LOCUS       NZ_AP026073            20924 bp    DNA     linear   CON 31-DEC-2024
DEFINITION  Streptomyces nigrescens strain HEK616 chromosome.
ACCESSION   NZ_AP026073
VERSION     NZ_AP026073.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces nigrescens
  ORGANISM  Streptomyces nigrescens
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Asamizu,S. and Onaka,H.
  TITLE     Complete genome sequence of Streptomyces nigrescens HEK616
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8253039)
  AUTHORS   Asamizu,S. and Onaka,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2022) Contact:Shumpei Asamizu The University of
            Tokyo, Graduate School of Agricultural and Life Sciences; Yayoi
            1-1-1, Bunkyo, Tokyo 113-8657, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: HGAP4 v. 4.0; Falcon v. 0.3; Canu v. 0.7; Arrow
            v. 2.3.3; Pilon v. 1.22
            Genome Coverage                   :: 262x
            Sequencing Technology             :: illumina Hiseq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024349765.1-RS_2024_12_31
            Annotation Date                   :: 12/31/2024 04:23:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,326
            CDSs (total)                      :: 8,236
            Genes (coding)                    :: 8,032
            CDSs (with protein)               :: 8,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 204
            CDSs (without protein)            :: 204
            Pseudo Genes (ambiguous residues) :: 0 of 204
            Pseudo Genes (frameshifted)       :: 84 of 204
            Pseudo Genes (incomplete)         :: 166 of 204
            Pseudo Genes (internal stop)      :: 16 of 204
            Pseudo Genes (multiple problems)  :: 56 of 204
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:47:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7273756
            Orig. end                         :: 7294680
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP026073.1.
            Annotated by DFAST https://dfast.ddbj.nig.ac.jp/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20924
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="linaridin"
                     /region_number="24"
                     /rules="(cypemycin or cypI)"
                     /tool="antismash"
     cand_cluster    1..20924
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cypemycin or cypI)"
                     /kind="single"
                     /product="linaridin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20924
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10924](+)"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10924
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
     gene            complement(1446..3035)
                     /gene="dacB"
                     /locus_tag="HEK616_RS32305"
                     /old_locus_tag="HEK616_65930"
     CDS             complement(1446..3035)
                     /EC_number="3.4.16.4"
                     /GO_function="GO:0004175 - endopeptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="dacB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604047.1"
                     /locus_tag="HEK616_RS32305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_65930"
                     /product="D-alanyl-D-alanine
                     carboxypeptidase/D-alanyl-D-alanine-endopeptidase"
                     /protein_id="WP_261957504.1"
                     /transl_table=11
                     /translation="MPETRKWQVRWQSAQRSAQRTAREAADAAGRSARAAAGTVRQAWQ
                     DTPRHTRQTWRLTAVSAATGLTAALVAVAAAGPWDSGQRTAERAEAAVVDGSSGEHHAA
                     EPDRPAPSAAPVLPALGVRPAAGAGRGAAPVPTGAGLADALAPLLKDPALGPLRTASVV
                     DVAAGREVFGSGQGKAATPASTVKLATAVAALSARGPEHRIDTTVVTAGKDRIVLVGGG
                     DPTLTARAPQQTTAEQPASLRTLADATARALKRRHLTTVGLGYDASAYSGPVDHAFGPD
                     ENLAPVTALMTDEARLDDSDHGPAPRDADPAGTTARTFADLLHERGITIDGTPKGAKAP
                     AHAERLAAVHSLPLSSLVERMLTYSDNDIAEALARQAALGSGQPASFAGAAKAVHDALA
                     RQHLPLAGAVFKDGSGLDRGDKVSAALLSRLLLQAAAPDHPALRSVVTGLPVAAFTGTL
                     SSRYTGQSAGAGAVRAKTGTLTGVNTLAGTVVDADGRLLVFSFMTTGTTDAPGAQRALD
                     NLASAVANCGCR"
     gene            3122..3613
                     /locus_tag="HEK616_RS32310"
                     /old_locus_tag="HEK616_65940"
     CDS             3122..3613
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142076.1"
                     /locus_tag="HEK616_RS32310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_65940"
                     /product="inorganic diphosphatase"
                     /protein_id="WP_261957505.1"
                     /transl_table=11
                     /translation="MEFDVTIEIPKGSRNKYEVDHETGRIRLDRRLFTSTSYPADYGFV
                     ENTLGEDGDPLDALVILDEPTFPGCLIKCRAIGMFRMTDEAGGDDKLLCVPASDPRVEH
                     LRDIHHVSEFDRLEIQHFFEVYKDLEPGKSVEGANWVGRAEAEAEIEASYKRAEAHGGH
                     "
     misc_feature    complement(3999..4014)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.04"
                     /tool="antismash"
     gene            4030..5973
                     /locus_tag="HEK616_RS32315"
                     /old_locus_tag="HEK616_65950"
     CDS             4030..5973
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435956.1"
                     /locus_tag="HEK616_RS32315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_65950"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_261956398.1"
                     /transl_table=11
                     /translation="MAHRVGRASQRGRTTRAGLVATVFRQHTALLVAGVALGLAGVAAS
                     LTQPVAIGRLIEAAGRGESLGAPITWLVSLFCAGALLTSLQAYVIGRAGENIVFDVRRL
                     LTERLLRADLTAFGKRPQGDIFTRTVTDTSLVKIALSQSLTQLITSGVTVLGGVVLMFC
                     IDAGLMVITLGCLGAASVVSLLLARKLRKVALENRDDIGAFGTAVQRVLSALPTVKASR
                     AESREADRIGALAGNARRSGIRGTAYGALLTPSMNVGTQGALAVVVGVGMAWVARGEMT
                     MAALTTFIMYLFQLVSPLVMFFMAVGQFVQGRAAIQKVDELADMPQEGGGTADAGRAAP
                     MVLAAHGRAAVEFRDVRFGYERGDQGERSPVLHGVSFHVPARGLTAVVGPSGAGKTTLF
                     QLIERFYPASGGSILVGGRNIEALPLDALRGLVGYVQQDSAALRGTVRENLTYASPDAG
                     EDDIRQAVEMAGLAKVVAKLPQGLDTELGDQGSGLSGGQRQRLCIARTLLQKPAVMLLD
                     EATSHLDSDSERDFRDVLQRVSRHCAVIAIAHRISTVIDAEQIVVLEDGRVRATGRHQD
                     LMTRDALYRRLAGSQLHADSGGRAPARVPDRNHPRDSETTLSLSLAFGGLPPATLNEQT
                     IRLRPIRSEEQW"
     gene            5970..7454
                     /locus_tag="HEK616_RS32320"
                     /old_locus_tag="HEK616_65960"
     CDS             5970..7454
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135440.1"
                     /locus_tag="HEK616_RS32320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_65960"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_261956399.1"
                     /transl_table=11
                     /translation="MNGTDVAVVGTGPNGLAAGVVLARAGLRVALYERAETIGGGLRTA
                     PLFDSGVPHDLCSAVHPMAAASPFFRAFGLAERGVELLQPEIAYAHPLDGGRAALAYRS
                     LAETCAHLGADGPRWRRLMEPLLEHSDGIVDLVMNGQRRLPGDPAAALLLASRVAVHGT
                     GLGAAHFAGEEAAALLTGVAAHAVGKLPSLAGGAVAMLLGHLAHGTGWPLPRGGSARIA
                     EVLAADITAHGGVFHTGHEVTDLDQLGGARAVLLDTSPKNFLALAGDRLPRPYARGLAR
                     FRYGPGAAKVDFLVSEPIPWTDPAVGRAGSVHLGGTRAEIVRQETATARRIRTREPFVL
                     VVDPAATDPGRALPGKRPVWAYAHVPNGDPTDPFELVRARIERYAPGFGDTVLAHRSVA
                     AASYETYNPNYVGGDIGTGAMTLYQSIARPVPRLDPYRTPLPGVFLCSSATPPGPGVHG
                     MSGYFAALSALRHCFGIRTAADVSLSPTPRQFSPAN"
     misc_feature    7516..7529
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     misc_feature    complement(7563..7579)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.41"
                     /tool="antismash"
     gene            7765..8526
                     /locus_tag="HEK616_RS32325"
                     /old_locus_tag="HEK616_65970"
     CDS             7765..8526
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991976.1"
                     /locus_tag="HEK616_RS32325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_65970"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_261956400.1"
                     /transl_table=11
                     /translation="MENGVQDIGYGRQFAGWYDRLLPDDAITAAAVEGLAALHPDPEGG
                     TLEFGVGTGRIALPLSEKIGHITGVDSSPEMLDALRVKLTDGAGDVTPVHGDIRTYTSE
                     SRYSLVYCVCATLSVLTTPEDQQQAVRRAADLLAPGGRLVIETHNKPPVVALHEGLSRT
                     TYFMPHPEPGSGVQTHSTLLDGGLWHCSHILYQADGTTRVGSELTRLTTPEDIDGYARA
                     AGLTPESHLAHWDGSPYSERAPMFICCYVKP"
     misc_feature    complement(7767..7781)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            8567..8914
                     /locus_tag="HEK616_RS32330"
                     /old_locus_tag="HEK616_65980"
     CDS             8567..8914
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604052.1"
                     /locus_tag="HEK616_RS32330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_65980"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_261956401.1"
                     /transl_table=11
                     /translation="MGRPPILPADKKFALVLRVVTGELTAAEAAREAGVSEQSVSNWRR
                     QFIEGGRNGLAGESGKTSENASRIAELTQEIANLKATIGELYMELRKHSRGAGIRVPLP
                     RGRTHPAQRVN"
     misc_feature    8917..8926
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.63"
                     /tool="antismash"
     gene            8988..10004
                     /locus_tag="HEK616_RS32335"
                     /old_locus_tag="HEK616_65990"
     CDS             8988..10004
                     /NRPS_PKS="Domain: Abhydrolase_1 (61-183). E-value:
                     7.8e-13. Score: 40.5. Matches aSDomain:
                     nrpspksdomains_HEK616_RS32335_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991978.1"
                     /locus_tag="HEK616_RS32335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_65990"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_261956402.1"
                     /sec_met_domain="PF00561 (E-value: 7e-09, bitscore: 34.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.7e-13, bitscore:
                     49.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASLERQFAVGLAGLAGASLLTGAVTRFTGGRERARRYLLHERPD
                     GGLVEVAVHIPPQARRVVLLDNGLGAPHEYWDWVCDALPDDMGYVRFNRPGYGLSTPVT
                     QYGLHRHFELLQELRDTYIADLPVVLAGHSLGGYFVAAYASRHPGALKGVTAVVMIDAT
                     EVISLRHSRRTNVDRWARQSLVMEQVYAWAGLSAFRPAKNVNKQYRPQINRSYTAFMTH
                     PRAWATARQEYLDAMTFPELTDLDCPLTVVTAENNVGDNATHHAVQARLAAISKRSRHH
                     FIDGSDHESVLAVPAHAAQVAEVIAGEPPSGTGPEREKSVKDRPAGRRAAEREEELA"
     aSDomain        9171..9536
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEK616_RS32335_Abhydrolase_1.1"
                     /evalue="7.80E-13"
                     /label="HEK616_RS32335_Abhydrolase_1.1"
                     /locus_tag="HEK616_RS32335"
                     /protein_end="183"
                     /protein_start="61"
                     /score="40.5"
                     /tool="antismash"
                     /translation="VVLLDNGLGAPHEYWDWVCDALPDDMGYVRFNRPGYGLSTPVTQY
                     GLHRHFELLQELRDTYIADLPVVLAGHSLGGYFVAAYASRHPGALKGVTAVVMIDATEV
                     ISLRHSRRTNVDRWARQS"
     CDS_motif       9366..9401
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEK616_RS32335_0001"
                     /evalue="6.00E-04"
                     /label="NRPS-te1"
                     /locus_tag="HEK616_RS32335"
                     /protein_end="138"
                     /protein_start="126"
                     /score="12.4"
                     /tool="antismash"
                     /translation="PVVLAGHSLGGY"
     gene            10001..10597
                     /locus_tag="HEK616_RS32340"
                     /old_locus_tag="HEK616_66000"
     CDS             10001..10597
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604050.1"
                     /locus_tag="HEK616_RS32340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_66000"
                     /product="hypothetical protein"
                     /protein_id="WP_261956403.1"
                     /sec_met_domain="cypI (E-value: 7.5e-28, bitscore: 96.3,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVKVNTERVKTVAVTASLAAWLVATAAGQLPENRFDNLLRRGRW
                     QIPVPNWRFFGPNPGVKDNHLLYRDIVDGEPGEWEEVPITRDRPWYALAWNARNRSPKA
                     LFDASQDTIGRSVAFGPELHLVTLGSGYRLLSRYIQRHLPHAEGASHSQFMLMQSFLKA
                     PGDREIEPVFVSLQFPLNDHASDATPEAAAFPVAA"
     misc_feature    10703..10716
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.7"
                     /tool="antismash"
     gene            10727..10924
                     /locus_tag="HEK616_RS32345"
                     /old_locus_tag="HEK616_66010"
     CDS             10727..10924
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypemycin"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033402.1"
                     /locus_tag="HEK616_RS32345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_66010"
                     /product="linaridin family RiPP"
                     /protein_id="WP_261956404.1"
                     /sec_met_domain="cypemycin (E-value: 6.4e-13, bitscore:
                     47.6, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVVAEFANTNLMDVQPGRIGSDAAPTMMTPLATVATPEAVSAGI
                     AVTCATAIALNQVTHNVQHG"
     gene            11069..11947
                     /locus_tag="HEK616_RS32350"
                     /old_locus_tag="HEK616_66020"
     CDS             11069..11947
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604049.1"
                     /locus_tag="HEK616_RS32350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_66020"
                     /product="hypothetical protein"
                     /protein_id="WP_261956405.1"
                     /transl_table=11
                     /translation="MFLDAPPEVTARRVASLGTLVSALEMLSQTRKFEDGELLSGQLAN
                     MRPKFAKRFPRLTRALSSKKAAVALYGVQAGASAATLIWGHKRGVRTAGSAVLAVTGAA
                     GRLHTPFGGDGADQLQQVINVVLASTGTFKDGEKARDVAMRAMALETTISYVASGVVKL
                     VSPVWLSGEAFSGVIRTHNYGDPRIFQLVHKYPMLGKLITWGTVAAEVGFPLVFVLPKP
                     AAKAWLGSMTLFHLGIGQFMGLNRFVLAFGATHPALLYVLAQNEKPALADGAKRALACG
                     AKRALPAASAA"
     gene            complement(12012..13790)
                     /locus_tag="HEK616_RS32355"
                     /old_locus_tag="HEK616_66030"
     CDS             complement(12012..13790)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090093.1"
                     /locus_tag="HEK616_RS32355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_66030"
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="WP_261956406.1"
                     /transl_table=11
                     /translation="MASDPQRGQRNSNGKSGDSDGGPRGGRGGAGHEAAGEERKPASDE
                     AHSAFTPPLGVPYPPLPEDEHPTSEFALPAGLRPEPPAEQEGSAFTPPAGTTTGQTPLP
                     TPVGATAMGLAFTPPHGIPTVRLTKEAPWQDRMRTMLRMPVGERPVPERRERGDEETGP
                     AVPRVLDLTLRIGEILLAGGEGAEDVEAAMFGVAHAYGLERVEPTVTFTLLSISYQPSL
                     VDDPVTASRTVRRRGVDYNRLSAVFRLVDEIASEGITLEEAYRGLAEIRRNRHPYPSWA
                     LTVASGLLSGAASMLVGGGSLVFLAAAVGSMLGDRLAWLASGRGLPEFYQFVVAAMPPA
                     AVGLAFGLAHSSVQASAVITGGLFALIPGRALVAGVHDGLTGYYITAAARLLEVGYLIV
                     GIVVGVLSVLYIGLQVNPGLKRLNPEQALGAYNEPLVQTLASMLLALAFCVLLQQERHT
                     VAFATLNGGVAWVVYGALANVAGINPVPATAIAAGLVGLFGQLLSRYRYASALPYVTAA
                     IGPLLPGSATYFGLLNFAQGHLPQGLTSLVQAASLALAIAVGVNLGSEVARLFLRAPGL
                     LEAGAGRRAAKRTRGF"
     gene            complement(14041..14751)
                     /locus_tag="HEK616_RS32360"
                     /old_locus_tag="HEK616_66040"
     CDS             complement(14041..14751)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018551196.1"
                     /locus_tag="HEK616_RS32360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_66040"
                     /product="DedA family protein"
                     /protein_id="WP_261956407.1"
                     /transl_table=11
                     /translation="MNTLALGPQWLDPDYLIATFGLIGVLVIVFAESGLLIGFFLPGDA
                     LLFTTGLLVTTNKITQPLWVVCVLIVLAAVLGDQAGYLFGRKVGPSLFKRPDSKLFKQE
                     NVVKGHEFFEKYGPKSLILARFVPIVRTFTPIIAGVSRMNYRPFITFNLIGGALWGAGV
                     TLMGSLLGNIAFVHKNIEMILIAIVLISVVPIVIEFLRARGKAKKEAPAAPAGPRPHGA
                     SPAEPARRGRHAKR"
     gene            14989..15357
                     /locus_tag="HEK616_RS32365"
                     /old_locus_tag="HEK616_66050"
     CDS             14989..15357
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604058.1"
                     /locus_tag="HEK616_RS32365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_66050"
                     /product="YbjQ family protein"
                     /protein_id="WP_261956408.1"
                     /transl_table=11
                     /translation="MGIEDYGGGQHAQADVLVVTTNDVPGFHVERVIGEVFGLTVRSRH
                     LGSQIGAGLKSLVGGELRGLTKTLVETRNQAMERLIEQARSRGANAVLMFRFDVTEAAD
                     VGTEVCAYGTAVVIAPMA"
     gene            complement(15447..16205)
                     /locus_tag="HEK616_RS32370"
                     /old_locus_tag="HEK616_66060"
     CDS             complement(15447..16205)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020397733.1"
                     /locus_tag="HEK616_RS32370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_66060"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_261956409.1"
                     /transl_table=11
                     /translation="MSYSVGQVAAFAGVTVRTLHHYDEIGLLHPGERNHAGHRRYGDDD
                     LDRLQQILFYRELGFPLDDVAALLDDPGADPQEHLRRQHDLLTARIGKLQEMAEAVEHA
                     MEARRMNVRLTPEEKFEVFGDFDPDAYAAEAEERWGGTDGYKETQRRTAAYTKEDWKRL
                     TAEFDAIHRRMADLLAEGVPADSEAAMDVAEEHRRFIGRSYYACSHETHTGLGEMYVAD
                     ERFTATYEAIRPGLAVYMRDAMLANAVRHL"
     gene            16320..17036
                     /gene="leuE"
                     /locus_tag="HEK616_RS32375"
                     /old_locus_tag="HEK616_66070"
     CDS             16320..17036
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="leuE"
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536456.1"
                     /locus_tag="HEK616_RS32375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_66070"
                     /product="leucine efflux protein LeuE"
                     /protein_id="WP_261956410.1"
                     /transl_table=11
                     /translation="MLGITDLSTYLVGLALIILLPGPNSLYVVSVAARRGPRVAYRAAA
                     GVLCGDTVLMTLSAGGVASLLQASPVLFGIVKFAGAGYLTWLAVGMLRGAWALWRGREA
                     RKATRDAETPEAAGAAPSASAASSASSASRKEAAERPYRRALIVSLLNPKAILFFISFF
                     VQFVDPAYAHPVLSFLTLGAWAQLFSFTYLSILIFSGTYLAATFRRRRRLTAGLSAGAG
                     AAFLGFAAKLSLASAS"
     gene            complement(17057..17272)
                     /locus_tag="HEK616_RS32380"
                     /old_locus_tag="HEK616_66080"
     CDS             complement(17057..17272)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672342.1"
                     /locus_tag="HEK616_RS32380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_66080"
                     /product="hypothetical protein"
                     /protein_id="WP_261956411.1"
                     /transl_table=11
                     /translation="MLSHFPHDQDVHDCTEALRTALRAHDITLPSLGVDLPGLAGSYAL
                     PLVALGSCNTETARRLTDALHRAAAR"
     gene            17390..18247
                     /locus_tag="HEK616_RS32385"
                     /old_locus_tag="HEK616_66090"
     CDS             17390..18247
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540428.1"
                     /locus_tag="HEK616_RS32385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_66090"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_261956412.1"
                     /transl_table=11
                     /translation="MPPRKDPDGSVSVPCFYGAELRYKREEAGLTLEQLVEGSYRGVSF
                     LSQIERGERRMPEDLARHVDQKLGTDGFFERRCEDARKARQVGHPSYYADIPEMEKAAA
                     TIEDWAPYVVPGLLQTEPYVRELIRAVKPWEPAAAADKTVRARLARARLWQQEERPTYW
                     AILRESLIRNPLLPPAQMADQLEHIAEVMHSTQSVLQILPETTVGHPLMTGGLAKIMTF
                     ADAPPVVWVEADFSGEALDFPPLVAAYRKSYDRLRAAALPPEASLAMIEDAARGYRNEA
                     QKRN"
     gene            18225..18521
                     /locus_tag="HEK616_RS32390"
                     /old_locus_tag="HEK616_66100"
     CDS             18225..18521
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538701.1"
                     /locus_tag="HEK616_RS32390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_66100"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_261956413.1"
                     /transl_table=11
                     /translation="MKRRRGIDLSSATWRKSSYSNGDGADCLEVAEDFIGAAHWRKSSH
                     SNPDGANCLEVRDDLPGLVPVRDSKDPHGPALVFAAPHWSAFVDAVKNGTLGA"
     misc_feature    18581..18599
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.44"
                     /tool="antismash"
     gene            18595..19224
                     /gene="wrbA"
                     /locus_tag="HEK616_RS32395"
                     /old_locus_tag="HEK616_66110"
     CDS             18595..19224
                     /EC_number="1.6.5.2"
                     /GO_function="GO:0003955 - NAD(P)H dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /gene="wrbA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090088.1"
                     /locus_tag="HEK616_RS32395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_66110"
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="WP_261956414.1"
                     /transl_table=11
                     /translation="MHLPAHDVHVAVIYYSSTGTIATLAQWIADAAEHAGADVRLRRTA
                     ELAPQTAVDANPAWAANAEATADILEATHEDMLWADAVIFGTPTRFGNVSAQLKEYLDT
                     LGGLWHQGRLADKVYSGFTASATRHGGQESTLLALYQTVHHFGGILVTPGYTDPAKYRD
                     GNPYGTSHVGGPETPLDEDARTAARIQAQRVVKFTKAIKHGLAPAT"
     gene            19241..20656
                     /locus_tag="HEK616_RS32400"
                     /old_locus_tag="HEK616_66120"
     CDS             19241..20656
                     /EC_number="4.1.1.15"
                     /GO_function="GO:0004351 - glutamate decarboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0006540 - gamma-aminobutyrate shunt
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674102.1"
                     /locus_tag="HEK616_RS32400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_66120"
                     /product="glutamate decarboxylase"
                     /protein_id="WP_261956415.1"
                     /transl_table=11
                     /translation="MTLHKGASASDRKRTARPVNPFYGEADPVSGMEESPPHNILPDGP
                     VSPHTAYQFVHDELMLDGNARLNLATFVTTWMEPQAGVLMAECRDKNMIDKDEYPRTAE
                     LERRCVAMLADLWHAPDPSAAVGCSTTGSSEAGMLAGMALKRRWMRRNADRYPSSARPN
                     LVMGANVQVCWDKFCNFWEVEPRLVPMEGDRFHMDAASAVGLCDENTIGVVAVLGSTFD
                     GSYEPVAEICAALDEVQERSGLDIPVHVDGASGAMIAPFLDPELAWDFRLPRVASINTS
                     GHKYGLVYPGVGWALWRDMEALPEELVFRVNYLGGDMPTFALNFSRPGAQVAAQYYTFL
                     RLGRAGFRAVQQATRDVARSTAERIEALGDFTLLTRGDQLPVFAFTTADHVTSYDVFDV
                     SRRMKERGWLLPAYTFPPNREDLSVLRIVCRNGFSHDLADLFLADLTQLLPELRQQTAP
                     LDRPERLATAFHH"
ORIGIN
        1 ccgcttctgg aacttctccc ggatctcggc gaccgacggc acgacgtccg gccccacccc
       61 gtccatcacg taatccgcgt gcccctccag gagggacatc acggcggtaa gccgcgccag
      121 gatctcgcgc tgggccggcg tctggacgag atcgacgagc gagcggccgc cgtcctcttc
      181 ctcctcgccc tcgggccggg cgcctgccag tgactgggcg gcctcccgca gccgctccag
      241 gagggtgccc ggatcgatgt cggtctcccc gaggaacgac tggatctcgc cctcgatgtg
      301 gtcgcgcagc cacggcacgg ccgtgaactg ggtgcggtgc gtctcctcgt gcaggcacac
      361 ccacagccgg aagtcgtgcg gttccacttc gagctcacgc tcgacgtgga cgatgttcgg
      421 ggcgaccagc agcagccggc cgccctgctc accggccggc aggtcccggc tgggcggcgc
      481 gaacgtctcg tactggccga gcacccgcga cgccaggaac gacagcagca tccccagctc
      541 cacgccggtc accttgccgc cgaccgcgcc cagcaccgcg ccaccgggga ccgtcgagcg
      601 gcggtcctcc atcttggcga gcagcggttt gagcaccgcc cggaaaccgg cgacgttcgc
      661 cctgacccag ccgggccggt ccacgaccag gacgggcgtg tcgtgcggca cctcgccctg
      721 cgcgtccggc tgcgcaagcc gcgtgaacgc ccgcacgtgc gcctcggacg ccttggcgtg
      781 cctgcgcaac tcggcgacga tcgcccgcgc ctcgtcccgg ctcacctctg ggcccggccg
      841 cacgaaccgg gtcgcggtcg cgaccgcgag attccagtcg accatctcgg ttccaccgat
      901 gctcgtcatg acttcacggt acgggcccgt gagtccacgg ggtagccgac cacgtacttg
      961 tctgcggcac cgcgggtgtt gttcaccgtt gcgcgctttg cggcgccccg cacgtagcca
     1021 cctgccccgc cgcggggcgt ctcaccgttg cgcctggcgg cgggcgtggt gttgtcgggt
     1081 gcggtgccgg ccctccagac ttcgtcctcc ggtccagccc ctcccgtgag tgggagttct
     1141 tagctggttg ggggcaggcc tgatcagtcg gctgcacgct cgcgggcatt acgtgcaccc
     1201 ccaccaccgt ttccttcccc ctcacgggag gggacgggcc ggaggggccg gttgtgtgga
     1261 cgtaaagcgt cagcagtcca cacaaccggc cccggaggcc cgtcaccgca cccgacaaca
     1321 acccagcccg ccgcaggcgc aacggcgagc aagacccgcg gcgccgcaga caggtacgtg
     1381 ggcggcgccg caaagcgcgc aacggcgagc aagccccgcg gcgggacggc caagtacgtg
     1441 ggaagtcaac gacaaccgca attcgccacc gcagaagcca agttgtccag tgcccgctgc
     1501 gcgcccggcg catccgtcgt gccggtggtc atgaaggaga agaccaggag gcggccgtcg
     1561 gcgtcgacga ccgtgccggc gagggtgttg acgccggtga gcgtgcccgt cttggcgcgg
     1621 accgcgcccg cgcccgcgct ctggcccgtg tagcggctgc tgagggtgcc ggtgaaggcc
     1681 gccaccggga ggccggtgac cacggaccgc agggccgggt ggtcgggcgc ggcggcctgc
     1741 agcaggaggc gggagagcag cgcggcggac accttgtcgc cgcggtccag gccgctgccg
     1801 tccttgaaga ccgcgccggc cagcggcagg tgctggcggg cgagggcgtc gtggacggcc
     1861 ttggcggcgc ccgcgaagct ggccggctgg ccggagccga gcgcggcctg ccgggccagc
     1921 gcctcggcga tgtcgttgtc gctgtaggtg agcatccgct ccacgaggga ggagagcggg
     1981 agggagtgga cggcggccag ccgctcggcg tgcgcgggtg ccttggcgcc cttcggggtg
     2041 ccgtcgatcg tgatgccgcg ctcgtggagg aggtcggcga aggtgcgggc ggtggtcccg
     2101 gcggggtcgg cgtcgcgggg cgccgggccg tggtcgctgt cgtcgaggcg ggcctcgtcg
     2161 gtcatcagcg ccgtgacggg ggcgaggttc tcgtcggggc cgaaggcgtg gtcgaccggc
     2221 cccgagtagg cggaggcgtc gtacccgagg cccaccgtgg tcaggtggcg ccgcttgagc
     2281 gcgcgggcgg tggcgtcggc cagcgtgcgg aggctcgcgg gctgctcggc ggtggtctgc
     2341 tgcggggcgc gggcggtgag cgtggggtcg ccgccgccga ccaggacgat gcggtccttg
     2401 ccggcggtga cgacggtggt gtcgatgcgg tgctccgggc cgcgggcgga cagcgcggcg
     2461 acggcggtgg cgagcttgac cgtggaggcc ggggtggcgg ccttgccctg gccggagccg
     2521 aagacctcgc ggccggccgc gacgtccacc acggaggcgg tgcgcagcgg gcccagcgcc
     2581 gggtccttga gcagcggcgc gagggcgtcg gcgagcccgg cgccggtcgg taccggtgcc
     2641 gcgccccggc cggcgcccgc ggcggggcga acgccgagcg cgggcaggac gggcgcggcg
     2701 ctgggcgccg ggcggtcggg ctcggcggcg tgatgctcac cactggatcc gtcgaccacc
     2761 gccgcctcgg cccgctcggc cgtacgctga ccggagtccc acgggccggc cgccgccacc
     2821 gcgacgagcg cggccgtcag gccggtggct gcggagaccg ccgtcagccg ccaggtctgc
     2881 cgggtgtgcc gcggggtgtc ctgccaggcc tgccgtacgg tgccggccgc cgcccgggcc
     2941 gagcgcccgg ccgcgtcggc cgcctcccgt gcggtgcgct gcgccgaacg ctgcgccgac
     3001 tgccatctga cctgccattt cctggtctcc ggcacctcgg accagcccct ttcgccacca
     3061 cacacctgcg tgggggacac ttaatcacca gacgtatgtg ttgatcatgg aggagccacc
     3121 cgtggagttc gacgtcacca tcgagatccc gaagggttcg cggaacaagt acgaggtgga
     3181 ccacgagacc ggtcggatcc gcctggaccg tcgactcttc acctcgacca gctacccggc
     3241 ggactacggc tttgtcgaga acaccctggg cgaggacggc gacccgctgg acgccctggt
     3301 catcctggat gagccgacct tccccggctg cctcatcaag tgccgcgcca tcggcatgtt
     3361 ccggatgacg gacgaggccg gcggcgacga caagctgctg tgcgtcccgg cgtccgaccc
     3421 gcgcgtggag cacctgcgtg acatccacca cgtgtcggag ttcgaccgcc tggagatcca
     3481 gcacttcttc gaggtctaca aggacctgga gccgggcaag tccgtcgagg gcgccaactg
     3541 ggtcggccgc gcggaggccg aggccgagat cgaggcctcg tacaagcgcg ccgaggcgca
     3601 cggcgggcac tgatcgaagc acccgggcgc aggtcggcgc ccggtgaatt tcgtacgcga
     3661 acgggcggca tccaaccggg tgccgccctt cgtccgtttg tgccgggggt ttgtgccggc
     3721 cggtgtgcgt ggcgacgcgc ggagaaattc ccgttctccg gtaaaaagcg ggaagcaatg
     3781 agtaaagttt gcgtgcggcg cccggctgct ccgtgatcat cgccaaataa gcggcagata
     3841 aattaactta cggcggcccc gcataggccc cgcctattcc gcgcaccgcg ctcccggcgg
     3901 ccaattaacc cctaagttga cagcgcgcgg cgatgctagc ttcgccacct tgacgagagc
     3961 accccaatag gcaaggcggt tctccgggtc acgcaccgcg tgaccgtcgt caaagcgggg
     4021 ggagcactca tggcacatcg cgtgggccgc gcaagccaga ggggcaggac cacacgcgcg
     4081 ggactggtcg ccacggtctt cagacagcac accgcgctgc tggtcgcggg cgtggcactg
     4141 ggcctggcgg gggtggccgc ctcgctcacc cagccggtgg ccatcggccg gctgatcgag
     4201 gcggcgggcc gcggcgaatc gctgggcgcc cccatcacct ggctcgtctc gcttttctgc
     4261 gccggcgcgc tgctcacctc tctccaggcc tacgtcatcg gccgggccgg ggagaacatc
     4321 gtcttcgacg tccgccggct cctgaccgaa cgtctgctgc gcgccgatct caccgcattc
     4381 gggaaacggc cgcagggcga tatcttcacc cgcacggtca ccgatacctc tctggtgaag
     4441 atcgcccttt cgcagagcct gacccagctg atcaccagtg gcgtcacggt gctgggcggc
     4501 gtggtgctga tgttctgcat cgacgcgggg ctgatggtca tcaccctggg ctgtctcggc
     4561 gccgccagcg tggtctccct gctgctcgcc cggaagctgc gcaaggtggc gctggagaac
     4621 cgcgacgaca tcggcgcgtt cggcaccgcc gtccagcgcg tgctctccgc cctgcccacg
     4681 gtcaaggcgt cccgcgccga gtcccgtgag gccgaccgca tcggcgcgct ggccgggaac
     4741 gcccggcggt ccggcatccg gggcaccgcc tacggcgccc tgctgacgcc gtccatgaac
     4801 gtgggcacgc agggcgcgct ggccgtcgtc gtcggggtgg gcatggcctg ggtggcccgc
     4861 ggcgagatga ccatggccgc cctgaccacg ttcatcatgt acctgttcca gctggtgtcc
     4921 ccgctggtga tgttcttcat ggcggtcggc cagttcgtcc agggccgggc cgccatccag
     4981 aaggtcgacg agctggccga catgccccag gagggcggcg ggacggcgga cgccgggcgc
     5041 gccgcgccga tggtgctggc ggcccacggc cgggcggcgg tcgagttccg cgacgtccgc
     5101 ttcggctacg agcgcgggga ccagggcgag cggtccccgg tcctgcacgg cgtctcgttc
     5161 cacgtcccgg cgcgcggact caccgccgtc gtcggaccgt ccggcgcggg caagaccacc
     5221 ctgttccagc tgatcgaacg cttctatccg gccagcggcg gcagcatcct ggtcggcggc
     5281 cggaacatcg aggcgctgcc cctcgacgcc ctgcgcgggc tggtcggtta cgtccagcag
     5341 gacagcgctg cgctgcgcgg caccgtccgg gagaacctca cctacgccag ccccgacgcc
     5401 ggcgaggacg acatccggca ggcggtggag atggccgggc tcgccaaggt cgtggccaag
     5461 ctcccgcaag gtctcgacac cgaactcggc gaccagggca gcggattgtc cggcggccag
     5521 cgccaacgcc tgtgcatcgc ccgcacgttg ctgcagaagc cggcggtcat gctgctggac
     5581 gaggccacct cccacctcga ctccgactcc gagcgggact tccgcgacgt cctgcagcgg
     5641 gtctcccggc actgcgcggt catcgccatc gcccaccgga tctccacggt gatcgacgcc
     5701 gagcagatcg tggtgctgga ggacggccgg gtccgggcca ccggccggca ccaggacctg
     5761 atgacccgcg atgcgctcta ccggcgactg gccggctccc agctgcacgc cgactccggc
     5821 ggccgcgccc ccgcccgggt cccggaccgc aaccaccccc gcgactcgga gacgacgctc
     5881 tccctctccc tggccttcgg cgggctcccg ccggccaccc tcaacgaaca gaccatccgg
     5941 ctccggccca tcaggagcga ggagcagtgg tgaacggcac cgacgtggcc gtcgtgggca
     6001 ccggccccaa cggactcgcg gccggcgtgg tcctggcccg cgccggcctg cgggtggcgc
     6061 tgtacgaacg ggccgagacc atcggcggcg ggctgcgcac cgcgcccctc ttcgacagcg
     6121 gcgtgccgca cgacctctgc tccgccgtcc accccatggc cgccgcctcc ccgttcttcc
     6181 gggcgttcgg cctggcggag cgcggtgtcg agctgctgca gcccgagatc gcctacgccc
     6241 atccgctcga cggcggccgc gcggccctgg cgtaccggtc gctggccgag acctgcgcgc
     6301 acctgggcgc cgacggcccg cgctggcggc ggctgatgga gcccctgctg gagcacagcg
     6361 acggcatcgt cgacctggtc atgaacgggc agcgccggct gcccggggac cccgcggcag
     6421 ccctgctgct ggcgagccgg gtggcggtgc acggcaccgg gctcggcgcg gcgcacttcg
     6481 ccggcgagga ggcggccgcc ctgctcaccg gtgtcgccgc ccatgcggtc ggcaagctgc
     6541 cgagcctcgc gggcggcgcg gtggccatgc tgctcggcca cctcgcgcac ggcacgggct
     6601 ggccgctgcc ccgcggcggc agcgcccgga tcgccgaggt gctggccgcg gacatcaccg
     6661 cgcacggcgg tgtcttccac accgggcacg aggtgacgga cctggaccaa ctcggcggcg
     6721 cgcgggcggt gttgctcgac accagcccca agaacttcct ggcgctcgcc ggcgaccggc
     6781 tgccccgccc gtacgcgcgc ggcctggcgc ggttccgtta cggcccgggc gccgccaagg
     6841 tcgacttcct ggtctccgag ccgatcccct ggaccgatcc cgcggtcggc cgggccgggt
     6901 cggtgcacct gggcggcacc cgcgccgaga tcgtccggca ggagacggcg accgcccgcc
     6961 ggatccggac ccgggagccc ttcgtcctgg tcgtggaccc ggcggcgacc gatccgggtc
     7021 gcgcgctgcc cgggaagcgc ccggtgtggg cgtacgcgca cgtgccgaac ggcgatccca
     7081 ccgacccgtt cgagctggtg cgggcccgca tcgagcgcta cgccccgggt ttcggggaca
     7141 ccgtcctcgc gcaccggtcc gtcgccgccg cgtcgtacga gacctacaac cccaattacg
     7201 tgggcgggga catcggcacc ggcgcgatga cgctgtacca gagcatcgcc cggcccgtgc
     7261 cgcgcctcga tccctaccgc acgccgctgc ccggcgtctt cctgtgttcc tcggccaccc
     7321 cgccggggcc cggcgtgcac ggcatgtccg gctatttcgc ggcgctctcg gcgctccggc
     7381 attgtttcgg tatacgcacc gcagccgacg tgtcactctc gccgacaccg cgtcaattca
     7441 gccctgccaa ctaatgcagg aacactcatc tgtttcggcg tcaaccaatc ccaaccggac
     7501 ctggaggcat ggagattgag ccagataatc gattgcgggc ccgctgacgt ggctgatatc
     7561 gttcgttcta aagttactcc ccccacactt cgttgagacg tcatcgcggg atcgaccaca
     7621 gctgctggtc tgaccaacca cgcagccggc cgcggttctc ccgtacggcc acccgttggt
     7681 gacgtatcgc gccttgcctc gctcttcgtc ttcttgacgt tccccgggca tcgacagtgg
     7741 gggcagaaga gaggggaaac acgggtggaa aatggagtcc aggacatagg ctacggacgc
     7801 cagttcgccg gctggtacga ccgactgctt ccggacgacg cgattaccgc cgccgccgtc
     7861 gaggggctgg cggccctcca tcccgatccc gaggggggaa ccctcgagtt cggcgtcgga
     7921 acgggacgga ttgccctccc gctctccgaa aagatcggcc acataacggg cgtggactcc
     7981 tcgccggaga tgctggacgc gctccgcgtc aagctgacgg acggcgccgg cgacgtcacc
     8041 ccggtacacg gcgacatccg cacctacacc tcggaatccc gttactccct ggtgtattgc
     8101 gtctgcgcga cgctttcggt gctcaccact cccgaggacc agcagcaggc cgtccgacgc
     8161 gcggccgacc tcctcgcccc cggcggccgg ctcgtcatcg agacgcacaa caagccgccg
     8221 gtcgtggccc tgcacgaagg cctcagccgc accacctact tcatgcccca cccggagccc
     8281 ggcagcggcg tacagaccca ctccaccctg ctcgacggtg gtctgtggca ctgctcccac
     8341 atcctctacc aggccgacgg caccacccgg gtcggttccg aactcacccg gctgaccacg
     8401 ccggaggaca tcgacggcta cgcccgcgcg gccggcctca cgcccgaatc ccatctggcg
     8461 cactgggacg gcagccccta cagcgaacgc gccccgatgt tcatctgctg ttacgtcaag
     8521 ccctgagggc agcaccgaga aaacggatga cgaaagaggg tcgcacgtgg gacgtcctcc
     8581 gatattgccg gccgacaaga aattcgctct cgtactgaga gtggtgaccg gtgaactgac
     8641 cgcagcagaa gcagctcgcg aggccggagt ctccgagcag tccgtctcga actggcgccg
     8701 gcagtttatt gagggaggcc gcaatggcct cgccggcgag agcggcaaga cctccgagaa
     8761 tgcctcccgg atagccgaac tcacccagga gatcgccaac ctgaaggcca cgataggcga
     8821 gctctacatg gaactccgca agcacagccg cggcgcgggc atccgtgttc cgctgccccg
     8881 cggcaggact cacccggcac aaagagtcaa ttaactcgtt attttatccg ggaatcgcgt
     8941 gttaggtttt tcggcaacag ccacttcgaa tcacggggga ggggaatgtg gcgtctcttg
     9001 agcgccaatt cgccgtcggc ctggccggtc tggccggcgc gagcctgctg accggcgcag
     9061 taacgcgatt caccggtggg cgcgaacgtg cgcgccgcta cctgctgcac gagaggccgg
     9121 acggcggcct cgtcgaggtc gccgtccata ttcctccgca ggcgcggcgc gtcgttctgc
     9181 tcgacaacgg cctgggcgca ccccacgaat actgggactg ggtgtgcgac gcacttcccg
     9241 acgacatggg atacgtgcgg ttcaaccgtc ccggctacgg gctcagcacg ccggtcacgc
     9301 aatacggtct gcaccggcac ttcgagctgt tgcaggaatt gcgcgacacc tacatcgccg
     9361 acctcccggt cgtcctggcg ggccattccc tgggcgggta cttcgtcgcg gcctacgcgt
     9421 cgcggcatcc gggcgcgctg aagggcgtga ccgcggtggt catgatcgac gccaccgaag
     9481 tgatcagcct gcgccactcc cgccgtacca acgtcgaccg gtgggcccgc cagtcgctgg
     9541 tgatggagca ggtctacgcc tgggccggcc tctcggcctt ccgcccggcg aagaacgtga
     9601 acaagcagta ccgcccgcag atcaaccgga gctacacggc gttcatgacg cacccgcgcg
     9661 cctgggccac cgcccgccag gagtacctgg acgccatgac gttccccgaa ctgaccgacc
     9721 tggactgccc gttgaccgtc gtcaccgcgg agaacaacgt cggggacaac gccacccacc
     9781 acgcggtcca ggccaggctc gccgccatct cgaagcggtc ccggcaccac ttcatcgacg
     9841 gctcggacca cgagtccgtg ctcgcggtgc cggcccacgc cgcacaggtg gcggaggtga
     9901 tcgccggcga accgccctcc gggaccggcc cggagcggga gaagtccgtc aaggaccgcc
     9961 cggccggcag gcgtgccgcg gaacgggaag aggagctggc gtgatcgtga aggtgaacac
    10021 cgagcgcgtg aagacggtcg ccgtcaccgc gtcgctcgcc gcctggctgg tggcgacggc
    10081 ggcggggcag ctgcccgaga accgcttcga caacctcctg cggcgcggga ggtggcagat
    10141 accggtcccg aactggcgct tcttcgggcc gaaccccgga gtcaaggaca accacctgct
    10201 ctaccgggac atcgtcgacg gcgagcccgg tgaatgggag gaagtgccca tcacccgcga
    10261 ccgcccgtgg tacgccctgg cctggaacgc ccgcaaccgc tccccgaagg ccctgttcga
    10321 cgcgagccag gacaccatcg gccgctcggt ggccttcgga ccggaactgc acctcgtcac
    10381 gctggggtcc ggctaccgcc tgctctcccg ctacatccag cgccatctgc cccatgccga
    10441 gggcgcctcg cacagccagt tcatgctgat gcagtcgttc ctcaaggccc ccggggaccg
    10501 ggagatcgag ccggtcttcg tctccctgca attcccgttg aacgaccacg ccagtgacgc
    10561 cacccctgaa gcggccgcgt ttcccgtagc ggcttagcga gccgatcaac cccctcggcc
    10621 ggaagctgcg agctcactcg gaagcccctg caccgcgtga gttcgcgccc tcccgccgaa
    10681 cggctggaga actcgctctg agatttctga gagaaagagg acagtaatgt ctgttgtggc
    10741 tgaattcgcc aacaccaacc tgatggacgt gcagccgggc cgtatcggct ccgacgccgc
    10801 gccgaccatg atgaccccgc tggccaccgt cgcgaccccc gaggccgtct ccgccggcat
    10861 cgcggtcacc tgcgccaccg ccatcgcgct caaccaggtc acgcacaacg tccagcacgg
    10921 ctgagccgac cggcagacgg tgctgcctga ccggcaccgt tagccccggt tgatcaaaga
    10981 cgcggcggca cggtacgccc gatacgcata ccgtgccgcc gcttcccatt ccaccgtact
    11041 cgcatcacat catcaggagc acccatccat gttcctcgac gctccgcccg aggtcacggc
    11101 acgccgagtg gcttcgctgg gtacgctggt ctccgcactg gaaatgctga gccagacgcg
    11161 taagttcgaa gacggtgaat tgctgagcgg ccaactggcg aatatgcgcc ccaagttcgc
    11221 caagcgattt ccccggctga cccgcgccct cagctccaag aaggcggcgg tcgccctcta
    11281 cggagtgcag gcgggtgctt ctgccgccac gctgatctgg ggccacaagc gcggggtacg
    11341 cacggcgggc agcgccgtcc tcgccgtgac gggcgcggcc ggacggctgc acaccccctt
    11401 cggtggtgac ggtgccgacc agctccagca ggtgatcaac gtcgtcctcg cctcgaccgg
    11461 caccttcaag gacggtgaga aggcccgcga cgtggccatg cgcgccatgg cactggagac
    11521 gaccatctcc tacgtcgcgt ccggcgtggt caagctcgtg tccccggtgt ggctcagcgg
    11581 cgaggcgttc agcggagtca tccgtacgca caactacggc gacccgcgca tcttccagct
    11641 cgtgcacaag tacccgatgc tgggcaagct catcacctgg ggaacggtcg ccgcggaggt
    11701 cggcttcccg ctggtcttcg tcctgccgaa gcccgcggcc aaggcctggc tcggctcgat
    11761 gaccctcttc cacctgggca tcgggcagtt catgggactc aaccgcttcg tgctggcctt
    11821 cggcgccacg cacccggcgc tcctctacgt cctcgcgcag aacgagaagc ccgcgctcgc
    11881 cgacggcgcg aagcgcgccc tggcctgcgg cgcgaagcgc gcactgccgg ccgcgagcgc
    11941 ggcctgaccg gggagacacc cccagggggt gtctcccccc gaggggcctc ttccctcggc
    12001 gggcccgccc gctagaaccc gcgggtccgc ttggccgcgc ggcggccggc gcccgcctcc
    12061 agcaacccgg gcgcccgcag gaacagccgg gcgacctcgg aaccgaggtt gacccccacc
    12121 gcgatggcca gcgccagcga ggccgcctgc accaacgacg tcagcccctg cggcagatgc
    12181 ccctgggcga agttgagcag cccgaagtac gtggcactac cgggcagcag cggaccgatc
    12241 gcggcggtca cgtacggcag cgcggacgcg taccggtacc gcgacagcaa ctgcccgaac
    12301 aggcccacca gaccggccgc gatcgcggtg gccggcaccg ggttgatccc cgcgacgttg
    12361 gcgagcgcgc cgtagaccac ccacgccacc ccgccgttca gcgtcgcgaa cgccacggtg
    12421 tgacgttcct gctggagcag cacgcagaac gccagcgcca gcagcatcga cgccagcgtc
    12481 tgcaccagcg gctcgttgta cgcccccagc gcctgctccg gattgagccg cttcaggccc
    12541 gggttcacct gcaacccgat gtacagcacg ctcagcacgc cgacgacgat gccgacgatc
    12601 agatagccga cctccagcag ccgggccgcg gcggtgatgt agtagccggt cagcccgtcg
    12661 tgcaccccgg cgaccagcgc ccgccccggg atcagcgcga acagcccacc ggtgatcacc
    12721 gcggacgcct gcacgctgga gtgcgccagc ccgaaggcca gacccaccgc cgccggcggc
    12781 atcgcggcca ccacgaactg gtagaactcc ggcagccccc gcccggacgc cagccacgcc
    12841 agccggtcac cgagcatcga gcccaccgcc gccgcgagga acaccagcga cccgccgccg
    12901 accagcatcg acgccgcacc ggacagcagc ccggaggcca ccgtcagcgc ccagctcggg
    12961 tacgggtgcc ggttacggcg gatctcggcc agcccgcggt acgcctcctc cagggtgatc
    13021 ccctcggagg cgatctcgtc gaccagccgg aacaccgcgg acaaccggtt gtagtccacc
    13081 ccgcgccgcc gcaccgtccg gctggccgtc accgggtcgt cgaccagcga cggctggtac
    13141 gagatcgaca gcagggtgaa ggtgacggtc ggctcgaccc gctccagccc gtaggcgtgc
    13201 gccacgccga acatcgccgc ctcgacgtcc tcggcgccct caccgccggc gagcaggatc
    13261 tcgccgatgc gcagggtcag gtcgaggacg cgggggacgg ccggcccggt ctcctcgtcg
    13321 ccgcgctccc ggcgctcggg gaccggccgc tccccgaccg gcatccgcag catcgtgcgc
    13381 atccggtcct gccacggcgc ctccttggtg aggcggaccg tggggatgcc gtgcggcggg
    13441 gtgaaggcca ggcccatggc ggtcgcgccc acgggcgtcg ggagcggggt ctggcccgtg
    13501 gtggtgccgg ccggcggcgt gaacgcggag ccctcctgct cggcgggcgg ctccgggcgc
    13561 agccccgccg gcagggcgaa ctccgaggtg gggtgctcgt cctcgggcag cggcgggtac
    13621 ggcacgccga gcggcggcgt gaaggcgctg tgcgcctcgt cggaggccgg cttgcgctcc
    13681 tcacccgccg cctcgtggcc cgcgccgccc ctgccgccgc gggggcctcc gtcgctgtcg
    13741 ccgctctttc cgttgctgtt gcgctggccg cgttgtgggt ccgacgccac ggtgttcgct
    13801 cctcctgtgc cgtatcgctg cgctgtgccg aatcgctgca ctgtgccgcc tacccacgat
    13861 gcttgcatgc ccgccgtgcc tgtggcgggc gggtccgcgt acgccgccgg ccgacccgcc
    13921 gtggtggttg gtcggaagcg aagcccacac acaagccccc tccggcccgt cccctcccgt
    13981 tggggggaga ggggaggccg gagggggctc gcgtcggtgg tgtggtgccg ggccggtcgg
    14041 tcagcgcttg gcgtggcggc cgcgccgggc cggttcggcg ggggacgcgc cgtgcgggcg
    14101 ggggccggcc ggggcggccg gggcttcctt cttcgccttg ccgcgggcgc gcaggaactc
    14161 gatcacgatc ggcacgaccg agatcagcac gatcgcgatc aggatcatct cgatgttctt
    14221 gtggacgaac gcgatgttgc ccagcagcga gcccatcagt gtcacccccg caccccacag
    14281 cgcgccgccg atgaggttga aggtgatgaa ggggcggtag ttcatccggc tcacgcccgc
    14341 gatgatcggc gtgaacgtcc ggacgatcgg cacgaagcgc gccaggatca gcgacttcgg
    14401 gccgtacttc tcgaagaatt catggccctt caccacgttc tcctgcttga acagcttgga
    14461 gtcgggccgt ttgaagagcg acggccccac cttgcggccg aagaggtagc cggcctggtc
    14521 accgaggacc gccgcgagca cgatcagcac acacaccacc cacagcggct gggtgatctt
    14581 gttcgtcgtg accagcaggc cggtggtgaa cagcagcgcg tcgcccggca ggaagaagcc
    14641 gatcagcagg ccggactccg cgaagacgat gaccaggacg ccgatcaggc cgaacgtcgc
    14701 gatcagatag tccgggtcca gccactgggg gccgagcgcg agagtattca cggggtgaag
    14761 gctcctgggt cgagggcgcc ggatcgtgcg ggtgcgacga gctgggacac gagcttgtgg
    14821 aacgggcgcg ggcgccgggt gtcggcccaa agctatcaac gccccgcgac ccccctcggt
    14881 tccaggcgcc cgccccggcc cccgccccgg gtcccacccg accgctcccc caccgctggc
    14941 cgtgcccccg gacccgggtg atcctggccc ctgaggaggt gcacacccat gggcatcgag
    15001 gattacggcg gcggacagca cgcacaggcc gacgtcctgg tggtgacgac gaacgacgtc
    15061 cccgggtttc acgtggaacg ggtcatcggc gaggtcttcg gcctcaccgt gcgctcccgg
    15121 cacctcggca gccagatcgg cgccgggctg aagtcgctgg tcggcggcga actgcggggc
    15181 ctgaccaaga ccctcgtgga gacccgcaac caggcgatgg agcggctgat cgagcaggcc
    15241 cgctcgcgcg gcgcgaacgc ggtgctgatg ttccgcttcg acgtcacgga ggcggccgac
    15301 gtgggcaccg aggtctgcgc ctacgggacc gccgtggtga tcgcccccat ggcctgaacc
    15361 ggcaccccgg ccggcgggcg cccggacgcg cgtcgtacgg gccgggggcg ccctgcggaa
    15421 aactgcggtc ccccggcccg tacggatcac aggtgacgga ccgcgttggc cagcatcgcg
    15481 tcccgcatgt acacggcgag cccgggccgg atcgcctcgt aggtggcggt gaaccgctcg
    15541 tcggcgacgt acatctcgcc gagcccggtg tgcgtctcgt gggagcacgc gtagtagctg
    15601 cggccgatga accgccggtg ctcctccgcg acgtccatcg ccgcctccga gtccgccggc
    15661 acgccctcgg cgagcagatc ggccatccgg cggtggatgg cgtcgaattc cgccgtcagc
    15721 cgcttccagt cctccttcgt gtacgccgcc gtccggcgct gcgtctcctt gtagccgtcg
    15781 gtgccgcccc agcgctcctc ggcctccgcg gcatacgcgt cggggtcgaa atccccgaag
    15841 acctcgaatt tctcctccgg tgtgagccgt acgttcatcc tgcgtgcctc catggcgtgt
    15901 tcgacggcct cggccatttc ctggagcttg ccgatccgcg cggtcagcag atcgtgctgg
    15961 cgccgcaggt gttcctgcgg atcggcgccc ggatcgtcca ggagggccgc gacgtcgtcg
    16021 agcgggaaac cgagctcgcg gtagaacagg atctgctgca gccggtccag gtcgtcgtcg
    16081 ccgtagcggc ggtgacctgc gtggttgcgt tcaccggggt gcagcagccc gatctcgtcg
    16141 tagtggtgca aggtgcgcac cgtcaccccg gcgaaggccg cgacctgccc taccgaatag
    16201 ctcacttccg ctcccttctc ggtacgcact ccacgatgtg tcctcacgcc gcgtgaggtg
    16261 caagtccgga ttctgaaaag cggtggggcg gcggaatcgg gggtgagatc cttccgccca
    16321 tgctggggat aacggatctg tcgacatatc tggtagggct cgcgctgatc attctgctgc
    16381 ccgggcccaa ttcgctgtac gtcgtctcgg tggcggcccg gcgcggcccc cgggtggcgt
    16441 accgggcggc cgccggcgtg ctgtgcggcg acacggtcct gatgacgctg tccgcgggcg
    16501 gcgtggcctc cctgctgcag gccagcccgg tcctcttcgg catcgtcaag ttcgccggcg
    16561 cgggctatct gacctggctc gcggtcggca tgctgcgcgg cgcctgggca ctgtggcgcg
    16621 gccgcgaggc gcggaaggcg acccgcgacg cggagacccc ggaggcggcc ggcgcggcgc
    16681 cctcggcatc cgcggcgtcc tcggcgtcct cggcgtcccg caaggaggcc gccgaacgcc
    16741 cctaccgccg cgcgctgatc gtcagcctcc tgaaccccaa ggcgatcctc ttcttcatct
    16801 ccttcttcgt gcagttcgtg gacccggcct acgcccaccc ggtgctgtcg ttcctgaccc
    16861 tgggcgcctg ggcccagctg ttcagcttca cgtacctgtc gatcctgatc ttcagcggta
    16921 cgtacctggc ggccaccttc cgccgccgcc ggcgcctgac cgcgggcctg tccgcgggcg
    16981 ccggcgcggc cttcctcggc ttcgccgcga agctgtccct ggccagcgcg agctgacccg
    17041 cttccgttgc ccgcggctac cgcgctgccg cccggtgcag cgcgtccgtg agcctgcgcg
    17101 ccgtctcggt gttgcagctc ccgagcgcga cgagcggcag cgcgtaactc cccgcgagcc
    17161 ccggcagatc gacgccgagc gacggcaacg tgatgtcgtg cgcccgcagc gcggtccgca
    17221 gcgcctcggt gcagtcgtgg acgtcctggt cgtgagggaa atggctgagc atgagctggg
    17281 cacccttctg tgcactgtgt gacgaatccc tcacagcgtg acgtcacgcc gcgtagcgtg
    17341 gaagggactg gggttgcgca cggcaacccg caaacagtgg tggtgagtta tgccccctcg
    17401 gaaagacccc gacggttcgg tgagcgtccc ctgcttctac ggcgccgagt tgcgctacaa
    17461 gcgggaggaa gccggcctga cgctggagca gttggtggaa ggcagctacc gcggcgtctc
    17521 cttcctcagc cagatcgaac gcggagagcg acggatgccg gaggacctgg cccgtcatgt
    17581 ggaccagaaa ctggggacgg acggcttctt cgagcgccgt tgtgaagatg cccggaaggc
    17641 gcgccaagtc gggcacccga gctactacgc ggacatcccc gagatggaga aagccgcagc
    17701 aacgatcgag gactgggcgc cctacgtggt ccccggcctg ctgcagaccg aaccgtacgt
    17761 ccgagaactc atccgcgccg tgaaaccgtg ggagccggcc gccgctgccg acaagacggt
    17821 acgcgcacgg ctcgcgcgag cgaggctctg gcagcaggag gaacgcccca cgtactgggc
    17881 gatcctccgc gaatcgctga tccgcaaccc gctgctcccg cctgcgcaga tggccgacca
    17941 actggagcac atcgccgagg tgatgcactc cacccagagc gttcttcaga tcctgccgga
    18001 aaccaccgtc ggccacccgc tcatgactgg cggcctggcc aagatcatga ccttcgcaga
    18061 cgcgccgccc gtggtctggg tcgaagccga cttcagcggt gaagccctcg atttcccgcc
    18121 gctcgtggcg gcataccgta agtcgtacga tcggctcagg gccgccgcac tgccacccga
    18181 ggcgtccctg gccatgatcg aggacgcggc gaggggctac agaaatgaag cgcagaagag
    18241 gaattgacct gagctcagcc acctggcgca agagcagcta cagcaacgga gacggcgccg
    18301 actgcctcga agtagccgag gacttcatcg gagcagccca ctggcggaag tccagccaca
    18361 gcaaccccga cggcgccaac tgcctcgaag tccgggacga cctccccggc ctcgtccccg
    18421 tccgggacag caaggacccg cacggaccgg cgctcgtctt cgcggccccc cactggtccg
    18481 ccttcgtcga cgccgtcaag aacggcacgc tcggcgcctg agccaccgtc gggccgacgg
    18541 taatggcccc accctcctca tgcccgtatt gtcgggcatg aggaggtatg ccgtatgcac
    18601 ctgcccgcgc acgacgtgca cgtcgccgtc atctactact cgtcgacggg caccatcgcc
    18661 acgctcgccc agtggatcgc ggacgccgcc gagcacgcgg gcgcggacgt acggctgcgg
    18721 cggaccgccg aactcgcgcc gcagaccgcc gtcgacgcca acccggcgtg ggcggccaac
    18781 gccgaggcca ccgcggacat cctggaagcc acccacgagg acatgctctg ggccgacgcg
    18841 gtgatcttcg gaacgccgac ccgcttcggg aacgtcagcg cccagctcaa ggagtacctc
    18901 gacaccctcg gcggcctctg gcaccagggc aggctggccg acaaggtcta cagcgggttc
    18961 accgcgagcg ccacccggca cgggggtcag gaatccaccc tgctggcgct ctaccagacc
    19021 gtccaccact tcggcggcat cctcgtcact cccggctaca ccgacccggc gaaataccgg
    19081 gacggcaacc cgtacggcac ctcccacgtc ggcggcccgg agaccccgct cgacgaggac
    19141 gcgcgcaccg ccgcccgtat ccaggcgcag cgcgtcgtga agttcaccaa agccatcaag
    19201 cacggcctgg cgccggcaac gtgacgcgaa ggggcgacag ttgactctgc acaaaggcgc
    19261 atcggcatcc gaccggaagc gcaccgcacg tccggtcaac cccttctacg gcgaggccga
    19321 cccggtctcc ggcatggagg agtcaccacc ccacaacatc ctccccgacg ggccggtgtc
    19381 cccgcacacc gcctaccagt tcgtccacga cgagctgatg ctggacggca acgcccggct
    19441 caacctcgcc accttcgtca cgacctggat ggaaccgcag gccggggtcc tgatggcgga
    19501 gtgccgggac aagaacatga tcgacaagga cgagtacccg cgcaccgccg aactggaacg
    19561 gcgctgcgtg gcgatgctcg ccgacctgtg gcacgcaccc gacccgtcgg ccgccgtcgg
    19621 ctgctccacc accgggtcga gcgaggccgg catgctcgcc ggcatggcgc tcaaacggcg
    19681 ctggatgcga cggaacgccg accgctaccc gagcagcgcc cgccccaacc tcgtcatggg
    19741 cgccaacgtg caggtctgct gggacaagtt ctgcaacttc tgggaggtcg agccccgcct
    19801 ggtgcccatg gagggcgacc gcttccacat ggacgccgcc tccgcggtcg gcctctgcga
    19861 cgagaacacc atcggcgtcg tcgccgtcct cggctccacc ttcgacgggt cgtacgagcc
    19921 ggtcgccgag atctgcgccg cgctcgacga ggtacaggaa cggagcggcc tggacatccc
    19981 cgtccacgtg gacggcgcgt ccggcgcgat gatcgccccg ttcctcgacc cggaactggc
    20041 ctgggacttc cgcctgccgc gggtcgcctc catcaacacc tcgggccaca aatacggcct
    20101 ggtctacccg ggcgtcggct gggcgctgtg gcgggacatg gaggccctgc cggaggagct
    20161 ggtcttccgc gtgaactacc tgggcggcga catgccgacc ttcgcgctca acttctcccg
    20221 gcccggcgcc caggtcgccg cccagtacta caccttcctc cgcctcggcc gggccggctt
    20281 ccgcgccgtc cagcaggcga cccgcgacgt ggcccgctcc actgccgaac gcatcgaggc
    20341 cctcggcgac ttcacgctcc tcacccgcgg cgaccaactg cccgtcttcg ccttcaccac
    20401 ggccgaccac gtcacctcgt acgacgtctt cgacgtctcc cgccgcatga aggaacgcgg
    20461 ctggctgctc cccgcctaca ccttcccgcc gaaccgcgag gacctctccg tcctgcggat
    20521 cgtctgccgc aacggcttct cccacgacct ggccgacctc ttcctcgccg acctgacgca
    20581 actcctcccg gaactccgcc agcagaccgc ccccctggac cgcccggaac gcctggccac
    20641 ggccttccac cactaggggg cgccggttcc accaccaggg ggcgccgttc gggtctgcgc
    20701 ggggtccgca gaggcacccg gggcccgggg gggggtgcgc agggtccgca gcggctgccg
    20761 cctcgaagtc cctcaaaggg cctcgacggc cctcacaaaa aggggcctcg acggtcctca
    20821 caaagggtcc tcggaccgcc ctcaaacgtc ctcgaaggtc tcagtgcaca tccccgggat
    20881 gaggcttccc ggtcgcgtac gggttctcct ccccctcggc gagc
//
