LOCUS       NZ_CP085682            22388 bp    DNA     circular CON 22-AUG-2024
DEFINITION  Paenibacillus polymyxa strain YS18-2 chromosome, complete genome.
ACCESSION   NZ_CP085682
VERSION     NZ_CP085682.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5840603)
  AUTHORS   Liu,J. and Huang,Y.
  TITLE     Complete Genome Sequencing of Paenibacillus polymyxa strain YS18-2
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5840603)
  AUTHORS   Liu,J. and Huang,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-OCT-2021) Department of Sericulture, South China
            Agriculture University, Wushan, Guangzhou, Guangdong 510642, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. v.3.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 253.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024584565.1-RS_2024_08_22
            Annotation Date                   :: 08/22/2024 06:09:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,167
            CDSs (total)                      :: 5,043
            Genes (coding)                    :: 4,970
            CDSs (with protein)               :: 4,970
            Genes (RNA)                       :: 124
            rRNAs                             :: 13, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 13, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 40 of 73
            Pseudo Genes (incomplete)         :: 41 of 73
            Pseudo Genes (internal stop)      :: 12 of 73
            Pseudo Genes (multiple problems)  :: 18 of 73
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:38:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3993193
            Orig. end                         :: 4015581
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP085682.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22388
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="16"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..22388
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22388
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12388](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12388)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(281..484)
                     /locus_tag="LJR53_RS17245"
     CDS             complement(281..484)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686344.1"
                     /locus_tag="LJR53_RS17245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_031461903.1"
                     /transl_table=11
                     /translation="MISYKPFQKLLIDREIKKQDLLKMTGISSATMAKLNTNEYVSLEV
                     IDKLCAALSCQPGDLLEHIAEQ"
     gene            655..942
                     /locus_tag="LJR53_RS17250"
     CDS             655..942
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014282631.1"
                     /locus_tag="LJR53_RS17250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_126666008.1"
                     /transl_table=11
                     /translation="MHNSLEVLLDSLIHTRIESLYGELTKNNFSYNQFSSERNLYFKQL
                     HEGVPENIQKTLFLYDDAELSVQAILEREIYLQGFKDALHLYNELHISLD"
     gene            complement(1113..1571)
                     /locus_tag="LJR53_RS17255"
     CDS             complement(1113..1571)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LJR53_RS17255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_126665877.1"
                     /transl_table=11
                     /translation="MKKKIAIMLGEFLTNFMKVIIHLPGFQVTITNEVYQSIMKELHGS
                     RIEIEKKIGKAYESLHETSNLLFELEDTLKERTEKLNYLRTEYERYNKLTEIEHSKAVP
                     LINHMDTILERGKKTERWLNFFLGLAAGVITTLLGIIFGPYITDVFIK"
     gene            complement(1705..2358)
                     /locus_tag="LJR53_RS17260"
     CDS             complement(1705..2358)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LJR53_RS17260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_126665878.1"
                     /transl_table=11
                     /translation="MTAQFNFNKLNNIYAEAIASVDKTLIFETQVGKGRFLFMMFLSDE
                     DKDSKDKLFIYLRNTNLIKPVKVYGNHSKGQFEVYIKDELKEALIKELQLNSSSSSFDF
                     KNFLEQLNSSIPQSINRDNKITELRKNRSIISELKVVDEADKTVLKHEVKLPENKKPQD
                     KTLRKLYVYTDGAVEDIAELIQLLKKFNMTVAWTTKDKENNTSSVKALLGKLNN"
     gene            complement(2796..3437)
                     /locus_tag="LJR53_RS17265"
     CDS             complement(2796..3437)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013964.5"
                     /locus_tag="LJR53_RS17265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HNH endonuclease"
                     /protein_id="WP_126665879.1"
                     /transl_table=11
                     /translation="MSINEDVLSEVLSKSARHCCICRQFLPLSIQVHHIIEKSDGGTDD
                     FDNLIPVCIQCHGFIHTNPHMTRKFTAKEQKMSRNDLYEMVSVGKLPATKSMTRNELEV
                     VSSILAETLKNSENKEELSDEAIKLLSATLCEDSNIKINRFSENSVMIIVGNQYFTPRD
                     KFEGQYPKPIIELLSQGLVKSQGDTLEITDKGKKLVTKLVQTTETYTQKK"
     gene            complement(3664..5595)
                     /locus_tag="LJR53_RS17270"
     CDS             complement(3664..5595)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LJR53_RS17270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_244944235.1"
                     /transl_table=11
                     /translation="MKRIKFYSINDILYGRNLLRSRTLIDEYYNEEVDDINDVIELYNA
                     KKYFDNKIYLSDWTPDTIASLEKKINKLFGIVAKFFKTINDDNLLEMYSKVERNYRDDF
                     WELIDKFKVYENITSDCFKIFLSTTSVSLGDLLKSKSITNHYGEIIKDKMLSDPLSSVQ
                     LLLDKYEFKHHREPQAIHFPKQLSSLDKELIISSYLDSEEPNLNYVRLIANIQSSKDKL
                     EISPKVLLKAKRKAEELEKQYFVENSGMPMETSVSFSKSQNEEVKLIYEGQTIAATYST
                     KWIEENRDFPTLLNNFIYLFEFVDLQMRSTIVNKTSEMGVFERHIFISSQNAYNVGFVF
                     EGKNVLSLLQISGYYHQLFSIGIRLEEIIEWFFEDYLLAEFDAHNFKVKMPSVNSPFFE
                     KCTYITPALESVLKQFILFVEDGHIDFELLEIRSEHLVYKNISSLISKKYAYGCGNEFN
                     YLIYLLFSDQCGLGYLERSAESYNNFFELLTNERLNKNEIPSYNLKEIEWLIQKQYLSI
                     DEDEIITFKDYQLALLLYDFYINEVVCYWKCSEYKRKLLDELQDKGMIEFESTLFSRQE
                     TDYINYTLNKSQFNNGLDLRNKYSHIQPNIENDKEIHNQNYLILLRIFILTVIKINDDF
                     CTKRDFKQ"
     gene            complement(5739..6667)
                     /locus_tag="LJR53_RS17280"
                     /pseudo=""
     CDS             complement(5739..6667)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012798.5"
                     /locus_tag="LJR53_RS17280"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="tyrosine-type recombinase/integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKINLLYRDKKTIGGTRRLMRFPFLRNEVNGTRISGKKCAMHWWQ
                     GATAARRLKHTYRKRNAFLRDCKGTKSINDATVQKYALALLEKGLSHAYVNQAISALNF
                     YFRHVLKQPKSAAYVRPKKESKLPDVLSLNEVMRLLKAAKNPKHKAILYLTYTSGLRVS
                     EVVRLRLEDCDRERKVLKVRQGKGRKDRQTLLSEEAFAVVEQYDRGNSQQTGCFQGRGK
                     AAT"
     misc_feature    6716..6729
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.57"
                     /tool="antismash"
     gene            complement(6978..9041)
                     /locus_tag="LJR53_RS17285"
     CDS             complement(6978..9041)
                     /GO_process="GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372332.1"
                     /locus_tag="LJR53_RS17285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_257126128.1"
                     /transl_table=11
                     /translation="MSQNMKKRVFRSSSIANTLAMVLLVIIVVVFATLGTFMYASTQSM
                     LVKQQEAMLQTKTQATVSQFDALFKEKGSLVKQMATNNLFRQYIETTESAETVKTSPHA
                     AETEATLAAIVKAEPSFADAWIAGIAGKGFFLQNDGAVSKPDFDINTRPYFKPAVEADG
                     LYYSEPYKDVNTGNVVMGIFYPIKDSGNQLIGFAAVDIAFKDIPAVMQSYSLGSTGYSI
                     LASKTGDILYHPDQNKVLKEKITESTGDLGEIGKKMIAGESGVQLINDNGERRYIGYAT
                     SKDTGWSVGLTISEQEALSELRTFTWITIGGFAAATILLVVICYITLRYLLRSIPKLLA
                     KIKLIENGDLTVPFDTNSHNEIGQISQGVHNMVQKIQGMLQMVGGSAQVLNQSSHDLQS
                     ISSRTAITMNDTATAINEIANATNYQSIETDNILQKTGALSGQIDEIANDAKTIETMVQ
                     TSAEQSGQGLAVVDQLSKWAEENHNSTQAMSAIIQDIDLSRHEISGIVDTVNQIATQTN
                     LLALNASIEAARAGEQGKGFAVVAGEVRKLAEQTALATQEIYKKVRVIEEKTSVSVEHT
                     VHGLKIAEENARSVEDTKQVFFSINKDLEDLKLRMIQISTNTSKVHKHKDEILQALEII
                     SSTTEENSASTEEVSASTQEQLESFEQVAELSKQLNQLSTKLQDELKQFKVE"
     gene            complement(9326..9865)
                     /locus_tag="LJR53_RS17290"
     CDS             complement(9326..9865)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017428282.1"
                     /locus_tag="LJR53_RS17290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CueP family metal-binding protein"
                     /protein_id="WP_257126129.1"
                     /transl_table=11
                     /translation="MKKGILVASGLVVAALGTYLIAGNIQKEGADKLGTTDIKQLVHDF
                     SAGKATAQSASINSSQLIVNEDHTQPITYDLPDNEFFVSIAPYVEETHPCATHSLTGCQ
                     GEIKNGAFNVTVHDSEGNIIMENAAMKSQPNGFIDLWLPRDKTYRISVNHEGKTAETEF
                     STYEKNDTCITTMQLG"
     gene            complement(10001..12388)
                     /locus_tag="LJR53_RS17295"
     CDS             complement(10001..12388)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007431396.1"
                     /locus_tag="LJR53_RS17295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_257126130.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.4e-43, bitscore:
                     147.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHHMNEKFRADTGYQLAEQKALQYFASLYNQVKDKTYVTSLTEDI
                     HIWKRNHIRPSSWLSFISRNKRKPDTRDYDRYIQWLSYTGKLDDYLKRSVSYIYMRDLG
                     KALDSANTQTRIQRVIADVKRYLLQPTRANRRNQPEFMNIAGVYRWSQKEGIEATVIWL
                     INKLNSVSSHIPEEMDAEHAQRKLIKIIIGVILHVMEEMDEAMSPVERSRRLDEAIRLG
                     YSYGLTYPFIDDLLDSQLLTVQEKEQYSHMIRTALLTGSVPELGDWTGDHMKFIRYIHS
                     ELSDAFEYIKAHQRPDTQQTFFEQSYVFFHSQDIDRDKDLTRANYTNEELYIPVILKSA
                     SSRLIVRSVISAPEDEGFEQRTFYYGIYNQLADDFADMADDMRDGAVTPYTYYLKYHRQ
                     RSDLINPFELYWAVISHLIHNVYDTDAMAREVILDRAINGLKRYKERVGAEKYNEIMGI
                     FASGNPEFNRLIQKMVGKAEDVDFFDKLLRDQMITQLKNDSREKEDFMNTVKTVRDQIN
                     NQLKITKPSGIEAMKEQLIEAANYSLEGDGKRIRPILTWVMGVNEYGLDALAIVPLLRS
                     LEYMHTASLIFDDLPSQDNASTRRGRQTLHQVHNSATAELTGLYLIQKAIGEQASLNQF
                     NTETVLALIQYSARKAEDMCMGQAMDLDSKGKALTLEQLNMMCFYKTGVAFEACLVMPA
                     MLAQAEESEIAALQKFAYHMGIAFQIKDDLLDVEGDTLLLGKPVGQDSDNNNSNFVSIL
                     GYEGASQEMWEHYCLAMEALKEVPRNISFLKHLMNYIVNRDR"
     gene            12567..13136
                     /locus_tag="LJR53_RS17300"
     CDS             12567..13136
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1296: tellurium
                     resistance protein, TerD"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372335.1"
                     /locus_tag="LJR53_RS17300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TerD family protein"
                     /protein_id="WP_025365467.1"
                     /transl_table=11
                     /translation="MSISLIKGQKVDLTKNNPHLSVLKVGLGWDPMRGRSMDIDASALL
                     LNENGKLTQTKNLVYFGNKNSPCGAVVHSGDNLTGHGDGDDEVITVSLQQLPPEVHRVV
                     FIVNIFRFFSFGRRKDFSMVNNAYIRVLDASQDEEILRYNLTEDYKGMCSIRVGEVYRY
                     GGEWKFGAIGEGSTITSLNELVKTYE"
     misc_feature    complement(12593..12611)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.85"
                     /tool="antismash"
     gene            complement(13180..14100)
                     /locus_tag="LJR53_RS17305"
     CDS             complement(13180..14100)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688151.1"
                     /locus_tag="LJR53_RS17305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_257126131.1"
                     /transl_table=11
                     /translation="MLHLDKQLHSFVDISNNIEGFEIVSTQFGPDGRVYILLIDKVPER
                     VRGMFTPASLKEKRTYKVLILDDHIQEVCLEGQQFNYHYVQPLQDYLLLVGARCHYYGP
                     DQYDLNGKIIDYEGRTVNELLLGDGIQSVQVTKEGTIWTSYFDEGIFGNYGWNEPVGSS
                     GLVAWNKEGHKIYENQAADIHDCYALNVISEQEIWFYYYSDFSLGYISGSDRTNITFVN
                     PRISGCSGVATDGYHFLFDGGYGKNGQYVLKKNVKPGNLSKGQHIRFLNDDQKFLQPHE
                     QDFRKDRLLLREGSLLYQAAVEEIV"
     gene            complement(14307..15248)
                     /locus_tag="LJR53_RS17310"
     CDS             complement(14307..15248)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372337.1"
                     /locus_tag="LJR53_RS17310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_257126132.1"
                     /transl_table=11
                     /translation="MALNKDRFLGCLAGLAVGDALGTTVEFSSPGTFEPVTDIVGGGVF
                     GLKAGQWTDDTSMALCLAQSMVQKDSFDPADQMRRYTNWYHLGYMSSTGTCFDIGGATR
                     AALHRFEATGDPYSGSVDPMTAGNGSIMRLAPVAMAYANRPEEAVMYAELSSRTTHGAV
                     ESVEACAVLASILVAGLRGADKESMLSPDVCYRWRRQEQSAYSAAIEEIIQGSYKHKEP
                     PEIQGSGYVIRSLEAALWAFHHSASFEEGALLAVNLGDDADTTGAVYGQIAGAYYGLSS
                     IPSHWREKLAMKETIDELTEALWQKADKGQTL"
     gene            complement(15332..16420)
                     /locus_tag="LJR53_RS17315"
     CDS             complement(15332..16420)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688153.1"
                     /locus_tag="LJR53_RS17315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_257126133.1"
                     /transl_table=11
                     /translation="MPFSHVSLPDLPSSIGRLTAIHPVKGGSQGSITLLALNTQAELWR
                     LELRSGSAELCICICIPDFNPMQPVQMVTSPDGKYVAISNRFGRHAAVYDLVYAQEKMQ
                     LSRDEYHYDKSMFPLAFVHQDGMCILVHGTEWNRLDLTDIETGRLLTARPSPVYNNESK
                     DEHYLDYFHGRLLASPEGKWMADTGWVWAPLGVVRTWSLSDWLLNPWESENGPSVRHLW
                     QTIDWDGPVCWTGPDTLAVWGQMDADLLEEEDWGEEGVEPAVVLFDMTQPGYRRVLSAI
                     PPLNCKPDEYGIYPYPQADMTACGDRLFLWGKEVPLQVWRLSSGVREYIDTERFPLIYH
                     QEAGIFIELNPDSGCTALSYDE"
     gene            complement(16420..17415)
                     /locus_tag="LJR53_RS17320"
     CDS             complement(16420..17415)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372339.1"
                     /locus_tag="LJR53_RS17320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_257126134.1"
                     /transl_table=11
                     /translation="MSFSKIYDYKLKAYFNERISDLNHEDLFYSYPDQEQNLRILTLNI
                     NEQDHISLVRWHDLFDRSLFTKMDHPILSVTDAERLIRLLALIFNMFDIHKDVAYSRKN
                     LCCFYYQYQVSHLAERGNEFTFAQDRLFFLHQLLFELGLGDDIYDRLTIENNKLLYSME
                     DGQQYDLHILIDILHEHINKNKMDMDTRATLRKIKNLQGQLVNFILGSHDVYDFPYDDF
                     NKSFAEAKIFIQAYNSNKNRALEVLIDCINEHQSPTEQFISHLILMNYSYFVLKSNPSE
                     ITYFKLFCKKKPGVFMKVLTALLELGFFVDNTIFANAGIPYDLSRVKGVK"
     misc_feature    complement(17497..17510)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.61"
                     /tool="antismash"
     gene            17597..18247
                     /locus_tag="LJR53_RS17325"
     CDS             17597..18247
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017428289.1"
                     /locus_tag="LJR53_RS17325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_257126135.1"
                     /transl_table=11
                     /translation="MKQLNEALTRFVHQQNLYNEAYGLFQDHDIQPRSESITDCWDSRI
                     PLSPELAYMYSHYEMIDAKAAGTHKLKNAAVEVGDAAVLFFVAPEHLYRQQLGYRFITS
                     GELVQESSSWPYHHVVIATFNDDPLIVDTSAPDSPVYAAIEGGAAQQIADSLANFFTAL
                     SILIEGACTFKGELVDEDTYETKAAYIEHVKPLLHHLLGENQTTYLLKYLSFC"
     gene            18282..18851
                     /locus_tag="LJR53_RS17330"
     CDS             18282..18851
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017428290.1"
                     /locus_tag="LJR53_RS17330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1697 domain-containing protein"
                     /protein_id="WP_257126136.1"
                     /transl_table=11
                     /translation="MIYIALLRGINVGGNNKIEMKKLKQTFEHAGMGHVTTYINSGNII
                     FSSQERSNQELSLVLEQAILEDFSLPIRVIVRNMKEIQSIMEALPNEWANDTQMKSDVM
                     FLWDEINDITVLDKLPLKPGIGHVIYTPGAVLFSVSKEQVTKSGLTKLVGTKLYQQMTV
                     RNVNTTRQIYKLMQMAEQEELRNTSS"
     gene            complement(18956..20809)
                     /locus_tag="LJR53_RS17335"
     CDS             complement(18956..20809)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LJR53_RS17335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_126665890.1"
                     /transl_table=11
                     /translation="MNPILFFAHNLLLLNLIDEHNNMEFEQTIIPGIIDRIAKDYERLD
                     FIYSNGLEEYCTDDDRFTDFYFSSDYTDSYNLKLRQILDLNEQYNSQKLRDVIEKLKVF
                     FINSLLKDDRYALSDEEKYGVPKIVNKLLKQGFEIPAMKELLDGYRSKINFLKFYIVFY
                     EFRDIYGQDFDCYLQENYNEISDKIIWLIGDDYDFYASDDLEIEIENLLFGDAPEAIEL
                     YNVQVKKESLKAMRILEKTLNWDGYSVKWNRIHSNFEKITNHNPNKNKVEFHRDDIFVE
                     ETSERDFMEELLPYIHWDDQDSWDSLINLAGIVGSEITIMDRVQEDLFMGKSKWKGTYY
                     SNDPLFLAKIVDEYKRGNRIENQIRNFFDNMFSSIDCSEYEILTKIAVAAQEHNEMYFN
                     RDNLKHWLNISNEDWNLIKESSYLGHNNGWLYFIASEIQVYLLCKNINDHSYNKVKILS
                     LIDWIINESEFHTYIYNVFCILVEFFADESKNFFLESIQSFTDHMKELNGTELLTFGLS
                     SIYTLQEMNDNQEVTSTIKNWTLLRFLEMLEVEFNEVTSDLSYDLFQKIATNKYETECA
                     IDYEYCIAHPEKLAPLLNTSSVEQMIKDDLTKIDNFIEQYF"
     gene            complement(20931..22367)
                     /locus_tag="LJR53_RS17340"
     CDS             complement(20931..22367)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF045198.2"
                     /locus_tag="LJR53_RS17340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_126665891.1"
                     /transl_table=11
                     /translation="MKNNYDFHALLDDVEFEALAIDIVRVRENLEPNVFRRYPKGRDGG
                     IDGYRYSDNTIIQAKCYKNDFNILKGNLKKEVLKLRNLKPSRYILVTSVGLNKEQQREI
                     MDLFKGYIHSDKDIIGRIELNEYLTDPKFSFIQIKYNNLWTPSTVVFEHILENIILRGP
                     NNFNQFHLNEMKNNVEYYIKTKAYHESLDIMDSHNCLLVYGEPGIGKTVLGFNIAFHYL
                     MQNEELDLFFTDTIEDVYKFYRSDKKQLFVVDDFLGVNYVNNQIKNGESKIYRMLKSII
                     SGNNHKIVLISRKNILFEGMKLLQELKVIIQNMSVELSSTSLENSDKMRICWSILKKSN
                     LQYSLLHSIVIVSDKIINHDNYNPRFINDAIHLLSKIKHDGMYPGKILLETLKNPNEIY
                     ERMYNHLHETSKSAVYLGICMAIFGYPVELNILRKCYGDLQESLPWQEWQSFDEALGQL
                     SASFCFVRDMNFIRTLTGID"
ORIGIN
        1 gtgaaaaatt gcgggctaaa ttttatcgct aaaaagtctt tgagatgacg tgtactatca
       61 ccgaaaatct tagttataac gatctgagta tctctatgcc attttttata ttcgggagaa
      121 aatcttgtaa agctttgtaa ttgaccaagc tctcttttct gtctgtctaa ttgttcaatt
      181 gcttcttttg tgttcataat gaatcctttc attaagtatt taagcaattt ccgataatgt
      241 tcctgtattc atgacccccg aagggttgtc tgctaatctg tcattgttct gctatatgct
      301 ccaataaatc tcctggctga caacttaaag ccgcacataa tttatcaatc acttctaatg
      361 acacatattc gttcgtattg agtttcgcca ttgtagcaga cgagatacct gtcattttca
      421 ataaatcctg cttcttaatc tccctgtcga tcaataattt ttgaaaaggt ttataactaa
      481 tcatctgata ttcctttcac acatcaagtg aacttttctt taattatatg aaagtatatt
      541 ttctttatca aaaacatctt taacatgttt gacttaatta ttttatatgt taaaattata
      601 tttaataagt tgaactttta ttcacaaaat caaatgcatt ggatggtgtt tagtatgcat
      661 aattctttag aagtcttact tgattcactc attcatactc gaattgaatc tttatatggc
      721 gagcttacca aaaacaactt cagctacaac cagttctcat ccgaacggaa tctctacttc
      781 aagcagttac atgagggagt accggagaat atacagaaga ccctattcct ttacgacgat
      841 gctgagcttt ctgttcaagc tattttagaa cgtgaaattt atttgcaagg ttttaaggac
      901 gctcttcacc tgtataacga attacatata tctttagatt gagagccttc tggctctttt
      961 tcatttttga ttctgttgta taacgtttct gtattcatga accccaacgg ggttgttcgc
     1021 tgaaattcct ctccaaaatt catcccgcag accaaggctc cccaggagcc gcagcttaaa
     1081 tattatgtta tgggatgtgg ctgttcatcg aattacttaa taaatacgtc tgtaatatat
     1141 ggcccaaaaa tgatccccaa tagtgtagta ataacaccag cagctaaacc cagaaagaag
     1201 ttgagccacc tttccgtttt ctttcctctt tctaagatag tgtccatatg attgataaga
     1261 ggtacggcct tactatgttc tatttcagtt aatttgttat atctctcgta ttcagttcta
     1321 aggtaattca atttttcggt tcgttctttc aaagtatcct ccaattcaaa aagtaaattt
     1381 gaagtttcat gtaatgattc gtatgccttc ccaatctttt tttctatttc gattcttgat
     1441 ccatgtagtt ctttcattat tgattgatat acttcatttg ttattgttac ttggaacccc
     1501 ggtaaatgta ttattacctt cataaaatta gttaaaaatt cccctaacat aattgcaatc
     1561 tttttcttca ttctttgtta tcgcccttta tatattattt acagccattt cctataaagt
     1621 tcctgtattc acgacccaac gtaggctggg tggccggcga atgccggacc cagagcgtag
     1681 aatattatgt tatatgaagt tcgtttagtt gtttagctta cccaataatg cttttacact
     1741 tgaagtgtta ttttctttgt cttttgttgt ccatgccaca gtcatattaa atttcttgag
     1801 cagttgaatt aactcggcta tatcttcaac agctccatca gtataaacat ataattttct
     1861 taaagtttta tcttgaggct ttttgttttc aggaagtttc acttcgtgct ttaacactgt
     1921 tttatcagct tcatctacta cttttaactc gcttattatg cttctatttt ttcttaattc
     1981 agtaattttg ttgtcacgat ttatgctttg aggaatgcta ctattaagct gttcaagaaa
     2041 gttcttaaaa tcaaaagaac ttgaacttga atttagctgt aattccttta tcagagcttc
     2101 tttcaattca tcttttatat atacttcaaa ttgaccttta ctatggttac catatacctt
     2161 tacaggcttt ataaggttgg tgtttctcag atatataaat aatttgtctt ttgaatcttt
     2221 gtcttcatct gataaaaaca tcataaataa gaatcttcct tttccaactt gggtttcaaa
     2281 gattaatgtt ttatcaaccg atgcgatagc ctctgcataa atgttattca atttattaaa
     2341 attaaattgt gctgtcattt ctgttcctct cattttttag gatttcatat aacgttcccg
     2401 cattcacgac gtctcagcgc cttaagaacc gaaggttcag atgccgcttg cggcagttag
     2461 gcggtgggat gtgtccggtg aatttacttc cccgaaatgc cccttacggt cagggtcgag
     2521 cttgtctcga cttgccgcgt tgaatgtgat gttaactgat gttcctgcct tcgtagctaa
     2581 gcttactagt tttttttatt cagatttcaa tctaggtgaa tcatataaca tagcatttcc
     2641 agggacatct tgaaagataa aaccaaattt ctgctgagtc caaatgagaa ataaaccctt
     2701 gttttgtccg cattcaggac aacaaattga actactatta tgtttgtctt tatcccatgt
     2761 gcatataata aaatgcaaac tacaatttaa gcactttatt ttttttgcgt ataagtttct
     2821 gttgtttgaa ctagttttgt tactaacttt tttcctttat cagtaatttc aagagtatct
     2881 ccctgggatt taaccaaacc ttgagataac aattctatta ttggttttgg atattgtccc
     2941 tcaaacttat ctcttggagt aaaatactga tttcctacaa taatcattac tgaattctca
     3001 gaaaatctat ttatcttgat atttgagtct tcacatagtg tggcagacaa tagttttata
     3061 gcttcgtcac ttagttcttc tttgttttcc gaattcttca aggtctctgc caatattgaa
     3121 gaaaccactt cgagttcatt tctcgtcatt gatttagttg cgggtaactt cccaactgaa
     3181 accatctcgt ataaatcatt cctactcatt ttctgctctt ttgcagtgaa tttccttgtc
     3241 atatgaggat ttgtatgtat aaatccgtga cattgaatac acactggaat caaattatca
     3301 aaatcatctg ttcctccatc acttttctct ataatgtgat gcacttgaat gctcaaaggc
     3361 agaaactgcc tacaaataca acaatgtctg gcagattttg ataatacttc tgataatacg
     3421 tcttcattaa ttgacatggc tattcccctc ctagaaatac tattatttat ttttatactc
     3481 ttgctttttt agtttttata attttgcagg aatctcagtt aacgtttctg tattcatgaa
     3541 ccccaacggg gttgtctgct gaaatatctc tccgaaattc ataccgcaga ccaaggctcc
     3601 ctaaggagcc gctgcttgaa tattatgtta tgtgacgttt ggaccatcct cgaatcactt
     3661 taatcattgt ttgaaatccc ttttcgtaca aaagtcatca tttattttta ttacagttaa
     3721 aataaatatt ctcaataaaa tcaaataatt ctgattatga atttccttat cattctctat
     3781 attcggttga atgtgactat atttgttccg taaatctaat ccattattaa attgcgattt
     3841 attaagagta taattgatat aatctgtttc ctgtctagaa aagagagtgc tttcaaattc
     3901 aatcattccc ttatcttgta actcatctag tagcttacgc ttatactctg aacatttcca
     3961 atagcacact acttcattaa tataaaaatc atataaaagt aaggctagtt gataatcttt
     4021 aaaagttata atttcatctt cgtcaataga taaatattgt ttctgtatga gccattcaat
     4081 ttctttcaag ttgtaactcg gaatttcatt tttattcaat ctttcatttg taagtaactc
     4141 aaaaaagttg ttataagact cagctgatct ttcaaggtat cctaatccac actgatctga
     4201 aaaaagtaag taaattaaat aattaaattc attcccacaa ccataggcat atttctttga
     4261 tatcaaggat gaaatatttt tgtagacaag atgttcagat cgaatttcaa gtaactcaaa
     4321 gtctatatgt ccatcttcaa caaataaaat aaattgctta agaactgatt ctaaagcagg
     4381 tgtaatataa gtgcatttct caaaaaaagg agaatttact gagggcattt tcactttaaa
     4441 gttgtgtgca tcaaactctg caagcaaata atcttcaaaa aaccattcaa tgatttcttc
     4501 tagtcttatc ccaatactaa agagctgatg ataataacct gatatttgga gtaatgacaa
     4561 aacgttctta ccctcaaata caaaaccaac attatatgcg ttttgagatg aaataaaaat
     4621 atggcgttca aacactccca tctcgcttgt cttattaact attgtacttc tcatttgtaa
     4681 atcaacaaat tcaaaaagat atataaaatt attaagtaaa gttggaaaat ccctattttc
     4741 ttcaatccat ttcgtgctgt acgttgcagc tatggtttga ccttcatata tcaacttcac
     4801 ttcttcattc tgacttttcg aaaaactcac acttgtctcc attggcattc cagagttctc
     4861 tacgaaatat tgcttttcta gttcttctgc ttttcgcttt gcttttaata agactttggg
     4921 tgagatttca agtttatctt tactgctctg tatgttagca ataagccgta catagttcaa
     4981 attaggttct tcactatcca aatagcttga aataattaat tctttatcta gactacttaa
     5041 ttgtttcgga aaatgtatgg cttggggttc tctatgatgt ttgaattcat atttatccaa
     5101 aagtagttgg actgatgata agggatcaga caacatttta tctttaatta tttcaccata
     5161 gtgattcgtg atgcttttag actttaataa gtctcccaaa gatacacttg ttgtactcaa
     5221 gaatatcttg aaacagtcag atgtgatatt ctcatatact ttaaatttat ctataagttc
     5281 ccaaaaatca tctctataat ttctttcgac tttactatac atttctaata agttatcatc
     5341 attaattgtc ttaaagaact tagcgactat tccaaagagt ttattaattt tcttttccaa
     5401 actagctata gtatcaggtg tccaatcact aagatatatt ttattatcga aatacttttt
     5461 tgcattataa agttcaatta catcattaat atcatctact tcttcgttgt aatattcatc
     5521 tatcaatgtt cggcttctca ataaatttct tccatacaga atatcattta ttgaatagaa
     5581 ttttattctc ttcatgtaag ctccttatct gtaactggct tttgccctaa tgtcacataa
     5641 tgtcttattt acgaacttcc gaaagaatgt tctcttcgtc atattcacga acttcgtgaa
     5701 tcctgcactt tgttcctgat tcccgcactt tctgcgtttc aatcctccag cccgctcatc
     5761 cgatccaacg gactttgaat ccgcccaatg tcccgtctgc tcacatgtgt ataccgctcc
     5821 gtcgttcgca cactctgatg ccctagcagc tcctgaatat agcgaagatc aatcccattc
     5881 tccagcaagt gggtcgcaaa gaaatgcctt agcgaatgga tactcacctg tttgcgaatg
     5941 cccgcttcag ccagcgcttt ttcaaacact ttctgcgctg aacgttccgt caggtggcgg
     6001 ccttccctct gccctggaaa cagccagtct gctggctgtt ccccctatca tactgctcga
     6061 ccaccgcaaa agcctcttcg gatagcagcg tttgccgatc cttcctgccc tttccctgac
     6121 gaactttcag tactttccgt tcacggtcgc agtcttcaag acgcaacctc accacttcgc
     6181 ttacccgcag cccggatgta tacgtcaggt acagaatagc cttatgcttt ggatttttcg
     6241 ctgctttcaa cagacgcata acctcattca gggacagcac atctggcagt ttactctcct
     6301 ttttcggacg aacataggcg gcggatttgg gctgctttag cacatggcga aagtaaaaat
     6361 tcagcgcgct gatcgcttgg ttaacataag cgtgcgaaag gcctttttcg agcagcgcca
     6421 acgcatattt ttgcaccgtc gcatcattta tgctcttcgt tcccttgcaa tctcgcaaaa
     6481 aagcgttccg tttgcgatat gtatgcttta atcgtcttgc tgctgtagcc ccttgccacc
     6541 aatgcatcgc gcatttcttg ccgctgattc gggttccatt cacctcgttc cgaagaaaag
     6601 ggaaccgcat cagcctacgc gtcccgccga tcgttttttt atcccgataa agtaggttta
     6661 tcttcatctc acttgcctcc ttagtatatc agccgttcaa aaaattggaa atctaatttt
     6721 acacaaaaaa agggacttaa gacgggtatt catcttaaga acctgattct ttcagagtaa
     6781 attattgatc cttaaagttc aattttcatc atcataaagt gtcttgcctt tacttatcca
     6841 gttcctctgt cacatcacca cagaaacaaa agaatagccc gattatgttt ttaagaaaat
     6901 aaggataagc cgctaaaaag cccgcgctgc acgcgggctt tgctgtatat aagtcaaaat
     6961 catgcctagt agacttgtta ctccacctta aactgcttta attcgtcttg cagcttagtg
     7021 gacaattggt ttaattgttt ggatagttca gcaacctgtt cgaagctctc caattgttcc
     7081 tgcgtgctgg cgctaacctc ttcggttgaa gcggaattct cttcggtggt agaagagatg
     7141 atctctagcg cctgcaaaat ctcatcttta tgcttgtgga ctttggaggt gttggtgctg
     7201 atctggatca ttcgcaattt caaatcttcc aaatccttgt taatactaaa gaacacttgc
     7261 ttcgtgtcct ccaccgatct ggcattttct tctgcaattt tcagaccgtg aactgtatgc
     7321 tcaaccgata cactggtttt ttcttcgatg acacggacct tcttgtagat ttcctgtgtc
     7381 gccagcgccg tctgctcagc cagcttgcga acctccccgg caaccacggc aaaccctttg
     7441 ccctgttctc ctgcacgtgc agcttcaatg gaagcattga gcgccagcag gttggtttgt
     7501 gtggcaattt ggttgaccgt atccacgatg cccgaaatct catgacggct cagatcaata
     7561 tcctgaataa tagccgacat cgcttgtgtg gaattatgat tttcttccgc ccatttggat
     7621 agctgatcta ctactgcaag cccttgtccg ctttgttcgg ctgaggtttg caccattgtt
     7681 tcgatggttt tggcatcatt ggcaatttcg tcaatttggc cggataaggc tccggttttt
     7741 tgtaaaatgt tatctgtttc gatggattgg tagttcgttg cattggcaat ctcattaatt
     7801 gctgtcgcag tatcgttcat tgtaattgcg gttctggaag aaatggattg caaatcatga
     7861 gaagactgat tcaacacttg agctgagccg cccaccattt ggagcatgcc ttgaattttt
     7921 tgaaccatat tgtgaacccc ttgagaaatt tgcccgattt cgttatggga attcgtatca
     7981 aacggaacgg tcaaatctcc attttcaatc agcttgattt tggcaagcaa tttcggaatg
     8041 gatctcaaca ggtaacggag cgttatataa cagattacca cgagcagaat ggtggctgcg
     8101 gcaaaaccgc caatcgtaat ccaggtaaag gttcttaatt ctgagagcgc ctcttgttca
     8161 gaaatggtta agcctacgga ccatcctgta tctttgctgg ttgcataccc aatgtagcga
     8221 cgttcgccat tatcattaat gagctgtact ccagactcgc cagcaatcat tttcttaccg
     8281 atctcgccaa gatcacctgt gctttcggta atcttttctt tcagcacttt attttgatca
     8341 gggtgataca aaatatcacc tgttttggac gcaagaattg aatagcctgt gcttccaagc
     8401 gaatagcttt gcataacagc agggatgtct ttgaaagcaa tatcgacagc agcaaatccg
     8461 attaattggt taccgctatc cttgatcgga tagaaaatgc ccatgaccac attccccgta
     8521 ttgacgtcct tatagggttc agagtagtat aaaccgtctg cttcaacagc tggcttgaag
     8581 tatgggcgtg tattgatatc gaaatccggc ttggaaacag caccatcatt ttgtagaaag
     8641 aagcctttac cagctattcc cgcaatccaa gcatcagcaa atgatggctc tgcctttaca
     8701 atcgctgcca gagtcgcttc ggtttccgca gcgtgtgggg aagtttttac cgtttcagct
     8761 gattcggtgg tctctatata ctgccgaaaa agattatttg ttgccatttg tttgacaagt
     8821 gagccctttt ccttaaataa cgcatcaaat tgactgacgg tggcctgcgt cttggtctgg
     8881 agcatggcct cttgctgctt gacaagcatg ctttgcgtgc ttgcatacat gaacgtcccc
     8941 aaggttgcaa agacgacaac gataataact aacaagacca tggccaacgt gttggcgatg
     9001 ctggatgatc tgaatacgcg cttcttcata ttttgtgaca tgctgccatc tccccgagga
     9061 atattgagcg aaaagctctt agataatatg tcggaagttt gcagctgttt taataggttt
     9121 ttagtataca caatttaaag ttttgctatc tgattcctca tagatttcct cccaacccgt
     9181 tcagtaactc cagcaaaaga ttagggcagc ataaagagcc tccgtcagac gcaggctctt
     9241 ttctaaaaaa gctatgaaca cgcgaggttt tgcagactta aagcgttcga gcgatctgta
     9301 agctcacccc cattattctc tgtcgttaac ccaactgcat cgttgtgata catgtatcgt
     9361 ttttctcata tgtagagaat tccgtttcgg ccgttttacc ttcatggttc acactaatgc
     9421 ggtaggtttt atctcttggc agccatagat caataaaacc attgggttgt gatttcatgg
     9481 cagcattctc catgatgata ttcccttcgg agtcgtgaac ggtcacattg aacgccccat
     9541 tttttatttc gccttggcaa ccggttagac tatgagttgc acaaggatgg gtctcttcta
     9601 catatggcgc aatcgaaaca aaaaactcgt tgtcaggcaa atcataagtt atgggttgtg
     9661 tatggtcttc gttaacaatt aactgactgg aattaatgga ggcggattgg gctgttgcct
     9721 tgcctgcgct gaaatcatgc accaattgct tgatatctgt tgtcccgagc ttgtccgctc
     9781 cttctttctg aatatttcct gcaatcagat acgtgcccaa tgccgcaaca accaaccctg
     9841 aagcgaccaa aattcctttt ttcatctgga gttcatctcc ttgtccgttt taaatcatta
     9901 taagggagaa cgccccgtaa cggataaaat acggtactga agtcaccaga tattcacatc
     9961 tttgcttgtt tattcagaca tatctggggc acaattcttt ttaacgatcc cggttcacaa
    10021 tataattcat cagatgcttc aaaaaagaga tattgcgtgg cacctctttt aatgcttcca
    10081 tggcaagaca gtagtgctcc cacatctctt gactggcacc ttcgtaacca aggatggaca
    10141 caaaattcga attgttgtta tccgaatcct gacccacagg ttttccaagt aagagcgtat
    10201 ctccttccac atcaagcaaa tcatctttga tctggaaagc aatccccata tgataggcga
    10261 atttctgcaa agcggcaatc tctgattcct cggcctgtgc gagcatggct ggcataacga
    10321 gacaagcctc gaacgccact cctgttttgt aaaagcacat catattcagc tgctccaagg
    10381 tcaaagcctt tcctttggaa tccagatcca tcgcctgacc catacacata tcctctgcct
    10441 tacgggccga gtattggatc aaggcaagta cagtctcagt attgaactgg ttcagtgatg
    10501 cttgttcccc gatggccttc tggatcagat acagaccggt taattccgca gtagcgctat
    10561 tgtgcacctg atgtaatgtc tgacgtcctc tacgggtaga cgcgttatcc tgggaaggca
    10621 aatcatcaaa aatcagggag gctgtatgca tatattccaa tgatcttaga agaggcacga
    10681 ttgccaatgc gtctaagcca tattcgttca cacccatgac ccaggtcaat atagggcgta
    10741 tccttttccc atccccctca agactataat tggcagcctc aataagctgt tctttcatgg
    10801 cctcgatccc agaaggcttg gtaattttca attggttgtt aatctggtcc cggacggttt
    10861 tgaccgtatt cataaagtct tctttttctc ttgaatcatt tttcagttga gtaatcatct
    10921 gatcccgaag cagcttatcg aagaaatcta catcctctgc tttgcccacc atcttctgga
    10981 tgagacgatt aaattcagga tttccggatg caaaaatccc cattatttca ttgtactttt
    11041 ctgcacctac ccgttcttta taacgtttga gtccatttat tgcacgatcc agtatcacct
    11101 cgcgagccat agcatccgtg tcatacacgt tatgaatcaa gtgagagatg accgcccagt
    11161 atagttcgaa gggattgatc aaatccgatc tctgacgatg atattttaaa taataggtat
    11221 agggtgttac cgcaccgtct ctcatatcgt cagccatatc tgcaaaatca tcagcaagct
    11281 ggttatagat accataatag aatgttcgtt gctcaaaccc ttcatcctca ggagcactaa
    11341 tgacggaacg gacaatcaag cgggaagaag cagattttaa aataacgggt atataaagtt
    11401 cttcattggt gtaattagct cgtgttagat ccttatcccg gtcgatatct tgagaatgaa
    11461 aaaaaacata ggactgctcg aaaaaggttt gctgtgtgtc tggccgctga tgtgccttaa
    11521 tatactcaaa agcatccgag agctccgaat ggatatagcg aatgaacttc atatgatcgc
    11581 cggtccagtc gcccagttct ggcacagatc cggtaagaag cgcggtacgt atcatatggg
    11641 aatattgttc tttctcttga acggtcaaca gctgagaatc gagcagatca tcaataaaag
    11701 gataagtcaa cccataggaa tacccaagcc taatcgcttc atccagtctg cgcgaacgtt
    11761 caacaggtga catggcttcg tccatttctt ccatcacatg cagaataacc ccaatgatga
    11821 ttttaatcag tttgcgctgg gcgtgctctg catccatttc ctcgggaata tgagaagata
    11881 cagagttaag cttgttgatt agccagatta cagtggcttc gatcccttcc ttttgagacc
    11941 accgatacac cccggctata ttcataaact ccggttgatt tcttctatta gcacgggtgg
    12001 gttgaagcaa atatcttttc acgtcagcaa taacgcgctg aatccgggtc tgtgtgttcg
    12061 cagaatctag agccttgcct agatccctca tgtaaatata agagacactt cgcttcagat
    12121 aatcatccaa tttgcctgtg taactcagcc attgaatgta tctgtcataa tcccgagtat
    12181 ccggctttct cttattccgc gaaatgaagg ataaccatga agaaggacgg atatgattcc
    12241 ttttccatat atggatatct tctgtaagag aagtcacata agtcttatcc ttgacctgat
    12301 tatagagtga tgcaaaatac tgaagcgcct tctgctcagc cagctggtat cctgtatcgg
    12361 ctcgaaattt ttcattcata tgatgcatta cctcaacttc tcattttgtt taaacatggt
    12421 tgcatttctc cctgagggaa cgaatttgga tcatgttttt atctttatac ggaaaaaaat
    12481 ctgtgaagtt acgaatagat tatatccttc tatatatatg ctacaatttc agagtagaac
    12541 aaaaataatg atagggaggc ataacgttga gtattagtct aattaaaggg cagaaggtag
    12601 acctaaccaa aaataatcca catttatccg tgctcaaagt agggcttgga tgggacccta
    12661 tgaggggcag atccatggat attgatgcat cagcactgct tcttaatgag aacggcaagc
    12721 tgactcagac gaaaaatcta gtatatttcg gaaacaaaaa tagcccttgc ggggccgtcg
    12781 tacatagtgg tgacaacttg acaggacatg gtgacggtga tgatgaagtc attactgtat
    12841 cccttcaaca actaccacct gaagtgcata gagtcgtatt tattgtgaat atattccgtt
    12901 ttttcagctt tggtagacgt aaggatttca gtatggtgaa caatgcttat attcgagtat
    12961 tggatgcgtc gcaagatgaa gagattctcc gatacaattt gacagaggac tataaaggga
    13021 tgtgtagcat ccgtgtaggt gaagtatacc gctatggagg ggagtggaaa tttggtgcta
    13081 ttggggaagg cagcaccatt acctccctga atgagcttgt caaaacgtat gaataagtat
    13141 ttttggtgtt aaggaaaaac ccacgtctga cgtgggtttt tatactatct cttcaacagc
    13201 cgcctgatac agcagagaac cttcacggag cagcaggcgg tcttttctga aatcctgttc
    13261 atgcggttga aggaactttt gatcgtcatt taaaaagcga atgtgttgtc ctttgctcaa
    13321 gttgcctggc ttcacattct ttttcaagac atattgtcca ttcttgccat acccgccgtc
    13381 gaacaaaaag tgatacccat ctgtagccac cccggagcag ccggaaatcc tcggattcac
    13441 aaacgtaata ttcgtacggt cgctaccgga aatataccct aatgaaaagt ctgaatagta
    13501 ataaaaccag atttcctgtt cgctgatcac gttcaaagca tagcaatcat gaatatctgc
    13561 cgcttggttc tcatatattt tgtgtccctc tttattccag gcgacaaggc cggaggaccc
    13621 cacaggctca ttccaaccat aattcccgaa tataccttca tcaaaataac tggtccagat
    13681 cgtaccttct tttgtaacct gaacactctg gataccgtct ccaagcagta gttcattcac
    13741 agtacgacct tcataatcaa taattttacc atttagatcg tattgatcag gtccgtaata
    13801 atggcatcgt gctccgacga gtaacaaata atcttgtaga ggctgtacat aatgatagtt
    13861 gaactgctgc ccctccaaac acacctcttg aatgtgatcg tctagaatga gtaccttgta
    13921 agtacgtttc tctttaagag aggcaggcgt gaacatcccc cgcactcgtt ctgggacttt
    13981 atcaatgagc aaaatataca cgcgtccatc aggaccaaat tgggtcgaaa cgatctcaaa
    14041 cccttctata ttattggaaa tatcgacaaa tgaatgaagc tgtttatcta gatgtaacaa
    14101 tgtagttcct cctctaaaag atcagtaaag tgaagtttta tttgtattgg atttcatttt
    14161 gtcataacga caagtaactg aggagggtgg aagtatggcg atatgggtag taatcccaag
    14221 agatgagtca tcggcaaaat atagcgaaca aaaaaagctg ggatctgctt cataagaaaa
    14281 gcaacccagc ttgatagatg ttccccttag agtgtctggc ccttgtcggc cttctgccat
    14341 aaagcctcag tcagctcatc aatcgtctct ttcattgcca gcttctcgcg ccagtgactc
    14401 gggatactgc ttagcccata ataagcccct gcaatctggc cgtacactgc tccggtcgta
    14461 tctgcgtcat ctcccagatt tacggccagc agtgccccct cttcaaatga agccgaatgg
    14521 tgaaatgccc acagcgcagc ctcaagggaa cgaataacat aaccgcttcc ttggatttca
    14581 ggcggctcct tatgcttgta agatccctga atgatttctt caatggctgc cgaataagct
    14641 gactgttcct gccgccgcca cctatagcag acgtcgggtg ataacatgga ttctttgtcc
    14701 gctccccgca gacctgccac aaggattgaa gcaagcacgg cacaggcctc cacactttcg
    14761 actgctccat gggtggtgcg cgagctcagc tcagcgtaca ttacagcttc ttccgggcgg
    14821 ttcgcatagg ccatggcgac aggtgcaagc ctcataatcg aaccattacc agcagtcatg
    14881 gggtcaacgg acccgctata tggatctcca gtggcttcga agcgatgcag tgctgctctc
    14941 gtcgcaccac cgatatcaaa gcacgttccc gtgctgctca tatatcctag gtgataccaa
    15001 ttggtgtagc gacgcatttg gtctgctgga tcaaagctat ccttttgcac catactctgc
    15061 gccaaacata acgccataga cgtatcgtcc gtccactgtc ctgccttcag cccaaataca
    15121 ccaccgccta caatatccgt tacaggttcg aatgtgcctg gactgctaaa ttctactgtg
    15181 gttcccaaag catcacctac ggccagtcca gcgagacatc ccaaaaaacg atccttgtta
    15241 agtgccattt tgatgtacac tcctttgtaa ttgttatagc taatgcatat atttccatat
    15301 cactaggaag gagaaatatc cggtacgcca tttattcgtc gtagctcaag gctgtacaac
    15361 cgctatctgg atttaattca atgaaaattc ctgcctcttg atggtaaatg agtggaaatc
    15421 gctccgtatc tatatattcg cgcacaccgc ttgaaagccg ccatacctga agcgggactt
    15481 cttttcccca taagaataat cggtcgccgc aagcggtcat atccgcttgg ggatatgggt
    15541 aaatcccgta ttcatcaggc ttgcagttta gaggcgggat cgcagaaagc acacgtcggt
    15601 accctggctg agtcatatcg aataggacaa ccgccggttc cacgccttcc tctccccaat
    15661 cttcctcctc cagtaaatcg gcatccatct gtccccatac cgccaatgta tcgggtcctg
    15721 tccagcacac tggcccatcc caatctatgg tttgccaaag atggcgaact gacggaccat
    15781 tttccgattc ccatgggttc agcagccaat cagataatga ccaagttcga accactccta
    15841 atggagccca tacccatcct gtatccgcca tccattttcc ctctggagaa gccagcagtc
    15901 tcccatgaaa gtaatctaga taatgctcat ctttgctttc gttgttataa acagggctag
    15961 gtcttgctgt caaaagcctg cctgtttcta tatccgtcag atccagccgg ttccattccg
    16021 ttccatgaac aaggatacac ataccgtctt gatgtacaaa tgccaggggg aacatacttt
    16081 tatcatagtg gtattcgtcc cgagataatt gcattttttc ttgagcatag actaaatcat
    16141 acactgccgc atgccggcca aaacgattgg atatggctac gtacttgccg tcaggactgg
    16201 tcaccatttg gacaggttgc atgggattaa aatcaggaat acaaatacat atgcataatt
    16261 ctgcactacc agagcgaagt tctagtctcc acagttctgc ttgtgtgttt agtgctagca
    16321 gggttatgct gccctgagag ccacctttta caggatgaat ggccgtaagg cgtccgatag
    16381 acgatggtaa atcaggtaaa gaaacgtgag agaacggcat tatttaaccc cttttactct
    16441 ggataaatca taaggtatac ccgcatttgc gaagatagta ttatcgacaa aaaatccgag
    16501 ttcaagcaat gcagtcaata ctttcataaa aactcccggt tttttcttgc agaataattt
    16561 aaaatatgta atttcgctag gattactttt gagaacaaaa taggagtaat tcatcaagat
    16621 caaatgggag atgaactgct ctgttggaga ttgatgctca ttgatacagt cgatcagcac
    16681 ctctaatgcc ctatttttat tagagttata ggcttgtata aatatctttg cttctgcaaa
    16741 cgacttgttg aaatcatcat acggaaaatc atatacatca tgactgccca agatgaagtt
    16801 gaccaactgg ccttgcaaat tttttatttt tctcagcgtt gctcgggtat ccatatccat
    16861 cttatttttg ttaatatgct catgcaaaat atcaattaga atgtgcaaat catactgctg
    16921 tccgtcttcc atgctgtaca gtaacttatt attctcaatc gttagacgat cataaatgtc
    16981 atcacctaaa cccagttcaa ataaaagctg gtgaaggaaa aatagcctgt cctgagcaaa
    17041 cgtgaattca ttgcctcttt ctgctaggtg tgaaacctga tactgataat agaaacaaca
    17101 taagtttttt cggctataag caacatcttt atgtatatca aacatgttaa aaataagcgc
    17161 aagcaatcga atcagacgtt cagcatccgt tacgcttaga atgggatgat ccattttggt
    17221 aaatagcgac ctgtcaaata aatcatgcca tcgcactaaa gaaatatgat cctgctcatt
    17281 tatattcaga gttaatattc ttaaattttg ctcttgatca ggataggaat aaaatagatc
    17341 ttcatgattc aaatcagaaa tacgctcatt aaaataggct tttaatttgt aatcgtatat
    17401 tttagaaaat gacatttctc tcctccttgc accttatttt cgaactccta tattgtaaaa
    17461 ttaatcagga tcaactggca aggcggcata aatacagaaa catatgttct tcttttctat
    17521 attatgatat ctttatacta gaaatgaaac gttatgtcag agaccatagc ctacgattag
    17581 aaaggaatac acacctatga aacagttaaa tgaagcgctt acccggtttg tacaccagca
    17641 aaacttgtat aatgaagcct acgggctgtt ccaagaccac gatatccagc cccgttcaga
    17701 gagtataaca gattgctggg acagtcggat tcctctatct cctgagcttg cgtacatgta
    17761 tagccactat gaaatgatcg atgccaaggc agcgggaaca cacaaattaa aaaacgcggc
    17821 agttgaagtt ggggatgccg cagttctctt ttttgtcgca ccagaacatt tatatcgcca
    17881 acagctaggc tatcgcttca ttacgtctgg tgagcttgtc caagagtctt cttcttggcc
    17941 ctaccatcat gttgtaattg ccacgtttaa tgacgatcca ctcattgtcg atactagcgc
    18001 acccgattct cctgtatatg ctgcaattga aggtggcgca gcgcagcaga ttgctgactc
    18061 tctagctaac ttctttactg ctctttccat cctgatcgaa ggtgcctgta cctttaaggg
    18121 agaattggta gatgaagata catacgaaac caaagcagca tatatcgagc acgtaaaacc
    18181 attgctgcat cacttactgg gcgagaacca aaccacgtat ttgctgaaat acctatcctt
    18241 ctgttagaaa tcctatttgt taaagagagg tggggctttt tatgatctat atcgcattac
    18301 tgcggggcat caatgtcggc ggcaacaaca agattgagat gaagaagctc aagcaaacgt
    18361 ttgaacatgc aggtatgggg catgtgacga cttacatcaa ttctggaaat atcatatttt
    18421 ccagtcagga gcggtccaac caggagctat cgctcgtatt ggaacaggcg attctggagg
    18481 attttagctt acccatccgt gtcatcgtcc gtaatatgaa ggagattcag agcattatgg
    18541 aggcactacc gaatgaatgg gctaatgata cacagatgaa aagtgatgta atgtttctgt
    18601 gggatgaaat taacgatatt accgttctgg acaagcttcc tttgaaaccg ggaatcgggc
    18661 atgtcatata tacgcccggg gccgtactgt tttctgtcag caaggaacaa gtcaccaaaa
    18721 gcgggttaac gaaattagtc ggcaccaagc tgtatcagca aatgacggtg cggaatgtga
    18781 acacaacccg gcagatttat aagctgatgc aaatggctga acaggaagag ttacgaaata
    18841 cgagctcttg acggtagtcg tgattaaata gggataggca agataaaaaa catatagtga
    18901 taatacagcc aacatcttat tacaaaggtg ctggctgtat aaataaaaaa actcatcaaa
    18961 aatattgttc gatgaaatta tcaatcttag ttagatcatc ctttatcatt tgttcaactg
    19021 aagaagtgtt aagcaatgga gctaactttt ctgggtgtgc tatgcaatat tcataatcaa
    19081 ttgcacattc tgtctcgtac ttatttgtgg cgatcttttg gaataaatca taagacaaat
    19141 cagaagtcac ttcattaaac tctacttcca acatttctaa aaacctaagt aaagtccaat
    19201 ttttaattgt actcgttact tcttggttat cgttcatctc ttgaagtgtg tagatggaag
    19261 ataaaccaaa tgtcaatagt tctgtaccat tcagttcctt catgtgatca gtaaatgatt
    19321 gaatgctttc caaaaaaaaa tttttacttt catccgcaaa aaactcaaca agaatacaaa
    19381 atacgttata aatataagta tgaaattcgg actcgtttat aatccagtca atcaagctca
    19441 aaattttgac tttattatat gaatgatcat taatattctt acataataga tagacctgaa
    19501 tctcagaggc tataaaatac aaccatccat tattatgccc caagtagctg ctctctttga
    19561 tcaagttcca gtcttcattt gatatattga gccaatgttt caaattatcc cgattaaagt
    19621 acatttcatt atgttcctgc gctgcaactg caatcttggt aagaatttca tattcagaac
    19681 aatcaattga actaaacatg ttgtcaaaga aattgcgaat ctgattctct attctattac
    19741 ctcgtttata ttcatcaaca attttcgcga gaaaaagcgg atcattagaa taatatgttc
    19801 ctttccattt agattttccc atgaacaaat cttcttgaac tcgatccatg atagtaattt
    19861 cagagcctac tattccagct aaattaatta aagaatccca actatcttga tcatcccaat
    19921 gtatataggg aagcaactcc tccataaaat ccctttcact tgtttcttcc acaaagatat
    19981 catctctatg aaattcgact ttatttttat taggattatg atttgtaatt ttttcaaagt
    20041 tagaatgaat tctattccac tttactgaat atccgtccca atttagagtt ttctccaata
    20101 ttctcatggc cttaagggat tcttttttaa cctgtacgtt atataattcg atcgcttcag
    20161 gagcgtctcc gaataacaaa ttctcgatct caatttccaa atcatcggat gcataaaagt
    20221 cataatcatc cccaataagc caaataattt tatcagaaat ttcattgtag ttttcttgaa
    20281 gatagcagtc aaagtcttga ccatatatat ctctgaattc ataaaagacg atgtaaaatt
    20341 tcaaaaaatt aattttagaa cgatagccat ctaataactc tttcatagca ggaatttcga
    20401 acccttgctt taataactta ttgacaatct taggaacacc atatttctct tcatcagaaa
    20461 gtgcataacg gtcatctttt aacaaactat taataaaaaa aacctttaat ttttctatta
    20521 catcccttaa tttttgagag ttatattgct cattcaaatc taatatttgt cttaatttaa
    20581 gattgtaact gtcagtataa tctgaagaga aataaaagtc tgtaaatcta tcatcatctg
    20641 tacagtattc ctctagtcca ttggagtaga taaaatctaa acgttcgtaa tctttagcga
    20701 ttctatcaat aattcctgga ataattgtct gctcaaactc catattatta tgttcatcaa
    20761 ttaaatttag taaaagtaaa ttgtgagcga aaaacaaaat aggattcatt aaattaatac
    20821 tcttaataag atttagccca tacagtgaca aattttttga tattaaatgc ctccaaaatt
    20881 ccatcatgct atgattgtta aatcctacaa ttgttttttt tacttcaaag tcagtcaata
    20941 cctgtcaatg ttctgataaa attcatatct ctaacgaaac aaaaagaggc ggacaattga
    21001 cccaaagcct catcaaaact ttgccactct tgccaaggaa gactttcttg taagtcccca
    21061 tagcattttc ttaaaatatt taattcaacc ggatatccaa agatcgccat acatattcca
    21121 agataaactg cactttttga agtctcatga aggtgattat acattctctc ataaatttca
    21181 ttgggattct tcaatgtttc caacagtatt tttcccggat acataccatc atgttttatt
    21241 ttagaaagaa gatggatcgc atcattaata aatcggggat tataattatc gtgattaata
    21301 attttgtcag aaactattac aatgctgtgc aaaagactat actgcaagtt tgactttttt
    21361 agaatactcc aacatatcct catcttgtct gagttttcta agctagttga agataactca
    21421 acactcatat tttgaattat tacctttaac tcttgtaata atttcatacc ttcaaaaaga
    21481 atattttttc tcgaaatcaa tacaatttta tgattatttc cactaataat gctcttaagc
    21541 attcgataaa ttttagattc accatttttg atctgattat tgacgtaatt tacacctaaa
    21601 aagtcatcta ctacaaataa ttgcttttta tctgagcgat aaaatttata cacatcttca
    21661 atggtatctg taaaaaaaag atcaagctcc tcattttgca tcaaataatg gaacgctata
    21721 ttaaaaccta gcaccgtttt cccaattccc ggttcaccat ataccaataa acaattatgt
    21781 gaatccataa tatcaagtga ttcatgataa gctttcgttt ttatgtagta ctcaacgtta
    21841 tttttcattt catttaagtg aaattgatta aaattattag gtccacgcaa aataatattt
    21901 tctaaaatat gttcaaaaac tactgtacta ggcgtccata aattattgta ttttatttga
    21961 ataaaagaaa acttagggtc agtaagatac tcatttagtt ctattctacc aattatatct
    22021 ttatcagaat gaatatagcc tttaaataaa tccattattt ccctttgttg ttctttattc
    22081 aatccaactg atgttactaa aatatatcga ctcggcttca aattacgcaa ctttaatact
    22141 tcttttttca aatttccttt caaaatgtta aaatcatttt tatagcattt tgcttgaata
    22201 atagtattat cactgtacct atatccatca atgcctccat ccctaccttt aggatatctg
    22261 cgaaatacat tgggttctaa attttctcga actcgaacaa tatctattgc caacgcctca
    22321 aattcaacgt catctaataa tgcgtgaaaa tcataattgt ttttcataat ctcccatctt
    22381 tctaagac
//
