LOCUS       NZ_CP076385            22286 bp    DNA     linear   CON 27-AUG-2024
DEFINITION  Streptomyces sp. G11C(2021) chromosome.
ACCESSION   NZ_CP076385
VERSION     NZ_CP076385.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. G11C(2021)
  ORGANISM  Streptomyces sp. G11C(2021)
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7137224)
  AUTHORS   Undabarrena,A., Serna,N., Zamora-Leiva,L., Cumsille,A., Gonzalez,V.,
            Valencia,R., Ugalde,J., Reyes,F., Olano,C., Salas,J.A. and Camara,B.
  TITLE     Towards deciphering Streptomyces albidoflavus metabologenomics:
            insights into a new member of the tetrahydroisoquinoline family
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7137224)
  AUTHORS   Undabarrena,A., Serna,N., Zamora-Leiva,L., Cumsille,A., Gonzalez,V.,
            Valencia,R., Ugalde,J., Reyes,F., Olano,C., Salas,J.A. and Camara,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUN-2021) Laboratorio de Microbiologia Molecular y
            Biotecnologia Ambiental, Universidad Tecnica Federico Santa Maria,
            Av. Espana 1680, Valparaiso 2340000, Chile
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024499195.1-RS_2024_08_27
            Annotation Date                   :: 08/27/2024 07:37:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,192
            CDSs (total)                      :: 6,097
            Genes (coding)                    :: 5,931
            CDSs (with protein)               :: 5,931
            Genes (RNA)                       :: 95
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 166
            CDSs (without protein)            :: 166
            Pseudo Genes (ambiguous residues) :: 0 of 166
            Pseudo Genes (frameshifted)       :: 66 of 166
            Pseudo Genes (incomplete)         :: 127 of 166
            Pseudo Genes (internal stop)      :: 16 of 166
            Pseudo Genes (multiple problems)  :: 38 of 166
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:57:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1765516
            Orig. end                         :: 1787802
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP076385.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22286
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22286
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22286
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12286](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12286
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(297..512)
                     /locus_tag="KNZ81_RS07330"
                     /old_locus_tag="KNZ81_07330"
     CDS             complement(297..512)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507043.1"
                     /locus_tag="KNZ81_RS07330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07330"
                     /product="acyl-CoA carboxylase subunit epsilon"
                     /protein_id="WP_023416822.1"
                     /transl_table=11
                     /translation="MATPTVPATPEQFLRVEKGHAEPEELAAITALLMARAAAQPAPAA
                     RRGRDRAGWRRLERTPGFRAPHSWQG"
     gene            complement(551..2143)
                     /locus_tag="KNZ81_RS07335"
                     /old_locus_tag="KNZ81_07335"
     CDS             complement(551..2143)
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266768.1"
                     /locus_tag="KNZ81_RS07335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07335"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_164182868.1"
                     /transl_table=11
                     /translation="MTVLDETAESGSEPADARGRVAELHALRQRAEQGPGEKATAAQHA
                     KGKLTARERIALLLDEGSFREVEQLRRHRATGFGLEQKRPHTDGVITGWGTVEGRTVFV
                     YAHDFRIFGGALGEAHATKIHKIMDMAIAAGAPLVSLNDGAGARIQEGVSALAGYGGIF
                     QRNTKASGVIPQISVMLGPCAGGAAYSPALTDFVFMVRETSQMFITGPDVVRAVTGEEI
                     SQNGLGGADVHAETSGVCHFAYDDEETCLAEVRYLLSLLPQNNRENPPAAEATDPAGRR
                     GDALLDLVPADGNRPYDMAKVIEELVDDGDYLEVHERWARNIICALARLDGQVVGIVAN
                     QPQSLAGVLDIEASEKAARFVQMCDAFNIPIVTLLDVPGFLPGVDQEHGGIIRHGAKLL
                     YAYCNATVPRISLILRKAYGGAYIVMDSQSIGADLTYAWPTNEIAVMGAEGAANVIFRR
                     QIAGADDPEAMRARMVKEYKAELMHPYYAAERGLVDDVIDPAETRQVLIDSLAMLRTKH
                     ADLPSRKHGNPPQ"
     gene            complement(2439..2978)
                     /locus_tag="KNZ81_RS07340"
                     /old_locus_tag="KNZ81_07340"
     CDS             complement(2439..2978)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470926.1"
                     /locus_tag="KNZ81_RS07340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07340"
                     /product="hypothetical protein"
                     /protein_id="WP_023416824.1"
                     /transl_table=11
                     /translation="MKIRSALSALALVAGAGFGVIGTATAATAAPAPTSTTAEAGAAAT
                     KITHAQATSRFSSSGITWSSSGGCSNRNVSTCTSFDQLNLATAQGAQTLKSASGCAINI
                     TGGTETGHAGGTYSHWNGYKLDFSKSTCLNNYVTGTFTYIGQRGDGAAQYQSGSGNVYA
                     NEGNHWDVTYYNCGGC"
     gene            3296..3889
                     /locus_tag="KNZ81_RS07345"
                     /old_locus_tag="KNZ81_07345"
     CDS             3296..3889
                     /GO_component="GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414932.1"
                     /locus_tag="KNZ81_RS07345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07345"
                     /product="YceI family protein"
                     /protein_id="WP_023421593.1"
                     /transl_table=11
                     /translation="MGIFGRKNETTDTTVSPDLAALTGTYTLDPTHTTIGFVARHAMVT
                     NVKGGFGDFTGTLTLDGSDPSNSTAEIDVAMDSVDTGNADRDGHLKNADFFKTDEFPKM
                     TFRSTEAEALGGDDYRITGDLTILGTTRPLSIDLEFNGSATDPFGNERVGFEGTASILR
                     SEWGLTWNAALETGGVLVSDKIKLVFDISAIKNA"
     gene            complement(4363..4728)
                     /locus_tag="KNZ81_RS07350"
                     /old_locus_tag="KNZ81_07350"
     CDS             complement(4363..4728)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010641993.1"
                     /locus_tag="KNZ81_RS07350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07350"
                     /product="hypothetical protein"
                     /protein_id="WP_033946836.1"
                     /transl_table=11
                     /translation="MSENVYVGNAPEEAALDAGWIMGHFKALDDPRHNEAVEIKWGVHE
                     AGERRAAWVRGEERQALLVLVSGRFRMQFPERDVVLSEQGQYVIWGKGVDHSWEAEEPS
                     VVMTVRWPSVPGYRVSP"
     gene            4856..5338
                     /locus_tag="KNZ81_RS07355"
                     /old_locus_tag="KNZ81_07355"
     CDS             4856..5338
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-154). E-value: 4e-20.
                     Score: 64.6. Matches aSDomain:
                     nrpspksdomains_KNZ81_RS07355_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414939.1"
                     /locus_tag="KNZ81_RS07355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07355"
                     /product="SRPBCC family protein"
                     /protein_id="WP_026048269.1"
                     /transl_table=11
                     /translation="MRSTAEVSVAAVIEAEPKAVYERVADVASMGRWSPECVRTAAGVG
                     PAPVGAEFKGTNKGPSGRSWSTRCRVMVARSGERFTFRVRFWGMPVATWDYRFRPVGDG
                     TATEVTETAVDQRNRLLWFLGSAVSGVWDRSAHNAETMRETLERLRETLEAERRAG"
     aSDomain        4868..5317
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KNZ81_RS07355_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="4.00E-20"
                     /label="KNZ81_RS07355_Polyketide_cyc2.1"
                     /locus_tag="KNZ81_RS07355"
                     /protein_end="154"
                     /protein_start="4"
                     /score="64.6"
                     /tool="antismash"
                     /translation="AEVSVAAVIEAEPKAVYERVADVASMGRWSPECVRTAAGVGPAPV
                     GAEFKGTNKGPSGRSWSTRCRVMVARSGERFTFRVRFWGMPVATWDYRFRPVGDGTATE
                     VTETAVDQRNRLLWFLGSAVSGVWDRSAHNAETMRETLERLRETLE"
     gene            5386..6066
                     /locus_tag="KNZ81_RS07360"
                     /old_locus_tag="KNZ81_07360"
     CDS             5386..6066
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414941.1"
                     /locus_tag="KNZ81_RS07360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07360"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_033946839.1"
                     /transl_table=11
                     /translation="MSDHQTTGADGEEARARAAVRDAWARIDAWMRAHAPDSYEVLAPP
                     ADPAAVEAAQAELDVRFPADLLASLACHDGLRHWANCLPLRPPLPVADIVDHWQMCVEI
                     DEDNRADEDEPEPEGEEPWWHPQWIPWAQSDGDAQIIDMRPGPGQGRLGMAYHDDCGVF
                     GDGWPSLATYLTEVADVLEKGGAVGGTWAPYLTTAGELWWSLKGETQLNGEPLTPAPAP
                     SAGS"
     gene            complement(6338..7150)
                     /locus_tag="KNZ81_RS07365"
                     /old_locus_tag="KNZ81_07365"
     CDS             complement(6338..7150)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642004.1"
                     /locus_tag="KNZ81_RS07365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07365"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_023421594.1"
                     /transl_table=11
                     /translation="MPDTPDAEGLTVGQASARLDVTVRALHHWDEIGLARPSLRTPAGY
                     RLYTAPDLERLHRIVVYRELGLGLDKIRAVLDDAATDVPAALRAQRAQIAARIDRLQQL
                     GAGLDRMIDAHEHGLLLTAEQQAAIFGPGWSPDGPVQARQRYGDTTQWRQYAERSASRT
                     PEEWQAVADDVARLERALGEAMDSGVTPGSPEANHLVERHREVFASYFPLSRQMQVCLG
                     RMYEGDPGFAAHYDAVRPGLATWFRQLVDAAARAHGIDPDTAIWDEDR"
     gene            complement(7143..7685)
                     /locus_tag="KNZ81_RS07370"
                     /old_locus_tag="KNZ81_07370"
     CDS             complement(7143..7685)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642006.1"
                     /locus_tag="KNZ81_RS07370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07370"
                     /product="VOC family protein"
                     /protein_id="WP_215222198.1"
                     /transl_table=11
                     /translation="MSDDTYYDAFEISPVPAPGPDAVPPEPFRGIYGMPAFVNIPTTDL
                     AASVEFWTRGLGFFELFSIPGTLVHLRRWAFQDVLLVAAESVPEQPPAMSFSFSGVLSQ
                     VDSLVEACRALRPDAVEGPRDTPWNTRDVEVITPENARIVFTAAKPFDPDTQEARNLQA
                     IGITPPGETPGDNERHA"
     gene            7895..8218
                     /locus_tag="KNZ81_RS07375"
                     /old_locus_tag="KNZ81_07375"
     CDS             7895..8218
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893452.1"
                     /locus_tag="KNZ81_RS07375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07375"
                     /product="hypothetical protein"
                     /protein_id="WP_164904412.1"
                     /transl_table=11
                     /translation="MIDGLSGGTLAELARLERTRNHLWPGAVSEAVRAWAGHVRLPRGR
                     TWPHPGHGPCYCCPDPWESRELLDQVARALSRRGARELRRVLAAHDQLWDPAPRTYRGE
                     GPW"
     gene            complement(8297..8722)
                     /locus_tag="KNZ81_RS07380"
                     /old_locus_tag="KNZ81_07380"
     CDS             complement(8297..8722)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414951.1"
                     /locus_tag="KNZ81_RS07380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07380"
                     /product="ATP-binding protein"
                     /protein_id="WP_023416832.1"
                     /transl_table=11
                     /translation="MKTETGLPAHCERFYRRERRSVPAARDFTAAVLDEWDARVRRDDV
                     LLCVSELATNALLHGVPPGRGFRLFVLRADDGGVRVEVHDSGDGRPATRAPGGEAESGR
                     GLLLVSALADDWGVGERDPGKSVWCSFRPVGVGCTGK"
     gene            8835..9653
                     /locus_tag="KNZ81_RS07385"
                     /old_locus_tag="KNZ81_07385"
     CDS             8835..9653
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470914.1"
                     /locus_tag="KNZ81_RS07385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07385"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_023416833.1"
                     /transl_table=11
                     /translation="MQQRKKSSKKVTSWEVVGAQLAEFRRSAGLTQPQLAGTAKVGEDT
                     LASIEQGRRRLKADLAELLDTILNTKRALATAVSKIPDRERYPAFAQEFVEHEQEALTL
                     LSYQNHVIPGLLQTPEYVEQIYANLFPPLSSEATEVAIRARLDRQNLLHREPPPVMNFI
                     IEESVFQRHMGNPDGMRRQIRHLRECADLPFIGIQVMLTATDAHAGLAGPLVLLETPDH
                     DHLAYAEGQHNGFLMDDPDEVSAYQQRYGMLRSQALSPQRTKSLLNTLLE"
     gene            9655..9921
                     /locus_tag="KNZ81_RS07390"
                     /old_locus_tag="KNZ81_07390"
     CDS             9655..9921
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893458.1"
                     /locus_tag="KNZ81_RS07390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07390"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_215222199.1"
                     /transl_table=11
                     /translation="MTSEAPSVRNLGWFKSSYSSNAGGDCVEVAYNWRKSSYSGDFQDA
                     CVEVAAHPTTVHVRDSKVPAGPVLDVTPTAWAAFVHATAGPLV"
     gene            10001..12286
                     /locus_tag="KNZ81_RS07395"
                     /old_locus_tag="KNZ81_07395"
     CDS             10001..12286
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414954.1"
                     /locus_tag="KNZ81_RS07395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07395"
                     /product="terpene synthase family protein"
                     /protein_id="WP_252922910.1"
                     /sec_met_domain="T1TS (E-value: 2.1e-81, bitscore: 273.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFVLPDFYVPYPARLNPHLEEARAHARVWADEMGMLEGSGIW
                     DLADLEAHDYALLCAYTHPDCDGPALSLVTDWYVWVFFFDDHFLELFKRTQDREGAKAY
                     LERLPAFMPMDLADGFPEPQNPVEAGLADLWARTVPAMSEDWRRRFALSTENLLNESMW
                     ELSNINAGRVSNPLEYIEMRRKVGGAPWSAGLIEYAAQAEVPEAVAYSRPLRVLTDAFS
                     DGVHLRNDLFSYQREVEEEGELSNGVLVLERFLECTTQEAAEAVNDLLTSRLQQFENTA
                     LTELGPLFADKGLNPAESASVLAYVKGLQDWQSGGHEWHMRSSRYMNEGAVDGEAAPPT
                     PGGSPGALAAALLGGTLGTSALNVGAFFGRPARQRARSFSHVPYQRTGASLLPDFKLPF
                     PTRLSPALEQSRVDTVEWAHRMGLLVPQPGVPGSDVWDEEALAGYDFPLCAAGLHPEAD
                     LEELNLASEWLTWGTYGDDYYPAVFGRTRNFAGAKLCTDRLRDFMPVEQPSAGPVPTSA
                     LERSLADLWVRTASAMPEKARREFRKTIEVMLDSWVWELDNQAIGRIPDPIDYMEMRRA
                     TFGSDLTMSLCRLRHGNIVPEEVYRSGTIQAMEKAVSDYGALINDVFSYQKEVEFEGEI
                     HNAVLVTQNFFDCDYPTGLAYVDALMNARLEQFEHIVAHELPVLYEDFQLDGAARKVLD
                     GYVRQLENWLSAILTWHRGCKRYKEEDLSHHSPGVRRVIEAAPRGIGPNGLGASTLGTA
                     AARVFAGG"
     gene            complement(12322..13695)
                     /locus_tag="KNZ81_RS07400"
                     /old_locus_tag="KNZ81_07400"
     CDS             complement(12322..13695)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642015.1"
                     /locus_tag="KNZ81_RS07400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07400"
                     /product="heme exporter protein CcmD"
                     /protein_id="WP_033946845.1"
                     /transl_table=11
                     /translation="MLGAAGATAAPAVAAPDQGRPAAVAPVRAAPQAPAAATVSEVAKA
                     WRDGPVFVDPDVSDQLSDADARDLSQEIQDSDKAIFVAVLPATFTDDVDQTMNDLRGDT
                     GITGLYVLRIGDDLHVRADESVLSRQAVQNLESRFQDTTPAAEQLTGLVGNATQNMGGR
                     APTSWSSQDSVSGATWLGLGIAVVVVGGAAYTLTRRRKIRREQAQQEALAKLRVVVDED
                     ITAFGEELERLDFRPLEPGATDEMRGDYERGLDAYENAKSLMDHAQKPEDVREVTKALE
                     DGRFALAVLDARRSGRELPVRRPPCFFDPRHGLSAADVTWAPPGGAPREVPVCAADQAR
                     LERGEDPDIRTVESDAGGRRPYWEAGPAYGPWAGGYFGGGILPGILVGTMLGHMMMSPA
                     YAADYGSAEGFGDGGAGGGYEGGDASGSDFDPGDFGGGGGFGDGGGFGGGGGDFGGGF"
     gene            complement(13854..15623)
                     /gene="cimA"
                     /locus_tag="KNZ81_RS07405"
                     /old_locus_tag="KNZ81_07405"
     CDS             complement(13854..15623)
                     /EC_number="2.3.3.21"
                     /GO_function="GO:0043714 - (R)-citramalate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046912 - acyltransferase activity, acyl
                     groups converted into alkyl on transfer [Evidence IEA]"
                     /GO_process="GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cimA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470910.1"
                     /locus_tag="KNZ81_RS07405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07405"
                     /product="citramalate synthase"
                     /protein_id="WP_251681875.1"
                     /sec_met_domain="HMGL-like (E-value: 3.2e-44, bitscore:
                     150.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQATPEEPAERAPSAATKPQVARDVRGGDGARPATAGTPASAT
                     SSAAVDAAVERPLHIFDTTLRDGAQREGINLSVADKLTIARHLDDFGVGFIEGGWPGAN
                     PRDTEFFARAREEITFRHAQLVAFGATRRAGGSAADDLQVKALLDSGAPVVTLVAKAHD
                     RHVELALRTTLDENLEMVRDTVSHLRAQGRRVFVDCEHFFDGYAANPAYAKAVVRTASE
                     AGADVVVLCDTNGGMLPAQIQAVTATVLADTGARLGIHAQDDTGCAVANTLAAVDAGAT
                     HVQCTANGYGERVGNANLFPVVAALELKYGRTVLPEGALAEMTRISHAIAEVVNLTPST
                     HQPYVGVSAFAHKAGLHASAIKVDPDLYQHIDPELVGNRIRMLVSDMAGRASVELKGKE
                     LGIDLGDDRALVGRVVERVKERELAGYSYEAADASFELLLRDELRRGTDGAGDAAPSRF
                     FRVESWRAITENRPDGIHANEATVKLWAKGERLLATAEGNGPVNALDRALRVALERIYP
                     ELAKFALRDYKVRILEGRSGTDSTTRVLISTGDGDAEWSTVGVAENVIAASWHALADAY
                     TYGLLRAGVEPAE"
     gene            complement(15985..16110)
                     /locus_tag="KNZ81_RS07410"
     CDS             complement(15985..16110)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KNZ81_RS07410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_256445227.1"
                     /transl_table=11
                     /translation="MAEWFDWSVYASFATYYAGSFFPGGNPTAQLMNTLGIFAVG"
     gene            complement(16169..17248)
                     /locus_tag="KNZ81_RS07415"
                     /old_locus_tag="KNZ81_07410"
     CDS             complement(16169..17248)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414969.1"
                     /locus_tag="KNZ81_RS07415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07410"
                     /product="agmatine/peptidylarginine deiminase"
                     /protein_id="WP_215222200.1"
                     /transl_table=11
                     /translation="MPDAPAPSLRGTVPPGFRMPPEWAPHLRTWMAWPGPNPTFATETA
                     LASAEHAWAEVARTVRRFEPVTVLAGPGRAEGARALLGPGVDVLERPLDDAWMRDIGPT
                     FVTRADDGTRAALDWTFNGWGAQEWARWEHDAKIGGEVAALAGVTAYRTGLVNEGGGLH
                     VDGEGTVLLTETVQLDPDRNPGLSRAEVEAEIHAGLGTSKAVWLPRGLTGDYGRFGTRG
                     HVDIVAAFARPGVVVAHTQPDPAHPDHEVCKEITGVLRAARDAAGRPLEVVEVPAPTVL
                     EVDGEWADYSYINHYLCNGGVVLCAFDDPRDAEAAALFRRLFPDRTVVPVDARPVFAAG
                     GGIHCITQQEPAPARGARG"
     gene            complement(17257..19059)
                     /locus_tag="KNZ81_RS07420"
                     /old_locus_tag="KNZ81_07415"
     CDS             complement(17257..19059)
                     /EC_number="3.5.1.5"
                     /GO_function="GO:0009039 - urease activity [Evidence IEA]"
                     /GO_process="GO:0043419 - urea catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470907.1"
                     /locus_tag="KNZ81_RS07420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07415"
                     /product="urease subunit alpha"
                     /protein_id="WP_215222201.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.3e-45, bitscore:
                     154.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDPTDRALPGGLTPRPRAFPHPARTPHGRRTAPDEAARGSDPYA
                     YAAVHGPRTGDRVRLGDTGLTVRVEADAQRPGDEFLAGFGKTARDGLHLRAAAVRDTCD
                     LVISNVLVIDAVLGIRKVSIGVREGRIHAVGRAGNPDTLDGVDVVVGTGTTIVSGEGLI
                     ATAGAIDTHVHLLSPRVMEASLASGVTTIIGQEFGPVWGVGVNSPWALRHAFAAFDAWP
                     VNIGFLARGSSSHAAPLVEALAEGGACGFKVHEDMGAHSRALDTALRVAEEYDVQVALH
                     SDGLNECLSVEDTLQVLDGRTIHAFHIEGCGGGHVPNVLRMAGVPHVIGSSTNPTLPFG
                     RDAVAEHHGMIVSVHDLKPELPGDAAMARDRIRESTMGAEDVLHDLGAIGITSSDAQGM
                     GRAGETIRRTLQLAAKMKRERGPLDGDGEGDDNARVLRYLAKLTVNPARAHGLSHEVGS
                     LEPGKLADIVLWRPEYFGAKPQLVLKSGFPAYGVTGDPNAATDTSEPLVLGPQFGAHGA
                     AAAELSVAFVAGAAVGLGADALPTRRRRVPVRGTRNIGPADLLLNSRTGQVDVDARTGL
                     VTLDGHPVRSGPADSVSLNRLYFL"
     gene            complement(19056..19811)
                     /gene="ureA"
                     /locus_tag="KNZ81_RS07425"
                     /old_locus_tag="KNZ81_07420"
     CDS             complement(19056..19811)
                     /EC_number="3.5.1.5"
                     /GO_function="GO:0009039 - urease activity [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019627 - urea metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ureA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642020.1"
                     /locus_tag="KNZ81_RS07425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07420"
                     /product="urease subunit gamma"
                     /protein_id="WP_215222202.1"
                     /transl_table=11
                     /translation="MRLTPTERDRLLIFDAAQLARARQARGLRLNVPEATALIADTVCE
                     AARDGARLAEAVAVGRAVLGPDDVLPGVADVLTEIQVEAVFEDGTRLAVLAHPIGGGHT
                     GDQAPGALLPGTPHAGPGPVLALRVTNTATVPVSVTSHFHFFEANPRLSFDRAAAYGMR
                     LAVPAGSSLRFGPGETREAGLVPIGGARVVIGFAGLVDGPLDAPGARAEALRRAAACGY
                     LGAGAPGAEPAPPGATPALPGTPAPETDA"
     gene            complement(20135..21223)
                     /locus_tag="KNZ81_RS07430"
                     /old_locus_tag="KNZ81_07425"
     CDS             complement(20135..21223)
                     /EC_number="2.6.1.42"
                     /GO_function="GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_4 (90-343). E-value: 2.6e-28.
                     Score: 91.3. Matches aSDomain:
                     nrpspksdomains_KNZ81_RS07430_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657639.1"
                     /locus_tag="KNZ81_RS07430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KNZ81_07425"
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="WP_023416841.1"
                     /transl_table=11
                     /translation="MTTPTIELKPSAHPLPEAEREAILARPGFGRHFTDHMVTVKWTEG
                     RGWHDGQLVPYGPLSLDPATNVLHYAQEIFEGLKAYRRPDGSVASFRPDANARRFQASA
                     RRLAMPELPVETFIEACDLLVAQDKAWVPPHGGEESLYLRPFMIATEVGLGVRPANEYL
                     FVVIASPAGAYFPGGVKPVSIWLSENRVRAVPGGVGDAKTGGNYAASLLAQAEAAAEGC
                     DQVAYLDAVEHKWVEELGGMNLCFVYGDRLVTPTLTGSLLAGVTRDTLLSLAADLGYRA
                     EEGRVSIDQWREDSRSGALTEVFACGTAAVITPVGRVKTATDEWSQGTGEPGEVTLRLR
                     EALLALQTGRAEDRHGWMHPLG"
     aSDomain        complement(20195..20953)
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KNZ81_RS07430_Aminotran_4.1"
                     /evalue="2.60E-28"
                     /label="KNZ81_RS07430_Aminotran_4.1"
                     /locus_tag="KNZ81_RS07430"
                     /protein_end="343"
                     /protein_start="90"
                     /score="91.3"
                     /tool="antismash"
                     /translation="FRPDANARRFQASARRLAMPELPVETFIEACDLLVAQDKAWVPPH
                     GGEESLYLRPFMIATEVGLGVRPANEYLFVVIASPAGAYFPGGVKPVSIWLSENRVRAV
                     PGGVGDAKTGGNYAASLLAQAEAAAEGCDQVAYLDAVEHKWVEELGGMNLCFVYGDRLV
                     TPTLTGSLLAGVTRDTLLSLAADLGYRAEEGRVSIDQWREDSRSGALTEVFACGTAAVI
                     TPVGRVKTATDEWSQGTGEPGEVTLRLREAL"
ORIGIN
        1 cctccccttc gtcatcgccc tcaacggctt cgacggacac cagccctacg cccccgaaga
       61 agtacgcgaa gcactccaga tcggccccga cgcccccatc atcaccaccg acgcacgcca
      121 ccgcgccgac gccaaaagcg cactcatcac cctggtcgag cacgcactga tggcccggct
      181 gcgctagcgg taccgggccc cggacacgcc gacggccccc gcccttcccg gagttctccg
      241 gaggggacgg gggccgtcgg ggtgttcggg gtgcgccgcg cggggcggcg cggggctcag
      301 ccctgccagc tgtgcggggc gcggaagccg ggggtgcgct ccaggcggcg ccagccggcc
      361 cggtcgcggc cgcgacgcgc ggccggggcg ggctgcgcgg cggcgcgggc catcaggagg
      421 gcggtgatcg ccgccagttc ctcgggctcg gcgtggccct tctcgacccg caggaactgc
      481 tcgggagtgg ccggaacggt gggtgtggcc atggggatgc ttctccgtgt tctggtgagt
      541 ccggtcgccg tcactggggc gggttgccgt gcttgcggga gggcaggtcg gcgtgtttgg
      601 tgcggagcat ggccagggag tcgatgagga cctggcgggt ctcggcgggg tcgatgacgt
      661 cgtcgaccag gccgcgttcg gcggcgtagt aggggtgcat cagctcggcc ttgtactcct
      721 tgaccatgcg cgcgcgcatc gcctcggggt cgtcggcgcc ggcgatctgg cggcggaaga
      781 tgacgttggc cgcgccctcg gcgcccatca cggcgatctc gttggtgggc caggcgtagg
      841 tgaggtcggc gccgatggac tgggagtcca tgacgatgta ggcgccgccg tacgccttgc
      901 gcaggatcag cgagatccgg ggcacggtgg cgttgcagta cgcgtagagg agtttggcgc
      961 cgtggcggat gatgccgccg tgctcctggt cgacgccggg caggaagccg gggacgtcca
     1021 ggagggtgac gatcgggata ttgaaggcgt cgcacatctg cacgaaccgt gcggccttct
     1081 cggaggcctc gatgtccagg actccggcga gggactgggg ctggttggcg acgatgccga
     1141 cgacctggcc gtccaggcgg gccagggcgc agatgatgtt gcgggcccag cgttcgtgga
     1201 cctccaggta gtcgccgtcg tcgaccagct cctcgatgac cttggccatg tcgtaggggc
     1261 ggttgccgtc ggccgggacg aggtccagga gggcgtcgcc gcgccggccg gccgggtcgg
     1321 tggcctcggc ggcgggcggg ttctcccggt tgttctgcgg gaggagggag aggaggtagc
     1381 ggacctcggc gaggcaggtc tcctcgtcgt cgtaggcgaa gtggcagacg ccggaggtct
     1441 cggcgtgcac gtccgcgccg cccagaccgt tctggctgat ctcctcaccg gtgacggcgc
     1501 gcacgacgtc gggtccggtg atgaacatct gcgaggtctc gcggaccatg aagacgaagt
     1561 cggtcagcgc cgggctgtag gccgcgccgc ccgcgcacgg gccgagcatc acgctgatct
     1621 gcgggatgac cccggacgcc ttcgtgttgc gctggaagat cccgccgtac ccggccagcg
     1681 ccgagacgcc ctcctggata cgggcgccgg cgccgtcgtt gagggagacc agcggggcac
     1741 cggccgcaat cgccatgtcc atgatcttgt ggatcttggt ggcgtgggcc tcgcccagcg
     1801 caccgccgaa gatccggaag tcgtgcgcgt agacgaagac cgtccggccc tcgaccgtgc
     1861 cccagccggt gatcacaccg tcggtgtggg gcctcttctg ctccaggccg aaaccggtcg
     1921 cccggtgccg gcgcaactgc tcgacctccc ggaacgaacc ctcgtccagc agcagggcga
     1981 tccgctcacg agcggtcagc ttccccttgg cgtgctgcgc cgccgtggcc ttctcacccg
     2041 gaccctgctc ggcccgctgg cgcagggcgt ggagttcggc cacgcggcca cgggcgtcgg
     2101 cgggctcgct cccggactca gctgtctcgt ccaaaacggt catgtagcga ctctacgaac
     2161 ccgggccccg agaacctgcc gtcgactcct cacagtctcc gggccgtttt cctggagcgg
     2221 tctcacaggc ggattggggt acgcagcgca ttcgactgcc gggagggggt gcgcgttatg
     2281 gggttccgac aaaagccggt gggtcgcggt cctctctccc acccgtaggg accccacaag
     2341 cggctgcgcc cggacgaggg gcgccgcacg gcacgggtcc gtccgccgag ggtagcggcg
     2401 gacggacccg ggaggaaaac gggggcggcg gggggcggtc agcagccgcc gcagttgtag
     2461 taggtcacgt cccagtggtt gccctcgttg gcgtagacgt tgccggagcc cgactggtac
     2521 tgggcggcac cgtcgccgcg ctggccgatg taggtgaagg tgccggtgac gtagttgttc
     2581 aggcaggtgc tcttggagaa gtcgagcttg tagccgttcc agtgcgagta ggtgccgccg
     2641 gcgtggccgg tctcggtgcc gccggtgatg ttgatggcgc agccgctcgc cgacttcagg
     2701 gtctgggcgc cctgggcggt ggcgagattc agctggtcga aggaggtaca ggtcgagacg
     2761 ttgcggttgg agcacccccc ggaggaggac caggtgatgc cggaggagga gaaccgcgag
     2821 gtggcctggg cgtgggtgat cttggtggcg gccgcgccgg cctcggcggt ggtggaggtg
     2881 ggagccggtg cggcggtggc ggccgtggcg gtgccgatga caccgaaccc ggctccggcg
     2941 acgagggcga gggcgctcag cgccgagcgg atcttcatgg aggtcctcct tgcggggcgc
     3001 gtgcggcgca cgcggcggtg ggggtgcgtg ggggtggtgc ggaggccgtg cggggcgggg
     3061 cagacgcata gtgcccgagt tctacgcggg tcaccagagg acctcaccga tcagttccgg
     3121 ccaactaggg ggcgcgttcg gcgcgcgtgc atccgccgga gggccgccac cgaaggcgat
     3181 ccgacggaag atgttgaaag ttgaaccgaa acgcgttacc ttcgaactcg ttgaaacttc
     3241 aacatctcct ccctgctccg gagaccgtcc ggagcacgtc cccaaggagc acctcatggg
     3301 catcttcggc cgcaagaacg agaccaccga caccaccgtc agccccgacc tggccgcgct
     3361 gaccggcacg tacacgctcg acccgacgca caccacgatc ggcttcgtgg cgcggcacgc
     3421 catggtcacc aacgtcaagg gcggcttcgg cgacttcacc ggcacgctga cgctggacgg
     3481 ctccgacccg tcgaactcca ccgcggagat cgacgtggcc atggactccg tcgacaccgg
     3541 caacgcggac cgcgacggtc acctgaagaa cgccgacttc ttcaagaccg acgagttccc
     3601 gaagatgacc ttccgctcga ccgaggcgga ggcgctcggc ggcgacgact accggatcac
     3661 cggagacctg accatcctcg gcaccacccg cccgctctcc atcgacctgg agttcaacgg
     3721 ctccgccacg gacccgttcg gcaacgagcg cgtcggcttc gagggcaccg cctcgatcct
     3781 ccgctccgaa tggggcctga cctggaacgc ggcgctggag accggcggcg tcctcgtctc
     3841 cgacaagatc aagctggtct tcgacatctc ggcgatcaag aacgcctgac gcggaccggc
     3901 ccccaggggc accggggccc gagagcccta ccgagcgcgc ccgccctccc ttccggaggg
     3961 cgggcgctcc tgcgtgcggg cccgcctgcc ccaccgtgct ggtcggctcc gacggctacc
     4021 cggtggcgct atgcaccccg gtcctcggcc aggtgccgac cgtgcgcctc ctgatgggcg
     4081 gtgcaggaac gaccattcgg tggccgccgt gaatgcgccg gtcactcccc ccgcacgccc
     4141 cgcacgttcg ggtgacgccg agggtggcgc gggtggggcc gggtagctga cggtcggagc
     4201 cgaagggtgg gcgcgtaggt gtgcgggcgg agcggatgcc gctcgcgcac cccggccgac
     4261 gcgccctctg ctgacccctc ggcgccaccc tccgccctct cctcaccgct caccgccggg
     4321 gtcgtctccc cgctccggcc gggggtggtc ggagggggcg gttcaggggg agacgcggta
     4381 gcccggcacc gagggccagc gcacggtcat cacgacggac ggctcctcgg cctcccagga
     4441 gtggtcgacg cccttgcccc agatcacgta ctgcccctgc tcgctcagga ccacgtcccg
     4501 ctcggggaac tgcatccgga accgtccgct gacgaggacc agcagcgcct gccgctcctc
     4561 cccgcgcacc caggcggcgc gccgctcgcc cgcctcgtgg acgccccatt tgatctccac
     4621 ggcctcgttg tggcgcgggt cgtccagcgc cttgaagtgg cccatgatcc agccggcgtc
     4681 cagcgcggcc tcctcggggg cgttgcccac gtacacgttc tcgctcatcc tccggacggt
     4741 agtacacgtg agggtggtct ccccggcggc ccgggggtgg ccgggcgggg gcagctttgg
     4801 ttgggtgggg tggtcctgct gacacgttgt cgtacgacag agggggttga gggacgtgag
     4861 gagcacagcg gaggtctccg tggcggccgt gatcgaggcg gagccgaagg cggtctacga
     4921 gcgggtcgcc gacgtggcgt ccatggggcg gtggagtccg gagtgtgtgc ggacggcggc
     4981 gggcgtcggg cccgcgccgg tgggcgccga gttcaagggg accaacaagg ggccgagcgg
     5041 ccggagctgg tcgacgcggt gccgggtgat ggtggcccgc tccggtgagc ggttcacctt
     5101 ccgggtgcgg ttctggggta tgccggtggc cacctgggac taccgcttcc gcccggtcgg
     5161 ggacggcacc gcgaccgagg tgaccgagac ggccgtggac cagcggaacc ggctcctgtg
     5221 gttcctcggt tcggcggtca gcggcgtctg ggaccggagc gcgcacaacg ccgagaccat
     5281 gcgggagacc ctggagcggc tgcgcgagac gctggaggcg gagcggcggg cgggttagga
     5341 cacgtccggg cggcgttgtc ggtgaggtgt ggtgggatcg gacacatgag cgatcaccag
     5401 acgacggggg ccgacgggga agaggcgcgc gcccgcgcgg cggtgcggga cgcctgggcg
     5461 cgcatcgacg cgtggatgcg cgcccacgcc ccggactcct acgaggtact ggcaccgcct
     5521 gccgacccgg cggcggtgga ggcggcccag gccgagctgg acgtgcggtt cccggcggac
     5581 ctgctcgcct ccctcgcctg ccacgacggc ctgcgccact gggccaactg cctgcccctg
     5641 cgcccaccgc tgcccgtcgc cgacatcgtc gaccactggc agatgtgcgt cgagatcgac
     5701 gaggacaacc gcgccgacga ggacgagccg gagcccgagg gcgaggagcc ctggtggcac
     5761 ccccagtgga tcccgtgggc ccagagcgac ggcgacgccc agatcatcga catgcgcccg
     5821 ggccccggcc agggccgcct cggcatggcc taccacgacg actgcggcgt cttcggcgac
     5881 ggctggccct ccctggcgac gtacctgacc gaggtcgccg acgtcctgga gaagggcggg
     5941 gcggtggggg gaacgtgggc cccctatctg acgaccgcgg gcgagctgtg gtggtccctc
     6001 aagggcgaga cccagctcaa cggcgagccg ttgacaccgg ctccggcgcc gtcggccggt
     6061 tcctgacgcc ctgccgggcg ggggctgacc gcaccggccc gatcaggtga cgcggcgcct
     6121 ccgggtccgg ccgcggttcc acgggcgggg caccgggcgt ggccggagtg tgcacgcggt
     6181 aaagcggaca ctcctgttcg cgggcgcggt tcccgcggcc cgcccgcccg gaccaccgca
     6241 gggcgacgtg gtccccgcgc gacgacctcg ctcgggaggt cgaattgccg tggtaggtcc
     6301 accgccacgt cccggactcg gtggccttca cctgctctca ccggtcctcg tcccagatcg
     6361 cggtgtcggg gtcgatgccg tgggcccgcg cggcggcgtc gacgagttgg cggaaccagg
     6421 tggcgaggcc ggggcggacg gcgtcgtagt gggcggcgaa gcccggatcg ccctcataca
     6481 tacggccgag gcagacctgc atctgacggg agagggggaa gtaggacgcg aagacctcgc
     6541 ggtggcgttc gacgaggtgg ttcgcctccg ggctgccggg ggtgacgccg gagtccatcg
     6601 cctcgccgag ggcgcgttcg agccgggcga cgtcgtcggc gacggcctgc cactcctccg
     6661 gggtgcggga ggccgagcgt tcggcgtact gccgccattg cgtcgtgtcc ccgtagcgct
     6721 gacgggcctg gaccggaccg tcggggctcc atccggggcc gaagatcgcg gcctgttgct
     6781 cggcggtcag cagcaggccg tgttcgtggg cgtcgatcat ccggtcgagt ccggcgccga
     6841 gttgctggag gcggtcgatg cgggcggcga tctgggcgcg ttgcgcgcgc agagcggccg
     6901 gtacgtccgt ggccgcgtcg tcgaggacgg cgcggatctt gtccaggccg aggccgagtt
     6961 cgcggtagac gacgatgcgg tgcaggcgtt ccaggtcggg ggcggtgtag agccggtatc
     7021 cggcgggcgt gcgcagggac ggccgggcca ggccgatctc gtcccagtgg tggagcgccc
     7081 ggaccgtcac gtccaggcgc gccgaggcct gaccgacggt caggccctcg gcgtccgggg
     7141 tgtcaggcat gccgctcatt gtcgcccggg gtctcgccgg gcggggtgat gccgatggct
     7201 tggaggttgc gtgcctcctg ggtgtccggg tcgaagggct tcgcggcggt gaagacgatc
     7261 cgcgcgttct cgggggtgat gacttccacg tcacgggtgt tccagggcgt gtcccgcggc
     7321 ccctcgaccg cgtccgggcg cagcgcacgg catgcctcga cgagggagtc gacctggctg
     7381 agcacgccgg agaaactgaa gctcatcgcc ggcggctgtt ccggaacgct ctccgccgcc
     7441 acgaggagca cgtcctggaa cgcccatcga cgcagatgca cgagggtgcc cggaatgctg
     7501 aacagctcga agaagccgag cccccgcgtc cagaactcca ccgacgccgc cagatcggtc
     7561 gtcgggatgt tcacgaaggc gggcattccg tagatgccgc ggaacggctc cggggggacc
     7621 gcgtcgggcc cgggagcggg cacggggctg atctcgaacg cgtcgtagta ggtgtcgtcg
     7681 ctcatgtgcc ccagcctcgg gcctcacgca acgtgagggt caagccggga tcgtgcgttc
     7741 tgcgcgcccg ggagaaaaga ccgggcatcc ggagcacgcc cgtgccaggc tggccgcatg
     7801 acgacctacc accgaaaggc ccgtgccgcg taagccgccg ggacgggtgc ggaccggact
     7861 cccccgcccg cgcaggccct acgagaagtc gcccgtgatc gacgggttgt cgggcgggac
     7921 gctcgccgag ctggcccggc tggagcgcac gcggaaccat ctgtggccgg gagccgtgtc
     7981 cgaggccgta cgcgcctggg ccgggcacgt gcggctgccg cgcggccgca cctggcccca
     8041 cccgggacac ggcccctgct actgctgccc cgacccgtgg gagtcccggg aactgctcga
     8101 ccaggtcgcc cgcgccctgt cccggcgcgg ggcgcgcgaa ctgcggcgcg tactggcggc
     8161 gcacgaccag ctctgggacc cggcgccccg gacgtaccgg ggcgagggcc cgtggtgagg
     8221 ccggcgcgcc ccggcggacc ctcgcggacc tcgccctgat tccggccgtc gcggctcagg
     8281 gcgacagcgg acggggctac ttccccgtgc aaccgacccc cacgggacgg aaggagcacc
     8341 agacgctctt gcccgggtcg cgctccccca ccccccagtc gtcggcgagg gcggagacca
     8401 ggagcaggcc ccggccggac tcggcctcgc cgccgggggc gcgggtcgcg gggcgcccgt
     8461 cgccactgtc gtggacctcg acgcgaacgc cgccgtcgtc ggcccggagc acgaagagcc
     8521 ggaagccccg gccgggcggg acgccgtgga gcagggcgtt ggtggccagt tcgctcacgc
     8581 agagcaagac gtcgtcgcgg cgcacgcggg cgtcccactc gtccagcacg gcggcggtga
     8641 agtccctggc tgcggggacg gatcggcgct cgcggcggta gaagcgctcg cagtgcgcgg
     8701 ggagtccggt ttcggttttc accctcctac ggtcacccaa cgtcactagc cttgtgcagg
     8761 gcgtcgaccc gtacaaatcc gttgtacggg ccgtgtcggg tgcgcgacgg ggcgcgtcgg
     8821 gagatggagt gcgtatgcag cagcggaaga agtccagcaa gaaggtcacg tcgtgggaag
     8881 tggtgggggc ccaactggcc gagtttcggc gctcggccgg actgacccag ccgcagttgg
     8941 ctggcacagc caaggtcggg gaagacacgc tcgcctcgat cgagcagggt cggcggcggc
     9001 tcaaggcgga cttggccgag ctgctggaca cgatcctcaa caccaagcgg gcgctggcaa
     9061 cggcggtgtc caagattccg gacagggagc gctacccggc tttcgcccaa gagttcgtgg
     9121 agcacgagca ggaggcgttg acgctgctct cgtatcagaa ccacgtcatt cccggccttc
     9181 ttcaaacgcc tgagtacgta gagcagatct acgccaacct ctttcctccg ctcagctctg
     9241 aagcaacgga ggtggccata cgagcacggt tggaccgcca gaacttgctg cacagggagc
     9301 cgccgcccgt gatgaacttc atcatcgaag agagcgtgtt ccagcggcac atgggaaatc
     9361 ctgatggcat gcgtcggcag atccgtcacc tacgcgaatg cgccgatctc ccgttcatcg
     9421 gcatccaggt gatgctgacc gcaacagacg cccacgcggg actggcggga cctctcgttc
     9481 ttctcgaaac gcctgaccac gaccacctcg cgtatgcgga agggcagcac aacggcttcc
     9541 tcatggatga cccggacgag gtcagtgcct atcagcagag gtatgggatg ctgcggtcgc
     9601 aggccctctc accgcagagg accaagagcc tgctgaacac actgttggag tgacatgacc
     9661 agcgaggccc cctccgtccg caacctgggc tggttcaagt ccagctacag cagcaacgca
     9721 ggcggcgact gcgtcgaggt cgcctacaac tggcgcaagt ccagctacag cggtgacttc
     9781 caggacgcct gcgtagaagt cgccgcccac cccaccaccg tccacgtccg cgactccaag
     9841 gtccccgctg gccccgtcct cgacgtgaca cctaccgcct gggcggcgtt cgtacacgcg
     9901 accgccggtc cactcgtatg acaacaccgc cgtccggctg acgggtcggg cgggcgggta
     9961 gtgatcgggc cgccggtatc accgtgtgga aggctcgacc gtgacacagc cctttgtcct
    10021 gcccgatttc tacgtgccgt acccggcgcg gctcaaccct catctggaag aggcgcgcgc
    10081 ccatgcccgg gtctgggcgg acgagatggg gatgctggag gggtcgggga tctgggacct
    10141 ggccgacctt gaggcccacg actacgcgtt gctctgcgcg tacacgcatc cggactgcga
    10201 cggtccggcg ctgtcgctgg tgaccgactg gtacgtgtgg gtcttcttct tcgacgacca
    10261 cttcctggag ctgttcaagc ggacgcagga ccgtgagggc gcgaaggcgt acctggagcg
    10321 gctgccggcg ttcatgccga tggatctggc cgacgggttc ccggaaccgc agaatccggt
    10381 ggaggcgggg ctcgccgacc tgtgggcgcg gacggtcccg gccatgtccg aggactggcg
    10441 ccgccgcttc gccctctcca cggagaacct gctcaacgag tcgatgtggg agctctccaa
    10501 catcaacgcg ggccgcgtct ccaacccgct ggagtacatc gagatgcgcc gcaaggtcgg
    10561 cggcgcgccc tggtcggcgg ggctgatcga gtacgcggcg caggccgagg tgccggaggc
    10621 ggtggcgtac tcgcggccgc tgcgcgtgct caccgacgcc ttctcggacg gcgtccacct
    10681 gcgcaacgac ctcttctcct accagcggga ggtcgaggag gagggcgagc tgagcaacgg
    10741 cgtcctcgtg ctggagcggt tcctggagtg cacgacgcag gaggcggccg aggccgtcaa
    10801 cgacctgctg acctcgcgcc tccagcagtt cgagaacacc gcgctgaccg aactggggcc
    10861 gctcttcgcc gacaaggggc tgaatccggc cgagtccgcc tcggtgctgg cgtacgtgaa
    10921 ggggctccag gactggcagt cgggcggcca cgagtggcac atgcgctcca gccggtacat
    10981 gaacgagggc gcggtcgacg gggaggccgc gccgccgacg ccgggcgggt cgccgggggc
    11041 gctggcggcg gcgctgctgg gcgggacgct gggcacgtcg gcgctgaacg tgggggcgtt
    11101 cttcgggcgt ccggcgcggc agcgggcgcg cagcttctcg cacgtgccgt accagaggac
    11161 gggggcctcg ctgctgccgg acttcaagct tccgttcccg acacggctct ccccggcgct
    11221 ggagcagtcc cgggtggaca cggtcgagtg ggcgcaccgg atggggctgc tggtgccgca
    11281 gccgggggtg cccgggtcgg acgtgtggga cgaggaggcg ctggccggct acgacttccc
    11341 gctctgcgcg gccgggctcc acccggaggc ggacctggag gagctgaacc tcgcctcgga
    11401 gtggctgacc tggggcacgt acggcgacga ctactaccct gcggtcttcg gccgtacccg
    11461 gaacttcgcc ggggccaagc tctgcaccga ccggctgcgc gatttcatgc cggtcgagca
    11521 gccgtcggcg gggccggtgc cgaccagcgc gctggagcgc tcactcgccg acctgtgggt
    11581 gcggaccgcc tccgccatgc cggagaaggc gcgccgtgag ttccgtaaga ccatcgaggt
    11641 gatgctcgac agctgggtct gggagctgga caaccaggcc atcggccgca tccccgaccc
    11701 catcgactac atggagatgc gccgggccac cttcggctcc gacctgacga tgagcctgtg
    11761 ccgcctgcgc cacggcaaca tcgtccccga ggaggtgtat cgctcgggca ccatccaggc
    11821 gatggagaag gccgtctcgg actacggcgc gctcatcaac gacgtcttct cctaccagaa
    11881 ggaggtcgag ttcgagggcg agatccacaa cgccgtcctc gtcacgcaga acttcttcga
    11941 ctgcgactac ccgaccggcc tcgcgtacgt ggacgcgctg atgaacgccc ggctggaaca
    12001 gttcgaacac atcgtggccc acgaactccc cgtgctgtac gaggatttcc agctggacgg
    12061 ggcggcccgg aaggtgctcg acggatacgt gcggcagctg gagaactggc tgtcggccat
    12121 cctgacctgg caccggggct gcaagcggta caaggaggag gatctgagcc atcactcccc
    12181 cggcgtgcgg cgggtgatcg aggccgcgcc gcgcgggatc gggccgaacg ggctcggcgc
    12241 ctcgacgctg ggcacggccg ccgcccgggt gttcgccggg gggtgacggg agcgggccgg
    12301 gggtgagcgg ctccggcggg gtcagaagcc tccgccgaag tcgccgcctc cgcccccgaa
    12361 cccgccgccg tccccgaagc cgcctccgcc gccgaagtca ccggggtcga agtcggagcc
    12421 ggaggcgtcg ccaccctcgt agccgccgcc cgcgccaccg tcgccgaacc cttcggccga
    12481 gccgtagtcg gcggcgtagg cggggctcat catcatgtgg ccgagcatgg tgccgacgag
    12541 gatgccgggg aggatgccgc cgccgaagta gccgccggcc caggggccgt acgccgggcc
    12601 ggcctcccag tacgggcgcc ggccgcccgc gtcggactcg acggtgcgga tgtcggggtc
    12661 ctcgccgcgc tccagccgtg cctggtcggc ggcgcagacg ggcacctcgc ggggcgcgcc
    12721 gccgggcggg gcccaggtga cgtcggcggc cgagaggccg tggcgcgggt cgaagaagca
    12781 cggcgggcgg cgcacgggca gctcacggcc gctgcgccgg gcgtcgagca cggcgagagc
    12841 gaaccggccg tcctccagcg ccttggtcac ctcgcgcacg tcctcgggct tctgcgcgtg
    12901 gtccatgagg gacttggcgt tctcgtaggc gtcgagaccg cgctcgtagt cgccgcgcat
    12961 ctcgtcggtg gcgcccggtt ccaggggccg gaagtcgagc cgctccagtt cctcgccgaa
    13021 cgcggtgatg tcctcgtcca ccacgacccg cagcttggcg agcgcctcct gctgggcctg
    13081 ctcgcgccgg atcttgcgcc gccgggtcag cgtgtacgcg gcgccgccca ccaccacgac
    13141 ggcgatgccg aggccgagcc aggtcgcccc ggagacgctg tcctgggagg accaggaggt
    13201 gggggcgcgg ccgcccatgt tctgggtggc gttgcccacc aggccggtga gctgttcggc
    13261 ggccggggtg gtgtcctgga agcgggattc gaggttctgc acggcctgcc gggagaggac
    13321 cgattcgtcg gcgcggacgt gcaggtcgtc accgatgcgc aggacgtaca ggccggtgat
    13381 gccggtgtcg ccgcgcaggt cgttcatggt ctggtcgacg tcgtccgtga aggtcgccgg
    13441 gaggaccgcg acgaagatcg ccttgtcgct gtcctggatc tcctgcgaga ggtcacgcgc
    13501 gtcggcgtcg gagagctggt cggagacgtc cggatccacg aagacggggc cgtcgcgcca
    13561 tgccttggcg acctcggaga cggtcgcggc ggcgggggcc tgcggcgccg cccgcacggg
    13621 tgccacggcg gcgggccggc cctggtcggg ggcggcgacg gccggcgcgg ccgtcgctcc
    13681 ggcggcgccc agcacgagaa ggggcccgga cgcgatgaga gcgccccggc gtatggactg
    13741 gcggactacg gctcgcctca tacctccacg ctaacccggg tcgcggcgat gcgccccgaa
    13801 caggcggcgg gacaggtgcg ggccccgccg ccccgggcgt gcgcgcgtcg ggcctactcg
    13861 gcgggctcga ccccggcgcg gagcaggccg taggtgtagg cgtccgccag ggcgtgccag
    13921 gaggcggcga tgacgttctc ggcgacgccg accgtcgacc actccgcgtc gccgtcaccg
    13981 gtggagatca ggacgcgggt ggtggagtcg gtgccggagc ggccttccag gatgcggacc
    14041 ttgtagtccc gcagggcgaa cttggccagc tccgggtaga tccgctccag ggcgacgcgc
    14101 agggcgcggt ccagggcgtt gacggggccg ttgccctcgg cggtggcgag gaggcgttcg
    14161 cccttggccc agagcttcac ggtggcctcg ttggcgtgga tgccgtcggg gcggttctcg
    14221 gtgatcgccc gccacgactc gacgcggaag aagcgggagg gggccgcgtc gcccgcaccg
    14281 tcggtgccgc gccgcagctc gtcacggagc agcagctcga aggaggcgtc ggcggcctcg
    14341 taggagtacc cggccagctc gcgttccttg acgcgctcca cgacgcggcc gaccagggcg
    14401 cggtcgtcgc cgaggtcgat gcccagctcc ttgcccttca gctcgacgga ggcgcggccg
    14461 gccatgtcgg agacgagcat ccggatgcgg ttgccgacca gctccgggtc gatgtgctgg
    14521 tacaggtcgg ggtcgacctt gatcgcggag gcgtggagtc cggccttgtg ggcgaaggcg
    14581 gagacgccga cgtagggctg gtgggtggag ggggtgaggt tgacgacctc ggcgatggcg
    14641 tgcgagatgc gggtcatctc ggcgagcgcg ccttcgggca gcacggtgcg gccgtacttc
    14701 agctccaggg cggcgacgac ggggaagagg ttggcgttgc cgacgcgctc gccgtagccg
    14761 ttggcggtgc actggacgtg ggtggcgccg gcgtcgacgg cggcgagggt gttggcgacg
    14821 gcgcagccgg tgtcgtcctg ggcgtggatg ccgaggcggg cgccggtgtc ggcgaggacg
    14881 gtggcggtga cggcctggat ctgcgcgggc agcatgccgc cgttggtgtc gcagaggacg
    14941 acgacgtcgg caccggcctc gctcgccgtg cggacgacgg ccttggcgta ggccgggttg
    15001 gcggcgtacc cgtcgaagaa gtgctcgcag tcgacgaaga cccggcggcc ctgggcgcgc
    15061 aggtgggaga cggtgtcgcg gaccatctcc aggttctcgt ccagggtggt gcgcagggcc
    15121 agctcgacgt ggcggtcgtg ggccttggcg accagcgtga cgaccggggc gccggagtcg
    15181 aggagcgcct tgacctggag gtcgtcggcg gcgctgccgc cggcccggcg ggtggcgccg
    15241 aaggcgacga gctgcgcgtg gcggaaggtg atctcctcgc gggcgcgggc gaagaactcg
    15301 gtgtcccgcg ggttggcgcc gggccagccg ccctcgatga agcccacccc gaagtcgtcc
    15361 aggtgccggg cgatggtcag cttgtcggcg acgctgaggt tgatgccctc acgctgcgcg
    15421 ccgtcgcgga gcgtggtgtc gaagatgtgc agggggcgct cgacggcggc gtccacggcg
    15481 gcggaggacg tcgcggaggc gggggttccg gcggttgcgg ggcgcgcccc gtcgccgccc
    15541 cgtacgtcgc gtgcgacctg cggtttcgtc gcggccgacg gggcgcgctc agcgggttcc
    15601 tcgggggtgg cctggctggt catgcggtgg tgactcctgt cgggtgagtg gctccggaat
    15661 gcttggctcc acttgccccc atcctctcgt gcgcctcgcc gcggcccggt cggggccgac
    15721 aaacgaaaag acccctcgcg ggtgcgagag gtctgcgcgc gggtctgggg cacggtggcc
    15781 gcgtcgcacg tggtggtgcg gggcggtcac tgcggaccgg cgcgcctgct gccgataatc
    15841 atggcgaacg tgggcacggg ggcagtcttc cacagagacg cctccgtgcc accgggtgtc
    15901 tcaggatgcg agcggggcgt ccgttttcgc gggcggggag gccggggagg cggggccggc
    15961 ctgggcgggg gaagggttcg gccttcagcc gacggcgaag atgcccaagg tgttcatgag
    16021 ctgggcggtc gggttgccgc cggggaagaa ggaacccgcg tagtacgtgg cgaagctcgc
    16081 gtacacggac cagtcgaacc actcggccat gttgccggcc gagccggccc aggtgctttg
    16141 cggtcgtggg gcggggacgc cgggcggctc agccccgtgc gccccgggcc ggcgccggtt
    16201 cctgctgggt gatgcagtgg atgccgccgc cggcggcgaa gaccgggcgg gcgtcgacgg
    16261 ggacgacggt gcggtccggg aagaggcggc ggaagagcgc ggcggcctcg gcgtcgcgcg
    16321 ggtcgtcgaa ggcgcagagg acgaccccgc cgttgcagag gtagtgattg atgtacgagt
    16381 agtcggccca ctccccgtcc acctccagca cggtgggcgc gggcacctcg accacctcca
    16441 gcggccggcc cgccgcgtcc cgggcggcgc gcagcacacc ggtgatctcc ttgcagacct
    16501 cgtggtcggg gtgggccggg tcgggctggg tgtgcgccac gaccacgccg ggccgcgcga
    16561 acgccgcgac gatgtcgacg tgcccgcgcg tcccgaaccg cccgtagtca ccggtcagcc
    16621 cgcgcggcag ccacaccgcc ttgctggttc cgagcccggc gtggatctcg gcctcgacct
    16681 cggcacggct caggccgggg ttgcggtccg ggtcgagctg gacggtctcg gtgagcagca
    16741 cggtcccctc cccgtcgacg tgcagcccgc cgccttcgtt gaccagcccc gtccggtacg
    16801 ccgtgacccc ggccagcgcg gccacctcgc cgccgatctt cgcgtcgtgc tcccagcggg
    16861 cccactcctg cgcgccccag ccgttgaacg tccagtcgag cgcggcccgg gtgccgtcgt
    16921 ccgcacgggt gacgaaggtg gggccgatgt ccctcatcca ggcgtcgtcc agcgggcgtt
    16981 cgagcacgtc gacgccgggc ccgaggagcg cgcgggcgcc ttcggcccgg ccgggtccgg
    17041 cgaggacggt gaccggttcg aagcggcgta cggtgcgggc cacctcggcc caggcgtgtt
    17101 cggccgaggc cagtgcggtc tcggtggcga aggtggggtt ggggccgggc caggccatcc
    17161 aggtgcgcag gtgcggggcc cactcgggcg gcatgcggaa gcccggcggg acggtgccgc
    17221 gcagggacgg ggcgggggcg tcgggcatgg cggtcctcag aggaagtaga ggcggttgag
    17281 gctgacggag tcggcggggc cggagcggac cgggtgaccg tcgagggtga cgaggccggt
    17341 gcgggcgtcc acgtcgacct ggccggtgcg ggagttgagg aggagatcgg cggggccgat
    17401 gttccgggtg ccgcgcacgg ggacgcggcg cctgcgggtg ggcagggcgt cggcgccgag
    17461 gcccacggcg gcgcccgcga cgaaggcgac ggacagctcg gcagcggccg ccccgtgcgc
    17521 gccgaactgg ggtccgagga cgagtggttc gctggtgtcg gtggcggcgt tggggtcgcc
    17581 ggtgacgccg taggcgggga agccggactt caggaccagt tggggcttgg cgccgaagta
    17641 ctcggggcgc cacagcacga tgtccgccag cttgccgggc tccagcgagc cgacctcgtg
    17701 ggagagaccg tgcgcgcggg ccgggttgac ggtcagcttg gcgaggtagc gcaggacgcg
    17761 ggcgttgtcg tcgccctcgc cgtcgccgtc cagcgggccg cgttcgcgct tcatcttggc
    17821 ggcgagctgg agggtgcggc ggatcgtctc gccggcccgc cccatcccct gggcgtcgga
    17881 ggaggtgatg ccgatggcgc ccaggtcgtg caggacgtcc tcggcgccca tcgtcgactc
    17941 gcggatgcgg tcgcgggcca tcgcggcgtc gccgggcagc tcgggcttga ggtcgtggac
    18001 cgagacgatc atgccgtggt gctcggcgac ggcgtcccgg ccgaagggca gcgtggggtt
    18061 ggtggaggag ccgatgacgt ggggcacgcc cgccatgcgc agcacgttcg ggacgtggcc
    18121 gccgccgcac ccctcgatgt ggaaggcgtg gatggtgcgg ccgtcgagca cctggagggt
    18181 gtcctcgacg gagaggcatt cgttgaggcc gtcgctgtgc agggccacct gcacgtcgta
    18241 ctcctcggcg acgcgcagcg cggtgtccag cgcccggctg tgcgccccca tgtcctcgtg
    18301 caccttgaac ccgcacgccc cgccctccgc cagcgcctcg accagcggcg cggcgtgcga
    18361 ggaggaaccc cgggcgagga aaccgatgtt gaccggccag gcgtcgaagg cggcgaaggc
    18421 gtgccgcagg gcccacggcg agttgacgcc gacgccccag acggggccga actcctggcc
    18481 gatgattgtg gtcacgccgg aggcgaggga ggcttccatg acgcggggcg agagcaggtg
    18541 cacgtgagtg tcgatcgccc cggcggtcgc gatcagcccc tcccccgaca cgatcgtggt
    18601 gccggtgccg accaccacgt cgaccccgtc aagcgtgtcc gggttccccg cgcgtccgac
    18661 ggcgtggata cggccctcgc ggacaccgat cgagactttg cggatgccga gcaccgcgtc
    18721 gatcaccagc acgttgctga tcaccaggtc gcaggtgtcg cgcacggcgg cggcccgcag
    18781 gtgcagcccg tcgcgcgcgg tcttcccgaa cccggccagg aactcgtccc ccggccgctg
    18841 cgcgtcggcc tcgacccgca ccgtcagccc cgtgtcaccg agccgcaccc tgtccccggt
    18901 gcggggcccg tggacggcgg cgtaggcgta gggatcggag cccctggccg cctcgtcggg
    18961 cgcggtacgg cggccgtgcg gggtacgggc cgggtgcggg aaggcgcggg ggcgcggagt
    19021 cagccccccg ggaagggccc ggtcggtggg gtcgctcatg cgtcggtctc cggggcgggg
    19081 gtgccgggca gggcgggggt ggcgccgggc ggggcgggct ccgccccggg cgccccggct
    19141 ccgaggtagc cgcaggcggc ggcgcggcgc agggcctcgg cgcgggcgcc gggggcatcc
    19201 agcgggccgt cgaccagccc ggcgaagccg atcacgacgc gcgccccgcc gatcggcacc
    19261 agccccgcct cgcgggtctc gccggggccg aagcggagcg aggagcctgc cgggacggcg
    19321 agccgcatgc cgtaggcggc ggcccggtcg aagctcaggc gcgggttggc ctcgaagaag
    19381 tggaagtgcg aggtgacgct gaccgggacc gtggcggtgt tggtgacccg cagggccagt
    19441 acggggcccg gcccggcgtg gggcgtgccc gggagcaggg cgcctggcgc ctggtcgccg
    19501 gtgtggccgc cgccgatggg atgggccagc acggcgagcc gggtcccgtc ctcgaaaacc
    19561 gcctcgacct ggatctcggt cagcacgtcg gcgacgcccg gcagcacgtc gtccggtccg
    19621 agcacggccc gccccaccgc caccgcctcc gccagccgcg ccccgtcccg cgccgcctcg
    19681 cagaccgtgt ccgcgatgag cgcggtcgcc tccggaacgt tcagccggag cccacgcgcc
    19741 tgccgggccc gggcgagctg ggcggcgtcg aagatcagga ggcggtcgcg ttcggtgggg
    19801 gtcaggcgca tggaggtcct ggaggggcgg gggtgggcgg gcgatggagc gtcaccctat
    19861 ctaaagcatt taggttttcc aatggatggc ggatcgcgaa gcaggcgctt gggcccgggg
    19921 ggcggccagg aggcccacag gggcgggtcc ggtaaggggc ggccccgtca cccccgtacc
    19981 tgcgagaccc ccgcgaggct gccacgccgg tgccgcccct gacccgatac ggcccgccgc
    20041 ccccgcatcc gctgcggaga cggcgggccg tcccggtcgt ccgatccgcc cggccccagg
    20101 cgctctcacg ccccgggcac cgggcccccg gacctcagcc cagcgggtgc atccacccgt
    20161 gccggtcctc cgcgcgtccc gtctggaggg cgaggagggc ctcgcggagg cggagggtga
    20221 cctcgccggg ttcgccggtg ccctggctcc actcgtcggt ggcggtcttg acccggccga
    20281 cgggggtgat gacggcggcc gtgccgcagg cgaagacctc ggtcagggcg ccgctgcggc
    20341 tgtcctcgcg ccactggtcg atggagacgc ggccctcctc ggcccggtag ccgaggtcgg
    20401 cggcgaggga gaggagggtg tcgcgggtga ccccggcgag gagggagccg gtgagggtgg
    20461 gggtgaccag gcggtcgccg tagacgaagc agaggttcat gccgcccagt tcctcgaccc
    20521 acttgtgctc gaccgcgtcg aggtaggcga cctggtcgca gccctcggcg gcggcctcgg
    20581 cctgggcgag gagggaggcg gcgtagttgc cgccggtctt ggcgtcgccc acgccgccgg
    20641 ggacggcgcg gacgcggttc tcggagagcc agatcgagac gggcttgacg ccgccgggga
    20701 agtacgcgcc ggccggggag gcgatgacca cgaaaaggta ctcgttggcc ggcctgacgc
    20761 cgagcccgac ctccgtggcg atcatgaagg gccgcaggta gagcgattcc tcgccgccgt
    20821 gcggcgggac ccacgccttg tcctgcgcca ccagcaggtc gcacgcctcg atgaaggtct
    20881 ccacgggcag ctcgggcatg gcgaggcggc gcgcggatgc ctggaagcgg cgggcgttgg
    20941 cgtcggggcg gaagctcgcc acggagccgt cggggcggcg gtacgccttg agtccctcga
    21001 agatctcctg ggcgtagtgg aggacgttgg tggcggggtc gagggagagc ggcccgtagg
    21061 ggacgagctg gccgtcgtgc cagccgcggc cctcggtcca cttcacggtg accatgtggt
    21121 cggtgaagtg ccggccgaag ccggggcggg cgaggatcgc ctcgcgctcg gcctccggga
    21181 gcgggtgcgc ggagggcttc agttcgatcg tcggcgtcgt catgagtggt gtccttcacg
    21241 tgtggtggtg acagaccgcg ctcacgcccg tacccctgag cggtgcgtgg ccggggtgct
    21301 gtctcgcact ccggtcagct gtgcaccaca cggacgtccg ggtatcgcct cattttccgc
    21361 ggccccacgt ccgattatcg cgccggaggg ggctgtgagg gaacgccgag gagtccaccg
    21421 ccccgccgaa cgtgtcacgc ggcggagcgg cagaggggtg cggggtgagc acgggccctg
    21481 ggttgtcgca cccggggccg cccatgagga agccgccggg ttgtcccgtg ggggacccgg
    21541 cggcttcggg tgtagcgcgc cgggtcagcc ggctactcgt ccggcgagcg cgtcgccgat
    21601 ggcgtcggtg gaccgcgcgg tggagtcacg ctccgccagg tcggcggaga cggcctcctc
    21661 gatgcgggcg gcctcggtct cgtagccgag gtgccgcagc aggagggcga cggagaggat
    21721 ggcggcggtc gggtcggcct tgccctgccc ggcgatgtcg ggggcggagc cgtggacggg
    21781 ctcgaacatc gacgggaagg cgcccgtcgg gttgacgttg ccggaggcgg ccaggccgat
    21841 gccgccggtg acggccgcgg cgaggtcggt gatgatgtcg ccgaagaggt tgtcggtgac
    21901 gatgacgtcg aaccgctcgg gctgggtgac gaagaagatc gtcgcggcgt cgacgtgcag
    21961 gtagtcggtg gtgacgtccg ggtactcggc ggcgaccttg tcgaaggtgt tcttccacag
    22021 gtggccggcg aagacgagca cgttgttctt gtggaccagc gtgagcttct tgcggggccg
    22081 cgcctgggcg cgggcgaagg cgtcacggac cacgcgctcc acgccgtacg ccgtgttgac
    22141 gctgacctcg gtggcgacct cggcgggggt gccggtgcgc agcgagccgc cgttgcccgt
    22201 gtaggggccc tcggtgccct cgcggaccac cacgaagtcg atctccggac ggccggccag
    22261 cggggtggcg gtgttcggga agagct
//
