Select genomic region:
Overview
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1.3
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1.5
1.6
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1.9

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP101913.1 (Oceanobacillus oncorhynchi)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1 | terpene | 289,377 | 311,251 |
Region 2 | terpene | 924,858 | 945,679 |
Region 3 | hserlactone | 966,209 | 986,643 |
Region 4 | lanthipeptide-class-ii | 1,816,628 | 1,842,993 |
Region 5 | ectoine | 2,018,520 | 2,028,906 | Medium | ectoine | other:other
Region 6 | terpene-precursor | 2,776,402 | 2,797,289 |
Region 7 | T3PKS | 3,272,235 | 3,313,401 |
Region 8 | terpene-precursor | 3,426,712 | 3,449,024 |
Region 9 | RiPP-like | 3,554,665 | 3,564,967 |

NZ_CP101913.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 289,377 - 311,251 nt. (total: 21,875 nt) Show pHMM detection rules used
terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
NP440_RS01580: short-chain dehydrogenase/reductase SDR

smcogs
  SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: aminotransferase
NP440_RS01665: aminotransferase

smcogs
  SMCOG1019: aminotransferase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002173.2 |  | 0.47 | saccharide, terpene | fumihopaside A, compound 3, 21-β-H-hopane-3beta, 22-diol | Aspergillus fumigatus A1163
BGC0001317.3 |  | 0.42 | terpene | lupeol | Lotus japonicus
BGC0001314.3 |  | 0.38 | terpene | tirucalla | Arabidopsis thaliana
BGC0000670.4 |  | 0.37 | terpene | thalianol, thaliandiol, thalianin | Arabidopsis thaliana
BGC0001768.4 |  | 0.35 | NRPS | sansalvamide | [Nectria] haematococca mpVI 77-13-4
BGC0002138.2 |  | 0.35 | PKS | fuelimycin A, fuelimicin B, fuelimicin C | Streptomyces albireticuli NRRL B-1670
BGC0001197.5 |  | 0.33 | PKS | frankiamicin | Frankia sp. EAN1pec
BGC0000391.5 |  | 0.33 | NRPS | methylpendolmycin, pendolmycin | Marinactinospora thermotolerans
BGC0000663.5 |  | 0.32 | terpene | hopene | Streptomyces coelicolor A3(2)
BGC0000204.5 |  | 0.31 | PKS | benastatin A, benastatin B, BE-43767, TAN1532B | Streptomyces sp. A2991200

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002173.2 |  | 0.47 | saccharide, terpene | fumihopaside A, compound 3, 21-β-H-hopane-3beta, 22-diol | Aspergillus fumigatus A1163
BGC0001317.3 |  | 0.42 | terpene | lupeol | Lotus japonicus
BGC0001314.3 |  | 0.38 | terpene | tirucalla | Arabidopsis thaliana
BGC0000670.4 |  | 0.37 | terpene | thalianol, thaliandiol, thalianin | Arabidopsis thaliana
BGC0001768.4 |  | 0.35 | NRPS | sansalvamide | [Nectria] haematococca mpVI 77-13-4
BGC0002138.2 |  | 0.35 | PKS | fuelimycin A, fuelimicin B, fuelimicin C | Streptomyces albireticuli NRRL B-1670
BGC0001197.5 |  | 0.33 | PKS | frankiamicin | Frankia sp. EAN1pec
BGC0000391.5 |  | 0.33 | NRPS | methylpendolmycin, pendolmycin | Marinactinospora thermotolerans
BGC0000663.5 |  | 0.32 | terpene | hopene | Streptomyces coelicolor A3(2)
BGC0000204.5 |  | 0.31 | PKS | benastatin A, benastatin B, BE-43767, TAN1532B | Streptomyces sp. A2991200

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
triterpene | hopanoid |  | C30 | hopanoid skeleton | unknown
triterpene | polypodane |  | C30 | polypodane skeleton | unknown

Genes with terpene domains:
NP440_RS01605: T2TS
Domain 1 (3 - 622): Type 2 terpene synthase
Subtype: Squalene substrate

Reactions:
  squalene → hopanoid
  squalene → polypodane

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 24.02 out of 26.06
Confidence: medium
Additional weak hits (1):
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.51 out of 29.38
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.
No acronyms to display
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
MogR | Repressor of flagellar motility genes

NZ_CP101913.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 924,858 - 945,679 nt. (total: 20,822 nt) Show pHMM detection rules used
terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Transferases: carbamoyltransferase phosphorylase
NP440_RS04615: ornithine carbamoyltransferase

smcogs
  SMCOG1114: ornithine carbamoyltransferase

NP440_RS04670: thiamine-phosphate pyrophosphorylase

smcogs
  SMCOG1280: thiamine-phosphate pyrophosphorylase

Ligases: synthase
NP440_RS04635: cysteine synthase

smcogs
  SMCOG1081: cysteine synthase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001226.4 |  | 0.43 | ribosomal | streptocollin | Streptomyces collinus Tu 365
BGC0000563.4 |  | 0.42 | ribosomal | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000616.4 |  | 0.40 | ribosomal | amylocyclicin | Bacillus velezensis FZB42
BGC0001579.4 |  | 0.40 | ribosomal | duramycin | Streptomyces cinnamoneus
BGC0000883.5 |  | 0.39 | other (other) | arginomycin | Streptomyces arginensis
BGC0001660.3 |  | 0.37 | ribosomal | mathermycin | Marinactinospora thermotolerans
BGC0000542.3 |  | 0.37 | ribosomal | paenicidin B | Paenibacillus terrae
BGC0000579.4 |  | 0.31 | ribosomal | SSV-2083 | Streptomyces sviceus ATCC 29083
BGC0000503.5 |  | 0.31 | ribosomal | cinnamycin | Streptomyces cinnamoneus
BGC0000926.5 |  | 0.31 | other (other) | rhizocticin A | Bacillus subtilis subsp. spizizenii ATCC 6633

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001226.4 |  | 0.43 | ribosomal | streptocollin | Streptomyces collinus Tu 365
BGC0000563.4 |  | 0.42 | ribosomal | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000616.4 |  | 0.40 | ribosomal | amylocyclicin | Bacillus velezensis FZB42
BGC0001579.4 |  | 0.40 | ribosomal | duramycin | Streptomyces cinnamoneus
BGC0000883.5 |  | 0.39 | other (other) | arginomycin | Streptomyces arginensis
BGC0001660.3 |  | 0.37 | ribosomal | mathermycin | Marinactinospora thermotolerans
BGC0000542.3 |  | 0.37 | ribosomal | paenicidin B | Paenibacillus terrae
BGC0000579.4 |  | 0.31 | ribosomal | SSV-2083 | Streptomyces sviceus ATCC 29083
BGC0000503.5 |  | 0.31 | ribosomal | cinnamycin | Streptomyces cinnamoneus
BGC0000926.5 |  | 0.31 | other (other) | rhizocticin A | Bacillus subtilis subsp. spizizenii ATCC 6633

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
triterpene |  | squalene | C30 | acyclic | none
triterpene | C30 carotenoid | diapophytoene | C30 | acyclic | none
triterpene |  | PSPP | C30 | acyclic | PP
tetraterpene | C40 carotenoid | phytoene | C40 | acyclic | none
triterpene |  | hydroxysqualene | C30 | acyclic | OH

Genes with terpene domains:
NP440_RS04655: PT_phytoene_like
Domain 1 (14 - 232): Prenyltransferase; Phytoene synthase like
Subtype: unknown

Reactions:
  FPP → squalene
  FPP → diapophytoene
  FPP → PSPP
  GGPP → phytoene
  PSPP → hydroxysqualene

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57
Confidence: strong
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.40 out of 26.06
Confidence: medium
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 18.53 out of 20.97
Confidence: medium
ArcA
Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.05 out of 21.55
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 21.85 out of 27.78
Confidence: medium
MexT
Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 20.10 out of 21.84
Confidence: medium
CatR
Description: H2O2-responsive repressor
Species: Streptomyces coelicolor
Score: 21.07 out of 25.31
Confidence: medium
Additional weak hits (4):
CopR
Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 23.13 out of 30.97
Confidence: weak
VqsM
Description: Regulator of quorum-sensing signalling systems
Species: Pseudomonas aeruginosa PAO1
Score: 17.11 out of 20.47
Confidence: weak
ClgR
Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 20.73 out of 30.22
Confidence: weak
LexA variant 3
Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 23.71 out of 32.93
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
FPP | Farnesyl diphosphate
GGPP | Geranylgeranyl diphosphate
PP | Diphosphate
PSPP | Presqualene diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
ArcA | Repressor of carbon oxidation
CatR | H2O2-responsive repressor
CcpA | Catabolite control protein A
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
MexT | Global virulence regulator
MogR | Repressor of flagellar motility genes
ToxT | Regulator of MSHA biosynthesis

NZ_CP101913.1 - Region 3 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 966,209 - 986,643 nt. (total: 20,435 nt) Show pHMM detection rules used
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
NP440_RS04840: short-chain dehydrogenase/reductase SDR

smcogs
  SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: acetyltransferase
NP440_RS04850: GCN5-related N-acetyltransferase

smcogs
  SMCOG1111: GCN5-related N-acetyltransferase

Ligases: ligase
NP440_RS04910: AMP-dependent synthetase and ligase

smcogs
  SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002218.2 |  | 0.36 | terpene | (-)-Cyatha-3,12-diene | Dentipellis sp. KUC8613
BGC0001928.2 |  | 0.36 | other (other) | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000509.4 |  | 0.35 | ribosomal | epilancin 15x | Staphylococcus epidermidis
BGC0000812.3 |  | 0.35 | other (other) | huperzine A | Shiraia sp. slf14
BGC0001575.4 |  | 0.35 | NRPS | PZN5, PZN6, PZN7, PZN9, PZN10, PZN11 | Ruminococcus sp. 5_1_39BFAA
BGC0000671.3 |  | 0.35 | terpene | momilactone B | Oryza sativa Japonica Group
BGC0001605.3 |  | 0.34 | terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0002062.2 |  | 0.34 | PKS | agnestin A, agnestin B | Paecilomyces divaricatus
BGC0002719.2 |  | 0.34 | NRPS | thanafactin A | Pseudomonas fluorescens
BGC0002641.2 |  | 0.34 | NRPS | bacillothiazol A, bacillothiazol B, bacillothiazol C, bacillothiazol D, bacillothiazol E, bacillothiazol F, bacillothiazol G, bacillothiazol H, bacillothiazol I, bacillothiazol J, bacillothiazol K, bacillothiazol L, bacillothiazol M, bacillothiazol N | Bacillus velezensis FZB42

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002218.2 |  | 0.36 | terpene | (-)-Cyatha-3,12-diene | Dentipellis sp. KUC8613
BGC0001928.2 |  | 0.36 | other (other) | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000509.4 |  | 0.35 | ribosomal | epilancin 15x | Staphylococcus epidermidis
BGC0000812.3 |  | 0.35 | other (other) | huperzine A | Shiraia sp. slf14
BGC0001575.4 |  | 0.35 | NRPS | PZN5, PZN6, PZN7, PZN9, PZN10, PZN11 | Ruminococcus sp. 5_1_39BFAA
BGC0000671.3 |  | 0.35 | terpene | momilactone B | Oryza sativa Japonica Group
BGC0001605.3 |  | 0.34 | terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0002062.2 |  | 0.34 | PKS | agnestin A, agnestin B | Paecilomyces divaricatus
BGC0002719.2 |  | 0.34 | NRPS | thanafactin A | Pseudomonas fluorescens
BGC0002641.2 |  | 0.34 | NRPS | bacillothiazol A, bacillothiazol B, bacillothiazol C, bacillothiazol D, bacillothiazol E, bacillothiazol F, bacillothiazol G, bacillothiazol H, bacillothiazol I, bacillothiazol J, bacillothiazol K, bacillothiazol L, bacillothiazol M, bacillothiazol N | Bacillus velezensis FZB42

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.69 out of 26.06
Confidence: medium
AbrC3
Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 16.31 out of 18.16
Confidence: strong
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.78 out of 20.97
Confidence: strong
Additional weak hits (2):
LexA variant 1
Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 21.42 out of 29.65
Confidence: weak
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 19.13 out of 30.11
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
AbrC3 | Antibiotic production activator
CcpA | Catabolite control protein A
MogR | Repressor of flagellar motility genes

NZ_CP101913.1 - Region 4 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,816,628 - 1,842,993 nt. (total: 26,366 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lanthipeptides
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Lyases: cyclase
NP440_RS09130: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

NP440_RS09145: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-ii | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001210.5 |  | 0.50 | ribosomal | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000552.3 |  | 0.49 | ribosomal | SmbA, SmbB | Streptococcus mutans
BGC0001391.3 |  | 0.48 | ribosomal | thusin | Bacillus thuringiensis serovar rongseni
BGC0000626.3 |  | 0.47 | ribosomal | thuricin | Bacillus thuringiensis
BGC0001311.5 |  | 0.47 | ribosomal | flavecins | Ruminococcus flavefaciens FD-1
BGC0000527.5 |  | 0.46 | ribosomal | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000539.5 |  | 0.46 | ribosomal | nukacin ISK-1 | Staphylococcus warneri
BGC0000547.5 |  | 0.45 | ribosomal | salivaricin 9 | Streptococcus salivarius
BGC0000516.4 |  | 0.45 | ribosomal | geobacillin II | Geobacillus thermodenitrificans
BGC0000521.3 |  | 0.44 | ribosomal | lacticin 481 | Lactococcus lactis subsp. lactis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001210.5 |  | 0.50 | ribosomal | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000552.3 |  | 0.49 | ribosomal | SmbA, SmbB | Streptococcus mutans
BGC0001391.3 |  | 0.48 | ribosomal | thusin | Bacillus thuringiensis serovar rongseni
BGC0000626.3 |  | 0.47 | ribosomal | thuricin | Bacillus thuringiensis
BGC0001311.5 |  | 0.47 | ribosomal | flavecins | Ruminococcus flavefaciens FD-1
BGC0000527.5 |  | 0.46 | ribosomal | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000539.5 |  | 0.46 | ribosomal | nukacin ISK-1 | Staphylococcus warneri
BGC0000547.5 |  | 0.45 | ribosomal | salivaricin 9 | Streptococcus salivarius
BGC0000516.4 |  | 0.45 | ribosomal | geobacillin II | Geobacillus thermodenitrificans
BGC0000521.3 |  | 0.44 | ribosomal | lacticin 481 | Lactococcus lactis subsp. lactis

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for NP440_RS09130

NP440_RS09135
Leader:
MKEKDLQLFNTAGDFMSELEEASLKNISGG
Core:
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
Core with dehydrations:
A A E P M G I Dha E D N D G K Y Cys Dhb L Dhb W E Cys Dha I Cys P Dhb H Dhb Cys W Cys

#### antiSMASH-DB 4.0 matches for NP440_RS09135

100.0%
NZ_CP101913.1 and 1 other:
NZ_CP101913.1 Lanthipeptides: NP440_RS09135_lanthipeptide
Lanthipeptides: NP440_RS09135_lanthipeptide
1
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
1
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
90.6%
NZ_BOSN01000007.1 and 3 others:
NZ_BOSN01000007.1 Lanthipeptides: KJS43_RS18005_lanthipeptide NZ_JAHHXV010000040.1 Lanthipeptides: KM914_RS20960_lanthipeptide NZ_JAHHXV010000040.1 Lanthipeptides: KM914_RS20960_lanthipeptide
Lanthipeptides: KJS43_RS18005_lanthipeptide
1
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A A E P M G I S+ N D G K Y C T+T W E C S I C P T H T C W C
1
A A E P M G I S Q G N D G K Y C T I T W E C S I C P T H T C W C
32
87.5%
NZ_LT745762.1 and 1 other:
NZ_LT745762.1 Lanthipeptides: B2C77_RS00795_lanthipeptide
Lanthipeptides: B2C77_RS00795_lanthipeptide
1
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A A E P M G I S+ N D G K+C T+T W E C S I C P T H T C W C
1
A A E P M G I S Q G N D G K W C T V T W E C S I C P T H T C W C
32
with 100 more sequence matches
Only the first 10 are displayed here.
78.1%
NZ_BQME02000001.1 and 1 other:
NZ_BQME02000001.1 Lanthipeptides: MFF31_RS04105_lanthipeptide
Lanthipeptides: MFF31_RS04105_lanthipeptide
2
A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C-W C
32
A E G I S+ N D G K Y C T L T W E C S+C P T T C W C
1
A E Q R G I S Q G N D G K Y C T L T W E C S V C P T L T C F W C
32
78.1%
NZ_KV917378.1 and 1 other:
NZ_KV917378.1 Lanthipeptides: BK581_RS07320_lanthipeptide
Lanthipeptides: BK581_RS07320_lanthipeptide
2
A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A+ G I S+ N D G K Y C T+T W E C S I C P T H T C W C
1
A D V Q G I S Q G N D G K Y C T I T W E C S I C P T H T C W C
31
75.0%
NZ_CP063142.1 and 10 others:
NZ_CP063142.1 Lanthipeptides: HPB58_RS21475_lanthipeptide NZ_FOXX01000007.1 Lanthipeptides: BM012_RS26100_lanthipeptide NZ_JALAMS010000001.1 Lanthipeptides: MOC86_RS01460_lanthipeptide NZ_JALAMS010000001.1 Lanthipeptides: MOC86_RS01460_lanthipeptide NZ_LVYL01000023.1 Lanthipeptides: A3863_RS12035_lanthipeptide NZ_LVYL01000023.1 Lanthipeptides: A3863_RS12035_lanthipeptide NZ_LWAG01000015.1 Lanthipeptides: A4R27_RS06450_lanthipeptide NZ_LWAG01000015.1 Lanthipeptides: A4R27_RS06450_lanthipeptide NZ_LWAI01000057.1 Lanthipeptides: A4U60_RS22240_lanthipeptide NZ_LWAI01000057.1 Lanthipeptides: A4U60_RS22240_lanthipeptide
Lanthipeptides: HPB58_RS21475_lanthipeptide
2
A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A E G I S+ N D G C T+T W E C S I C P T H T C W C
1
A E Q R G I S Q G N D G H Q C T I T W E C S I C P T H T C W C
31
72.7%
NZ_FOXD01000022.1 and 1 other:
NZ_FOXD01000022.1 Lanthipeptides: BM124_RS15270_lanthipeptide
Lanthipeptides: BM124_RS15270_lanthipeptide
2
A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A E P G I S+ N D G Y C T+T W E C +C P T H T C W C
3
A E P R G I S Q G N D G D Y C T I T W E C G M C P T H T C W C
33
68.8%
NZ_JAMDLZ010000027.1:
Lanthipeptides: M5W82_RS15515_lanthipeptide
2
A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W
31
E I S+ N D G K+C T L T W E C S I C P T T C W
1
V E T K K I S K G N D G K W C T L T W E C S I C P T K T C W
30
68.8%
NZ_KQ040792.1 and 1 other:
NZ_KQ040792.1 Lanthipeptides: WH45_RS23330_lanthipeptide
Lanthipeptides: WH45_RS23330_lanthipeptide
2
A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A E G+S+ N D G K C T L T W E C +C P T H T C+C
1
A E V Q G L S Q G N D G K V C T L T W E C G L C P T H T C F C
31
63.6%
NZ_AUCI01000015.1 and 1 other:
NZ_AUCI01000015.1 Lanthipeptides: G475_RS0114640_lanthipeptide
Lanthipeptides: G475_RS0114640_lanthipeptide
2
A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
E G+S+ N D G Y C T+T W E C +C P T H T C W C
3
V E T R G L S Q G N D G D Y C T I T W E C G M C P T H T C W C
33
63.2%
NC_023073.1 and 73 others:
NC_023073.1 Lanthipeptides: U722_RS06170_lanthipeptide NZ_CP010556.1 Lanthipeptides: SB45_RS05930_lanthipeptide NZ_CP010556.1 Lanthipeptides: SB45_RS05930_lanthipeptide NZ_CP016371.1 Lanthipeptides: A5891_RS06120_lanthipeptide NZ_CP016371.1 Lanthipeptides: A5891_RS06120_lanthipeptide NZ_CP016395.1 Lanthipeptides: BBJ33_RS06540_lanthipeptide NZ_CP016395.1 Lanthipeptides: BBJ33_RS06540_lanthipeptide NZ_CP017775.1 Lanthipeptides: BK055_RS07100_lanthipeptide NZ_CP017775.1 Lanthipeptides: BK055_RS07100_lanthipeptide NZ_CP018295.1 Lanthipeptides: BHE96_RS06300_lanthipeptide NZ_CP018295.1 Lanthipeptides: BHE96_RS06300_lanthipeptide NZ_CP023075.1 Lanthipeptides: CK238_RS06735_lanthipeptide NZ_CP023075.1 Lanthipeptides: CK238_RS06735_lanthipeptide NZ_CP023133.1 Lanthipeptides: CJP14_RS04225_lanthipeptide NZ_CP023133.1 Lanthipeptides: CJP14_RS04225_lanthipeptide NZ_CP025341.1 Lanthipeptides: CXR48_RS06135_lanthipeptide NZ_CP025341.1 Lanthipeptides: CXR48_RS06135_lanthipeptide NZ_CP027429.1 Lanthipeptides: C6P48_RS12845_lanthipeptide NZ_CP027429.1 Lanthipeptides: C6P48_RS12845_lanthipeptide NZ_CP028440.1 Lanthipeptides: DA378_RS05125_lanthipeptide NZ_CP028440.1 Lanthipeptides: DA378_RS05125_lanthipeptide NZ_CP031694.1 Lanthipeptides: DXY21_RS18530_lanthipeptide NZ_CP031694.1 Lanthipeptides: DXY21_RS18530_lanthipeptide NZ_CP033967.1 Lanthipeptides: EG882_RS17885_lanthipeptide NZ_CP033967.1 Lanthipeptides: EG882_RS17885_lanthipeptide NZ_CP035393.1 Lanthipeptides: ES966_RS07170_lanthipeptide NZ_CP035393.1 Lanthipeptides: ES966_RS07170_lanthipeptide NZ_CP044133.1 Lanthipeptides: F3129_RS06725_lanthipeptide NZ_CP044133.1 Lanthipeptides: F3129_RS06725_lanthipeptide NZ_CP044444.1 Lanthipeptides: F7V86_RS13675_lanthipeptide NZ_CP044444.1 Lanthipeptides: F7V86_RS13675_lanthipeptide NZ_CP048002.1 Lanthipeptides: GWK37_RS15585_lanthipeptide NZ_CP048002.1 Lanthipeptides: GWK37_RS15585_lanthipeptide NZ_CP059405.1 Lanthipeptides: H1Q60_RS16390_lanthipeptide NZ_CP059405.1 Lanthipeptides: H1Q60_RS16390_lanthipeptide NZ_CP059495.1 Lanthipeptides: H2N74_RS06615_lanthipeptide NZ_CP059495.1 Lanthipeptides: H2N74_RS06615_lanthipeptide NZ_CP064091.1 Lanthipeptides: IRJ21_RS18885_lanthipeptide NZ_CP064091.1 Lanthipeptides: IRJ21_RS18885_lanthipeptide NZ_CP065790.1 Lanthipeptides: I8N72_RS06390_lanthipeptide NZ_CP065790.1 Lanthipeptides: I8N72_RS06390_lanthipeptide NZ_CP072310.1 Lanthipeptides: J4774_RS16735_lanthipeptide NZ_CP072310.1 Lanthipeptides: J4774_RS16735_lanthipeptide NZ_CP074685.1 Lanthipeptides: KH263_RS06105_lanthipeptide NZ_CP074685.1 Lanthipeptides: KH263_RS06105_lanthipeptide NZ_CP075054.1 Lanthipeptides: KH277_RS12985_lanthipeptide NZ_CP075054.1 Lanthipeptides: KH277_RS12985_lanthipeptide NZ_CP083716.1 Lanthipeptides: LAZ96_RS17615_lanthipeptide NZ_CP083716.1 Lanthipeptides: LAZ96_RS17615_lanthipeptide NZ_CP088300.1 Lanthipeptides: LQ763_RS06060_lanthipeptide NZ_CP088300.1 Lanthipeptides: LQ763_RS06060_lanthipeptide NZ_CP090905.1 Lanthipeptides: L0961_RS06240_lanthipeptide NZ_CP090905.1 Lanthipeptides: L0961_RS06240_lanthipeptide NZ_CP092110.1 Lanthipeptides: LGL65_RS03460_lanthipeptide NZ_CP092110.1 Lanthipeptides: LGL65_RS03460_lanthipeptide NZ_CP094618.1 Lanthipeptides: MTX90_RS05860_lanthipeptide NZ_CP094618.1 Lanthipeptides: MTX90_RS05860_lanthipeptide NZ_CP116013.1 Lanthipeptides: PF986_RS01805_lanthipeptide NZ_CP116013.1 Lanthipeptides: PF986_RS01805_lanthipeptide NZ_CP119675.1 Lanthipeptides: PX690_RS11625_lanthipeptide NZ_CP119675.1 Lanthipeptides: PX690_RS11625_lanthipeptide NZ_JAJNPN010000001.1 Lanthipeptides: LQ568_RS00610_lanthipeptide NZ_JAJNPN010000001.1 Lanthipeptides: LQ568_RS00610_lanthipeptide NZ_JAQEMJ010000002.1 Lanthipeptides: PGW53_RS02950_lanthipeptide NZ_JAQEMJ010000002.1 Lanthipeptides: PGW53_RS02950_lanthipeptide NZ_KB206086.1 Lanthipeptides: A154_RS0102805_lanthipeptide NZ_KB206086.1 Lanthipeptides: A154_RS0102805_lanthipeptide NZ_KN050798.1 Lanthipeptides: BR62_RS0113960_lanthipeptide NZ_KN050798.1 Lanthipeptides: BR62_RS0113960_lanthipeptide NZ_LN999829.1 Lanthipeptides: BAMMD1_RS05930_lanthipeptide NZ_LN999829.1 Lanthipeptides: BAMMD1_RS05930_lanthipeptide NZ_PVRO01000002.1 Lanthipeptides: C6354_RS06030_lanthipeptide NZ_PVRO01000002.1 Lanthipeptides: C6354_RS06030_lanthipeptide
Lanthipeptides: U722_RS06170_lanthipeptide
1
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A E G I S+ N D G K C T L T W E C +C P T H T C W C
7
G A E Q R G I S Q G N D G K L C T L T W E C G L C P T H T C W C
38
60.5%
NZ_JAGGQH010000006.1 and 1 other:
NZ_JAGGQH010000006.1 Lanthipeptides: J7E20_RS10220_lanthipeptide
Lanthipeptides: J7E20_RS10220_lanthipeptide
1
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A E G I S+ N D G K C T L T W E C +C P T H T C+C
7
G A E Q R G I S Q G N D G K L C T L T W E C G L C P T H T C F C
38
50.0%
NZ_CP040417.1 and 7 others:
NZ_CP040417.1 Lanthipeptides: FE328_RS09040_lanthipeptide NZ_CP040419.1 Lanthipeptides: FE326_RS02895_lanthipeptide NZ_CP040419.1 Lanthipeptides: FE326_RS02895_lanthipeptide NZ_CP040421.1 Lanthipeptides: FE324_RS02835_lanthipeptide NZ_CP040421.1 Lanthipeptides: FE324_RS02835_lanthipeptide NZ_CP040422.1 Lanthipeptides: FE323_RS02870_lanthipeptide NZ_CP040422.1 Lanthipeptides: FE323_RS02870_lanthipeptide
Lanthipeptides: FE328_RS09040_lanthipeptide
7
I S E D N D G K Y C T L T W E C S I C P T H T C W
31
+S+ N G K C T L T W E C I C P+H T C+
9
L S K G N T G K V C T L T W E C G I C P S H T C F
33

#### MIBiG 4.0 matches for NP440_RS09135

28.1%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
11
N D G K Y C T L T W E C
22
N G Y C T L T E C
12
N K G A Y C T L T V E C
23
25.0%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
11
N D G K Y C T L T W E C
22
N+G +C T L T E C
14
N N G G W C T L T K E C
25
12.8%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
16
C T L T W E C
22
C T L+ E C
28
C T L S K E C
34
with 1 more sequence matches
12.5%
BGC0000580.3 (EGD17355.1):
Lasso peptide: xanthomonin II or xanthomonin I
5
M G I S E D
10
+G I S+D
15
L G I S Q D
20
NP440_RS09140
Leader:
MEKKVCAYKKISVEDLREVSGG
Core:
A A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N G
Core with dehydrations:
A A E P Q G Dhb P Dhb V Dhb I P I Dha A A I Cys P Dhb Dhb Q Cys A Dha I V R P Cys N N G

#### antiSMASH-DB 4.0 matches for NP440_RS09140

100.0%
NZ_CP101913.1 and 1 other:
NZ_CP101913.1 Lanthipeptides: NP440_RS09140_lanthipeptide
Lanthipeptides: NP440_RS09140_lanthipeptide
1
A A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N G
34
A A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N G
1
A A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N G
34
67.6%
NZ_BOSN01000007.1 and 3 others:
NZ_BOSN01000007.1 Lanthipeptides: KJS43_RS18000_lanthipeptide NZ_JAHHXV010000040.1 Lanthipeptides: KM914_RS20955_lanthipeptide NZ_JAHHXV010000040.1 Lanthipeptides: KM914_RS20955_lanthipeptide
Lanthipeptides: KJS43_RS18000_lanthipeptide
1
A A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N
33
A+E P Q G T P I P+S A I C P T T+C A S+V+P C N
1
A S E P Q G T P A T I I P V S L A I C P T T K C A S V V K P C N G
33
67.6%
NZ_CP063142.1 and 5 others:
NZ_CP063142.1 Lanthipeptides: HPB58_RS21455_lanthipeptide NZ_JALAMS010000001.1 Lanthipeptides: MOC86_RS01475_lanthipeptide NZ_JALAMS010000001.1 Lanthipeptides: MOC86_RS01475_lanthipeptide NZ_LWAI01000057.1 Lanthipeptides: A4U60_RS22255_lanthipeptide NZ_LWAI01000057.1 Lanthipeptides: A4U60_RS22255_lanthipeptide
Lanthipeptides: HPB58_RS21455_lanthipeptide
2
A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N
33
A E + T V T I P I S A C P T T Q C A S I V P C N+
1
A E E R A I W T V T I P I S L A A C P T T Q C A S I V S P C N D
32
with 79 more sequence matches
Only the first 10 are displayed here.
64.7%
NZ_LT745762.1 and 1 other:
NZ_LT745762.1 Lanthipeptides: B2C77_RS21505_lanthipeptide
Lanthipeptides: B2C77_RS21505_lanthipeptide
1
A A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N
33
++E P Q G T P I P+S A I C P T T+C A S+V+P C N+
1
S S E P Q G T P A T I I P V S L A I C P T T K C A S V V K P C N D
33
62.9%
NZ_JAMDLZ010000027.1:
Lanthipeptides: M5W82_RS15520_lanthipeptide
3
E P Q G T P-T V T I P I S A A I C P T T Q C A S I V R P C N N
33
+P+ T P T V T I P I S A C P T T+C A S I V P C
4
Q P K W T P L T V T I P I S L A G C P T T K C A S I V S P C K G
35
61.8%
NZ_KV917378.1 and 1 other:
NZ_KV917378.1 Lanthipeptides: BK581_RS20095_lanthipeptide
Lanthipeptides: BK581_RS20095_lanthipeptide
6
G T P T V T I P I S A A I C P T T Q C A S I V R P C N
32
T T+T I P I S A A C P T T Q C A S+V+P C N
7
A T W T I T I P I S A A A C P T T Q C A S V V K P C N
33
58.8%
NZ_KQ040792.1 and 1 other:
NZ_KQ040792.1 Lanthipeptides: WH45_RS23705_lanthipeptide
Lanthipeptides: WH45_RS23705_lanthipeptide
4
P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N
32
P G T P I P+S A I C P T T+C A S I V C N
5
P N G T P A T I I P V S L A I C P T T R C A S I V E S C N
33
52.9%
NZ_BQME02000001.1 and 3 others:
NZ_BQME02000001.1 Lanthipeptides: MFF31_RS04080_lanthipeptide NZ_BQME02000001.1 Lanthipeptides: MFF31_RS04090_lanthipeptide NZ_BQME02000001.1 Lanthipeptides: MFF31_RS04090_lanthipeptide
Lanthipeptides: MFF31_RS04080_lanthipeptide
9
T V T I P I S A A I C P T T Q C A S I V R P C N
32
T+ I P I S A C P T T+C A S I V P C N
6
T I I I P I S L A A C P T T R C A S I V S P C N
29
52.6%
NZ_AUCI01000015.1 and 1 other:
NZ_AUCI01000015.1 Lanthipeptides: G475_RS0114655_lanthipeptide
Lanthipeptides: G475_RS0114655_lanthipeptide
7
T P T V T I P I S A A I C P T T Q C A S I V R P C N N
33
T T V T I P I S A C P T T+C A S+V P C N+
12
T T T V T I P I S A W G C P T T K C A S V V E P C N D
38
52.6%
NZ_FOXD01000022.1 and 1 other:
NZ_FOXD01000022.1 Lanthipeptides: BM124_RS15255_lanthipeptide
Lanthipeptides: BM124_RS15255_lanthipeptide
7
T P T V T I P I S A A I C P T T Q C A S I V R P C N N
33
T T V T I P I S A C P T T+C A S+V+P C N+
12
T T T V T I P I S A W G C P T T K C A S V V K P C N D
38
50.0%
NZ_BQME02000001.1 and 1 other:
NZ_BQME02000001.1 Lanthipeptides: MFF31_RS04085_lanthipeptide
Lanthipeptides: MFF31_RS04085_lanthipeptide
9
T V T I P I S A A I C P T T Q C A S I V R P C N
32
T+ I P I S A C P T T+C A S I V C N
6
T I I I P I S L A A C P T T R C A S I V S S C N
29
50.0%
NZ_CP040417.1 and 7 others:
NZ_CP040417.1 Lanthipeptides: FE328_RS09035_lanthipeptide NZ_CP040419.1 Lanthipeptides: FE326_RS02890_lanthipeptide NZ_CP040419.1 Lanthipeptides: FE326_RS02890_lanthipeptide NZ_CP040421.1 Lanthipeptides: FE324_RS02830_lanthipeptide NZ_CP040421.1 Lanthipeptides: FE324_RS02830_lanthipeptide NZ_CP040422.1 Lanthipeptides: FE323_RS02865_lanthipeptide NZ_CP040422.1 Lanthipeptides: FE323_RS02865_lanthipeptide
Lanthipeptides: FE328_RS09035_lanthipeptide
9
T V T I P I S A A I C P T T Q C A S I V R P C N N
33
T +P I S A I C P+T+C A S I R P C N
4
T S L V P I S L A I C P S T K C A S I T R P C N K
28
50.0%
NZ_WIXN01000006.1 and 1 other:
NZ_WIXN01000006.1 Lanthipeptides: GHD25_RS06900_lanthipeptide
Lanthipeptides: GHD25_RS06900_lanthipeptide
2
A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N
33
A P P T I P+S A+C P T T C S P C N
3
A T P D T H P T T I I P V S L A V C P T T T C R S F S S P C P N
34

#### MIBiG 4.0 matches for NP440_RS09140

27.0%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
10
V T I P I S A A I C P T T Q C A S
26
V + +S A A C P T T+C S
19
V A V G V S A A F C P T T K C T S
35
17.6%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
18
I C P T T Q C A S
26
C P T T+C S
16
F C P T T K C T S
24
allorf_1817119_1817316
Leader:
MPTSSRSPLMGDGVPFVEWTGELRSYARLSGRHGA
Core:
V A K A S L N R A N E Y A V V D P K L C D L P M S R V K V R
Core with dehydrations:
V A K A Dha L N R A N E Y A V V D P K L Cys D L P M Dha R V K V R

#### antiSMASH-DB 4.0 matches for allorf_1817119_1817316

100.0%
NZ_CP101913.1:
Lanthipeptides: allorf_1817119_1817316_lanthipeptide
1
V A K A S L N R A N E Y A V V D P K L C D L P M S R V K V R
30
V A K A S L N R A N E Y A V V D P K L C D L P M S R V K V R
1
V A K A S L N R A N E Y A V V D P K L C D L P M S R V K V R
30
86.7%
NZ_AP026714.1 and 3 others:
NZ_KZ845958.1 Lanthipeptides: allorf_1543494_1543619_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_000497_000622_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1658436_1658561_lanthipeptide
Lanthipeptides: allorf_1208773_1208898_lanthipeptide
2
A K A S L N R A N E Y A V V D P K L C D L P M S R V K V R
30
A K A S L N R A N E Y V V D P K C D L P M S R+K V R
2
A K A S L N R A N E Y V V V D P K P C D L P M S R L K V R
30
21.1%
NZ_JANVAG010000003.1:
Lanthipeptides: allorf_436904_437122_lanthipeptide
11
E Y A V V D P K L C D L P M S R V
27
E A+ D P C D P + V
7
E S A I T D P S G C D-P T T T V
22
with 1 more sequence matches
12.2%
NZ_QJTF01000024.1:
Lanthipeptides: allorf_43991_44197_lanthipeptide
14
V V D P K L C D L P M S
25
++ P K+C D S
17
M I T P K V C D F S E S
28

#### MIBiG 4.0 matches for allorf_1817119_1817316

13.3%
BGC0000553.3 (SSGG_RS09925):
Lanthipeptide: SRO15-2212
11
E Y A V V D P K L C D
21
E Y+ + L C
11
E Y S S L S V V L C T
21
allorf_1818003_1818074
Leader:
MLGRTSIGA
Core:
H S L S S C V P P L L K Q S
Core with dehydrations:
H Dha L Dha Dha Cys V P P L L K Q Dha

#### antiSMASH-DB 4.0 matches for allorf_1818003_1818074

100.0%
NZ_CP101913.1:
Lanthipeptides: allorf_1818003_1818074_lanthipeptide
1
H S L S S C V P P L L K Q S
14
H S L S S C V P P L L K Q S
1
H S L S S C V P P L L K Q S
14
allorf_1818328_1818426
Leader:
MNRPKRLFSKNTGLCEAERRSIGA
Core:
D T C P V L E G
Core with dehydrations:
D Dhb Cys P V L E G

#### antiSMASH-DB 4.0 matches for allorf_1818328_1818426

100.0%
NZ_CM000721.1 and 1 other:
NZ_CP101913.1 Lanthipeptides: allorf_1818328_1818426_lanthipeptide
Lanthipeptides: allorf_5215482_5215580_lanthipeptide
1
D T C P V L E G
8
D T C P V L E G
1
D T C P V L E G
8
allorf_1818804_1818965
Leader:
MSGGQFDWGGRLLKGNGG
Core:
A Q R F P Q N G W K S F E E C K G R R E L D C E T Y K S S R D E S R A
Core with dehydrations:
A Q R F P Q N G W K Dha F E E Cys K G R R E L D Cys E Dhb Y K Dha Dha R D E Dha R A

#### antiSMASH-DB 4.0 matches for allorf_1818804_1818965

100.0%
NZ_AP026714.1 and 4 others:
NZ_CP101913.1 Lanthipeptides: allorf_1818804_1818965_lanthipeptide NZ_KZ845958.1 Lanthipeptides: allorf_1541847_1542008_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_002108_002269_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1656789_1656950_lanthipeptide
Lanthipeptides: allorf_1210384_1210545_lanthipeptide
1
A Q R F P Q N G W K S F E E C K G R R E L D C E T Y K S S R D E S R A
35
A Q R F P Q N G W K S F E E C K G R R E L D C E T Y K S S R D E S R A
1
A Q R F P Q N G W K S F E E C K G R R E L D C E T Y K S S R D E S R A
35
94.3%
NZ_CM000721.1:
Lanthipeptides: allorf_5214947_5215108_lanthipeptide
1
A Q R F P Q N G W K S F E E C K G R R E L D C E T Y K S S R D E S R A
35
A Q R F P Q N G W K S F E C K G R E L D C E T Y K S S R D E S R A
1
A Q R F P Q N G W K S F V E C K G I R E L D C E T Y K S S R D E S R A
35
94.3%
NZ_CP039297.1 and 3 others:
NZ_CP040672.1 Lanthipeptides: allorf_1096094_1096255_lanthipeptide NZ_CP059318.1 Lanthipeptides: allorf_0101095_0101256_lanthipeptide NZ_CP087137.1 Lanthipeptides: allorf_0100933_0101094_lanthipeptide
Lanthipeptides: allorf_0101160_0101321_lanthipeptide
1
A Q R F P Q N G W K S F E E C K G R R E L D C E T Y K S S R D E S R A
35
A Q R F P Q N G W K S F E C K G R E L D C E T Y K S S R D E S R A
1
A Q R F P Q N G W K S F A E C K G T R E L D C E T Y K S S R D E S R A
35
with 1 more sequence matches
88.6%
NC_015215.1:
Lanthipeptides: allorf_0087347_0087508_lanthipeptide
1
A Q R F P Q N G W K S F E E C K G R R E L D C E T Y K S S R D E S R A
35
A Q R F P Q N G W K S F E C K G R E L D C E+Y S S R D E S R A
1
A Q R F P Q N G W K S F A E C K G I R E L D C E S Y N S S R D E S R A
35
allorf_1819068_1819298
Leader:
MAPRCRLIASWGCSRSQGLGCSPIKAVRELGS
Core:
E R R E T V R S L S V V G V G S L R G A V L S T R G P G W T H R W C T S C S A R S I A G
Core with dehydrations:
E R R E Dhb V R Dha L Dha V V G V G Dha L R G A V L Dha Dhb R G P G W Dhb H R W Cys Dhb Dha Cys Dha A R Dha I A G

#### antiSMASH-DB 4.0 matches for allorf_1819068_1819298

100.0%
NZ_CP101913.1:
Lanthipeptides: allorf_1819068_1819298_lanthipeptide
1
E R R E T V R S L S V V G V G S L R G A V L S T R G P G W T H R W C T S C S A R S I A G
44
E R R E T V R S L S V V G V G S L R G A V L S T R G P G W T H R W C T S C S A R S I A G
1
E R R E T V R S L S V V G V G S L R G A V L S T R G P G W T H R W C T S C S A R S I A G
44
77.3%
NC_015215.1:
Lanthipeptides: allorf_0087611_0087841_lanthipeptide
1
E R R E T V R S L S V V G V G S L R G A V L S T R G P G W T H R W C T S C S A R S I A G
44
E R R E T V R S L S V G V G+L R G+ S T R G P W T+R W C T S C A+ I A G
1
E R R E T V R S L S V A G V G N L R G S A P S T R G P E W T Y R W C T S C L A K G I A G
44
61.4%
NZ_CP039297.1 and 3 others:
NZ_CP040672.1 Lanthipeptides: allorf_1096358_1096588_lanthipeptide NZ_CP059318.1 Lanthipeptides: allorf_0101359_0101589_lanthipeptide NZ_CP087137.1 Lanthipeptides: allorf_0101197_0101427_lanthipeptide
Lanthipeptides: allorf_0101424_0101654_lanthipeptide
15
G S L R G A V L S T R G P G W T H R W C T S C S A R S I A G
44
G+L R G A V L S T R G P G W T H R W C T S C S A+ I A G
1
G N L R G A V L S T R G P G W T H R W C T S C S A K G I A G
30
with 5 more sequence matches
50.0%
NZ_CM000721.1:
Lanthipeptides: allorf_5214614_5214844_lanthipeptide
21
V L S T R G P G W T H R W C T S C S A R S I A G
44
V L S T R G P G W T H R W C T S C S A+ I A G
1
V L S T R G P G W T H R W C T S C S A K G I A G
24
47.7%
NZ_AP026714.1 and 4 others:
NZ_KZ845958.1 Lanthipeptides: allorf_1541514_1541744_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_002372_002602_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_002372_002602_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1656456_1656686_lanthipeptide
Lanthipeptides: allorf_1210648_1210878_lanthipeptide
21
V L S T R G P G W T H R W C T S C S A R S I A G
44
V L S T R G P G W T+R W C T S C S A+ I A G
1
V L S T R G P G W T Y R W C T S C S A K G I A G
24
18.2%
NZ_CP025546.1 and 5 others:
NZ_CP025546.1 Lanthipeptides: allorf_4260056_4260220_lanthipeptide NZ_SDLM01000003.1 Lanthipeptides: allorf_121827_121991_lanthipeptide NZ_SDLM01000003.1 Lanthipeptides: allorf_121827_121991_lanthipeptide NZ_SDLN01000007.1 Lanthipeptides: allorf_135103_135267_lanthipeptide NZ_SDLN01000007.1 Lanthipeptides: allorf_135103_135267_lanthipeptide
Lanthipeptides: allorf_4260056_4260220_lanthipeptide
23
S T R G P G W T H R W C T S C S
38
+ R G P W W T C S
3
T K R G P T W D P L W A T P C S
18
18.2%
NZ_JANIOB010000033.1:
Lanthipeptides: NQ113_RS28010_lanthipeptide
15
G S L R G A V L S T R G P G W T H R W C T S--C S A R
40
G + P G+T+R C + C+ R
1
G D V N P E T T P V I N P G F T N R L C P T I P C T L R
28
11.4%
NZ_CP041611.1 and 1 other:
NZ_CP041613.2 Lanthipeptides: allorf_01201490_01201714_lanthipeptide
Lanthipeptides: allorf_00809662_00809886_lanthipeptide
26
G P G W T H
31
G P G W+H
9
G P G W S H
14

#### MIBiG 4.0 matches for allorf_1819068_1819298

9.1%
BGC0001155.5 (AGY49587.1):
Thiopeptide: GE2270
33
W C T S C S
38
+C S C S
8
F C C S C S
13
allorf_1820059_1820208
Leader:
MNLRPLGYEPNELPDCSTPRYEFMNLHGG
Core:
G C R A R T C D P L L V R Q V L S Q L S
Core with dehydrations:
G Cys R A R Dhb Cys D P L L V R Q V L Dha Q L Dha

#### antiSMASH-DB 4.0 matches for allorf_1820059_1820208

100.0%
NZ_CP101913.1:
Lanthipeptides: allorf_1820059_1820208_lanthipeptide
1
G C R A R T C D P L L V R Q V L S Q L S
20
G C R A R T C D P L L V R Q V L S Q L S
1
G C R A R T C D P L L V R Q V L S Q L S
20
33.3%
NZ_LMHX01000004.1:
Lanthipeptides: allorf_642221_642325_lanthipeptide
8
D P L L V R Q V L S Q
18
D P + R Q L S Q
11
D P Y V D R Q A L S Q
21
30.0%
NZ_KQ061217.1:
Lanthipeptides: allorf_2991306_2991515_lanthipeptide
3
R A R T C D P L L V R Q V
15
R A+ C D P + Q
3
R A K C C D P K V T T Q A
15
with 4 more sequence matches
27.3%
NZ_CP095076.1:
Lassopeptides: MUO15_RS21105_lassopeptide
2
C R A R T C D P L L V R Q
14
C +C D L V R
10
C Y D N S C D F Y L V R N
22
17.1%
NZ_JAQDDK010000012.1 and 2 others:
NZ_LT969517.1 Lanthipeptides: allorf_3004413_3004634_lanthipeptide NZ_QVLV01000012.1 Lanthipeptides: allorf_057847_058068_lanthipeptide
Lanthipeptides: allorf_057187_057408_lanthipeptide
3
R A R T C D P L L V R Q
14
R R C P+L+ Q
21
R N R A C T P V L L S Q
32
14.3%
NZ_KB895870.1 and 1 other:
NZ_KB895870.1 Lanthipeptides: C569_RS0127950_lanthipeptide
Lanthipeptides: C569_RS0127950_lanthipeptide
2
C R A R T C D P L
10
C ++C D P+
20
C T T K S C D P V
28
10.0%
NZ_CP011129.1:
Lanthipeptides: allorf_3545419_3545634_lanthipeptide
5
R T C D P L L V R Q V L
16
R+C P L+ R+
25
R S C G P L I Q R K A F
36
allorf_1820488_1820661
Leader:
MGIEPTCAGA
Core:
T I R C V N H F A T T A I L A G V V G I E P T S K V L E T F V L P L N Y T P M I F Y K W W R E
Core with dehydrations:
Dhb I R Cys V N H F A Dhb Dhb A I L A G V V G I E P Dhb Dha K V L E Dhb F V L P L N Y Dhb P M I F Y K W W R E

#### antiSMASH-DB 4.0 matches for allorf_1820488_1820661

100.0%
NZ_CP101913.1 and 1 other:
NZ_CP101913.1 Lanthipeptides: allorf_1820488_1820661_lanthipeptide
Lanthipeptides: allorf_1820488_1820661_lanthipeptide
1
T I R C V N H F A T T A I L A G V V G I E P T S K V L E T F V L P L N Y T P M I F Y K W W R E
47
T I R C V N H F A T T A I L A G V V G I E P T S K V L E T F V L P L N Y T P M I F Y K W W R E
1
T I R C V N H F A T T A I L A G V V G I E P T S K V L E T F V L P L N Y T P M I F Y K W W R E
47
17.0%
NZ_NGNA01000004.1:
Lanthipeptides: A5881_RS20710_lanthipeptide
15
A G V V G I E P T S K V L E T F V L P L N Y T P M I F Y K
43
G V V ++ +P++Y T + Y K
4
Q G T V S N I E N K N V C D S L E I P V S Y T H L D V Y K
32
12.8%
NZ_BDUD01000001.1 and 1 other:
NZ_BDUD01000001.1 Lanthipeptides: allorf_2999243_2999452_lanthipeptide
Lanthipeptides: allorf_2999243_2999452_lanthipeptide
2
I R C V N H F A T T A I L A G V
17
+R C+N+F T I +
18
L R C L N Y F V E T R I F T S L
33

#### MIBiG 4.0 matches for allorf_1820488_1820661

8.5%
BGC0000581.6 (AAD28494.1):
Lasso peptide: microcin J25
37
T P M I F Y K
43
T P+ F Y
15
T P I S F Y G
21
allorf_1821134_1821229
Leader:
MIILNRMTGS
Core:
T A G L L P L E E T A T K K Q P K I R V C
Core with dehydrations:
Dhb A G L L P L E E Dhb A Dhb K K Q P K I R V Cys

#### antiSMASH-DB 4.0 matches for allorf_1821134_1821229

100.0%
NZ_CP101913.1 and 1 other:
NZ_CP101913.1 Lanthipeptides: allorf_1821134_1821229_lanthipeptide
Lanthipeptides: allorf_1821134_1821229_lanthipeptide
1
T A G L L P L E E T A T K K Q P K I R V C
21
T A G L L P L E E T A T K K Q P K I R V C
1
T A G L L P L E E T A T K K Q P K I R V C
21

#### Lanthipeptide(s) for NP440_RS09145

NP440_RS09135
Leader:
MKEKDLQLFNTAGDFMSELEEASLKNISGG
Core:
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
Core with dehydrations:
A A E P M G I Dha E D N D G K Y Cys Dhb L Dhb W E Cys Dha I Cys P Dhb H Dhb Cys W Cys

#### antiSMASH-DB 4.0 matches for NP440_RS09135

100.0%
NZ_CP101913.1 and 1 other:
NZ_CP101913.1 Lanthipeptides: NP440_RS09135_lanthipeptide
Lanthipeptides: NP440_RS09135_lanthipeptide
1
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
1
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
90.6%
NZ_BOSN01000007.1 and 3 others:
NZ_BOSN01000007.1 Lanthipeptides: KJS43_RS18005_lanthipeptide NZ_JAHHXV010000040.1 Lanthipeptides: KM914_RS20960_lanthipeptide NZ_JAHHXV010000040.1 Lanthipeptides: KM914_RS20960_lanthipeptide
Lanthipeptides: KJS43_RS18005_lanthipeptide
1
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A A E P M G I S+ N D G K Y C T+T W E C S I C P T H T C W C
1
A A E P M G I S Q G N D G K Y C T I T W E C S I C P T H T C W C
32
87.5%
NZ_LT745762.1 and 1 other:
NZ_LT745762.1 Lanthipeptides: B2C77_RS00795_lanthipeptide
Lanthipeptides: B2C77_RS00795_lanthipeptide
1
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A A E P M G I S+ N D G K+C T+T W E C S I C P T H T C W C
1
A A E P M G I S Q G N D G K W C T V T W E C S I C P T H T C W C
32
with 100 more sequence matches
Only the first 10 are displayed here.
78.1%
NZ_BQME02000001.1 and 1 other:
NZ_BQME02000001.1 Lanthipeptides: MFF31_RS04105_lanthipeptide
Lanthipeptides: MFF31_RS04105_lanthipeptide
2
A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C-W C
32
A E G I S+ N D G K Y C T L T W E C S+C P T T C W C
1
A E Q R G I S Q G N D G K Y C T L T W E C S V C P T L T C F W C
32
78.1%
NZ_KV917378.1 and 1 other:
NZ_KV917378.1 Lanthipeptides: BK581_RS07320_lanthipeptide
Lanthipeptides: BK581_RS07320_lanthipeptide
2
A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A+ G I S+ N D G K Y C T+T W E C S I C P T H T C W C
1
A D V Q G I S Q G N D G K Y C T I T W E C S I C P T H T C W C
31
75.0%
NZ_CP063142.1 and 10 others:
NZ_CP063142.1 Lanthipeptides: HPB58_RS21475_lanthipeptide NZ_FOXX01000007.1 Lanthipeptides: BM012_RS26100_lanthipeptide NZ_JALAMS010000001.1 Lanthipeptides: MOC86_RS01460_lanthipeptide NZ_JALAMS010000001.1 Lanthipeptides: MOC86_RS01460_lanthipeptide NZ_LVYL01000023.1 Lanthipeptides: A3863_RS12035_lanthipeptide NZ_LVYL01000023.1 Lanthipeptides: A3863_RS12035_lanthipeptide NZ_LWAG01000015.1 Lanthipeptides: A4R27_RS06450_lanthipeptide NZ_LWAG01000015.1 Lanthipeptides: A4R27_RS06450_lanthipeptide NZ_LWAI01000057.1 Lanthipeptides: A4U60_RS22240_lanthipeptide NZ_LWAI01000057.1 Lanthipeptides: A4U60_RS22240_lanthipeptide
Lanthipeptides: HPB58_RS21475_lanthipeptide
2
A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A E G I S+ N D G C T+T W E C S I C P T H T C W C
1
A E Q R G I S Q G N D G H Q C T I T W E C S I C P T H T C W C
31
72.7%
NZ_FOXD01000022.1 and 1 other:
NZ_FOXD01000022.1 Lanthipeptides: BM124_RS15270_lanthipeptide
Lanthipeptides: BM124_RS15270_lanthipeptide
2
A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A E P G I S+ N D G Y C T+T W E C +C P T H T C W C
3
A E P R G I S Q G N D G D Y C T I T W E C G M C P T H T C W C
33
68.8%
NZ_JAMDLZ010000027.1:
Lanthipeptides: M5W82_RS15515_lanthipeptide
2
A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W
31
E I S+ N D G K+C T L T W E C S I C P T T C W
1
V E T K K I S K G N D G K W C T L T W E C S I C P T K T C W
30
68.8%
NZ_KQ040792.1 and 1 other:
NZ_KQ040792.1 Lanthipeptides: WH45_RS23330_lanthipeptide
Lanthipeptides: WH45_RS23330_lanthipeptide
2
A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A E G+S+ N D G K C T L T W E C +C P T H T C+C
1
A E V Q G L S Q G N D G K V C T L T W E C G L C P T H T C F C
31
63.6%
NZ_AUCI01000015.1 and 1 other:
NZ_AUCI01000015.1 Lanthipeptides: G475_RS0114640_lanthipeptide
Lanthipeptides: G475_RS0114640_lanthipeptide
2
A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
E G+S+ N D G Y C T+T W E C +C P T H T C W C
3
V E T R G L S Q G N D G D Y C T I T W E C G M C P T H T C W C
33
63.2%
NC_023073.1 and 73 others:
NC_023073.1 Lanthipeptides: U722_RS06170_lanthipeptide NZ_CP010556.1 Lanthipeptides: SB45_RS05930_lanthipeptide NZ_CP010556.1 Lanthipeptides: SB45_RS05930_lanthipeptide NZ_CP016371.1 Lanthipeptides: A5891_RS06120_lanthipeptide NZ_CP016371.1 Lanthipeptides: A5891_RS06120_lanthipeptide NZ_CP016395.1 Lanthipeptides: BBJ33_RS06540_lanthipeptide NZ_CP016395.1 Lanthipeptides: BBJ33_RS06540_lanthipeptide NZ_CP017775.1 Lanthipeptides: BK055_RS07100_lanthipeptide NZ_CP017775.1 Lanthipeptides: BK055_RS07100_lanthipeptide NZ_CP018295.1 Lanthipeptides: BHE96_RS06300_lanthipeptide NZ_CP018295.1 Lanthipeptides: BHE96_RS06300_lanthipeptide NZ_CP023075.1 Lanthipeptides: CK238_RS06735_lanthipeptide NZ_CP023075.1 Lanthipeptides: CK238_RS06735_lanthipeptide NZ_CP023133.1 Lanthipeptides: CJP14_RS04225_lanthipeptide NZ_CP023133.1 Lanthipeptides: CJP14_RS04225_lanthipeptide NZ_CP025341.1 Lanthipeptides: CXR48_RS06135_lanthipeptide NZ_CP025341.1 Lanthipeptides: CXR48_RS06135_lanthipeptide NZ_CP027429.1 Lanthipeptides: C6P48_RS12845_lanthipeptide NZ_CP027429.1 Lanthipeptides: C6P48_RS12845_lanthipeptide NZ_CP028440.1 Lanthipeptides: DA378_RS05125_lanthipeptide NZ_CP028440.1 Lanthipeptides: DA378_RS05125_lanthipeptide NZ_CP031694.1 Lanthipeptides: DXY21_RS18530_lanthipeptide NZ_CP031694.1 Lanthipeptides: DXY21_RS18530_lanthipeptide NZ_CP033967.1 Lanthipeptides: EG882_RS17885_lanthipeptide NZ_CP033967.1 Lanthipeptides: EG882_RS17885_lanthipeptide NZ_CP035393.1 Lanthipeptides: ES966_RS07170_lanthipeptide NZ_CP035393.1 Lanthipeptides: ES966_RS07170_lanthipeptide NZ_CP044133.1 Lanthipeptides: F3129_RS06725_lanthipeptide NZ_CP044133.1 Lanthipeptides: F3129_RS06725_lanthipeptide NZ_CP044444.1 Lanthipeptides: F7V86_RS13675_lanthipeptide NZ_CP044444.1 Lanthipeptides: F7V86_RS13675_lanthipeptide NZ_CP048002.1 Lanthipeptides: GWK37_RS15585_lanthipeptide NZ_CP048002.1 Lanthipeptides: GWK37_RS15585_lanthipeptide NZ_CP059405.1 Lanthipeptides: H1Q60_RS16390_lanthipeptide NZ_CP059405.1 Lanthipeptides: H1Q60_RS16390_lanthipeptide NZ_CP059495.1 Lanthipeptides: H2N74_RS06615_lanthipeptide NZ_CP059495.1 Lanthipeptides: H2N74_RS06615_lanthipeptide NZ_CP064091.1 Lanthipeptides: IRJ21_RS18885_lanthipeptide NZ_CP064091.1 Lanthipeptides: IRJ21_RS18885_lanthipeptide NZ_CP065790.1 Lanthipeptides: I8N72_RS06390_lanthipeptide NZ_CP065790.1 Lanthipeptides: I8N72_RS06390_lanthipeptide NZ_CP072310.1 Lanthipeptides: J4774_RS16735_lanthipeptide NZ_CP072310.1 Lanthipeptides: J4774_RS16735_lanthipeptide NZ_CP074685.1 Lanthipeptides: KH263_RS06105_lanthipeptide NZ_CP074685.1 Lanthipeptides: KH263_RS06105_lanthipeptide NZ_CP075054.1 Lanthipeptides: KH277_RS12985_lanthipeptide NZ_CP075054.1 Lanthipeptides: KH277_RS12985_lanthipeptide NZ_CP083716.1 Lanthipeptides: LAZ96_RS17615_lanthipeptide NZ_CP083716.1 Lanthipeptides: LAZ96_RS17615_lanthipeptide NZ_CP088300.1 Lanthipeptides: LQ763_RS06060_lanthipeptide NZ_CP088300.1 Lanthipeptides: LQ763_RS06060_lanthipeptide NZ_CP090905.1 Lanthipeptides: L0961_RS06240_lanthipeptide NZ_CP090905.1 Lanthipeptides: L0961_RS06240_lanthipeptide NZ_CP092110.1 Lanthipeptides: LGL65_RS03460_lanthipeptide NZ_CP092110.1 Lanthipeptides: LGL65_RS03460_lanthipeptide NZ_CP094618.1 Lanthipeptides: MTX90_RS05860_lanthipeptide NZ_CP094618.1 Lanthipeptides: MTX90_RS05860_lanthipeptide NZ_CP116013.1 Lanthipeptides: PF986_RS01805_lanthipeptide NZ_CP116013.1 Lanthipeptides: PF986_RS01805_lanthipeptide NZ_CP119675.1 Lanthipeptides: PX690_RS11625_lanthipeptide NZ_CP119675.1 Lanthipeptides: PX690_RS11625_lanthipeptide NZ_JAJNPN010000001.1 Lanthipeptides: LQ568_RS00610_lanthipeptide NZ_JAJNPN010000001.1 Lanthipeptides: LQ568_RS00610_lanthipeptide NZ_JAQEMJ010000002.1 Lanthipeptides: PGW53_RS02950_lanthipeptide NZ_JAQEMJ010000002.1 Lanthipeptides: PGW53_RS02950_lanthipeptide NZ_KB206086.1 Lanthipeptides: A154_RS0102805_lanthipeptide NZ_KB206086.1 Lanthipeptides: A154_RS0102805_lanthipeptide NZ_KN050798.1 Lanthipeptides: BR62_RS0113960_lanthipeptide NZ_KN050798.1 Lanthipeptides: BR62_RS0113960_lanthipeptide NZ_LN999829.1 Lanthipeptides: BAMMD1_RS05930_lanthipeptide NZ_LN999829.1 Lanthipeptides: BAMMD1_RS05930_lanthipeptide NZ_PVRO01000002.1 Lanthipeptides: C6354_RS06030_lanthipeptide NZ_PVRO01000002.1 Lanthipeptides: C6354_RS06030_lanthipeptide
Lanthipeptides: U722_RS06170_lanthipeptide
1
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A E G I S+ N D G K C T L T W E C +C P T H T C W C
7
G A E Q R G I S Q G N D G K L C T L T W E C G L C P T H T C W C
38
60.5%
NZ_JAGGQH010000006.1 and 1 other:
NZ_JAGGQH010000006.1 Lanthipeptides: J7E20_RS10220_lanthipeptide
Lanthipeptides: J7E20_RS10220_lanthipeptide
1
A A E P M G I S E D N D G K Y C T L T W E C S I C P T H T C W C
32
A E G I S+ N D G K C T L T W E C +C P T H T C+C
7
G A E Q R G I S Q G N D G K L C T L T W E C G L C P T H T C F C
38
50.0%
NZ_CP040417.1 and 7 others:
NZ_CP040417.1 Lanthipeptides: FE328_RS09040_lanthipeptide NZ_CP040419.1 Lanthipeptides: FE326_RS02895_lanthipeptide NZ_CP040419.1 Lanthipeptides: FE326_RS02895_lanthipeptide NZ_CP040421.1 Lanthipeptides: FE324_RS02835_lanthipeptide NZ_CP040421.1 Lanthipeptides: FE324_RS02835_lanthipeptide NZ_CP040422.1 Lanthipeptides: FE323_RS02870_lanthipeptide NZ_CP040422.1 Lanthipeptides: FE323_RS02870_lanthipeptide
Lanthipeptides: FE328_RS09040_lanthipeptide
7
I S E D N D G K Y C T L T W E C S I C P T H T C W
31
+S+ N G K C T L T W E C I C P+H T C+
9
L S K G N T G K V C T L T W E C G I C P S H T C F
33

#### MIBiG 4.0 matches for NP440_RS09135

28.1%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
11
N D G K Y C T L T W E C
22
N G Y C T L T E C
12
N K G A Y C T L T V E C
23
25.0%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
11
N D G K Y C T L T W E C
22
N+G +C T L T E C
14
N N G G W C T L T K E C
25
12.8%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
16
C T L T W E C
22
C T L+ E C
28
C T L S K E C
34
with 1 more sequence matches
12.5%
BGC0000580.3 (EGD17355.1):
Lasso peptide: xanthomonin II or xanthomonin I
5
M G I S E D
10
+G I S+D
15
L G I S Q D
20
NP440_RS09140
Leader:
MEKKVCAYKKISVEDLREVSGG
Core:
A A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N G
Core with dehydrations:
A A E P Q G Dhb P Dhb V Dhb I P I Dha A A I Cys P Dhb Dhb Q Cys A Dha I V R P Cys N N G

#### antiSMASH-DB 4.0 matches for NP440_RS09140

100.0%
NZ_CP101913.1 and 1 other:
NZ_CP101913.1 Lanthipeptides: NP440_RS09140_lanthipeptide
Lanthipeptides: NP440_RS09140_lanthipeptide
1
A A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N G
34
A A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N G
1
A A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N G
34
67.6%
NZ_BOSN01000007.1 and 3 others:
NZ_BOSN01000007.1 Lanthipeptides: KJS43_RS18000_lanthipeptide NZ_JAHHXV010000040.1 Lanthipeptides: KM914_RS20955_lanthipeptide NZ_JAHHXV010000040.1 Lanthipeptides: KM914_RS20955_lanthipeptide
Lanthipeptides: KJS43_RS18000_lanthipeptide
1
A A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N
33
A+E P Q G T P I P+S A I C P T T+C A S+V+P C N
1
A S E P Q G T P A T I I P V S L A I C P T T K C A S V V K P C N G
33
67.6%
NZ_CP063142.1 and 5 others:
NZ_CP063142.1 Lanthipeptides: HPB58_RS21455_lanthipeptide NZ_JALAMS010000001.1 Lanthipeptides: MOC86_RS01475_lanthipeptide NZ_JALAMS010000001.1 Lanthipeptides: MOC86_RS01475_lanthipeptide NZ_LWAI01000057.1 Lanthipeptides: A4U60_RS22255_lanthipeptide NZ_LWAI01000057.1 Lanthipeptides: A4U60_RS22255_lanthipeptide
Lanthipeptides: HPB58_RS21455_lanthipeptide
2
A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N
33
A E + T V T I P I S A C P T T Q C A S I V P C N+
1
A E E R A I W T V T I P I S L A A C P T T Q C A S I V S P C N D
32
with 79 more sequence matches
Only the first 10 are displayed here.
64.7%
NZ_LT745762.1 and 1 other:
NZ_LT745762.1 Lanthipeptides: B2C77_RS21505_lanthipeptide
Lanthipeptides: B2C77_RS21505_lanthipeptide
1
A A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N
33
++E P Q G T P I P+S A I C P T T+C A S+V+P C N+
1
S S E P Q G T P A T I I P V S L A I C P T T K C A S V V K P C N D
33
62.9%
NZ_JAMDLZ010000027.1:
Lanthipeptides: M5W82_RS15520_lanthipeptide
3
E P Q G T P-T V T I P I S A A I C P T T Q C A S I V R P C N N
33
+P+ T P T V T I P I S A C P T T+C A S I V P C
4
Q P K W T P L T V T I P I S L A G C P T T K C A S I V S P C K G
35
61.8%
NZ_KV917378.1 and 1 other:
NZ_KV917378.1 Lanthipeptides: BK581_RS20095_lanthipeptide
Lanthipeptides: BK581_RS20095_lanthipeptide
6
G T P T V T I P I S A A I C P T T Q C A S I V R P C N
32
T T+T I P I S A A C P T T Q C A S+V+P C N
7
A T W T I T I P I S A A A C P T T Q C A S V V K P C N
33
58.8%
NZ_KQ040792.1 and 1 other:
NZ_KQ040792.1 Lanthipeptides: WH45_RS23705_lanthipeptide
Lanthipeptides: WH45_RS23705_lanthipeptide
4
P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N
32
P G T P I P+S A I C P T T+C A S I V C N
5
P N G T P A T I I P V S L A I C P T T R C A S I V E S C N
33
52.9%
NZ_BQME02000001.1 and 3 others:
NZ_BQME02000001.1 Lanthipeptides: MFF31_RS04080_lanthipeptide NZ_BQME02000001.1 Lanthipeptides: MFF31_RS04090_lanthipeptide NZ_BQME02000001.1 Lanthipeptides: MFF31_RS04090_lanthipeptide
Lanthipeptides: MFF31_RS04080_lanthipeptide
9
T V T I P I S A A I C P T T Q C A S I V R P C N
32
T+ I P I S A C P T T+C A S I V P C N
6
T I I I P I S L A A C P T T R C A S I V S P C N
29
52.6%
NZ_AUCI01000015.1 and 1 other:
NZ_AUCI01000015.1 Lanthipeptides: G475_RS0114655_lanthipeptide
Lanthipeptides: G475_RS0114655_lanthipeptide
7
T P T V T I P I S A A I C P T T Q C A S I V R P C N N
33
T T V T I P I S A C P T T+C A S+V P C N+
12
T T T V T I P I S A W G C P T T K C A S V V E P C N D
38
52.6%
NZ_FOXD01000022.1 and 1 other:
NZ_FOXD01000022.1 Lanthipeptides: BM124_RS15255_lanthipeptide
Lanthipeptides: BM124_RS15255_lanthipeptide
7
T P T V T I P I S A A I C P T T Q C A S I V R P C N N
33
T T V T I P I S A C P T T+C A S+V+P C N+
12
T T T V T I P I S A W G C P T T K C A S V V K P C N D
38
50.0%
NZ_BQME02000001.1 and 1 other:
NZ_BQME02000001.1 Lanthipeptides: MFF31_RS04085_lanthipeptide
Lanthipeptides: MFF31_RS04085_lanthipeptide
9
T V T I P I S A A I C P T T Q C A S I V R P C N
32
T+ I P I S A C P T T+C A S I V C N
6
T I I I P I S L A A C P T T R C A S I V S S C N
29
50.0%
NZ_CP040417.1 and 7 others:
NZ_CP040417.1 Lanthipeptides: FE328_RS09035_lanthipeptide NZ_CP040419.1 Lanthipeptides: FE326_RS02890_lanthipeptide NZ_CP040419.1 Lanthipeptides: FE326_RS02890_lanthipeptide NZ_CP040421.1 Lanthipeptides: FE324_RS02830_lanthipeptide NZ_CP040421.1 Lanthipeptides: FE324_RS02830_lanthipeptide NZ_CP040422.1 Lanthipeptides: FE323_RS02865_lanthipeptide NZ_CP040422.1 Lanthipeptides: FE323_RS02865_lanthipeptide
Lanthipeptides: FE328_RS09035_lanthipeptide
9
T V T I P I S A A I C P T T Q C A S I V R P C N N
33
T +P I S A I C P+T+C A S I R P C N
4
T S L V P I S L A I C P S T K C A S I T R P C N K
28
50.0%
NZ_WIXN01000006.1 and 1 other:
NZ_WIXN01000006.1 Lanthipeptides: GHD25_RS06900_lanthipeptide
Lanthipeptides: GHD25_RS06900_lanthipeptide
2
A E P Q G T P T V T I P I S A A I C P T T Q C A S I V R P C N N
33
A P P T I P+S A+C P T T C S P C N
3
A T P D T H P T T I I P V S L A V C P T T T C R S F S S P C P N
34

#### MIBiG 4.0 matches for NP440_RS09140

27.0%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
10
V T I P I S A A I C P T T Q C A S
26
V + +S A A C P T T+C S
19
V A V G V S A A F C P T T K C T S
35
17.6%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
18
I C P T T Q C A S
26
C P T T+C S
16
F C P T T K C T S
24
allorf_1820488_1820661
Leader:
MGIEPTCAGA
Core:
T I R C V N H F A T T A I L A G V V G I E P T S K V L E T F V L P L N Y T P M I F Y K W W R E
Core with dehydrations:
Dhb I R Cys V N H F A Dhb Dhb A I L A G V V G I E P Dhb Dha K V L E Dhb F V L P L N Y Dhb P M I F Y K W W R E

#### antiSMASH-DB 4.0 matches for allorf_1820488_1820661

100.0%
NZ_CP101913.1 and 1 other:
NZ_CP101913.1 Lanthipeptides: allorf_1820488_1820661_lanthipeptide
Lanthipeptides: allorf_1820488_1820661_lanthipeptide
1
T I R C V N H F A T T A I L A G V V G I E P T S K V L E T F V L P L N Y T P M I F Y K W W R E
47
T I R C V N H F A T T A I L A G V V G I E P T S K V L E T F V L P L N Y T P M I F Y K W W R E
1
T I R C V N H F A T T A I L A G V V G I E P T S K V L E T F V L P L N Y T P M I F Y K W W R E
47
17.0%
NZ_NGNA01000004.1:
Lanthipeptides: A5881_RS20710_lanthipeptide
15
A G V V G I E P T S K V L E T F V L P L N Y T P M I F Y K
43
G V V ++ +P++Y T + Y K
4
Q G T V S N I E N K N V C D S L E I P V S Y T H L D V Y K
32
12.8%
NZ_BDUD01000001.1 and 1 other:
NZ_BDUD01000001.1 Lanthipeptides: allorf_2999243_2999452_lanthipeptide
Lanthipeptides: allorf_2999243_2999452_lanthipeptide
2
I R C V N H F A T T A I L A G V
17
+R C+N+F T I +
18
L R C L N Y F V E T R I F T S L
33

#### MIBiG 4.0 matches for allorf_1820488_1820661

8.5%
BGC0000581.6 (AAD28494.1):
Lasso peptide: microcin J25
37
T P M I F Y K
43
T P+ F Y
15
T P I S F Y G
21
allorf_1821134_1821229
Leader:
MIILNRMTGS
Core:
T A G L L P L E E T A T K K Q P K I R V C
Core with dehydrations:
Dhb A G L L P L E E Dhb A Dhb K K Q P K I R V Cys

#### antiSMASH-DB 4.0 matches for allorf_1821134_1821229

100.0%
NZ_CP101913.1 and 1 other:
NZ_CP101913.1 Lanthipeptides: allorf_1821134_1821229_lanthipeptide
Lanthipeptides: allorf_1821134_1821229_lanthipeptide
1
T A G L L P L E E T A T K K Q P K I R V C
21
T A G L L P L E E T A T K K Q P K I R V C
1
T A G L L P L E E T A T K K Q P K I R V C
21
allorf_1841364_1841480
Leader:
MDKGLDSDFFAEECQGG
Core:
H D I P P G G I K M T G C S V L S R T R K
Core with dehydrations:
H D I P P G G I K M Dhb G Cys Dha V L Dha R Dhb R K

#### antiSMASH-DB 4.0 matches for allorf_1841364_1841480

100.0%
NZ_CP101913.1:
Lanthipeptides: allorf_1841364_1841480_lanthipeptide
1
H D I P P G G I K M T G C S V L S R T R K
21
H D I P P G G I K M T G C S V L S R T R K
1
H D I P P G G I K M T G C S V L S R T R K
21
28.6%
NZ_CP012109.1:
Lanthipeptides: allorf_5215572_5215661_lanthipeptide
4
P P G G I K M T G C S V
15
P P G + G C V
9
P P G H V T T R G C H V
20
22.7%
NZ_CP062006.1:
Lassopeptides: IFE19_RS17845_lassopeptide
1
H D I P P G
6
+D I P P G
16
Y D I P P G
21
with 1 more sequence matches
14.5%
NZ_JAIHBQ010000001.1:
Lanthipeptides: allorf_7016711_7016908_lanthipeptide
3
I P P G G I K M T G C S V L S R T R K
21
+P P G + G S S T R+
10
L P P G Q V A E C G F S E P S V T R R
28
allorf_1841460_1841675
Leader:
MQGWYILNAILKG
Core:
M I A T N I A P N I A S T T A T T F P F I N L C R F G V A V T F I K R R K T D V D E I L N C S Q V T F R L F P C S R
Core with dehydrations:
M I A Dhb N I A P N I A Dha Dhb Dhb A Dhb Dhb F P F I N L Cys R F G V A V Dhb F I K R R K Dhb D V D E I L N Cys Dha Q V Dhb F R L F P Cys Dha R

#### antiSMASH-DB 4.0 matches for allorf_1841460_1841675

100.0%
NZ_CP101913.1:
Lanthipeptides: allorf_1841460_1841675_lanthipeptide
1
M I A T N I A P N I A S T T A T T F P F I N L C R F G V A V T F I K R R K T D V D E I L N C S Q V T F R L F P C S R
58
M I A T N I A P N I A S T T A T T F P F I N L C R F G V A V T F I K R R K T D V D E I L N C S Q V T F R L F P C S R
1
M I A T N I A P N I A S T T A T T F P F I N L C R F G V A V T F I K R R K T D V D E I L N C S Q V T F R L F P C S R
58
19.0%
NZ_JAAOYX010000001.1:
Lanthipeptides: FHS47_RS11835_lanthipeptide
19
P F I N L C R F G V A V T F I K R R K T D V D E I L N C S Q V T
50
P +L G A T + T D+ + N C S T
4
P A G S L Y T E G H A Q T V M A M T S T D I A L V S N C S S C T
35
17.2%
NZ_CP058255.1:
Lanthipeptides: HW369_RS18920_lanthipeptide
4
T N I A P N I A S T T A T T F P F I N L C R
25
T P N S+ T F P F I+ C+
6
T K D C P N T V S S V C V T F P F I S A C K
27

#### MIBiG 4.0 matches for allorf_1841460_1841675

6.9%
BGC0000477.3 (ACA04491.1 (core 1)):
Cyanobactin: patellin 2 or patellin 3
17
T F P F I N L C
24
T P L C
1
T L P V P T L C
8

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 23.12 out of 30.25
Confidence: medium
ZuR variant 2
Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 28.44 out of 33.14
Confidence: medium
Additional weak hits (5):
LuxO
Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 22.66 out of 26.12
Confidence: weak
NrdR
Description: Represses ribonucleotide reductase encoding genes
Species: Streptomyces coelicolor
Score: 21.02 out of 27.18
Confidence: weak
NtrC
Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 20.16 out of 29.72
Confidence: weak
OsdR
Description: Development and stress management regulator
Species: Streptomyces coelicolor
Score: 16.99 out of 30.12
Confidence: weak
OsdR
Description: Development and stress management regulator
Species: Streptomyces coelicolor
Score: 17.35 out of 30.12
Confidence: weak
Lanthipeptides
TFBS Finder
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

NP440_RS09135 - Class II
  Cleavage pHMM score: -2.10
  RODEO score: 0
  Monoisotopic mass: 3455.4 Da
  Molecular weight: 3457.9 Da
  Number of bridges: 5
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3475.9 Da N = 1
NP440_RS09140 - Class II
  Cleavage pHMM score: -2.20
  RODEO score: 0
  Monoisotopic mass: 3254.7 Da
  Molecular weight: 3256.7 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3274.7 Da N = 1
    3292.7 Da N = 2
    3310.8 Da N = 3
    3328.8 Da N = 4
allorf_1820488_1820661 - Class II
  Cleavage pHMM score: -5.60
  RODEO score: 0
  Monoisotopic mass: 5297.9 Da
  Molecular weight: 5301.2 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    5319.2 Da N = 1
    5337.2 Da N = 2
    5355.3 Da N = 3
    5373.3 Da N = 4
    5391.3 Da N = 5
    5409.3 Da N = 6
allorf_1821134_1821229 - Class II
  Cleavage pHMM score: -4.00
  RODEO score: 0
  Monoisotopic mass: 2241.3 Da
  Molecular weight: 2242.7 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2260.7 Da N = 1
    2278.7 Da N = 2
allorf_1841364_1841480 - Class II
  Cleavage pHMM score: -2.00
  RODEO score: 0
  Monoisotopic mass: 2180.2 Da
  Molecular weight: 2181.6 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2199.6 Da N = 1
    2217.6 Da N = 2
    2235.6 Da N = 3
allorf_1841460_1841675 - Class II
  Cleavage pHMM score: -6.00
  RODEO score: 0
  Monoisotopic mass: 6309.4 Da
  Molecular weight: 6313.4 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    6331.4 Da N = 1
    6349.4 Da N = 2
    6367.4 Da N = 3
    6385.4 Da N = 4
    6403.5 Da N = 5
    6421.5 Da N = 6
    6439.5 Da N = 7
    6457.5 Da N = 8
NP440_RS09135 - Class II
  Cleavage pHMM score: -2.10
  RODEO score: 0
  Monoisotopic mass: 3455.4 Da
  Molecular weight: 3457.9 Da
  Number of bridges: 5
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3475.9 Da N = 1
NP440_RS09140 - Class II
  Cleavage pHMM score: -2.20
  RODEO score: 0
  Monoisotopic mass: 3254.7 Da
  Molecular weight: 3256.7 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3274.7 Da N = 1
    3292.7 Da N = 2
    3310.8 Da N = 3
    3328.8 Da N = 4
allorf_1817119_1817316 - Class II
  Cleavage pHMM score: -4.00
  RODEO score: 0
  Monoisotopic mass: 3305.8 Da
  Molecular weight: 3307.9 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3325.9 Da N = 1
allorf_1818003_1818074 - Class II
  Cleavage pHMM score: -4.30
  RODEO score: 0
  Monoisotopic mass: 1422.8 Da
  Molecular weight: 1423.7 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1441.7 Da N = 1
    1459.7 Da N = 2
    1477.7 Da N = 3
allorf_1818328_1818426 - Class II
  Cleavage pHMM score: -5.40
  RODEO score: 0
  Monoisotopic mass: 814.4 Da
  Molecular weight: 814.9 Da
  Number of bridges: 1
allorf_1818804_1818965 - Class II
  Cleavage pHMM score: -6.00
  RODEO score: 0
  Monoisotopic mass: 4103.0 Da
  Molecular weight: 4105.4 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4123.4 Da N = 1
    4141.5 Da N = 2
    4159.5 Da N = 3
allorf_1819068_1819298 - Class II
  Cleavage pHMM score: -6.20
  RODEO score: 0
  Monoisotopic mass: 4499.4 Da
  Molecular weight: 4502.1 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4520.1 Da N = 1
    4538.1 Da N = 2
    4556.1 Da N = 3
    4574.1 Da N = 4
    4592.2 Da N = 5
    4610.2 Da N = 6
    4628.2 Da N = 7
    4646.2 Da N = 8
    4664.2 Da N = 9
allorf_1820059_1820208 - Class II
  Cleavage pHMM score: -0.70
  RODEO score: 0
  Monoisotopic mass: 2160.2 Da
  Molecular weight: 2161.5 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2179.6 Da N = 1
allorf_1820488_1820661 - Class II
  Cleavage pHMM score: -5.60
  RODEO score: 0
  Monoisotopic mass: 5297.9 Da
  Molecular weight: 5301.2 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    5319.2 Da N = 1
    5337.2 Da N = 2
    5355.3 Da N = 3
    5373.3 Da N = 4
    5391.3 Da N = 5
    5409.3 Da N = 6
allorf_1821134_1821229 - Class II
  Cleavage pHMM score: -4.00
  RODEO score: 0
  Monoisotopic mass: 2241.3 Da
  Molecular weight: 2242.7 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2260.7 Da N = 1
    2278.7 Da N = 2

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
ColR | Phenol-responsive regulator
ZuR variant 2 | Zinc-responsive repressor

NZ_CP101913.1 - Region 5 - ectoine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,018,520 - 2,028,906 nt. (total: 10,387 nt) Show pHMM detection rules used
ectoine: ectoine_synt

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Transferases: aminotransferase
NP440_RS10105: aminotransferase class-III

smcogs
  SMCOG1013: aminotransferase class-III

Hydrolases: amidase deacetylase
NP440_RS10115: polysaccharide deacetylase

smcogs
  SMCOG1235: polysaccharide deacetylase

NP440_RS10130: amidase

smcogs
  SMCOG1105: amidase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ectoine | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000855.3 |  | 0.73 | other (other) | ectoine | Methylomicrobium kenyense
BGC0000859.3 |  | 0.72 | other (other) | ectoine | Methylomicrobium alcaliphilum
BGC0000856.3 |  | 0.72 | other (other) | ectoine | Methylophaga thalassica
BGC0000852.5 |  | 0.71 | other (other) | ectoine | Sporosarcina pasteurii
BGC0000853.3 |  | 0.68 | other (other) | ectoine | Streptomyces anulatus
BGC0002052.3 |  | 0.68 | other (ectoine) | ectoine | Streptomyces sp.
BGC0000858.3 |  | 0.67 | other (other) | ectoine | Methylobacter marinus
BGC0000857.3 |  | 0.64 | other (other) | ectoine | Methylophaga alcalica
BGC0000854.3 |  | 0.59 | other (other) | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000860.3 |  | 0.50 | other (other) | ectoine | Methylarcula marina

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000855.3 |  | 0.73 | other (other) | ectoine | Methylomicrobium kenyense
BGC0000859.3 |  | 0.72 | other (other) | ectoine | Methylomicrobium alcaliphilum
BGC0000856.3 |  | 0.72 | other (other) | ectoine | Methylophaga thalassica
BGC0000852.5 |  | 0.71 | other (other) | ectoine | Sporosarcina pasteurii
BGC0000853.3 |  | 0.68 | other (other) | ectoine | Streptomyces anulatus
BGC0002052.3 |  | 0.68 | other (ectoine) | ectoine | Streptomyces sp.
BGC0000858.3 |  | 0.67 | other (other) | ectoine | Methylobacter marinus
BGC0000857.3 |  | 0.64 | other (other) | ectoine | Methylophaga alcalica
BGC0000854.3 |  | 0.59 | other (other) | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000860.3 |  | 0.50 | other (other) | ectoine | Methylarcula marina

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 17.88 out of 20.97
Confidence: medium
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 21.67 out of 28.19
Confidence: medium
AfsR
Description: Pleiotropic regulatory for antibiotic production
Species: Streptomyces coelicolor
Score: 19.28 out of 23.05
Confidence: medium
ArgR
Description: Regulator of arginine biosynthesis genes
Species: Streptomyces coelicolor
Score: 18.80 out of 20.01
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.52 out of 26.06
Confidence: medium
Additional weak hits (2):
HipB
Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 22.53 out of 33.73
Confidence: weak
GnfM
Description: Regulator of nitrogen-fixation genes
Species: Geobacter sulfurreducens PCA
Score: 20.88 out of 27.55
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
AfsR | Pleiotropic regulatory for antibiotic production
ArgR | Regulator of arginine biosynthesis genes
CcpA | Catabolite control protein A
MogR | Repressor of flagellar motility genes
ZuR variant 1 | Zinc-responsive repressor

NZ_CP101913.1 - Region 6 - terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,776,402 - 2,797,289 nt. (total: 20,888 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Transferases: carboxylase
NP440_RS13820: acetyl-CoA carboxylase biotin carboxylase

smcogs
  SMCOG1090: acetyl-CoA carboxylase biotin carboxylase

Ligases: synthetase
NP440_RS13790: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002397.2 |  | 0.47 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.44 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0002398.2 |  | 0.39 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana
BGC0002284.3 |  | 0.35 | other (other) | corynecin III, corynecin I, corynecin II | Rhodococcus sp. H-CA8f
BGC0001910.4 |  | 0.33 | terpene | cyslabdan A, cyslabdan B, cyslabdan C | Streptomyces cyslabdanicus
BGC0000234.5 |  | 0.32 | PKS | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0001605.3 |  | 0.32 | terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0000678.5 |  | 0.31 | terpene | pentalenolactone | Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0000665.5 |  | 0.31 | other (other), terpene | xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C | Streptomyces sp. HKI0576
BGC0000528.5 |  | 0.31 | ribosomal | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002397.2 |  | 0.47 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.44 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0002398.2 |  | 0.39 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana
BGC0002284.3 |  | 0.35 | other (other) | corynecin III, corynecin I, corynecin II | Rhodococcus sp. H-CA8f
BGC0001910.4 |  | 0.33 | terpene | cyslabdan A, cyslabdan B, cyslabdan C | Streptomyces cyslabdanicus
BGC0000234.5 |  | 0.32 | PKS | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0001605.3 |  | 0.32 | terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0000678.5 |  | 0.31 | terpene | pentalenolactone | Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0000665.5 |  | 0.31 | other (other), terpene | xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C | Streptomyces sp. HKI0576
BGC0000528.5 |  | 0.31 | ribosomal | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP

Genes with terpene domains:
NP440_RS13790: PT_FPPS_like
Domain 1 (34 - 295): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:
  DMAPP, IPP → FPP

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
VqsM
Description: Regulator of quorum-sensing signalling systems
Species: Pseudomonas aeruginosa PAO1
Score: 19.19 out of 20.47
Confidence: strong
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.08 out of 23.79
Confidence: medium
LexA variant 2
Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 21.85 out of 24.78
Confidence: medium
Additional weak hits (4):
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.88 out of 30.25
Confidence: weak
FuR variant 2
Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 23.05 out of 32.74
Confidence: weak
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.53 out of 30.25
Confidence: weak
CopR
Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 24.31 out of 30.97
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
IolR | Regulator of the inositol catabolism
LexA variant 2 | Repressor of DNA damage response
VqsM | Regulator of quorum-sensing signalling systems

NZ_CP101913.1 - Region 7 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,272,235 - 3,313,401 nt. (total: 41,167 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
NP440_RS16300: aldehyde dehydrogenase

smcogs
  SMCOG1017: aldehyde dehydrogenase

Ligases: synthase
NP440_RS16305: hydroxymethylglutaryl-CoA synthase

smcogs
  SMCOG1043: hydroxymethylglutaryl-CoA synthase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002561.3 |  | 0.41 | other (other) | phenazine SA, phenazine SB, phenazine SC | Streptomyces sp.
BGC0000205.3 |  | 0.40 | PKS | bryostatin | Candidatus Endobugula sertula
BGC0000313.4 |  | 0.36 | NRPS | beauvericin | Beauveria bassiana
BGC0000286.3 |  | 0.36 | PKS | viguiepinol | Streptomyces sp. KO-3988
BGC0001080.5 |  | 0.35 | other (phenazine) | endophenazine A, endophenazine B | Streptomyces anulatus
BGC0000889.5 |  | 0.35 | other (other) | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0002525.3 |  | 0.34 | PKS | fusarubin, 1233A, 1233B, NG-391, lucilactaene | Fusarium sp.
BGC0000934.4 |  | 0.34 | other (phenazine) | 5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G | Kitasatospora sp. HKI 714
BGC0001592.5 |  | 0.34 | other (other) | ferroverdin, bagremycin | Streptomyces lunaelactis
BGC0002262.2 |  | 0.33 | PKS | trienylfuranol A, sporothriolide, dihydrosporothriolide, deoxysporothric acid, dihydroisosporothric acid, sporothric acid, isosporothric acid, sporochartine B | Hypomontagnella monticulosa

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002561.3 |  | 0.41 | other (other) | phenazine SA, phenazine SB, phenazine SC | Streptomyces sp.
BGC0000205.3 |  | 0.40 | PKS | bryostatin | Candidatus Endobugula sertula
BGC0000313.4 |  | 0.36 | NRPS | beauvericin | Beauveria bassiana
BGC0000286.3 |  | 0.36 | PKS | viguiepinol | Streptomyces sp. KO-3988
BGC0001080.5 |  | 0.35 | other (phenazine) | endophenazine A, endophenazine B | Streptomyces anulatus
BGC0000889.5 |  | 0.35 | other (other) | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0002525.3 |  | 0.34 | PKS | fusarubin, 1233A, 1233B, NG-391, lucilactaene | Fusarium sp.
BGC0000934.4 |  | 0.34 | other (phenazine) | 5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G | Kitasatospora sp. HKI 714
BGC0001592.5 |  | 0.34 | other (other) | ferroverdin, bagremycin | Streptomyces lunaelactis
BGC0002262.2 |  | 0.33 | PKS | trienylfuranol A, sporothriolide, dihydrosporothriolide, deoxysporothric acid, dihydroisosporothric acid, sporothric acid, isosporothric acid, sporochartine B | Hypomontagnella monticulosa

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.35 out of 20.97
Confidence: strong
PsrA
Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 20.38 out of 25.88
Confidence: medium
PerR
Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 24.68 out of 28.14
Confidence: medium
CRP
Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.26 out of 19.26
Confidence: strong
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.05 out of 20.97
Confidence: strong
CRP
Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.55 out of 19.26
Confidence: medium
AbrC3
Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 16.22 out of 18.16
Confidence: strong
Additional weak hits (3):
HipB
Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 22.53 out of 33.73
Confidence: weak
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.22 out of 30.25
Confidence: weak
HexR
Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 25.45 out of 31.73
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
AbrC3 | Antibiotic production activator
CRP | Cyclic AMP receptor protein
CcpA | Catabolite control protein A
PerR | Peroxide regulator
PsrA | Oleic acid responsive regulator

NZ_CP101913.1 - Region 8 - terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,426,712 - 3,449,024 nt. (total: 22,313 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Ligases: synthetase
NP440_RS17000: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000616.4 |  | 0.40 | ribosomal | amylocyclicin | Bacillus velezensis FZB42
BGC0000906.3 |  | 0.38 | other (other) | heme D1 | Heliophilum fasciatum
BGC0002584.2 |  | 0.36 | ribosomal | azolemycin B, azolemycin A, azolemycin D, azolemycin C | Streptomyces sp. FXJ1.264
BGC0000905.5 |  | 0.36 | other (other) | heme D1 | Heliobacillus mobilis
BGC0001456.3 |  | 0.35 | terpene | isorenieratene | Streptomyces argillaceus
BGC0000664.5 |  | 0.34 | terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000497.3 |  | 0.34 | ribosomal | BHT-Aα, BHT-Aβ | Streptococcus ratti
BGC0001779.5 |  | 0.33 | ribosomal | siamycin | Streptomyces nodosus
BGC0000537.3 |  | 0.33 | ribosomal | nisin U | Streptococcus uberis
BGC0001789.3 |  | 0.33 | ribosomal | suicin 90-1330 | Streptococcus suis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000616.4 |  | 0.40 | ribosomal | amylocyclicin | Bacillus velezensis FZB42
BGC0000906.3 |  | 0.38 | other (other) | heme D1 | Heliophilum fasciatum
BGC0002584.2 |  | 0.36 | ribosomal | azolemycin B, azolemycin A, azolemycin D, azolemycin C | Streptomyces sp. FXJ1.264
BGC0000905.5 |  | 0.36 | other (other) | heme D1 | Heliobacillus mobilis
BGC0001456.3 |  | 0.35 | terpene | isorenieratene | Streptomyces argillaceus
BGC0000664.5 |  | 0.34 | terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000497.3 |  | 0.34 | ribosomal | BHT-Aα, BHT-Aβ | Streptococcus ratti
BGC0001779.5 |  | 0.33 | ribosomal | siamycin | Streptomyces nodosus
BGC0000537.3 |  | 0.33 | ribosomal | nisin U | Streptococcus uberis
BGC0001789.3 |  | 0.33 | ribosomal | suicin 90-1330 | Streptococcus suis

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP
diterpene precursor |  | GGPP | C20 | acyclic | PP
sesterterpene precursor |  | GFPP | C25 | acyclic | PP
triterpene precursor |  | HPP | C30 | acyclic | PP

Genes with terpene domains:
NP440_RS17000: PT_FPPS_like
Domain 1 (511 - 738): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: unknown

Reactions:
  IPP, DMAPP → FPP
  IPP, DMAPP → GGPP
  IPP, DMAPP → GFPP
  IPP, DMAPP → HPP

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 24.69 out of 27.78
Confidence: strong
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.11 out of 27.78
Confidence: medium
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.12 out of 20.97
Confidence: strong
ANR
Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 21.45 out of 26.33
Confidence: medium
AbrC3
Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 17.35 out of 18.16
Confidence: strong
ArcA
Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 20.02 out of 21.55
Confidence: medium
CatR
Description: H2O2-responsive repressor
Species: Streptomyces coelicolor
Score: 20.67 out of 25.31
Confidence: medium
Additional weak hits (1):
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 21.51 out of 29.25
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
GFPP | Geranylfarnesyl diphosphate
GGPP | Geranylgeranyl diphosphate
HPP | Hexaprenyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
ANR | Anaerobic transcriptional regulator
AbrC3 | Antibiotic production activator
ArcA | Repressor of carbon oxidation
CatR | H2O2-responsive repressor
CcpA | Catabolite control protein A
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria

NZ_CP101913.1 - Region 9 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,554,665 - 3,564,967 nt. (total: 10,303 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
No tailoring functions detected.
Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002439.3 |  | 0.20 | other (other) | diastaphenazine, izumiphenazine C | Streptomyces diastaticus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002439.3 |  | 0.20 | other (other) | diastaphenazine, izumiphenazine C | Streptomyces diastaticus

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.08 out of 26.06
Confidence: medium
Additional weak hits (3):
DosR
Description: Hypoxia stress response regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 20.70 out of 29.51
Confidence: weak
MntR
Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 26.24 out of 39.62
Confidence: weak
RpoN
Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 15.81 out of 18.46
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
MogR | Repressor of flagellar motility genes