LOCUS       NZ_CP085682            20549 bp    DNA     circular CON 22-AUG-2024
DEFINITION  Paenibacillus polymyxa strain YS18-2 chromosome, complete genome.
ACCESSION   NZ_CP085682
VERSION     NZ_CP085682.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5840603)
  AUTHORS   Liu,J. and Huang,Y.
  TITLE     Complete Genome Sequencing of Paenibacillus polymyxa strain YS18-2
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5840603)
  AUTHORS   Liu,J. and Huang,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-OCT-2021) Department of Sericulture, South China
            Agriculture University, Wushan, Guangzhou, Guangdong 510642, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. v.3.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 253.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024584565.1-RS_2024_08_22
            Annotation Date                   :: 08/22/2024 06:09:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,167
            CDSs (total)                      :: 5,043
            Genes (coding)                    :: 4,970
            CDSs (with protein)               :: 4,970
            Genes (RNA)                       :: 124
            rRNAs                             :: 13, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 13, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 40 of 73
            Pseudo Genes (incomplete)         :: 41 of 73
            Pseudo Genes (internal stop)      :: 12 of 73
            Pseudo Genes (multiple problems)  :: 18 of 73
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:38:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3076473
            Orig. end                         :: 3097022
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP085682.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20549
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="13"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     cand_cluster    1..20549
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20549
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10549](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10549)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     misc_feature    911..925
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(1005..1019)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.88"
                     /tool="antismash"
     misc_feature    complement(1079..1094)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.04"
                     /tool="antismash"
     misc_feature    2311..2326
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.48"
                     /tool="antismash"
     misc_feature    2837..2850
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.31"
                     /tool="antismash"
     misc_feature    3057..3071
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.3"
                     /tool="antismash"
     gene            complement(3193..4365)
                     /locus_tag="LJR53_RS13165"
     CDS             complement(3193..4365)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371417.1"
                     /locus_tag="LJR53_RS13165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M20 family metallopeptidase"
                     /protein_id="WP_257125910.1"
                     /transl_table=11
                     /translation="MLEKWVQELKDGEQELIAWRRYLHQHPELSFEETNTSAFIADQLR
                     SFGIEVRTNVGGNGVLGFLEGGQPGRTIAFRADFDALPIQDEKDAPYKSTVPGVMHACG
                     HDGHTAALLGVARVLSHHRETLKGKLVFIFQHAEEKPPGVAKFMIEDGCLDGVEAVYGI
                     HLSSEIPLGKIGLKSGPAMAAADAFSIQINGKGGHGARPHQTVDSIVIGSQIVNGLQQV
                     VSRRVDPTESAVLTIGVFQAGTAFNVIADKAKIEGTVRTFNKDIRKEVENEIRSIVKGL
                     TDAYHAGYEIDYLNGYPALVNAEAETERVRELVSRLYGADAFMDLKPAMGAEDFAYYLE
                     QRPGAFIIVGARNEDERTHFAHHHPRFDFDERALLISGHIFLALALEYLQ"
     gene            complement(4594..5103)
                     /locus_tag="LJR53_RS13170"
     CDS             complement(4594..5103)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427739.1"
                     /locus_tag="LJR53_RS13170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_017427739.1"
                     /transl_table=11
                     /translation="MGYNIKSELKLSIKSVPESQKDIIVQLMQFYLYDFTAYLRIDVTE
                     KGTFPAYPDLYQYWTSGEQKLPFLIWRQDIPVGFALVDRMSSNREADYYMAEFFVLRPY
                     RHNGVGTWAAHELFGRFNGRWKVTQMSTNRPAQSFWRKVIGSYTNGEYREQTHPVRGNI
                     SQFFNT"
     misc_feature    5087..5103
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.71"
                     /tool="antismash"
     gene            5213..6313
                     /gene="xerS"
                     /locus_tag="LJR53_RS13175"
     CDS             5213..6313
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene="xerS"
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019687399.1"
                     /locus_tag="LJR53_RS13175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosine recombinase XerS"
                     /protein_id="WP_017427738.1"
                     /transl_table=11
                     /translation="MNIQKIIDRRKLDEKLPDLPWYVQQFMDYKLPDLSPSTLLEYVRD
                     YEAFFSWLRSEGLSAGETNAQVTLEELETLHMDSITGFRLFLSTKREGSNSRITISRKL
                     SSLRSLFHYLSQIAEDENFYPLLKRNIMAKVEIKRVHKPKDTAAKLKGKILEEEELLEF
                     IGYIYEGYGQDLADNKQALYSYELNKERDACIASLILNSGLRVSEIVNLNMDDLDINNK
                     LLYVYRKGNNDETFKTPVYFREQSKDDLALYLSLRHTRYRAPKKEKALFVARPNGSAEG
                     KRMTKRAIQAMIIKYAKRFGKPYLTVHKLRHSFATDYYLQNDIYKTKEQLGHASTETTE
                     VYAHLTDKTMSQAIERRIETQTDSAN"
     gene            complement(6322..6873)
                     /gene="mobB"
                     /locus_tag="LJR53_RS13180"
     CDS             complement(6322..6873)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="mobB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371420.1"
                     /locus_tag="LJR53_RS13180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="WP_016820736.1"
                     /transl_table=11
                     /translation="MKTKYPFVCQIVGFKNTGKTTFLGGLIRYAQQSGLRVAVIKHDGH
                     EFEMDHEGTDTYKHRQAGAEGVAIVSAGRTAILEEHSRPVIGLIRHFQAYDCVLLEGFK
                     QEKYPKLIMVREQSDAQLVQELTNVQGVVVWEYHMDWAQDYYSDEQTVQIFPADASEPA
                     GCWLLEQIQRHKMGFQTEQG"
     gene            complement(6870..8147)
                     /gene="glp"
                     /locus_tag="LJR53_RS13185"
     CDS             complement(6870..8147)
                     /GO_component="GO:1990586 - divisome complex [Evidence
                     IEA]"
                     /GO_function="GO:0061599 - molybdopterin molybdotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="glp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371421.1"
                     /locus_tag="LJR53_RS13185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gephyrin-like molybdotransferase Glp"
                     /protein_id="WP_025365007.1"
                     /transl_table=11
                     /translation="MNQTPLNTEKFQRKAVKVEEAQSRIASYVQQGEREDVGLEQAHGR
                     YLAMDLTAPHPYPRFRRSGMDGYAILASDTEVCSTGQEIWLHVIDEIPCGTVSDKRVET
                     GMAVRIMTGAQLPEGADTVVMLEATQLREENGQTYVGLKKRMEVGKNVTQIGHEIKEGQ
                     LLLSKGTCVGAGHVSVLATFGVHRVPVYKKPRVAVFSTGSELLAVDEPLQPGKIRNSNT
                     YMLASQIREAGGEPFILQAIHDDLNLARASVREAIAAYDIVVTSGGVSVGDFDIMGDLV
                     RQEDVNMLFNKVTMRPGSVTTAAVIDGKLLFALSGNPGACFVGCELFVRPTIQMMLSSA
                     HPYLQTWTAKLGADYTKVNNYTRFVRSSLEIRSGQVYAIPARVDESSAMVTIKDSDCLI
                     VVPPTTEGLHEGEEVHVLVLQGGQVT"
     gene            complement(8343..8645)
                     /locus_tag="LJR53_RS13190"
     CDS             complement(8343..8645)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LJR53_RS13190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_257125911.1"
                     /transl_table=11
                     /translation="MFRSEYTGKLLFYQLYCGVDWMVADKNENVTCTSFYTIKMARLAS
                     GYSELIACNILGMSMNELKHIEEDSSDLTIARAQQMSSLYEVSIDSIYFGKNNLT"
     gene            8671..8886
                     /locus_tag="LJR53_RS13195"
     CDS             8671..8886
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024835.5"
                     /locus_tag="LJR53_RS13195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_016820733.1"
                     /transl_table=11
                     /translation="MQKLTRGKCLLKEELKSHGRTQSWLARRTGYSRQQISNWIAGRDK
                     MSFEAAVLISRILECKAEDLYEWELA"
     gene            complement(9157..9891)
                     /locus_tag="LJR53_RS13200"
     CDS             complement(9157..9891)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820732.1"
                     /locus_tag="LJR53_RS13200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_257125912.1"
                     /transl_table=11
                     /translation="MEEGKRILATPLLDDNSLGDCSFFCENHLVAIELWKPKSNYHIPL
                     FHTSHGRFTVPTTLHECSVGLPTFCNLDGSNLVNITQVDKIVTGDYGGGQVVFKNQNIK
                     ESINSANLSRWKQIYENAMNADREIRYIFGSEIKVVGKAAVSGFFKVGNMLSVDMWEPK
                     KNYYVPRFHSGDRSYSIGLTAQACREAFPYLYPAYKDTLINLELVCEIESNAFGGLVRF
                     KGSDFTCSMSHNKLKALKKLWK"
     gene            complement(9897..10028)
                     /locus_tag="LJR53_RS13205"
     CDS             complement(9897..10028)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427735.1"
                     /locus_tag="LJR53_RS13205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_016820731.1"
                     /transl_table=11
                     /translation="MDKKLARALSISLGNYANESTKKEKTIFGAKPVPAELKKTEKN"
     gene            complement(10001..10549)
                     /locus_tag="LJR53_RS25950"
     CDS             complement(10001..10549)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016526.5"
                     /locus_tag="LJR53_RS25950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="accessory gene regulator ArgB-like protein"
                     /protein_id="WP_371317230.1"
                     /sec_met_domain="AgrB (E-value: 1.4e-20, bitscore: 71.6,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLETLSRHIASEIKKADPDGPTSVEVMEYAIGVKMTEISAVLMVA
                     VMAWITGHFWGALLALATIMFVRRFSGGVHFSNLTLCVCFTTAICVTIPFVSLSLSTIL
                     IINACSLLMFVVYAPNHFIYINKTKHHKYYKTICILVCILNFFIQSHIICLSLIIQAFS
                     ILPLWKGGERKWIRNWREL"
     gene            complement(10500..11213)
                     /locus_tag="LJR53_RS13210"
     CDS             complement(10500..11213)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820730.1"
                     /locus_tag="LJR53_RS13210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_016820730.1"
                     /transl_table=11
                     /translation="MLSAFLYIILGFFDALAAVTLVLKLYMLPVWENRRKIIFYAMGIA
                     LFSFLMREVIGMPKFDFPLQYLLMVLFLRFGLGIKTYLAAFSAGSGLTAYINLQLFVYI
                     FANFFGVAQPGVISDTAGSSIYVIQLASIFTAYFISFVMGKYNFGFSFIIQPPHDFLKG
                     ENYLSPLNKMFIIGSLISFVTILVTLYMLYNSNTIGLLSISLLTFGISYFLSEKGDYED
                     ARNAIEAHRIRNKES"
     misc_feature    11334..11348
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.08"
                     /tool="antismash"
     gene            11480..11713
                     /locus_tag="LJR53_RS13215"
     CDS             11480..11713
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820729.1"
                     /locus_tag="LJR53_RS13215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_016820729.1"
                     /transl_table=11
                     /translation="MALSDNFKKLRIKYHLTQQELAEIAGVTNKAISAWESGLSEPRMG
                     AIEKIARHLHIKKSNIIEEDGIEHISPDRRSK"
     gene            complement(11846..12601)
                     /locus_tag="LJR53_RS13220"
     CDS             complement(11846..12601)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310483.1"
                     /locus_tag="LJR53_RS13220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4247 domain-containing protein"
                     /protein_id="WP_019687402.1"
                     /transl_table=11
                     /translation="MGKRTWQYALKVIVALSLFVSVLSGCGAPNVKDTYPLESVSGSGN
                     STSYVYRAAGKTVPEVAEELKEQRTPEQISPQSNERMFLVYSDEWYHLQQDPAKKEDTL
                     IEIDSKKYVEQNYSSSFLKGYLTATVLDALFDSLRGSGSYRGYSSRDVYRPSQGQYRAP
                     TAQEKKAIPPITVERKGSVTRRGKNSDSSVGSSGSLFDRGSSSSPSRGSISRDRGSSGG
                     SSIFDSPRKSYSKPKTRSGSGKISRRSRR"
     gene            complement(12615..13121)
                     /locus_tag="LJR53_RS13225"
     CDS             complement(12615..13121)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010348250.1"
                     /locus_tag="LJR53_RS13225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4178 domain-containing protein"
                     /protein_id="WP_017427734.1"
                     /transl_table=11
                     /translation="MSVWKRISNLFAKPEPPKAEKSMLHLNPGDICEVSLVTYEVVGRV
                     HNRARNAVVLTLQDGNQVSYLHIEERETLQFGLYQAIDGRLDNPEEVPTILELDDTTYH
                     LEEQYFGHVTVMGRAPFRQGGEQHVWQYQSDDYHLLRVEWQDGRFMLYEGEEVITGDVK
                     VIRAS"
     misc_feature    13098..13112
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: strong, score: 24.68"
                     /tool="antismash"
     gene            complement(13146..13553)
                     /locus_tag="LJR53_RS13230"
     CDS             complement(13146..13553)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820726.1"
                     /locus_tag="LJR53_RS13230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF350 domain-containing protein"
                     /protein_id="WP_013371429.1"
                     /transl_table=11
                     /translation="MHFLETMKAMLVWTGAGAILLFVLMYVDSLFTKYKDFAEVKAGNM
                     AVTVRMIMKLIAQGYILSGSIATANNLLEALVYSVIAFIILLVLEVIVRLLLRYWAQFD
                     LDKGTQEGKIGFGLFSGALHLVGALIITACF"
     gene            complement(13683..14351)
                     /locus_tag="LJR53_RS13235"
     CDS             complement(13683..14351)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007432515.1"
                     /locus_tag="LJR53_RS13235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PspA/IM30 family protein"
                     /protein_id="WP_013371430.1"
                     /transl_table=11
                     /translation="MSIFKRLRDLTMSNINAIIDKAEDPVKMTDQYIRDMQEDLEDAEK
                     AVAAQIAIEKRFKQQYEEQAALVKKREEQAHTAAKAQNVDLARRALEEKKSAEQKMNEF
                     QAGYEQNKAAADNLRGKLDEMRRQLTEMKNKRETLVARYNAAKAQTEINKAMNGFSSDT
                     ATAGLKRMEEKMLQAEARAEASNEMASKEKSLDEEFKELDKKSAVDDELAALLKQYENK
                     "
     gene            complement(14438..15460)
                     /locus_tag="LJR53_RS13240"
     CDS             complement(14438..15460)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371431.1"
                     /locus_tag="LJR53_RS13240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADH:flavin oxidoreductase/NADH oxidase"
                     /protein_id="WP_257125913.1"
                     /transl_table=11
                     /translation="MTDLFTPYQLKGLSLRNRIVMPPMCQYSVEAKDGKPTDWHYVHYV
                     SRAVGGTGLIIVEMTAVHPDGRITDRDLGIWSDEHIPAYRKMVEEVHKYGAKIAIQLGH
                     AGRKAEDAEPPVGPSSIPFSERFKEPHALTRAEVKELVLAYKEGARRAVEAGFDTVEIH
                     GAHGYLIHQFHSPLTNTREDEYGQDLSLFGVEVIRAVKEVLPADMPVLMRISAKEYVQD
                     GYDVEYIAAIGERYRDAGVDIFHISSGGEGPIGSSGGPSARAGYQVDLAHTIREKLNVP
                     VIAVGLLDDYEDARRVVQHNEADLVAVGRAMLRDPYWALHASRALKVQADIPEPYLRGF
                     "
     gene            15764..16570
                     /locus_tag="LJR53_RS13245"
     CDS             15764..16570
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820724.1"
                     /locus_tag="LJR53_RS13245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_257125914.1"
                     /transl_table=11
                     /translation="MRYRGVLPCLALLLAFSSFPVHADTPPNIGTPHRKEATVATSVYQ
                     SKDRATPTLAMLRKKHADIFKMCGPHTRQIALTFDDVPDSRYTPQVLDVLHANGIKATF
                     FIVGHRAEKHPGIIRRIIREGHAIGNHSYTHPDFRKATPERFRHQITKTERILEASAGF
                     RPRLIRPPYGEITEPQIQWARRHGYMIVNWNVDSLDWKGLSKTQIQRNVIPATRPGSII
                     LMHAGGGQSSNLQGTVQALPGLIHSLKAKGYKFVTVPRLLHTSERK"
     gene            complement(16770..17438)
                     /locus_tag="LJR53_RS13250"
     CDS             complement(16770..17438)
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019687404.1"
                     /locus_tag="LJR53_RS13250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3D domain-containing protein"
                     /protein_id="WP_019687404.1"
                     /transl_table=11
                     /translation="MKHLKHIGKTMKFAVLAAAIAGLAQTAGVANAASLHTAKEGDTFF
                     LLAQRYGVSVDDLTKANPDIASNNIYAGLQIKVPDEKSVKAASDSKPQLLTEKAPANER
                     PTIEAWGKTFNYSKVVDVKATAYSAAADENGKWGAVDYYGNPLKLGTIAVDPKVIPMGT
                     KVLVTGYSHPGLPDHSFVAVARDQGSAITGKRIDIFIPGNKSFVNDFGFQNVKLYVIDK
                     "
     regulatory      complement(17445..17614)
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    17655..17673
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.99"
                     /tool="antismash"
     gene            complement(17859..19204)
                     /locus_tag="LJR53_RS13255"
     CDS             complement(join(17859..18817,18817..19204))
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611934.1"
                     /locus_tag="LJR53_RS13255"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS3 family transposase"
                     /protein_id="WP_257125915.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MSNKRGASKIFSEQEIKQLEANPNVQKVTDKTITYAPEFKVEAVK
                     AYEAGQTPMDIFLRAGFDIDTIGHEKPKKSLYRWRNIYAAHGEASLLEEQRGKGSVGRP
                     QTNNLSTEEKLKRAEARIKLLEAENGLPKKARSARKAEDAEETLTPSERYQIINLTIRQ
                     HSLKRMTRYLCELSHISASGYYRWLHAEERRQLQARADEHDLALIKMHFYALHGKAGAL
                     VIKMRLERENGVTMNHKKIRRIMRTYKLVATIRQANPYRKMAKATQEHQTCPNLLKRQF
                     DQGEPEKVLLTDITYLHYGHGQCAYLSCVKDGATKQILAHYLSSSLELVLVERTLQLLI
                     ERFDGNVHPEAILHSDQGMHYTHPKIRLLVRKAGFRQSMSRKGNCWDNASMETFFGHMK
                     DDLEYKSCATIQELRACIDNYIAYYNSGRYQWALKKMTPDEFRSHLLAA"
     gene            complement(19349..20071)
                     /locus_tag="LJR53_RS13260"
     CDS             complement(19349..20071)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371435.1"
                     /locus_tag="LJR53_RS13260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_257125916.1"
                     /transl_table=11
                     /translation="MITVKQLRKSFGKNEILKGIDIDIAKGEVVVIIGPSGSGKSTFLR
                     CMNLLEQPTEGEILFEGEPITARGHNINATREKMGMVFQHFNLFPHKTTLQNLTLAPTQ
                     VKKQSGKEAEKIALELLRTVGLEDKKNTYPNQLSGGQKQRIAIARALAMQPHVMLFDEP
                     TSALDPEMVGEVLDVMKKLAEGGMTMVIVTHEMGFAREVGDRIIFMDNGQIIEQGTPEQ
                     VFGTPSHDRTRDFLAKVL"
ORIGIN
        1 tgctagggaa acgggtgagc ttcctgtatt ggttatttta aacttggaac tgatcgtatt
       61 acttgttgca gatacattcc cattgaagga ttgcaccttc agagcaccct cgcctgttcc
      121 cggctcactt ggcgtatccc ctttcaccgt aatcgtgaac aacgcatcat tgcctgtact
      181 aaaatggaag ttgagcgttg tctctccttt aggaagttta gataaatact tgttggtaag
      241 aataactgtt tcttcactaa ccgtataatc ttcacctttg ttcagtgcca cactcccctg
      301 cttgatcgct tctagtgtat taccgttaag agtaagcttg acagtaatat cggtattact
      361 gttagccact tcataggttg cagccgtcgg cgtaatactt gcttgcccgg tagatggctg
      421 gtcaccaccc acacgatctg ccaccagaat gccgcggcca ttcgttccga gataagcacg
      481 tccgtaaacc cgaggatccc caataatggt ggtcacacga gcatattgat gcttatcatc
      541 attaatgcgt acccagtttg tgccagcatc gtccgagcga taaaatccac gtgtaccgtc
      601 aattttacca acgataaaca ctgctgcatt ggtgcgattg ggtgctgctt tgccaaagcc
      661 tacaaaatcc gcctcctgca catgagcaag cttggtgaat gtaacacctg aatccttgga
      721 atgccataag ccgtatggcc ctccgtcctc ggagcctcca gcaaaccaca catctccttc
      781 cgctcctcgt acagcaccaa aatctgcatt acctacactt ggcaaaccag taactgtgga
      841 tggtgtgaag gatgcgcctc catcaacact tacatatatt ttcccagcag caaacgcgta
      901 gtatttgtta ggatttactc ggtcagaggc gatctttgca ttagctggaa ctcccgtgct
      961 tgctgtccat gagtttcctc cggttttgga ataaaataca cctttgtccg atgtactcca
     1021 cagcaatcca ttaccatttg ccgctacagc gatgctgcct cctcctgctg taccggaagg
     1081 ctcgctatta gctttgtacc agttcgctcc gccatcattg gataatccga tagatttggc
     1141 gtttggatct tttttatagt ccgctttacc tacccgagcc ataaaagaag ggttcaactc
     1201 ggcataatca atgctttcgc tgcttgtaaa ggttggatta tccagcattt tagcaggagc
     1261 cttgaacaga tcgtcatgtc tgaatccgga gacatcaccc actgcactca ccagaggagc
     1321 tccagttgga gggctcacca aatccaaaat cgccgtttct tctacccctt tagcggctac
     1381 cgaaatgtcc agcttacctc ccttgtccca attggtcaga tttttagagc cataaatcgt
     1441 agctcctgtg ccgtacagca tatgatctga attaaatgga tctatttcca gatctccaat
     1501 catccagccc agcttgggcg atacttccgg cggtgcagga ttggcattga aagtcagcca
     1561 aggcgcaccg gatatatcca gattgtactt cagcttacga gctggataac catcaaattc
     1621 ccaaataggg ctccaagttg ccccacgatc agtactgcgg taaatcgttt catccggcca
     1681 ccaggcattc aacgttgcaa ccataagtgt acctggcttc tgggcgtcca ctgtcagtcc
     1741 accatatcca aaatgattgt ctgcgttgct gctggcaacg gggctaatgt tagtccactg
     1801 tccactggct gtattcagtt tccacagctc accctttgtt ccatcatacg gtccagctcc
     1861 atcgctgtaa gaaatataca ggtcgccatc tggcgataaa acgccgtgat gtggcaaata
     1921 gcctgtaggc tggcccgcta tagcagacca ggttgtcccg ccatcagtac tgcgatagac
     1981 actttgcttt ttatctgcga cacccacata gatggtctgt gttgctttac tggaagagcc
     2041 cgtttttttg tcaaaagtga tccaggctaa accgacaata tcactggtgt attcattgga
     2101 agggtcctgt acatacgtcc ccggattcgg aaaactactc accttgctcc aggtcgcccc
     2161 gtaatcggag cttttccaca atccattacc acttcgagct ccgaagaata atatattgtt
     2221 tttattcgga tcaattgtca gacgttcacc catcgagcgt cccggcatat tgcctcctac
     2281 cttgaagggg agctttgtca tctgccacgt attccccttg tcggtagagc gcataatttg
     2341 cccgttttgt ttatcccagg aattagtata cgtgcctgta gctatatata cacgattcgg
     2401 atccacaggg tcggtggcta gtgcatcgac accatttttg ttccaatcct cccagcccac
     2461 agaatccgtc agcggaatcc agctttcact cgcaggattc cagcggtaag ctcctccaat
     2521 atctgtacgg gcatagatca gatctttttc cgtttcatta aaaataatac caggtacaaa
     2581 accacctcca ccgcctgtaa cgacactttt ccaagtataa tcgtcacttg gagcagcatg
     2641 ggtgggtgct atcatgcctg tccaggaagc acccgctact ataagcgcca aacatacaat
     2701 tctcaacctg ctttttgcct tagtcaatga attcaacctc cttctccgta atcatttaaa
     2761 aatgcaagtc atttcgagct aaaagtaagc agtcaattgc ggattcgttc ctatcgttat
     2821 tattccattc atcaatcaaa caagcgttct ctcaagctca cctccagtaa tccaatagat
     2881 ttgcagtctt ttttgttagc gcttacatcg gtgtctgctc aaaagattcg tcatcttttt
     2941 ctcatttcct tgtgtgaaaa atcaagataa tgtaatagta tcttctgctt gataacttgt
     3001 aataaaagag ttggcttcca cttacagttg atacctctta taaattacta atatgaattt
     3061 ttcatataat gaattatttt ctttaaattt cattcgaacg aggtaccaaa atactttgat
     3121 ttacagcaaa aaaccgcgct atgcgcggtt cgggcttccg taatgctatg gctattcatt
     3181 aataggttga aattactgca aatattcaag cgccagcgct aaaaaaatat gtcctgagat
     3241 gagtaacgca cgctcatcaa aatcaaagcg aggatggtgg tgagcaaaat gggttcgttc
     3301 atcctcatta cgagcgccca caataataaa agctccaggt cgttgttcta gataataggc
     3361 aaaatcctct gctcccatgg ccggttttaa gtccataaaa gcatctgctc catacagcct
     3421 actgactagc tcacgtaccc gttctgtttc ggcctcggca ttcaccagag caggataacc
     3481 attcaaataa tcaatttcgt atcccgcatg ataagcatcc gttagacctt ttacgatact
     3541 acgaatttcg ttttcgactt ccttgcgtat atccttatta aacgtacgta cggtcccttc
     3601 aattttggct ttatctgcaa ttacattaaa ggcagttcct gcttgaaata ccccaatcgt
     3661 taacactgct gattccgtag ggtccactct gcgactcacg acctgttgta gtccgttcac
     3721 aatttgactt ccaataacaa tggaatccac tgtctgatgc ggtctggcgc catgtccgcc
     3781 cttgccgttg atttgaattg aaaaggcatc ggcagcagcc attgccggcc cactctttaa
     3841 accgattttg cccagtggaa tttccgagga aaggtgaata ccatatactg cttccacccc
     3901 atccagacaa ccatcctcaa tcatgaattt ggctacacca ggcggttttt cttcggcatg
     3961 ttgaaaaata aacacaagct tccccttcag tgtctcacgg tgatggctta acactcgtgc
     4021 cactcctagc aacgcagcgg tatgaccatc atgtccacaa gcatgcataa caccgggaac
     4081 ggtcgattta taaggcgcat ccttttcatc ctgaatagga agtgcatcaa aatcagcacg
     4141 aaatgcaatc gttctacctg gctgcccgcc ttctaaaaaa ccgagcacac cgtttccacc
     4201 gacattcgtt cttacttcaa taccaaaaga gcgtaattgg tctgcgataa atgcagatgt
     4261 attcgtttcc tcaaaagaaa gctctggatg ctgatgcaaa tatcttctcc acgcaatcag
     4321 ttcttgttca ccatctttta gttcctgaac ccatttctcc agcatattac cctcttttcc
     4381 tattgaattt atatacttct atccttatct taccataaat gattccaata agttatatat
     4441 gaattaccaa ataactgtat acctgcgttt ttaccaatgt caatgcaagt tctaattgga
     4501 acgatccatg aacagaaggc ttgaaatgac aacaaaaaag ccgacaaaat attctcctcg
     4561 gcttttttct gatggttttc tattatgaat ttttcatgta ttgaaaaact gacttatatt
     4621 ccctcgtact ggatgtgttt gctccctata ctcaccattc gtatagcttc caatgacctt
     4681 gcgccaaaag gattgggctg gtctattcgt gctcatctga gtcaccttcc atcgcccatt
     4741 aaaacgtcca aacagctcat gagccgccca agtgcccacg ccattgtgtc gataaggacg
     4801 aagtacaaag aactcagcca tgtaatagtc agcttctcga ttgctagaca ttcggtcaac
     4861 gagtgcaaag cccacaggaa tatcctgtct ccagatcaaa aaaggcagct tttgttcgcc
     4921 gctcgtccag tattgataca agtctggata agccgggaat gtccccttct cagtgacatc
     4981 aattcgcaga taggctgtaa aatcgtataa gtaaaattgc atgagctgga caataatgtc
     5041 cttctgcgac tctggtacac tctttatgga cagcttcaat tctgatttga tattatatcc
     5101 catactttca cctctcttgg cggtcagctt gttctttact ttgattactc ccatccagtg
     5161 ctgttcaaaa tatgctaaaa tacatgtatt atgaccggac gaggtgaacc ctatgaacat
     5221 acaaaagatc atcgaccggc gcaaactgga tgaaaagttg ccggatttgc catggtacgt
     5281 acagcaattt atggattaca agcttcccga cctatccccc tctactttgc tggaatatgt
     5341 gcgggattac gaagcttttt tttcatggct tcgctcggaa ggcttgtctg ccggagaaac
     5401 gaatgcccaa gtgacactgg aagaattaga gacactccat atggatagca ttacaggttt
     5461 tcgtttgttc ctgtctacca aacgcgaagg ctccaattcc cgcatcacca tttcacgtaa
     5521 gctatcgtcc ttgcgttcac tctttcatta tttgagccaa atcgctgagg atgaaaactt
     5581 ttatccgttg ctcaagcgca atattatggc caaagtcgaa attaagcgcg tacataaacc
     5641 caaggatacg gccgccaagc tcaaagggaa aatactggaa gaggaagaac tgcttgaatt
     5701 tatcggctat atttatgaag gctatggaca agatttggct gataacaagc aagccctata
     5761 ctcctatgaa ttgaacaagg agcgagatgc ctgtatcgca agtcttattc tgaactcggg
     5821 actgcgtgta tccgaaatcg tcaacttgaa catggacgat ctcgatataa acaataaatt
     5881 gctgtatgtg taccgtaaag gaaataacga tgaaactttt aaaacgccag tatatttccg
     5941 cgagcaatcc aaagatgatc tcgcacttta tttatcctta agacataccc gttatcgcgc
     6001 tccaaaaaaa gaaaaagctc tttttgtcgc gcgacccaac ggcagtgctg agggcaaacg
     6061 gatgactaaa agagcgattc aagcaatgat catcaaatac gccaagcggt tcggcaagcc
     6121 ctatttgacc gttcacaagc tccgtcattc ctttgctaca gactattatt tacaaaatga
     6181 tatttacaaa accaaggaac agctgggtca cgcttcgaca gaaacaacgg aagtctatgc
     6241 ccacctgact gacaaaacga tgtctcaggc gatcgaacga cggatagaga ctcagactga
     6301 ctccgctaat tagtagccct ctcatccctg ctctgtctgg aatcccattt tgtgcctctg
     6361 aatctgttcg agtagccagc agcctgccgg ttcactggca tcggcaggaa atatttgcac
     6421 cgtttgttca tctgagtagt agtcctgagc ccaatccatg tggtactccc aaactactac
     6481 tccctgtaca tttgtcagtt cctgaacaag ctgcgcatcc gattgttccc gcaccatgat
     6541 cagcttcgga tatttttcct gcttgaaacc ttccagcaac acacagtcat aggcctgaaa
     6601 atgccggatg agtccgatca caggccgact atgttcctct aaaatggcag ttcttcctgc
     6661 cgaaacaatc gctacgcctt cggcacccgc ctgtcggtgc ttatacgtat ctgtcccctc
     6721 atgatccatc tcaaattcat gaccatcatg cttgatcaca gctacacgca gtcctgactg
     6781 ctgcgcataa cgaatcaaac ctccgaggaa ggttgttttt cctgtatttt tgaatccgac
     6841 gatttgacat acaaatggat atttcgtttt cacgtcacct gtccgccttg aagcaccagt
     6901 acgtgcacct cttcaccttc gtgcaagcct tctgttgtgg gaggaactac gatcagacaa
     6961 tcgctgtcct taatcgtaac catagcactg gattcatcta ctcgcgcagg aatcgcatat
     7021 acttgcccac tacgtatctc cagagaactg cgtacaaagc gggtatagtt gtttaccttc
     7081 gtataatctg ctcctagctt cgccgtccag gtttgcaaat acggatgtgc cgaagataac
     7141 atcatttgaa tagttggtcg tacaaacagc tcacagccta caaagcatgc accgggattg
     7201 ccagagagcg caaataacag cttaccgtct atcactgcgg ctgtggttac actacctgga
     7261 cgcatcgtaa ccttgttgaa cagcatattc acatcttcct gtcgtacgag atcacccata
     7321 atatcaaaat cacccaccga cactccacca ctcgtaacca caatatcata ggcagctatc
     7381 gcttctcgga cagaagcacg agcaaggttc aaatcatcat gaatggcttg cagaatgaac
     7441 ggctctcctc ctgcctctct aatttgagaa gccagcatat atgtattact gtttcgaatt
     7501 ttccccggtt gtaacggctc atccactgcg agcaattctg atccagtgga aaagacagcc
     7561 acccttggct tcttgtaaac aggcacccga tgtacaccaa aagtagccag taccgagaca
     7621 tgccccgctc ccacgcaagt tcccttactg agcaaaagct gaccttcctt aatctcatga
     7681 ccaatttgtg tcacattttt gccaacttcc atacgcttct tcaagccaac atatgtctgt
     7741 ccattttcct cacgcagctg tgtcgcctcc agcatcacca ccgtgtccgc tccttcaggt
     7801 agttgtgctc ctgtcatgat gcggactgcc attcccgtct ccacccgctt gtccgatacg
     7861 gtgccacaag gaatttcatc aatcacgtgt agccagattt cctgaccggt cgaacagact
     7921 tcagtgtccg aggcaaggat cgcatagccg tccataccag aacgacgaaa gcggggatac
     7981 ggatgtggcg cagtcaaatc catcgccaga tagcgaccat gtgcttgctc gagccctacg
     8041 tcctcccttt caccctgttg aacatagcta gctatcctgc tttgtgcttc ttccacctta
     8101 actgctttac gttggaattt ttctgtgttt aatggcgtct gattcatgtt ctcactccgt
     8161 tcttctaaaa taccctcttt ctgttataac gctaaaaccg ttatctggca aatccgaacg
     8221 gtgtttattg gatactgcaa gtctctatcc gccaaaaaac agcctgaata tcatatcgcg
     8281 gctgtttttg gtagattttg cttttttgtt ttgcatgtca ttacgtcagt tttctacgta
     8341 tattaagtta gattattttt accgaaatag attgaatcta ttgaaacctc atacaacgag
     8401 gacatttgct gcgctcgagc tattgttaaa tccgatgaat cttcctctat atgttttaat
     8461 tcattcattg acataccaag tatattgcaa gctattaact cactataacc tgaagcgagt
     8521 cgtgccatct ttattgtata aaagctagtg caagttacat tttcattttt atctgcaacc
     8581 atccaatcaa ctccacaata taattgataa aaaagtaatt tacctgtata ctctgaacga
     8641 aacacttttc ccctgttagg agcaagtaag gtgcaaaaac ttactcgggg gaaatgcctt
     8701 ttgaaagagg agctcaaatc tcatggacgc actcaatcat ggctcgcccg acgaactgga
     8761 tattcgcggc aacaaatatc caactggatc gcgggacgtg acaaaatgtc attcgaggcg
     8821 gcagtcctca tttctaggat attggagtgt aaagctgagg acttatatga gtgggaactt
     8881 gcctgacaaa caggcatttc cttcgggccg tttgtacatg ccggcattta cattatatat
     8941 cccgctttca ccctcctttt cttatatgta gattgttttt accttaattt aaaagattgt
     9001 tatttttttc ataatcaaat tttatcacat agaaaatgat taaaaacggg aaatatgtcg
     9061 aattaaatcg aacccgtccg gcttatccta gtctaactga ttattgactt attcatttaa
     9121 atctggtaac aaaaatgacc cctgaatttt catgggtcat ttccacaatt ttttaagtgc
     9181 tttaagttta ttatgagaca tcgagcaagt gaagtctgat cctttgaatc gtaccaaacc
     9241 tccaaatgcg ttagactcaa tctcacaaac caattctagg tttatcaggg tgtctttata
     9301 agcaggatat agatacggaa aagcttccct gcaagcttgt gcggttagcc cgattgaata
     9361 agaacgatct ccagagtgaa aacgcgggac ataataattt tttttaggtt cccacatatc
     9421 cacactaagc atattcccta ctttaaaaaa accgctcact gccgctttac ccactacctt
     9481 aatttccgat ccgaaaatat aacgaatttc tctatcggca ttcattgcat tctcatatat
     9541 ttgtttccat cgagataaat ttgctgaatt tatactttct ttaatgtttt gatttttaaa
     9601 aacaacctgc ccccctccat aatctcccgt aacgatcttg tccacttgtg tgatgttaac
     9661 caaattagat ccgtccaaat tgcaaaaagt gggtaagcct acggaacatt catggagggt
     9721 ggtgggaact gtaaatcttc catgagaagt atgaaaaagc gggatgtgat aattgctttt
     9781 aggcttccac aattcaatcg caactaggtg attctcacaa aaaaaagagc aatctccaag
     9841 tgaattgtca tcaagcaatg gagtagctag gattcgcttt ccctcttcca ttaaattcag
     9901 ttcttttctg ttttcttcag ctcagctggt acaggtttag cgccaaaaat tgttttttct
     9961 tttttggtag actcgttagc gtaattacca aggcttatac ttaaagctct cgccaatttc
    10021 ttatccattt tcgctcacct cctttccata aaggaagaat actgaatgct tgtataatta
    10081 aagataaaca tattatgtga gattgtataa aaaaatttaa tatgcaaacc aaaatacata
    10141 tcgttttata atatttgtga tgtttggtct tgttaatata gataaaatga ttgggagcat
    10201 atactacaaa cattaataat gaacaagcgt taattatcaa aatcgttgat aaacttaaag
    10261 agacgaaagg tatagttaca catatggccg ttgtaaaaca gacacaaagg gtaaggttgc
    10321 tgaagtgtac ccctcctgaa aatctcctta caaacatgat cgtagccagg gctagtaatg
    10381 ccccccaaaa atgtcctgtt atccaggcca taactgcgac cataagtact gccgaaattt
    10441 cggtcatttt cacaccaatc gcatactcca tcacttctac acttgtaggt ccatcaggat
    10501 cagctttctt tatttctgat gcgatgtgcc tcgatagcgt ttctagcatc ctcgtaatct
    10561 cctttctctg ataagaagta cgaaattcca aaagtcagca atgagatgga aagtagtcct
    10621 atcgtattgg agttatagag catatacaaa gtaacaagaa tcgtgacaaa tgatattaag
    10681 gagcctataa tgaacatttt attaaggggt gataggtaat tttcaccttt caaaaaatca
    10741 tgtgggggct gaatgataaa tgagaaacca aagttgtatt tccccatgac aaaagaaata
    10801 aagtacgcag taaaaataga agctagctgt ataacgtaaa tggaagagcc agctgtatca
    10861 cttataacgc ccggttgtgc tactccgaaa aagtttgcaa agatatatac aaatagctgt
    10921 agattaatgt aagctgtaag accggaacca gcagaaaaag ccgcaagata tgttttgatc
    10981 cctaaaccaa atcttaaaaa gagaaccatt aacaaatact gaagcggaaa atcaaattta
    11041 ggcatgccta taacttctct catgagaaag gaaaacaagg ctatgcccat tgcatagaaa
    11101 attatttttc ttcgattttc ccacacggga agcatataaa gcttcaagac caaagtaact
    11161 gccgctaaag catcgaaaaa accaagtata atatataaga aagcagataa cacagttaca
    11221 tcatcctcct atttcgcctg atgtaattgt atattttact aatagatgtg gcaataaaat
    11281 aatctagtaa attggaattt tttgtatgaa tatgagatga aattttcttc cactggcttt
    11341 ctttttcaaa ctcgacatcc attcgtgcta ataaaaaaag tcaccccaag tgagcgacgt
    11401 tgcttttgcc aatgtattat gttggttttt tttcgatatc aaggttataa tctacttaat
    11461 ttggggtgga gggattattg tggctttaag tgacaatttt aaaaaattac gtataaaata
    11521 tcatttgact caacaagagc ttgctgagat cgctggggtt accaataaag caatttcagc
    11581 ttgggagagc ggactttctg aaccacggat gggtgctata gaaaagatag ctcgtcatct
    11641 ccatatcaaa aaaagcaata tcattgaaga agatggcatt gagcacataa gccctgatcg
    11701 caggtcaaag tagacggcaa taaaatcgaa gtgagggaac atccattcaa tttaccttag
    11761 taaatgttaa acaacaaaaa aggaactggg caagacagtt ccacagttcc gcaaacaact
    11821 ttagaagaaa ataaaatatt acctattatc gtcgacttcg ccggctaatt ttacctgagc
    11881 cgctgcgtgt tttaggctta ctataagatt tgcgtggtga atcaaatatg ctggaaccac
    11941 cgctgctgcc tcggtcacgt gaaatcgaac ctctgctcgg tgaactgctg gagcctcgat
    12001 cgaatagact tccgcttgat ccaacgctgg aatccgaatt tttccctcta cgggtaactg
    12061 aaccttttcg ttccaccgtt atcggcggaa tcgctttttt ctcctgtgct gttggagcac
    12121 gatattgccc ttgtgaaggt cggtatacat ctctgctcga ataacctcga taggagccag
    12181 acccccgcaa tgaatcgaac agagcatcca gcacagttgc agttaagtat ccttttagaa
    12241 agctggaact gtaattttgc tcgacatact ttttactgtc gatttcaatg agtgtatctt
    12301 ccttcttagc tggatcttgc tgcaaatggt accattcatc gctatatacc agaaacatcc
    12361 gctcattgct ctgaggcgat atttgttccg gtgtacgctg ttctttcaat tcctccgcta
    12421 cttcgggaac cgttttgcct gccgcccgat atacgtacga ggtcgagttt ccgctaccac
    12481 taacggattc cagcggatac gtatctttca catttggcgc cccgcagccg cttagcacgg
    12541 atacgaacaa gctcagcgcc acaatgacct ttaatgcata ttgccaggtg cgtttgccca
    12601 tgtgtaaccc tctcctagct agcccgaata accttgacgt ctccggtaat cacttcttct
    12661 ccttcataaa gcataaagcg accgtcctgc cactctaccc gcagtagatg gtaatcatca
    12721 gactggtact gccaaacatg ttgctctcca ccctgccgga aaggagcacg gcccataacg
    12781 gtaacatgcc caaaatactg ttcttccaaa tgatacgttg tatcatccag ttctaaaatg
    12841 gtcggtactt cctccgggtt gtctagtctg ccatcgatag cctgatatag tccgaattgc
    12901 agtgtttccc gttcctcaat atgaagataa ctcacttgat taccatcctg aagcgtcaaa
    12961 acaacggcat tccgggcacg attatgtaca cgacctacca cttcataggt gacaagcgac
    13021 acttcacaaa tatccccagg atttaagtga agcatgcttt tttccgcttt cggcggttca
    13081 ggcttggcaa atagatttga aattcgtttc catacactca tggtcatatt tcctccttac
    13141 tttgcctaga agcatgctgt aatgatcaag gcacccacca aatgcagcgc tcctgaaaac
    13201 agaccgaaac caattttacc ttcttgggta cctttgtcca gatcaaactg tgcccagtac
    13261 cgcaacagca gacgcacaat cacttccaaa acaagcaaga tgataaaggc aatcacagaa
    13321 tacacaagcg cttcgagcaa attattagct gtagcaattg aacccgataa aatgtatcct
    13381 tgtgcaatca gcttcataat catccggact gttacagcca tatttccagc ttttacttcg
    13441 gcgaaatcct tatactttgt aaataaagaa tcgacataca ttaatacgaa cagcaaaata
    13501 gcacctgcgc ccgtccatac cagcatcgct ttcatcgttt ctaaaaaatg catttgctac
    13561 catcctccac atcttcttga ctacatatat tcatttacgc ccccaggcag ggaaaagcga
    13621 aggagataac gtttctcctt cgcttactga gccaccacac tagcggcaat gcttaaaagt
    13681 tcttatttgt tttcgtattg tttcagcaaa gcagcaagtt cgtcgtccac agcacttttc
    13741 ttatccagct ctttgaactc ttcatccagc gatttttcct tggaagccat ttcgttgctc
    13801 gcttcagcac gtgcttctgc ttgcagcatt ttttcctcca tacgctttaa tccagcagtt
    13861 gccgtatccg agctaaaacc attcatcgct ttgttaattt cagtttgcgc tttagctgca
    13921 ttataacggg caaccagtgt ctcgcgcttg tttttcattt cagtcagctg tctgcgcatt
    13981 tcatccagct taccacgcag gttgtcagct gcagctttgt tttgttcata accagcttgg
    14041 aactcgttca ttttttgttc ggcagatttc ttttcttcca gcgcacgacg agcaagatcc
    14101 acattttgtg cttttgcagc cgtatgagcc tgttcttcgc gttttttcac caaagctgcc
    14161 tgttcttcgt attgctgttt aaatctcttt tcaatagcaa tttgagcggc taccgctttc
    14221 tctgcgtctt ccagatcctc ttgcatatca cgaatgtatt gatccgtcat tttaactgga
    14281 tcttctgcct tgtcgataat ggcgttaatg ttagacatcg taagatctct taatcgtttg
    14341 aaaatagaca tgtgaagttc ctcctagaat tgaatgctta aattttaagc tctgtacaca
    14401 tgtttacgca agctttgcaa agaggtttca aaaatatcta aaaaccgcgt agataaggct
    14461 ctggaatatc cgcctgtact tttagcgccc gtgatgcatg cagcgcccaa tagggatcac
    14521 gcagcatggc acgccctacg gctaccagat cagcttcatt gtgctgaacg actcggcggg
    14581 catcctcata atcatccaat aagccgacag caatgacagg cacattcaat ttctcacgga
    14641 tggtatgagc caaatccacc tgataaccag cacgcgcaga cggacctccg ctggaaccaa
    14701 tcggaccctc accaccagaa gaaatatgga aaatgtctac acccgcatca cgatatcgtt
    14761 cccctatggc tgctatgtat tcaacatcat atccgtcttg gacatattct ttggcagata
    14821 tccgcattag cacaggcata tcagcaggaa gcacctcttt aacagcacgt atcacctcaa
    14881 caccaaacag tgataaatcc tgcccatact catcttctcg ggtattggtt aaaggagaat
    14941 gaaattgatg gattagatag ccgtgagcgc catgaatctc taccgtgtca aaaccagctt
    15001 ctaccgcccg gcgcgccccc tctttgtagg caagaaccag ttccttgact tctgctcgcg
    15061 tcaaagcgtg cggctcttta aatcgttcac taaaggggat cgaggacggg cctacaggtg
    15121 gctcagcatc ttcagccttg cgtccggcat ggcctaattg aatggcaatt ttggcaccat
    15181 acttgtggac ttcctctacc attttacgat atgcaggaat atgttcatca ctccaaatgc
    15241 ccaaatcacg atccgtaatg cgcccatccg gatgaaccgc tgtcatttcc acaattatga
    15301 gtccagtccc tcctaccgcg cgactcacat aatggacata atgccaatcc gtcggtttgc
    15361 cgtccttggc ctccacgctg tattggcaca ttgggggcat gacaatccga tttcttaaag
    15421 aaagcccctt taattgataa ggagtaaaca agtcggtcac ttttatccat ccttccctca
    15481 attccaagtc tgtagcatta tgaatagcat ccccattata caccagctgt cacggtatac
    15541 cgaatccttt gtaaggctga aacttacgaa aatgctccag ttttcgttca tgtttaagag
    15601 aatatgcgcg tttacttcgt catcttcacg gatatccgct tcatgatgtg cttctcttca
    15661 gtcgtgtagg acttcactca atcaccagca taattttaat aggacaggta cataatagct
    15721 gagagcacca ctaggtacca ctgcacggaa agggggaata caaatgcggt acaggggagt
    15781 gttgccatgt ttagcactgt tactagcatt ttcaagtttt cccgttcacg ctgacacgcc
    15841 tcccaacatc ggaacgcccc atcgcaagga agctactgtc gctacttcgg tatatcaaag
    15901 taaagatcga gctactccaa cattagcgat gctacgaaaa aagcatgcgg acatttttaa
    15961 aatgtgcggc ccgcacaccc gccaaattgc cttaaccttt gatgatgtgc ccgattcaag
    16021 gtatacgccg caggttttgg acgtattaca cgcaaacggt atcaaagcta cgttttttat
    16081 cgtcggccat cgtgcggaaa agcatccggg gattatacgc cgcatcatcc gcgagggtca
    16141 tgctatagga aaccattcct atactcatcc ggatttcagg aaggccacac cagaacgctt
    16201 tcgccaccag attacaaaaa cagaacgcat tttagaagcc agcgcaggtt ttcggcccag
    16261 attgatacga ccaccctatg gtgaaatcac ggagcctcaa attcagtggg cgcgtcgtca
    16321 tgggtacatg atcgtcaatt ggaatgtgga ctctctagac tggaagggat taagcaaaac
    16381 acagattcag cgtaacgtga tcccggcaac cagacctggc tccattattt taatgcatgc
    16441 aggtggaggt caaagttcca acttgcaagg tactgtccaa gctttgccgg gtctaatcca
    16501 ctctttaaaa gctaagggct acaagtttgt cacagtcccc cggctacttc acacatcgga
    16561 acgaaaataa cagtatgtct aagcctcgta tataccaaca acgtaaaaag gctgccttga
    16621 cgagcagaat gcttctgctt gtaagacagc cttttttagc gataaacgac cgtactggta
    16681 agaagtcgtc ccagttatat gttgtgtgct ataatattaa gtttacataa tatatattat
    16741 gtttaatgaa atcaaatata tgcacaatgc tatttatcaa taacgtacag tttcacattt
    16801 tggaagccga agtcgttcac gaatgatttg ttgccaggga taaagatatc aatccgcttt
    16861 ccggtaatag cgctgccctg atcacgggca acggctacaa aagaatggtc tggcaagccg
    16921 ggatgggaat agcctgtaac tagcaccttt gttcccatag gaatgacttt cgggtctact
    16981 gcaattgtac ccagtttaag cggattaccg tagtaatcga ctgcacccca tttgccattt
    17041 tcatcagctg cggctgaata tgctgttgct ttaacatcaa caactttact gtaattgaat
    17101 gttttgcccc atgcttcaat tgttggcctc tcattcgctg gtgctttctc cgtaagaagc
    17161 tgtggtttcg aatccgaagc cgccttcaca cttttttcgt ctggcacttt aatttgtaga
    17221 cctgcatata tgttgttgga cgcaatatcc gggttagcct tcgtcaagtc atctaccgat
    17281 accccataac gttgagcaag caaaaagaaa gtatcgcctt ctttggcagt atgaagcgaa
    17341 gcagcatttg ctactccagc tgtctgtgcc aatcctgcaa tcgctgcggc aagcaccgca
    17401 aatttcatgg tttttccaat atgttttaag tgtttcaaag atatgtacct cctctgttat
    17461 gcctgcgaag ttagctgtcg gattcggact caggagaagc cctatgcttg tgcaattcac
    17521 ccctaggcat attccacaac atctatatga cgcattggaa taattgccgt tgttacgtcc
    17581 cccgcacttc ccatggtttg agcccagcac ctgagtaatt gttatcattg ctgctgcccc
    17641 ggtaagtttt ggcttactgc ataatatcac aattttgtaa ccttatctgc atgaaaatgt
    17701 tgggaacctt gaacatcata ctatatccat tacaattttg tcatcaaaaa tcggtttttt
    17761 gttacgaaaa tatggagata tggtgacaaa aggagaaaag ccctccgtga aatatctgaa
    17821 ctgtgacccc aactgaggac actttgaata aagcccgctt aagcagccaa tagatggctt
    17881 ctgaattcgt caggagtcat cttttttaac gcccattggt agcggcctga gttgtagtaa
    17941 gcaatgtagt tatcgatgca tgcccgtaat tcttgaatgg ttgcgcacga tttgtattcc
    18001 agatcatcct tcatatgacc gaagaatgtt tccatagagg cattgtccca acaatttccc
    18061 ttccgagaca tagactgcct gaagcctgct ttacggacca gaaggcgaat tttggggtgg
    18121 gtatagtgca tgccttggtc agagtgcaag atggcctcag gatgaacatt gccatcgaac
    18181 cgttcaatta acaactgcag cgtccgctcc accaagacga gctccagaga agatgacaga
    18241 tagtgagcaa gtatctgctt ggttgcccca tccttcacac aagacaagta ggcacactgc
    18301 ccgtgaccat agtgcaaata ggtgatatct gtgagcaata ctttttctgg ttccccttgg
    18361 tcaaactgac gttttagcag gttggggcat gtctggtgtt cctgagtcgc cttggccatt
    18421 ttacggtatg gattagcttg ccgaatcgtg gcgacaagtt tgtacgttcg catgatccgt
    18481 cggatctttt tgtggttcat agtaacacca ttttcccgtt caagcctcat tttaatcacc
    18541 aatgctcctg ctttgccatg tagggcataa aaatgcatct tgatgagcgc taagtcatgt
    18601 tcatctgcgc gagcttgcaa ctggcgtctc tcctcggcat gaagccagcg gtaatagccg
    18661 cttgcactga tgtgagacag ttcgcacagg tagcgtgtca tgcgctttag gctatgttgt
    18721 cggatcgtga ggttgattat ctgatagcgc tcggagggtg tcaacgtttc ctctgcatct
    18781 tctgcttttc gagcgcttcg agctttttta ggaagtcatt ctccgcttca agcaacttga
    18841 tgcgcgcttc ggcacgcttc agtttttctt ctgtggacaa gttgtttgtc tgcggtctgc
    18901 ccacacttcc tttccctcgt tgctcctcta aaagagaggc ctctccatgg gcagcataga
    18961 tatttcgcca acgatataag cttttctttg gcttttcgtg tccaatggtg tcgatgtcaa
    19021 aacccgccct aagaaaaata tccatcggcg tctgtccggc ttcataagct tttaccgctt
    19081 ccaccttaaa ctctggggcg taagtgatgg ttttgtccgt cactttttgc acatttggat
    19141 tagcctcgag ctgtttaatc tcttgttcgc taaagatttt ggaagcacct ctcttattgc
    19201 tcatgaatct tacctcacaa tcctctttat ggtttgatta aaacacaaat gacccgtaag
    19261 tgggtcactt ttttcaaagt gtccatctta cgggtcacag ttcaatcatc acgagagggc
    19321 tttgtcaata attcataaaa gcattttctt atagcacttt agccagaaaa tcacgggtac
    19381 gatcatggct tggagttccg aaaacttgct ccggcgtacc ttgctcaata atttgaccgt
    19441 tgtccataaa gatgattcgg tctcctacct cacgagcaaa gcccatttca tgcgtcacga
    19501 tcaccatcgt catgccgcct tcagcgagct tcttcatcac atccagaacc tctccaacca
    19561 tttcagggtc cagggcagag gtaggttcat caaacagcat tacgtgcggc tgcatggcga
    19621 gagcacgtgc tatcgctata cgttgctttt gaccgccaga taactggttc gggtaggtat
    19681 tcttcttatc ctcaagaccc acggtccgca ggagctccaa cgcaattttc tccgcttctt
    19741 tccccgattg cttcttcacc tgcgttggtg caagcgtcag attctgcagt gttgttttat
    19801 gcggaaacaa attaaaatgt tggaaaacca tccccatctt ctctcgagtc gcattaatat
    19861 tatgaccacg ggccgtaatc ggctcaccct caaacaagat ttccccttct gttggctgtt
    19921 ccaacagatt catacaacgc aaaaacgtac ttttccccga accactcggg ccgataatga
    19981 cgactacttc acctttggcg atatctatat caatgccttt taaaatttca ttcttaccga
    20041 atgatttacg cagttgttta acggtgatca ctggctctca acttcctttc ccataaaccc
    20101 aacagcttag ataagctgaa tgtcattaca aaataaatag cggctgcgat tacgaatgga
    20161 cttaagcctt cgtaggtaat attcttaatg acctgggctt gatacataat gtccaccatc
    20221 ccaatggtcg aaataataga agattcttta atgatcgtaa tgaactcatt accaatagca
    20281 ggcaatatag atttaaatgc ttgcggtaaa ataacgtgac gcatcgcttt gcctcgtccc
    20341 atcccgagcg agcgggcagc ttccatctgt ccacggtcta cggcctgaat accagcacgg
    20401 aaaatttcag ccaaatatgc cgaactattc agagacaacg taattatacc ggactggagt
    20461 ggcgtaaaat taacacctaa cgtcaaagca actccgtaat gaatgatcat aagctgcacc
    20521 agcataggtg tgccgcgcag tatctctac
//
