LOCUS       NZ_CP076385            22574 bp    DNA     linear   CON 27-AUG-2024
DEFINITION  Streptomyces sp. G11C(2021) chromosome.
ACCESSION   NZ_CP076385
VERSION     NZ_CP076385.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. G11C(2021)
  ORGANISM  Streptomyces sp. G11C(2021)
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7137224)
  AUTHORS   Undabarrena,A., Serna,N., Zamora-Leiva,L., Cumsille,A., Gonzalez,V.,
            Valencia,R., Ugalde,J., Reyes,F., Olano,C., Salas,J.A. and Camara,B.
  TITLE     Towards deciphering Streptomyces albidoflavus metabologenomics:
            insights into a new member of the tetrahydroisoquinoline family
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7137224)
  AUTHORS   Undabarrena,A., Serna,N., Zamora-Leiva,L., Cumsille,A., Gonzalez,V.,
            Valencia,R., Ugalde,J., Reyes,F., Olano,C., Salas,J.A. and Camara,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUN-2021) Laboratorio de Microbiologia Molecular y
            Biotecnologia Ambiental, Universidad Tecnica Federico Santa Maria,
            Av. Espana 1680, Valparaiso 2340000, Chile
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024499195.1-RS_2024_08_27
            Annotation Date                   :: 08/27/2024 07:37:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,192
            CDSs (total)                      :: 6,097
            Genes (coding)                    :: 5,931
            CDSs (with protein)               :: 5,931
            Genes (RNA)                       :: 95
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 166
            CDSs (without protein)            :: 166
            Pseudo Genes (ambiguous residues) :: 0 of 166
            Pseudo Genes (frameshifted)       :: 66 of 166
            Pseudo Genes (incomplete)         :: 127 of 166
            Pseudo Genes (internal stop)      :: 16 of 166
            Pseudo Genes (multiple problems)  :: 38 of 166
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:57:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2897298
            Orig. end                         :: 2919872
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP076385.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22574
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="13"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22574
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22574
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12574](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12574)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            394..1842
                     /locus_tag="KNZ81_RS12400"
                     /old_locus_tag="KNZ81_12330"
     CDS             394..1842
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507348.1"
                     /locus_tag="KNZ81_RS12400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12330"
                     /product="MFS transporter"
                     /protein_id="WP_215221754.1"
                     /transl_table=11
                     /translation="MRRAARVVGRALRTPVTGPARGIRKVTHAQGAGESGLGRLIELHG
                     VNGAGDVMITVALASTVFFSVPTDEARGRVALYLAVTMLPFTLLAPVVGPLLDRLPHGR
                     RAAMAGSMLARAVLALVLSGAVATGSLEMYPAALGVLVASKAYGVVRSAVVPRLLPQGF
                     SLVKANSRVTLGGLLATGVAAPVGAGLQMIGPGWPLYGACLLFLGGAFLSFRLPPKVDS
                     ARGERRALLAADEQHLAAAVDARWDPVAEPVAEPAATGADRSDGTRNRGRERDRDKERR
                     RKGPGLRTVGPAVTHALAANACVRCQSGFLIFFLAFLLREHPLTGQSAAVSLAVVGVAA
                     GAGNALGTAVGAWLRARAPEVIIVTVVGALVAVAVSAAVFFGAAVVAVLGAVAGFTQAL
                     AKLSLDALIQRDVPELVRTSAFARSETLLQMAWVVGGAIGIALPLRGPLGLSVGALIVA
                     LGWLTTVRALMASARRGASHPRVA"
     gene            1872..2396
                     /locus_tag="KNZ81_RS12405"
                     /old_locus_tag="KNZ81_12335"
     CDS             1872..2396
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415563.1"
                     /locus_tag="KNZ81_RS12405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12335"
                     /product="hypothetical protein"
                     /protein_id="WP_023417790.1"
                     /transl_table=11
                     /translation="MTSLPRGGAARQFSPATRRGFAVLGAVSAGLLVLSACDKPTAVAT
                     VTIGSDSVNSEATCWNGGSKIDEKKLQQCLQDKGEGDSGNGAEVKTVKVDTEADVHIGV
                     DPKIADKGWTILMNGQPLTDASNKTFRTIPGSVFFNQQYGASGDSTVLSILENDGSSAT
                     GLWSFKLEKES"
     gene            2417..3142
                     /locus_tag="KNZ81_RS12410"
                     /old_locus_tag="KNZ81_12340"
     CDS             2417..3142
                     /EC_number="3.2.2.26"
                     /GO_function="GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010643335.1"
                     /locus_tag="KNZ81_RS12410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12340"
                     /product="futalosine hydrolase"
                     /protein_id="WP_023417791.1"
                     /transl_table=11
                     /translation="MRLLVATAVPPERDAVARAFGAPDTPEETALPGAVLLRTPGADVL
                     AAGVGPAAAASATSAALTAARLAGNPYDLVVSAGIGGGFAERAPVGAVVAADRIVAADL
                     GAETPEGFVPVTGLGFGTDVHVPPAALVEAAREAGLVPGAVLTVSTVTGSAGRASELLA
                     RHPSAVAEAMEGFGVAEAAAAHGVPVLEIRAISNAIGPRDRDAWRIPAALTALTSAFVR
                     LAPAEAGSPFALARARLVP"
     gene            3210..4106
                     /locus_tag="KNZ81_RS12415"
                     /old_locus_tag="KNZ81_12345"
     CDS             3210..4106
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415567.1"
                     /locus_tag="KNZ81_RS12415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12345"
                     /product="1,4-dihydroxy-6-naphthoate synthase"
                     /protein_id="WP_023417792.1"
                     /transl_table=11
                     /translation="MSESGTGGGVRGTADEAGRLSIAYSPCPNDTFVFDAVAHGRVPGA
                     PALDVTFADIDLTNGMAERGEYDVLKVSYAALPWLLDEYALLPCGGALGRGCGPLVLTR
                     EASLPGALAGRTVAVPSERSTAYLLFRLWAADQVPGGVGEIVVMPFHEIMPAVRDGKVD
                     AGLVIHEARFTYQNYGLHKLADMGEHWEATTGLPIPLGAIIARRSLGAGRLTALAQALR
                     TSVRMAWDDPAASRPYVMAHAQEMDADVADQHIGLYVNEFTADLGEDGYAAVRGLLTRA
                     AAEGLVPPLAPDALRFP"
     gene            complement(4194..4577)
                     /locus_tag="KNZ81_RS31135"
                     /old_locus_tag="KNZ81_12350"
     CDS             complement(4194..4577)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642928.1"
                     /locus_tag="KNZ81_RS31135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12350"
                     /product="cold-shock protein"
                     /protein_id="WP_023417793.1"
                     /transl_table=11
                     /translation="MPTGKVKWFNSEKGFGFLSRDDGGDVFVHSSVLPAGVEALKPGQR
                     VEFGVVAGQRGDQALSVVLLDPAPSVAAAQRRKPDELASIVQDLTTVLENVSRSLERGR
                     YPDKASGAKVAGMLRAVADQLDV"
     misc_feature    complement(4625..4634)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.3"
                     /tool="antismash"
     gene            4719..4970
                     /locus_tag="KNZ81_RS12425"
                     /old_locus_tag="KNZ81_12355"
     CDS             4719..4970
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950020.1"
                     /locus_tag="KNZ81_RS12425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12355"
                     /product="hypothetical protein"
                     /protein_id="WP_215221735.1"
                     /transl_table=11
                     /translation="MSDTTQQTPAPGDRLVKTGGIVFIIGALATLITVAPLFLGSDPFP
                     TAAYLVSMLMGVGFLIAGAGLVRSISAQRRETRAAVEG"
     gene            5241..5912
                     /locus_tag="KNZ81_RS12430"
                     /old_locus_tag="KNZ81_12360"
     CDS             5241..5912
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142169.1"
                     /locus_tag="KNZ81_RS12430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12360"
                     /product="response regulator transcription factor"
                     /protein_id="WP_215221734.1"
                     /transl_table=11
                     /translation="MSRVQVIHSSGVLRSALVALLERERFQVTGSAGFTRASSGTTAAP
                     AAVTVVDSSCPVGAAHLERRSLQGSAKEPTHATPALAAARPGLGLAGAGGGRAALVVLA
                     GAEHSGVLRLAYAAGALGLVDRDGPAGHLATAIRLAAGGGRYLDDGLAVSLLRAMDMPL
                     SPREVRVLSRAAQGDSVAEIARGLCLSHGTVRNYIASATRKVGARNRVDAIRISRAAGW
                     V"
     gene            complement(5887..7911)
                     /locus_tag="KNZ81_RS31140"
                     /old_locus_tag="KNZ81_12365"
     CDS             complement(5887..7911)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890596.1"
                     /locus_tag="KNZ81_RS31140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12365"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_285903477.1"
                     /transl_table=11
                     /translation="MTDRHAPGATPRPLLRPALTFARRRKGPLGTLAAWSLLESARTFL
                     TGYAVARALDDGFLASDVRTGLLWLLALAAAALAGGLADAGVFRSLGSVIEPLRDSLVR
                     RVVRATLTRAVTSPTPADTARVSRLTAQTEIARDAAGGVLLTVRSFLFTSVGALTGLAA
                     LSPRLLPLVLIPLAAGLALFAATLRPMATRQRDLLDADEHLAAFAGRTDHAARDIAATG
                     AAPSVTAEAAPLITAEATAASALARWSAVRVTALGLAAHLPVATLLLAAPTLLSTGLTP
                     GALLAALTYVTTALLPAVNALLTALGTAGSRLLVVLHRLLGEEGDVRGRQADVLGVTDR
                     VRGPGASSHGRADEGPAIPAPPLPGPGHAPEPSRAEPSALGPRPTRPAPPAATLRGVTF
                     AYGPDATPVLDHLDLTVQPGEHLLVVGPSGAGKSTLLALLAGTAHPRHGQIHLGGHTAR
                     HARTLGTAARVLVPQEPYIFEAPLRDNLTYLAPDAPGSRITEALDTFALTSLATDALRP
                     LRPDRLTPSERRRIALARAWLTPSPLLLLDEPTAHLDAGARAATEPAFASHPATVITVS
                     HHFPVPEPGQRVLLLDGATPYLGTHASLLQESALYRELAAEGGAAFDGGDPEHRVDLGV
                     SGEQPRPGALTTRPEPTRQGPPPPRPGPQQPLRPTPPRG"
     gene            complement(7908..9629)
                     /locus_tag="KNZ81_RS12445"
                     /old_locus_tag="KNZ81_12370"
     CDS             complement(7908..9629)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359196.1"
                     /locus_tag="KNZ81_RS12445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12370"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_252922933.1"
                     /transl_table=11
                     /translation="MTAAPADADRARAAPGPPPDEGRLLREAVRRGRGPAALVLAATVL
                     GAAAAVTLPLALGRAVDLLIARADAGFWVLLCSALIAAEVATDALVARTGGRTGAATTA
                     WLRRRALAGFLAAPPAATTGTGLPTRLTANALDAGTAPVAAATAAAAGLAPLGGLAGLF
                     LVDPWAGAAFVCGVPLLLMILRALLRDGRAALTTYQEEQGRMARLLTGALTGAATIAAA
                     GTARAEERRVLAPLAGMRAAGERTWRVQGRAAGLSGALMPLLVAAVLAVGGVRLVAGHL
                     TPGDLLALSRYAVLAAGAGALAGALNGWVRAKAGTARVETVTALPPTPHGTRDLPPHGD
                     GTLALCGVHVTRDGIPLLHDITLTLPGGTTTALVGPSGAGKSLLAAVAGRLTDPDQGSV
                     LLDGTDLRTLSADALRRAVAYAFERPALFGTTVADAVACGPLPEADLRQALRRAAADTF
                     TDRLPHGTRTPLAEAPLSGGELQRLGLARAFTRPTRLLILDDATSSLDTVTAHLVGRAL
                     TEAPGTRLTVTHRLSAAARADQVVWLDKGRVRGTGPHHTLWHDPAYRAVFGTETDT"
     gene            complement(9790..9921)
                     /locus_tag="KNZ81_RS12450"
                     /old_locus_tag="KNZ81_12375"
     CDS             complement(9790..9921)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611153.1"
                     /locus_tag="KNZ81_RS12450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12375"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_008415578.1"
                     /transl_table=11
                     /translation="MALLDLQAMDTPQEEAVGDLATGSQISLLICEYSSLSVTLCTP"
     CDS_motif       complement(9856..9921)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQAMDTPQEEAVGDLAT"
                     /locus_tag="KNZ81_RS12450_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9790..9855)
                     /prepeptide="core"
                     /locus_tag="KNZ81_RS12450_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="30.10"
                     /molecular_weight="2088.4"
                     /monoisotopic_mass="2087.1"
                     /core_sequence="GSQISLLICEYSSLSVTLCTP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQAMDTPQEEAVGDLAT"
                     /leader_location="[9855:9921](-)"
                     /alternative_weights="2106.4"
                     /alternative_weights="2124.5"
                     /alternative_weights="2142.5"
                     /alternative_weights="2160.5"
                     /alternative_weights="2178.5"
     gene            complement(10001..12574)
                     /gene="lanKC"
                     /locus_tag="KNZ81_RS12455"
                     /old_locus_tag="KNZ81_12380"
     CDS             complement(10001..12574)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507351.1"
                     /locus_tag="KNZ81_RS12455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12380"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_215222411.1"
                     /sec_met_domain="micKC (E-value: 6.3e-226, bitscore: 750.7,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3.8e-12, bitscore: 44.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4e-05, bitscore: 21.0,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPEYALYSGADRWFYDTPRRAGRAGDGNGNDGHRYALALRPAPR
                     GWESAERGDWFSLAPAGRQLPAQGWKIHVSATPDNAEQVLETVAGICQERATAFKFLAG
                     PALLLHRNTKYADRAGSGKFVTVYPATTAACGELAAELADALKGSAGPVVLSDLRWGEG
                     PVHVRYGAFAPRFTRTADGSLVPAVADPTGRLVPDTRGPAFRLPDWVALPDFLRPHAEA
                     RAAQGTNGLPYTVERALHFSNGGGVYAGSHRETGEAVVLKEGRPYAGLAADGADAVTRL
                     EREYAALRALEGLACVPRVHGLHTVGEHRFLAMEFIPGTPLNTVFARRFPLSAVEPAAG
                     ALAEHTAWALRTHQLVTEAVEALHARGIAFGDLHMNNIMVAPDQLSVTLLDFEAATPAA
                     ERRPQIVANPAFVAPPHLRGTEVDRYALACLRLALFVPLTTLLPLDRDKAAHLADLAAD
                     RYGIDRALFDEAVTELAGPARAEAATPRGRPPVSATDWPAARDSMVAALLASATPDRDD
                     RYFPGDIAQFATPAGGQSYGYGAAGVLHALHTVGARCEEAEEWLIRTTRRPASGTPAGF
                     YDGLTGIAWTLDRLGHREDALRLAHLVAAEPLDALGPGLHSGAPGVALALRDLADGADD
                     PALGKAADRAEAAALRSAAPGGKAGLLHGPAGTALLCLRRHARTGEPALLDTAATALRQ
                     ELSRCVPGPDGSLVVSEARRTMPYLGSGSAGIAMVLDDYLAHRPDPAFEEARTALLRAT
                     GSAFYIQPGLFRGVAGLLLHLARTTTPVDRAARTALLARQTALLDWHALTYEGQLAYPG
                     EQLTRLSMDLSTGTAGVLLALAATHGEPAAHLPFLPPLRRPTDRP"
     gene            complement(12769..13743)
                     /locus_tag="KNZ81_RS12460"
                     /old_locus_tag="KNZ81_12385"
     CDS             complement(12769..13743)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019761721.1"
                     /locus_tag="KNZ81_RS12460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12385"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_215222410.1"
                     /transl_table=11
                     /translation="MTRRTARPLLAATGALALAVTLTACGSGEETAADAGKDAGATRTV
                     KTAMGEVEVPEAPKRVVVLDTAELDSALTLGVKPVGAVRSDAAGGFAGYLPQRELAGIE
                     NVGVIAQPNLEAIAALKPDLILTSKVRDEARYAQLSKIAATVMTENTGYPWKENFQLHA
                     EALGKQKEADRATAAYEKRTAEVTEAVGGPAKAKETEVNVVRFVEGADIRIYGRKNYIG
                     TLLADVGLGRPAVTDKAADGFSYDVSPEKIDLADADVVFTATYGDPEKAKETRTTRSAL
                     WRSLDAVKSGAVHKVEDELWIQGIGYTAAQQILDQLEEALTPS"
     gene            complement(13740..14597)
                     /locus_tag="KNZ81_RS12465"
                     /old_locus_tag="KNZ81_12390"
     CDS             complement(13740..14597)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950013.1"
                     /locus_tag="KNZ81_RS12465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12390"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_023417801.1"
                     /transl_table=11
                     /translation="MTRPAARLTARDLTLAYEDRTVVPGLDLDVPDGRVTVIIGPNACG
                     KSTTLRALGRLLRPAGGAVLLDGTELARLPTRQIARRIGLLPQTPVAPEAITVADLVAR
                     GRQPHQRWWQQWSAEDERAVTEAMARTATTDLADRPVDALSGGQRQRVWIAMALAQETD
                     LLLLDEPTTYLDLAHQVEVLDLVRRLNREQGRTVVLVLHDLNQAARYADHLIAFREGRV
                     VAEGAPAEVVTAGLVREIFGLECVVVPDPVTGSPLVVPGAPWDARQPAPEPAAPTREES
                     RATP"
     gene            complement(14594..15685)
                     /locus_tag="KNZ81_RS12470"
                     /old_locus_tag="KNZ81_12395"
     CDS             complement(14594..15685)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379708.1"
                     /locus_tag="KNZ81_RS12470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12395"
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="WP_215222409.1"
                     /transl_table=11
                     /translation="MSGTVLKAGPAPARVRPAGYVPVRLGAVSLLVPVRAVATGAVLAA
                     VLAVVCVAYLSVGESFVAPGSVVDVLLGRASPDTLVVGELRLPRMVAGLYVGAAFGIAG
                     ALIQTVARNPLASPDLIGVSQGASAATVAALTFGVTSYAVLPWISLGGGLLAALLVYLF
                     AWRGGLQATRFVLVGVGFAVALRALTTLFLTKGDQTVAQQAQVWMSGSLNGRAWPEAAL
                     VGWTLLAALPALVWAARVQRTVTLDDATATGLGAHLGRARLGLVLIGVVLASVATGAAG
                     PVDFVALLAPQIARRLTRTAQIPLVCSALAGAVTVVAADLLARRLFAPTELPVGVLTAA
                     VGAPYLIWLLVTRHGPRATGGTS"
     gene            complement(15682..16746)
                     /locus_tag="KNZ81_RS12475"
                     /old_locus_tag="KNZ81_12400"
     CDS             complement(15682..16746)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018896364.1"
                     /locus_tag="KNZ81_RS12475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12400"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_215222408.1"
                     /transl_table=11
                     /translation="MPPAPPAAPPLAKAPPPASRPRRDSAVHRAALTVAALVALLVAVV
                     LSLAVGARTVAPGTVVEALFQGATGPDAEVVREMRLPRTLIGVMVGAALAVAGTALQGI
                     TRNPIADPGILGISQGASVGVVLAIAFAGVHTLAGYVWFAFAGAGLAAVAVYAVAAGGR
                     GGATPVKLALSGAAVNALLVSVTTAVLTTSSSALDEFRFWNVGALQGRDAEVAVQVWPF
                     LLVGLALVASSARGLDALALGEDVAKGLGQRVGAVRITAGAGAAVLTGVGVAAAGPVAF
                     VGLAVPHLVRHLAGGDHRWVLPLAALTGPVMLLASDTVGRVLFPPGEVPAGVMTALIGV
                     PFLVALVRGRAVTG"
     misc_feature    16834..16854
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    complement(16835..16855)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.7"
                     /tool="antismash"
     gene            16884..17570
                     /locus_tag="KNZ81_RS12480"
                     /old_locus_tag="KNZ81_12405"
     CDS             16884..17570
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016472413.1"
                     /locus_tag="KNZ81_RS12480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12405"
                     /product="HAD family hydrolase"
                     /protein_id="WP_033950669.1"
                     /sec_met_domain="HAD_2 (E-value: 5.4e-08, bitscore: 31.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEHLTSPAAPTPSGPAVPAARPAPGGAGPVVGFDLDMTLIDSRP
                     GIGAAYRVLAAETGVPIDVDLVVSRLGPPLETELACWFPAEQVPAAAARYREVYPSTAI
                     APSPALPGAAQALEAVRAHGGRSLVVTAKNEEHARLHLDHLGLRAELVVGSLWAEAKGG
                     ALRAQGATVYVGDHVGDVRGAQAAGAFSVAVATGGCTPDELRAAGADVVLPDLAAFPAW
                     LAEFAH"
     gene            18065..19087
                     /locus_tag="KNZ81_RS12485"
                     /old_locus_tag="KNZ81_12410"
     CDS             18065..19087
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507354.1"
                     /locus_tag="KNZ81_RS12485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12410"
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="WP_033950664.1"
                     /transl_table=11
                     /translation="MKQPARTAGGAVAEEARPVEGVEGDEPGRAAEWWVALRRTPGAFW
                     RDDVSDFAAALTYYAILAVLPALLVVVIAFGLVSPDTAERFVGQVTAWAPGGSGASLRE
                     VLTRVVRVDSTAWTLLVTGGASALWSASSYLAVSRRALHRMYGVRDRRSPWGKAHRIVA
                     TALALLSLLLVSSLLLMLTEPVAESIGRLLGLDAGVAWAWSVVRWPLLLCLVACLVVVV
                     FRNGPVAARRRAHSIPGGVLAATLWLTASAGLALYASVLSTYSRLYGSLAGIVVFLVWL
                     WLSNVALLLGAQFTAELCRAEGGPGAPACRPGPVEGMAAEDVPADTDAAQEHGRAPTGA
                     "
     gene            19208..21133
                     /locus_tag="KNZ81_RS12490"
                     /old_locus_tag="KNZ81_12415"
     CDS             19208..21133
                     /GO_component="GO:0005777 - peroxisome [Evidence IEA]"
                     /GO_function="GO:0003997 - acyl-CoA oxidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006635 - fatty acid beta-oxidation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008406865.1"
                     /locus_tag="KNZ81_RS12490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12415"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_285903507.1"
                     /transl_table=11
                     /translation="MTHGQLGPIHDSLATVTLQSVITEREIPLRHSSISASASVADDLL
                     FATRGEEHLRWRELFSTEEFGHRDLPHRERVELSYRRLRTVAAAIPDPRALALSAPALT
                     ALHEWAGPADPGMATLASIHYNLFLGSLLDHDHAERDLGPWLRMDRIGTFLCTEAEHGN
                     DAVNMETTAEYDRASRQFVLNTPDPGAAKWMPNTSLTGGPKDAVVAARLLVDGRDLGIF
                     LFLTPLSDERGHLPGVSVERLPHTSGAPVDHCATRFHHVRLPHSAMLQGDHGRLSPEGE
                     FESTLGSPRIRFLRSIGRVSMGKLCMSGYSLGATRQAIAVAVRHGSTRLTSGMTKGRRV
                     PLMAHRSHHEPLLDALATTYAATLLHRSVVRQWEVAEEAEREEVDRLVAVTKGWITWAA
                     RETMTTCRERCGAKGLLLTQGIAGQLAANEGTITAEGDNKVIWVKAAGELLMGGFTPKP
                     PSETAPEQRSLRDGTHLQDLMADVERIWHERARTRLRSGGVRGNPMARWNGAVTPALEL
                     VAAHAHRLAGEALLEGTDRVSADEAERIRDLHRLFALRQVAAHSGELLAGERLTAEQVR
                     RLPDEVERVVADLEPHILALTERFFVPENLPGSDPAGLVEAAPEALAAGTEARTGGLRE
                     SEPDAA"
     misc_feature    complement(19223..19236)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     misc_feature    complement(19254..19267)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.71"
                     /tool="antismash"
     misc_feature    19259..19261
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(21246..22562)
                     /locus_tag="KNZ81_RS12495"
                     /old_locus_tag="KNZ81_12420"
     CDS             complement(21246..22562)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010643357.1"
                     /locus_tag="KNZ81_RS12495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_12420"
                     /product="cytochrome P450"
                     /protein_id="WP_023417808.1"
                     /transl_table=11
                     /translation="MHDANFAADPQAVYEQLREQGPAGPVELAPGVDATLVVGYETALR
                     VLQNPTSFPRDARRWAALNEGRVPMDSPVLPMMAYRPNALFTDGAVHLRLRKAVTDSLA
                     KLNITRIRRDVEPIADYLIDQFSERGRADLLAEYAKLLPLLLFNKLFGCPAEIGDTLTT
                     EMSAMFDGKDPVRTKARLDACLMQLIAIKRREPADDVISWLIQHPAGLTDEELKDQLVM
                     LMGAGIEPERNLIGNALLELLSGGAGGRGAGMMVEEAVDHVLWHRTPIANYAAHYPAQD
                     TDFGNGVIAPAGSPVLISFAGANSDPALAEARRSAGRGAHLAWGAGSHACPAKDPAQVI
                     AVTAVEKILNALPDLTLGVPEEELQWRPGPFHRALVSLPVAFSPTPATRMAAALQSRGV
                     PQQQVAPATPQPQHTAPASSDGGGRRKGFWSSFLDIFRV"
ORIGIN
        1 acgccgtctc acgagtcgca tgcggcggag acgggcagcg gacggagcgg accgctgggc
       61 cgcgtcgacg tccgcgcccg atcgtccagg gcacgcccac gcgaaccatt ctgggggatc
      121 gcgaagaggc gcgcggccgg gagtaccgtc gcaggcgcgt gagtgcacgc taccctctcg
      181 cggccccgtc tcccacaccg acgtgggaag ccgggccgct caggggcgtc ggcggcgcgt
      241 cgtacgggtg cgggcgagcg gcccggcgag gggtggcgcg gccccgcttc ggccacaggg
      301 gttgctcggg acacttcggg tcatactcgg cccgccaggg ggcactatca ccacgtgacc
      361 gcctcaggct cgccacgcgt ggagcgcagc ccggtgcgca gggccgcccg ggttgtgggc
      421 cgcgcgctgc ggactcccgt gacgggcccg gcgcgcggca tccgcaaggt gacgcacgcg
      481 cagggcgcgg gcgagtcggg gctcgggcgg ctgatcgagc tgcacggggt gaacggcgcc
      541 ggcgacgtga tgatcacggt ggcgctggcc tcgacggtct tcttctcggt gccgacggac
      601 gaggcgcggg gccgggtggc gctctacctg gccgtgacga tgctcccgtt cacgctgctg
      661 gcgccggtgg tgggtccgct gctggaccgg ctgccgcacg ggcggcgggc ggcgatggcc
      721 gggtcgatgc tggcccgggc ggtactggcg ctggtgctgt cgggggcggt ggcgaccggg
      781 agcctggaga tgtacccggc cgcgctcggc gtcctggtgg cctcgaaggc gtacggggtg
      841 gtgcgcagtg ccgtggtgcc ccggctgttg ccgcaggggt tctcgctggt caaggccaat
      901 tcgcgggtga cgctcggcgg gctgctggcc accggggtgg cggcgccggt cggggcgggg
      961 ctccagatga tcggcccggg gtggccgttg tacggggcgt gtctcctctt cctcggcggc
     1021 gcgttcctct cgttccggct gccgccgaag gtcgactcgg cgcgcggcga gcggcgggca
     1081 ctgctggcgg cggacgagca gcatctcgcg gcggccgtgg acgcccgctg ggacccggtc
     1141 gccgagccgg tcgccgagcc ggcggcgacg ggggccgacc gcagtgacgg gaccaggaac
     1201 agggggaggg agagggacag ggacaaggag cggcggcgga aggggccggg gctcaggacg
     1261 gtggggccgg cggtgacaca cgcgctggcg gccaacgcct gtgtgcggtg tcagagcggc
     1321 ttcctcatct tcttcctggc gttcctgctg cgcgagcatc cgctgacggg gcagagcgcg
     1381 gcggtgtcgc tggcggtggt cggtgtggcg gcgggggcgg ggaacgcgct ggggacggcg
     1441 gtcggggcgt ggctgcgggc ccgggcgccg gaggtgatca tcgtgacggt ggtgggggcg
     1501 ctggtggcgg tcgcggtgtc ggcggcggtg ttcttcggtg cggcggtggt ggcggtactg
     1561 ggggcggtgg ccgggttcac ccaggcgctg gccaagctgt cgctggacgc gctgatccag
     1621 cgtgatgtgc cggagctggt gcggacgtcg gcgttcgccc gttcggagac cttgctgcag
     1681 atggcgtggg tggtgggcgg agcgatcggg atcgcgttgc cgctgcgcgg gccgctgggg
     1741 ctgagcgtgg gcgcgctgat cgtggcactc ggctggctga cgaccgtacg ggcgctcatg
     1801 gcgtcggcca gacgcggcgc gtcgcacccc cgcgtggcgt gaccctccaa cgggcccgat
     1861 agccttcgcc catgacatcc ctgccccgcg gcggagccgc acgtcagttc agcccggcca
     1921 cgcgccgcgg gttcgccgtc ctcggcgcgg tgtccgccgg cctgctcgtc ctgtccgcct
     1981 gcgacaagcc gacggcggtc gccaccgtca ccatcggctc cgactcggtg aactccgagg
     2041 cgacgtgctg gaacggcggc tccaagatcg acgagaagaa gctccagcag tgcctccagg
     2101 acaagggtga gggcgactcc ggcaacggcg ccgaggtgaa gaccgtgaag gtcgacaccg
     2161 aggccgacgt gcacatcggc gtcgacccga agatcgccga caagggctgg acgatcctca
     2221 tgaacggcca gccgctgacc gacgcgtcca acaagacctt ccggacgatc cccggcagcg
     2281 tcttcttcaa ccagcagtac ggcgcctccg gcgactccac cgtcctctcc atcctggaga
     2341 acgacggcag ctccgccacc ggcctgtggt cgttcaagct ggagaaggag tcctgacccg
     2401 cctgcccacg cccgccgtgc ggctgctcgt cgccaccgct gtcccgcccg agcgggacgc
     2461 ggtggcgcgc gcgttcgggg cgccggacac cccggaggag acggccctgc ccggcgcggt
     2521 gctgctgcgc accccgggcg ccgacgtact ggccgccggg gtcggcccgg ccgccgcggc
     2581 gagcgccacc tcggcggcgc tgacggcggc ccggctcgcg ggcaacccct acgacctggt
     2641 cgtctcggcc gggatcggcg gcggtttcgc cgagcgggct ccggtgggcg cggtggtggc
     2701 cgcggaccgg atcgtcgcgg ccgacctggg cgccgagaca ccggagggct tcgttccggt
     2761 gaccgggctc ggtttcggta cggacgtgca cgtgccgccg gccgcgctgg tcgaggcggc
     2821 ccgcgaggcc gggctcgtgc cgggcgcggt gctcaccgtc tccacggtga cgggcagcgc
     2881 gggccgtgcc tccgagttgc tggcccgcca cccgtcggcg gtggccgagg cgatggaggg
     2941 cttcggtgtc gcggaggcgg ccgccgcaca cggcgtaccg gtgctggaga tccgcgccat
     3001 ctccaacgcc atcggcccgc gcgaccgtga cgcctggcgc attcccgccg ccctcaccgc
     3061 gctgacctcg gccttcgtcc gcctcgcccc cgccgaggcg gggagcccct tcgccctggc
     3121 ccgcgcccgg ctcgtaccgt gagcggtggc agtacgcgcg gcacaggcgg cgcgagcagt
     3181 ggcagcagca gggaaggcga ggcggcgaca tgagtgagag cggtacgggc ggcggcgtcc
     3241 gggggacggc ggacgaggcc gggcggctga gcatcgccta ctccccctgc cccaacgaca
     3301 cgttcgtctt cgacgcggtc gcccacggcc gggtcccggg cgcgccggcg ctcgacgtga
     3361 ccttcgccga catcgacctg accaacggca tggccgagcg cggcgagtac gacgtcctca
     3421 aggtctcgta cgcggcgctg ccctggctgc tcgacgagta cgccctgctg ccgtgcggcg
     3481 gggcgctcgg ccgggggtgc ggcccgctgg tgctgacccg cgaggcctcg ctgccggggg
     3541 cgctggccgg gcggacggtg gcggtgccca gtgagcggtc gacggcctac ctgctcttcc
     3601 ggctctgggc ggcggaccag gtgccgggcg gggtcgggga gatcgtggtg atgccgttcc
     3661 acgagatcat gccggcggtc cgggacggca aggtcgacgc gggcctggtc atccacgagg
     3721 cgcgcttcac ctaccagaac tacggcctgc acaagctggc cgacatgggc gagcactggg
     3781 aggcgacgac gggcctgccg atcccgctcg gcgcgatcat cgcccgccgc tcactcggcg
     3841 ccggccgcct gaccgcactg gcccaggcgc ttcgtacctc ggtccggatg gcgtgggacg
     3901 accccgcagc ctcccgcccg tacgtcatgg cgcacgccca ggagatggac gcggacgtcg
     3961 ccgaccagca catcggcctg tacgtcaacg agttcaccgc cgacctcggc gaggacgggt
     4021 acgcggccgt acgcggcctg ctgacccggg cggcggccga gggcctggtc ccgccgctgg
     4081 ccccggacgc gctgcgtttc ccgtgaccga aacggctgga ccacgtacga cgagaccgcc
     4141 ggatcacgct ggttccggcg gtctcgtcgt aggcgctgaa gggtgcagct cgctcagacg
     4201 tcgagctggt cggcgacggc gcggagcatg ccggcgacct tggcgccgga ggccttgtcc
     4261 gggtaccggc cgcgctccag gctgcggctg acgttctcca ggacggtggt gaggtcctgg
     4321 acgatggagg cgagctcgtc gggcttgcgg cgctgcgcgg cggcgaccga gggcgccggg
     4381 tcgaggagca ccacggaaag tgcctggtca ccgcgttgac cggcgaccac gccgaactcc
     4441 acccgctggc cgggcttgag cgcttcgacg ccggcgggca gcacggacga gtgcacgaag
     4501 acgtcgccgc cgtcgtcgcg ggagaggaag ccgaagccct tctcgctgtt gaaccacttg
     4561 accttgccag tcggcaaagc actgtccctt ctcgccctgc cgccgtccgg ccgcagtgtc
     4621 ctggtcacat atcagggggg atgtacccac ggcgaagcta tcccatccgc tccaccccgg
     4681 cgcggagatt acgggggccg ggcaactacc ctggacccgt gtccgacacc acccagcaga
     4741 ccccggcccc cggcgaccgc ctcgtgaaga ccggcggcat cgtcttcatc atcggcgccc
     4801 tggcgaccct catcaccgtc gcgcccctct tcctcggctc cgacccgttc ccgaccgccg
     4861 cctacctggt ctccatgctg atgggcgtcg gcttcctcat cgcgggagcc gggctggtcc
     4921 gctccatcag cgcgcagcgg cgcgagacgc gggctgccgt cgagggctga gcgccatgcc
     4981 ccgcccggca cgctccggct cacttccgaa cgttccgggc gccacgcgcg cccccttccg
     5041 cgccctcccc cgctctccgg ctcccgccga tgatgggccc gccgccgatc tgcggcgacc
     5101 acggacgccg ccgctccgct ggcggaaccg tttcgccttc cggacggcga cggccgtcgg
     5161 ccaaggctga acagtgaggg cgccgcctcc cacccggagc gcgacgccac gctgagtctc
     5221 cggaagcgga aggcggaacg atgtctcgcg tacaggtgat ccacagctcg ggtgtcctgc
     5281 gatcggccct ggtggccctg ctggaacgcg aaaggttcca ggtcaccggc tcggccggct
     5341 tcacgagagc ctcgtccggc accaccgccg cccccgccgc ggtgaccgtc gtcgacagct
     5401 cctgtcccgt gggagcggcc cacctcgaac gccgctccct gcaaggctcc gccaaggaac
     5461 ccacccacgc cacccccgcc ctcgccgccg cccggccggg gctgggcctc gccggagcgg
     5521 gcggggggcg agcggccctg gtcgtcctcg ccggggccga acactccgga gtcctccgcc
     5581 tcgcctacgc ggccggcgca ctcggcctgg tcgaccgcga cggccccgcc ggccacctgg
     5641 ccaccgcgat acggctggcc gccgggggcg ggcggtacct ggacgacggg ctggcggtga
     5701 gcctgctccg ggcgatggac atgccgcttt caccgcgtga ggtgcgggtg ctgagcaggg
     5761 ccgcgcaggg ggattcggtg gcggagatcg cgcgggggtt gtgcctgtcg cacgggacgg
     5821 tgcggaacta cattgcttcg gccacccgga aggtgggggc caggaatcgg gtggacgcga
     5881 ttcggatcag ccgcgcggcg gggtgggtct gaggggctgc tgcgggcctg gacggggtgg
     5941 gggcgggcct tggcgagtgg gctcggggcg ggtcgtcagt gctcctgggc gtggctgctc
     6001 cccgctcacg ccgaggtcga cgcggtgctc cggatcccca ccgtcgaagg ctgccccacc
     6061 ctccgctgcc agttcccggt acagggccga ctcctgcagc agcgaggcgt gggtccccag
     6121 gtaaggcgtc gccccgtcca ggagcaggac gcgctgcccg ggttcgggta ccggaaagtg
     6181 atggctcacc gtgatcaccg tggccgggtg ggaagcgaaa gctggctccg tggcagcccg
     6241 cgcccccgcg tccaggtggg ctgtgggctc gtccaggagg agcaggggcg aaggcgtcag
     6301 ccacgctcgg gcgagggcga tgcgacggcg ttcggacggg gtgaggcggt ccgggcggag
     6361 agggcggagc gcgtccgtcg cgagggaggt cagggcgaag gtgtcgaggg cttcggtgat
     6421 gcgggagccg ggggcgtccg gggcgaggta ggtgaggttg tcgcggagag gggcctcgaa
     6481 gatgtagggc tcctggggga cgaggacgcg ggcggccgtg ccgagggtgc gggcgtggcg
     6541 ggcggtgtgg cccccgaggt ggatctggcc gtgtcggggg tgggcggtgc cggcgaggag
     6601 ggcgagcaag gtggacttgc ccgcgccgct ggggcctacg accaggaggt gttcgccggg
     6661 ttggacggtg aggtcgaggt ggtcgaggac gggggtggcg tcggggccgt aggcgaaggt
     6721 cacgccgcgc agggtggcgg cggggggtgc cgggcgggtg gggcgaggcc ccagggccga
     6781 gggttccgcg cgggacggct cgggcgcgtg tccggggccg gggagcgggg gcgcggggat
     6841 ggcggggccc tcgtccgccc tcccgtgcga gctggccccc ggcccgcgca cgcggtcggt
     6901 gacccccagt acgtcggcct gcctgccccg cacgtccccc tcctccccca gcagtcggtg
     6961 cagcacgacc agtagccgcg accccgccgt gcccagggcg gtgagcaggg cgttgacggc
     7021 ggggaggagg gcggtggtga cgtaggtgag ggctgcgagg agtgcgccgg gggtgaggcc
     7081 ggtggagagg agggtggggg cggcgaggag gagggtggct acgggtaggt gggcggcgag
     7141 gccgagggcg gtgacgcgga cggctgacca gcgggccagg gcggaggcgg cagtggcctc
     7201 ggcggtgatg aggggggctg cctcggcggt gaccgacggg gctgcgccgg tggcggcgat
     7261 gtcgcgggcg gcgtgatcgg tgcggccggc gaaggcggcg aggtgttcgt cggcgtcgag
     7321 gaggtcgcgt tggcgggtgg ccatggggcg gagggtggcg gcgaacaggg ccaggccggc
     7381 ggccaggggg atcaggacga gggggaggag cctcggggag agcgccgcca gtcccgtgag
     7441 ggcgccgacc gaggtgaaga ggaaggagcg caccgtcagc aggacgccgc cggccgcgtc
     7501 gcgggcgatc tcggtctggg cggtgaggcg ggagacgcgt gccgtgtcgg ccggggtggg
     7561 tgaggtgacg gcccgggtca gggtggcgcg gaccacgcgg cggaccaggg agtcgcgcag
     7621 gggctcgatc acgctgccga gtgagcggaa gaccccggcg tcggcgaggc ccccggcgag
     7681 ggctgcggcg gcgagggcga gcagccagag gaggcccgtg cggacgtctg aggcgaggaa
     7741 gccgtcgtcc agggcgcggg cgacggcgta gccggtgaga aaggtacggg ccgattcgag
     7801 gagggaccag gcggccagcg tcccgagcgg acccttgcgg cggcgggcga aggtgagggc
     7861 ggggcgcagg agggggcggg gcgtggcgcc aggggcatgc cggtcggtca tgtgtccgtc
     7921 tccgtgccga agaccgcgcg gtaggcgggg tcgtgccaga gggtgtggtg ggggcccgtg
     7981 ccgcgcacgc ggcccttgtc gagccagacg acctggtcgg cccgggcggc ggcggagagg
     8041 cggtgggtga cggtgaggcg ggtgccgggg gcctcggtga gggcgcggcc tacgaggtgg
     8101 gcggtgacgg tgtcgaggct ggaggtggcg tcgtccagga tcaggagacg ggtgggacgg
     8161 gtgaacgccc gtgccaggcc gaggcgttga agttcgccgc cggagagggg ggcttcggcc
     8221 aggggggtgc gggtgccgtg cgggaggcgg tccgtgaagg tgtcggcggc ggcgcggcgc
     8281 agggcttggc ggaggtcggc ctcgggcagg gggccgcagg cgacggcgtc ggcgaccgtc
     8341 gtgccgaaga gggccgggcg ttcgaaggcg tacgcgacgg cgcggcgcag ggcgtcggcg
     8401 gagagggtgc gcaggtcggt tccgtcgagg aggacgctgc cctggtcggg gtcggtgagg
     8461 cggccggcca ccgccgccag cagggacttg ccggcgccgg acgggccgac gagggcggtg
     8521 gtggttccac cggggagggt gagggtgatg tcgtggagga gcggtatgcc gtcgcgggtc
     8581 acgtggaccc cgcacagggc gagggtgccg tcgccgtgcg gggggaggtc gcgcgtcccg
     8641 tggggggtgg gcggcagggc ggtgacggtc tcgacgcggg cggtgcccgc cttggcccgt
     8701 acccagccgt tgagggcgcc ggccagcgct ccggctccgg cggcgaggac ggcgtagcgg
     8761 gagagggcga ggaggtcgcc gggggtgagg tgaccggcga cgaggcgtac gccgccgacg
     8821 gcgaggacgg cggcgaccag gagtggcatc agggcgccgg agaggccggc ggcgcggccc
     8881 tggacgcgcc aggtgcgctc gccggccgcg cgcatcccgg ccagcggggc gaggacgcgg
     8941 cgttcctcgg cgcgggcggt tccggcggcg gcgatggtgg cggcgccggt gagggcgccg
     9001 gtcagcaggc gggccatgcg gccctgttcc tcctggtacg tggtgagggc ggcgcggccg
     9061 tcgcggagca gggcgcgcag gatcatcagg aggagcggga cgccgcagac gaacgcggcg
     9121 ccggcccacg ggtcgacgag gaagagcccg gccagcccgc cgaggggggc gaggccggcg
     9181 gcggcagcgg tggcggcggc gacgggggct gttccggcgt cgagggcgtt ggcggtgagg
     9241 cgggtgggca ggccggtgcc ggtcgtcgcg gcggggggcg cggcgaggaa gccggcgagc
     9301 gcgcggcggc gcagccaggc cgtggtggcg gcgccggtcc ggccgccggt gcgggcgacc
     9361 agggcgtccg tggccacctc ggcggcgatc agcgcgctgc acagcaggac ccagaacccg
     9421 gcgtcggcgc gggcgatgag caggtcgacc gcgcggccga gggcgagggg cagcgtgacg
     9481 gcggcggcgg cgccgagcac ggtggccgcg aggacgaggg ccgcgggccc cctgccccgg
     9541 cgtaccgcct cccgcagcag gcgtccctcg tcgggcggcg ggccgggagc ggcgcgggcc
     9601 cggtcggcgt cggcgggggc ggcggtcatg gctgctccgt tcgggcgggc gggcaggcgg
     9661 gcgggttgtc cgggagcggc gcggaacgcg ggaggtcccg ggcgctgggg cgcccgggac
     9721 caagggctgt cgcacgcgcc cggcccgtgg gggccgggcg cgcggcggac agccgggttc
     9781 agctccgcgt cacggggtgc agagggtgac gctcagcgag ctgtactcgc agatgagcag
     9841 cgagatctgg ctgccggtgg cgaggtcgcc caccgcctcc tcctgcgggg tgtccatcgc
     9901 ctggaggtcg agaagcgcca tgacgtactc cttcgtgtcg agcggtcggg cgaccgccac
     9961 ctgggaaaac gagtggtgct ggtggtgcgc gaccctgggg tcagggccgg tctgtgggcc
    10021 gccggagcgg cgggaggaag ggcaggtgcg cggcgggttc gccgtgtgtc gcggccaggg
    10081 cgagcaggac gccggccgtg ccggtggaga ggtccatcga caggcgggtc aactgttctc
    10141 ctgggtaggc gagctgccct tcgtaggtga gcgcgtgcca gtccagcagg gcggtctggc
    10201 gggccaggag ggcggtgcgg gcggcccggt cgacgggggt ggtggtgcgg gccaggtgga
    10261 ggaggagtcc ggccacgccc cggaagaggc cgggctggat gtagaaggcg gagccggtgg
    10321 cccgcaggag ggcggtccgg gcctcctcga aggcggggtc ggggcggtgg gccaggtagt
    10381 cgtcgaggac catcgcgatg cccgcgctcc cggagccgag gtacggcatg gtccgccggg
    10441 cctcggagac gacgagcgag ccgtccggtc ccggcacgca gcggctcagc tcctggcgga
    10501 gggcggtggc ggcggtgtcg agcagggcgg gttcgccggt acgggcgtgg cggcgcaggc
    10561 agagcagggc ggttccggcc gggccgtgca gcagtccggc cttgccgccg ggggcggcgg
    10621 agcggagtgc ggcggcctcg gcgcggtcgg cggccttgcc gagggcgggg tcgtcggcgc
    10681 cgtcggccag gtcgcgcagg gccagggcga cgccgggggc gccggagtgc aggccgggcc
    10741 cgagtgcgtc gaggggttcg gcggcgacca ggtgggcgag gcgcagggcg tcctcacggt
    10801 ggccgaggcg gtccagggtc caggcgatgc cggtgaggcc gtcgtagaag ccggccgggg
    10861 tgcccgaggc gggccggcgg gtggtgcgga tcagccattc ctcggcctcc tcgcagcggg
    10921 cgccgacggt gtgcagggcg tgcaggacgc cggcggcgcc gtagccgtac gactgtccgc
    10981 cggccggggt ggcgaactgg gcgatgtcgc ccgggaagta gcggtcgtcg cggtcggggg
    11041 tggcggaggc gagcagggcg gccaccatcg agtcgcgggc ggcgggccag tcggtggcgc
    11101 tcaccggcgg gcggccacgg ggtgtcgcgg cctccgccct tgccgggccc gcgagttcgg
    11161 tgaccgcctc gtcgaagagg gcacggtcga tgccgtaccg gtcggcggcg aggtcggcga
    11221 ggtgggccgc cttgtcgcgg tcgaggggca gcagggtggt gagcgggacg aagagggcga
    11281 ggcggaggca ggccagggcg taccggtcga cctctgtgcc gcgcaggtgg ggcggggcga
    11341 cgaaggcggg attggcgacg atctgcgggc ggcgctcggc ggccggggtg gcggcctcga
    11401 agtccagcag ggtgacggag agctggtccg gcgccaccat gatgttgttc atgtgcaggt
    11461 cgccgaaggc gatgccccgg gcgtgcagcg cctcgaccgc ctccgtgacg agctggtggg
    11521 tgcgcagggc ccaggcggtg tgctcggcga gggctccggc ggccggctcg acggcggaga
    11581 gcgggaagcg gcgggcgaag accgtgttga gcggggtgcc ggggatgaac tccatggcca
    11641 ggaagcggtg ttcgcccacg gtgtgcagtc cgtgcacgcg cgggacgcac gccagccctt
    11701 cgagggcgcg cagggccgcg tactcccgct ccagccgggt gaccgcgtcg gccccgtcgg
    11761 cggcgagccc ggcgtacggc cggccctcct tgagcaccac ggcctcaccg gtctcccggt
    11821 gcgaaccggc gtacaccccg cccccgttgg agaagtgcag ggcgcgttcg acggtgtacg
    11881 ggaggccgtt cgtgccctgg gcggcgcggg cctcggcgtg cgggcgcagg aagtcgggga
    11941 gtgccaccca gtcggggagg cggaaggcgg ggccgcgggt gtccgggacg aggcggcccg
    12001 tcgggtcggc caccgccggg accagggagc cgtcggcggt gcgggtgaag cggggcgcga
    12061 aggcgccgta gcggacgtgg accgggccct cgccccagcg caggtcgctg aggacgaccg
    12121 ggcccgcgct gcccttgagg gcgtcggcga gctcggcggc cagttcgccg caggcggcgg
    12181 tggtggccgg gtagacggtg acgaacttgc cgctgccggc gcggtcggcg tacttggtgt
    12241 tgcggtggag cagcagggcg ggcccggcga ggaacttgaa ggcggtggcg cgctcctggc
    12301 agatcccggc gacggtctcc aggacctgct cggcgttgtc cggcgtcgcg gagacgtgga
    12361 tcttccagcc ctgggcgggg agctggcgcc ctgcgggggc gagcgagaac cagtcaccgc
    12421 gctcggcgct ctcccagccc ctgggggcgg gccgcagggc gagggcgtaa cggtggccgt
    12481 cgttgccgtt gccgtcaccc gcacggccgg cccggcgcgg ggtgtcgtag aaccagcggt
    12541 cggcaccgct gtagagcgcg tactccggat tcaccggtcc ccctcgcctt ctgcgttccc
    12601 gtgccgtgct gtgcgtcggt gacgggttcc acactgcccg tggccgggcg gcgccggtaa
    12661 gtaacgcttg tcatcggcga gttgtgggaa acgcatggtc cgaacgggtc atggcggacg
    12721 ggctcggagc gtgctgcggg ggccggtggc tgccggagcg agggcggctc aggagggggt
    12781 cagggcctcc tccagctggt ccaggatctg ctgggcggcg gtgtaaccga tgccctggat
    12841 ccacagctcg tcctcgacct tgtggacggc gccggacttg acggcgtcca gggagcgcca
    12901 gagggcggac ctggtggtcc gcgtctcctt ggccttctcc gggtcgccgt aggtggcggt
    12961 gaagaccacg tcggcgtcgg ccaggtcgat cttctcgggg ctcacgtcgt acgagaagcc
    13021 gtcagcggcc ttgtcggtga cggcggggcg gccgaggccg acgtcggcga ggagggtgcc
    13081 gatgtagttc ttcctgccgt agatgcggat gtcggctccc tcgacgaagc ggaccacgtt
    13141 gacctcggtc tccttcgcct tcgccgggcc gccgaccgcc tcggtgacct cggcggtccg
    13201 cttctcgtag gcggcggtgg cgcggtcggc ctccttctgc ttgccgaggg cctcggcgtg
    13261 cagctggaag ttctccttcc aggggtagcc ggtgttctcc gtcatcacgg tggcggcgat
    13321 cttgctgagc tgggcgtagc gggcctcgtc gcggaccttc gaggtgagga tcaggtccgg
    13381 cttgagcgcc gcgatcgcct ccaggttggg ctgggcgatg acgccgacgt tctcgatccc
    13441 ggccagttcc ctctgcggca ggtagcccgc gaacccgccg gcggcgtcgg agcggacggc
    13501 gccgaccggc ttcactccga gggtgagcgc ggagtccagc tcggcggtgt ccaggacgac
    13561 gacccgcttc ggcgcctcgg ggacctccac ctcgcccatc gcggtcttga cggtacgggt
    13621 ggctcccgcg tccttgcccg cgtcggcggc ggtctcctcg ccggagccgc aggcggtgag
    13681 ggtgacggcg agcgcgaggg cgccggtggc ggcgaggagc ggacgggcgg tacgtcgggt
    13741 catggcgtgg ccctgctttc ttctcgggtg ggggcagcgg gttccggcgc cggctgccgg
    13801 gcgtcccagg gcgcccccgg gacgacgagc ggggagccgg tgacggggtc ggggacgacg
    13861 acgcactcca ggccgaagat ctcccggacc aggccggcgg tgacgacctc ggcgggggcg
    13921 ccctcggcga cgacgcggcc ctcccggaag gcgatgaggt gatccgcgta gcgggcggcc
    13981 tggttgaggt cgtgcaggac gaggacgacg gtgcggccct gctcgcggtt gaggcggcgg
    14041 accaggtcga ggacctcgac ctggtgggcg aggtcgaggt aggtggtggg ctcgtcgagc
    14101 aggagcaggt cggtctcctg ggcgagggcc atggcgatcc agacgcgctg ccgctggccg
    14161 ccggagaggg cgtccacggg acggtcggcg aggtcggtcg tggcggtgcg ggccatcgcc
    14221 tcggtgaccg cccgctcgtc ctccgccgac cactgctgcc accaccgctg gtgcggctgg
    14281 cggccgcgcg ccaccaggtc ggccacggtg atcgcctccg gtgccaccgg ggtctgcggc
    14341 agcagcccga tccgccgggc gatctgccgg gtgggcagcc gggccagttc cgtgccgtcg
    14401 agcaggacgg cgccgccggc ggggcggagc agccggccga gcgcccgcag ggtggtggac
    14461 ttgccgcagg cgttgggccc gatgatgacg gtgacccggc cgtcggggac gtccaggtcg
    14521 aggccgggga cgacggtgcg gtcctcgtag gcgagggtga ggtctcgggc ggtgaggcgg
    14581 gcggcggggc gggtcatgag gtgcctccgg tggcgcgggg gccgtgtcgg gtgacgagca
    14641 gccagatcag gtacggggcg ccgaccgccg cggtgagcac ccccaccggc agttcggtcg
    14701 gcgcgaagag gcggcgggcc agcaggtcgg cggcgaccac ggtgacggcc ccggccagcg
    14761 cggagcagac cagcgggatc tgcgcggtac gggtcagccg ccgggcgatc tgcggggcga
    14821 ggagcgcgac gaagtcgacg ggcccggccg cgccggtggc gaccgaggcg aggaccacgc
    14881 cgatcaggac gagtccgagg cgggcgcgtc ccaggtgggc gccgagtccc gtcgcggtgg
    14941 cgtcgtccag ggtgacggtg cgctggacgc gggcggccca gaccagcgcg ggcagggcgg
    15001 cgagcagggt ccagccgacg agggcggctt ccggccaggc gcggccgttg agggacccgc
    15061 tcatccacac ctgggcctgc tgggccacgg tctggtcgcc cttggtcagg aagagcgtgg
    15121 tcagcgcccg cagggccacg gcgaaaccga ccccgaccag cacgaaccgg gtggcctgga
    15181 gcccgccccg ccaggcgaag aggtagacga gcagcgccgc gaggagcccg ccgcccaggg
    15241 agatccaggg cagcacggcg tacgaggtga cgccgaaggt cagcgcggcg accgtggcgg
    15301 cgctcgcgcc ctggctgaca ccgatcaggt ccgggctggc cagcgggttc cgggcgacgg
    15361 tctggatgag cgcgcccgcg atcccgaacg ccgccccgac gtacagcccc gccaccatcc
    15421 gcggcagccg cagctccccc accaccagcg tgtccggcga ggcacgcccc agcagcacgt
    15481 cgaccaccga cccgggcgcg acgaagctct cgcccacact caggtacgcc acacagacca
    15541 cggccagcac agccgccagg acggcgccgg tcgcgaccgc ccgcacgggg acgagaagac
    15601 tgacggcccc cagccgtacg gggacgtacc cggcggggcg tacgcgggcg ggggccggcc
    15661 ccgccttcag caccgtgccg ctcacccggt caccgccctg ccccggacca gcgccaccag
    15721 gaagggcacg ccgatcagcg cggtcatgac cccggcgggg acctcgcccg gcgggaagag
    15781 gacgcggccg acggtgtcgg aggcgaggag catcacgggg ccggtcaggg cggccagcgg
    15841 gaggacccag cggtggtcgc cgccggccag gtggcggacg aggtgcggca cggcgaggcc
    15901 gacgaaggcg accggcccgg cggcggccac cccgaccccg gtcagcacgg cggctccggc
    15961 ccccgcggtg atccgtacgg ccccgacccg ctgccccagc cccttcgcca cgtcctcccc
    16021 cagcgccagc gcgtccagcc cccgcgccga ggacgccacc agcgccagcc ccaccagcag
    16081 gaacggccac acctgcacgg ccacctcggc gtcccgcccc tggagcgcgc cgacgttcca
    16141 gaagcggaac tcgtccaggg cgctggaact ggtggtcagc acggcggtgg tgaccgagac
    16201 cagcagggcg ttgaccgcgg cgccgctcag cgccagcttg accggggtcg cgccgccccg
    16261 gccgcccgcc gcgaccgcgt acacggcgac cgccgcgagc cccgcgcccg cgaacgcgaa
    16321 ccagacgtac ccggccaggg tgtgcacccc cgcgaaggcg atggccagga cgaccccgac
    16381 cgaggcgccc tggctgatgc cgagaatgcc cgggtccgcg atcggattac gggtgatgcc
    16441 ctgcagggcg gtcccggcga cggcgagggc ggcgccgacc atcacgccga tcagcgtgcg
    16501 cggcagccgc atctcccgga ccacctcggc gtccggaccc gtggccccct ggaacagggc
    16561 ctccacgacc gtgccggggg ccaccgtacg agcgccgaca gccaggctga ggacgaccgc
    16621 gaccagcagc gccaccagcg ccgccaccgt caaggccgcc cggtgtacgg cgctgtcccg
    16681 gcggggccgg gaggctgggg gcggtgcctt cgccaggggc ggggcggcgg gcggtgcggg
    16741 gggcatcggg tcctttccgg tccgggctgt ctccgggccg gcggccggga gcggacatca
    16801 cggcacaccg ccccaattgc ccgttccgcg acggcactta ggcttggcta agtgtacggc
    16861 cgtcggggct gcacaatgga gggatgcccg agcacctcac ctcccccgcc gcgcccactc
    16921 cctccggccc cgccgtaccg gccgcacgtc cggctccggg cggggccggg cccgtcgtcg
    16981 ggttcgacct cgacatgacg ctgatcgact cccggccggg gatcggggcg gcctatcgcg
    17041 tactcgccgc cgagaccggc gtccccatcg acgtcgacct ggtcgtctcc cggctcgggc
    17101 cgccgctgga gaccgagctg gcctgctggt tcccggccga gcaggtcccc gccgccgccg
    17161 cgcgctaccg cgaggtctac ccgtccaccg cgatagcccc ctcgcccgcc ctgcccgggg
    17221 ccgcgcaggc gctggaggcc gtacgggccc acggtgggcg ctcgctggtc gtcaccgcca
    17281 agaacgagga gcacgcgcgg ctccacctgg accacctcgg cctccgggcc gagctcgtcg
    17341 tgggcagcct ctgggccgag gccaaggggg gtgcgctgcg cgcacagggg gccaccgtgt
    17401 acgtcgggga ccacgtcggc gacgtccgcg gcgcccaggc cgccggggcc ttctccgtgg
    17461 ccgtcgccac cgggggctgc acccccgacg agctccgggc cgccggcgcc gacgtcgtcc
    17521 tccccgacct ggccgccttc cccgcctggc tggcggagtt cgcccactga cccgcctcat
    17581 gcgccggctg ggccgctctt cggctggacc cggtttgccc cgcaccggtc aagggcggcc
    17641 tccaacgccg gccgggccac agggtttcgc ggtgcgttcg ccgtcctggc cgggcggggc
    17701 cgcaccgccc cgaaggctcc cgtcggagcg gggcggcccg gccagaccgg cggcacacac
    17761 ctcgtcgagg tcccgggcaa gctcccggaa gtcacgccag tcctcgggct cgaccccgcg
    17821 cagccgcagc ctctcgccgg cccagacgtc ccccacgacg cccccggctc cgcatccccg
    17881 acgggcactc gggaccggcc cgcacgaccc cgccacggta ccggcgcccc gccccgcccg
    17941 ggccctgcgt accggcggca ccgcccgccc gcgtaccgtg cgacccccgc gcccaggtcg
    18001 gccgtgccac gaacggggta ggcacccctg acccgtaggg caccgggtgc cgcgaggagg
    18061 aacgatgaag caaccggctc ggacagcggg cggggccgtg gccgaggagg cgcggccggt
    18121 ggagggtgtc gagggggacg agccggggcg ggcggcggag tggtgggtgg cgttgcggcg
    18181 gacgccgggg gcgttctggc gggacgacgt ctcggacttc gcggcggcgc tgacctatta
    18241 cgcgatcctc gccgtgctgc cggcgctgct ggtggtcgtg atcgctttcg ggctggtcag
    18301 tccggacacg gcggagcggt tcgtgggcca ggtgacggcg tgggcgccgg gcggctcggg
    18361 ggcctcgttg cgcgaggtgc tgacgcgggt ggtgcgggtc gactcgaccg cctggacact
    18421 gctggtgacc ggcggcgcga gcgcgctctg gtcggcctcc agctacctgg cggtctcgcg
    18481 gcgcgcgctg caccgcatgt acggggtacg ggaccggcgt tcgccgtggg gaaaggcgca
    18541 ccggatcgtg gcgacggccc tggccctgct gtcgctgctg ctggtcagtt cgctgctgct
    18601 gatgctgacc gagccggtgg ccgagtcgat cgggcggctg ctggggctgg acgccggggt
    18661 ggcgtgggcg tggagcgtgg tgcgctggcc gttgctgctc tgcctggtgg cctgtctggt
    18721 cgtggtcgtc ttccggaacg gcccggtggc cgcccgccgc cgcgcccaca gcatccccgg
    18781 cggcgtcctc gccgcgacgc tctggctgac cgcgtcggcg gggctcgcgc tgtacgcctc
    18841 ggtactcagt acgtacagcc gcctctacgg ctcgctcgcg gggatcgtcg tcttcctggt
    18901 gtggctgtgg ctctccaacg tcgcgctgct gctcggcgcc cagttcacgg cggagttgtg
    18961 ccgcgcggag gggggcccgg gcgcaccggc ctgccgcccc gggccggtcg agggcatggc
    19021 cgccgaggac gtgccggccg acaccgacgc cgcccaggag cacgggcgcg cccccaccgg
    19081 cgcgtgatcc ccttccgcct ttcgccctgg cgggggcgtc ccgcaccgca tgagggcaag
    19141 gcggatgatt ccccgcagag ggtgcataca tcccgccagg agctggcctg aactggccgc
    19201 ttgacatatg acacatggtc agttgggccc tatccatgac tccctggcga ccgttacttt
    19261 acaaagtgtg attactgaac gagagattcc gctccgccac agctccatct ccgcctccgc
    19321 ttccgtcgcc gacgacctgc tcttcgcgac acgcggcgaa gagcacctgc gctggcggga
    19381 gctattcagc acggaggagt tcggccaccg ggacttgccc caccgggaaa gggtggagtt
    19441 gtcctatcgg cgcttgcgta ccgtcgccgc cgcgataccc gatccacgcg cgctcgccct
    19501 gagcgcgccg gcgctgaccg cgctccacga gtgggcgggc ccggccgatc ccgggatggc
    19561 cacgctggcc tccatccact acaacctctt cctgggcagc ctcctcgacc acgaccacgc
    19621 ggagcgggac ctggggccgt ggctgcggat ggaccggatc ggcacgttcc tgtgcaccga
    19681 ggccgagcac ggcaacgacg cggtgaacat ggagacgacc gccgagtacg accgcgcctc
    19741 tcgtcagttc gtcctcaaca ccccggaccc gggggcggcc aagtggatgc ccaacacctc
    19801 gctgaccggc ggcccgaagg acgccgtggt ggcggcccgg ctgctggtcg acggccgcga
    19861 cctgggcatc ttcctcttcc tcaccccgct cagcgacgag cgcggccacc tgccgggcgt
    19921 cagcgtcgag cggctgccgc acacgtccgg cgcgcccgtg gaccactgcg ccacccgctt
    19981 ccaccacgtg cggctgccgc acagcgcgat gctccagggc gaccacgggc ggctgagtcc
    20041 ggagggcgag ttcgagagca cgctcgggag cccccgtatc cgcttcctgc gctccatcgg
    20101 ccgggtgtcg atgggcaagc tctgcatgtc cggttacagc ctgggcgcca cccggcaggc
    20161 gatcgcggtc gccgtgcggc acggctccac gcggctgacc tccggcatga ccaaggggcg
    20221 cagggtcccg ctgatggccc accgcagcca ccacgagccg ctgctcgacg cgctcgccac
    20281 cacgtacgcg gcgacgctgc tgcaccgctc ggtggtacgc cagtgggagg tggccgagga
    20341 ggccgagcgc gaggaggtcg accggctggt cgcggtgacc aaggggtgga tcacctgggc
    20401 ggcccgggag accatgacga cctgccgtga gcggtgcggc gccaaggggc tgctgctgac
    20461 gcagggcatc gcgggccagc tcgccgccaa cgagggcacc atcaccgccg agggcgacaa
    20521 caaggtcatc tgggtcaagg ccgccggtga gctgctgatg ggtgggttca ccccgaagcc
    20581 gcccagcgag accgcgcccg agcagcggtc cctgcgggac ggcacgcacc tccaggacct
    20641 gatggcggac gtggagcgga tctggcacga gcgggcccgg acccggctgc gctcgggcgg
    20701 cgtacgcggc aacccgatgg cccgctggaa cggcgccgtc accccggcgc tggagctggt
    20761 cgccgcccac gcgcaccggc tggccgggga ggcgctgctg gagggcaccg accgggtcag
    20821 cgccgacgag gccgagcgca tccgcgacct gcaccggctc ttcgcgctgc gccaggtggc
    20881 ggcgcacagc ggggagttgc tggccggaga gcggctgacg gcggagcagg tgcggcggct
    20941 cccggacgag gtcgagcggg tcgtggcgga cctggagccc cacatcctcg ccctgacaga
    21001 acgtttcttc gtaccggaga acctgcccgg cagcgacccc gccggcctgg tcgaggccgc
    21061 gcccgaggcc ctcgccgccg gcacggaggc ccgtaccggc ggactccggg agagcgagcc
    21121 ggacgcggca tgacgggctg aggcgaacga aggcgtgacg cgggacggcc cgccgcgcgt
    21181 gggcacgacg gaccgtcctt gcgtctcccg tcctccgggc ggcacaccgg ccggaggcgt
    21241 ccgggtcaga cccggaagat gtcgaggaag gagctccaga agcccttcct gcgaccgccg
    21301 ccgtccgagg aggccggggc ggtgtgctgc ggctgcgggg tggcgggtgc cacctgctgc
    21361 tgcgggacgc cccggctctg gagggccgcg gccatccggg tggccggagt cgggctgaag
    21421 gcgaccggca gcgagaccag agcccggtgg aacgggccgg gccgccactg cagttcctcc
    21481 tccgggacgc cgagcgtcag gtccggcagg gcgttgagga tcttctcgac cgcggtgacc
    21541 gcgatgacct gcgccgggtc cttggccggg caggcgtgcg agcccgcgcc ccaggcgagg
    21601 tgggcgccgc gtcccgcgct gcggcgggcc tcggcgaggg cggggtcgct gttggccccg
    21661 gcgaaggaga tcaggacggg gctgccggcg ggcgcgatga caccgttgcc gaagtccgtg
    21721 tcctgggccg ggtagtgggc ggcgtagttg gcgatcgggg tgcggtgcca caggacgtgg
    21781 tcgaccgcct cctcgaccat catcccggcg ccccggccgc ccgcgccgcc ggagagcagt
    21841 tccagcaggg cgttgccgat gaggttgcgc tccggctcga tgccggcgcc catcaacatc
    21901 accagctggt ccttcagctc ctcgtcggtc agcccggccg ggtgctggat gagccaggag
    21961 atgacgtcgt cggccggctc gcggcgcttg atcgcgatga gctgcatcag gcaggcgtcg
    22021 aggcgggcct tggtccgcac cgggtccttg ccgtcgaaca tcgccgacat ctcggtggtg
    22081 agggtgtcgc cgatctcggc cgggcagccg aagagcttgt tgaacagcag cagcgggagc
    22141 agcttggcgt actccgcgag gaggtcggcg cggccgcgct cgctgaactg gtcgatgagg
    22201 tagtcggcga tcggctccac gtcacggcgg atgcgcgtga tgttgagctt ggcgaggctg
    22261 tccgtgaccg ccttgcgcag ccgcaggtgg acggcgccgt cggtgaacag ggcgttcggc
    22321 cggtacgcca tcatcggcag gaccgggctg tccatcggga cgcggccctc gttcagggcc
    22381 gcccagcggc gggcgtcgcg ggggaagctc gtcgggttct ggagaacgcg cagcgccgtc
    22441 tcgtacccca cgaccagcgt cgcgtcgact ccgggggcca gctcgaccgg gccggccggg
    22501 ccctgctcgc gcagctgctc gtagaccgcc tgggggtcgg cggcgaagtt ggcgtcgtgc
    22561 atcgggcatc tgcc
//
