LOCUS       NZ_CP101740            22466 bp    DNA     circular CON 26-NOV-2024
DEFINITION  Sphingomonas qomolangmaensis strain S5-59 chromosome, complete
            genome.
ACCESSION   NZ_CP101740
VERSION     NZ_CP101740.1
KEYWORDS    RefSeq.
SOURCE      Sphingomonas qomolangmaensis
  ORGANISM  Sphingomonas qomolangmaensis
            Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
            Sphingomonadales; Sphingomonadaceae; Sphingomonas.
REFERENCE   1  (bases 1 to 3429145)
  AUTHORS   Cui,X. and Liu,Y.
  TITLE     Sphingomonas sp. nov., a novel bacterium isolated from the north
            slope of the Mount Everest
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3429145)
  AUTHORS   Cui,X. and Liu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUL-2022) Northwest Institute of Eco-Environment and
            Resources, Chinese Academy of Sciences, Donggang West Road 320,
            Lanzhou, Gansu 730030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: unicycler v. V0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024496245.1-RS_2024_11_26
            Annotation Date                   :: 11/26/2024 03:15:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,239
            CDSs (total)                      :: 3,182
            Genes (coding)                    :: 3,157
            CDSs (with protein)               :: 3,157
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 25
            CDSs (without protein)            :: 25
            Pseudo Genes (ambiguous residues) :: 0 of 25
            Pseudo Genes (frameshifted)       :: 5 of 25
            Pseudo Genes (incomplete)         :: 21 of 25
            Pseudo Genes (internal stop)      :: 6 of 25
            Pseudo Genes (multiple problems)  :: 5 of 25
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:11:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3068031
            Orig. end                         :: 3090497
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP101740.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22466
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="5"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22466
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22466
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12466](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12466
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(552..572)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.24"
                     /tool="antismash"
     misc_feature    complement(674..689)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.44"
                     /tool="antismash"
     misc_feature    771..785
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.12"
                     /tool="antismash"
     misc_feature    complement(923..937)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 23.44"
                     /tool="antismash"
     misc_feature    complement(1541..1557)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 20.62"
                     /tool="antismash"
     misc_feature    complement(1571..1585)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.26"
                     /tool="antismash"
     gene            complement(2642..3709)
                     /locus_tag="NMP03_RS14530"
                     /old_locus_tag="NMP03_14530"
     CDS             complement(2642..3709)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016145.5"
                     /locus_tag="NMP03_RS14530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NMP03_14530"
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="WP_256506192.1"
                     /transl_table=11
                     /translation="MLTVAYNELKTAGFSRVSVALPAGWDALPPFDSYHDLNKWFFDGR
                     RSVLAHGILEASAFSHTMLVGADCIDGTYNPGSITRRMVLLDEHARIGGDARILGSSFS
                     TKPHAEAIRTLRHLASNVCINARDPVSRERLQAAAGRVVRQTADLAFLTMPAGDDAIPD
                     DTRNFLEAQAAAKRPMIGLNINANIDRTVVGYTSAHDNFLRRLLGEGYSVLLVPHDNRG
                     QRSDETLLSELQLRLDPDSAKHVHLLNAHEPSFVRQVLSKLEAIVTGRMHAAILAMSAG
                     TPAISFVYQGKFEGLYQLIGLTEESVLYDPKNFAERPDEIQDQILEALGRREELRVIIH
                     RELPRVMGLARSNFD"
     misc_feature    complement(3518..3520)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    4098..4112
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.88"
                     /tool="antismash"
     gene            4167..5651
                     /locus_tag="NMP03_RS14535"
                     /old_locus_tag="NMP03_14535"
     CDS             4167..5651
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024832.5"
                     /locus_tag="NMP03_RS14535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NMP03_14535"
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="WP_256506193.1"
                     /sec_met_domain="Polysacc_synt (E-value: 4.2e-37, bitscore:
                     125.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDPPSPKPLQLGRLALQGGLVTGLAQALKMALSLVSVVVLARLL
                     APQDFGLVASIAPIVAFIALFQDLGLQAAIIQRETITREHLNQTFWISPAIASVAALLI
                     IAAAPLAALFYNDQRVTAIMVVAAVPIFIGSLATLPLSLLNRNMRFGNLALNDVLVAAT
                     GFGATVGAALLGSGYWSLVIGPIAAALTAVIAAWIASPWRPGRPTLKLDGDLWSFGANL
                     TGFNIVNFLARNFDNVLIGRVSGMTQLGLYDRSYKLLLFPLQNISQPLSRVMIPILSRV
                     QNDKARFRKIYLQTNMVLGFCLIPGIAAATLASDQLINLLFGPEWSAAAPIFAWLGIAS
                     LAQVVLVTNGWIFICQGKTRAMFRLGLWTSGVTVIAFLVGIQWGVVGLAAAYTISAYLF
                     RIPALIAVLHRIGPVTASDMSGLLLVHLLPAALSAAIIWAANLEAWELSDVVSIGICVV
                     LNYCLATLSVAIFPPARSAMVEVVGRLANLRRRQVV"
     misc_feature    5265..5267
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    5460..5462
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6052..6735)
                     /locus_tag="NMP03_RS14540"
                     /old_locus_tag="NMP03_14540"
     CDS             complement(6052..6735)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NMP03_RS14540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NMP03_14540"
                     /product="hypothetical protein"
                     /protein_id="WP_256506194.1"
                     /transl_table=11
                     /translation="MFLRLVSGFIFLSNSSRRDFIAAYPNFESAPHLITRHGRYPDGTD
                     APSPRRLVSRDIRLLMFGLIREYKNVIGLIQAFHAANDPDITLTIVGTCFDPGLRDRIE
                     LASNGSNRINLDLRSDLLTDSELNAIIDAHDGVVLPYTKILNSGVALHAIGRNKPILAP
                     AIGSLPELEQSLGQDWVSLFKPPFDQNAVRLFANHLRAGGPERADLSAYDWNTIGAEIA
                     HFIMS"
     misc_feature    complement(6421..6423)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6700..6702)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6773..6787)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.86"
                     /tool="antismash"
     misc_feature    complement(6882..6902)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.78"
                     /tool="antismash"
     misc_feature    6892..6908
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.86"
                     /tool="antismash"
     gene            7374..>8062
                     /locus_tag="NMP03_RS16230"
                     /pseudo=""
     CDS             7374..>8062
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611663.1"
                     /locus_tag="NMP03_RS16230"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLDKVRAVARGDDRRVISRIIHVADRAGAGLMNPPTTVREGRSTT
                     R"
     gene            complement(8368..9438)
                     /locus_tag="NMP03_RS14550"
                     /old_locus_tag="NMP03_14550"
     CDS             complement(8368..9438)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF026257.5"
                     /locus_tag="NMP03_RS14550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NMP03_14550"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_256506196.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 2.4e-27, bitscore:
                     93.6, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNALCADKVPLQSSLDLLRWLGNGLTPAGEIPAVADWGSVLAAA
                     TATKTIGLLGRVAGDPAAGVPAIVAEQIVSARRDILLTNLRNFDWTIKTVNALQAGGID
                     PIVFKGALRSHHVYATWDARRSSDIDLLVRPEEYCHAQQILAADGMIALVSDTSIWWHR
                     CLGESPYARPDSTSPIVDLHHRVQQPGGPYPRQMEEFFAASMVQNIGSNAIRTLSPHHA
                     LLVCAINYGKAVRARKPWLAEMHEFAWMTRSMTRDELTAVRNLAGRNNLQGLVDECLAV
                     SKLLFASSGEASADFERAALSSIGHPASVRFERTSKLWHWMDGNLLRRGGLFTIALSRI
                     ARAELALRREGLSLPK"
     misc_feature    complement(8617..8619)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(8662..8664)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9633..9648)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.76"
                     /tool="antismash"
     misc_feature    9756..9774
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.44"
                     /tool="antismash"
     gene            9787..9897
                     /locus_tag="NMP03_RS14555"
                     /old_locus_tag="NMP03_14555"
     CDS             9787..9897
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="NMP03_RS14555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NMP03_14555"
                     /product="putative RiPP precursor"
                     /protein_id="WP_256508141.1"
                     /transl_table=11
                     /translation="MELLGSFETLTKGGATGNALDAAFPTGTPFSELTFS"
     CDS_motif       9787..9822
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MELLGSFETLTK"
                     /locus_tag="NMP03_RS14555_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       9823..9897
                     /prepeptide="core"
                     /locus_tag="NMP03_RS14555_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-0.60"
                     /molecular_weight="2311.5"
                     /monoisotopic_mass="2310.1"
                     /core_sequence="GGATGNALDAAFPTGTPFSELTFS"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MELLGSFETLTK"
                     /leader_location="[9786:9822](+)"
     gene            10001..10276
                     /locus_tag="NMP03_RS14560"
                     /old_locus_tag="NMP03_14560"
     CDS             10001..10276
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.5"
                     /locus_tag="NMP03_RS14560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NMP03_14560"
                     /product="PqqD family protein"
                     /protein_id="WP_256506197.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.3e-20,
                     bitscore: 69.1, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9.5e-15, bitscore: 52.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARARYVANKDVVTCELDSGQALLNLRTSQYVKFNETAGLVWQWV
                     QDGLTVDQMADQMCTMFDAERNQCSADIALLLGQLKEAGLVELEAE"
     aSDomain        10025..10261
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_NMP03_RS14560_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.80E-22"
                     /identifier="RREFam002.1"
                     /label="NMP03_RS14560"
                     /locus_tag="NMP03_RS14560"
                     /protein_end="87"
                     /protein_start="8"
                     /score="69.1"
                     /tool="antismash"
                     /translation="NKDVVTCELDSGQALLNLRTSQYVKFNETAGLVWQWVQDGLTVDQ
                     MADQMCTMFDAERNQCSADIALLLGQLKEAGLVE"
     misc_feature    complement(10340..10358)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 24.73"
                     /tool="antismash"
     gene            10341..10685
                     /locus_tag="NMP03_RS14565"
                     /old_locus_tag="NMP03_14565"
     CDS             10341..10685
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="NMP03_RS14565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NMP03_14565"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_256506198.1"
                     /sec_met_domain="PF13471 (E-value: 5.9e-18, bitscore: 62.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIVRIGLTLGSYRLVLRWIERYARPSRRPTAVLVLVWSVRHSAK
                     LVPGASCLTQALAMRYLMLRAGEGCTIRIGVRETANRPFDAHAWVMYQGRVLIGGNEQD
                     LAAFKPLVDL"
     gene            10682..12466
                     /locus_tag="NMP03_RS14570"
                     /old_locus_tag="NMP03_14570"
     CDS             10682..12466
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="NMP03_RS14570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NMP03_14570"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_256506199.1"
                     /sec_met_domain="GATase_7 (E-value: 2.2e-13, bitscore:
                     47.8, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.2e-34, bitscore:
                     118.1, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHLMPDKSGVRVTWHDLGTEPNGLGPSLVFISPGTAIDFSAQMS
                     AELGLSVASGTEAILLAAWAKWDVAMVDRLRGDFAFGIYDPAQGVVFLGRDIFGRAPLY
                     YHLDGDGLVVAGTSRLVRAILGRSLARNEAFYADFVQGQFVEQSATFFEGLERLAPAHW
                     MKIDRGGRELYRYWSPQSVRQHTTMPDAAERFQALFDHSVARAMGGGDALVLLSGGLDS
                     SAILGSVMAANDGGLAPDCLTKTYRRTKDWVDEPYLRSLGAQYGVCPREIACDEHDPLA
                     DLDRWLDVLDGPYFSYGHSVTAHLLDIARGMGRLTLLSGHGGDEVVGYGIGRLNELAQQ
                     RQWLRLWREAPGLTALSGSSRLRVMRKYLTHYPRYRPFERLLQKQFPDTPSDEEASLSA
                     NLLAAMGENRYASQPAVNRGDHDEPTVHAEALNDVVQPLALETIGQCSRAAGVNTEMPF
                     YDRDLVELTLSLPSEWKLRDGFTRYVMRRAMEGRLPRDVLLRQDKFDFTDAFVAGLIAH
                     RHRALALTDNVDGSLDSYVNLPRLAAARAQLSRSERAITKADARFIWRCAVLAMWLKRY
                     ETSPPPPMMVPLTQGLIS"
     misc_feature    11144..11146
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    11825..11827
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    12107..12109
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    12245..12247
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    12455..12457
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12463..13383
                     /locus_tag="NMP03_RS14575"
                     /old_locus_tag="NMP03_14575"
     CDS             12463..13383
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NMP03_RS14575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NMP03_14575"
                     /product="serine kinase"
                     /protein_id="WP_256506200.1"
                     /transl_table=11
                     /translation="MNRYRAFGLLIESDFLLPELSIADSRDGPCDLRIVRADIGREIPE
                     PNAQPVFDYEDPSGTVMIWPQVAGFRFRAPDLIEVEPAPNAKSELLAFPLLGPVMGWFL
                     HLRGRMVLHASAVVWRGLAFGFLGDKLAGKSTTAAAFLRDGAQLLTDDLLVFAMDDPAV
                     PLVQPAFAQLKLGDDSAAAVTIAGAKALPLVMDGFAKRQHRLHRLAAAPAACDALFILE
                     RGDGPAVIEWLDQKDAFLGLMRFGYNVRFANAPIAMQNRQRNFEQCVALARSLRFGVLR
                     VPADLTRLDEVLEAVAESLAKPTTA"
     misc_feature    12511..12513
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13380..15107
                     /locus_tag="NMP03_RS14580"
                     /old_locus_tag="NMP03_14580"
     CDS             13380..15107
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="NMP03_RS14580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NMP03_14580"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_256506201.1"
                     /transl_table=11
                     /translation="MIRDFLVVSRFLWRTTHGQIAWVILLSLITAATEGVSIMMLIPIV
                     AIASPDSSARAGDIPLIGDLLVRLSTSLPILLAIFVLLVAFQSLLNYAKNVFALTLMQI
                     ASDRLKHDLFKAVSAARWDVIAKRRLSDINQALISGIPRCMTAANAALMLMQGMLLIGI
                     YIVVAALLSWQMALFAAMVGGGLLAVMYPIRRRASRFGQDLTGLFEQQSHTTLEFLNGI
                     RLAKTFLAEGRFVRSFDRHLVEIRTNTLRFFTTNAVGTLIFQLGVAVIAALFVYLAMVH
                     FALGLGEVAVLLLIFARLTPRFNALQEQSQSFLSNAPAYGHYTDMLRYFASGREADVGA
                     SEPPRLTRMIELRDLTMQFDADAPPSLNRINVQIEAGRVTALVGASGSGKSTLADIVTG
                     LITPTSGQLLIDDVAIDQSNRRAWRSRVATVPQDALLFNATLRENLALGRPGASEADLW
                     QALERAQIADFIRALPDALDTQVGDRGTRFSGGERQRVALARALLSRPEILILDEATSA
                     LDIDNQQRVAAAIAGLRDGRLTILLIAHQPMITNIADVRIMLEHGMVVTGTDSLLPDG"
     misc_feature    13626..13628
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    14808..14810
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15277..16194)
                     /locus_tag="NMP03_RS14585"
                     /old_locus_tag="NMP03_14585"
     CDS             complement(15277..16194)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025025.5"
                     /locus_tag="NMP03_RS14585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NMP03_14585"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_256506202.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.5e-18,
                     bitscore: 64.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDHAMVVTDRLIASAVTICMCTFRRPAAFDALRSFEKLAGIPPN
                     AVELVVVDNDETDVLRAKFEAVAQCYPYPLRYIHAPAQNISIARNAALNATTTRWLAFI
                     DDDETADPNWLSALLEYRDQAETVIGQCIAVYGLDLPVWTARCDFHSNRIQGDATNAYT
                     SNALLDMDFVRRHGLRFRVELGRTGGEDSIFFRQMKEAGGRIIYCPQAVVYEPVPQTRA
                     TMTWVRRRMYRAGQTHGLLCREFDPKAYRNLWLTAGAKMVVSAAMVLITVPGSTPSRRW
                     FARTMLHAGAARYRLKPAMLEEYA"
     gene            complement(16187..17467)
                     /locus_tag="NMP03_RS14590"
                     /old_locus_tag="NMP03_14590"
     CDS             complement(16187..17467)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016800.5"
                     /locus_tag="NMP03_RS14590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NMP03_14590"
                     /product="O-antigen ligase"
                     /protein_id="WP_256506203.1"
                     /sec_met_domain="Wzy_C (E-value: 3.9e-15, bitscore: 53.8,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTRIQAGSLARVRTEPESWLRFNRASPVIDSLFAAYVAGSVIFA
                     TILQSLTPILIALATPLYCLLRWERVATVLLRCWPILLLPAFALTSALWSEAPAATLRY
                     GIFYLLTIMPALFIGAGSDRLASLKGMFAIFAIYTFASLVFGRYVSWGVSGIAFAGLAG
                     SKNMSGDLAALTMLLATTFGIWAMGQRRLVLAGFAVLTLLAALYALFASKATGALLAAG
                     MAIPCILLWTASRRLPVGLRTAIFALTVLIAIGVAASASYWMAPLFDMVLENSGKDQGL
                     TGRDFLWSMADRLIVERPLLGGGYRHFWLESNLDAQYVWREMMVPAGGGGFNFHNTPRD
                     ILVDLGIVGLILFTMVMIGGTFLTMFRTMLEPYYMGIFLCALIVFQAPRLFFELVAFQN
                     MHYSTLLVFMILAYGVRPAKVSQAEHA"
     misc_feature    complement(16418..16420)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16667..16669)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17303..17305)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17471..18043)
                     /locus_tag="NMP03_RS14595"
                     /old_locus_tag="NMP03_14595"
     CDS             complement(17471..18043)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /GO_function="GO:0015159 - polysaccharide transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs) SMCOG1186:
                     polysaccharide export protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008065671.1"
                     /locus_tag="NMP03_RS14595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NMP03_14595"
                     /product="polysaccharide biosynthesis/export family
                     protein"
                     /protein_id="WP_256506204.1"
                     /sec_met_domain="Poly_export (E-value: 3e-24, bitscore:
                     82.4, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHLIYHVRRILMATLILGLSACSGSLPPPGSAAYTATEYRLAAGD
                     RLRITVFGEENLSREYVVSSAGDLSFPLLGDIRASGTTVTELQAQLVTALAKGYINDPR
                     VNAEVLTYRPFYILGEVKNPGEYKFSDRLTFTQAVALAGGFTYRADQRRVFIRRAAGGQ
                     EETYVLSSDRPVYIAPGDTIRVGERYF"
     misc_feature    complement(17714..17716)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(18089..18098)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.75"
                     /tool="antismash"
     gene            complement(18114..19046)
                     /locus_tag="NMP03_RS14600"
                     /old_locus_tag="NMP03_14600"
     CDS             complement(18114..19046)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012745.5"
                     /locus_tag="NMP03_RS14600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NMP03_14600"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_256506205.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.1e-33,
                     bitscore: 112.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFAIACYNAGEYLAPAVASALAQTGVSVEVLIVDDGSTDGSVAV
                     AEGLARADARVRLFRTKTNSGPAGARNIALAEMRGSWFAVLDADDLILPNRSRTLIDLA
                     ERESADFVADNLTVFGKDVVEKPFLSHPISKGWRRLTLDTYFAQSRLLSDTPNPGFLKP
                     MVRRRVIEAAALRYNERLMIGEDDELVVRLLASGYTYFVLNMPLYRYRKHGASISHRLS
                     LDHAERMMAAEHRIRDLIGPELAARPSYYGRWLAMVRGLAFTRSIDLLKRRRPLAAALA
                     LLREPAAIPLYREPLMSALRQLIRRAKLR"
     gene            19120..19863
                     /locus_tag="NMP03_RS14605"
                     /old_locus_tag="NMP03_14605"
     CDS             19120..19863
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012376.5"
                     /locus_tag="NMP03_RS14605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NMP03_14605"
                     /product="metallophosphoesterase"
                     /protein_id="WP_256506206.1"
                     /transl_table=11
                     /translation="MRNPFKPRMKIGQTEPGERIYAVGDVHGRYDLMRNLLSLIMRDWE
                     ATARADTTIRILFLGDIIDRGPDSRSCIMLLQRLTSQPRIGLLRGNHEDLMLRSLDGEQ
                     WAQDIWMEQGGLTTLNNYGVAAPLRAEDSFDFAERLLAAIPPEHIAFLRSTPLFWASGT
                     YFFAHAGVRPGVSLYKQDDQDLISIRNEFLTADAWHGAVVVHGHSIVDDVDVRPNRIAV
                     DTGAWQSNRLSCVVLDGTTQNIITT"
     misc_feature    19141..19157
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.99"
                     /tool="antismash"
     misc_feature    complement(19141..19157)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.64"
                     /tool="antismash"
     misc_feature    19474..19476
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    19573..19575
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19860..21176)
                     /locus_tag="NMP03_RS14610"
                     /old_locus_tag="NMP03_14610"
     CDS             complement(19860..21176)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019128.5"
                     /locus_tag="NMP03_RS14610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NMP03_14610"
                     /product="cell wall hydrolase"
                     /protein_id="WP_256506207.1"
                     /transl_table=11
                     /translation="MSALAYNVAVFAKIARRKTNRRGSTKEKANMDRSVQLLGALIGLA
                     AMLIIGGMLAVSFALKNGEEVTAQAWKGRSDAQRALPPLPKAGMPGVVTPENELLPVLP
                     ETARRTNAMRPFSDKLNASARPFSSVLSADDRERAIACLAIAALYEAGGIGDDQYPVMQ
                     VILNRVRHPAFPGSICGVVFQGAERSTGCQFSFACDESMARWRPSDRAITEARARAAAM
                     LDSHVDRRVGLATHYHTDWVLPYWSNSLDKITAIKTHLFFRWRGYWGTLASFRQQSNNV
                     EPRIAALAALSSVHLAQVGQPGDPSALADIPVLSADAVAGGDDAVTVTSNARAGEARIA
                     VLNLPLDPDSKPGGWSLNALALCGKRPECRAVGWIDPTRRPATFDAASLAASPPDFVFV
                     QELRNRTQQPYWDCTKHAKASMSRCLESSDHPARLVYGG"
     misc_feature    complement(19971..19973)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(21999..22012)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     misc_feature    22239..22254
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.58"
                     /tool="antismash"
ORIGIN
        1 aggcttgctg taaggtagta cctggacgct acgggacgca ggcagcagcc gatcgagcgc
       61 cttacccagt gctttgtgaa aggtgagggt gtaagtggtc gttaggtggt ggcggtctcg
      121 gtagcggagg atgccgtcgt gcacgacggg gcacatctcg cccgggcaat atgcctcgga
      181 aaagtctagc agcgtcacat tgtctgcgtc cggcccaagc tccagtcgat cgtcggcgta
      241 gacgaaacga cgaggcaggc cgcattcgcc cgcatcattg gggtgcagtt cagcgcattg
      301 gacggcatcg cgttgcatcc acggattgtc gcgcagcgcg agcacaggga tgttatgctg
      361 gtccagcgca cgccatgcgg cacgatagct cgacggcacg gtttcgcgac catcaactgg
      421 cctggtcgcg atggtgaaca caagatgtgg cttcaattca gtgatccgcc ggaccgccgc
      481 ctcgttccat ttttcacagc tggcatcacg attcgcgccg atcggccgtc ccaaaccgaa
      541 ataacaggcg cttttcgtca agttgacaac cttaagggcc cgcgacggcg ctagcgcctg
      601 cagcaccggc agccattgcg cggagtgcga tccgcctacc agcaccacca ccgtggcccg
      661 gccgtgcttc acgccgtaca tgcattcgat cagcaccgcg gatcgttcat cttggtggca
      721 accatcggcg tagacgggcg agatgtcacg tcgtgcgacg atggcgtccg ggaacatctg
      781 gtccgaggcc ggaaagagtt tgccttcacg atgggcaagc accctcgccc aggcctgacg
      841 ctccttggtc cggttcagca gttttgcacc tgcgatcgcc ccggctgcgg gcagcatcac
      901 caacccgcac gcgaccagcg tcagcgccgg tcggccggtc aggtgcgcat ggcgccggaa
      961 cggcgtttcg gcgaagcggg tcgaggcata agctagcaag gcggcaaaca gcaggatcgc
     1021 aacgccagcc gccagaccga catcctgccg gtcgagcaac aaacgcgcgc agacgagcag
     1081 cggccagtgc cacaggtaga agctgaagga gtaatcccct gcccggacca gcggcgtcca
     1141 ggtcagcacc ggcactcggc ccccgttctg agccgccacg atcacggaaa cggcggcgag
     1201 gacaggcacg gcggcaagta cgcccggaaa ttgcgatgac acgtcgatca ccgccgcgaa
     1261 cccgagcagc acgacgagtg ctgctaggcc tagcacacgg gccgcacccg gagagagtcg
     1321 gatgcggtgg atcgtgagcg caagcagcgc gcctgccgcg aactcccatg cgcgagcgaa
     1381 cgtgtcgaaa taggcgcgcg gttgaaaccg agcggtttcg aaaatgctcc acagtagcga
     1441 cgctactaac agcacagcaa aggcgaacag cagcgccgtt cgcggctgaa cgcccgttcg
     1501 gcgggctagg tgcatcaccg cccaaataag tagcggaaag atgaagtaaa attgcacttg
     1561 caacgatagc gcccacatct gctggaacgc agacgagctc aagtcgcgcg acagatagtc
     1621 ggttccttcg ttcgcaaggt tccagttctc cagaaataga atggatgcca gcgcatgacc
     1681 gaattctgat cgccagctcg attcgggcgc aatcgccagc acggccagaa ccgtcgtcaa
     1741 gacaaccagc gcagtccccg gcaggacccg tcgcgctgtc aacagccaat agtcacgaac
     1801 ggccgtgaca cgcagcgcgg accatttgac gaacgagcgg gtcatgaaga aagcggcgac
     1861 tacaaaaaac acgtcgacgc cgccggacac ccggccaagc catacatggt agaacgcgac
     1921 caacagcgcc gccacagtcc taagtccttg gatctcgccg agatattccg ggcgcgtgtc
     1981 ggcacccgtt gtttgtgcca gcatgctacc cccgatgtgc cgccctttaa cgtccacgat
     2041 acaccaccct cgaccccaag caccatagct atggttgggc ggcaacatca tgcctgccgc
     2101 gttgccaaac cacacggctt ggacccgaat gcagccttgg cccactcgct agagcccttc
     2161 gcaccagtgc tatttcggct ttcggagctg tcggtcaata ttatgcagcc gcggacaaca
     2221 tgtatatggc agtgtgcctc acaatccgat gcctccggca gatcaggcgc ggttcgccca
     2281 ctccgcaacg gtcagatcgc tgccgtagcg cagggctgtg cggctattta gcgcgcgggc
     2341 ggtcggttcc aaatgatgcc ttccaggtct ggtcatctgg tcccgcatcc gctcggaatc
     2401 acatccaagc tcgaccgttc accgttacgc cgccgttctg gcacggcctc atagggttca
     2461 cgtgagcgcg cctggatcat gatcaatgag gcccgcggaa ataaaatggc gggaagacgc
     2521 cgacggtcaa catgtggcga tgccaaaagg gaaatgatag gagcctttat gaagggatga
     2581 tttatcgccg tgggagcggg atcttcaacc gccttcttcc cgatccactt ggtcgactgg
     2641 gtcagtcaaa gttagagcga gcaagtccca tgacgcgcgg cagctcacgg tggatgatga
     2701 ctctgagttc ctctcgccgc ccgagcgcct cgagtatctg gtcttggatc tcgtctggtc
     2761 gctccgcgaa gttcttaggg tcgtacaaaa cactttcttc agtcaaccct atcagttgat
     2821 agagaccttc gaacttgcct tgatagacga aactgatcgc cggtgttcct gcgctcatag
     2881 cgagaatcgc ggcgtgcata cgtccagtca caatggcttc caatttggag agaacctgcc
     2941 tgacaaagga aggttcatgt gcgttcagga gatggacatg ttttgcgctg tcgggatcca
     3001 agcgtagttg cagctcggac agcagtgttt cgtcgctccg ctgcccgcgg ttatcatgtg
     3061 gcaccagaag aacgctgtag ccttcaccaa gaaggcgtct caggaagttg tcatgggcgc
     3121 tcgtgtaacc gacaacagtc cgatcgatgt tagcgttgat gttgagtccg atcatgggac
     3181 gtttcgcggc cgcttgggcc tcgaggaaat tacgcgtatc gtcaggaatg gcgtcgtcac
     3241 ccgcaggcat ggtaaggaaa gcaaggtccg ccgtttgtct gactacacgg ccggcagcgg
     3301 cctgaagtct ttctcttgaa accgggtcgc gcgcattgat gcatacattg gatgctaggt
     3361 gacgaagggt cctaattgcc tcggcatgcg gcttcgtcga gaagctgctt cccaaaattc
     3421 gggcgtcacc gccgatgcgg gcgtgctcgt cgagcaacac cattcggcgg gttatggagc
     3481 cagggttata agtaccgtct atgcaatccg cgccgactaa cattgtgtgg gagaaagccg
     3541 acgcttccag aatcccgtgc gccagcacgc tccgtcgtcc gtcaaaaaac catttgttca
     3601 gatcgtgata ggagtcaaat ggcggaaggg cgtcccatcc agctgggaga gctacagaaa
     3661 cgcgactgaa gccagcagtt ttcagctcat tataggccac cgtcagcata gccgcgtccc
     3721 ccacgctgcc agcttgcgtc ggcggaataa ttaaaacagc tcgtttatca ttgcttcggt
     3781 aagctagtcg ccgagcacct tctcgtcgcg ctcgagtaag caacacactt acaccaaaac
     3841 ttctgagcat actgatcatt ccccatcgtc cttgtcgcca cgcatggcca atctgaccgc
     3901 aacgccttta tgtactttta ccagtccctg ccattgtcgg ggtcgaaaag tcactcacat
     3961 tatgcactgt ggtgtcgcaa gcggcagaca gggttctgta atctgcagtc cttcctgcag
     4021 acagggcagc agctggtttc aagcctgtgc tggacgagct tgagcaccgg atggccgcgc
     4081 gccgattcag gcgcagcgga gcttgtcgga cacatggttt cgacgtaccg ccccctgctg
     4141 cccccgttac ggccaaggaa agaccgatga ctgatccgcc ctcgccgaag ccgctgcaac
     4201 tcggtcggct cgccctgcaa ggggggctcg tgacggggct ggcccaggcg ttgaagatgg
     4261 cactcagtct tgtgtcggtc gtcgtcctgg cgcggctgct cgcgccacag gacttcggct
     4321 tggttgcctc gatcgcgccc atcgttgcct tcatcgcatt gttccaggac ttgggactgc
     4381 aggcggccat cattcagcgg gagacgatca cccgtgaaca cctgaaccag acattctgga
     4441 tctcgcctgc cattgcatcg gtcgccgcgc tattgatcat agcggctgcg ccgctggctg
     4501 cgctattcta caatgaccag cgcgtaaccg ccatcatggt ggtcgctgcc gtgccgatct
     4561 tcatcggcag cctcgcaact ctgcctctta gtctgctgaa ccgcaatatg cgcttcggca
     4621 atctggcgct gaacgacgta ctggttgctg cgacaggatt cggcgccaca gtgggtgcgg
     4681 ccctgctcgg ttccggttac tggtctcttg tcatcgggcc aatcgcggct gccctcacag
     4741 cggtcatcgc cgcttggatc gcatcgcctt ggcgtccggg acggcccacc ctgaagttgg
     4801 atggagacct ttggtcgttt ggcgccaatc tcacaggatt caatatcgtc aatttccttg
     4861 cgcgaaactt cgacaatgtt ctcattggtc gagtttcagg catgacccaa ctgggtctct
     4921 atgatcgatc ctacaaactc ctgctgtttc ccctgcaaaa catctctcag ccgctctcca
     4981 gagtgatgat tcccatcctg agccgcgtac agaacgacaa ggcccggttc agaaaaatct
     5041 acctgcagac caatatggtt ctcgggtttt gtctcattcc ggggatcgcg gcggctacgc
     5101 tggcgtccga tcagctcatc aatctgttgt tcgggccgga gtggagcgct gcggcaccga
     5161 tcttcgcctg gcttgggatc gcgagcctgg cccaggtcgt actggtcacc aatgggtgga
     5221 ttttcatttg tcagggcaag acgcgggcga tgttccgcct tggcttatgg acctcgggcg
     5281 tcacggtcat cgcgttcctt gtgggtatcc agtggggcgt cgtgggtctt gcggccgcct
     5341 atacgataag cgcatatctc ttccgcatac cggccctcat cgccgtactt cacagaatcg
     5401 gccctgtgac ggcaagcgac atgtcaggtc tcctattggt ccatctgctt ccggcagcat
     5461 taagcgcagc catcatctgg gcagcgaatc tcgaagcctg ggaactgtcc gatgtggtta
     5521 gcataggcat ctgcgtggtg ctcaactact gccttgcgac gttgtcggtc gcgatctttc
     5581 cgccggcccg ctctgccatg gtcgaggtgg tggggagatt ggccaacttg aggcgtcggc
     5641 aggtcgtctg acatctgatc ggggctatta tgtcatcacc cgagtccggc cggattttgg
     5701 atgcgatgct caaggcgtca gagggaccgt gatgcgactg aaccgcaggc gtacactttg
     5761 gtgccgtgcg acgcgcggcg gacgccccgc cgctgcctcg cgccgcgcgt cgatcggctc
     5821 agccacgcct agccgttgcg ctcgagcgcg accccgtaca attccgtccg atggtcaggc
     5881 ctgacgggcg gattagagtc cggggtcgtt gacaggatgc ttgtcggtcg aattccttcg
     5941 caggttgacc gttcaaatgg ggtcgcagcg tcgcttcaga atccatgaag tgacgtcgat
     6001 ttcctcggat cgcggccaca tgcgtatgag acaaacttcc atcaaagcaa atcaggacat
     6061 aatgaagtgc gcaatctcgg caccgatggt gttccagtcg taggcggaca gatcggcgcg
     6121 ttcgggaccg cctgcacgca ggtggtttgc gaacagacgc acggcgtttt ggtcgaacgg
     6181 aggcttgaag agcgaaaccc agtcctgtcc cagagactgt tccagttccg gaaggcttcc
     6241 gatcgccgga gcaaggatgg gcttgtttcg accgatcgcg tggagcgcga cgccactgtt
     6301 gagaatcttt gtgtagggca gcaccacgcc gtcgtgcgcg tcgatgatgg cattgagttc
     6361 cgagtccgta agtagatccg atcgaagatc cagattgatc ctattcgatc catttgaggc
     6421 taactcgatc cgatctctga gaccggggtc aaagcaggtt ccgacaatcg taagtgtgat
     6481 gtccggatcg tttgccgcgt ggaacgcctg gatcaggccg atgacattct tgtattccct
     6541 tatgagccca aacatcagca gccttatgtc gcgcgaaacc agtcgacggg gcgagggcgc
     6601 gtctgtgccg tctgggtacc ggccatgacg cgtaatgagg tgcggcgcgg attcgaagtt
     6661 ggggtaggcg gcgataaagt cgcgtctaga gctgttcgat aagaaaatga aaccactgac
     6721 aagacgcaga aacatatgag tcgccatcgg cgcctggatt tcaccttcgt ggggcgacat
     6781 gttgtggaca acccaataca cgcgagtgcc tctggcccta agagctataa gtcgaaataa
     6841 caagacgagt gtatttcttc ggctttcctg tataaagaaa tgatttggcc agtgatatat
     6901 tataatatca ggacgactgt ccttagccgg gttgtaattg cggtcaacaa tttgcaatcc
     6961 ggcgtccctt aagcttgttg agaacagctg gggatacgca tttgaagcca tccgcacacg
     7021 gtccagcgcg acgcggactg ccggacggga cgtgcggtcg ttcttagtca gaagaggcag
     7081 cggcggtctc cggtatgatc gcattggcgc tcggaactag gcctagcttt cgaggcgagt
     7141 cgctaaaccc agtccctcaa tacgctgact aggcaacgcc ttgatatttg acaacgctcc
     7201 gcggccgtgc ggtgtcgtgg gagccgtcgg tcatcgaaag cgtcacaaag gtcgggaccc
     7261 ataaacttga ttccctgggc ggatggaatg tgattcaggc tcggcaacag cagaaccgtg
     7321 aattgagtgc gttctggttg agcggggagc agttcgagcg gtttcgacta tagatgctgg
     7381 acaaggtgcg cgccgttgcg cggggcgatg accgacgggt gatcagccgc atcatccatg
     7441 tggccgatcg tgcgggcgct gggttgatga acccgcctac tacggtccga gaaggacgct
     7501 ctacaacacg ttagtgcggc gggccgcgga aggcatccgg cacgagatgt tcgtcacgtt
     7561 gacagcagcg ggtggactgc gcgccgaggt cttgatcgac agcacacata tgaaggccca
     7621 ccgctcggcg gggcgccgaa aagggggcgc tgatccaggc gatcgggacc agccgaggcg
     7681 gtcgcagcag caaaccccac gcgcttaccg acgctgaagg ccgcccgctc agcttcctgc
     7741 agacggtggt aacgtcgccg actgccgtgc tgctgatgtc ccgctcgacg atcgcgcgcc
     7801 gcactatcgt gctggccgac aaggcgtatg atagcaatgc gatccgtgac ctgatcgagc
     7861 gccagggtgc cgtgcccaac attccctcca aggcgaaccg gctttggaaa cgctgcttct
     7921 accgcccgct ctacaaaagc agcgacgctg tcgagcgcat gttccgcctc gaggattatc
     7981 ggcgcatctc caccgctatg ataaacttgc caccaacgtt ctcggcgcaa actacctcgt
     8041 ggcagccatc atctggggat tatgggtccc gacccttatc caacgtgaac acagggcggc
     8101 cacgagatgg ccgcgcctct cgaacacact tgccggtcat aacggtcgga aaacgaggcc
     8161 ttcacccagg cgatccatcc ttcgagaagg caatgccgca ccaaacgttt aaggcgccca
     8221 ccgtagaaat caaattgccg ttgttggggg tgcccagatg acgcccgatc ggcgacgcta
     8281 ccgttagccg ccaaaattta ttttgatggg atcgcgatag atcggatggt attatcgttc
     8341 aaaccgagaa cttcgtagat ccttcgctta tttcggtaga gacagacctt cgcggcgcaa
     8401 agcgagttct gcccttgcga tgcgtgagag cgcgatcgtg aaaaggccgc cgcggcgtag
     8461 taggttgcca tccatccaat gccacaattt actggtgcgt tcgaagcgca cagatgcagg
     8521 atgtccaatc gaacttagcg ccgcccgctc gaaatcagcc gatgcctcgc ccgaactcgc
     8581 gaaaagcagt ttgctcactg ctaggcattc atccactaat ccctggagat tattccggcc
     8641 agcaaggttc ctcactgcgg ttaactcatc cctcgtcata gatcgcgtca tccacgcaaa
     8701 ttcatgcatt tccgccagcc acggctttcg agcgcgtacc gccttgccgt aattgatcgc
     8761 gcagactagc aaagcgtgat gcggggagag cgttcggatc gcattcgaac cgatgttctg
     8821 gaccatgctg gctgcgaaga actcctccat ctggcggggg taagggccgc cgggctgttg
     8881 cacgcggtga tgcagatcaa caatggggct ggtgctgtcg gggcgtgcat agggcgattc
     8941 gcccaggcat cgatgccacc agatcgaagt atcggaaaca agcgcgatca ttccgtcggc
     9001 agctagaatc tgctgtgcgt ggcaatactc ttcggggcgc accaacaaat cgatatccga
     9061 cgaccgccgc gcgtcccatg ttgcatagac atggtgggac cgaagtgcac ctttgaacac
     9121 gatcgggtcg attccgcccg cttgaagcgc gtttacagtc tttatcgtcc aatcgaaatt
     9181 ccgcagattg gtcagcagga tatcgcgccg ggcgcttaca atctgttccg caacgatggc
     9241 aggtacccct gctgctggat cgccggccac tcggcccagc aatcctattg tcttggttgc
     9301 ggtcgcggcc gcaagcaccg aaccccaatc tgcgacagct ggtatttcgc cagccggcgt
     9361 taggccgttt cccagccacc gcagcagatc caaagaactt tgcaggggca ccttgtcggc
     9421 acagagagcg ttgttcattg cttgagccat cgtgatggcc gctaatcggt tttgcaggtc
     9481 cgagcaagtc gggacgccgc ttcattctgg tgcccacaca gcgttaaaac cgacacgatc
     9541 tcgcgattgt tacgcaagcg atccgtgaaa tcccgggttg ggacacagat tgcgcggtta
     9601 ccgtaccgtc ggatcggatt gattgacgaa gtgttaaaga agcgttagcg aattgttacc
     9661 cgatctactg tgagtcggct gctgatcgtt gtcgaggttg cgattggtaa tgtttcggtc
     9721 gaacgcacct aacctcaatg aactaggaga tattttatgg ttaagcgcac ctatcagcgt
     9781 cctgcaatgg aactccttgg gtcgtttgag acccttacga agggcggcgc gactggtaac
     9841 gctctcgatg cagcgtttcc tacgggcacg cctttcagcg agctgacctt ttcctaatta
     9901 cgggtgaagg ttgaaaaaga agagcggttg ccgcaaggtg gccgctcttt ttgcttatta
     9961 gcggctttgc ggagaagtat gcgtgtctac atctgaccca atggctcgcg cgcggtacgt
    10021 cgcgaacaag gatgtcgtta cctgcgagct cgatagtggc caggcgctgt tgaaccttcg
    10081 tacaagccaa tatgtgaaat tcaacgagac ggccggactt gtctggcaat gggtgcagga
    10141 tggtttgacc gtcgatcaga tggctgacca gatgtgcacc atgtttgatg ctgagcgtaa
    10201 tcagtgcagt gccgatatcg cgctgttgct ggggcagttg aaagaggcgg gccttgtcga
    10261 gcttgaggct gaataggctt ccgcgttatc tgcggcttgt caggcggcac catcggtcac
    10321 tgatcgcggc gttcgtcacg ttgcttatcg ttcgcatcgg gctgacgcta ggctcctatc
    10381 gcttggtact gcggtggatc gagcgctatg cacgtcctag ccgccgtccg acggcggttt
    10441 tggtgctcgt ttggtcggtg aggcattccg ccaagctcgt cccgggcgca agctgcctca
    10501 ctcaggcgct cgcgatgcga tacctgatgc tgcgcgcggg cgagggctgc acgatccgga
    10561 tcggcgttcg cgagaccgcg aatcgtccat tcgatgccca tgcctgggtt atgtatcaag
    10621 ggcgcgtgct gatcggcggc aacgaacagg atttggcagc ctttaagcca ctggtggatt
    10681 tgtgatccat ctgatgccgg acaaatcggg ggttcgagta acctggcacg atttgggtac
    10741 ggaaccgaac ggattgggcc ccagtctcgt gttcatctcg cccggcaccg cgattgactt
    10801 ctccgcgcag atgtccgctg agcttggcct ttcggtagct tcgggaaccg aagcaatatt
    10861 gctggccgct tgggcgaaat gggacgtcgc gatggtcgat cgcctgcgcg gggatttcgc
    10921 cttcggcatt tacgatcccg cccaaggcgt agtgttcctg ggccgcgata ttttcggacg
    10981 tgcgccacta tattatcatc ttgatgggga tgggctcgtc gtcgccggaa cgtcgcggct
    11041 cgtccgggca atccttgggc gttcgctcgc gcggaacgag gctttctatg ccgattttgt
    11101 ccagggacag ttcgtcgagc aaagcgcgac gtttttcgaa ggattagaac gcctcgcacc
    11161 tgcgcattgg atgaagatcg atcggggggg cagggagctc tatcggtact ggtcgcccca
    11221 aagcgtccgc cagcacacaa cgatgcccga cgctgccgag cggtttcagg cattgttcga
    11281 ccactcggtg gcgcgtgcga tgggcggtgg cgacgcgctg gtgctcctta gcggcggact
    11341 ggattcctcg gccattctgg ggtcggtcat ggcggcaaac gatggcgggc tggcccccga
    11401 ttgcctgacc aaaacctatc gccgcaccaa agactgggtc gacgagccct atctgcgatc
    11461 actcggggcg caatatgggg tgtgcccgcg cgagatcgcc tgcgatgaac atgatcccct
    11521 cgctgatctt gatcgctggc tggatgtgct tgacgggcca tatttttcct acggccattc
    11581 ggtaacagct cacctactgg atatagcgag ggggatgggg cgcctcactt tgttgtcggg
    11641 gcatggcggc gacgaagtgg ttggctatgg tatcgggcgg ctcaacgaac ttgcacaaca
    11701 acggcagtgg ctgcggttgt ggcgtgaggc ccctggtctg actgcgctat cgggctcgtc
    11761 acggctgcgg gtaatgcgga aatatctcac gcattatcca cgatatcgtc cgtttgaacg
    11821 acttttacag aagcagtttc cggatacgcc gtcagatgag gaagcatcgc tctcggccaa
    11881 tttgctcgcc gcgatgggtg agaaccgata cgcgtcgcag cccgccgtca atcgcgggga
    11941 tcacgacgaa cctaccgttc atgccgaagc gctgaatgac gtggtgcagc cgcttgcgct
    12001 cgagaccatc ggacaatgca gccgcgcggc cggggtaaat accgagatgc cattctacga
    12061 tcgcgatttg gtcgagctga ccttgtcttt gccttctgag tggaaattac gcgacggttt
    12121 cacccgctat gtgatgcggc gtgcgatgga gggccgcctg ccgcgggacg tgctgctacg
    12181 gcaggacaag ttcgatttta ccgacgcctt cgtagcgggg ctgatcgcgc accgccaccg
    12241 agcgttagcg ttgactgaca atgtcgacgg ctccttggat agctatgtga acctgccgcg
    12301 gctagcagcc gcgcgcgcgc aattgtcacg atctgagcgg gccatcacga aggcggatgc
    12361 gcgttttatc tggcggtgcg cggtactagc gatgtggctc aagcgatatg aaaccagtcc
    12421 cccgccgcct atgatggtac cactgacaca aggattaata tcttgaaccg atatcgggcg
    12481 ttcggactgc tgatcgaaag cgatttcctg ttaccggagc tcagcattgc cgattcgcgt
    12541 gacgggcctt gcgatctgcg gatcgtccgc gccgacattg gtcgtgaaat ccccgaacca
    12601 aatgctcagc ctgtgttcga ctatgaagac ccttcgggca ccgtgatgat ctggccgcag
    12661 gttgctggat ttcgctttcg cgcgcctgat cttatcgagg tcgagcccgc gccgaatgcc
    12721 aagtccgaac tgttggcatt tccgctgctt ggcccggtga tgggttggtt tctgcatctg
    12781 cgtggtcgga tggtgctcca cgccagcgca gtcgtctggc gcgggctcgc atttggcttt
    12841 ttgggcgata agctggcggg gaagtcaacc acagcggcgg cgtttctgcg cgatggggcg
    12901 caactgctga ccgacgacct gctggtattt gccatggacg atcctgccgt accgttggtt
    12961 cagccggcct ttgcccagtt gaagcttggc gatgatagtg ctgcagccgt cacgatcgcc
    13021 ggtgcaaaag cattgccgtt ggtaatggac ggcttcgcca agcgccagca tcggctgcat
    13081 cggctggcgg ctgcacctgc ggcttgcgac gctttgttca tactcgaacg cggtgatggc
    13141 cctgcggtca tcgaatggct ggaccaaaag gatgcgtttc taggattgat gcggttcggc
    13201 tataatgtgc gctttgctaa cgccccgatc gcgatgcaaa atcgccagcg caacttcgag
    13261 cagtgcgtgg cgcttgcccg gtcgcttcgc ttcggcgtct tgcgtgtgcc cgcagacctg
    13321 actcgtctcg acgaggtgct ggaagcagtc gcggaatcgc ttgcgaagcc gacgacggca
    13381 tgatccggga ctttctggtc gtttctcgct tcttgtggcg aacgacccat ggccagatcg
    13441 catgggtcat cttgttgtcg ctcatcaccg ccgcgacgga gggggtgtcg atcatgatgc
    13501 taatcccgat cgtggctatt gccagccctg atagctcagc gcgtgcgggc gacatcccgc
    13561 tgatcggcga tttgctagtt cggctgtcca cgagcttgcc aattctgctg gcaatcttcg
    13621 ttctattagt agcgttccag tcgctgctga attatgcgaa aaacgtattt gctttgacgc
    13681 ttatgcagat cgcatccgac cggctcaagc atgacctgtt caaggcggta tccgcggctc
    13741 gctgggatgt gattgccaag cgtcgactgt cggacatcaa ccaagcgcta atcagtggca
    13801 tcccgcgctg catgaccgcg gccaacgccg cgctgatgct gatgcaagga atgttgctga
    13861 tcggcattta catcgttgtg gctgcgctgc tgtcttggca gatggcgttg ttcgcggcga
    13921 tggtgggcgg cgggctgctc gcggtaatgt acccgatccg ccgtcgggcg agccgtttcg
    13981 gccaggattt gaccggattg ttcgaacagc aatcgcatac cacgctggag tttctgaacg
    14041 gcatccgcct ggcgaagaca tttttggctg aggggcggtt cgttcggtcg ttcgatcggc
    14101 atttggttga aatccgcacc aatacgcttc gattttttac gacgaatgcg gttgggacgt
    14161 tgatatttca actgggcgta gccgtgatcg cggcattgtt cgtttatcta gcgatggtgc
    14221 attttgccct tggattgggc gaggtagcgg tactcttgct gatcttcgcg cgcctgaccc
    14281 cgcgatttaa cgcgcttcag gaacagagcc agtcgttcct atcgaacgct cccgcatacg
    14341 gccattatac tgatatgctg cgctattttg cgtccgggcg cgaagccgac gtcggcgcca
    14401 gcgagccgcc gcgcctgacg cgcatgatcg agctgcgcga tctaacgatg cagttcgatg
    14461 ccgatgcacc gccctcgctg aatcggatca atgtgcagat cgaagcaggt cgcgttaccg
    14521 cgctggtcgg cgcatcgggc agcgggaaga gcacgctggc ggacattgtg actgggctga
    14581 taaccccgac gtcgggtcag ttgctgatcg acgacgtcgc gatcgatcaa agcaaccggc
    14641 gggcatggcg cagtcgggtg gcgacggtgc ctcaagatgc cttgttgttc aatgcgaccc
    14701 tacgcgaaaa cctggcgctg ggcaggcccg gcgcgagcga ggcggatctt tggcaagccc
    14761 tggaacgcgc gcagatcgcc gactttattc gggcgctgcc cgatgcttta gatacgcagg
    14821 tgggcgaccg cgggacccgg ttttcgggcg gcgagcgtca acgcgtggcc ctagcccgcg
    14881 cattgttgag ccggcccgag atactgatcc tcgatgaagc aaccagcgcg cttgatattg
    14941 acaaccagca gcgtgtcgcg gcggcgattg ccgggcttag ggatgggcgt ctcacgatcc
    15001 tattgattgc gcatcaaccg atgatcacaa atattgccga cgtgcgcatc atgttggaac
    15061 acggcatggt ggttacaggg acagactcgc tgttgcccga tgggtgaggc agacgcgccc
    15121 cctgtttctg gtccccggcg cggtcagcaa tgcgtcgccc ctgcgcgttg atcccgcggg
    15181 cgctaggtcg tttgaaaagc ggacaggtca aggccgaaac cgcgcgcaaa attgtcgacc
    15241 gtttttggac ggatacgctc ccggaacatt cgtggatcag gcatattctt cgagcattgc
    15301 cggcttcagc cggtatcgtg cagccccggc gtgcaacatg gtacgagcaa accagcgacg
    15361 tgatggcgtg ctgccgggaa ccgtgatgag caccatagcc gcactgacta ccatttttgc
    15421 cccggcagtc agccacaggt tgcgatatgc cttcggatca aactcccggc acagcaggcc
    15481 gtgggtctga cccgcccggt acatccgcct gcgcacccaa gtcatcgttg cgcgcgtttg
    15541 cggcacgggc tcataaacca ccgcttgcgg gcaatagatg atacgcccac ccgcttcctt
    15601 catttgacga aagaagatgc tgtcttcacc cccggtccgc ccaagttcga cgcggaaccg
    15661 cagcccgtga cggcgtacga aatccatgtc gagcagggcg ttgctggtat aggcgttggt
    15721 ggcatcgccc tggatacggt tggaatggaa atcgcaccgt gcggtccaga caggaaggtc
    15781 aagcccataa acggcgatgc actgaccgat cacggtttcc gcttggtcgc ggtactccag
    15841 cagtgccgaa agccagttcg ggtcggcagt ctcatcgtca tcgataaagg ccagccaacg
    15901 cgttgttgtg gcattcagcg ccgcgttgcg tgcgatcgag atgttttgcg cgggtgcatg
    15961 gatgtagcgc aaagggtagg ggtagcattg cgcaaccgct tcgaacttgg cccgcagaac
    16021 gtcagtttcg tcattatcga ccacaaccag ctcgaccgca ttgggcggaa tgccggcaag
    16081 cttttcgaag gacctaagtg cgtcaaaggc agcggggcgc ctaaaggtac acatgcagat
    16141 ggtgactgca ctcgcaatca aacgatcggt taccaccatt gcgtgatcag gcatgctcgg
    16201 cctgcgacac tttggcgggg cgaacgccat aggccaagat catgaagacc agcagcgttg
    16261 aataatgcat attttgaaac gcaacgagtt caaaaaacaa ccttggtgcc tgaaacacta
    16321 tgagtgcaca aaggaaaatc cccatataat agggttcaag catcgtccta aacatcgtca
    16381 ggaatgtgcc accaatcatc accatcgtga aaagtattaa gccgacgata cccagatcga
    16441 ccagaatgtc gcgcggagta ttatgaaaat taaacccccc tcccccggcg gggaccatca
    16501 tctcacgcca gacatattgc gcgtctagat tgctctctag ccaaaagtgg cgatagccgc
    16561 cgccgagcag cggcctttcg acgattagcc tgtcggccat gctccacagg aagtcgcggc
    16621 ccgtaagacc ctgatccttg ccactgtttt ctagtaccat gtcgaataac ggcgccatcc
    16681 agtagctggc actcgcagca acgccgattg caattagcac ggttagcgca aatatcgcgg
    16741 tcctcagccc gaccggcagc cgacgcgacg cagtccatag caagatgcac ggtatcgcca
    16801 ttccggcagc aagaagcgcg ccggtcgctt tgctagcaaa tagcgcgtag agcgctgcaa
    16861 gcagagtaag cacggcaaaa ccagccaaaa ccaaccgtcg ttggcccatt gcccagatgc
    16921 cgaaggtggt cgccaacagc atcgtcaaag ccgccagatc gcccgacatg tttttcgaac
    16981 cggccaaacc ggcaaaggct atgccgctga caccccagct gacgtatctg ccaaacacca
    17041 ggctggcaaa ggtgtagatc gcgaaaatag cgaacatacc cttcagagag gccaaccggt
    17101 cgctgcccgc cccgatgaag agcgctggca taatcgtgag caggtagaat atgccgtagc
    17161 gcagcgtcgc tgcaggtgcc tcggaccaca gggccgacgt cagggcgaac gctggcagca
    17221 acaggatcgg ccagcaccgc agcagcacgg tcgccacccg ctcccagcgc agcaagcaat
    17281 aaagcggggt cgcaagcgcg attaagatag gcgtcagcga ttgcaatatc gtggcgaaaa
    17341 tcacgctgcc agcgacatag gccgcaaaca agctgtcaat cactggcgaa gcgcggttaa
    17401 atcgaagcca ggactcgggc tccgttcgaa cgcgggccaa tgatcccgct tggatgcggg
    17461 tcaccatgat ttagaaatac cgctcgccca cccggattgt gtcaccaggc gcaatataga
    17521 cagggcgatc ggaggaaagg acgtaggtct cctcctggcc gccggcggca cgtcggataa
    17581 atacgcggcg ctgatcagcg cgataggtga agccgcccgc cagcgctact gcctgtgtga
    17641 acgtaaggcg atcgctgaat ttatactccc ccgggttttt aacctcgccc aagatgtaga
    17701 aggggcggta ggttaatacc tcggcattaa cgcgcggatc gttgatatag cctttggcga
    17761 gagcagtgac gagctgtgcc tgcaattccg ttacggtcgt tcccgatgcg cggatatcgc
    17821 cgagtagcgg gaacgacaaa tcgcctgctg acgagacgac atattcgcgc gacaaatttt
    17881 cttcgccaaa cacggtaatc cggagacggt cgccagcagc caaccggtat tcggttgccg
    17941 tataggcggc gcttccaggg ggaggcaaac tgccagaaca tgccgagaga ccgaggataa
    18001 gcgttgccat caagatgcgg cggacgtggt aaatcaggtg cattcgatgg aatcccttcg
    18061 gaggtcgcgg gactgaccat gattcgcatc aaaaatcaat ttctaatgcg ccgtcatctc
    18121 agtttggcac gtcttatcag ctgtcgcaac gcgctcatca gcggctcgcg gtaaagcggg
    18181 atcgccgcgg gttcgcgcag cagcgccaac gccgctgcca gaggacggcg gcgcttcaac
    18241 aagtctatgg accgggtgaa ggcaaggccg cgcaccatag ctagccagcg accgtaatag
    18301 gatggtcgtg cagccagctc aggaccgatg aggtcgcgaa tcctgtgttc ggccgccatc
    18361 atccgttcag cgtggtcgag cgagagccgg tgcgagatcg aagcgccgtg cttccgatag
    18421 cggtacaggg gcatgttgag gacgaaatag gtgtatccgg atgcaagcag gcggacgacc
    18481 agttcatcat cctcgccaat catgagtcgt tcgttgtagc gaagcgctgc cgcttcgatc
    18541 acgcgccgac ggaccatcgg tttgagaaat ccggggttgg gtgtgtctga aagtaggcgc
    18601 gactgggcaa aataggtatc aagggtgagc ctgcgccaac ccttactgat cgggtgcgaa
    18661 aggaagggct tttcgacaac gtctttacca aagaccgtga ggttgtcagc gacgaaatcg
    18721 gcgctctcgc gttcggcaag gtcgatcagc gtgcgactac ggttgggtag tatcaagtca
    18781 tcggcatcga gcacggcaaa ccaagatccg cgcatttccg ccagcgcgat gtttcgcgcg
    18841 cctgccggtc ccgagttggt cttggtccgg aacaacctga ctcgggcgtc cgcgcgagcc
    18901 aatccttcgg caaccgcaac gctgccatca gtgctgccgt cgtcgacgat gagaacttct
    18961 acgctgacgc cggtctgagc aagcgctgag gctaccgccg gggcaagata ttcgccggca
    19021 ttatagcaag cgattgcgaa actcacgtct gggggccggc aatggccggt gtgcgaaaca
    19081 gtcactgaca ttgacggcat cagcctccat aatgctgaga tgcgcaaccc gttcaagcca
    19141 cgcatgaaaa ttgggcagac cgagccaggc gagcgaatct atgccgtggg cgacgttcat
    19201 ggcagatacg atttgatgcg caatctactt tcgctgatca tgcgagattg ggaagctaca
    19261 gcgcgggctg acaccacaat ccgtatcctg ttcctcggcg atatcatcga tcgcggaccc
    19321 gatagtcgat cctgcatcat gttgctgcaa cgcctgacct cgcaaccaag aataggcctt
    19381 ctccgcggaa atcatgaaga tttgatgctg cgatccctag atggtgaaca atgggcacag
    19441 gatatttgga tggagcaggg tgggcttacc accttaaaca attatggtgt cgccgcaccg
    19501 ctaagggccg aggatagttt tgactttgcc gagcggcttt tggcggcgat cccgcccgag
    19561 cacatcgcgt ttttacgtag cacgccgttg ttctgggcca gcggcaccta tttctttgcg
    19621 catgctgggg ttcgtcccgg cgtctcgctt tataagcagg acgaccagga tctgatctcc
    19681 attcgcaacg agttcttgac tgcggacgct tggcacggag cggtagtggt gcacggtcat
    19741 agcatcgttg acgatgtcga tgtgcgcccc aatcgcattg ctgtcgatac cggcgcatgg
    19801 cagagcaacc ggctatcttg cgtcgtgctc gacggcacta cacagaacat tatcacaacc
    19861 tagccgccgt agactagtcg agcaggatgg tcactagatt ccaggcagcg gctcatcgat
    19921 gccttggcgt gttttgtgca atcccaatag ggttgctggg tacggttgcg taactcctgc
    19981 acgaacacga aatcaggggg cgatgcggcg agacttgccg cgtcgaatgt ggcgggacgc
    20041 cgggtggggt cgatccagcc caccgcgcgg cactccggac gttttccgca aagcgccagc
    20101 gcgttcagtg accaaccgcc cggttttgaa tcggggtcga gaggcaggtt gagcaccgct
    20161 atccttgctt cgcctgcacg agcgttcgac gtgaccgtca ctgcgtcatc cccaccggca
    20221 acagcgtcgg ctgaaagtac agggatgtcg gcgagggcgg atggatcgcc aggttggccg
    20281 acctgcgcga ggtgcacgga cgagagggcg gccagcgcgg cgatacgagg ctctacatta
    20341 ttgctttgct ggcggaacga ggcaagagtt ccccaataac cccgccaacg aaagaacagg
    20401 tgggtcttga tcgcagtgat cttgtcgagg ctgttgctcc aatagggtag cacccagtcg
    20461 gtatggtaat gcgtggccaa acccactcgg cgatcgacat ggctgtcgag catcgctgcg
    20521 gcacgggcac gcgcctctgt gatcgctcta tcggacggtc gccagcgcgc catcgattcg
    20581 tcgcaggcga agctgaactg gcaaccggtg ctgcgttccg ccccctgaaa tacaacgccg
    20641 cagatgctgc cgggaaaggc ggggtgacgc acccggttga ggatgacctg catgacggga
    20701 tattgatcgt cgccgatgcc gcccgcttca tacagcgcgg cgattgcaag acacgcaatc
    20761 gcgcgttcgc gatcgtctgc tgatagcacg gaggaaaagg ggcgggcgga ggcattaagc
    20821 ttgtccgaga agggacgcat agcgttcgtt ctgcgcgcgg tttcaggcaa gaccggcagc
    20881 aattcatttt caggcgtaac gacgccgggc atccctgctt taggcagggg cggcaaggcg
    20941 cgctgcgcat cgcttcgccc tttccaagcc tgagcagtta cttcctcacc gttcttcagg
    21001 gcgaacgaga cggccagcat cccaccgatg attagcattg cagccaagcc aataagtgcg
    21061 ccgagaagtt ggacggaacg gtccatattg gccttttctt ttgtcgaacc gcgtcgattg
    21121 gtttttcgcc gcgctatctt ggcgaaaacg gcgacattat aggcgagggc cgacatatca
    21181 catatgcgat ttgcttaacc gttccagcgt tgggatcgtt ccatccaaca tccgttgccg
    21241 ccaatgatgc gatgcccatg ggtttttgct gcgatatggc tactggcagt gcagctgcgc
    21301 gaaaagcctc gagcggggat atcacgagtt tcggaccgcc tccgaacgcc cagacgtagg
    21361 gatccggcgc tgatgggctg gcagcgtata attaagcaat cgacgggggt gcctgggcgc
    21421 agggtcggat catgacggca gtgccatgga tcctcaatcg ctcgatcccg atggccacgc
    21481 cgagtctacg tatctttcgt gaagatctat ctagacagct ccaacaacga ccagcctatt
    21541 tcgccgacgc ctgcccaagc aaaagtcctg agcaaaacac gccaaagcca tgcgtgtggt
    21601 gacgtgcccc ccagaattca tggcattggt aagttagctc gtcagatgga gacgagtggt
    21661 gcggcgaagc cggcttacca aagagcagat cgttggggtg ctgcgggagc atgaggcggg
    21721 cgtgaagacg cctgagctat gccgcaagca cgagcttagc gatgcgacat tctataactg
    21781 gaagtcgaag tacggcagga tgacggtgtc ggagggcggc acggtttcac acattggaaa
    21841 aggagaaacg acggcttaag aagctgctgg cggagtcgat ggctgacgtg tcggcgctga
    21901 aggatctgct ggggtaactg gtcttgtctg gggagcgcta tgcggtggtg gagacgctga
    21961 tggccgatca cggctgctcc gagcgtcgcg cctgcagact gatcagggtc aatcggtcgg
    22021 cgtggcaata tgagccgcta cgcgggaagg acgatgctgt ccgcgagcgg atgcgcgcga
    22081 tcgccaacga gcgacgccgg ttcggctatc ggcggctggc gatcctgctc aagcgtgagg
    22141 gcaagggcat gaacctgaag aaggtgtatt ggctgtaccg cgaggagcgg ctgacggtgc
    22201 gcaagcgttg tcgtcgcaag cgcgcgctgg ggacgcgggc gccgatggcg atcccgcagg
    22261 aacccaacca gagccgatcg ctcgacttcg tatcggatgc actggcctgc ggccggcggt
    22321 tccgtatgct gaacgtcatc gacgattaca gccaggagcg cctggcgtgc atcgtcgata
    22381 cctcgctgtc aggtgggcga gtcatccgcg atctgagtgc catcgccgaa cgtcgcgggc
    22441 tgccgtgcat ggtagtcagc gatgat
//
