LOCUS       NZ_AP026074            21059 bp    DNA     linear   CON 31-DEC-2024
DEFINITION  Streptomyces nigrescens strain HEK616 plasmid SNP1.
ACCESSION   NZ_AP026074
VERSION     NZ_AP026074.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces nigrescens
  ORGANISM  Streptomyces nigrescens
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Asamizu,S. and Onaka,H.
  TITLE     Complete genome sequence of Streptomyces nigrescens HEK616
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1073703)
  AUTHORS   Asamizu,S. and Onaka,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2022) Contact:Shumpei Asamizu The University of
            Tokyo, Graduate School of Agricultural and Life Sciences; Yayoi
            1-1-1, Bunkyo, Tokyo 113-8657, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: HGAP4 v. 4.0; Falcon v. 0.3; Canu v. 0.7; Arrow
            v. 2.3.3; Pilon v. 1.22
            Genome Coverage                   :: 262x
            Sequencing Technology             :: illumina Hiseq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024349765.1-RS_2024_12_31
            Annotation Date                   :: 12/31/2024 04:23:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,326
            CDSs (total)                      :: 8,236
            Genes (coding)                    :: 8,032
            CDSs (with protein)               :: 8,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 204
            CDSs (without protein)            :: 204
            Pseudo Genes (ambiguous residues) :: 0 of 204
            Pseudo Genes (frameshifted)       :: 84 of 204
            Pseudo Genes (incomplete)         :: 166 of 204
            Pseudo Genes (internal stop)      :: 16 of 204
            Pseudo Genes (multiple problems)  :: 56 of 204
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:47:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 269620
            Orig. end                         :: 290679
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP026074.1.
            Annotated by DFAST https://dfast.ddbj.nig.ac.jp/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21059
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21059
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21059
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11059](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11059)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            467..1045
                     /locus_tag="HEK616_RS37835"
                     /old_locus_tag="HEK616_76980"
     CDS             467..1045
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018101494.1"
                     /locus_tag="HEK616_RS37835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_76980"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_261957769.1"
                     /transl_table=11
                     /translation="MSPRVPKAELPTELRENMIKQLGAVPEPVEVVWHSPKVATSNLEF
                     SAKLAEWDAADEGLKSFAHMAVAAQVGCSWCLDVGYFQAQNQNLDLAKASQVPRWRESD
                     VFTPLERDVLEYAEAMTHTPPTVTDEMYASLLDRLGPAAMVELTAYIAFVNMATRNNNA
                     NGVASQGFSEACEVPLARRPERSGAATTA"
     gene            1042..1893
                     /locus_tag="HEK616_RS37840"
                     /old_locus_tag="HEK616_76990"
     CDS             1042..1893
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016436770.1"
                     /locus_tag="HEK616_RS37840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_76990"
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="WP_261957770.1"
                     /transl_table=11
                     /translation="MTEDPFVTHRTLLFTVAYEMLGSAADAEDVLQDSWLRWADVDRTQ
                     VNDPRGYLVRIVTRQSLNRLRTLSRRREEYVGEWLPEPLLTSPDVAEDVELAESVSIAM
                     LTVLETLGPAERAVFVLREVFDLPYGEIAEAVGKSAAAVRQIARRAREHVAARRPRVRV
                     SRSEQQAVVERFLAALRTGRVQELMEVMAPDVVLIADGGGLAAAARAPLHGAELVASLL
                     ARPGRAVSPVWLNGAPAGRIEIDGRLAAVSLVVEDGRVTRIHAVANPQKLTRLDEPAEL
                     AR"
     gene            2013..2930
                     /locus_tag="HEK616_RS37845"
                     /old_locus_tag="HEK616_77000"
     CDS             2013..2930
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057502.1"
                     /locus_tag="HEK616_RS37845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77000"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_261957771.1"
                     /transl_table=11
                     /translation="MSLRITPLTDPEDGQYSRRLAWLASDADAIPVGTAFLRLFTAAGQ
                     DHVAELAVQVHPAERRGNVGSRLLDVAVAAARDHARRSVTAQADAGSPGDAFLSARGFR
                     KVLTLRFTRLPLADVDPAALDEIVARPHPGYRLASWRGTVPDDLAQTFAASRRAMDDMP
                     MDDTDYGTVVWDVDRVRAAARTVAERGDLLHTVAAIDESDGSIAGFTELVVPGSGEGDG
                     QHYGTGVLPEHRGHGLGRWMKAESIRHAHGHYPKLGALLTDTADSNTHMRHINEALGYV
                     PTHEVLQYQLDLEGGTRGPGRSPA"
     gene            2944..3726
                     /locus_tag="HEK616_RS37850"
                     /old_locus_tag="HEK616_77010"
     CDS             2944..3726
                     /NRPS_PKS="Domain: Aminotran_4 (38-252). E-value: 2e-26.
                     Score: 85.1. Matches aSDomain:
                     nrpspksdomains_HEK616_RS37850_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009999096.1"
                     /locus_tag="HEK616_RS37850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77010"
                     /product="aminotransferase class IV family protein"
                     /protein_id="WP_261957772.1"
                     /transl_table=11
                     /translation="MAHLDGKPVTTDDVLPLALTSYGHFTTMRADADHRIRGLSLHMDR
                     LVRDCRTVWGAGLDTGRVRQFVRQALEGQRGPCMIRVTVYDPAVEVGHPADADQPQALV
                     TVRPAGAMPPPPLRAMSVPYERDLPQVKHCGLFGALHIRRAAQFAGFDDALFIGPDGYV
                     SEGATWNVGFIDDDGTVVWPQAPVLPGITMRLLQQQVAHRIAPVTLAQAKGMRAAFATN
                     TGIGVRALTAVDDAPLAVEDPVLSTLREAYLSIPGEEP"
     aSDomain        3058..3699
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEK616_RS37850_Aminotran_4.1"
                     /evalue="2.00E-26"
                     /label="HEK616_RS37850_Aminotran_4.1"
                     /locus_tag="HEK616_RS37850"
                     /protein_end="252"
                     /protein_start="38"
                     /score="85.1"
                     /tool="antismash"
                     /translation="LSLHMDRLVRDCRTVWGAGLDTGRVRQFVRQALEGQRGPCMIRVT
                     VYDPAVEVGHPADADQPQALVTVRPAGAMPPPPLRAMSVPYERDLPQVKHCGLFGALHI
                     RRAAQFAGFDDALFIGPDGYVSEGATWNVGFIDDDGTVVWPQAPVLPGITMRLLQQQVA
                     HRIAPVTLAQAKGMRAAFATNTGIGVRALTAVDDAPLAVEDPVLSTLREAY"
     gene            3830..4381
                     /locus_tag="HEK616_RS37855"
                     /old_locus_tag="HEK616_77020"
     CDS             3830..4381
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093602.1"
                     /locus_tag="HEK616_RS37855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77020"
                     /product="FABP family protein"
                     /protein_id="WP_261957773.1"
                     /transl_table=11
                     /translation="MSDPAAPKHPYPDAFGPDEAPAPHALLAPLIGLLGTWVGRGRGGY
                     PTLAEEFGYAQEVTFSHDGRPFLRYEARAWLLDTDDAPLRPAARESGWWRLQPEGRVEA
                     LITQPTGIAEVLVGRAGDGTVDLTTHQVALAPTAKEVTATRRRYDLTDQDTLSFVHDLA
                     AVGRPLQHHLAAELRRVGRS"
     gene            4463..5608
                     /locus_tag="HEK616_RS37860"
                     /old_locus_tag="HEK616_77030"
     CDS             4463..5608
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010352837.1"
                     /locus_tag="HEK616_RS37860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77030"
                     /product="hypothetical protein"
                     /protein_id="WP_261957774.1"
                     /transl_table=11
                     /translation="MTDRLGETMNWSRLMGVMAAGLVLGGCATSASTTEAARSPKASAH
                     DAHPTGAHRTAGHGKGGSTSDAKAHHPLFTVVGNLDARPGQLVVTQLDGVACGQGDAPV
                     VATSPAFRGPVRLHWQNGSCGSTSALAMTAKPGSYPLSITVAGRTVARDKIKVVRSRRP
                     SLSLTPVSEVARPGAPVWLYFDDLYPGERGTHFTVRSAALSRTVRLAHDRQLDFYNPRT
                     FQARPQLRPGLADGTYTFELRGPHGRHIMEKRLTVRASRPGDPDYLGKAHGPDLYEPGT
                     YADSPHRHSFRVARGGKVEVMWHDVNPDPGEEMRLTATSPAFTHVLHLRADDSKSADGD
                     DPRFLNTATIRADLEPGRYPVTVVAHHGRVKKVGYVIVTAR"
     gene            complement(5660..6091)
                     /locus_tag="HEK616_RS37865"
                     /old_locus_tag="HEK616_77040"
     CDS             complement(5660..6091)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013003966.1"
                     /locus_tag="HEK616_RS37865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77040"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_261957775.1"
                     /transl_table=11
                     /translation="MDSISGPYELRAGVPSVEVFRRLRTDAGLSDRAPDAVALALPHTW
                     YGVVLHHEGEPIGMGRIIGDGGTAFQIVDICVHPAHQGQGLGKRIMAALTEELESRAPA
                     TAYVSLIADGPARHLYEKFGFADTAAHDSVGMYRFMNGS"
     gene            complement(6147..6776)
                     /locus_tag="HEK616_RS37870"
                     /old_locus_tag="HEK616_77050"
     CDS             complement(6147..6776)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091443.1"
                     /locus_tag="HEK616_RS37870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77050"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_261957776.1"
                     /transl_table=11
                     /translation="MGRLIVTAFVTLDGVMQAPGGPNEDVDRGFPHGGWQVPYVDEDFM
                     DLMTGIFERTADHLLLGRKTYDIFAAHWPRVTDENNPIAVKLNSMPKYVASRTRDSLEW
                     HNSHLLKGEAAQSVAQLKEQLDGVLMTQGSSDLIHTLQQHDLVDEYRLLVNPVIIGTGK
                     RLFGEGATPVAWTLTESRTTGAGVQYCAYERAGTPEYGSFALDEEG"
     gene            complement(6982..8427)
                     /gene="argG"
                     /locus_tag="HEK616_RS37875"
                     /old_locus_tag="HEK616_77060"
     CDS             complement(6982..8427)
                     /EC_number="6.3.4.5"
                     /GO_function="GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0006526 - L-arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1291: argininosuccinate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550593.1"
                     /locus_tag="HEK616_RS37875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77060"
                     /product="argininosuccinate synthase"
                     /protein_id="WP_261957777.1"
                     /transl_table=11
                     /translation="MSKVLTSLPAGERVGIAFSGGLDTSVAVAWMRDKGAVPCTYTADI
                     GQYDEPDIASVPGRAKTYGAEIARLVDCRAALVEEGLAALTCGAFHIRSGGRAYFNTTP
                     LGRAVTGTLLVRAMLEDDVQIWGDGSTFKGNDIERFYRYGLLANPHLRIYKPWLDANFV
                     TELGGRKEMSEWLLAHDLPYRDSTEKAYSTDANIWGATHEAKTLEHLDTGVETVEPIMG
                     ARFWDPSVEILTEDVTIGFDQGRPVTINGKEFATAVDLVMEANAIGGRHGMGMSDQIEN
                     RIIEAKSRGIYEAPGMALLHAAYERLVNAIHNEDTLAQYHNEGRRLGRLMYEGRWLDPQ
                     ALMVRESLQRWVGAAVTGEVTLRLRRGEDYSILDTTGPAFSYHPDKLSMERTEDSAFGP
                     VDRIGQLTMRNLDIADSRAKLEQYAGLGLIGTANPAVGAAQAAATGLIGSLPEGGAEAI
                     ASRGEVSGDDEWLDRAAMESGTD"
     misc_feature    complement(8427..8445)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.18"
                     /tool="antismash"
     misc_feature    8430..8448
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.19"
                     /tool="antismash"
     misc_feature    8448..8461
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: strong, score: 19.46"
                     /tool="antismash"
     misc_feature    8490..8503
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.9"
                     /tool="antismash"
     gene            <8752..9021
                     /locus_tag="HEK616_RS37880"
                     /old_locus_tag="HEK616_77070"
                     /pseudo=""
     CDS             <8752..9021
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017771.5"
                     /locus_tag="HEK616_RS37880"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77070"
                     /product="DUF899 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="RQWTNLRLLSAGSSTFKYDLGSEDAEGNQDSTVSVFTRDGNGDVR
                     HFYSAHPRMAEDIDQRGIDLLCPVWHFLDLTRHGRGDWFAALGY"
     gene            complement(9094..9969)
                     /locus_tag="HEK616_RS37885"
                     /old_locus_tag="HEK616_77080"
     CDS             complement(9094..9969)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574303.1"
                     /locus_tag="HEK616_RS37885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77080"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_261957778.1"
                     /transl_table=11
                     /translation="MTIAHADTARTPVPTQSTYQSRVADYWNAEENPVNLELGKIDDLY
                     HHHYGIGDADRSVLEEPDPDRRRERITGELHRLEHAQAELLASHLGGLSPTDRVFDAGC
                     GRGGGSVVAHLRYGCHTDGATISAKQADFANEQARKRGIDAKVRYHHRNMLDTGFTSGA
                     YAASWNNESSMYVELDLLFAEHARLLRRGGRYVVITGCYNDAYGRASREVSLINAHYIC
                     DIHPRSAYFRAMARNRLVPVHVQDLTAAALPYWELRRQADHLVTGIEDTFLNAYRNGSF
                     QYLLIAADRV"
     gene            complement(10001..11059)
                     /locus_tag="HEK616_RS37890"
                     /old_locus_tag="HEK616_77090"
     CDS             complement(10001..11059)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093087.1"
                     /locus_tag="HEK616_RS37890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77090"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_261957779.1"
                     /sec_met_domain="T1TS (E-value: 3.4e-51, bitscore: 170.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPPNTSAGFALPGPPSLARSSQARRGGAVPGLRYRPAVPADPD
                     KVKEVDRRLEAWARRLDLFPAQWTGDFTQFQFGRAVVLQHPGAADLERLTAAGELLLAE
                     NLVDSCYCEEDEGRGGARRGLGGRLIMAQSALDPFHGTAETEEEWRGGVQADGPLRSYH
                     CALKDYAAFATPSQTGRFVHDMARLHLGYLAEASWAETRHVPEVWEYLVMRQFNNFRPC
                     LSIVDAVDGYELPEPLYARPEVQRVTALACNATTIVNDLYSFTKELASDPTHLNLPQVV
                     AANDKRGLKAAYLKSVGIHNQIMEAFETESAPLAALSPLLERYVRSLADWVSGNHEWHA
                     TNTDRYHLPNYW"
     gene            complement(11078..12520)
                     /locus_tag="HEK616_RS37895"
                     /old_locus_tag="HEK616_77100"
     CDS             complement(11078..12520)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576907.1"
                     /locus_tag="HEK616_RS37895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77100"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_261957780.1"
                     /transl_table=11
                     /translation="MSVPDSVTGPAAEEPDLEPPADSALTSLSTQAARQLATTTKSEPQ
                     MQAITSRWLVKMLPWVDVKGGTYRVNRRLQLRVGRGRVQFEQNGADDIRVIPQTLTELP
                     VLRGYDDIEVLKEIAGRFRVREVRAGQTLFEAGQPATEAYLVVHGRFSRYTAGKYGEEE
                     VLGVVTDGDQMGDEAIGRPDPRWQSSVRAETAGVLLALPWDVIREFTDRVPSLAAHLAA
                     YAERQQLPANRKGEADVPVQAGHVGEPTLSGGFVDYDLAPREYELSLTQTVLRVHSRVA
                     DLYNDPMDQTQQQIRLTVEEIRERQEWELVNNREFGLLHNTDYGQRISTHTGPPTPDDM
                     DDLLAMRRKTRLFLAHPKAIAAFFRQCNRRGLVPGTADVNGHQVPAWRGVPIFPCGKIP
                     ISDTNTSSIIALRTGEADQGVVGLYQTGIPEEFQPGLNVRFMGIDQAAVIRYLITAYYS
                     VAILVPDAAGVLENVQIGRSTD"
     gene            12874..13026
                     /locus_tag="HEK616_RS37900"
     CDS             12874..13026
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEK616_RS37900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_261957781.1"
                     /transl_table=11
                     /translation="MDDLLKLVTPYVTRLCGPIAPRDTADAVPESLLAVFRGAARAAGS
                     TYSGS"
     gene            complement(13105..14301)
                     /locus_tag="HEK616_RS37905"
                     /old_locus_tag="HEK616_77110"
     CDS             complement(13105..14301)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511147.1"
                     /locus_tag="HEK616_RS37905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77110"
                     /product="hypothetical protein"
                     /protein_id="WP_261957782.1"
                     /transl_table=11
                     /translation="MTYRHAAIPALAGGVVLTALLWWAGTSAHALHLPGATNVIGGPAT
                     ADLEHWLAPWSYDPPSSTQLNGEASGGIGGEALVDSARYLSLYTTALQIRFGAVFAFFL
                     LGALLLVRRLPPVRGGRGRTAAALLATWAWGVVAGTLAVAVSAPWMIAAGGHGSFRFLP
                     RLAGVIGSGRQILVLAALVAAVVTVVAARVTAKETAPLPPAEVPARAARLAATVGTAVI
                     AVSLMVLSYQSVAAALQTVSPNIGLLSEPGDLLRQWLLFGAWTDPAGTPLGDWLLYRAA
                     DVLLLVVVWWALRRLPALLTRATVPAMAVGAVCATVLGLLASQLLRMATDGTGLQWGLL
                     HLAAGLGEGIPAALTWGLLAGVAAAVTLRLAGGRPKTTDATAPAQAPGQDPDQDIAEA"
     misc_feature    14278..14295
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            complement(14497..14922)
                     /locus_tag="HEK616_RS37910"
                     /old_locus_tag="HEK616_77130"
     CDS             complement(14497..14922)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538994.1"
                     /locus_tag="HEK616_RS37910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77130"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_261957783.1"
                     /transl_table=11
                     /translation="MTLSIGEREQFLAEPHIGALSVVERPDRAPLTVPIWYQYTPGGEL
                     WVRTGPDSRKARAIRAAGRFSLMVQRTEPTVRYVSVEGPVIRTEPDSRERSWEMAARYL
                     PQDKVADFVEFDQAQLGAHVVIYLQPEHWVSADLGSF"
     misc_feature    complement(14902..14916)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.32"
                     /tool="antismash"
     gene            complement(15028..16266)
                     /locus_tag="HEK616_RS37915"
                     /old_locus_tag="HEK616_77140"
     CDS             complement(15028..16266)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009079025.1"
                     /locus_tag="HEK616_RS37915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77140"
                     /product="MFS transporter"
                     /protein_id="WP_410011384.1"
                     /transl_table=11
                     /translation="MRSTELPTDTAISSAHLPDGTSTLHKKLPMGALLALAIAVFITSL
                     TETLPAGLLPAMSAGLHTSESATGQTVTIYALGTVLTAIPLSAATAGWRRKRLLLTAMA
                     GFAVANTVTAWSANYPLTLVARFVAGVAAGLAWALLAGYARRMVAPHQEGRAIAIAMAG
                     IPVALSLGVPAGTFLGQVVSWQAAFLAMTALTLVLLVWIAVAVPDYPGQKAGGKLPMRR
                     PLRVPGVAPVLFVTLVFVLAHTILYAYIATFLRHIGLGDQTDAALLVFGIASLASIWIV
                     GTFIHGHLRTLTLAGAVLVGVAAAVLGAFSGSHALVYVAAALWGLGWGGIPTLLQTAAG
                     QAGGEAADAAQAMLVTLWNAAMAAGGIIGGLLLQAVGADAFPWTVLTLLVPVLVVVLAA
                     RAHGFPARRAGSS"
     gene            16405..16821
                     /locus_tag="HEK616_RS37920"
                     /old_locus_tag="HEK616_77150"
     CDS             16405..16821
                     /EC_number="3.1.2.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024675.5"
                     /locus_tag="HEK616_RS37920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_77150"
                     /product="acyl-CoA thioesterase"
                     /protein_id="WP_261957784.1"
                     /sec_met_domain="4HBT_2 (E-value: 2e-14, bitscore: 50.0,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKLFTHRLRVRYSECDQQNVVFNGHYLFYYDVAVTELWREAAGG
                     YASMLAGGADLVVAEARIRYRQGARFDEVLDIEMPVTHLGTTSMIVCPRFKVGERLIAD
                     GEVRHVFTDAVAGGKREMPGVIREAFQPYLSAGE"
     gene            17037..20645
                     /locus_tag="HEK616_RS37925"
                     /old_locus_tag="HEK616_77160"
     CDS             17037..20645
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEK616_RS37925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEK616_77160"
                     /product="hypothetical protein"
                     /protein_id="WP_261957785.1"
                     /transl_table=11
                     /translation="MDIALPTDDTGGPDHCCVFLSDNRTGGPVSGALAFLEAQLTVSEE
                     GSGGEVGAAARAGQSVRIPLGLLGSDHAGYLSWDLAPLWRQVLQLEERPDGSTAEVRVA
                     HVWLYLGGPLQSAVDVLAEADERAQALVLRLGVDRGGVFTGSTSGFPAMQSPSLLDWYL
                     SPGSFAYVPAELIGQDGCETLLPSNVATQQYQVHQIVTVPDLMASLDYGAQYTAPAGDG
                     SGTSDHSAPSDRSDGSHPSHSSHRLAGFPVPVALVISYDVTWLPVGHGLGQVTYSLPLA
                     PGEQVQLAVVDWSRTSTDSRLEDIALTDDLEHALTRDRTVDEVVKGAVNEWQRGGSVMT
                     GAAGAASMGMFGGSAAIGGGYATTSGDRSVSADTVQNLHDQIRQHSTSVRDMRSTVVVQ
                     SRQAENSTAQTRTVRNHNHAHAMTLLYYEVLRHFRVLVERGRVRRAVLLPAASPDLDDE
                     LVIVRYRRLLQAGLLDPQLAGGFDAVEKYAAWRELQPEVPVPPDPGSVEFILFQFRFTI
                     GDLSSFQDRVPTTVTLTQRAPDGGQKVTGLIRPQHSDWDPDPTHLQNPGDFQHTHAVVD
                     LAGVPRADERVNWRDLRTISVTLIPPHTEGRNDDVAVEHLVVTAVDTAGNTHLLVDEPS
                     GKLFQKPSTTWALAARQAPEPAPAPTPFQRLSDDENLLRIRLRRHLVQNREHYYRLIRL
                     GEDPNARWTELAGSTLTVGGTTRPLFQAVENRALEVLGDATAFPLDPALFDGAGEGQVR
                     LPEVDPARSEQLVSLPTRGVFAEAKLGHCNSAEVIDNTRFWDWQKSPDPDSAPQIAPVS
                     TASREVVVATTPSGLPTSAVTIVQPPQAPDPVGLAAALQLLGKGDIFRDESMQKEIAAL
                     LTSLASDAAGLAGKTPGTPGTPGTPGTGSTPGTGTGGGPGTGTPGTGTGPGAPTGGGTG
                     TPGGGTPGGGNGTGGGTPPGSGGTPANPGGTPGTTGPGTQPGSGDGGPGTPKPPAPAPH
                     PTPRPPVPIGSDNRSFVFSFAPVSFGPSEADWERGRFAIAIFQDGKPVLSQDNVEPAAP
                     SVILNGRVAPDKPLDIVVDGSSTHWVTYPSIYSSAMAGNPSTLGTPPGILITTHLVGKL
                     TLAGLDPKQRSHVFSIRRDVKFTSVTLSEQQIRQQGLEKVVSGQINASFDKVISFGAGL
                     SSSETSSTSTGTTTNKTDTVPVTFFTGLMSISPVKN"
ORIGIN
        1 ggatcaccgc gaccttcgaa ccgcacggcg gtcgcttcct cgtgcacgcg tcgcagcacg
       61 aggtggcgga gggcagctgg cccgggcacg tcgtggtgat cggctttccc ggcatggccg
      121 aggcgcgggc ctggtgggac tcgcccgcct accaggagat cgcaccgctg cgttcgcggc
      181 acatcgaggg cgacatcatc ctggtcgagg gcgtacccga gggttacgac ccccgcgcca
      241 ccgcgaaggc cctacgggag tccattccgg ctgagtagcc gatgagttga accgtgccgc
      301 gggccgccgg gtggccacag ctcccgcgcg tgcgcgccgc cgccgtcccg tggacggccc
      361 gcgcaccgga aaccggatca ccgctcaacc accgttgtca catccgaagg cgcggcggtg
      421 tcttcatggc gtaacggcag acatacacat ctacagggag aacaccatgt cgccacgcgt
      481 tccgaaggct gagcttccca ccgagctccg cgagaacatg atcaagcaac tcggtgccgt
      541 gcccgagccc gtcgaggtgg tgtggcacag ccccaaggtc gccacgtcca acttggagtt
      601 ctcggccaag ctggctgagt gggatgcggc cgatgagggc ctcaagtcgt tcgcgcacat
      661 ggccgtcgcg gcgcaggtcg gctgcagctg gtgcctcgac gtcggctact tccaggcgca
      721 gaaccagaac ctggacctgg ccaaggcgag ccaggtaccg cgctggcggg aatcggacgt
      781 gttcacgccg ctggagcggg acgtccttga gtacgccgag gccatgacgc acacgccgcc
      841 gaccgtcacc gacgagatgt acgcgagtct gctggaccgg ctcggcccgg cggcgatggt
      901 cgagctcacc gcctacatcg ccttcgtcaa catggcgacc aggaacaaca atgccaacgg
      961 ggtcgcctcg cagggcttct ccgaggcctg cgaggttccg ctggcccgtc gtccggagcg
     1021 ctccggcgcg gcaacgacgg catgaccgag gacccgttcg tcacccatcg caccctcctc
     1081 ttcacggtcg cctacgagat gctcgggtcg gcggccgatg cggaggacgt gctgcaggac
     1141 tcctggctgc ggtgggccga cgtcgaccgg acacaggtga acgatccgcg ggggtacctc
     1201 gtccggatcg tcacccggca gtcgctcaac cgcctgcgga cgctgtcccg ccgccgcgag
     1261 gaatacgtcg gcgagtggct gccggaaccg ctgctgacca gccctgatgt cgccgaggac
     1321 gtcgaactcg cggagagcgt ctcgatcgcg atgctgaccg tgctggaaac gctcgggccg
     1381 gcggagcggg cggtgttcgt gctccgggag gtcttcgacc tgccgtacgg cgagatcgcc
     1441 gaggccgtcg ggaagtccgc ggccgcggtg cggcagatcg cacggcgggc ccgcgagcat
     1501 gtggcggccc ggcggccgcg ggtgcgggtg agccggtcgg aacagcaggc cgtggtggag
     1561 cggttcctgg ccgcgttgcg taccggacgg gtccaggagc tgatggaggt catggcgccc
     1621 gacgtggtcc tgatcgccga cggtggcggg ctcgccgccg ccgctcgggc tccgctccac
     1681 ggggccgaac tggtggcgtc gctgctcgcg cgtcccggcc gggcggtgtc gccggtgtgg
     1741 ctcaacggcg cgcccgcggg ccggatcgag atcgacggcc ggctggccgc ggtgagcctc
     1801 gtggtggagg acgggcgggt cacccggatc cacgcggtcg ccaacccgca gaaactgacg
     1861 cggttggacg agccggccga actcgccagg tagaagcggc tgttgacccg actcgtgggt
     1921 gttccgggcg gtgcgaaccg cccggaacac ccatgagcgg gccacgttgt gccgctacgt
     1981 tatgcctccc accccctcac gacggagaca ccttgtcgct tcgcatcacc ccactgaccg
     2041 accccgaaga cgggcagtac agccggcgtc ttgcatggct ggcgtccgac gccgacgcca
     2101 tacccgtcgg gacggccttt ctccgcctgt tcaccgccgc cggacaggac cacgtggccg
     2161 aactggccgt ccaggtccat ccggcggagc gacgcggcaa cgtcggttcc cggctgctcg
     2221 acgtcgccgt ggcagccgct cgggaccacg cccgacgcag cgtcaccgca caggccgacg
     2281 ccggatcgcc cggcgacgcc ttcctgtcgg cccgaggctt ccgcaaggtc ctcaccctgc
     2341 ggttcacccg cttgcccctg gccgacgtgg atcccgctgc cctggacgag atcgtcgcgc
     2401 gcccgcaccc cggctatcgg ctggcatcct ggcggggaac cgttcccgac gacctcgccc
     2461 agaccttcgc cgcctcgcgc cgtgcgatgg acgacatgcc catggacgac accgactacg
     2521 gcacggtggt ctgggacgtg gaccgggtcc gagccgccgc ccggaccgtc gcggagcgcg
     2581 gcgacctgct gcacaccgtt gccgccatcg acgagtccga cggctcgatc gccggcttca
     2641 cggaactggt cgtccccggg agcggtgagg gcgacggcca gcactacgga accggcgtac
     2701 tgcccgagca ccgcggacac ggcctcggcc ggtggatgaa ggcggagtcg atcagacatg
     2761 cccacggcca ctacccgaag ttgggcgccc tgttgaccga caccgcagac agcaacacgc
     2821 acatgcgaca catcaacgaa gccctcggtt atgtgcccac gcacgaggtc ctccagtacc
     2881 agctcgatct ggaaggcgga acgcgcgggc cgggccgcag cccggcctga catgctgtgg
     2941 ggcatggcgc atctcgacgg aaagcccgtg accaccgatg acgtgctccc tctggcgttg
     3001 acgagctacg gacacttcac gaccatgcgt gccgacgccg accaccggat ccgtggtctg
     3061 tccctgcaca tggaccgcct cgtacgggac tgccggaccg tctggggcgc cggcctggac
     3121 accgggcgcg tccggcagtt cgtccgccag gcactggagg gacagcgcgg tccgtgcatg
     3181 atccgggtga cggtctacga ccccgcggtg gaggtcggtc accccgcgga cgccgatcag
     3241 ccccaggcgc tggtcaccgt acgcccggcc ggggcgatgc ccccgccgcc gctgcgcgcg
     3301 atgagcgtcc cgtacgagcg cgacctgccc caggtcaagc actgcggact gttcggcgcc
     3361 ctgcacatcc gtcgcgcggc acagttcgcc ggcttcgacg atgccctgtt catcgggccc
     3421 gacggttacg tcagcgaagg cgcgacctgg aacgtcggct tcatcgacga cgacggcacc
     3481 gtggtctggc cgcaggcccc ggtgctgccc ggcatcacca tgaggcttct gcaacaacag
     3541 gtcgcgcacc ggatcgcccc cgtcaccctg gcccaggcca agggcatgcg ggcggcattc
     3601 gccaccaaca cgggcatcgg cgtccgggcg ttgacggctg tcgacgatgc cccgctggcc
     3661 gtcgaggacc cggtgctgag cacgctgcgc gaggcgtacc tgtcgatccc cggtgaggag
     3721 ccctaggggc acggacacga gggcgagcgc cggcgtccgg cgcgcgtccg gcgcaccggc
     3781 tctaggcttc caccggcacc gacctcccca ctcatcagga gcgcacctca tgtccgaccc
     3841 cgccgccccg aagcacccgt accccgacgc gttcgggccg gacgaagcgc ccgccccgca
     3901 cgcactgctc gcgccgctga tcggactcct gggcacgtgg gtcggccggg ggcgaggcgg
     3961 gtatccgacg ctcgccgagg agttcgggta cgcgcaggag gtcaccttca gccacgacgg
     4021 acgtcccttc ctccgctacg aggcacgcgc ctggctcctc gacacggacg acgccccgct
     4081 gcggccggcc gcccgcgaga gcggctggtg gcggctgcag ccggagggac gcgtggaggc
     4141 gttgatcacc cagcccaccg ggatcgcgga ggtcctggtc ggccgggcgg gcgacggcac
     4201 ggtcgacctg accacccatc aggtggcgct cgcacccacc gcgaaggagg tcaccgccac
     4261 ccgccgccgc tacgacctga cggaccagga caccctgagc ttcgtccacg acctcgcggc
     4321 ggtcggccgg ccgctgcaac accacctcgc ggccgagctt cgacgcgtcg gtcggagcta
     4381 ggctactgat ctgccgttca acagcgggtt tcccgctcgt tgcccgcagg caaccaacat
     4441 cggcaggcgg acatctctcc gtgtgaccga ccgactgggg gagacgatga actggtccag
     4501 gctgatgggc gtgatggcag ccggccttgt gctgggcggg tgcgccacgt cggcgagcac
     4561 gaccgaggcg gcgcggagcc ccaaggcgtc cgcgcacgac gcgcacccga ccggcgcaca
     4621 ccggaccgcg ggccacggca agggcgggag cacgtccgac gccaaagccc accacccctt
     4681 gttcaccgtg gtcggcaatc ttgacgcccg ccccggccaa ctggtcgtga cacagctcga
     4741 cggcgtcgcc tgcggccagg gggacgcccc ggtggtcgcc acgtcaccgg ccttccgcgg
     4801 gcccgtacgg ctgcactggc agaacggctc ctgcgggtcc acgtccgccc tggcgatgac
     4861 ggccaagccc ggctcgtacc ccctgtcgat caccgtcgca ggccgcaccg tcgcccgcga
     4921 caagatcaag gtcgtacggt cccggcgccc gtcgctcagc ctcacaccgg tctcggaagt
     4981 ggcccgcccc ggggcgccgg tgtggctgta cttcgacgat ctgtaccccg gtgagcgggg
     5041 cacccacttc accgtacggt cggcagccct gtcgcggacc gtgcgtctcg cccacgaccg
     5101 gcagctcgac ttctacaacc cccggacgtt ccaggcccgg ccccagctca ggcccggcct
     5161 ggcggacggc acgtacacct tcgaactgcg cggcccgcac ggccggcaca tcatggagaa
     5221 gcgcctgacc gtccgcgcgt cccgccccgg cgaccccgac tacctcggca aggcgcacgg
     5281 ccccgatctg tacgagccgg gcacctatgc cgacagcccg caccggcaca gcttccgggt
     5341 cgcccgcggg ggaaaggtcg aggtcatgtg gcacgacgtg aacccggacc cgggcgagga
     5401 gatgcgtctg accgccacct ccccggcgtt cacccacgta ctccacctcc gcgccgacga
     5461 cagcaagtcc gccgacggcg acgacccgcg cttcctcaac acggcgacca tccgcgccga
     5521 cctcgagccg ggccgctatc cggtgacggt cgtcgcccac cacggccgcg tcaagaaggt
     5581 cggctatgtg atcgtgacgg ctcggtaggc ggggtggtcg tggtggcccg agcgtgcttc
     5641 cggccgggcc acctgtcggt caactcccgt tcatgaagcg gtacatgccc accgaatcgt
     5701 gtgcggcggt gtcggcgaaa ccgaacttct cgtagaggtg gcgcgcgggg ccgtccgcga
     5761 tcagagagac gtacgcggtg gcgggcgccc ggctttccag ctcctcggtg agcgcggcca
     5821 tgatgcgctt gccgagacct tgcccctggt gtgcggggtg cacgcagatg tcgacgatct
     5881 ggaacgcggt gccgccgtcc ccgatgatcc gccccatgcc gatgggctcg ccctcgtggt
     5941 ggaggacgac gccgtaccag gtatggggca gggcgagcgc gactgcgtcg ggggcccggt
     6001 cggagaggcc ggcatccgtc cgcaggcggc ggaagacctc gacggagggc acacccgcac
     6061 gcagctcgta agggccactt atgctgtcca tgccttacat ggtagaggtc gccgggtgcg
     6121 gtggggagtg ggggtgacga ggatcctcac ccctcttcgt ccagcgcgaa ggatccgtac
     6181 tcgggtgtgc ccgctcgttc gtaggcgcag tactgcactc ccgcacccgt ggtgcgggat
     6241 tccgtgagcg tccaggcgac gggcgtggcg ccctcgccga agagccgctt gccggtgccg
     6301 atgatcacgg ggttgacgag cagccggtac tcgtcgacga ggtcgtgctg ctgcagggtg
     6361 tggatcaggt cgctgctgcc ctgcgtcatg agcacgccgt cgagttgttc cttgagttgc
     6421 gcgacggact gagcggcctc gcccttcagc aggtgggagt tgtgccactc caggctgtcg
     6481 cgggtgcgcg aggcgacgta cttgggcatg gagttgagct ttacggcgat cgggttgttc
     6541 tcgtcggtga cccggggcca gtgggcggcg aagatgtcgt aggtcttccg gcccagcagg
     6601 agatggtcgg cggtccgctc gaagatcccc gtcatgaggt ccatgaagtc ctcgtcgacg
     6661 tacgggacct gccagccgcc gtgcgggaac cctctgtcga cgtcctcgtt cgggccgccg
     6721 ggggcctgca tcacgccgtc cagggtgacg aacgcggtga cgatcagtct gcccatggtg
     6781 ctgcctttcg ggtacggaat ccgcgtgcac ccggaatgac tcccggggcg gcgagcactc
     6841 ccgccacgta ccaccttggc gcatgcaaca gcggccggct cggcgccatg agcgctgagc
     6901 cggccgcttc ggtgctgcgt cacccggagg acggcgagcg tgctgctcgc cgtccgggct
     6961 ggtcagtccg tttccgtccg ttcagtccgt gccggactcc atggcggcgc ggtccagcca
     7021 ctcgtcgtcg ccggagacct cgccgcggga ggcgatggcc tcggcgccac cctccggcag
     7081 ggagccgatc agcccggtcg cggccgcctg cgcggcgccg acggcggggt tggcggtgcc
     7141 gatcaggccg agcccggcgt actgctccag cttggcgcgg gagtcggcga tgtcgaggtt
     7201 gcgcatggtg agctggccga tccggtccac cgggccgaac gccgagtcct cggtgcgctc
     7261 catggacagc ttgtccgggt ggtagctgaa cgccgggccg gtcgtgtcga ggatcgagta
     7321 gtcctcaccg cgccgcagcc gcagcgtcac ctcgccggtg acggccgcgc cgacccagcg
     7381 ctgcagggac tcgcgcacca tcagcgcctg cgggtccagc caccggccct cgtacatgag
     7441 gcgaccgagc cgccgtccct cgttgtggta ctgggcgagg gtgtcctcgt tgtggatcgc
     7501 gttgaccagg cgctcgtacg cggcgtgcag cagggccatg ccgggcgcct cgtagatgcc
     7561 gcggctcttg gcctcgatga tccggttctc gatctggtcg gacatgccca tgccgtggcg
     7621 gccgccgatg gcgttggcct ccatcaccag gtcgacggcg gtggcgaact ccttgccgtt
     7681 gatcgtcacc gggcggccct ggtcgaagcc gatcgtcacg tcctcggtga ggatctcgac
     7741 cgacgggtcc cagaagcggg cgcccatgat gggctcgacc gtctccacgc ccgtgtcgag
     7801 gtgctccagg gtcttggcct cgtgggtggc gccccagatg ttggcgtcgg tggagtacgc
     7861 cttctcggtg ctgtcgcggt acggcaggtc gtgggcgagc agccactccg acatttcctt
     7921 gcggccgccg agctcggtca cgaagttcgc gtccagccag ggcttgtaga tccgcaggtg
     7981 ggggttggcg agcagaccgt accggtagaa ccgctcgatg tcgttgccct tgaaggtcga
     8041 gccgtcgccc cagatctgaa cgtcgtcctc gagcatcgcc cggaccagga gggtgccggt
     8101 gacggcgcgg ccgagcggcg tggtgttgaa gtacgcccgt ccgcccgagc ggatgtggaa
     8161 cgcgccgcag gtcagcgcgg ccagaccctc ctcgaccagc gccgcgcggc agtcgaccag
     8221 gcgcgcgatc tcggcaccgt aggtcttcgc gcggcccggc accgaggcga tgtcgggctc
     8281 gtcgtactgg ccgatgtcgg cggtgtaggt gcacgggacg gcgcccttgt cacgcatcca
     8341 cgcgactgcg acggaggtgt cgaggccgcc cgagaaggcg atgccgacgc gctcgccggc
     8401 ggggagggag gtgaggacct tggacatgga aagagtatgc agcatctcgc atgatcatgc
     8461 aaagggaatg tggcgtgccg cgcgaagcgg tcactcaaag tgaagttgct ggtacggaag
     8521 cgtgccgaca gtgagcccgg gcgcggccgg caccgcctcg cgcgcccccg tgccggagcg
     8581 gagaatggtg ccctgggccg gtagctccct gccggtcgcg gaggaggtag ccgatgcgcc
     8641 acacccatct gaccggggag tcggagacct acaccgacgc gcgtgaggag ctgcggcagg
     8701 ccgagatcga gctgatgcgc cacccccacc ttccgcgcgc acgcccgcga ccggcagtgg
     8761 acgaacctgc ggctgctgag cgccggttcc agcaccttca agtacgacct cggcagcgag
     8821 gacgccgagg gcaaccagga ctcgacggtg tcggtcttca cccgggacgg caacggggac
     8881 gtgcgccact tctattcggc gcacccccgg atggccgagg acatcgacca gcgcgggatc
     8941 gacctgctct gcccggtgtg gcacttcctc gacctcaccc ggcacggccg gggcgactgg
     9001 ttcgccgcac tcggctacta gacgaacgag acggccgaga agagcgcctt cccgcacggg
     9061 ggctgcaccg cgtgcggcgc agcccccgga gagtcacacc cggtcggccg cgatcagcag
     9121 gtactggaag ctgccgttgc ggtaggcgtt caggaaggtg tcctcgatgc cggtgaccaa
     9181 gtggtcggcc tggcggcgca gttcccagta ggggagtgcg gccgccgtga ggtcctggac
     9241 gtgcacgggg acgagcctgt tgcgggccat ggcgcggaag tacgccgaac gggggtggat
     9301 gtcgcagatg tagtgggcgt tgatgaggga cacctcgcgg gaggcgcgac catacgcgtc
     9361 gttgtagcag ccggtgatca cgacgtagcg gccaccgcgc cgcagcagtc gtgcgtgctc
     9421 cgcgaacagc aggtccagtt cgacgtacat gctcgactcg ttgttccagg acgccgcgta
     9481 cgcgccggag gtgaagccgg tgtcgagcat gttgcggtgg tggtagcgca ccttcgcgtc
     9541 gataccgcgc ttgcgggcct gctcgttggc gaagtcggcc tgtttggcgg agatggtggc
     9601 cccgtcggtg tggcacccgt agcgcaggtg cgcgaccacg ctgccgccgc cgcgaccgca
     9661 gccggcgtcg aagacacggt cggtggggga gaggccgccg aggtgggagg cgaggagttc
     9721 ggcctgggcg tgttccagcc ggtgcagttc gccggtgatc cgctcgcggc ggcggtcggg
     9781 gtccggttcc tccagtacgg accggtcggc gtccccgatg ccgtagtggt ggtggtacag
     9841 gtcgtcgatc ttgccgagtt cgaggttgac cgggttttcc tcggcgttcc agtagtccgc
     9901 gacacgggac tggtacgtgg actgggtcgg caccggtgtg cgtgcggtgt cggcgtgagc
     9961 gatggtcaac ggagctcctt gcggtggtgc gcggatcggt ctaccagtaa ttcggcaggt
    10021 ggtagcggtc ggtgttcgtg gcgtgccact cgtggttgcc ggagacccag tcggccaggc
    10081 tccggacgta cctttcgagg agaggggaga gggcggccag cggggccgac tccgtctcga
    10141 acgcctccat gatctggttg tggatcccga cgctcttgag gtaggcggcc ttgagaccgc
    10201 gtttgtcgtt ggcggccacg acctgcggca ggttcagatg ggtcgggtca ctggccagtt
    10261 ccttggtgaa ggagtacagg tcgttgacga tggtcgtggc gttgcaggcc agagcggtga
    10321 cccgctggac ctcggggcgg gcgtagagcg gttcggggag ttcgtagccg tccacggcgt
    10381 ccacgatgga caggcagggg cggaagttgt tgaactgccg catcaccagg tactcccaga
    10441 cctccggtac gtgccgcgtc tcggcccagg acgcctcggc gagatagccg aggtgcaacc
    10501 gcgccatgtc atggacgaac cggccggtct gactgggggt ggcgaaggcc gcgtagtcct
    10561 tgagggcgca gtggtacgag cgcagcgggc cgtcggcctg cacgccgccg cgccactcct
    10621 cctccgtttc ggcggtgccg tggaacgggt cgagggccga ctgggccatg atcagtcggc
    10681 cgcccaggcc gcggcgtgcg ccgccccggc cttcgtcctc ctcgcagtag cagctgtcga
    10741 cgaggttctc ggccagcagc aactcgcctg cggcggtgag gcgttcgaga tcggccgcac
    10801 cgggatgctg caggacgacg gcccgcccga actggaactg cgtgaagtcc cccgtccact
    10861 gcgcggggaa gaggtccagc cggcgggccc atgcctccag tctgcggtcg acctccttga
    10921 ccttgtccgg gtcggcgggg acggcgggcc ggtaccgcag cccggggacg gctccgccgc
    10981 gtcgggcctg cgaggagcgg gcgaggctcg gcggaccggg caacgcgaac ccggcggagg
    11041 tgttgggggg cgtgctcatg gttcgtactc cacctggtca gtcggtgctc cggccgatct
    11101 ggacgttctc caggactccg gctgcgtcgg gcacgaggat ggccaccgag tagtaggcgg
    11161 tgatgaggta acggatgacc gcggcctggt cgatgcccat gaaacgcacg ttgaggccgg
    11221 gctggaactc ctcggggatg ccggtctggt acaggccgac gacgccctgg tccgcctctc
    11281 cggtgcgcag cgcgatgatg ctgctggtgt tcgtatcgct gatcgggatc ttgccgcacg
    11341 gaaagatcgg gacgccgcgc caggcgggaa cctgatgccc gttgacatcc gccgtacccg
    11401 gtaccagacc gcgcctgttg cactgccgga agaaggcggc gatcgccttc ggatgggcca
    11461 ggaacagccg ggtcttgcga cgcatggcca acaggtcgtc catgtcgtcg ggggtgggcg
    11521 ggccggtgtg ggtgctgatg cgctggccgt agtcggtgtt gtgcagcagt ccgaactccc
    11581 ggttgttgac cagctcccac tcctggcgct cgcggatctc ctccacggtg agccggatct
    11641 gctgctgcgt ctggtccatc gggtcgttgt agagatcggc gacccggctg tgcacccgga
    11701 ggacggtctg ggtcagggag agttcgtact cgcgcggggc gaggtcgtag tcgacgaaac
    11761 cgccggacag cgtcggctcc ccgacgtgcc ccgcctgcac cggcacatcc gcctctccct
    11821 tgcggttcgc ggggagctgc tgccgctccg cgtacgccgc cagatgtgcg gcgagcgacg
    11881 gcacccggtc ggtgaactcc cggatcacgt cccagggaag cgccagcagc acgcccgcgg
    11941 tttcggcccg gaccgagctc tgccaccgag ggtcgggccg gccgatcgcc tcgtcgccca
    12001 tctggtcacc gtccgtgacg acgccgagga cttcctcctc gccgtacttg ccggcggtgt
    12061 agcgggagaa ccggccgtgc acgacgaggt acgcctcggt ggccggctgt cctgcctcga
    12121 agagggtctg gccggcccgg acctcccgga cgcggaaacg gccggcgatc tccttgagga
    12181 cctcgatgtc gtcgtaaccg cgcaggacgg gcagctcggt gagggtctgg gggatcactc
    12241 tgatgtcgtc ggcgccgttc tgctcgaact ggacacggcc ccggccgacc cggagttgca
    12301 gacgccggtt gacccggtag gtgccgccct tgacgtccac ccacggcagc atcttcacca
    12361 gccaccgcga ggtgatggcc tgcatctggg gctcggactt ggtggtggtc gccaactggc
    12421 gcgcggcctg tgtgctgagg ctggtgagcg cactgtctgc gggtggttcg agatcgggct
    12481 cttcggcggc gggaccggtg acgctgtccg gtacggacac tttccctccc gggacgtgaa
    12541 cagaagtgag cagaacggcc ggtggtgagc agggtggccg tgcgcaggaa caacccaaac
    12601 aggaggaaga tcgggtgggt acggcgcgaa agggggcgac gttcgcattc aggagtcaca
    12661 aaccccaaaa cgaggcaaac ggacctcgtc catgcttccg cacgccctcc ggctgccgca
    12721 tgatccagga atacgggcac cgggaacccg tgggcccgca cgcactccgg ccgcccgcag
    12781 ccgtcgcggt acggtgcccg cgatggctgc gggcggcccc gggacgcggc ggcgccgctc
    12841 gtacgggccg cgcagcgcgg cgacgccctc gtcatggacg acctgctcaa gctggtgacg
    12901 ccgtacgtca cgcggctgtg cggcccgatc gccccgcgcg acaccgcgga cgccgtaccg
    12961 gaatcccttc tcgcggtgtt ccggggggct gcgcgggctg cgggatccac atattcggga
    13021 tcatgaggga gtcccttcgt cggatgcgag aagccgcctc atccgccagg aggcggccgc
    13081 ccccgcgaaa gttccctcct ggtgctaggc ctcggcgatg tcctggtcgg ggtcttggcc
    13141 gggggcctgg gcgggggccg tggcgtcggt ggtcttcggc cggccaccgg cgagccgtag
    13201 cgtcacggca gccgcgacgc ccgccagcag gccccaggtc agtgcggccg ggatgccctc
    13261 gccgaggccg gcggccaggt gcagcagccc ccattgcaga cccgtcccgt ccgtcgccat
    13321 ccgcagcagc tggctcgcca gcaggccgag cacggtcgcg cacaccgcgc cgaccgccat
    13381 cgccgggacg gtggcgcggg tgagcagtgc gggcagccgc cgcagggccc accacaccac
    13441 gacgagcagc agtacgtcgg cggcgcgata caggagccag tcgccgagcg gcgtccccgc
    13501 cgggtccgtc caggcaccga acagcagcca ctgccgcagg aggtcgcccg gttcggagag
    13561 cagcccgatg ttcggggaca ccgtctggag ggcggcggcg accgactggt acgagaggac
    13621 catcagggac acggcgatca ccgcggtccc gacggtggcg gccaggcggg ccgcgcgggc
    13681 cgggacttcc gccggcggca gcggagcggt ttccttggcc gtgacccgcg ctgcgaccac
    13741 ggtcaccacc gccgcgacca gcgcggccag caccaggatc tgccgcccgg agccgatcac
    13801 gcctgcgagc cggggcagga agcggaaact gccgtgcccg cccgcggcaa tcatccaggg
    13861 cgcggagacg gccaccgcca gggtcccggc caccacgccc cacgcccacg tcgcgagcag
    13921 tgcggccgcc gtccggccgc ggccgccgcg caccggcggc agcctgcgga ccaggagcag
    13981 cgccccgagc aggaagaagg cgaagaccgc gccgaaccgg atctgcagcg cggtcgtgta
    14041 gagcgagagg tagcgggcac tgtcgaccag ggcttcgccc ccgatcccgc cggacgcctc
    14101 gccattgagc tgggtcgagg acggggggtc gtacgaccag ggggcgagcc agtgctccag
    14161 atcggcggtg gccgggccgc cgatgacgtt ggtggcgccc ggcaggtgca gcgcgtgcgc
    14221 gctcgtcccc gcccaccaga gaagcgccgt gagcaccacc ccgccggcca gtgccggtat
    14281 cgccgcgtgc cgatatgtca tgtgttcccc cgccttggtc acgcaacctg tgaatcccct
    14341 gtgcacgtgg agattacggg gcattgatca cacccggatc acggccgtct ccgcggatca
    14401 ggggcgtatc cgatggcggg aggtgagcac acgcgcacag cgttgcggta cttgttgccg
    14461 ttgccgttgc cgttgccgtt gccgttgccg ttgtggttag aaggacccca ggtcggcgga
    14521 cacccagtgt tccggctgca gatagatgac gacgtgcgca ccgagctggg cctggtcgaa
    14581 ttccacgaag tcggcgacct tgtcctgggg gaggtaccgc gcggccatct cccaggaccg
    14641 ctcgcggctg tccggttccg tcctgatcac cggcccctcc accgacacgt agcgcaccgt
    14701 cggctcggtc cgctgcacca tgaggctgaa acgccccgca gcccgaatcg ctcgtgcctt
    14761 ccgggaatca ggcccggtgc gcacccacag ctcgccgccc ggcgtgtact ggtaccagat
    14821 ggggaccgtc agcggtgcgc ggtccggccg ctcgaccact gacagcgcac cgatgtgagg
    14881 ttccgccaga aactgttcgc gttctcctat cgacaaggtc atggggccga ccatagtccg
    14941 gccgacgact cccggccgtt cttttcgggg cgtgggtcga accggttgct gccccggcgt
    15001 tccccttgcc gtcggggcgc tgtgccgtca gctgctgccg gcgcgccggg cggggaaccc
    15061 gtgtgcccgg gcggccagta cgacgacgag gacggggacg agcagggtca ggacggtcca
    15121 ggggaaggcg tcggccccga cggcctgcag gaggaggccg ccgatgatgc cgccggcggc
    15181 catggcggcg ttccacaggg tcaccagcat ggcctgggcc gcgtcggccg cctctccacc
    15241 ggcttggccc gcggcagtct gcaacagggt gggaatgccg ccccagccca ggccccacag
    15301 ggcggcggcg acgtacacca gcgcgtggct gccggagaag gcgcccagga ccgcggcggc
    15361 gacgccgacc agcacggcgc cggcgagggt caaggtgcgc aagtggccgt ggatgaaggt
    15421 gccgacgatc cagatgctcg ccagcgaggc gatgccgaag accagcagag ccgcgtcggt
    15481 ctggtcgccg aggccgatgt ggcggaggaa ggtggcgatg taggcgtaga ggattgtgtg
    15541 cgccaggacg aagacgaggg tgacgaacag caccggggcc acacccggga cgcgcagggg
    15601 ccggcgcatc gggagcttgc cgccggcctt ctggcccggg tagtcgggca ccgcgacggc
    15661 gatccagacc agcaacacca gggtcagggc ggtcatggcg aggaaggcgg cctgccagga
    15721 gaccacttgg cccaggaagg tgccggccgg gacgcccagg gacagcgcga cggggatgcc
    15781 cgccatggcg atcgcgatgg cgcggccctc ctggtggggg gcgaccatcc ggcgggcgta
    15841 gccggccagc agggcccagg ccagcccggc ggcgacaccg gcgacgaacc gggcgacgag
    15901 ggtcagtggg tagttcgccg accatgcggt gacggtgttg gcgacggcga agccggccat
    15961 ggccgtcagc agcaggcgct tgcgccgcca gccggcggtg gccgcggaca gcgggatggc
    16021 cgtgagcacc gtgcccagcg cgtagatggt caccgtctgg ccggtggccg actcgctcgt
    16081 gtgcaggccg gcgctcatcg cgggcagcag cccggccggc agggtctcgg tgaggctggt
    16141 gatgaacacc gcgatggcca gcgcgagcag cgcccccatc ggcagttttt tgtggagagt
    16201 tgatgtcccg tcaggaaggt gggccgagga tatggcggtg tctgtgggca gctcagtgct
    16261 tcgcatgagg ggatgctgaa accttcccat aagtgtgaag gtcaagtccg gcttgcctgc
    16321 gggtggatcc cgtgcctctg gggctgcctc tccttcgcat ccgcatctcg atcaaccgtg
    16381 cgagaggtgg ttacgatctc gcccatgacc aagctcttca cgcaccggct gcgggtgcgc
    16441 tacagcgaat gcgaccagca gaacgtggtg ttcaacggcc actacctctt ctattacgac
    16501 gtcgccgtca cggagttgtg gcgcgaagcc gcggggggct atgcgtccat gctggcgggg
    16561 ggtgccgatc tggtggtggc agaagcgcgg attcgctatc gccagggggc acgtttcgat
    16621 gaggtgctcg acatcgagat gcccgtcacc catctcggaa cgacgagcat gatcgtgtgc
    16681 ccgagattca aggtcggcga acggctcatc gcggacggcg aggtgcggca tgtgttcacc
    16741 gacgccgtgg ccggcggcaa gagggagatg cccggcgtca tccgggaagc cttccagccc
    16801 tacctctcgg caggcgaata gcgcccgccc gggcgccagt tggcgttacc cggacattgc
    16861 ccgctcctca gccttgcccg tgcgcagtcc ggtcacggcc tgcacgctct gtccgaatac
    16921 tccacaaaag gtgcgagatt tgatcgagcc tccgcgggtt agcttcctct cgtcgcctga
    16981 ccgcccgccg ttgcggccgc ggctcctttt caggcgcgaa gtcgatgggg ggaaccatgg
    17041 acatcgcact tccgaccgac gacaccggtg gccctgacca ctgctgtgtg tttctctccg
    17101 acaacaggac cggcggcccc gtttccgggg cgctggcctt cctcgaagcc cagttgaccg
    17161 tttccgagga gggctccggc ggtgaggtgg gggctgccgc ccgcgcaggg caatcggtcc
    17221 gcatcccgct ggggctgctc ggcagtgacc acgccgggta cctctcgtgg gacctggcgc
    17281 cgctgtggcg gcaggtcctg caactggagg agcgacccga cggctccacc gccgaggtgc
    17341 gggtcgccca cgtgtggctg tacctcggcg gtccgctgca gagcgcggtg gacgtcctgg
    17401 ccgaggccga cgagcgggcg caggccctgg tcctgcggct cggcgtggat cgcggcggcg
    17461 tcttcaccgg ctcgaccagc ggctttcccg cgatgcagtc gccctcgctc ctcgactggt
    17521 acctctcgcc gggctcgttc gcgtacgtac cggccgaact catcggtcag gacggctgcg
    17581 agaccctgct gccgtccaat gtggccaccc agcagtacca ggtgcaccag atcgtgaccg
    17641 tcccggatct catggcgagc ctggattacg gcgctcagta cacggccccg gccggggacg
    17701 gaagcggaac gtcggaccac tccgccccct ccgaccgatc cgacggctcc cacccttccc
    17761 acagctccca ccgcctcgcc ggctttccgg tgcccgtcgc cctcgtcatc agttacgacg
    17821 tcacctggct cccggtgggg cacgggctcg ggcaggtcac ctacagcctc ccgctggcgc
    17881 cgggcgagca ggtgcagctc gcggtcgtgg actggtcgcg cacctcgacg gacagtcggc
    17941 tggaggacat cgccctcacg gacgaccttg agcatgccct cacccgtgac cggaccgtcg
    18001 acgaggtggt gaagggcgcc gtcaacgagt ggcagcgcgg cggctcggtg atgaccggtg
    18061 cggcgggcgc ggcgtcgatg ggcatgttcg gcggctccgc cgcgatcggc ggcgggtacg
    18121 ccacgacatc cggggaccgg agcgtgtcgg cggacaccgt gcagaacctg cacgaccaga
    18181 tccgccagca ctccacctcc gtacgcgaca tgcgcagcac ggtggtggtg cagtcgcgcc
    18241 aggcggagaa ctccaccgcg cagacccgga ccgtacgcaa ccacaaccac gcgcatgcca
    18301 tgaccctgct ctactacgag gtgttgcggc acttccgggt gctcgtcgag cgcggcaggg
    18361 tgcgccgggc cgtcctgctg ccggccgcat ccccggacct cgatgacgag ctggtcatcg
    18421 tccgctaccg ccgcctgctg caggccgggc tgctcgatcc gcaactggcc ggcggattcg
    18481 acgcggtgga gaagtacgcc gcctggcggg aactccagcc cgaggtgccg gtgccgcccg
    18541 atccgggcag cgtggaattc atcctcttcc agttccgctt caccatcggt gacctgtcca
    18601 gtttccagga ccgggtgccc acgaccgtca ccctgaccca gcgagcgccg gacggcggcc
    18661 agaaagtcac cggtctgatc cgtccgcagc acagtgactg ggaccccgat ccaacccatc
    18721 tgcagaaccc cggcgacttc cagcacaccc acgccgtggt ggatctcgcc ggtgtgccca
    18781 gggccgacga gcgcgtcaac tggcgtgatc tgcggacgat ttcggtgacc ctcatcccgc
    18841 cccacaccga aggccggaac gacgacgtcg ccgtggagca cctggtcgtc acggccgtgg
    18901 acaccgcggg caacacccac ctcctggtcg acgagcccag cggcaagctg ttccagaagc
    18961 cgtccacgac ctgggcgctg gcggcccggc aggcaccgga acccgcgccc gcgccgaccc
    19021 cgttccaacg gctcagcgat gacgagaacc tgctgcggat ccggctgcgc agacacctgg
    19081 tgcagaaccg cgagcactac taccgactga tccggctcgg cgaggacccc aacgcccgct
    19141 ggaccgaact ggcgggcagc accctcaccg tcggcggcac cacgcgcccg ctgttccagg
    19201 ccgtcgagaa ccgcgcactg gaagtgctcg gggacgccac ggccttcccg ctcgaccccg
    19261 cgctgttcga cggcgcgggg gaggggcagg tacggcttcc ggaggtggac cccgcccgca
    19321 gcgagcagtt ggtcagcctg cccacccgcg gcgtcttcgc cgaggccaaa ctcggccact
    19381 gcaattccgc ggaggtcatc gacaacaccc ggttctggga ctggcagaag tcacccgatc
    19441 cggacagtgc cccgcagatc gctccggtgt ccacggcgag ccgggaggtg gtcgtcgcca
    19501 cgacgccctc ggggctgccc acctcggcgg tcaccatcgt ccagccgccg caggcccccg
    19561 atcccgtggg cttggcggca gccctccaac tcctcggcaa gggcgacatc ttccgcgacg
    19621 agtcgatgca gaaggagatc gccgccctgc tgacctcact ggcgagcgac gcggccggtc
    19681 tcgccggcaa gacccccggc acgcccggca caccgggtac gcccggcacc ggctcgacac
    19741 cgggtacggg aacgggcggc ggcccgggaa caggcactcc cggcacggga accggccccg
    19801 gcgccccgac cggcggcggc accgggaccc cgggcggcgg tacgccgggc ggaggcaacg
    19861 gcaccggagg cggcacaccc ccagggagtg gcgggacgcc cgccaatccc ggcggcaccc
    19921 ccgggacgac gggacccggc acacaacccg gctccggcga cggcggccca ggcacaccga
    19981 agccccccgc tccggcgccg caccccacac cacggccgcc cgtgcccatc ggctcggaca
    20041 accggtcgtt cgtcttcagc ttcgccccgg tcagtttcgg ccccagcgag gcggactggg
    20101 agcgcggcag gttcgccatc gcgatcttcc aggacggcaa gccggtgctc agccaggaca
    20161 acgtcgagcc cgcggcgccc agcgtcatcc tcaacggcag ggtcgccccg gacaaaccgc
    20221 tggacatcgt ggtcgacggc tcgtccaccc actgggtgac ctacccctcg atctactcct
    20281 ccgccatggc gggtaacccg tccaccctcg gaacgccgcc cggcatcctg atcaccacgc
    20341 atctggtcgg caagctgacg ctcgccgggc tggatccgaa gcagcgcagt catgtcttct
    20401 cgatccgacg cgacgtcaag ttcacctcgg tgacgctgag cgagcagcag attcggcaac
    20461 agggcctgga gaaggtggtg tcgggccaga tcaacgccag cttcgacaag gtcatttcgt
    20521 tcggcgcggg actcagctcg tccgagacct cctcgaccag cacggggacg accaccaaca
    20581 agaccgacac cgtgcccgtc acgttcttca ccggactgat gtccatcagc cccgtcaaga
    20641 actgagccca ccaggcggag atctgacgag gcgctacgta ccaggtcggg ggtcgagggg
    20701 cgcatccccc ggccctcgac ccggaccggc ccccgatcct gaacggggaa ccgtgcagcc
    20761 gtgcccgtct cgcccaagct cggcacgtcg cccaggcggc ggaccagtca gttctccatg
    20821 gcatgtgaca ggaacaagta cccatcactg accggttgtt ggagtgctcg ggccgggcat
    20881 ccggagcgct tgtgaagatc gggcgcggcg acgatttctg ctcccgttta cggcttgccc
    20941 aggcgggaca gcccctatgc tgtgacctcg caatgactct acgtgttgag ttttggggga
    21001 actgtgaaga gggcagcgtt agcactgctt gcctgtgggc tcggctcggt gctcttggt
//
