFFSNNISNLVLQVITIIISGIIVLKADVLLCVI
                     IFSLIPFYIFTYVVFRKKLYKANLKYKKEANEYYSKKVEQINKLVFIKKNVLFNEMNER
                     LNKAFNSLFRVATSQVKTNYIFSNLNQFILIICYIFVIGIGGHKVVIGQMSIGQFTIIN
                     TYLSMIISSTSYLLSLASSYQETKVSIERLNDVMNSENDIYGSTTLEDLEKISIKQLGV
                     KYSEESVFRDFSYDFFKGGIYGICGHNGSGKTTLLNTLIGLYSDLYTGEIAFNNCSIKD
                     IDMLDMRRYRISYVEQNPEFLNLPIKEYLKFGITFSKEIASNQDELITAFGLEEIITKA
                     NLENILINENGSNFSGGEKQKLALIRALSKDSFLTILDEPTSALDSKSVSGLIEILTKQ
                     KSRRITIVVSHDQRLLAACDHILNIETQEERDDIGFHSYGVL"
     gene            complement(13419..14066)
                     /locus_tag="LJR53_RS19095"
     CDS             complement(13419..14066)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818614.1"
                     /locus_tag="LJR53_RS19095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_017427401.1"
                     /transl_table=11
                     /translation="MLMLKKMCIVLCGFLLMGMPLGASSNAASNDVKNINLTAINCNVT
                     VTKTSASDFSYEYNKSLYTVTSTLSGSTIYITVKGKGSANGISDRVNILIPDKSYEKIT
                     VESTKSGVSLPELNTNLDITGVDGSSMSVRVPVGYSKAISYDNTKGSGSLTFSKGASDY
                     TVTVKTTASALSVPAGWPLFRPNLTYNYINGAGKAKINITLENSAFSIAAQK"
     gene            complement(14060..15388)
                     /locus_tag="LJR53_RS19100"
     CDS             complement(14060..15388)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372712.1"
                     /locus_tag="LJR53_RS19100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="WP_025365666.1"
                     /sec_met_domain="PTHR43273 (E-value: 1.3e-39, bitscore:
                     134.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3.7e-14, bitscore: 51.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3e-10, bitscore: 38.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.5e-16, bitscore:
                     57.2, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKASQYNFIFNDIIENTDKTVLYNSRTGALAVLEPEYYKQFCELT
                     NNELAINNDTYLKNLIECGYIVEDNMNEKAYVKVNLLKNRFESSNLMLTIAPTMACNFR
                     CVYCFEKDQYHNKTMSQETAQSIVNFVKTNASKLDTLNVTWYGGEPLIAMKQIVRISED
                     FLEICKENNIQYTASVITNGYLLNKEKVQTLISCGVNDIQVTVDGPKEVHDLRRPLVSG
                     RGTFDVIMNNLKQIKGMIKIFMRINTDQDNWLKLHEIVGFLKENSLLENVIPYLGLVTP
                     TNGKYEGTKCLTDEMYSKFNLKFMSENDIPISYIYPAPKGNYCSADKYNSFVIDPLGHL
                     YKCWSDIGIIEQCVGNINEDTSVKWNTELLGCYLLYDPTEDEKCSDCKYLPVCLGGCPH
                     NRMADFNICEQYRYNLQEYITECTKVLLAGQLTGNKKEVSESC"
     misc_feature    complement(15443..15458)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     misc_feature    15796..15813
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.33"
                     /tool="antismash"
     gene            16154..16909
                     /locus_tag="LJR53_RS19105"
     CDS             16154..16909
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818612.1"
                     /locus_tag="LJR53_RS19105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_225164799.1"
                     /transl_table=11
                     /translation="MVYLFQVAVCDDDPAMHKILQHFFMCMSVSESLDFNLQFFLSGED
                     LIKSYSSQERYPFHIILLDIEMRELSGIETAKLIRLFPDREVQIIFLTNYPEYMLESFE
                     VQAFQYLLKPLTYKLFVEKINKLCHYMRSSVSHFLSVKNKTEHLVLRHSEIIVISKGEN
                     NYIHNELCIATDSHNYFISGTLKAVYEQLKYPFVFIHRSIIVNLVHIRKFSATSVIMSN
                     EQEFPVGRSHAKSLREAYARFIISRFQEG"
     gene            17308..17928
                     /locus_tag="LJR53_RS19110"
     CDS             17308..17928
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372715.1"
                     /locus_tag="LJR53_RS19110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase"
                     /protein_id="WP_225164800.1"
                     /transl_table=11
                     /translation="MQEKRYKETTRSLSDIKRSIHDFKKQLIFVRACLQEQRTEEGVNH
                     INQTLKNIDSPKLHITTGHLVIDALVNHTFSIANKSGIAFFHQIHINPANISIGSHDLC
                     IVLGNVFDNAIEAVMQLPRKKEHSIHLEIFTDNIALWIYVRNSKSNYLNTAFSTKTYNP
                     PLKKHGYGLLNIQQVIKKYGGYLNTTITDSHFQITIMLPCNNS"
     gene            complement(18054..19472)
                     /locus_tag="LJR53_RS19115"
     CDS             complement(18054..19472)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1153: Amino acid carrier protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007431746.1"
                     /locus_tag="LJR53_RS19115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sodium:alanine symporter family protein"
                     /protein_id="WP_039269192.1"
                     /transl_table=11
                     /translation="MNLVHVLETISSWIWGAPLIILVMGTGLWLTIRLKMLQVFRLPLA
                     IKLIGKAPNEGSGDVSSFAALSTALAATVGTGSIVGVATAIKLGGPGALFWMVVAAFFG
                     MATKYAEGVLAVKYRVKDRNGQFSGGPMYYIEKGLGRRFKPLAMLFAFSGMLVALFGIG
                     TFPQVKAIVSSTENSFGVPPIVTALTIAVLTGLVTIGGLKSIAKVSTKVVPFKTGLYVL
                     ICIIVLIRFADQLPAAIALVLHSAFSTTSATGGFAGATIMLAMRSGVARGIFANEAGLG
                     SAPIAAAAAKTKWPAEQGLISMTGVFIDTMVICVMTGLTLLVSGVWSGPTDAGLMTQQA
                     FSSAFPLGAELLTIILIMFAFTTMLGWNYYGERCVEYLLGVKWIKPYRYLFIVLVGGGA
                     FIKLDAIWLLADIFNAMMAFPNLIALLGLSGIVVAETRTYMNSLYPNKNKGILAGANVG
                     AAIQVEEKGQTVNS"
     regulatory      complement(19631..19725)
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    19834..19852
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.42"
                     /tool="antismash"
     misc_feature    complement(19875..19890)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.74"
                     /tool="antismash"
     gene            complement(19990..21447)
                     /locus_tag="LJR53_RS19120"
     CDS             complement(19990..21447)
                     /EC_number="3.2.1.-"
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010348049.1"
                     /locus_tag="LJR53_RS19120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="WP_016818609.1"
                     /transl_table=11
                     /translation="MTKTLKGFPKNFLWGGATAANQLEGAFDVDGKGLSSADMIAYVPK
                     SERKNDHAIEISSERLEDILAGKVNARFPKREGVDFYHHYKEDIALFAEMGFKVFRMSI
                     HWSRIFPNGYDAEPNEAGLQFYDNVFDELRKYGIEPLVTLSHYETPLGLTQKYNGWLGR
                     EVVDHYVKYAETVFTRYKDKVKYWLTFNEINVMTMSPFTGGGVVIDRVENKQQAIYQAL
                     HHQFVASALATKRGHEIIPGAQIGCMLARIESYPHTCNPEDILKAQHENQMNLFFTDVH
                     ARGEYPNYMNRYFEENNIVIQTEPGDAEILKNNTVDFISFSYYMTLTVSAGPEGEKAAG
                     NLIGGVKNPYLQSSDWGWQIDPIGLRVTLNTFYDRYQKPLFIVENGLGAYDKVEEDGSV
                     HDTYRIDYLRQHIAQMKEAIADGVDLIGYTSWGPIDLVSMSTSEMSKRYGFIYVDLDDD
                     GNGTLQRSKKDSFNWYKNVIATNGEEL"
     gene            21659..22630
                     /locus_tag="LJR53_RS19125"
     CDS             21659..22630
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007431750.1"
                     /locus_tag="LJR53_RS19125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_123797566.1"
                     /transl_table=11
                     /translation="MSNLDQIAKLAGFSKATVSRVLNQSPHVSQETRAKILKIMQELDY
                     VPNRNAISLSKGQTLQIGIITSTINEIVLAFLDSFVEIAGQYEFQTIIYTSGEDKKKEL
                     QAFEDLKRKRVDALVIISCVNDTDFLSTYCKYGPIVAWQRMEHTDIRSVAMDQYEGYML
                     ALKHLIQKGYTRIANAFGRPSSINTHSRQRAYEQIMSEHNLPMLPHWNYSSIYNIRDGE
                     QVVRNLLQHREEFPEAILCANDYVAVGILCEARRQLLKVPEDLAIVGFDNTELAHTMGI
                     TTVQNPIMAQAQNAFFMLSPQLIGRQMELHSLEYSLIERTTT"
     gene            22864..23712
                     /gene="licT"
                     /locus_tag="LJR53_RS19130"
     CDS             22864..23712
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="licT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016818607.1"
                     /locus_tag="LJR53_RS19130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="WP_016818607.1"
                     /transl_table=11
                     /translation="MIIEKVLNNNVLLTKNDKGKEVIVMGRGISFKKVAGDQVDDHKID
                     KIFMLNENEFTARLTELLNDIPVSHLEVVNEIVTHAAEVLDTELSDNIYLTLTDHIHFA
                     IQREEKGLALKNAMLYEIKRFYKKEFAVGLDALQKIENTLGVKLGEDEAGFIALHMVNA
                     RIDGNEMKATLKMTEIVQHILNIITYHYGIVLDESSFSYSRFLTHLQYFAMRVIRKEVI
                     HSGEEFLYNQVKQTYTEAFACAQKINEYLEKTYDQYLSKDEYVYLTIHIHRVTERNNIS
                     G"
     misc_feature    complement(23750..23768)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.98"
                     /tool="antismash"
ORIGIN
        1 taggccatac atccttaccg ccgaaaccaa tcggttccac gccgttatcc ttgagcacct
       61 tcataacatt caccagttcg tcccatgtcg tgggcacagc aagattatat ttttcaaaaa
      121 tctctttgtt gtaaaacaga cctgtcagtg ctaccttacc catgtttaca ccgtatacct
      181 tgtcgttata ggtcatggca tttttgacat ctgtaggatt atagtttttg ataaaagctt
      241 gatctgacag atctgcaatg agtcctccct cgatccactg cttccacatc ggatcagcag
      301 ctcccttaga ccattcctgc ggtgcgccta cgaagctgaa tttcagagga ataatgtctg
      361 catcaccggt tgaacccgca ttcatacgcg tttgcatcag ttgatcataa gtggaatcag
      421 caggaaccgt cgtatactcc acctgaacat caggatactt ctcttcaaac tttttattaa
      481 attcctttat atagttatta atattctcct gctgccaatg aataattttt aacgtgacct
      541 ttttattccc gttctgccca gcttcgttac ctttaccgca agcggctaat accacgatta
      601 aagcggttac aacaagtaaa gaaaaacact tttttagcat tgcaaaattc cccctgtaat
      661 cttagaataa atgcactcac tcttacgaaa gcggtttagt taattacagc tactattatg
      721 tatcgaatag cctgtatttg taaatagcaa tttgtaaatt atcaaaaaat cattaactat
      781 cgttaaatcg aacttcatta tccataatat attaggattt atcctataat agcacggttg
      841 actctcttct atgaggtagc atagaatacg agtaatcatt aattttagaa tgcaaggtca
      901 aatgaactaa atcagtttag ttacggagga ttccatgaat ataaaaacaa tagctagcat
      961 ggcaggcgtt tcagtagcaa cggtttcgaa gatcataaac aattacacag atatcagtga
     1021 ggaaacccgg cagcgagtac tcaaaattat ggaggaaaca ggctatagac cttcctcctc
     1081 ggctaaaacg cttgctacca aaaaatctaa tctggtaggc gttatattcg ctggcaagct
     1141 gaatgtcgat tttagtcatc ctttttttgt agacatcatt aatgttttca aaaagcagat
     1201 tggcttgctc ggttacgacc tgctgttttt ttcaaatgag aaatttctgg ataatggaga
     1261 ggactatttg gctcgctcaa aatatttctc agtggacggg tgcattatta ttgccggaga
     1321 cgaagtggag aagagtgttt ttgatctcga tgccagccca atcccctgca tcggtgttga
     1381 tatcgaatta accggagcca gctcctgcta catcatgtcc gacaatcaga agatttcaat
     1441 gaaagttgtt gagcactttt acatgaatgg ataccgcgaa atgggtttta taggcataga
     1501 acgcccctcc ttggttatta aagagagaga agaagctttt atctcatcac taaagcggtt
     1561 tagccttgat gtcagaccgg aatggatcgt gtatggcaag gactatgcag cagaggatgg
     1621 ataccagatc gcaaaggcgt ggatacagca agaaaattta ccaagagcta tttttgcggc
     1681 taccgacctg cttgcctttg gtgccattcg tgctttcaag gagagcggct tgaaggtacc
     1741 cgaggatatt gccgtagtag gatgtgatga tattgaagcc tgtcgttata ctgatcctcc
     1801 actgacgact gtaaaacaag acaagcaaaa aataggtcgt ctggctgcta tggtgctgtt
     1861 tgacctgatg aataaacaaa tggatacgaa atgtattaaa gtggagcccg aactcgtcat
     1921 tcgcacctcc tgcggagccc ggcaacattg gaaccctaca agggttgagg gatagcacat
     1981 acctaaaaaa ggtgactcct gtcgaattca gaagtcacct ttttgcagtt atataacaag
     2041 agccctttcg tttaagccat tatttgtagg ccatcgtcgc attcacagcc tttttccagc
     2101 cttcatacag gctgtcacgt gttgcttcat ccatcgtagg ggtaaaagaa gtttccactc
     2161 tcactcgctt acgaagttca tctgtactct tccagtatcc tatcgccaat cctgccagac
     2221 atgcggcacc cagcgccgtt gtctcatgga taactggccg ttccaccgtc gcatccagaa
     2281 tatcgctctg gaattgcatc aggaaattgt tcaacacggc tcctccatcc actcgcaaca
     2341 tcttcaccgt aattcctgaa tcaatctcca tggctgtaag cacatccttg gtctgataag
     2401 cgagggactc caaggtggca cggataaaat gctccttcgt ggtcccacgt gtcagaccaa
     2461 acatcgctcc acgcacctcg ctatcccagt aggggctgcc cagcccgaca aaagcgggta
     2521 caagatatac tccttctgtg gaggaaacac gggccgcata aggctcactg tcctttgctt
     2581 cacggaacat gcgcagccca tctcgcagcc actggatcgc agagcccgca acaaacacac
     2641 tcccttcaag tgcgtattgc actttgcctt cctccagccc ccaagcgatg gtcgtgatca
     2701 gaccgtgctt ggattcaacc ggctgatctc ccgtattcat caacatgaag caacctgtac
     2761 cgtaagtgtt tttgatcatt cctttttcgt aacaagcctg accgaacaag gctgcctgct
     2821 ggtcacccgc tgcaccggcg atcggtacat tctgaccaaa aaaatgataa tccacggtgt
     2881 gcgcatatac ctcggaagaa ggccttacct caggcaacat gattttcgga actcccagaa
     2941 tatccagtag ctcttcatcc cactttagct cataaatatt gtacatcagc gttctggccg
     3001 cattggagta gtctgttaca tgggcctttc cgccggatag tttccagatt agccacgagt
     3061 caatcgtacc aaataataag tcacctcgtt ccgctttttc ccgcgctcct tctacatggt
     3121 ccagtatcca ctttacttta gtgcctgaaa aatacggatc gatcaatagc cctgttttgc
     3181 tgtgaaacaa ctcctcatgc ccttgccgct tcagttcttc gcaaatatcc gaggtttggc
     3241 gtgattgcca tacgagtacg ttatacacgg gtaatcctgt atttttgtcc cacacggcca
     3301 ccgattctcg ctgattggta atgccgatgg cagcaatttg ttttgctttt acaccggatt
     3361 cggaaagaca ggaggcaata acgcccagaa tagaactcca gatttcattc gcattctgct
     3421 ctacccagcc ggggtgagga aaatattgcg gaaattcccg ctgggccgag tacaccacat
     3481 ctccttcgct attgaacaaa atcgctcttg aacttgtcgt tccctggtct agtgacaaaa
     3541 tatattttcc catgttcatc tctccctgtg taaatccatc gtttttacgc tgtaagcttg
     3601 tgatccattt tatgattttt ataaatacga ctaatacgga aggtaatcaa gagtacaacc
     3661 acgataaccc ctaataaaat ccagaacgcc ggagtcatac tccccttaaa aacggcctga
     3721 taaaacggcc ctgcgaaaga tccccccaat agcggtccta caatgggcac ccatgcatat
     3781 ttccagttgg atgctccctt accgggtatc ggtagtaaat aatgcatcag acgcggccca
     3841 aaatccctcg ctggattgat ggcatagccc gttgtgcctc caagggataa accgatactg
     3901 acaaccaaaa aaccaacaat tagcggttta aggccgtctg taaacgaatt ggcaccaaac
     3961 gacagtaaag caagaacaaa gataaaagta cctatcattt cactaagcac gttaccaaac
     4021 ggatgatcaa tagctggtcc tgtcgcaaat acactgagtt tggctgctgt gtcctccgtc
     4081 tctttccagt ggggccaata atgcaaaatg acgatcactg cacccgccat ggctccgaga
     4141 acctgagcca caatataacc gggaacatcc tgccatggaa aactaccctg aaatgccaac
     4201 gcgagtgtaa ctgcgggatt caaatgcgct ccgctgattt ggcccaccgc atacacccca
     4261 atagctaccg cgagccccca ccccaatccg accacaatcc agccggaagc gtgggcaaaa
     4321 gactttttca gggacacccc tgcgcacact ccgccaccta gggcaataag aatcattgtc
     4381 cctatgaatt cggctgcgta tggcgacata caaccaacct cctcaataga tcatccgatt
     4441 ttgatcgttt tcatcgcgca aaaaaaagaa aagccatcac aaaccaaccc tgtgctgtaa
     4501 catgggatgt ctgcgtggct ctcttgtctc cgtcacgatt attaacttaa atttgatatt
     4561 atataagcat gtaagcgatg tcaactgcgg atttacgtct tctgatatcc taaaataatc
     4621 gttgaccatg ttagattgcc cgatttatga tgtaaaaaaa tggctgaatg aaaggatttc
     4681 aggatgaata cgacactccc aaacttgatg atgaagggaa gaatgttatg ctgaaatttc
     4741 tgcaaaaaat cggcaagtca ttaatgcttc cagtagctac attacccgcc gcagggattt
     4801 tgcaagggct ggctctcatt aattatgaga cggatattcc gcttggccct ggagttggtg
     4861 gatttctgaa tcattatgtc actccttttc tgaatgaagg ggcgggtgct atctttggca
     4921 atctggcgct cattttctcc atcggtgttg ctattggtct agcaggcgac gcggtagccg
     4981 cactttcggc agtcattgcc tatttggtgc tgacccgtat tttggcggcc gtaccgggta
     5041 tatttgcgta tattccagac gacgtcaagc tggacatggg cgtattgggc ggtattttta
     5101 tcggcggatg gtctgcttat ctgtttaaaa aatatcataa tattcaactt ccagattggc
     5161 tcggcttttt ttcgggcaaa cgttttgtcc ccatgattac agccttcacg accatgattt
     5221 tagccattct gctcggcatg atctggagtc cgatacaaga tggcattgca gccttcggca
     5281 actggattgt tggctttggt ggaatcgggt caatggtgtt catgattgcc aatcgactgc
     5341 tgatcccgct cgggctgcat catgtactga actcgatcgc atggtttcaa attggcaact
     5401 ataccaatgc tgcaggtgaa gttgttcatg gtgacctgac acgttttttc gcaggcgata
     5461 catcggcggg tatgttcatg tccggcttct tccccattat gatgttcgct ctgccagcgg
     5521 cggctctcgc attcatccat acggccaagc cggaaaaacg taaagctgtc gcttccatct
     5581 ttatcggttc tgcgctggcg tcgttcctga ccggtattac tgagcccctc gaattttctt
     5641 ttatgttcat tgcacctctg ctttacggca ttcatgctct gctaacaggt ctgagcggcc
     5701 tagtcgtata cctactggat gtcaaactcg gcttttcctt ttcagcagga ctcattgact
     5761 atctggtcaa tatgaagctc tccacccatc cattgcgaat gatcccgatt gggcttgtct
     5821 tcgccctcat ctattatttt ctgttccgct tcatcatcct caaattcaac ctaaagactc
     5881 ccgggcgcga agacgatgta gatgacaccc ttctatttga ggctaacaaa tccatacccg
     5941 ttggaaaagc aagcgcctca tccggcaccc agtccagtca ggcaggccag gtcctaacct
     6001 atctcggcgg ttcagacaat atccaaagca ttgatgcctg catcacgcgg ctgcgtcttg
     6061 tcgtcaagga cgacaaagcg gttaacgatc aagctcttaa gcagctcgga gcgtcaggaa
     6121 ttatcaggct tgggaacggt accctacagg ttattttcgg tactcgatcc gaagctctga
     6181 aagatgagat acaacgattg atgtcatgaa gctaatcccc tgccttaagc acgtgcgatc
     6241 ttcctataac agacgcacgt gctttttttt atggataaac gtttcaaatt ttttgttttt
     6301 ggttaaggca atgcacataa atgggtaaca gcttcatatg atggagctaa accatttaca
     6361 acttgttcag caggcagatt attcagacag caaggaggga aatgatgtga agacagtaca
     6421 atggcaatgg ctggtattat gtcttgcttt tctcactatg attagtggtt gtagtgggtc
     6481 cctatcctct aaaggtcaat catctgaagc taatttgtca aacagtaaaa agataacgct
     6541 tacattgtgg tactggaatc gttctattga cgatgaattg ctcgtccagg ccgaaaaaca
     6601 gtttcccaac attgaattaa aaactcaaaa aataggcggt gactttaaag ccaagctgaa
     6661 gacaacgctc gcagctcgtt ccggtgaacc agacatcgta gctctgaacg actggatggt
     6721 ggagctattc ccgagtgcgg atcgttttta tgatctaaag gaactcggag cagaccgact
     6781 gaaggatcaa tatttggaat ggaaatggaa tcagggcatc actcctgatg gtaaaatgat
     6841 tgcatttccc atggatactg ggcctaccgc cctcttctat cgaagcgacc tgtttgaaca
     6901 ggcaggcttg ccaagtgatc ctgaacaggt cagcgcctcg atccgcacat gggatgatta
     6961 tatggcagcc ggagaacaac ttcggcagaa attcggaagc cattcatttt tggccgataa
     7021 tattgtaaac gtttacaatc aggtactcgc tcaacatacg aacctgtact tcaagccgga
     7081 cggaagttat atcggcaatc aatctcctga catccgcctg ggctggaaaa ccgctgtgaa
     7141 tttccacagg aagcatctgc tcgccaatgc agatggctgg actcctgaat ggaatgcttc
     7201 ggtcaataac ggcaaaatcg cctcgttcgt aggggcaatc tggatgaagc aagttctcac
     7261 agaagccgca ccggatacag cgggcaaatg gagagtcgcc cgtgctcctg gaggagacgg
     7321 aaatctggga gggtctttca tctctatcct caaatctagc caacacccca aagaagcctt
     7381 tgaagttctg acctggctgc aaagcccgga acaccaactg gaagcctacc ataaaatcgg
     7441 cctgttccca tccactcccg gcgtctatga cgatccagtc atggagacac ccgagccttt
     7501 ctttggtggt caggccactg gcctcatttt tgccgcctcc gcacgtcagg tgaaaaatag
     7561 ctatttcggc gagcgctatc ctgtcatcca cggcattgta acccgtcgtc ttgccaatgt
     7621 ggccaaacaa aatgccgatc ccgaagcatt atggacggaa acaatgcaac gaattgaacg
     7681 ggaattacag cgttaaaaaa caaaacttca aaaaaggcgt gtggacaata tgctgagaga
     7741 aatctggaag caccgggccg tttatgctgc gatctcgcca ttttatttgc tgtttggcat
     7801 ctttggcttg tttccgattg gcttttcatt gtacctggcg tttcacaaat gggacgggat
     7861 cggagacatg acctacaacg gctggggcaa ctttcgttac cttgtgacag acaacgaatt
     7921 ttggcaggct gtaggtaata cgtttgtgat ctgggtgtac gccacgattc caatgctatt
     7981 tctagcactc attgttgcct ttctgcttta tgcccctttt gtgaaaatgc gcaccttatg
     8041 gcgagttgga ttcttcctgc ccaatgtgac atctattgtt gctgttgcca tcatctttgg
     8101 cgccttattt gccaacaatt ttggatttct caactacctt ttgcagctct tggggctacc
     8161 tatgatccaa tggctgaatg tgccatgggg tatccaaatc gccatttctt ccatggtcgt
     8221 ctggagatgg atgggttaca acgccattat ctatctggct gggctccaga gtatcccaca
     8281 tgtgctgtat gaggccgcca aaatagacgg ggcaaccgga gcgcaagctt ttttccgcat
     8341 caccattccg atgctgcgcc cagtcattct gtttacagtc attacgtcca ccatcggtgg
     8401 gatgcagctg ttcaccgagc cacaggtcct ggtcggtaat gacggcggtg ccggggcaag
     8461 tggcatgacc atcgttttat acctgtaccg cgagtcgttc attaacaact attttggata
     8521 tggcgctgct gtcggatggg gcatgtttct catcattgct ctattctcca tcatcaattg
     8581 gaaactcgtt caaggtaaaa aataacgatg gaaggagctt taccacatga tgcagacacg
     8641 tgcaaaatcc attgttttat atgctgggct gttggtaggt atcatcctgt cgatgtttcc
     8701 attttactgg ctaatcgtca tggcaacccg tacaacctca gacatctatc gttttccgcc
     8761 acaattgtgg ttcggcagcc acttcctgga taacatcacg agagtattgc agcagattga
     8821 ttttgccggc gcctttttga atacgctttt tgtagccagt tcgattaccc tattggtgct
     8881 gttttttgat tcactggccg gttttgcatt cgcaaagttt gattttccgg gcaaaaaggc
     8941 gctattcgtc attctgctag ctacaatgat ggtcccttca caactttcgc tcgttccctc
     9001 ctttgtcatg atggcttcct ttggatgggt aggtacgttc aaagcgctca tcatcccggg
     9061 tatggtaaat gccttcggga ttttctggat tcgtcagtat gcagaagaat ctattcccaa
     9121 ggagctcctg gattcggggc gtatggacgg gtgcagcttt tttcgactgt actggaatgt
     9181 agcactgccg attttacgcc ctgcgttcgc ttttctcggc gcatttacct ttataggagc
     9241 ttggaatgat tacttatggc cattaatcgt tttaacggat gagcgcaaat tcaccctcca
     9301 gattgcattg tcgcagttga acgggattta caatacggat tatgcgatgg tcattgctgg
     9361 caccctgctg gctgtacttc ctcttattat tttgtttctt ttcatcagcc gccaatttat
     9421 ttccgatctt gccgctggag cgatcaaaga ttagccttca cttgaatccc cttttacttg
     9481 ctctaaagcg tcatcgaaac tggacttaag ctctggagag gaattgcaca actatgagct
     9541 ccgtgcgatt ttattaattg gaacgattgc tctaaacgga acacaaaata ggctacttcc
     9601 gaggctgagt ttacacacga ttgaacatgt actgtctacc tgttatccat atttccttgt
     9661 aaattagcct ccatagttat ctaacgatta ataaaaatcg cttccactca tttaacagag
     9721 tagaagcgat ttttcaaaaa ttatataagc gtttctctga taggtcaact taaagccata
     9781 tcatagtttg cactactatt catttgccta tcagagcgac atttacatgc gcaattcgag
     9841 ccatgtccga agtcatgaag tatattatta gcaccggaag aacaaataca agataaagga
     9901 acaattccaa gggtatttgc cattaaaggc ttccttccaa atggatttac aattctcaat
     9961 ttataatcct ccttcgactc attttgatta tagattggaa ttacaccaat gtaatatggt
    10021 ttaattcctc taataaatgt ggtttgtgtt ccaagatagt atgatagctt atcaatgcat
    10081 gttccagcat atctaaagaa cgcctacaag ctattctctt tttttcgata ttaaacttat
    10141 cactatcgta acattcgacg taacaaaccg aacaaaggcg tatagcccaa catttggaac
    10201 actgggacaa actctcctta ccatagtcgt ctatataacg atcgattaat acagattcgt
    10261 ctataccact ataaacgttt ccaactgaag gtgattttcc aatgcgctcg cataaatgaa
    10321 agtctccatt taccgttaca taaattcttc ttgaggcagg tgaacagcag ccgtttaagc
    10381 aatagtccgg gtaaggagtt tcagttaaaa tcctatcatg tattattgag aattgtttgt
    10441 gtaaaaaatc gattgtaaag ggagtatttt ttgatataga agtattattt aacattagat
    10501 caattgtcca gttccctaca gggttatcat aacaatgcat agagcttttt tcagtaatcg
    10561 ttttttctat gtcagacgag tgtctcacat aagaaatatt tttagtaata tccttaggta
    10621 cccacgaaag agaattgaag aaattttgaa tttttttcat aactacatca ttagctggtc
    10681 taggtgttac catgcttagc gatataagag aattactctt ttctccataa gcattaatta
    10741 gatgtttaag accattaatt gccttgacat acgtgccctc accattttta aataccctcc
    10801 tacaatcatg tatttccttt ggaccgtcaa tactacaaac tactccaaag ttaggaactg
    10861 tagatagata ttctgcgatt tcagcagtca ttaaggttaa gtttgttgtc attgaaaatg
    10921 ttaaatcttt atcagcacca ttttttaaag tatagtctac acaatgcttt aataatttaa
    10981 attctattaa tggctccccg ccataaaaag ttaccgccac ttttttacct gagtttttca
    11041 gagtataatc gattgctaac tctgctactt gccaggacat gtgcctgcgt ccaaattccc
    11101 tgaagtctat gttccctgaa tgatatatac aatagtggca tgccatatta cattgttcgg
    11161 tcaactccag agtaacctgt tctagatgac ttcttgcatt ttctaaaacc tcatcttttg
    11221 atagtgcaaa ggataaaaga ggaggtgctt ggaataaatg ctgttcctgc gcaacatgta
    11281 ttaagtcaat tagaatagtc aatgtatcat cattaacttt ggtaggtttt attacctctt
    11341 cgatatctcc gtacacttgt aagttattta gaaatacata ctctatttca gtgcattcca
    11401 taactttgcc tgtgcccaca tcatacaaat aggatttatt ctttgtctga aacaacttaa
    11461 acaatcgtga gtaattccca tactgttttt tgatgtttct aaagaactcc ataactgtgg
    11521 aatccaatat catcacgttc ctcttgggtt tcaatattca aaatatggtc acatgctgct
    11581 aatagtctct ggtcatgtga tactacaatt gttatccttc ttgacttttg cttggtcaat
    11641 atttctataa gtccacttac actctttgaa tctaaggctg atgtgggctc atcaagaatc
    11701 gttaagaaag aatctttact taatgcacga atcaaagcta atttttgctt ttcaccacca
    11761 gaaaagttgc ttccattttc gtttattagt atattttcaa ggttagcttt tgttattatc
    11821 tcttcaagcc caaaagctgt tataagctca tcttgattac tggcaatctc tttagaaaaa
    11881 gtaattccaa atttcaaata ttcctttatt ggtagattta aaaactccgg attctgttct
    11941 acataagaaa ttctataacg cctcatatca agcatatcta tatctttgat ggagcaatta
    12001 ttaaaagcta tttctcctgt gtaaagatca ctataaagac ctatcagagt attaagtaat
    12061 gttgttttgc ctgaaccatt gtgaccacaa atcccgtaaa ttcccccctt aaaaaaatca
    12121 taagaaaagt ctctaaatac gctttcctcg gaatatttaa cacctaattg tttaatactt
    12181 attttctcta aatcttcaag tgttgtacta ccataaatat cattttcaga gttcataacg
    12241 tcatttaacc gttctatcga tactttcgtc tcttggtatg aacttgctaa gcttaataaa
    12301 tatgaagttg acgagatgat cattgaaagg tacgtgttaa ttatggtgaa ctgccctata
    12361 ctcatttggc caattacaac tttatgacct ccaattccga ttacaaatat atagcagatg
    12421 atcaatataa attgatttag attggagaaa atataattag tttttacttg tgaagtcgca
    12481 actctaaata atgaattaaa tgctttattt agccgctcat tcatttcatt aaagagtaca
    12541 ttcttcttta taaaaaccaa tttgttaatt tgttcgactt ttttagagta gtattcattt
    12601 gcttcttttt tgtatttcag atttgcttta tacaattttt ttctaaaaac cacatatgta
    12661 aatatataaa aaggaataag cgagaaaatt ataacgcata gtagtacatc agcttttaaa
    12721 acaataatac cactgataat tattgtgatt acttgcaata ctaagttgga aatattattt
    12781 gaaaaaaagt caactactgt ggatgaatca ttattaattt ggtcaactaa gtatgcatta
    12841 tccttatctt tgaagaccga cagtttagtt ttgaatatct tttgatagat atcattgcag
    12901 atttcgtata ataataaatt attcaatttc gtagagaaaa gggcagttaa atattgtatg
    12961 agaatgttta ctatatttat aatccccagt aacagtacaa aatataaaat gatacttata
    13021 ttactttttg atactaaata atcaatatat atgcctgtga tgtaaggaac aataattcct
    13081 ataatccaca atactgaagt aacaacaatg taaaaaaata catacttgcg cgtttttgaa
    13141 aggtattttt tcaagtattc taggactatc atattcatca cctatgtttc atattaggta
    13201 aatcttagcg agatgctaaa aacagcatct cgctaagtaa tgttacttct cttaagctac
    13261 atcttgtagg aacaagaaag agtgcagcca cttgaaccgt ggaaaggaca atgtgcactt
    13321 acttgtacag cactttttac caatacgtcc atagtttttc cctccttaaa atttaattta
    13381 tataaataac atacagttta aaaactatat gctacttatc acttttgagc tgcaatagaa
    13441 aatgcactgt tttcaagcgt gatatttatc tttgctttac ctgcaccatt tatatagtta
    13501 tatgttaagt ttggtctaaa caatggccat cccgcaggaa cacttaatgc acttgcagtc
    13561 gtcttaactg taactgtgta atccgaagct cctttactaa aagttaagga acctgaacct
    13621 tttgtattgt cataactaat ggcttttgag tatcctacag gcacccgaac tgacattgag
    13681 gaaccatcta cacctgtgat atcaagatta gtatttagct ctggaagtga aactccagac
    13741 tttgtacttt ctaccgttat tttttcataa cttttatcag gaattaaaat attaactctg
    13801 tcggaaatgc cgttagctga gcctttcccc tttactgtga tgtaaattgt agatccactt
    13861 aatgtagaag tgacagtata caaggatttg ttatactcat aactaaaatc acttgctgaa
    13921 gtttttgtaa cggtgacatt acaatttata gccgttagat tgatattctt aacatcattt
    13981 gaagctgcat tacttgaagc acctaatggc atccccataa gtaagaaacc acataaaaca
    14041 atacacattt tttttagcat taacatgatt cagaaacctc cttcttattt cccgttaatt
    14101 gtccagccag taatactttc gtgcactcgg taatatactc ctgcaaatta taacgatatt
    14161 gctcgcatat gttaaagtct gccattctat tgtgaggaca tcctcctaaa cacacaggta
    14221 agtacttaca gtctgaacat ttttcatctt cagtaggatc atataataaa taacaaccaa
    14281 gaagctcagt attccatttc actgatgtat cttcatttat atttccaaca cactgctcaa
    14341 taattccaat atcgctccaa catttatata aatgaccaag aggatcaata acgaaactat
    14401 tatatttgtc cgcagaacaa taattacctt taggtgcagg ataaatataa ctaattggga
    14461 tatcattttc cgacataaat tttaaattaa attttgaata catctcgtct gtcaagcact
    14521 tagttccctc atactttcca ttcgtcggcg taactaatcc tagataaggt attacatttt
    14581 ccaataaaga attttccttt aagaatccta cgatttcatg taacttcaac cagttgtctt
    14641 ggtcagtatt tattctcata aatatcttaa tcatcccttt aatttgcttg aggttattca
    14701 ttatgacatc aaatgtccct cttccactta ctaaagggcg tctaagatca tgtacttctt
    14761 taggaccgtc aacagtgact tgaatatcat ttactccaca tgatattaac gtttgaactt
    14821 tttctttatt taaaagatag ccgtttgtaa tgacactggc cgtatattgt atattgtttt
    14881 ctttacatat ttccaaaaaa tcttccgata tcctaactat ctgcttcatt gcaatcaagg
    14941 gttcaccgcc ataccatgta acattaagag tgtcaagttt actagcattt gttttaacaa
    15001 aattgactat actttgagct gtttcttgac tcatagtttt gttatgatat tggtctttct
    15061 caaaacagta tacacatcta aaattgcagg ccattgtagg ggcaattgtt agcattaaat
    15121 tagaagattc aaaccgattt tttaagaggt ttacctttac atatgctttt tcattcatat
    15181 tatcttctac gatatagcca cattcgataa gatttttaag ataagtatca ttatttattg
    15241 ccaattcatt gtttgtaagt tcacaaaact gtttatagta ctccggttca agaactgcca
    15301 atgcacctgt tcgagaatta taaagtaccg ttttatcggt attttcaata atgtcattaa
    15361 aaataaagtt atattgcgaa gctttcattt tagccctcct tagaatggat gcggtcccta
    15421 tgtaattatg aatcgattaa ctagtgacaa aattcacata agttttaaaa ataaaatgta
    15481 cgctcattct gagttgtaat tgcattctcg cagtgcacac tagccaccaa gaatagatgt
    15541 ccatcatccg aaaccggact gaatttaaaa gccatcctac accttcatag tttattcata
    15601 tactttattc tctctggaca atatctatac tagatagctt ttccttctcg gcttttaatg
    15661 tagcataagg caaaaagaaa aaataagctt gtatcctgaa atgcaaaaaa gtccatctca
    15721 acaaccaaat atgtcagctt catgtgagat taatattttt gttacctata tttctttaat
    15781 ggcaaagtac gttacttgtt aattctttgt ttatatgtcc aaagaaagta aaggattaga
    15841 ctgcttgaga cagcaacaaa gattaaaagt actaggagcg tgcaactgct tgttcctgcc
    15901 gttatcgtga cgcgaactga accagtagag ccttaactga atacttttat aaaggctgaa
    15961 aataaggttt ctaagcaata aagaagaacg tatccattcc tcgcctgggc tacgtcctct
    16021 ccacagtata agtatgcatt tgaactttta ctaacaaaaa ttccataacc tgatggtaat
    16081 ttttttcata tgtaaaacat cacttcgaat agactttttt tacaatatac tggatttata
    16141 taacatattt gaggtggtct atttgtttca agttgctgtt tgtgacgatg atcccgcaat
    16201 gcataaaatt ttacaacact ttttcatgtg tatgtcagta agtgaatcct tagattttaa
    16261 tctacaattc tttttatctg gggaagatct aatcaaatct tacagttcac aagagcgata
    16321 cccctttcat attatcttgt tagatattga aatgagggaa ttatcgggaa ttgaaactgc
    16381 aaaacttatt cgcctttttc ctgaccgaga agttcaaatc atatttctaa ctaactatcc
    16441 agaatacatg ctagaaagtt ttgaagtaca agcatttcaa tatttactta aaccccttac
    16501 ttataaactc tttgtagaaa aaataaataa actatgtcat tatatgcgtt cttcagtatc
    16561 ccactttctg tctgtgaaaa ataaaactga gcatcttgta ttgagacact ctgagatcat
    16621 agtcatctca aaaggtgaaa acaattacat ccataatgaa ctttgtattg caacggattc
    16681 acacaactat tttatttccg gaacgttgaa agcggtttat gaacaattaa aatatccgtt
    16741 tgtgtttata cataggtcaa taattgtgaa tttagttcat atacgtaagt tttcagctac
    16801 ttctgttatt atgtcaaacg aacaagaatt ccctgtaggt cgttctcacg ctaaatcact
    16861 tcgtgaggcg tatgctcgtt ttataatttc tcgttttcag gaagggtgag ttttttgaat
    16921 cattgcgttt acattaatgt cacctcgttt tctaattact ctttattttt atttagcaca
    16981 acaaagcaaa gtcatttttc caatccaata gttaaccttt ttttactttt cgcctcttta
    17041 cacttcatac ttattacagt actagtagtt cattatttta aaaaaggaag gaaatacaag
    17101 atagggattg tgtattattt tgtaatatta ataggaacat cgtttaactt gctcatacat
    17161 tacggtttat tttcttttat gaaacataat ttattcttta taatgtcaat catcagtatt
    17221 cttggaatga acgtgattat tgtctttcta acggacaagt tgatagaaaa gtcaaacctc
    17281 tcatgctttt ttcaaaagca aatgctgatg caagaaaaac gttataaaga aacaactcga
    17341 tctcttagtg atatcaaacg aagtattcat gatttcaaaa aacagttaat ttttgtccgt
    17401 gcttgtttac aagaacagag gacggaagag ggtgttaatc acatcaacca aactctaaaa
    17461 aatatagact caccaaaact tcatataaca acaggacatc tcgttattga tgctttagta
    17521 aatcatactt tcagcatcgc taataaaagt gggatagctt tcttccatca aatccatatt
    17581 aacccggcaa atattagtat tggaagtcat gatctatgta ttgtcttagg taatgttttc
    17641 gataatgcta ttgaagctgt aatgcagctt cctagaaaga aagagcattc aattcatttg
    17701 gaaattttca ccgataatat tgccctatgg atttatgttc gcaattcaaa aagtaattat
    17761 ctcaatacag cattctcaac caaaacatac aatccccctt taaaaaaaca tgggtatgga
    17821 ttacttaaca tccagcaagt gataaagaaa tatggtggtt atttaaatac aactattacg
    17881 gattcgcatt ttcaaattac gattatgctc ccatgtaata actcttaggt ttgtaaacgt
    17941 tatggattaa gagatattca gaataaataa aatgtcggta atcaccagtc ttataaccta
    18001 aaaaaaggag taccctcaag cctgtgatgg ctgagaatac tcccttttag tatttatgaa
    18061 tttaccgttt gtcccttttc ttctacttgg atagccgccc ctacattggc accagcaaga
    18121 atacccttgt tcttattagg atacaaagaa ttcatataag tccgggtttc tgcaacaaca
    18181 attcccgaca agccgagcag tgcaatcagg ttcggaaaag ccatcatggc gttaaaaata
    18241 tctgccagca gccaaatcgc atccagttta atgaacgcgc ccccgccaac cagtacaatg
    18301 aacaaataac gataaggctt gatccactta accccaagca agtattcaac acagcgttcc
    18361 ccgtaatagt tccagccgag catggtggtg aatgcgaaca taatcaggat gatggtgagc
    18421 agctctgctc ccagcggaaa tgcactggaa aatgcttgct gagtcatcaa gcctgcatcg
    18481 gtaggcccgc tccacacccc gctcaccagt aacgtcaacc cggtcatcac acaaataacc
    18541 atcgtatcaa taaacacacc cgtcatggaa atcagccctt gttccgcagg ccatttggtt
    18601 ttggcagctg cggctgcaat cggtgcgctc cccaatccag cttcgttggc aaaaatacct
    18661 ctggctaccc cactgcgcat ggccagcata atcgtagctc ctgcaaatcc gccggttgcc
    18721 gatgtagttg aaaatgccga atgaagcaca agcgcaattg cggcaggaag ttggtcagca
    18781 aatcgaatca gtacaatgat acaaatcaat acatacaggc ctgttttaaa aggaacgacc
    18841 ttcgtcgata ccttggcaat gcttttgagt cctccaatgg tcacaagacc tgtaaggaca
    18901 gcaattgtca gcgccgttac aatcggcgga acgccaaaac tgttttcagt cgaagataca
    18961 atcgccttga cctgagggaa tgttccaatt ccgaacaacg ctaccagcat ccctgaaaaa
    19021 gcaaacagca tcgccaacgg tttaaaacgg cgtcccaggc ctttttcaat ataatacatc
    19081 gggccgccgg aaaattgtcc attccgatcc ttcacccggt attttaccgc aagtacacct
    19141 tccgcatatt tcgtcgccat cccaaagaag gctgcaacga ccatccagaa caaggcaccc
    19201 ggcccgccca gcttaatggc tgtcgctaca ccgacaatac ttcctgtacc gacggtagcc
    19261 gccaatgccg tactcaaagc cgcaaaacta cttacatccc cgctaccttc attcggggcc
    19321 ttaccgatga gcttgatcgc caggggcagg cggaatacct gcaacatttt tagacgtatg
    19381 gtcagccata accccgttcc cataacaagg atgatgagag gcgcccccca tatccaactg
    19441 ctaatcgttt ctaacacatg taccaaattc atttcaaccc gctcctccag catagtagaa
    19501 aacaaaaaag agtcaaatct gttgattcga ctcctggaga ggttaaaggc acgaaaaaat
    19561 acaaccatct tgtgcaggat ttcacctcta aaagcttata aaaagcctag ggctatccct
    19621 gtcacaggtt attcgcgtct ctgtcctttt gcctgagagt ttaagcagat gtgatctgcg
    19681 gtgcaccttc ggcgcccaat taagggtctc tccagagttc tgtccgttta cggtccctgc
    19741 tcgttgctgt aaatcagcct aagcacctga gagttttgcc ccttcggttg gaactttcat
    19801 tccatctccc gcaaacatca accagacata tgaaattttt attcattata cagaaaaatt
    19861 tcagcttatt acaagtgaaa aatttgtgaa gccctctgaa agaaccaata gagtgtctat
    19921 acaaaaagcg ggtacagcag attgcatcct gaggattttc tctgctgtac ccgccaaaac
    19981 gatatggaat tacaattctt caccgttggt tgctatcaca tttttatacc agttaaatga
    20041 gtcctttttg gagcgttgaa gcgttccgtt accgtcatca tccagatcaa cgtaaataaa
    20101 tccgtagcgc ttggacattt cggacgtaga catgctcaca aggtcgatag gtccccagct
    20161 ggtgtaacca atcagatcaa caccgtcagc aatcgcttcc ttcatttggg caatatgctg
    20221 acgcaagtaa tcaatgcgat atgtgtcatg cacagagccg tcttcttcta ccttatcata
    20281 cgcacccagg ccattttcca cgatgaacag tggcttttga tagcgatcat aaaacgtatt
    20341 cagtgtaaca cgcaggccga tcggatcgat ctgccatccc cagtcggaag actgcagata
    20401 cggatttttc acaccgccta tcaggttccc tgctgccttt tcgccttctg gccctgccga
    20461 tacggtcaag gtcatatagt aactaaatga gataaaatcg accgtgttat ttttcaaaat
    20521 ttcggcatcg ccgggttctg tctggatcac aatattattt tcttcaaaat agcggttcat
    20581 atagttggga tattccccac gagcatgcac atccgtaaag aacaggttca tttgattttc
    20641 atgctgtgct ttcaggatat cttctgggtt acacgtatgt gggtagcttt caatgcgggc
    20701 cagcatacag ccgatctgag cgcccggaat gatctcatgt ccccgtttgg tcgccaatgc
    20761 acttgctaca aattgatggt gcaatgcttg atatatcgct tgttgcttgt tttctacacg
    20821 gtcaataacc acaccgccgc ctgtaaacgg gctcatagtc atgacattaa tttcgttaaa
    20881 ggtcagccag tattttactt tatccttata gcgtgtaaat accgtttcgg catattttac
    20941 gtaatgatcc acgacttcgc gtcccaacca gccattatat ttctgtgtca aacctagcgg
    21001 tgtttcataa tgcgataatg ttaccaaagg ctcaatacca tacttgcgca gctcatcgaa
    21061 tacattgtcg tagaattgca atcctgcttc attcggctcg gcatcatatc cattcgggaa
    21121 aatccgcgac cagtggatgg acatccggaa tactttaaag cccatttctg caaacaaggc
    21181 aatatcttct ttgtagtggt gataaaagtc cacaccttca cgctttggaa aacgggcgtt
    21241 taccttccct gccaagatgt cctccagtcg ttcggacgaa atttctatag catgatcgtt
    21301 cttacgttct gatttaggta cataggctat catgtctgcg ctggacagac cttttccatc
    21361 tacgtcaaaa gcaccttcca attggttggc tgcagttgcc ccgccccaga ggaagttttt
    21421 cgggaatcct tttagcgtct tcgtcatggt atgaaaacct ctttccttaa tttaatgttt
    21481 tcactttagt cagtaacccg tcaggtgctg caatgcgaat ccataactaa cggtaaccgt
    21541 tctcctttga aatgcatcga cagatgcttt aaaatagacg taatgccctc ataaagcatc
    21601 ctaattgttg taacgcgttt catgtcaagt atttttttct caggtgagga gaagcatcat
    21661 gtcgaatctt gatcaaattg caaaactggc gggcttttcc aaagctacgg tatccagagt
    21721 gttaaatcag tccccccatg taagccaaga aaccagagct aaaattttaa aaatcatgca
    21781 ggaattggat tatgttccta atcggaatgc gatctctcta tccaagggtc agacgcttca
    21841 gattggtatc atcacttcaa ctatcaatga aattgtgctg gcatttctgg acagctttgt
    21901 ggaaatcgca ggccaatatg aattccaaac cattatttat acttcgggag aagacaaaaa
    21961 gaaagagctt caagctttcg aggatttaaa aagaaaaaga gtcgatgcgc tggtcatcat
    22021 ttcctgcgtg aatgacactg attttttgag tacctattgc aaatatggac cgatcgtggc
    22081 atggcaacgt atggagcata ccgatattcg ctccgtcgct atggatcaat atgaaggata
    22141 catgttagca ttaaaacatt tgatacaaaa aggctataca cgtatagcca atgcttttgg
    22201 tcgtccgagc agcatcaata ctcacagcag acaacgagcc tatgagcaga tcatgagtga
    22261 acacaatctg ccgatgctgc cacactggaa ctattcttct atttataaca ttcgtgatgg
    22321 cgaacaggtc gtgcgcaatt tgttacagca tcgtgaggaa tttccggagg ctatcttgtg
    22381 tgctaacgat tatgtagcag tgggcattct ctgcgaagcg cgcagacaat tgctgaaggt
    22441 accggaagat ctggcgattg ttgggtttga taacacggag ctggcgcaca ccatggggat
    22501 tacaacggtt caaaatccca ttatggctca ggcacaaaat gcttttttca tgctttcccc
    22561 tcagctgatt ggacgccaaa tggagcttca ttcgctagaa tacagcctca tagagcgtac
    22621 gactacttaa gggcacaatt gacttgcaaa ttaggcaaat gggccttgat atgaaatatt
    22681 ttttgtcgaa agagaataaa atatgttgaa atcgcttttt tttgtgctac aatagcacta
    22741 tatcgaagga ttgtgaccgg tgatgcgggc aatgcctgag ttcaattgag tgctattgct
    22801 aacaatagtg ttgaattgtg cttgggcatt ttttattggt aaaggatggg agggggaact
    22861 tcaatgatta ttgagaaggt gctcaataac aacgtcctgt tgactaaaaa cgataaaggc
    22921 aaagaggtca tcgtcatggg aagaggtatt tccttcaaaa aggtggctgg cgaccaagtc
    22981 gatgatcata aaatagataa gattttcatg ttaaatgaaa acgagttcac ggccagacta
    23041 actgagctgc taaacgatat tcctgtgtct catctggagg tcgtgaatga aatcgtgacc
    23101 catgcagccg aagtgctgga tacggagtta agtgataaca tttatttaac attgaccgac
    23161 catattcatt ttgccataca gcgggaagaa aaaggattgg cactcaaaaa cgcgatgctg
    23221 tatgaaatta aacgctttta caaaaaagaa tttgcagttg ggctggatgc tctacaaaaa
    23281 attgaaaata cgctcggtgt aaaattgggc gaagacgaag cgggatttat cgcattgcat
    23341 atggtgaatg cgcggatcga cggtaacgaa atgaaggcta cactaaaaat gactgagatt
    23401 gtccaacaca tattgaatat tattacgtat cattacggga ttgtgctgga tgagtcttct
    23461 tttagctatt cgagattttt gacccatttg caatattttg caatgcgagt gattcgcaaa
    23521 gaggttattc acagtggtga agaatttttg tacaaccagg taaagcaaac atataccgag
    23581 gcttttgctt gtgcccaaaa aattaatgag tatctggaaa aaacatatga tcaatattta
    23641 agcaaagatg agtatgtata tctaacgatt cacattcatc gggtaactga gcgtaataac
    23701 atatcaggct aaaaacttta tatcctcatc gttcatggat tgtgactggt aaggcaggca
    23761 aaacctaaac tgatggtgaa atcgacgttc ccttatagga ggagtgcgca gttttcacca
    23821 cgagtttagg tttttcttgt ttacaaggtt aaaaaagatg cacgccggcg catctcagca
    23881 acaaatgtaa acggtaaatc ctatcagtag caagaataac acttaaggag ttctgaacat
    23941 gagtgataaa gagctatcca aaaaaatagt gactctcgtt ggcggcgaag agaatgtcaa
    24001 ttcggtattc cattgcgcta cacgcttgag atttaaatta aaagatcgca caaaagcgga
    24061 caaagctgca ctggaagcaa cacctggtgt cattacagtg gtggaaagca gcggccagtt
    24121 ccaagtggtc atcggtaaca atgtaggtca ggtctttgag catatgatga cagaaacaaa
    24181 tctgcaggat gcagataacc caaatgtgaa aaaagaagaa tcttccgaaa aaacgaattt
    24241 tcttggcaaa gcggtcgata tcatttccag cattttctca cctctcttgg gtgctcttgc
    24301 cggagctggt ttgctcaaag ggattatggc cttaattgcg tcgctccatt ggattgatac
    24361 tgcaagcggt acgtatctca ttctgaacgc cgcttcggac agcgtgtttt atttcttgcc
    24421 tatattccta gctattacat cgtcccgtaa atttaagacg aatgcctttg tatcggtcgc
    24481 agttgctgga gccctcgtct acccggatgt tattgctgcg gtggaccatc cggcaaaact
    24541 ggcttttctc ggaattccaa tcattctgat taaatatagt tctagcgtaa tcccaattat
    24601 tctcgcggta tgggtacagt cctatgtgga acgttggttt aattcctttg ttcatcaatc
    24661 ggttaaaaac attatcgtcc ctatgctatc actgctagtt gttgttccgt tgacgttttt
    24721 ggcctttggt ccagtcggta acctgatcag ccaaggcttg gcgaacggtt ttacatgggt
    24781 gtacaattta agcccattga ttgccggagc tgttgctggg gcattctggc aagtatttgt
    24841 tattttcggc gtacactggg gcttcgttcc tattatgctg tccaatattc aaacattggg
    24901 ttatgacacg atgcttccaa tgcttacagc agccgtactt tctcaagcgg gtgcaacact
    24961 gggggtattc ctgaaatcac gaaatactca aatgaaagct ttggctggtt cttctacact
    25021 ggcagctgta ttcgggatta ctgaacctac gatttatggt gtaactttga aattgaaaaa
    25081 gcctttcatc tatgcttgta tttctggtgg tattgggggc gcgattatcg cttccggcgg
    25141 agcaactgca aaatccttct ccctgcctag tttactggcg ttgccaactt attttggagc
    25201 tgggttcttg tgggttgtta tcggcttact cgttgccttt ttacttgcag ttgtattggt
    25261 tatgattttg ggctttgatg atccaaaaga agaagctgca aaaacagaaa cagcatccgt
    25321 aaaaaaagaa gtagcgatcg aaaaggaaat cctcgtaagt ccgctgcaag gtaaagtgct
    25381 gccattgg
//
