LOCUS       NZ_AP026073            24960 bp    DNA     linear   CON 31-DEC-2024
DEFINITION  Streptomyces nigrescens strain HEK616 chromosome.
ACCESSION   NZ_AP026073
VERSION     NZ_AP026073.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces nigrescens
  ORGANISM  Streptomyces nigrescens
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Asamizu,S. and Onaka,H.
  TITLE     Complete genome sequence of Streptomyces nigrescens HEK616
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8253039)
  AUTHORS   Asamizu,S. and Onaka,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2022) Contact:Shumpei Asamizu The University of
            Tokyo, Graduate School of Agricultural and Life Sciences; Yayoi
            1-1-1, Bunkyo, Tokyo 113-8657, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: HGAP4 v. 4.0; Falcon v. 0.3; Canu v. 0.7; Arrow
            v. 2.3.3; Pilon v. 1.22
            Genome Coverage                   :: 262x
            Sequencing Technology             :: illumina Hiseq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024349765.1-RS_2024_12_31
            Annotation Date                   :: 12/31/2024 04:23:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,326
            CDSs (total)                      :: 8,236
            Genes (coding)                    :: 8,032
            CDSs (with protein)               :: 8,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 204
            CDSs (without protein)            :: 204
            Pseudo Genes (ambiguous residues) :: 0 of 204
            Pseudo Genes (frameshifted)       :: 84 of 204
            Pseudo Genes (incomplete)         :: 166 of 204
            Pseudo Genes (internal stop)      :: 16 of 204
            Pseudo Genes (multiple problems)  :: 56 of 204
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:47:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6368055
            Orig. end                         :: 6393015
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP026073.1.
            Annotated by DFAST https://dfast.ddbj.nig.ac.jp/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24960
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="triceptide"
                     /region_number="23"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     triceptide_precursor) or triceptide_rSAM)"
                     /tool="antismash"
     cand_cluster    1..24960
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /kind="single"
                     /product="triceptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24960
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14960](-)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14960)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
     gene            89..592
                     /locus_tag="HEK616_RS28250"
                     /old_locus_tag="HEK616_57650"
     CDS             89..592
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010468602.1"
                     /locus_tag="HEK616_RS28250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57650"
                     /product="YfbM family protein"
                     /protein_id="WP_261955726.1"
                     /transl_table=11
                     /translation="MSMIGEYARVTPAELTRVLGDPEWGLALVARRREAEAAAAPEPER
                     ARCLDVDKSWDALGFLLRRAGFPVDVVHGEEAVPDAEDWGYGPPRYLTPERVRAAAEAL
                     AEIPASSLTAGVGPEDLAKAEVYPTIVWERGEPLDYVTDYYALLRPFFGAAAEKGDAML
                     MWLG"
     gene            708..1262
                     /locus_tag="HEK616_RS28255"
                     /old_locus_tag="HEK616_57660"
     CDS             708..1262
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087451.1"
                     /locus_tag="HEK616_RS28255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57660"
                     /product="hypothetical protein"
                     /protein_id="WP_261955727.1"
                     /transl_table=11
                     /translation="MLQRMSGVFIGALFGTVFVVANAHAPLSPAVGVTLRVIAVLTFAG
                     LLALALLAGRRGGAVVDADGVPRADWFRGKFGFVVAAEAVLLIGGRLALREAGAPDETS
                     VAWIALIVGLHFMALAAVWQRRSVAVPGTALTALGVAGLGMAATRAVVWVPFVSGVLSG
                     VALLAGCAYAIAQTYRSTVRP"
     gene            complement(1442..2320)
                     /locus_tag="HEK616_RS28260"
                     /old_locus_tag="HEK616_57670"
     CDS             complement(1442..2320)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087453.1"
                     /locus_tag="HEK616_RS28260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57670"
                     /product="rhomboid-like protein"
                     /protein_id="WP_261955728.1"
                     /transl_table=11
                     /translation="MSRLGTVGGMQGERASGGRAPAGSTGADGPPAPALLPGIPRQGTG
                     RDTAAPVAAAEPEPGPPRARPRPWRLLLGTPFSVGYGLLLVATSLFAEHADPTLVSQLL
                     QGSSTDVVHLAQAPLLVLVASALWIAGGLTSGYALGFLVVLPALERRIGGLRTAAVFFG
                     GHALATLATEVPVAFTVAAGGLPESSLHRLDYGISFGVMTCIGALAGVLPAWLRWPLLG
                     GAGWLAGTALLAYTDPMTDWGHLLSLTLGVASWPLLRRWRVVRTGPTPLLGDLGHPALR
                     AHPEPRGVSTP"
     misc_feature    complement(2455..2470)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     misc_feature    complement(2471..2486)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            2667..3521
                     /locus_tag="HEK616_RS28265"
                     /old_locus_tag="HEK616_57680"
     CDS             2667..3521
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536130.1"
                     /locus_tag="HEK616_RS28265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57680"
                     /product="spermidine synthase"
                     /protein_id="WP_261955729.1"
                     /transl_table=11
                     /translation="MAAPVTPPQTPSDLTESPRTLDRREGPYGEVVLRERAGSPGGPPV
                     IHEIIANGCFLMDTSDGRSERLLVDAALNELPADRQRPAVLIGGLGVGFSLARAAEQPR
                     WGRITVVEREAAVIDWHRTGPLSAISAAALADPRSEILHTDLVAHLRTPAGPHAQGAPA
                     GPHAHGAPADGASPDGTPRTDPTPDTGAGAAPVPYDALCLDIDNGPDWTVTEDNNGLYS
                     PAGLAACRDRLTPGGVLAVWSAQPSPAFEEALRNAGFQGVRTEEIPVVRGVPDVVHLAR
                     KGA"
     misc_feature    3571..3584
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.54"
                     /tool="antismash"
     gene            3595..4335
                     /locus_tag="HEK616_RS28270"
                     /old_locus_tag="HEK616_57690"
     CDS             3595..4335
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536131.1"
                     /locus_tag="HEK616_RS28270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57690"
                     /product="response regulator transcription factor"
                     /protein_id="WP_261955730.1"
                     /transl_table=11
                     /translation="MDQTQTTQGGAAAATPGAQRRVLVVEDDPTIVEAIAARLRAEGFQ
                     VQTATDGPAAVDTAEAWQPDLLVLDVMLPGFDGLEVCRRVQAQRPVPVMMLTARDDETD
                     MLVGLGVGADDYMTKPFSMRELAARVHVLLRRVERAALAAHTPRSGILRLGELEIDHAQ
                     RRVRVRGSDVHLTPTEFDLLVCLANTPRAVLSREQLLAEVWDWADASGTRTVDSHIKAL
                     RRKIGAERIRTVHGVGYALETPPA"
     gene            4332..5492
                     /locus_tag="HEK616_RS28275"
                     /old_locus_tag="HEK616_57700"
     CDS             4332..5492
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016469763.1"
                     /locus_tag="HEK616_RS28275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57700"
                     /product="ATP-binding protein"
                     /protein_id="WP_261955731.1"
                     /transl_table=11
                     /translation="MSPWRLRSWPLPKRRWWRTPVRELGKRVWDALRPLDPYRSVKAAL
                     GALVSVSVIITTLLVFVAMHSATELRVITIFSIIASLLITQFVANSLTAPLGEMTDVTR
                     AMAHGDYTRRVRADRRDEFGDLADAFNRMAADLEAVDTHRKELVANVSHELRTPIAALR
                     AVLENVVDGVCEPDPETMRTALKQTERLGRLVEHLLDLSRLDNGVVPLHARRFEVWPYL
                     SGVLKEANMSRGASTLSGLTGSGTHTRTDVHLHLDVSPPELTAYADAERLHQVVANLID
                     NAIKHSPRHGRVTVHARRGESPGGLELEVQDEGPGIPESERYRVFERFNRGGPGPSGPG
                     TDGGTGLGLAIARWAVDLHGGRIGVAESARGCRIRVTLPGQESSRS"
     gene            5743..9555
                     /locus_tag="HEK616_RS28280"
                     /old_locus_tag="HEK616_57710"
     CDS             5743..9555
                     /EC_number="4.1.1.71"
                     /GO_function="GO:0004591 - oxoglutarate dehydrogenase
                     (succinyl-transferring) activity [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980415.1"
                     /locus_tag="HEK616_RS28280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57710"
                     /product="multifunctional oxoglutarate
                     decarboxylase/oxoglutarate dehydrogenase thiamine
                     pyrophosphate-binding subunit/dihydrolipoyllysine-residue
                     succinyltransferase subunit"
                     /protein_id="WP_261955732.1"
                     /transl_table=11
                     /translation="MSLQSPNTSSISNEADQAGQGKSPAAAFGPNEWLVDEIYQQYLQD
                     PNSVDRAWWDFFADYKPGGATAPSTPAEAPAPAGAAPAQSSPAAPAADGPKPAAAPATP
                     AASAPAPTEPAPAKAAAEPAAAKPAPKPAAAKPAAAKADGEAPAAGPEFVTLRGPSAAV
                     AKNMNASLELPTATSVRAVPVKLLFDNRIVINNHLKRARGGKVSFTHLIGYAMVQALKA
                     MPSMNYSFAQKDGKPTLVKPEHVNLGLAIDLVKPNGERQLVVAAIKKAETLSFFEFWQA
                     YEDIVRRARDNKLTMDDFTGVTASLTNPGGIGTVHSVPRLMPGQSMIMGVGAMDYPAEF
                     QGTSQDALNKMGISKVMTLTSTYDHRVIQGAASGEFLRIMSQLLLGENDFYDEIFKSLR
                     IPYEPIRWMRDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYHQRKHPDLDIT
                     EHGLTLWDLEREFAVGGFSGKSMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQD
                     RVERQHKSPEREEQLRILRRLNSAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDS
                     AAESRLDEVVIGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAE
                     GTFTGLDGEQIKVSLTANPSHLEAVDPVVEGVARAKQDIINKGGTDFTVLPIQLHGDAA
                     FAGQGVVAETLNMSQLRGYRTGGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPI
                     FHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLID
                     KKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFTEVRDATTAPAAPEVPQPKA
                     EFPVFVDTAISQEVVKRIAESQVNIPEHITVHPRLLPQLQRRAAQIEDNAIDWGMGETL
                     AVGSLLMEGTAVRLAGQDSRRGTFGQRHAVLIDRETGEDYTPLLYLSEDQARFNVYDSL
                     LSEYAAMGFEYGYSLARPEALVMWEAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVTLL
                     LPHGYEGQGPDHSSARIERFLQLCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLIVF
                     TPKSMLRLKAAASKTEEFTSGGFRPVIGDSTVKPEDVRKVVFCSGKVYYDLDAERQKRG
                     ADDTAIVRIERLYPLPGKELQAEIAKFPNAEKYLWAQEEPANQGAWPFLGLNLIDHLDL
                     AVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQAQLVAEVFDA"
     misc_feature    5780..5793
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
     gene            complement(9627..10004)
                     /locus_tag="HEK616_RS28285"
                     /old_locus_tag="HEK616_57720"
     CDS             complement(9627..10004)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEK616_RS28285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEK616_57720"
                     /product="hypothetical protein"
                     /protein_id="WP_261955733.1"
                     /transl_table=11
                     /translation="MNAATDPHGPAPWPHALLDVAALRRAGARPVPFRQFVLKVRPCPA
                     RRGTWRAVGPDHPWTLGCAVNAANARSLVGQVVDAAELSGTTAQRAARTLGGTHPLSLA
                     SRTVAGPRRRSSGWDFEPQPI"
     gene            complement(10001..10210)
                     /locus_tag="HEK616_RS28290"
                     /old_locus_tag="HEK616_57730"
     CDS             complement(10001..10210)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_precursor"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041709.1"
                     /locus_tag="HEK616_RS28290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57730"
                     /product="YxD-tail cyclophane-containing RiPP peptide"
                     /protein_id="WP_261955734.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDPRGGARPAEAGPGGGALSVRNAHDLMALQQRVSHPVLADVLS
                     VLGDRVRSEPVPVAYYEDGPGLVL"
     gene            complement(10311..13316)
                     /gene="fxsT"
                     /locus_tag="HEK616_RS28295"
                     /old_locus_tag="HEK616_57740"
     CDS             complement(10311..13316)
                     /codon_start=1
                     /gene="fxsT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986809.1"
                     /locus_tag="HEK616_RS28295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57740"
                     /product="FxSxx-COOH system tetratricopeptide repeat
                     protein"
                     /protein_id="WP_261955735.1"
                     /transl_table=11
                     /translation="MADQTGSAGSADHVTISYAGFARPWAAWLSHQLEQLNYGTTLLRW
                     DPRADTALAEELSGLLEAEGRLLMVLDDWYFRLGPKTQDEWTTALREVVQPHADRFAAV
                     SVATQSLPATASLLRPADLRDLDAREANRRVLNRLGITATLPAGHEPAPGAPRFPNDPP
                     EVWNIPRRNNRFTGRDNVLEELHNKLAGSGAAGSGPPQETRIALYGISGVGKSQIAAEY
                     AHRFGNDYDVVWWISATHRGAAREQLAELASRLGLPVGQEIGDRIRAVHEALRTGRPYR
                     RWLLIFDSADDMEQIEDLVPDGRGHVLITTLTRDWSGSGSAQEIEVLPFTRVESVAYAR
                     RRAPRLTPRDADDLADAVQDLPLLLAQTAAWLDANPMPPREYIELIRRGEPSLVGIRIS
                     TDYPMAFQTSWAITLNTLRERSPAAVELLKLFAFFAPDAIPVPKLAKARRGDLPEHLAD
                     LAAEPISWNTALRRLTESTAVRLDYQNSQDSDPAVETAQMHRLYHRFLRSDMSEDERDK
                     LSATACRVLVSADPQNPFDTREWDRYAELIPHLEPAGALDSAEPAVQGLVINCVEYLRV
                     RGEYRMGLRLCEQFMFRWKNRLAPTHRTMLVLTHQHANMLRRLGRYREAEAVGSAIVDE
                     LETERGESDADLLRAKDGLAGTLMTLGAYERACALFEEVAGRYTELLGPESPRAVASRN
                     NLAIALGLLGRYEKALVLLREVVTIRERELRARHHLTLGTGTLYARMLRLTGRYRDALS
                     RQELNARLHRQVMGRHTPQTLRAEHNLALCMRRMGETAQAEALLPDVVERSKRVLGARH
                     PDTLMMMADHATFLREHGDLGRARELAEEVAERYRALVGDQHPYTLGTLGNVGLVRSEF
                     GEHAQALALAAEALAGMTAAVGPDHPWTLGCALNAAAARNRADDEEGAVELGQDIVRRA
                     AEVLGDTHPLTLSAKTALADDLRALRRARDAAKLEQEAVQQLIETLGAEHPHTVSARRR
                     RRPYWDFEPQPV"
     gene            complement(13410..14585)
                     /locus_tag="HEK616_RS28300"
                     /old_locus_tag="HEK616_57750"
     CDS             complement(13410..14585)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_rSAM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SAM_SPASM_FxsB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018853259.1"
                     /locus_tag="HEK616_RS28300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57750"
                     /product="FxsB family cyclophane-forming radical SAM/SPASM
                     peptide maturase"
                     /protein_id="WP_261955736.1"
                     /sec_met_domain="PTHR43273 (E-value: 4.5e-84, bitscore:
                     281.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="SAM_SPASM_FxsB (E-value: 9e-129, bitscore:
                     428.2, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="triceptide_rSAM (E-value: 1.0, bitscore:
                     1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRRTDRGTTAPFRQFVLKLHSRCNLACTYCYLYTGPDRSWQSRP
                     LTVRPDTVRQTAHRIAEHVSAHHLPDIRIDLHGGEPLLTGPGPLLEQAQAIRAAVPAYC
                     AVSFGVQTNGTLLTAAGLNTLADAGFLVGLSLDGGTAGLNHRRVDHAGRPSWPAAARAA
                     RLLAARPDAFAGILCTVDPATDPGQVHRSLCALSPPMLDYLLPHANWSSPPALPARPAG
                     PTPYGDWLCAVFDLWWDGPAPGPRIRLFTEIIGLLLGRPSSTEAVGLSPVVALVVDTDG
                     AIEQVDSLKSAYDGAAATGLDVFRHSFDQALAHPGLAARQQGLAGLGEQCRACPLVMVC
                     GGGNYAHRYRDAGSGFRNPSVYCADLERLIRHVASRVNAALTPNWRRADMT"
     misc_feature    complement(14662..14671)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.14"
                     /tool="antismash"
     gene            complement(14721..14960)
                     /locus_tag="HEK616_RS28305"
                     /old_locus_tag="HEK616_57760"
     CDS             complement(14721..14960)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_precursor"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986810.1"
                     /locus_tag="HEK616_RS28305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57760"
                     /product="YxD-tail cyclophane-containing RiPP peptide"
                     /protein_id="WP_261955737.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANTPRTEPAAAAPAGPSVEPLPDFTAVDVGALSELTSHPVLREV
                     AGLLLRNWLTEDEAVAYYDDGPSHVGLRRSPRND"
     gene            complement(15065..18616)
                     /locus_tag="HEK616_RS28310"
                     /old_locus_tag="HEK616_57770"
     CDS             complement(15065..18616)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603150.1"
                     /locus_tag="HEK616_RS28310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57770"
                     /product="SAV_2336 N-terminal domain-related protein"
                     /protein_id="WP_261955738.1"
                     /transl_table=11
                     /translation="MPLGEPGPGPLDELVARLTAAGLPPDARGMADALWLAQWITPDPS
                     RADGTDGGGGTGRADGADGAGEAGADGRPDRADPATFRVGPPALPGLTGGTGASSDGDG
                     SPDPAADGAASAAALREAARRRVAELLPARHEHSADPDHHRLGEVAVPIASAFPGLLPL
                     QRALRPVQRYRPPAAPVRRKLDERATAELSAHAEMVIPVLRGVHRRTAGLRLLMDGSSS
                     MAVWEQMLHDLRQVCERVGAFRDVTVHYLHPHGADVGVAATPGPGRPLRPADQLHDPTG
                     HHLTLVVSDCAGPLWRDGRMQRLLYRWAADAPLAVVQPLPQRMWGRTLLPAVAGTLVRR
                     QGPYQALDFRPARRRRRPAPPPGTETEPPRERAVPVLAATPSALGSWARLAAADAGLSL
                     RGAASVVRADHGAEPRSGPPPAPGSGEPSRMVREFDQQASPAARLLAVHLSAVPLALPV
                     IQLVQRAMLPQTGPAELAEVLLSGLVVQVPPEEFPPGERIPGGGPPEERLAATGPWYDF
                     VPGVRDALLARLSAGEAALVLKHCSLYIERTFGRSARNFPAVAVAMLSGSGREPETGQR
                     AVPEPFARVSERVLRRFEPALRPPDRRPYASDGPAADGAALLERYEQDRAVRDLIAAVR
                     LLRAAAERLPPAGTDLARALLHAWAEWRQPDALEEAERAVRAAERALGAASPADTAEGD
                     GSRDGIGGDDAGAAERTRVLIVLGRVAHARARERRAAGDPAGERTALAEAARRLDAACG
                     LMSLLDPRVLESMVLRTEVLRTEVLRRLAALPETAVPEPAATPPAAGRTGPDGTPASPL
                     PPDPLDEAERSLTTLLDRWPSGEQVPGEVYAARGGVLLDQARRAAAGRPEAPGAARPAE
                     ALAVRAADDLDTATVLLRRRGGDADRLVCETLLDLAAARRLGDGAGPPSVLSTLERARA
                     LARSLGDPVLEADSLRRIAAAQRAVHTRTGALAALDAAIDALAAALRLTAPDTPAHSSL
                     LAERGAALLLRARQEPAEEPGRRLADEAVHVLREALARVAPQDPDLGSHRLLFGRALRL
                     RHERRPSVADLHEADWILELAARGAGVPDVVCAEAWIEVGDVQLLLDRRFGSRERHDRA
                     AACYRRAAAAAGRAGSALLAARAHHRRGEVLEVTAGPRSALQAYRESWEHWQRTAADPG
                     PEAQRTRARMRALEPPA"
     misc_feature    complement(18350..18352)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18622..19683)
                     /locus_tag="HEK616_RS28315"
                     /old_locus_tag="HEK616_57780"
     CDS             complement(18622..19683)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603151.1"
                     /locus_tag="HEK616_RS28315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57780"
                     /product="AAA family ATPase"
                     /protein_id="WP_261955739.1"
                     /transl_table=11
                     /translation="MSDWLIYRGAGAPHDGIEHLPPPPPWRDFDGGPLVAPPAALDPAS
                     ERRLGVQYREASHHRPGETERELVNAALYLRRPLLVTGAPGSGKSTLAHSVAYELGLGR
                     VLSWPVVSRSTLRDGLYDYDAIGRLQDLQIARAAPSPAADGAAGGAGEDGTGEPGGGIG
                     RYIRLGPLGTALLPAARPRVLLVDELDKSDIDLPNDLLNVLEEGEFRIPELERLAGSAP
                     EVEVLTDDGARVTVRGGRVRCHAFPFIVLTSNGERDFPAPLLRRCIHLHIPAPDKERLA
                     AMVRAHFGEGAAERYASVIDRFLDREPGDVRAVDQLFNAIHLTQKAGWTDQDEEETRRR
                     LTAELMRPLDRTR"
     misc_feature    19843..19856
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.13"
                     /tool="antismash"
     gene            complement(20007..22187)
                     /locus_tag="HEK616_RS28320"
                     /old_locus_tag="HEK616_57790"
     CDS             complement(20007..22187)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986913.1"
                     /locus_tag="HEK616_RS28320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57790"
                     /product="serine protease"
                     /protein_id="WP_261955740.1"
                     /transl_table=11
                     /translation="MATAEQRTGDRARYAQLLEHAGRTTVALRAAPGAADVRLWGSGVL
                     IAPGWVLTCAHVLAASDGRRRETGPDGVFGVAFGGRVEPARLVYDLSRPAPEAGPGAAR
                     ADLALVRLLDPGADHPCAWLSDQPATLLEDAYIFRGHDRSGGADVPDVPGGHDRPDGDE
                     RPAAGKRVLRESAVRGPAGAPGPSAAVDPFIAVRFGARDARGLQFGSDVRVSPGASGGP
                     LIDCDRGEVVGIVKGRHQQDHVGLAVPVTALRGLGPEHLVAGAEGLGPEPYHALMGLHD
                     RWHWTGQDLARAGGPTWFDAQHAVMAGRGRLWGVQERLQALDLLARLPAPRDPLLVEAA
                     VDEALERGERPGAWSLRTWRDGHGALYQGSDPYTELRAFVHYLRIVAQRTADEVRDVPG
                     EEAAAVREGTARLAEFVQAKAVVLQPQDRRRIGPVRRRPRSVLVEFEPLFYDENGHELY
                     NWSVSEGYGRGQWLRVDVQESAGGVPFEEAREQVLRGLGGRLLRADGDAGPGARVRLEV
                     AVPEGRWHTAAGRWEVAASTRRTARRRPVGPGRAVVLRDQGRREEVDPAWLRRWQGMTA
                     ASALTALRIPPTGAGARPGGSAETIWRLLETAEDGALPALCRTVADGFGRDAVGVALDT
                     GFPAGLWPARGHGEERECDAGCEEFHRGVRELLQGSGGLVRLPELVRQLRAKAAEAAEE
                     GSHWARDLILLYDDPEDPLPPLFPDRPQVSPG"
     gene            complement(22187..22648)
                     /locus_tag="HEK616_RS28325"
                     /old_locus_tag="HEK616_57800"
     CDS             complement(22187..22648)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087463.1"
                     /locus_tag="HEK616_RS28325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57800"
                     /product="CU044_2847 family protein"
                     /protein_id="WP_261955741.1"
                     /transl_table=11
                     /translation="MQDRAQRIELPDGTEVWARVSRLDAPGLDGTDALHGDEDGDFEDV
                     GAWDALGARVEGLREVIGGVAASVRQATARVAPHETSVTFGVELSAKPGKAIALLADGE
                     AKTNLSVTLTWRQDRQDGRDRQDHDGGAPAGAPPAEPPAGRREPDDAGR"
     gene            22801..22980
                     /locus_tag="HEK616_RS28330"
                     /old_locus_tag="HEK616_57810"
     CDS             22801..22980
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889383.1"
                     /locus_tag="HEK616_RS28330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57810"
                     /product="DUF6104 family protein"
                     /protein_id="WP_030415955.1"
                     /transl_table=11
                     /translation="MYFTDRGIEELENRRGEEEVTLAWVADQLRTFVDLNPDFEVPVER
                     LATWLARLDDEDDE"
     misc_feature    complement(23217..23230)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.35"
                     /tool="antismash"
     gene            23244..24119
                     /locus_tag="HEK616_RS28335"
                     /old_locus_tag="HEK616_57820"
     CDS             23244..24119
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536136.1"
                     /locus_tag="HEK616_RS28335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_57820"
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_261955742.1"
                     /transl_table=11
                     /translation="MSARTAWSQNPIEVTAPRTLEIPDSVRGLNVRLVGGTVNVVGTSD
                     GSPPRLEISELHGPPLSVSFDNGTLSVAYEDLPWKGFMKFLDRKGWQRSAVVSVAVPAG
                     TRVEVGVIGASAVVSGISGRTDVRGISGGITLVGLTGGVRADTVSGDVEVQSLQGDLRF
                     NSVSGDLTVIDGAGEAVRADSVSGDMVLDLDPGKGADITLTTVSGEVAIRLPDPADARV
                     DANTTTGTVSNAFDDLRVSGQWGAKRITGSLGAGTGRLKVTTISGGLALLRRPAYEDSP
                     ADPPAEKKVL"
ORIGIN
        1 gggccgccat tctcccaggc cgcgctgtgg gctctgccgg gcggcgaggc cgggggcgtt
       61 gtcagtggtc gcccgtagcc tcggtcacat gagcatgatc ggagagtacg cacgtgtgac
      121 acctgccgaa ctcacccgtg tcctcggcga tcccgagtgg gggctggcgc tcgtcgcccg
      181 gcggcgcgag gcggaggccg cggcggcccc ggagccggag cgggcgcgct gcctggacgt
      241 cgacaagagc tgggacgcgc tgggattcct gctgcgccgc gcgggcttcc cggtggacgt
      301 cgtgcacggc gaggaagccg tcccggacgc cgaggactgg ggctacggcc cgccgcgcta
      361 cctcaccccc gagcgggtgc gggccgcggc cgaggcgctc gcggagatac ccgcgtcgag
      421 cctgacggcc ggcgtcggcc cggaggacct ggccaaggcg gaggtctacc cgacgatcgt
      481 gtgggagcgg ggggaaccac tggactacgt caccgattac tacgcactcc tgcggccgtt
      541 cttcggcgcg gcggcggaga agggggacgc gatgctcatg tggctggggt aggcgggcag
      601 ttcgccgccg cgacggccgg gccggccgcg accgggcaag ccgcaacggc ccctcaccgt
      661 cggcccggac gctcctcacg gcacgtcagg actgctaggt tcgcggcatg ttgcagcgga
      721 tgtccggggt gttcatcggt gcactgttcg ggacggtctt cgtggtcgcc aacgcgcacg
      781 ctccactgag ccccgccgtc ggcgtcaccc tgcgcgtgat cgcggtgctc accttcgcgg
      841 gcctgctggc gctggcgctg ctggcgggcc gccggggcgg ggccgtggtg gacgcggacg
      901 gggttccccg ggcggactgg ttccgcggga agttcgggtt cgtggtggcg gccgaggcgg
      961 tactgctgat cggcggccgg ctcgcgctgc gcgaggcggg cgccccggac gagacctccg
     1021 tcgcctggat cgcgctcatc gtcgggctgc acttcatggc gctggccgcg gtctggcagc
     1081 ggcgctcggt cgccgttccg ggcacggcgc tcaccgcgct cggcgtggcc ggtctcggta
     1141 tggccgcgac ccgtgcggtg gtgtgggtgc cgttcgtcag cggcgtcctg tccggtgtcg
     1201 ccctgctggc cggctgcgcc tacgccatcg cgcagaccta ccggtccacc gtacggccgt
     1261 agttggccca cggcgggcgg ggcccgtgcg gtaggcgcac ggcgcgtcgg tgcgtagtcg
     1321 cgccccggca ggcggcgtat ctccctcggc gcgggcgcgc actccctgta gtgcagtgcg
     1381 ggcgcgggcg ccgcggctca gggtgtgatc cccgcgatgg ggggtgtcca cgcgccgccc
     1441 ttcagggggt ggacacaccc cgcggttcag gatgcgcccg cagggccggg tggcccaggt
     1501 cgccgaggag cggggtgggg ccggtgcgaa cgacccgcca gcggcggagc agtggccagc
     1561 tcgccacgcc cagcgtgagc gagagcagat ggccccagtc cgtcatcggg tcggtgtagg
     1621 cgagcagggc ggtgccggcg agccagccgg cgccgcccag cagcggccag cgcagccagg
     1681 ccggcagtac cccggccagc gcgccgatgc aggtcatcac gccgaagctg atgccgtagt
     1741 cgaggcggtg cagcgagctc tccggcagcc cgccggcggc gacggtgaag gcgaccggca
     1801 cctccgtggc gagggtggcc agcgcatgcc cgccgaagaa gaccgcggcg gtgcgcagcc
     1861 cgccgatccg ccgctccagc gcgggcagta cgaccaggaa tccgagggcg taaccggagg
     1921 tcagtccgcc ggcgatccag agcgcgctgg cgaccagcac cagcagcggg gcctgcgcga
     1981 ggtgcaccac gtccgtgctg gagccctgga gcagctggga gaccagggtc gggtccgcat
     2041 gctcggcgaa gagtgaggtg gccacgagca gcaggccgta gccgacggaa aagggggtgc
     2101 cgagcagcag ccgccagggc cgcgggcggg cgcgcggcgg accgggctcc ggctccgccg
     2161 cggccacggg tgccgcggtg tcccggccgg tgccctgccg tgggatgccc ggcaggaggg
     2221 cgggggcggg tggtccgtcc gctccggtgc tcccggccgg tgcccggccg cccgacgccc
     2281 gctccccctg cattcccccg acggttccca gcctgctcac ggtccgaggc cccttccgtc
     2341 ctgacgcatc caccgagcca cgcccggggt acctgggccg cgcgtgagtg ctccgccgtg
     2401 cacaacgtcc gctcgccctg cacaacgtcg cggaccagcc tgcacgctca acccatgaag
     2461 aagctgtgag agtgagatgc ctcacacgaa gcaaccgtca cgggacgctc ccggtcccgc
     2521 tcgggcctcg ctccacccgc ccgcgccacc gttcccgggg ccgccccacg taccgccgcc
     2581 ccggtccgcc cgcacgccgc cgccccgccc cacgactccc cgtaagccgt tggaccacca
     2641 cgccccctct tggccaccat ggccgtatgg ctgctcccgt taccccgccg cagaccccgt
     2701 ccgacctcac cgagtcgccg cgcacgctcg accgccggga gggcccgtac ggcgaggtgg
     2761 tcctgcggga acgggccggg tccccgggcg gcccgcccgt catccacgag atcatcgcca
     2821 acggctgctt cctgatggac acctccgacg gccgctccga gcgcctgctg gtcgacgccg
     2881 cgctgaacga gctgccggcc gaccggcagc ggcccgccgt cctcatcggc ggcctgggcg
     2941 tcggcttctc gctggcccgg gcggccgagc agccgcgctg gggccggatc acggtcgtcg
     3001 aacgcgaggc cgcggtcatc gactggcacc ggaccggccc gctgtccgcg atctcggccg
     3061 cggcgctggc cgacccgcgc agcgagatcc tgcacaccga cctcgtcgcg cacctccgca
     3121 cgcccgccgg cccgcacgcc cagggggcgc ccgccggtcc gcacgcccac ggggcgcccg
     3181 ccgacggagc gagccccgac gggacgcccc ggaccgaccc gacccccgac accggcgccg
     3241 gcgccgctcc cgtcccctac gacgccctct gcctcgacat cgacaacggc cccgactgga
     3301 ccgtcaccga ggacaacaac ggcctctact cccccgccgg cctcgccgcc tgccgggacc
     3361 ggctcacccc gggcggggtg ctcgccgtct ggtccgcgca gccctccccg gcgttcgagg
     3421 aagcgctgcg aaatgccggt ttccaggggg tgcgtacgga agagatcccg gttgtccgag
     3481 gagtccccga cgtggtccac ctcgctcgga agggtgcgta gccgacagtc acaccatgcc
     3541 cgtacgctgc tgcccagcaa gacgcgacca cgcagggaca tgcaggggcg ggcgatggac
     3601 cagactcaga caacgcaggg cggcgccgcc gctgccacgc cgggcgccca gcgccgggta
     3661 ctggtggtgg aggacgaccc cacgatcgtc gaagccatcg cggccaggct gcgcgccgag
     3721 ggcttccagg tgcagacggc caccgacggc ccggccgcgg tggacaccgc cgaggcctgg
     3781 cagcccgacc tgctggtcct ggacgtgatg ctgccgggct tcgacggcct ggaggtctgc
     3841 cgccgggtcc aggcccagcg ccccgttccg gtgatgatgc tcaccgcccg ggacgacgag
     3901 acggacatgc tggtcggcct cggcgtcggc gccgacgact acatgaccaa gccgttctcc
     3961 atgcgcgagc tggccgcccg ggtgcacgtc ctgctccgcc gggtcgagcg cgccgcgctg
     4021 gccgcgcaca ccccgcgcag cggcatcctc cgactgggtg agctggagat cgaccacgcc
     4081 cagcgccggg tccgggtccg cgggtccgac gtccatctga ccccgaccga gttcgacctg
     4141 ctggtctgcc tggcgaacac cccgcgcgcg gtgctctccc gcgagcagct gctggccgag
     4201 gtgtgggact gggcggacgc ctccgggacc cgtacggtcg acagccacat caaggcgctc
     4261 cgccgcaaga tcggcgccga gcggatccgt acggtccacg gcgtcggcta cgccctggag
     4321 accccgccgg catgagcccc tggcgcctgc gttcctggcc gctgccgaaa cgccggtggt
     4381 ggcggacacc cgtccgtgag ctgggaaaac gggtctggga cgcactgcgc ccgctggacc
     4441 cgtaccgctc cgtcaaggcc gcgctcggcg cactggtcag cgtctcggtg atcatcacca
     4501 ccctgctggt gttcgtcgcg atgcactcgg cgaccgagct gcgggtgatc acgatcttct
     4561 cgatcatcgc ctcgctgctg atcacccagt tcgtggcgaa cagcctgacc gccccgctcg
     4621 gcgagatgac ggacgtcacc cgcgcgatgg cgcacggtga ctacacccgc cgggtgcgcg
     4681 cggaccgccg cgacgagttc ggcgacctgg ccgacgcctt caaccggatg gcggccgacc
     4741 tcgaagcggt ggacacccac cgcaaggagc tggtcgccaa tgtctcgcac gagctgcgca
     4801 cgccgatcgc cgcgctgcgc gccgtgctgg agaacgtcgt cgacggcgtc tgcgagcccg
     4861 accccgagac gatgcggacc gccctgaagc agaccgagcg gctgggccgc ctggtcgagc
     4921 acctcctcga cctgtcgcgg ctggacaacg gcgtggtgcc gctgcacgcc cggcgcttcg
     4981 aggtctggcc gtatctgtcc ggggtgctca aggaggccaa catgagccgc ggcgcctcca
     5041 ccctctccgg gctgaccggc tccggcaccc acacccgtac ggacgtccat ctgcacctcg
     5101 acgtctcgcc gcccgagctg accgcgtacg cggacgcgga gcggctgcac caggtcgtgg
     5161 cgaatctcat cgacaacgcg atcaagcaca gcccccggca cggccgggtc accgtgcatg
     5221 cccggcgcgg cgagagcccg gggggcctgg agctggaggt gcaggacgag ggccccggca
     5281 tcccggagtc ggagcgctac cgggtcttcg agcgcttcaa ccgcggcggc ccgggcccct
     5341 cggggccggg gacggacggc ggtacgggcc tgggcctggc gatcgcccgc tgggcggtgg
     5401 acctgcacgg cggccggatc ggtgtggccg aatcggcacg gggttgccgg atccgggtca
     5461 ctcttccggg gcaggagtca tcacggagct gacgaccgta cggacggtcg ctggcgtagg
     5521 gtcggtggta ggagcactca ccccgtgggt gcgacggcgg tgagtgctac ccgcacgcgg
     5581 gcaaacttcg tgtgtttccc gccaagtcat gccctgaaac ccttcggtga atgtgacgtg
     5641 cgcgacgagt ggccctcccg gactgcacca aaggtcacaa gaggcgtagc ctttattccc
     5701 gctgtccacc accttaggaa gcggaagagg gcggttgccg ccgtgtcgct acagtccccc
     5761 aacacttcga gcatctcgaa cgaggccgat caagcggggc agggcaagag ccctgctgct
     5821 gccttcggcc ccaatgagtg gctcgtcgac gagatctacc agcagtacct ccaggacccg
     5881 aactcggtag accgagcctg gtgggacttc ttcgccgact acaagccggg cggcgccacc
     5941 gcgccgagca cgccggcgga ggcccccgcc cccgccgggg ccgccccggc ccagtcgtcc
     6001 cccgcggccc cggccgcgga cgggccgaag cccgccgccg cgccggccac cccggccgcg
     6061 agcgccccgg cccccaccga gcccgcgccg gccaaggccg ccgccgagcc cgccgccgcg
     6121 aagcccgcgc cgaagccggc cgccgcgaag ccggccgccg cgaaggccga cggcgaggcc
     6181 ccggccgccg gtcccgagtt cgtcaccctg cgcggcccgt cggccgccgt tgcgaagaac
     6241 atgaacgcct ccctggagct gccgacggcc acgtccgtcc gcgcggtccc ggtgaagctg
     6301 ctcttcgaca accgcatcgt catcaacaac cacctcaagc gcgcccgggg cgggaaggtc
     6361 tccttcaccc acctcatcgg gtacgcgatg gtgcaggccc tcaaggccat gccgtcgatg
     6421 aactactcct tcgcgcagaa ggacggcaag ccgaccctgg tcaagcccga gcacgtcaac
     6481 ctcggcctgg ccatcgacct ggtgaagccg aacggcgagc gccagctggt cgtcgccgcg
     6541 atcaagaagg ccgagacgct ctcgttcttc gagttctggc aggcctacga ggacatcgtc
     6601 cgccgggccc gggacaacaa gctgacgatg gacgacttca ccggagtcac cgcgtcgctg
     6661 accaaccccg gcggcatcgg cacggtccac tccgtgccgc gcctgatgcc cggccagtcg
     6721 atgatcatgg gcgtcggcgc gatggactac cccgccgagt tccagggcac ctcgcaggac
     6781 gccctgaaca agatgggcat ctccaaggtc atgacgctga ccagcaccta tgaccaccgc
     6841 gtgatccagg gcgccgcctc cggcgagttc ctgcgcatca tgagccagct gctgctcggc
     6901 gagaacgact tctacgacga gatcttcaag tcgctgcgga tcccctacga gccgatccgc
     6961 tggatgcgcg acatcgacgc gtcgcacgac gacgacgtca ccaaggccgc ccgggtcttc
     7021 gagctgatcc actcctaccg ggtccgcggc cacgtcatgg ccgacaccga cccgctggag
     7081 taccaccagc gcaagcaccc cgacctggac atcaccgagc acggcctcac cctgtgggac
     7141 ctggagcggg agttcgcggt cggcggcttc tccggcaagt ccatgatgaa gctgcgcgac
     7201 atcctgggcg tgctgcgcga ctcgtactgc cgcaccaccg gcatcgagtt catgcacatc
     7261 caggacccca agcagcgcaa gtggatccag gaccgggtcg agcgtcagca caagtcgccc
     7321 gagcgcgagg agcagctgcg catcctgcgc cggctgaact ccgccgaggc gttcgagacg
     7381 ttcctgcaga ccaagtacgt cggccagaag cgcttctcgc tggagggcgg cgagtccgtc
     7441 atcccgctgc tggacgcggt catcgactcc gcggccgagt cgcggctgga cgaggtcgtc
     7501 atcggcatgg cccaccgcgg ccgcctcaac gtcctcgcca acatcgtcgg caagtcctac
     7561 gcgcagatct tccgcgagtt cgagggcaac ctcgacccga agtcgatgca cggctccggc
     7621 gacgtgaagt accacctggg cgccgagggc accttcaccg gtctggacgg cgagcagatc
     7681 aaggtctcgc tgaccgccaa cccctcccac ctggaggccg tggacccggt cgtcgagggt
     7741 gtcgcgcgcg ccaagcagga catcatcaac aagggcggca cggacttcac cgtcctgccg
     7801 atccagctgc acggtgacgc cgcgttcgcc ggccagggcg tggtcgccga gacgctgaac
     7861 atgtcgcagc tgcgcggcta ccgcaccggc ggcacggtgc acgtcgtcat caacaaccag
     7921 gtcggcttca ccgccgcccc ggagtcgtcg cgctcctcca tgtacgccac cgacgtggcc
     7981 cgcatgatcg aggcgccgat cttccacgtg aacggtgacg accccgaggc cgtcgtccgc
     8041 gtcgcccgtc tggccttcga gttccgccag gcgttcaaca aggacgtggt catcgacctc
     8101 atctgctacc gccgccgcgg ccacaacgag tcggacaacc cggccttcac ccagccgctg
     8161 atgtacgacc tgatcgacaa gaagcgctcg gtgcgcaagc tctacaccga gtcgctgatc
     8221 ggccgtggtg acatcaccct cgaagaggcg gagcaggcgc tccaggactt ccagggacag
     8281 ctggagaagg tcttcaccga ggtccgcgac gccacgacgg ctccggccgc ccccgaggtg
     8341 ccgcagccca aggcggagtt cccggtcttc gtcgacaccg cgatctccca ggaggtcgtc
     8401 aagcggatcg ccgagtcgca ggtcaacatc cccgagcaca tcaccgtgca cccgcgtctg
     8461 ctgccccagc tgcagcgccg cgcggcccag atcgaggaca acgccatcga ctggggcatg
     8521 ggcgagaccc tcgccgtcgg ttcgctgctg atggagggca ccgcggtccg gctcgccggc
     8581 caggactccc gccgcggtac gttcggccag cggcacgcgg tgctcatcga ccgcgagacc
     8641 ggcgaggact acaccccgct gctctacctc tccgaggacc aggcccgctt caacgtctac
     8701 gactcgctgc tgagcgagta cgcggcgatg ggcttcgagt acggctactc gctggcccgc
     8761 cccgaggcgc tggtcatgtg ggaggcccag ttcggtgact tcgtcaacgg cgcgcagacc
     8821 gtcgtcgacg agttcatctc ctcggccgag cagaagtggg gccagacctc cggcgtcacc
     8881 ctcctcctgc cgcacggcta cgagggccag ggcccggacc actcctcggc ccggatcgag
     8941 cggttcctgc agctctgcgc gcagaacaac atgaccgtgg cgatgccgac gctgccctcc
     9001 aactacttcc acctgctgcg ctggcaggtg cacaacccgc accacaagcc gctcatcgtc
     9061 ttcaccccga agtcgatgct gcgtctgaag gccgcggcgt cgaagacgga ggagttcacc
     9121 tcgggcggct tccgcccggt gatcggcgac tccacggtca agcccgagga cgtccgcaag
     9181 gtcgtcttct gctccggcaa ggtctactac gacctggacg ccgagcggca gaagcggggc
     9241 gcggacgaca ccgcgatcgt ccgcatcgag cggctctacc cgctgcccgg caaggagctc
     9301 caggcggaga tcgccaagtt cccgaacgcc gagaagtacc tgtgggcgca ggaagagccg
     9361 gcgaaccagg gtgcctggcc gttcctcggc ctcaacctga tcgaccacct cgacctggcg
     9421 gtcggtgccg acgtcccgca cggcgagcgg ctgcggcgca tctcgcgccc gcactcctcg
     9481 tccccggccg tcggctccgc caagcgccac caggccgagc aggcccagct ggtcgcggag
     9541 gtcttcgacg cgtaggcgtc accggaccga caggcaggaa cggaagggcc cgtcccctcg
     9601 ggggcgggcc cttccgcctg ctccggtcag atgggctgcg gctcgaagtc ccagccggag
     9661 gatcggcgac gggggcctgc gaccgtcctg gaggcgaggc tcaggggatg ggtgccgccc
     9721 aacgtccgcg ccgcccgctg cgcggtcgtg ccactcagct cggccgcgtc caccacctgc
     9781 ccgacgaggc tccgggcgtt cgccgcgttc accgcgcagc ccagtgtcca gggatggtcg
     9841 gggcccacgg cacgccacgt tcctctcctg gcgggacagg gccgcacctt gaggacgaac
     9901 tgccggaacg gcaccggccg cgcccccgcc cggcgcaggg cggccacgtc cagaagggcg
     9961 tgcggccagg gcgccgggcc gtgcgggtcg gtcgcggcgt tcacagcacc aggcccgggc
    10021 cgtcctcgta gtacgcgacg ggaacgggct cgctacggac ccggtcgccg aggacgctca
    10081 gcacatccgc cagcaccgga tgcgacaccc gctgttgcag ggccatcaga tcgtgcgcgt
    10141 tcctgacgga cagcgcgcct cccccaggac cggcctccgc cggccgggcg ccgcctcgag
    10201 gatccgacac aatgctccct ccagtgaggc cgacacggag tgtcccttcc gctgcgacgc
    10261 tcgtcggcgc tcatcgcccg gtgaggagcc cccatcgtag tacgcacccc ctagaccggt
    10321 tggggctcga agtcccagta cggccggcgc cggcgccggg ccgagacggt gtgggggtgt
    10381 tcggcgccca gggtctcgat gagctgctgg acggcttcct gctccagttt cgcggcgtcc
    10441 ctggcgcggc gcagggcccg caggtcgtcg gcgagcgcgg tcttggcgga cagggtcagc
    10501 ggatgggtgt cgccgagcac ttccgcggcc cgccgcacga tgtcctggcc gagctcgacg
    10561 gcgccttcct cgtcgtcggc gcggttgcgg gccgcggccg cgttcagggc gcatcccagg
    10621 gtccaggggt ggtcggggcc caccgccgcg gtcatcccgg cgagcgcttc cgccgcgagg
    10681 gccagggcct gggcgtgctc gccgaattcc gaccggacga gcccgacgtt gcccagcgtg
    10741 cccagggtgt acgggtgctg gtccccgacc agggcgcggt agcgctcggc cacctcctcg
    10801 gccagctccc gggcccgtcc gaggtcgccg tgttcgcgca ggaacgtggc gtggtcggcc
    10861 atcatcatga gggtgtccgg gtgccgggcg cccagcaccc gcttgctgcg ttcgaccacg
    10921 tccggcagca gtgcctcggc ctgcgcggtc tcgcccatac ggcgcatgca cagggcgagg
    10981 ttgtgctcgg cccggagggt ctgcggggtg tggcgtccca tgacctggcg gtgcagccgg
    11041 gcgttcagct cctggcggga gagggcgtcg cggtaccgtc cggtcagccg cagcatccgg
    11101 gcgtagaggg tgccggtgcc gagcgtgagg tggtggcggg cgcgcagctc gcgctcgcgg
    11161 atcgtgacca cctcgcggag caggaccagc gccttctcgt agcgcccgag caggcccagg
    11221 gcgatggcga ggttgttgcg ggaggcgacc gcacgcggtg attcggggcc gagcaactcg
    11281 gtgtaccggc cggcgacctc ctcgaagagg gcgcaggccc gctcgtacgc gccgagggtc
    11341 atgagcgtgc cggccaggcc gtccttggcc cgcagcagat cggcatcgga ctcgccgcgt
    11401 tcggtctcca gctcgtccac gatcgcgctg ccgaccgcct cggcctcgcg gtaccggccc
    11461 agccggcgca gcatgttggc gtgctggtgg gtcaggacga gcatggtgcg atgggtgggc
    11521 gcgagccggt tcttccagcg gaacatgaac tgttcgcaca gccggaggcc catgcggtac
    11581 tcgccgcgca cccggaggta ttcgacgcag ttgatgacca ggccctggac cgcgggttcg
    11641 gcgctgtcca gcgcgccggc cggctccagg tgcgggatga gctcggcgta gcggtcccac
    11701 tcgcgggtgt cgaacgggtt ctggggatcg gccgagacca gcacccggca ggccgtcgcg
    11761 gacagcttgt cgcgttcgtc ctcggacatg tcactgcgca ggaagcggtg gtagagccgg
    11821 tgcatctgcg cggtttcgac ggccgggtcg gagtcctggg agttctggta gtcgaggcgt
    11881 accgcggtgg actcggtcag ccggcgcagc gcggtgttcc agctgatcgg ttcggcggcg
    11941 agatcggcca ggtgctcggg caggtcaccg cggcgggcct tggccagctt gggcaccggg
    12001 atggcgtccg gcgcgaagaa ggcgaacagt ttgaggagtt cgaccgcggc cgggctgcgt
    12061 tcccggaggg tgttgagggt tatggcccaa ctggtctgga aggccatcgg gtagtcggtg
    12121 gagatgcgga tcccgacgag actgggctcg ccccgccgga tcagttcgat gtactcccgg
    12181 ggcggcatcg ggttggcgtc cagccaggcc gcggtctgcg ccagcagcag gggcaggtcc
    12241 tgcaccgcgt ccgccaggtc gtcggcgtcc ctgggcgtca gccgcggggc gcggcgccgg
    12301 gcgtaggcga cgctctcgac ccgggtgaag ggcagcacct cgatctcctg ggcgctgccg
    12361 gagccggacc agtcacgggt gagcgtggtg atcaggacgt ggccccggcc gtccgggacg
    12421 aggtcctcga tctgctccat gtcgtcggcg ctgtcgaaga tcagcagcca gcggcggtag
    12481 gggcgtccgg tgcgcagcgc ctcgtgcacc gccctgatcc ggtcgccgat ctcctggccg
    12541 accggcaggc cgagccggga ggccagctcg gcgagctgct cgcgcgccgc gccgcggtgg
    12601 gtggcgctga tccaccacac cacgtcgtag tcgttgccga accggtgcgc gtactcggcc
    12661 gcgatctggc tcttgccgac gccggagatg ccgtacagcg cgatccgggt ctcctgcggc
    12721 gggccggaac cggcggctcc ggagccggcc agcttgttgt ggagttcttc gaggacgttg
    12781 tcccggccgg tgaagcggtt gttgcggcgg ggaatgttcc agacctcggg cgggtcgttc
    12841 gggaagcgcg gtgctccggg ggccggctcg tgccccgccg ggagcgtggc ggtgatgccg
    12901 agccggttca gtacccggcg gttggcctcg cgggcgtcga ggtcccggag gtcggcgggc
    12961 cgcagcaggg aggccgtggc gggcaggctc tgggtcgcga cgctcaccgc cgcgaaccgg
    13021 tcggcgtgcg gctgcaccac ctcgcgcagg gcggtggtcc attcgtcctg ggtcttgggg
    13081 cccagccgga agtaccagtc gtccagcacc atcaggagcc ggccctcggc ctccagcaga
    13141 ccggacagtt cctcggccag cgcggtgtcc gcccgagggt cccagcgcag cagggtcgtg
    13201 ccgtagttca gctgctccag ctggtgcgag agccaggcgg cccagggcct ggcgaagccc
    13261 gcataactga tcgtgacgtg gtctgcggag ccggcggaac cggtctgatc ggccatgcga
    13321 ccgtctcccc tgcgataagc ggtgcgtcaa agcatgcgcg agctggctgg cacgataacc
    13381 caagtgtgca ccgattcgtc gactgtgcgt caggtcatgt cggcacgccg ccagttgggc
    13441 gtcagcgcgg cgttcacccg gcttgcgacg tggcggatca gccgctccag gtcggcgcag
    13501 tagacggacg ggttgcggaa gccgctgccg gcgtcgcggt agcggtgggc gtagttgccg
    13561 cccccgcaga ccatcaccag cgggcaggcc cggcactgct caccgaggcc ggccaggccc
    13621 tgttgccggg ccgccaggcc ggggtgggcg agggcctggt cgaagctgtg ccggaagacg
    13681 tccagaccgg tggcggcggc accgtcgtag gcggacttga gcgagtccac ctgctcgatg
    13741 gcgccgtcgg tgtccaccac cagggcgacc acgggcgaca gtccgaccgc ctcggtggag
    13801 ctgggcctcc ccaggagcag cccgatgatc tcggtgaaca gccgtatccg gggcccgggc
    13861 gccggcccgt cccaccacag gtcgaacacc gcgcagagcc agtcgccgta cggtgtgggg
    13921 cccgcgggcc gggccggaag ggccggcggg ctggaccagt tggcgtgcgg cagcaggtag
    13981 tcgagcatcg gcggggacag ggcgcaaagg ctccggtgga cctgcccggg gtcggtggcg
    14041 gggtcgacgg tgcagaggat gccggcgaac gcgtcgggcc gggcggccag cagtcgggcc
    14101 gcgcgggcgg ccgcgggcca ggagggccgg cccgcgtggt cgacccggcg gtggttcagt
    14161 ccggcggtgc cgccgtccag gctgagcccg accaggaacc ccgcgtcggc cagggtgttc
    14221 aggccggcgg cggtgaggag ggtcccgttg gtctggacgc cgaagctcac cgcgcagtac
    14281 gcgggcaccg ccgcgcggat ggcctgcgcc tgttccagga gcgggcccgg tccggtgagc
    14341 agcggctccc cgccgtgcag atcgatacgg atgtcgggga ggtggtgggc gctgacgtgt
    14401 tcggcgatcc ggtgggcggt ctggcgcacg gtgtccggcc gtacggtcag cggccggctc
    14461 tgccagctgc ggtccggacc ggtgtagagg tagcagtacg tgcacgccag attgcaccgg
    14521 ctgtgcagct tgagcacgaa ttgccggaag ggggccgtgg tgccccggtc ggttctgcgc
    14581 agcacgacgc cgcccccctg cctgggccga ggttccctgg acacccgtcg acgcccgctg
    14641 ctccatgtct ggctcagccc ggaaaaaagc aatcaattcc gatcgataac tggccgaatt
    14701 ctttaaccta ttgcccagaa tcaatcgttg cggggagagc gccgcagacc cacatgggaa
    14761 gggccgtcgt cgtaataggc caccgcctcg tcctccgtca gccagttgcg gagcagcagg
    14821 cccgccactt cccggagcac cggatgggac gtcagctcgg acaacgcacc cacatcgacc
    14881 gccgtgaaat ccggcagcgg ctcgaccgac ggcccggccg gggcggccgc agccggttcg
    14941 gtgcgggggg tgttcgccac gctgctctcc tctggccggc tggacggggg tgttcccgga
    15001 ctccggtcca cggaaacacg tgcgggcggc ggcggccgga cggccggccg ggggtgccgg
    15061 gggctcaggc ggggggttcg agggcgcgca tacgggcgcg ggtgcgctgc gcctcggggc
    15121 ccgggtcggc ggcggtgcgc tgccagtgtt cccagctctc gcggtaggcc tggagcgcgg
    15181 agcgggggcc ggcggtgact tcgaggacct cgccccggcg gtggtgggcg cgggcggcca
    15241 gcagggcgct gccggcccgg ccggcggccg cggcggcgcg gcggtagcag gcggcggcgc
    15301 ggtcgtggcg ctcgcgggag ccgaaccggc ggtccagcag cagttgcacg tccccgacct
    15361 cgatccacgc ctcggcacac accacgtccg gcaccccggc gccccgggcg gccagttcca
    15421 ggatccagtc ggcctcgtgc agatcggcga ccgagggccg gcgctcgtgg cgcagccgca
    15481 gcgcccggcc gaacagcagc cggtgactgc cgagatcggg gtcctgcggc gcgaccctgg
    15541 ccagcgcctc gcgcaggacg tgcaccgcct cgtcggccag ccgccggccg ggctcctcgg
    15601 ccggctcctg gcgggcccgc agcagcagcg cggcaccgcg ttcggcgagc agcgagctgt
    15661 gcgcgggggt gtccggtgcg gtcagccgga gcgcggcggc gagcgcgtcg atcgccgcgt
    15721 ccagggccgc gagcgcgccg gtacgggtat gaacggcgcg ctgggccgcg gcgatccggc
    15781 gcaggctgtc ggcctccagc accgggtcgc cgagggaccg cgcgagcgcc cgggcccgct
    15841 ccagggtgga gagcacggac ggcggccccg cgccgtcgcc cagccggcgg gccgccgcga
    15901 ggtccagcag cgtctcgcac accagacggt cggcgtcgcc gccgcggcgg cgcagcagga
    15961 cggtggcggt gtcgaggtcg tcggcggcgc gcaccgcgag cgcctcggcg ggacgggccg
    16021 cgccgggcgc ctcgggccgg ccggcggcgg cccggcgggc ctggtcgagc agcaccccgc
    16081 cgcgggcggc gtagacctcg ccggggacct gctccccgct gggccagcgg tcgaggaggg
    16141 tggtgaggga gcgctccgcc tcgtcgagcg gatccggggg gagcggtgat gccggggtcc
    16201 cgtccggacc ggtgcggccg gccgccggcg gggtcgcggc gggctccggg acggccgtct
    16261 ccggcagggc ggccaggcgg cgcaggacct cggtgcgcag gacctcggtg cgcagcacca
    16321 tgctctccag gacccggggg tcgagcaggc tcatcagccc gcaggcggcg tccagtcggc
    16381 gggcggcctc ggcgagcgcg gtgcgctccc cggccgggtc accggcggcg cggcgctccc
    16441 gggcgcgggc gtgggcgacc cggccgagca cgatcagcac ccgggtccgc tcggccgcgc
    16501 cggcgtcgtc gcccccgatg ccgtcccggg agccgtcacc ttccgcggtg tccgcggggg
    16561 acgccgcccc cagggcgcgt tccgccgcgc gcaccgcccg ctccgcctcc tccagggcgt
    16621 ccggctgccg ccattccgcc caggcgtgca gcagcgcccg ggcgaggtcc gtgccggccg
    16681 gcgggaggcg ttccgcggcg gcccgcagca gccggaccgc cgcgatcaga tcgcggacgg
    16741 cgcggtcctg ttcgtagcgc tccaggaggg cggcgccgtc cgccgccggt ccgtcggagg
    16801 cgtacggccg ccggtcgggc gggcgcagcg ccggttcgaa gcggcgcagg acgcgttcgg
    16861 agacccgggc gaacggttcg ggcaccgccc gctgtccggt ctccggctcc cggccgctgc
    16921 cggacagcat ggccacggcg accgcgggaa aattgcgcgc gctgcggccg aaggtgcgct
    16981 cgatgtagag cgagcagtgc ttgagcacca gcgcggcctc gcccgcgctg agccgggcga
    17041 gcagtgcgtc ccgtacgccg ggcacgaagt cgtaccaggg gccggtcgcc gcgagccgct
    17101 cctccggggg gccgccgccc gggatgcgct cccccggcgg gaactcctcc ggcggcacct
    17161 gcacgaccag cccgctcagc agcacctcgg ccagctcggc cggcccggtc tggggcagca
    17221 tcgcgcgctg gacgagctgg atgacgggca gcgcgagcgg cacggcggag aggtgcaccg
    17281 cgagcagccg ggcggccggc gacgcctgct ggtcgaactc ccggaccatc cgggagggtt
    17341 cgccgctccc gggcgcgggc ggcgggccgg agcgcggttc ggcgccgtgg tcggcgcgga
    17401 cgacggaggc cgcgccgcgc agcgagagac cggcgtccgc ggcggccagc cgggcccagg
    17461 agcccagcgc ggacggggtg gcggcgagca ccgggacggc ccgctcgcgc ggcggctcgg
    17521 tctccgtgcc cggtggcggg gcgggccggc gacgacgccg ggcgggccgg aagtcgaggg
    17581 cctggtacgg gccctggcgc cggaccaggg tgccggcgac ggcgggcagc agcgtccgtc
    17641 cccacatccg ctgcggcagc ggctggacga cggcgagcgg ggcgtcggcc gcccagcggt
    17701 acagcagccg ctgcatccgg ccgtcgcgcc agagggggcc ggcgcagtcg ctgacgacga
    17761 gggtgaggtg gtggcccgtc gggtcgtgca gctggtcggc ggggcgcagc ggacggccgg
    17821 ggccgggggt cgcggcgacg ccgacgtccg cgccgtgcgg atggaggtag tggaccgtga
    17881 cgtcccggaa ggcgcccacc cgctcgcaga cctggcgcag gtcgtgcagc atctgctccc
    17941 atacggccat cgaggacgag ccgtccatca gcagccggag cccggccgtg cggcggtgca
    18001 ccccgcgcag caccgggatg accatctcgg cgtgcgcgga gagttcggcg gtggcccgct
    18061 cgtccagctt gcggcggacc ggggcggccg gcgggcggta ccgctggacc ggccgcaggg
    18121 cacgctgcag cggcaggagt ccggggaacg cggaggcgat cgggaccgcg acctcgccga
    18181 ggcggtggtg gtccgggtcg gcgctgtgct cgtgccgggc gggcagcagc tccgcgacgc
    18241 ggcgccgggc ggcctcccgg agggcggcgg cggacgcggc cccgtcggcg gccgggtccg
    18301 gggagccgtc gccgtcggac gacgctcccg tcccgcccgt cagacccggt aacgcgggag
    18361 gacccacccg gaaagtggcc ggatccgcac ggtcgggacg gccgtcggca ccggcctctc
    18421 cggccccgtc agcaccgtcg gcccgacccg tcccgccgcc cccgtccgtc ccgtcggcac
    18481 gggacggatc cggggtgatc cactgggcga gccagagggc gtcggccatc ccgcgggcat
    18541 cgggcggcag ccccgccgcg gtcagccggg cgacgagctc gtcgagggga cctggaccgg
    18601 gctccccgag gggcaccgca ctcacctcgt ccgatcgagc ggccgcatca actccgccgt
    18661 cagccgccgc cgggtctcct cctcgtcctg gtccgtccag ccggccttct gggtgaggtg
    18721 gatggcgttg aagagctggt cgacggcgcg cacgtcaccg ggctcgcggt ccaggaagcg
    18781 gtcgatcacg gatgcgtagc gctcggccgc gccctcgccg aagtgggccc gcaccatggc
    18841 ggccagccgc tccttgtcgg gcgccgggat gtggaggtgg atgcagcggc gcagcagggg
    18901 cgccgggaag tcgcgctccc cgttgctggt gaggacgatg aaggggaagg cgtggcagcg
    18961 cacccggccg ccgcggaccg tcacccgcgc gccgtcgtcg gtgagcacct ccacctcggg
    19021 cgcggatccg gccagccgct ccagctccgg aatccggaac tccccttcct ccaggacgtt
    19081 gaggaggtcg ttgggcaggt cgatgtcgct cttgtcgagc tcgtcgacga gcagcacccg
    19141 gggccgggcg gccggcaaca gggccgtgcc cagcgggccg aggcggatgt agcggccgat
    19201 cccgccgccc ggttcgccgg tgccgtcctc gccggcccct ccggcggcgc cgtccgcggc
    19261 gggcgacggg gcggcgcggg cgatctggag gtcctggagc cggccgatgg cgtcgtagtc
    19321 gtacaggccg tcgcggagcg tgctgcggct gaccaccggc cagctgagca cccggccgag
    19381 gccgagttcg tacgcgaccg aatgcgcgag ggtgctcttg ccgctgcccg gggcgccggt
    19441 caccagcagc ggccggcgca ggtagagcgc ggcgttgacc agctcgcgct cggtctcgcc
    19501 ggggcggtgg tggctggcct cgcggtactg cacgccgagc ctgcgctcgg aggcggggtc
    19561 gagcgcggcc ggcggcgcca cgagggggcc gccgtcgaaa tcacgccaag ggggtggcgg
    19621 cggaaggtgc tcaattccgt cgtgcggtgc tcccgcgcca cggtagatga gccagtcgct
    19681 cacgtcggaa ctcctcgtcg ccggaccggg tcggtacctt cggtcacgtc atcacgccac
    19741 cacgcggcgc gcctcacgtc gtcccgctca catcgtcacg cgcacgcacc ccggccacgc
    19801 cgaactgccg cccgctgtcg cgtcgttgcg ccacatcgtc cacgaacaag tcttccacga
    19861 agctatgaca gtacccatcc ctacggaagc gcacggggcg gtttccggtc tcgcgggtcg
    19921 cgggcggggc gctgcgggcc gggcgggggc acggaaccgg ggcacggcat cggccacccg
    19981 gcgcacgcgg tcgtgcgctc ccccgctcac cccggggaca cctggggccg gtccgggaag
    20041 agcgggggca gcgggtcctc cgggtcgtcg tagaggagga tcaggtcccg ggcccagtga
    20101 ctgccctcct ctgccgcctc ggcggccttg gcgcgcagct gccggacgag ctcggggagc
    20161 cggaccagac cgcccgagcc ctggagcaac tcccgtacgc cgcggtggaa ttcctcgcag
    20221 ccggcgtcgc actcccgctc ctcgccgtgg ccgcgggccg gccacagccc ggccgggaag
    20281 ccggtgtcca gggccacccc gaccgcgtcc cggccgaacc cgtcggcgac cgtccggcac
    20341 agcgcgggca gcgccccgtc ctccgccgtc tccagcagcc gccagatcgt ttcggcggag
    20401 ccgccggggc gcgcgccggc acccgtgggc ggaatccgca acgccgtcag cgccgaggcg
    20461 gcggtcatgc cctgccagcg gcgcagccag gccggatcga cctcctcgcg ccggccctgg
    20521 tcccgcagga ccacggcacg gccgggaccc accggccgcc gccgggcggt gcgccgggtc
    20581 gacgcggcga cctcccacct gccggcggcg gtgtgccagc gcccttcggg gacggcgacc
    20641 tccaggcgca cccgggcgcc cggcccggcg tccccgtcgg cccgcagcag ccggccgccg
    20701 agcccgcgca gcacctgctc gcgcgcctcc tcgaacggca ccccgccggc cgactcctgg
    20761 acgtccaccc gcagccactg cccccggccg tagccctcac tgaccgacca gttgtagagc
    20821 tcatggccgt tctcgtcgta gaagagcggc tcgaactcga cgaggacgga gcgcgggcgg
    20881 cggcgcaccg ggccgatccg gcggcggtcc tgcggctgca ggacgaccgc cttggcctgg
    20941 acgaactccg cgagcctggc ggtcccttcg cggaccgcgg cggcctcctc gcccggtacg
    21001 tcccgcacct cgtcggcggt ccgctgggcc acgatccgca ggtagtgcac gaaggcgcgg
    21061 agctccgtgt acgggtcgct gccctgatag agcgcgccgt gcccgtcccg ccaggtgcgc
    21121 agcgaccagg cgccgggccg ttcaccgcgc tccagcgcct cgtcgaccgc cgcctcgacg
    21181 agcagcgggt cgcgcggtgc gggcaaccgg gcgagcaggt ccagggcctg cagccgctcc
    21241 tggacgcccc agaggcggcc gcggcccgcc atgacggcgt gctgggcgtc gaaccaggtg
    21301 ggcccgccgg cccgggcgag gtcctgcccg gtccagtgcc agcggtcgtg cagccccatc
    21361 agcgcgtggt acggctcggg cccgagccct tcggcgccgg ccaccagatg ctccgggccc
    21421 agcccgcgca gcgcggtgac cggcaccgcg aggccgacgt ggtcctgctg gtggcggccc
    21481 ttgacgatgc cgacgacctc gccgcggtca cagtcgatca gcggcccgcc ggacgccccg
    21541 gggctgaccc ggacatcgct gccgaactgg agcccccggg cgtcccgggc gccgaagcgg
    21601 acggcgatga acgggtccac ggcggcggac gggcccggcg ccccggccgg cccgcgcacc
    21661 gccgactcac gtagtacgcg tttcccggcg gcgggccgct cgtccccgtc cggccggtcg
    21721 tggcccccgg gcacgtccgg aacgtccgcc ccgcccgacc ggtcgtggcc gcggaagatg
    21781 taggcgtcct ccaggagcgt cgccggctgg tcgctcagcc aggcgcacgg atggtcggcc
    21841 cccgggtcga gcagccgcac cagggcgaga tcggcgcggg ccgcgccggg gccggcctcc
    21901 ggggcgggcc ggctcaggtc gtacaccagg cgcgcgggct ccacccggcc gccgaacgcg
    21961 accccgaaga ccccgtccgg accggtctcg cggcgccgtc cgtcgctcgc cgcgaggacg
    22021 tgtgcgcagg tcagcaccca tccgggggcg atcagcaccc cactgcccca cagccggacg
    22081 tcggctgcgc ccggcgccgc gcgcagggcg acggtggtgc ggccggcgtg ctccaggagc
    22141 tgggcgtacc gggcgcggtc accggtgcgt tgctcggcgg tcgccatcag cggcccgcgt
    22201 catcgggctc ccggcggccg gccggaggct ccgccggcgg tgcgcccgcc ggcgcgcccc
    22261 cgtcgtggtc ctgccggtcg cggccgtcct ggcggtcctg ccgccaggtg agggtgacgg
    22321 agaggttggt cttggcctcc ccgtcggcga gcagggcgat cgccttgccc ggtttcgcgg
    22381 acagttccac gccgaaggtc acgctggtct cgtgcggcgc gacccgtgcg gtggcctggc
    22441 ggacgctggc ggcgaccccg ccgatcacct cgcggagccc ctcgacccgg gcgcccagcg
    22501 cgtcccaggc gccgacgtcc tcgaagtccc cgtcctcgtc cccgtgcagg gcgtccgtcc
    22561 cgtcgagccc gggggcgtcc agccgggaga cccgggccca gacctccgtc ccgtcgggca
    22621 gttcgatgcg ctgtgcgcga tcttgcatca cggcctccgc tccccctgga cggcaattcc
    22681 ccgattgccg caggaccgct gacaggtgat caggctagcc cccgggcggc tggggcgcga
    22741 gaggtccgtg ggcctgccta tcctggccgg gaatgaccca tgacccctgg tggagagcgc
    22801 gtgtatttca ctgaccgtgg catcgaggag ctggagaacc ggcgcggcga ggaggaggtc
    22861 accctcgcgt gggtggccga tcagctgcgc acgttcgtcg acctgaaccc ggacttcgag
    22921 gttccggtgg agcggctggc cacctggctg gcgcggctgg acgacgagga cgacgagtag
    22981 cggacgagcg ggaggagcgg cgaggagcag cggggcgggg gcgccgtacg gcacgggccc
    23041 gaccgtcagg accgtacggc gcgaggacgc cgtggggacg gcggccaggg ttcgatgacc
    23101 agggacgaag accagggatg acgtaggggg cgaatagggg acgggtcagg gtcggggccg
    23161 cttgacttcc cgaagccgcg atatatcgtg tctgttgagg acgcgatatg ttgcgttgca
    23221 cggctatcca ggggaggcca ggaatgtcag cccggaccgc gtggtcgcag aacccgatcg
    23281 aggtgaccgc cccgcgcacg ctggagatcc cggactccgt ccgcgggctc aacgtccgcc
    23341 tggtgggcgg cacggtcaac gtcgtcggca cctccgacgg cagccccccg cgcctggaga
    23401 tcagcgaact gcacggcccg cccctgtccg tctccttcga caacggcacc ctctccgtcg
    23461 cgtacgagga cctgccctgg aaggggttca tgaagttcct cgaccgcaag gggtggcagc
    23521 gcagcgcggt ggtctcggtg gcggtgccgg ccggcacccg ggtcgaggtc ggggtgatcg
    23581 gcgccagcgc ggtggtctcc gggatctcgg ggcgcacgga cgtccgcggc atctccggcg
    23641 gcatcacgct ggtcggcctg accggcgggg tgcgggccga cacggtctcc ggcgacgtcg
    23701 aggtgcagtc gctccagggg gacctgcggt tcaactccgt ctcgggcgat ctgacggtga
    23761 tcgacggcgc gggcgaggcg gtgcgcgcgg actccgtcag cggcgacatg gtcctggacc
    23821 tcgaccccgg caagggcgcc gacatcaccc tcaccacggt ctccggcgag gtcgccatcc
    23881 ggctgcccga cccggccgac gccagggtcg atgccaacac cacgaccggc acggtctcca
    23941 acgccttcga cgacctccgg gtcagcggcc agtggggcgc aaagaggatc accggctcgc
    24001 tgggcgcagg caccggccgc ctcaaggtca ccacgatctc cggcggactg gccctgctgc
    24061 gccgccccgc ctacgaggac tcccccgccg acccgcccgc cgagaagaag gtgctctgag
    24121 catgcccccc gtcttcgccc atggccgcct gcgcctgtat ctcctcaagc tgctggacga
    24181 ggccccgcgg cacggctacg agatcatccg cctcctggag gagcgcttcc agggcctcta
    24241 cgccccctcc gccggcacgg tctacccgcg gctggccaag ctggaggccg agggcctggt
    24301 gacgcacgcg accgagggcg gccgcaaggt ctattcgatc accgacgccg gacgggccga
    24361 actcgccgac cgcggcggcg agctggccga tctggaaatg gagataaggg agtcggtcgc
    24421 cgcgctggcc tccgacatcc gcgaggacgt gaacggctcg gcgcgcgacc tgcgccgcga
    24481 gatgcgcgag gccgcccagc aggcccgcgc gggcgcgtcc gcggggggcg ggcgcggcgg
    24541 cgcgaagaac ggcgccccgg ggggcgccgg acggccgttc cccgaggccg cggactactt
    24601 cgacggcgcg ttcggcgaca aggaggcctg gcggcaggcg aaggaggagt tccggcgcgc
    24661 caaggaggag tggaaggaac aggcccggcg ggccaaggag gagagcaagc gggcccggca
    24721 ggacgcccag cgcgcccgta agcaggcccg ggaggcgcag gtcttcgcgc gcgaggagat
    24781 ccagcgggtc atcaagcgcg tccaggacca ggcccagggc gcggtgcgga cgggcgactg
    24841 gtcgggcgcg gtccgggagg cgctctccga ggtgtcccgc gaggtcggcc ggttcaccgg
    24901 cgaacggccc gcggcggacc gccccgccgg accgaccgcc cccgccgacg gcgccgaggt
//
