LOCUS       NZ_AP026073            41482 bp    DNA     linear   CON 31-DEC-2024
DEFINITION  Streptomyces nigrescens strain HEK616 chromosome.
ACCESSION   NZ_AP026073
VERSION     NZ_AP026073.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces nigrescens
  ORGANISM  Streptomyces nigrescens
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Asamizu,S. and Onaka,H.
  TITLE     Complete genome sequence of Streptomyces nigrescens HEK616
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8253039)
  AUTHORS   Asamizu,S. and Onaka,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2022) Contact:Shumpei Asamizu The University of
            Tokyo, Graduate School of Agricultural and Life Sciences; Yayoi
            1-1-1, Bunkyo, Tokyo 113-8657, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: HGAP4 v. 4.0; Falcon v. 0.3; Canu v. 0.7; Arrow
            v. 2.3.3; Pilon v. 1.22
            Genome Coverage                   :: 262x
            Sequencing Technology             :: illumina Hiseq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024349765.1-RS_2024_12_31
            Annotation Date                   :: 12/31/2024 04:23:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,326
            CDSs (total)                      :: 8,236
            Genes (coding)                    :: 8,032
            CDSs (with protein)               :: 8,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 204
            CDSs (without protein)            :: 204
            Pseudo Genes (ambiguous residues) :: 0 of 204
            Pseudo Genes (frameshifted)       :: 84 of 204
            Pseudo Genes (incomplete)         :: 166 of 204
            Pseudo Genes (internal stop)      :: 16 of 204
            Pseudo Genes (multiple problems)  :: 56 of 204
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:47:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4148859
            Orig. end                         :: 4190341
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP026073.1.
            Annotated by DFAST https://dfast.ddbj.nig.ac.jp/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..41482
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="other"
                     /region_number="14"
                     /rules="(Neocarzinostat or bcpB or frbD or mitE or prnB or
                     CaiA or bacilysin or orf2_PTase)"
                     /tool="antismash"
     cand_cluster    1..41482
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Neocarzinostat or bcpB or frbD or mitE
                     or prnB or CaiA or bacilysin or orf2_PTase)"
                     /kind="single"
                     /product="other"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41482
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[20000:21482](+)"
                     /cutoff="20000"
                     /detection_rule="(Neocarzinostat or bcpB or frbD or mitE or
                     prnB or CaiA or bacilysin or orf2_PTase)"
                     /neighbourhood="20000"
                     /product="other"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21482
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Neocarzinostat or bcpB or frbD or mitE or
                     prnB or CaiA or bacilysin or orf2_PTase)"
                     /neighbourhood="20000"
                     /product="other"
                     /protocluster_number="1"
     gene            792..1769
                     /locus_tag="HEK616_RS18455"
                     /old_locus_tag="HEK616_37660"
     CDS             792..1769
                     /EC_number="3.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007451617.1"
                     /locus_tag="HEK616_RS18455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37660"
                     /product="alpha/beta hydrolase family esterase"
                     /protein_id="WP_261954031.1"
                     /transl_table=11
                     /translation="MDAFPTLRRGRPVRAWSLALALLLGPALAGCGATGQPASPTKAAG
                     SPSAKADATHRQVRVDGRTREYLLHRPTAPGGRTRPLVIAFHGRGSTASYLREQSRLDE
                     DARARGMLIAYPEGLGKLWGAGTRATERRPDPDLDVRFTKALIAELVRTERADPKRVYV
                     VGFSNGGSMALRVAAQSPGLLAGAAAVSGELPTGDAAVKPTGPVPLMIIYGAADRVRPL
                     AGMPHPSPAPAGEEPVTPTMSARDSAAAFATAGGATAAAKTKAEAGYDRTVWRLKAPGA
                     TVQLLVMHDAGHTWPGSRIKPPAGFGPTSTALNATSTILDFFHL"
     gene            1828..3474
                     /locus_tag="HEK616_RS18460"
                     /old_locus_tag="HEK616_37670"
     CDS             1828..3474
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324823.1"
                     /locus_tag="HEK616_RS18460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37670"
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="WP_261954032.1"
                     /transl_table=11
                     /translation="MPRSRYPAPATTRRRTPRPVVRTVTSVAVVSAVVAGGSYAAGLGP
                     FARGATEPEPAALAQAHGFLADWAAGRLPAAAGRTTSPTTAQHVLRNFTAGLDIRRPTL
                     TVAAPPIRAEDDTVDVPFTATMPIADLGTWTYRSKLPLRQQGDGSWKVDWSLSVVHPRL
                     SGAKRFHLEREAPVATPDVTDRKGASLSGARFPSLNPVLNQLDPGTGGGAPRGAIQLVD
                     RATGKVERTEATFGKKPVRSARRPVRTTLDATWQAAAERALASGAHGRNASLVALRIDN
                     GEILAMANSPSSGFNRAVSGTYAPGSTWKIVTSSALLLKGAVAPSDVVDCPKYLTVGKE
                     FHNVETSEHRNATFLKDFTESCNTAFISLRGKLGNREPGDVAGRYFGVGQKWHVGIASY
                     DGSVPAPRDETEKAASMIGQGRVQANPLIMASVIATAVSGTFHQPSITHRNQDPTTTTP
                     LPRKVVTQLRAMLRTTVTDGTARILSGLPGEVGAKTGTAEVSDDEPNNGWLAAHRGNVA
                     LACVVEQGVTGGGSAGPVIRDLLTAVPTDPS"
     gene            complement(3490..4416)
                     /locus_tag="HEK616_RS18465"
                     /old_locus_tag="HEK616_37680"
     CDS             complement(3490..4416)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492049.1"
                     /locus_tag="HEK616_RS18465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37680"
                     /product="STM4015 family protein"
                     /protein_id="WP_261954033.1"
                     /transl_table=11
                     /translation="MYGHQRTRQFHGRPVVEFDPDRAVRTDPQGTAWRLDAAISGPPEF
                     PEVFERFVQTVDTTQVTTLILGFTGFDGPAAATHLLDAAERFPRLEALFLGDEPDFFCI
                     YQTDLTPVLERFPLLERLDVRGKQGWELSPFRHAALKTLRCESCCLPSDVMRAVAASDL
                     PGLERLDLWLGVDDGTGEVADVCDLAPVLSGERLPALRSLGLQNSALQDEIAEEVAEAA
                     VVPRLRSLSLALGTLTDRGAEALLNGQPLDHLERLDLHHHYLSDPMMERLRVAHPTTDV
                     DLGDAQGEFHGPFDDEAYNMVADGRDF"
     misc_feature    4428..4443
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.35"
                     /tool="antismash"
     gene            complement(4429..5076)
                     /locus_tag="HEK616_RS18470"
                     /old_locus_tag="HEK616_37690"
     CDS             complement(4429..5076)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014177446.1"
                     /locus_tag="HEK616_RS18470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37690"
                     /product="response regulator transcription factor"
                     /protein_id="WP_261954034.1"
                     /transl_table=11
                     /translation="MRIVVAEDLYLLRDGMVRLIEAYGHQVVATASTGPETLDALVSWR
                     PDVAVVDVRMPPTQSDEGLRAALAARRELPGLPVLILSQHVEQLYARELLADGAGGIGY
                     FLKESVFDADQFIDALERVAGGGTAMDPAVIAKLLSSGSSPRRLERLTEREHSVLGLMA
                     EGLSNQAIGQRLFLSDSAISKYTTSMFGKLGITDDDNSNRRVLAVLAYLNKT"
     gene            complement(5061..6314)
                     /locus_tag="HEK616_RS18475"
                     /old_locus_tag="HEK616_37700"
     CDS             complement(5061..6314)
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524875.1"
                     /locus_tag="HEK616_RS18475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37700"
                     /product="sensor histidine kinase"
                     /protein_id="WP_261954035.1"
                     /transl_table=11
                     /translation="MRKLGSWAADAGVGFVRACVVVAVSMLVPAGWAAVVLGVWWAGNP
                     WAWTAVFVWAAIGTLAVSRPLCRTVRRLVARWTGTVIPAGYRQAEPVVRMSTGYWWNGF
                     SYRRSSRDARQEQRWRLWWSDPATWRDLRFMAIAPLTMGVLAAVPPAGVAAAVLGLGQS
                     ELLVRLAGVLGLAVAVAGAPYAWRSVEPVAVRFLRPSPAMALADRVDELTAQRADTTVA
                     QAAEIRRIERDLHDGAQARLVSLGLSLATAEKLMETDPDRAKALMREARAGAATSLTEL
                     RELVRGINPPVLNERGLVDAVRALALDSPLEADVSADLRLRLDPPIESAVYFGVAELLT
                     NAVKHARATRARISLALDGTDLVVEVADDGRGGAVERAGGGLDGLRRRLAVFDGILEIS
                     SPAGGPTCARMVVPCESL"
     gene            6469..6966
                     /locus_tag="HEK616_RS18480"
                     /old_locus_tag="HEK616_37710"
     CDS             6469..6966
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009074518.1"
                     /locus_tag="HEK616_RS18480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37710"
                     /product="hypothetical protein"
                     /protein_id="WP_261954036.1"
                     /transl_table=11
                     /translation="MTTTRSTNDSSTQDNSTHGMGTTGHLTAATAHLHPPRTRRAFGTA
                     KKLVAAYGALSAAVLITVAVLALTGHQVTSFMWGRSGGVLASAAVIYWMTVLAARGTRW
                     AYLRVRILSVLMPIVIVGIDMIPGVCPPWFALIQAVSAVPLAAAAFLSNGSQLRAAFPK
                     GS"
     gene            complement(7053..9440)
                     /gene="metE"
                     /locus_tag="HEK616_RS18485"
                     /old_locus_tag="HEK616_37720"
     CDS             complement(7053..9440)
                     /EC_number="2.1.1.14"
                     /GO_function="GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019982020.1"
                     /locus_tag="HEK616_RS18485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37720"
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="WP_261954037.1"
                     /transl_table=11
                     /translation="MTETATGTGAGQSAAATVRATVYGYPRQGRERELKKAVEGYWKGR
                     VTADELRRTAAELRRANWRQLADAGIHEVPTGDFSYYDHVLDTTVMVGGVPERHRAAAE
                     ADPAPSSRPRPSAGCSLDGYFAMARGTQDVAPLEMTKWFDTNYHYLVPELGPGTVFRAD
                     PGKQVTELREALALGHRPRPVLVGPVTYLLLAKPAPGVAADFDPLTLLDRLLPVYAEVL
                     AELRAAGAEWVQLDEPALVQDRTPAELHAAARAYRGLGGLTDRPRLLVASYFDRLGDAL
                     PVLAGTPVDGLALDFTGAAAGNLDDLAAVGGLPGKRLVAGVVNGRNIWINDLEKSLATL
                     GTLLGLAGHVDVAASCSLLHVPLDTAAEHDIDPQILRWLAFARQKTTEVVTLARGLGRG
                     TETIAAELAANRADLASRAASPITRVPAVRARAAAVTDRDTRRSQPYDRRAAAQRAHLS
                     LPLLPTTTIGSFPQTGELRTARADLRAGRIDAVAYEERIKAEIQEVISFQEKAGLDVLV
                     HGEPERNDMVQYFAEQLTGYLATQHGWVQSYGTRYVRPPILAGDLARPEPMTVRWTTYA
                     QSLTGRPVKGMLTGPVTMLAWSFVRDDQPLADTARQVALALRDEVNDLEKAGTSVIQVD
                     EPALRETLPLRADARPAYLAWATEAFRLTTGGVRPATQIHTHMCYAEFGDILAAIEDLD
                     ADVISLEAARSHMQIAGELAEAGYSREAGPGVYDIHSPRVPGADEAAALLRKGLAALPP
                     ERLWVNPDCGLKTRGWAEVRASLENLVTAARTVRATLPASSS"
     regulatory      complement(9610..9839)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            complement(9855..12434)
                     /locus_tag="HEK616_RS18490"
                     /old_locus_tag="HEK616_37730"
     CDS             complement(9855..12434)
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606625.1"
                     /locus_tag="HEK616_RS18490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37730"
                     /product="GAF domain-containing SpoIIE family protein
                     phosphatase"
                     /protein_id="WP_261954038.1"
                     /transl_table=11
                     /translation="MGRSTVREETAERDDLLAAAVVKAVQGAGAYAGSIFLRSRDRRSL
                     VLAATCGVPPSQLGGWSLVPVSSPIPVAVAYGSGRTIHLADADETMRRFPQLAVALPYA
                     FGSCSVPVGAGGETFGALAVVWAAPPGSDGLTKTQRRHLRALANRLGASLAACRDRSGD
                     PLEGDARTAPVETPAPSAPAVRAGLFDWNLSASTLTADDDFCAIFGLDPGTFDARAETL
                     ASRLHPGDRAAFRAAARTAAAEGRIVSRTLRVREGAGAGPGGGAEGAGEGHGSGEGYRS
                     VVLWGRVPDLPDDDRARAHLVGVVVDARAGRAAAAAVERLRDGLFSLTPEGRVSYANRS
                     LEQLLDVRGEDLVGQCLWDALPWLSDPAIEYQHRSAMVSQTPTSFLVRRPPDQWLAFSL
                     HPDPNGVTGRVVPTGRPDAAPDLAEPPTVTAPPQPASAAAAPTPPAPSTTAAAAPARLG
                     VMYHVLQLGSALTEAVTTHQVCEVVAHQLLPAFGGQQLALYAVRDGTMHLIFHTGHHEG
                     FLDWLDGMPLRAPLPGTETLTSGIPLFIESQQSLSQGYPGIPIGGVNSWAYLPLIASGR
                     PAGTCVLGFDEIHHFTAKDRSVLTALAGLIAQALERARLYDSEFALARGLQQALLPHRL
                     PVLPDLRTTARYLPCTSGMDIGGDWYDVIPAAEGVALVIGDVEGHSIAAAATMAQLRSA
                     VRAFVAVGHAPGDVLAGANRTLIDLGTGLLASCCYLHLDPAGHRAWAVRAGHPPPLLRH
                     PDGHTDVLDLETGPLLGVDHASDYPRTPVDLPPGSVLALYTDGLVEERGTPIDVGIDHL
                     RSSLAHARAGSLDELADRLLQHAQRSSYRADDIALLLTEYRPAATGR"
     gene            complement(12557..13177)
                     /gene="lspA"
                     /locus_tag="HEK616_RS18495"
                     /old_locus_tag="HEK616_37740"
     CDS             complement(12557..13177)
                     /EC_number="3.4.23.36"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="lspA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003989609.1"
                     /locus_tag="HEK616_RS18495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37740"
                     /product="signal peptidase II"
                     /protein_id="WP_410011213.1"
                     /transl_table=11
                     /translation="MRRDIRTSRGPNVTDPGRGAAGGESERGGREARGTRRIPLLLMVA
                     CLAYAIDLFSKLAVVAKLEHHDPVNVIGTWLQLRVMRNSGAAFSMGSASTLVFTVIAVA
                     VALAIVRLARRLYSVPWAIALGLLLGGALGNLTDRLFRTPGQLQGAVVDFISVRGFSVM
                     NLADWAIVCGGVLIVFFTFRGRELDNAREAAADKESSSAPFRP"
     gene            complement(13343..14791)
                     /locus_tag="HEK616_RS18500"
                     /old_locus_tag="HEK616_37750"
     CDS             complement(13343..14791)
                     /EC_number="1.2.1.12"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948635.1"
                     /locus_tag="HEK616_RS18500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37750"
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="WP_261954040.1"
                     /transl_table=11
                     /translation="MTVNDDSFTNWINREEIAESMIPIIGKLQRERDVTVLLHSRSLVN
                     KSVVSILKTHRFARQIAGEELSVTETMPFLQALTTLDLGPSQIDLGMLAATYKADDRGL
                     SVAEFTAEAVAGATGANKIERCAPRDVVLYGFGRIGRLVARLLIEKAGSGNGLRLRAIV
                     VRGGGEQDLVKRASLLRRDSIHGQFQGTITVDEANSTIIANGNAIKVIYANDPSEVDYT
                     AHGIKDAILIDNTGKWRDREGLSKHLRPGVEKVVLTAPGKGDVPNIVHGVNHDTIKPDE
                     QILSCASCTTNAIVPPLKAMDDEYGVLRGHVETVHSFTNDQNLLDNYHKADRRGRSAPL
                     NMVITETGAASAVAKALPDLKAPITGSSIRVPVPDVSIAILSLRLGRETSREEVLDYLR
                     DVSLHSPLKRQIDFTTAPDAVSMDFVGSRHASIVDAGATKVDGDNAILYLWYDNEFGYS
                     CQVIRVVQHVSGVEYPTYPAPPAV"
     misc_feature    complement(14746..14764)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.88"
                     /tool="antismash"
     gene            15184..15612
                     /locus_tag="HEK616_RS18505"
                     /old_locus_tag="HEK616_37760"
     CDS             15184..15612
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677005.1"
                     /locus_tag="HEK616_RS18505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37760"
                     /product="VOC family protein"
                     /protein_id="WP_261954041.1"
                     /transl_table=11
                     /translation="MPYDQQHAHTSELPTTLARLNHTAVYASDRRLSAEFLAAILGLAV
                     SAPFGPFLPVDLGNGVTLDYFEKRDEPIQPQHYAFLVPDAQFDAMIARLEAVGVTYFAD
                     PHHTEPGRINRLFGGRGAYFADPDGHNMEIMTRPYARP"
     gene            complement(15668..17260)
                     /locus_tag="HEK616_RS18510"
                     /old_locus_tag="HEK616_37770"
     CDS             complement(15668..17260)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998340.1"
                     /locus_tag="HEK616_RS18510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37770"
                     /product="TIGR03086 family metal-binding protein"
                     /protein_id="WP_261954042.1"
                     /transl_table=11
                     /translation="MRVGEDTFWNIGEVARKTGLTVKLIRHWSDLGIVPPARRTPGGYR
                     LYGTEALARLQLARTLRGLGLGLATIRDVLEREDTLTQVAATHIDALEAQIRTLRSQQA
                     VLRSVIRRDTTAEGLTTMTELARMSDAERRTIIQDFVTETLGELDVPTYRRGLLAATPD
                     LPADPSDEQVDAWLELGALVQDPALRAGMRRMARYAADHRPGEHDPAALQAAERLTDDW
                     LRRVETARKQGIAPDSPAADPVVAAIVTAWIPTQTAPAGDPHPVGPVDDARARRLLLEQ
                     LEVASDPHVERYWHLLCLINGGTARPSMAAAGQWLRTALRANPTPGSRAAELHTMYDAD
                     AGQDTWGPAGVLQACDDVLNAVSRLVSAVVPAQFGQPTPCADWDVRTLLNHLVRENLLW
                     TALANGTPRSDFTADHLGDDHIEAFRLASRSTRSAFGRPGMLDQRYGPAPGRRLVEQVV
                     IEMLLHGWDLARAIGHPFDDVQHLAELALPVVQEIYGDLPRTDAGSFAPPQPAPEDASP
                     LDRLAAYLGRSIG"
     misc_feature    complement(17236..17249)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.97"
                     /tool="antismash"
     gene            complement(17295..18149)
                     /locus_tag="HEK616_RS18515"
                     /old_locus_tag="HEK616_37780"
     CDS             complement(17295..18149)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539049.1"
                     /locus_tag="HEK616_RS18515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37780"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_261954043.1"
                     /transl_table=11
                     /translation="MAAEQHPTGFHRDTFTHDGVTREVLRRGTGPAVIVMAEIPGITPK
                     VLDFAERVAAIGCTAVLPVLFGTPGRPADFAAGRRLKSATYVASSLGKVCVSREFTMLA
                     TGKSSPVVTWLRALAAHEHQRCGGPGVGAVGMCLTGGFALAMAVDERLVAPVLSQPSLP
                     LPVTRGRAGGIDISSEDLAAVRTRCARDGLQVMGLRFRSDRLVPGDRFAFLRRELGDAF
                     VAVELDDDAANPDAVLRPHSVLTEHLIDAPGQPTRAALDDVLDLFRNRLLEGHDTAPAT
                     PAG"
     gene            complement(18263..19642)
                     /locus_tag="HEK616_RS18520"
                     /old_locus_tag="HEK616_37790"
     CDS             complement(18263..19642)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004949668.1"
                     /locus_tag="HEK616_RS18520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37790"
                     /product="PAS domain-containing protein"
                     /protein_id="WP_261954044.1"
                     /transl_table=11
                     /translation="MDETGLKSLLQHLPVSWWEADRELRVIDSGGGAFDDTRTAQRFLD
                     TVTDQWQAVDQPHATDASQVTEHERAADHLPAGNHRRARFDGRLFDVNWPLDPPRQDRL
                     RGIAVEVSGEGRDPAPSPAPAVPLPAAARRYDAFADLAPAAAFIRDPDGRYLWANHAYA
                     HLYGTTPEHVIGKDVREVDAPADADRVLALDQEVLARGKPVRHTLTYHRADGATGHAAG
                     HRFPVREGTQTCVAGIYIDISDHTRALHQRQQAEENLYALRDHSGLPCALISAGGRILQ
                     ASAAAAELLQTRLSDLVGRRAHTLLAPAPELPALRKGWHALIARRSRRIQTSAVLVDGR
                     GRQRRAQLHLTTVGRGPSRAASVWAVITHQSLAHEPHPALTASQVRILSLLAAGRSNAE
                     IATSLRLSRQTVDYHLSRLRDILNAPTRCALVARAYVLGILAPQSWPPRSATAGHPQSA
                     T"
     misc_feature    complement(18707..18709)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            20001..21482
                     /locus_tag="HEK616_RS18525"
                     /old_locus_tag="HEK616_37800"
     CDS             20001..21482
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) other:
                     bacilysin"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537308.1"
                     /locus_tag="HEK616_RS18525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37800"
                     /product="acetyl-CoA carboxylase biotin carboxylase subunit
                     family protein"
                     /protein_id="WP_261954045.1"
                     /sec_met_domain="bacilysin (E-value: 8.8e-52, bitscore:
                     175.0, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTVLFVYAKGGPPLGYALSRVAARSAVHLLALSTLPPTVAASAE
                     RRCASVRTATGPERGDLVSLIVSRAQAVGADAVITFSEYAVVAVAEACEKLGLAGAGAS
                     CALARDKRLMRRTWGRRGISQPRFRPVADERELHDAAAELRLPLLLKAAWSAGSTAHRI
                     IRSAEEVPAAWQRAREVMAESAELGYAELHVADAGADFLVEEIVPGTAGGWFDQPGWGD
                     YVSVEGVVVDGVFRPVCLSGRMPTVEPFTERAGITPAALPTDAQQRVVALAREAVDALG
                     LENCGTHTEIKLGADGRMWVIETAARFGGAMTVPQIEEVFGLDLIGMLVDHLLGRPVTW
                     PARALTPQEARGAAGSFVVLAVDGAGDAWPDRRRWDFPTVRDAVPLSAGSRLSVVAENS
                     LPDGSPVPVYDPAAGANTMAALCLLSAADPETVLQDFRTLMDALPSVLPQAESHKETET
                     DAETKTETKTETKTEKAEKDEKDGQCKAETVEARS"
     gene            21479..23935
                     /locus_tag="HEK616_RS18530"
                     /old_locus_tag="HEK616_37810"
     CDS             21479..23935
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PPDK_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982642.1"
                     /locus_tag="HEK616_RS18530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37810"
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="WP_261954046.1"
                     /sec_met_domain="PPDK_N (E-value: 5.7e-32, bitscore: 110.0,
                     seeds: 105, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLAMTIATTTAPDPTAVDDSTAVDGHSTAEDRTAIGAQLALPLF
                     HTLCGTLAGHPYVKVVVDRVENTWHLLDAAVHPFHVDYIATRVLGMELAELDSCLDAFN
                     ASVYAAPERRFLLGVLSLHTDMGAGTAGAGTRIPTGRRARPFLVLETTEADTMSGPMLQ
                     EFYTFVRHRLDSRLPLLLKPANHGQEHALTAISDVRVPRILSHQLFGSRTRTPLNPGEA
                     VGRLRHFRTAREYEVYAAGAGTLGGSDIVAMPCLPDDVPRVAGFINTAPTTPLSHTNVL
                     ASGWGIPNAIIRDLDQLMEAEGLADADAWVRYEVRDDDIALVRLSQPPAPTLTPSPSPS
                     SAAGAQTSTMDASDPRPSHPIRLEPPLLHADIPALPLRQLRRTDQNRYGTKAANLGELH
                     HVLAGDTAEQPARAGLTGPAGPAGPAGPAGESSSRSVDLTAYYGRPRPPRADLYAHLTT
                     RLGLSGRPGLPDLPEGTRGAQLRAAARDFVRATVTAPDGIALPFALQHRFLTSSPAIQQ
                     AISELKAVLERETAVTVDVIDPLCRRLQDLVQHTAPMPDDVARAITAALRGLSSGPSGA
                     AGRLVVRSSSNAEDLPGFSAAGVYDSVTAVHGADELVAAVRQVWASLLSPRSVRLRHQA
                     GISPDDTYMGVIIQRYQPADLGGVLVTCNPTRRADFRNVYLNCSPGSPENVVDGTALPL
                     QYLYNTVEGGGRTVALGSSAEDLPAATRERLADLALTGRLLQSHFSGTAPSRVGSGDAH
                     VDVHRNVGADVDVDVDQNVGVDVDMGQNVGLDVDMAPDVDRPLDIEWLMTDQGAFHLVQ
                     IRPYAR"
     gene            23932..25413
                     /locus_tag="HEK616_RS18535"
                     /old_locus_tag="HEK616_37820"
     CDS             23932..25413
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359352.1"
                     /locus_tag="HEK616_RS18535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37820"
                     /product="MFS transporter"
                     /protein_id="WP_261954047.1"
                     /transl_table=11
                     /translation="MSGHLPGSRGLRRAGGRAKSSTDAPPLPPRARRIIRLNNGFQLLF
                     NLLWWMPVFYAYQRQAGLTDGQIFGIQSIYYTAFCLFEIPTGLVADRIGTRNCLRAGAV
                     VMTAANLAPVWAPSYTGFLVHFLLIAAGRSLTSGAASAYLYEGLRAEGAGAHYLKAEGQ
                     ARALGLAAKVLCWPLLGPLMAMAHSAPYVLSAASAGGSLVCAVLLPRQAAAVPAAGRKR
                     ATSHEAAAALRAVRSTPWLALVMVQGVALFTLSRICQVNLFQPVLLDHGIGESSHGTVL
                     AAMTVAEAVASARPQWLTSRLSPVAWVSLLSLAMAAALAGSTLGGPWTTVALLCVFAAV
                     TGLASPLQRKLVNDAVPAGAPRATLLSVESLVDRAVCALAAVAAGAYLSAHRLDALLWH
                     SALATAVLLAVLHLLLRRHHGRARTAEGGAHRETRGIRAEDGRAHTESRGVRTAEGGTE
                     SPGAPSAEGGVHTEGGRAETGRTDEIRPVATAGKP"
     gene            25625..26341
                     /locus_tag="HEK616_RS18540"
                     /old_locus_tag="HEK616_37830"
     CDS             25625..26341
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020114728.1"
                     /locus_tag="HEK616_RS18540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37830"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_410011214.1"
                     /transl_table=11
                     /translation="MSTARLTALGAGPGWHCLDVGAGTGTIARWLVESADVTSVLAVDR
                     DTRFLTADAPPGLVAQTADVTALDFDPGRFHLVHARFVLMHLRPWRRMINQLSSLLAPG
                     GVLVLSDAVDLTTSSAPATPYTRVMRAMWQALRTTIGTDTSWVPDYPSFLLEEGLHSVA
                     AEIHVPPLLPGSPISRFWEDTWQRTHDAILATGQVDEPQLEQARRSLSSPHSAALSPGM
                     LTAWGWKPRHTASPPP"
     misc_feature    26464..26478
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.7"
                     /tool="antismash"
     gene            26528..27106
                     /locus_tag="HEK616_RS18545"
                     /old_locus_tag="HEK616_37840"
     CDS             26528..27106
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016905658.1"
                     /locus_tag="HEK616_RS18545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37840"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_261954049.1"
                     /transl_table=11
                     /translation="MYAIPLGDDGANGGSRAELRPLEPWQAEEFLAHIDRGREFIGQYI
                     GLADLIVDLDASRAYLHSYVEKAAADTGRLCGIWLDGRLVGGVLFRTMDVHQGTAEAGC
                     WLEPSAAGKGLVTRAVRVLIDWAVEERGIHRVEWLVAAGNEPSIAVARRLGMTKDGVLR
                     ESYLYRGRRHDIEVWSVLAPEWRAAKRGA"
     gene            complement(27188..27907)
                     /locus_tag="HEK616_RS18550"
                     /old_locus_tag="HEK616_37850"
     CDS             complement(27188..27907)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546700.1"
                     /locus_tag="HEK616_RS18550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37850"
                     /product="hypothetical protein"
                     /protein_id="WP_261954050.1"
                     /transl_table=11
                     /translation="MEERDSLEVTPGGALRTPRAAGAAGVLAALLLAAVLMIIRISLPS
                     PIPARAGEWPSRSSHRQILEVALGLLPFAGIFFLWFMGAVRDHIGRTERDIGRPANAGS
                     GTEEERAENRFFATLFLCSGLMFTALVLAAGAAAGGLLAITGNVPAGAQDLWTYGRATL
                     TLLASYAMRMAAVFTLSTTTIGLALRVFPRWLAWLGYAAALVLLFVVGSVPWTELVFPL
                     WMLATSTYILMVSFRTR"
     misc_feature    28086..28100
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.87"
                     /tool="antismash"
     gene            28141..28599
                     /locus_tag="HEK616_RS18555"
                     /old_locus_tag="HEK616_37860"
     CDS             28141..28599
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576953.1"
                     /locus_tag="HEK616_RS18555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37860"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_261954051.1"
                     /transl_table=11
                     /translation="MPDRFYSVEQVAEHLGLHVRTIRNYVRDGRLHAVRIGKQYRIAHE
                     DLEAFTGRPAPAPPGDADERRPHQQKQQKQQHTEVCSIVEIDAITPERVDRLTNLLMSV
                     ATDRGPGHAPLRIETAHDKERARLKVIVLGGLADTARVLECMDGVLAT"
     gene            28634..29503
                     /locus_tag="HEK616_RS18560"
                     /old_locus_tag="HEK616_37870"
     CDS             28634..29503
                     /NRPS_PKS="Domain: Abhydrolase_1 (61-276). E-value:
                     1.7e-18. Score: 59.0. Matches aSDomain:
                     nrpspksdomains_HEK616_RS18560_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576954.1"
                     /locus_tag="HEK616_RS18560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37870"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_261954052.1"
                     /sec_met_domain="PF00561 (E-value: 8.9e-12, bitscore: 43.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.4e-13, bitscore:
                     50.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSASTNAPTSTSTIYKTEAGAREIQQRYREMLQDWPVPAEEVRIP
                     TREGETFVLASGPKDAPPVLLLHGSGANTTMWLDDIASWSQHFRTYALDLIGEPGLSAP
                     SRPPLSSDAHALWLDEVLEYLGVSRTAIVATSLGGWVALDYATRRPDRVTRLALLCPGG
                     VGRQKVAWLFKAVLLRAVGRRGVRRSTAAVTGLSAPETQHLLDHVMLTFTHFKPRTERL
                     PLFPDSALRRLTMPTLVTVGSRDAMFDSEGTVRRVRQCLPHATVNVLPEAGHALLNQTD
                     SVLTFLRG"
     aSDomain        28817..29461
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEK616_RS18560_Abhydrolase_1.1"
                     /evalue="1.70E-18"
                     /label="HEK616_RS18560_Abhydrolase_1.1"
                     /locus_tag="HEK616_RS18560"
                     /protein_end="276"
                     /protein_start="61"
                     /score="59.0"
                     /tool="antismash"
                     /translation="PPVLLLHGSGANTTMWLDDIASWSQHFRTYALDLIGEPGLSAPSR
                     PPLSSDAHALWLDEVLEYLGVSRTAIVATSLGGWVALDYATRRPDRVTRLALLCPGGVG
                     RQKVAWLFKAVLLRAVGRRGVRRSTAAVTGLSAPETQHLLDHVMLTFTHFKPRTERLPL
                     FPDSALRRLTMPTLVTVGSRDAMFDSEGTVRRVRQCLPHATVNVLPEAGHAL"
     gene            30100..>30930
                     /locus_tag="HEK616_RS18565"
                     /old_locus_tag="HEK616_37880"
                     /pseudo=""
     CDS             30100..>30930
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670826.1"
                     /locus_tag="HEK616_RS18565"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37880"
                     /product="alpha/beta hydrolase family esterase"
                     /pseudo=""
                     /sec_met_domain="Peptidase_S9 (E-value: 8.1e-12, bitscore:
                     43.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYVYRPPQLPLHPAVVVALHGCTQSARIYADNSGLTTFADRYGFL
                     LVFAETTSANNPGQCFNWFQPLDNQRGQGEAASIRQMVAYANTAYGTDRSRTYVTGLSA
                     GGAMTSVMLATYPDVFTAGAVVAGLPYNCTKDTGPFTCMNPGVDGTPAAWAQRVRDAYP
                     SYSGPWPRVAIWHGDNDTTVAPRNADELRDQWTAVHGLSQTPDRTSTIGPNATRSQEYL
                     ATDGTVAVQVNKVPGIGHGTPVDPGTGPQQCGRTGTANFIASICSSYWITKFFNL"
     misc_feature    30130..30132
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(30936..31829)
                     /locus_tag="HEK616_RS18570"
                     /old_locus_tag="HEK616_37890"
     CDS             complement(30936..31829)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145722.1"
                     /locus_tag="HEK616_RS18570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37890"
                     /product="EamA family transporter"
                     /protein_id="WP_315975424.1"
                     /transl_table=11
                     /translation="MPAPGLVMGGVLGLQCGAALTTRLYPVVGPAGVVSLRLCLAAVVL
                     TALWRPGLRWDRTTLGVAAAAGTLLAVHHLSYYEAVDRLPLGAATTMEFLGPFAIALFG
                     SRRAADLLWACLAAAGVVLLSHSGIPLDTAGLACALLAGCCWGGYILVGKRLAERVPDG
                     RGLALAVTWGALLSLPYGIAQAGSRLLEPTTLALAAVVAILSSVLPYTFHLEALRRLPP
                     RTFGVLTSLEPAVGALIGLVLLGQHLAVPQWAGVLAVALASIGATRAPGRAGPRRRVGS
                     SVDGHVRARQSREPPC"
     misc_feature    32082..32098
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.77"
                     /tool="antismash"
     misc_feature    complement(32148..32164)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.16"
                     /tool="antismash"
     gene            complement(32279..32965)
                     /locus_tag="HEK616_RS18575"
                     /old_locus_tag="HEK616_37900"
     CDS             complement(32279..32965)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016436764.1"
                     /locus_tag="HEK616_RS18575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37900"
                     /product="Clp protease N-terminal domain-containing
                     protein"
                     /protein_id="WP_261954054.1"
                     /transl_table=11
                     /translation="MDDLIAEVDRTCDAAHRPGGQEQPDWLALLTVAANLAGQLQALAD
                     DLVEDYVEHCRMHGSSWTDIGTALGVTRQAVQQRFQAPHKRYGPETMTDDLRQAMVHVK
                     QAAVHHRNNYIGTEHLLWGLTAEDNTATRLLRAADVSPEDLHKAVGARLSMGASQAAER
                     IAWTPYSRKAIAIAEERAEAAGSAGIDCDHLLLGLAQIGRGVAAGVLSEAGVDAATLDG
                     RPRLCG"
     gene            33141..34382
                     /locus_tag="HEK616_RS18580"
                     /old_locus_tag="HEK616_37910"
     CDS             33141..34382
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEK616_RS18580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEK616_37910"
                     /product="hypothetical protein"
                     /protein_id="WP_261954055.1"
                     /transl_table=11
                     /translation="MITNEPPHLPSPDVLWSHAATLAAWSSEQQLPVHNYRLDETGLRS
                     ADVGNGWWALSWVEGGRAVLYGIDHDYSDTVGLAPPVDLLADGPSWLPWQWLDDVITGG
                     EEIGFVYWWDGREWARAPHPVEVHDDGVHSMVPADDSEVRQVCDALVTDGADPAAVRER
                     EAAHRRTAAAPVPNGAAVLPAGQGEPTDRRVPCWLPEQHAAVLAVEMRAATELNRPAPP
                     ATPERDRLIAWLRANGPRTEGSSALSATFVDAEDTDYGRGADGFLDVLGRRIFGEAATL
                     LAALRNAEADPERGRWLYIRITVTNSDTDSDIDTGTGTNTTSTIERGYDCLPDWWPARR
                     GIVATLPHTVRLEMARRAAHWRPNWASLLDEDIRRDGTPARLCRVELAPPHISAANAHA
                     DAHMNAAADAEPGS"
     gene            34398..34718
                     /locus_tag="HEK616_RS18585"
                     /old_locus_tag="HEK616_37920"
     CDS             34398..34718
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140618.1"
                     /locus_tag="HEK616_RS18585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37920"
                     /product="hypothetical protein"
                     /protein_id="WP_261954056.1"
                     /transl_table=11
                     /translation="MVRWPGAPEDVERGHHVEWTVEEDIAWAGNTRPTADTTPALHEDG
                     DQIVLRGRLNLTGDGAAFLDLGSGTQILFDLADPPPPDEVHGTWVEIRVRRESVSLWPY
                     LV"
     gene            complement(34887..35141)
                     /locus_tag="HEK616_RS18590"
                     /old_locus_tag="HEK616_37930"
     CDS             complement(34887..35141)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575786.1"
                     /locus_tag="HEK616_RS18590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37930"
                     /product="hypothetical protein"
                     /protein_id="WP_261954057.1"
                     /transl_table=11
                     /translation="MTPPYAFPEDLVQAQRAWYTAYRELSCEENPSQTTVLRRRLQQLS
                     VRIATHPYWASIPGRAPAARMALKQQTWELEPEPEEVRP"
     gene            complement(35238..35891)
                     /locus_tag="HEK616_RS18595"
                     /old_locus_tag="HEK616_37940"
     CDS             complement(35238..35891)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523077.1"
                     /locus_tag="HEK616_RS18595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37940"
                     /product="hypothetical protein"
                     /protein_id="WP_261954058.1"
                     /transl_table=11
                     /translation="MTHPDTTPKPDDAPSPSDPRRPDATRGLNLFLGFAPWIIFAVVAS
                     PSSWGFAALAALITAIGASIPDIRRRSLKILDIAGMLFFAVICTLSLVLDRHALIWLET
                     YAQTLSAGVLAVVALTSLAFMPFTEQYARESVPRAYWGSPLFRHVNRVLTAVWGAVFLV
                     TALLGVLALHTTSGADWLNWIIPIALLVGAVRFTRWYPDQARARAQRSAASAAT"
     gene            36266..37768
                     /locus_tag="HEK616_RS18600"
                     /old_locus_tag="HEK616_37950"
     CDS             36266..37768
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557875.1"
                     /locus_tag="HEK616_RS18600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37950"
                     /product="DUF4419 domain-containing protein"
                     /protein_id="WP_261954059.1"
                     /transl_table=11
                     /translation="MAYEIDLPLDEQGGKGGERREDAAGEVGRAAGEVDRADNEAAGLA
                     AELTELGNDGFLRATLRDQPPAHFHHRSTDHLLGWPSGAPDIAEPTSSLLLRALHTCFT
                     AHLPLSLSPDVLWYAVVHEVAVHIRLNPETYEGIFTETPGHRQTIVVRDDSAPLDWERS
                     INLVQQPLRARIGDEVADLFQPTFSTTTDTDATAMLVALMDVVSPYYRFRWQTLCGIPR
                     IRLEGTDRDWRLLAARVRELAEWFEGLRPWFTALQPVLDAIWATASGWGVDLDFWRSLY
                     KWESASGGDRVTGWITAFFAHRYTDDGPRPKPSFGPGTTAEDDFPSHVSQVPFRWETPT
                     GTLDMAFLGGILGIEREGEWIRPQLGHVVAELAPTTKPSPNAKPATEPDGAPHAEPDGE
                     RADRPYADARLPEPWTWADVQRLTGCPQAHPLTTIGTVTHNGSPLQVDYAINLNGICAV
                     RAGDRNDDGDGNWYLGDVVSDAGDIQCWASYGPDLGDALRAL"
     gene            complement(37782..38723)
                     /locus_tag="HEK616_RS18605"
                     /old_locus_tag="HEK616_37960"
     CDS             complement(37782..38723)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511381.1"
                     /locus_tag="HEK616_RS18605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37960"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_261954060.1"
                     /transl_table=11
                     /translation="MDRDTAMDTGAAMNRAAEGAAERTVLVIGATGNVGRQVVTQLLAT
                     DVGVGVHVRALTRHPDSAGLAYGGVEVRAGDLADARGLEEALEGVDRAFLMWPFHTADA
                     APAVVDALRRHVEHVVFLSSGAVQDGLAPGQQRHPVGRSHAAVERLIERSGLGWTHLRP
                     STFASNTLWWADQIRTGDVVRGAYGAVPMALLHEADIAAVAVRALTEEGHDKAVYTLTG
                     PEILTQVDQVRIIGEAIGRPLRWEELSREAARQQLLADDTFPDSFVDTLLDGYAEMLDA
                     PRPVTTTTVEEVAGGPARTLHQWAVDHAADFR"
     gene            complement(39013..40089)
                     /locus_tag="HEK616_RS18610"
                     /old_locus_tag="HEK616_37970"
     CDS             complement(39013..40089)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676313.1"
                     /locus_tag="HEK616_RS18610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37970"
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="WP_261954061.1"
                     /transl_table=11
                     /translation="MNRDVTLHDLIVAGAALIAGIVAGLLCKAVLRWLGKHASRTRWSG
                     DDVIVDSLRSVVPWAAISGGLAAAAAALPLTPTVGRNVNRTLTVLLILVVTLTAARMIT
                     RLVRSLAQSRSGVAGSATIFANITRIVVLAMGVLVILQTLGISIAPLLTALGVGGLAVA
                     LALQDTLANLFAGVHVLASKTVQPGDYIRLSSGEEGYVVDINWRNTVVRQLSNNLVIIP
                     NAQLAGTNMTNFTRPEQQLSILVQVGVGYDSDLEHVERVTLEVVKSVMTDVSGAVPEHE
                     PAVRFHTFGDSRIGLTVILGVGEFSDQYRIKHEFIKRLHQRYRDEGIRIPAPTRTVALQ
                     QPEGVAIPQQRGTSDPVL"
     misc_feature    complement(40064..40077)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.97"
                     /tool="antismash"
     misc_feature    complement(40272..40292)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.23"
                     /tool="antismash"
     gene            40611..40892
                     /locus_tag="HEK616_RS18615"
                     /old_locus_tag="HEK616_37980"
     CDS             40611..40892
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662246.1"
                     /locus_tag="HEK616_RS18615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37980"
                     /product="DUF6355 family natural product biosynthesis
                     protein"
                     /protein_id="WP_261954062.1"
                     /transl_table=11
                     /translation="MRRFAALMLGAAAFCGAVTAAPGQAIALAKEPCGFYKTGSDAYYR
                     HCTTDGSNVVIKVEVAWAPDYQRCVGPGRTWLGSASRIQGAHYVGRTC"
     gene            complement(41029..41301)
                     /locus_tag="HEK616_RS18620"
                     /old_locus_tag="HEK616_37990"
     CDS             complement(41029..41301)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019075952.1"
                     /locus_tag="HEK616_RS18620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_37990"
                     /product="hypothetical protein"
                     /protein_id="WP_261954063.1"
                     /transl_table=11
                     /translation="MGKGMGRWPTVDLDSGVEDATLLILEWLGEQGIGAMIRIDAERLR
                     EGRPAWTFAAGGGPLPPMRADGASVAECMGRALSRMREAGVAVPF"
ORIGIN
        1 acaggaccag gccgcggacg aagctcgcgc cctggccgtg ccggacggcg gcgggggtga
       61 agccgttgcg ggcgcacgtg gtcagcaggt cgtcgtagag cgtcggggcg ctgctgcggg
      121 ggaagaggat caggtcgtac ccgctgagcg aggcgagcgg cacctcgtcg agcgcggccg
      181 cggcggcgct gcgcggcagc agtacgccca actcgcggcg caggaccggg cccagctcca
      241 gaccggtgac gtcgcagggg tggtggatga cgccgacgtc caggtcctgc gaggcgaacc
      301 gggcgagttg ctgagccgtg gacagctcgt gcagttccag ttccaggccg gcatggtgcc
      361 gggggaagtc cgccagcacc gcggcgacgg tctcgccggc gaggtcgggc agcagggcga
      421 cgcgcagcag gccggtctcg ccgtcccgga tgcggcgggc ggtggccatg aacgcctcgg
      481 agcgggcgag gagttcccgc gcctcggcca gcagcagcgt cccggcttcg gtgatcgtca
      541 cctgccggct ggtgcgctcg aacagccgga cccccaactc ccgctccagc cgctggatgc
      601 gctgcgacag cggcggctgg gcgatgccga gctcggccgc ggcacggccg aagtgtgact
      661 gttctgcaac agccacgaag cactccagat gccgaaccag gtccatggcc agcgatcata
      721 tcaagaattg atcgatccga gatcgatatc ggtcttggac aggatgcggc gggcattgct
      781 ctcctcggga catggatgcc ttccccacac tgcgtcgcgg ccgccccgtc cgcgcctggt
      841 ccctcgccct cgccctgctg ctcgggccgg cactcgccgg ttgcggtgcg accgggcagc
      901 cggcgtcacc gaccaaggcc gccggctccc cgtccgccaa ggccgatgcc acccaccggc
      961 aggtgcgggt ggacggccgt acgcgggagt acctgctgca ccgccccacc gcgcccggcg
     1021 gccggacccg gcccctggtc atcgccttcc acggccgcgg ctccaccgcc tcgtacctgc
     1081 gcgagcagag ccgcctggac gaggacgcca gggcccgcgg catgctgatc gcctatcccg
     1141 agggtctggg caagctgtgg ggcgccggca cccgggcgac cgagcggcgg ccggacccgg
     1201 acctcgacgt gcggttcacc aaggcgctca tcgccgaact ggtgcgcacg gagcgggccg
     1261 accccaagcg ggtctacgtc gtcgggttct ccaacggcgg ctcgatggcc ctgcgcgtgg
     1321 cggcccagag ccccgggctg ctggcgggag cggccgcggt gtccggcgaa ctccccacgg
     1381 gcgacgccgc ggtcaagccc accggtccgg tgcccctcat gatcatttac ggtgccgccg
     1441 atcgcgtgcg cccgctcgcc ggaatgcccc acccctcccc cgcccccgcc ggcgaggaac
     1501 cggtcacccc gaccatgtcg gcccgggaca gcgccgccgc gttcgcgacc gcgggcgggg
     1561 cgaccgccgc ggccaagacg aaggccgagg ccggctacga ccgcaccgtg tggcgcctca
     1621 aggcccccgg agcgaccgtc cagctcctcg tcatgcacga cgcgggacac acctggccgg
     1681 gctcacgcat caagccgccg gcgggcttcg gacccaccag cacggcgctg aacgcgacca
     1741 gcacgatcct cgatttcttc cacctctgaa gaccggcgtc cggcccgccg cgccctcccg
     1801 accaccctgc cagccaagga ctttccgatg ccccgatccc gatacccggc ccccgccacc
     1861 actcgccgtc gcacaccgcg ccccgtggtc cgcaccgtca cctcggtggc ggtggtgagc
     1921 gcggtcgtcg cgggcggttc ctacgcggcg gggctcggcc ccttcgcccg gggcgccacc
     1981 gaacccgagc ccgcggccct ggcccaggct catggcttcc tcgcggactg ggccgccggg
     2041 cgcctgccgg ccgcggccgg ccgcaccacc agtcccacca cggcgcagca cgtgctgcgg
     2101 aacttcaccg ccgggctcga catccgccgt ccgacgctca cggtcgcggc gccgcccatc
     2161 cgggccgagg acgacaccgt cgacgtcccc ttcaccgcca cgatgcccat agccgacctg
     2221 ggcacctgga cctacaggtc gaagcttccg ctgcgccagc agggcgacgg gagctggaag
     2281 gtggactggt cgctgtcggt cgtccacccg cggctgagcg gggccaagag gtttcacctc
     2341 gaacgcgagg caccggtcgc cacccccgac gtcaccgacc gcaagggcgc ttccctgtcg
     2401 ggcgccaggt tcccctcgct gaaccccgtc ctgaaccagc tcgaccccgg tacgggcggc
     2461 ggcgccccgc gcggggcgat ccagctcgtc gaccgggcca ccgggaaggt cgaacgcacg
     2521 gaggccacct tcgggaagaa gcccgtccgg tcggcccgcc ggcccgtccg tacgacgctg
     2581 gacgccacct ggcaggccgc cgcggagcgg gccctcgcct ccggcgccca cggcaggaac
     2641 gcctcgctgg tcgccctccg gatcgacaac ggcgagatcc tcgcgatggc caactccccg
     2701 tcgtccggct tcaaccgcgc cgtctcgggc acctatgcgc ccggctccac ctggaagatc
     2761 gtcaccagca gcgccctgct gctcaagggc gccgtcgcgc cctccgacgt cgtcgactgc
     2821 cccaagtacc tcacggtggg caaggagttc cacaacgtgg agacgtccga acaccgcaac
     2881 gcgaccttcc tgaaggactt caccgagtcc tgcaacaccg cgttcatcag cctgcgcggg
     2941 aagctcggca accgggaacc gggcgacgtc gccggcaggt atttcggcgt cggccagaag
     3001 tggcacgtcg gcattgcctc gtacgacggg tcggtgccgg cgccgcgtga cgagaccgag
     3061 aaggccgcct cgatgatcgg gcagggcagg gtccaggcca acccgctgat catggcgtcg
     3121 gtcatcgcca ccgcggtctc cggcaccttc caccagccct cgatcaccca caggaatcag
     3181 gacccgacga ccaccacgcc gctgccgcgc aaggtcgtca cccaactccg cgcgatgctg
     3241 cgcaccaccg tcacggacgg cacggcccgg atcctgtccg gtctgcccgg cgaggtcggc
     3301 gcgaagaccg gcaccgccga ggtgtccgac gacgaaccca acaacggctg gctcgcggcg
     3361 caccgcggca atgtcgccct cgcctgcgtc gtcgaacagg gggtgaccgg tggcggttcg
     3421 gccggtcccg tcatccgcga cctgctgacc gccgttccca ccgatccctc atgacggcgc
     3481 cggcgccgct cagaagtccc gtccgtccgc gaccatgttg taggcctcgt cgtcgaaggg
     3541 gccgtggaat tcgccctggg cgtcgccgag atcgacgtcc gtggtcgggt gggcgacccg
     3601 cagccgctcc atcatggggt cggacagata gtggtgatgc aggtccagcc gctccaggtg
     3661 gtccagcggc tgcccgttga gcagggcttc cgcgccccgg tcggtgagcg ttcccagggc
     3721 caggctcagc gaccgcagac ggggtaccac ggccgcctcg gcgacctcct cggcgatctc
     3781 gtcctggagc gcgctgttct gaaggcccag ggaccgcagc gcgggcagcc gctcaccgct
     3841 caggaccggc gccaggtcgc acacgtcggc cacctcgccc gtgccgtcat cgacaccgag
     3901 ccagaggtcc aggcgttcca gcccgggcag gtcgctggcc gccaccgccc gcatcacgtc
     3961 cgacggcaga cagcaggact cgcagcgcag cgtcttcagt gcggcatgcc ggaaagggct
     4021 cagctcccac ccctgctttc cccgcacgtc cagcctctcc agcagcggga agcgttcgag
     4081 gacgggtgtg aggtcggtct ggtatatgca gaagaagtcc ggttcgtcgc cgaggaacag
     4141 cgcctccagt cgggggaacc gctccgcggc gtcgagcagg tgggtggcgg cggccgggcc
     4201 gtcgaagccc gtgaacccca ggatcagggt ggtcacctgg gtggtgtcga cggtctgcac
     4261 gaagcgctcg aagacctcgg ggaattcggg cggccccgag atcgccgcgt cgagacgcca
     4321 ggccgttcct tgcgggtcgg tacggacagc gcggtccggg tcgaactcca ccaccggccg
     4381 gccgtggaac tgcctggtgc gctggtgtcc gtacatcgat gctcccgttc acgtcttgtt
     4441 cagataggcc aggaccgcga ggacgcggcg gttgctgttg tcgtcgtcgg tgatgccgag
     4501 cttgccgaac atggaggtgg tgtatttgct gatggcgctg tcgctgagga agaggcgctg
     4561 gccgatggcc tggttggaca gtccttcggc catcaggccg agcacggagt gttcgcgttc
     4621 ggtgagccgt tccaggcggc ggggcgagga accgctggag agcagtttgg cgatgacggc
     4681 cgggtccatc gcggtcccac ccccggcaac gcgttccagg gcgtcgatga actgatcggc
     4741 gtcgaagacg ctctccttga ggaaatagcc gatgccgccg gcgccgtcgg ccaacagctc
     4801 gcgggcatac agctgttcca cgtgctggga gaggatcagg accggcagcc cgggcagttc
     4861 cctgcgggcg gcgagggccg cccgcaggcc ctcgtccgac tgcgtcggcg gcatgcggac
     4921 gtcgacgacg gcgacgtccg gccgccacga caccagcgca tcgagcgtct cgggcccggt
     4981 ggacgcggtc gccaccacct ggtgtccgta tgcctcgatg aggcggacca tcccgtcgcg
     5041 caggaggtag aggtcttcgg ctacaacgat tcgcatggca ccaccattct tgcgcaggtc
     5101 gggccgcctg ccggactgct gatctccagg atgccgtcga agaccgcgag acggcggcgc
     5161 agcccgtcga gtccgccgcc ggcgcgctcg acggcaccgc cgcggccgtc gtccgccacc
     5221 tcgacgacga ggtcggtgcc gtccagggcg agggagatcc gggcccgggt cgcgcgggcg
     5281 tgcttgaccg cgttggtcag cagttcggcg acaccgaagt acacggcgga ctcgatcggc
     5341 gggtccaggc ggagccggag gtcggcgctg acgtccgctt ccagcgggct gtccagggcg
     5401 agggcgcgca cggcgtcgac gagcccccgc tcgttgagca ccggcgggtt gatgccccgg
     5461 accagttcgc gcagctcggt cagtgacgtg gcggcgccgg cccgtgcctc ccgcatcagc
     5521 gccttggccc ggtcggggtc ggtttccatc agcttctccg cggtcgccag ggagagcccg
     5581 agcgagacca ggcgggcctg cgcgccgtcg tgcaggtccc gctcgatccg gcggatctcg
     5641 gcggcctgcg cgacggtcgt gtccgcgcgc tgggccgtca gttcgtccac ccggtccgcc
     5701 agtgccatcg cgggcgacgg gcgcaggaag cggacggcca ccggctcgac ggaccgccag
     5761 gcgtacgggg cgcccgcgac ggccaccgcc aggccgagca ccccggcgag gcgcacgagg
     5821 agctccgact gcccgaggcc gaggaccgcc gccgcgaccc cggccggcgg gacggccgcg
     5881 agcacaccca tggtgagcgg cgcgatcgcc atgaaccgca ggtcgcgcca ggtcgcggga
     5941 tcgctccacc agagccgcca ccgctgctcc tggcgggcgt cccggctgct gcgccggtag
     6001 gagaacccgt tccaccagta tccggtggac atccgcacca ccggctcggc ctgccggtac
     6061 ccggcgggga tgacggtgcc cgtccacctg gcgacgagcc ggcggaccgt ccggcacagc
     6121 ggccgggaca cggcgagcgt gccgatcgcc gcccacacga acaccgctgt ccacgcccac
     6181 gggttccccg cccaccagac ccccagcacg acggccgccc acccggccgg caccagcatg
     6241 ctgacggcca ccaccacgca cgcccggacg aaccccaccc cggcatccgc cgcccacgac
     6301 cccagttttc gcatgaccat cccttgtcgc ttctcgttgc cagtgcgtcc actgtgcgct
     6361 gcccacagcc tgatccccgc cggttcggcc cggtagtggg tctggcccca ctcaccagta
     6421 cgtccaggct cataccgggc cgctcgtgcg ctccctagcg tcgacaccat gacgacgaca
     6481 cgcagcacga acgacagcag cacgcaggac aacagcacgc acggcatggg caccaccggc
     6541 cacctcacgg ccgcgacggc ccacctccac cctccgcgca cccggcgggc cttcggcacg
     6601 gcgaagaagc tcgtcgcggc ctacggtgcg ctcagcgcgg ccgtcctcat cacggtcgcc
     6661 gtcctggcgc tcaccggaca ccaggtgacc tcgttcatgt ggggccggtc gggcggggtg
     6721 ctcgcgagcg ccgcggtgat ctactggatg accgtactcg ccgcacgggg aacccgatgg
     6781 gcctatctcc gggtgcgcat cctctcggtc ctcatgccga tcgtgatcgt gggcatcgac
     6841 atgatccccg gcgtctgccc gccctggttc gccctgatcc aggccgtctc cgcggtcccc
     6901 ctcgccgcgg ccgctttcct cagcaacggg tctcagctgc gcgccgcctt ccccaagggc
     6961 tcgtaggaaa ggctcttccg gcaatgcggt cggggcccca cgtccggcgc gttgccgtgc
     7021 cgcagcggac gtggggcccg ctcaccgggt gctcaggagg agctggcggg aagcgtggcg
     7081 cggacggtgc gggccgcggt gacgaggttc tccagggagg cccgcacttc ggcccaaccg
     7141 cgggtcttca ggccgcagtc cggattgacc cacagccgct cgggcgggag cgccgccagc
     7201 cccttgcgca ggagcgccgc cgcctcgtcg gcaccgggga cgcggggcga gtggatgtcg
     7261 tagacgccgg gcccggcctc gcgggagtag ccggcctcgg cgagttcgcc ggcgatctgc
     7321 atgtgggagc gggcggcctc caggctgatg acgtcggcgt cgaggtcctc gatggcggcg
     7381 aggatgtcgc cgaactctgc gtagcacata tgggtgtgga tctgcgtggc cgggcgtacg
     7441 ccgccggtgg tcagccggaa cgcctcggtg gcccaggcca ggtaggccgg gcgggcgtcg
     7501 gcgcgcagcg gcagggtctc gcgcagcgcg ggctcgtcga cctggatgac cgaagtcccg
     7561 gccttctcga ggtcgttgac ctcgtcgcgc agggccaggg cgacctgccg ggcggtgtcg
     7621 gcgagcggct ggtcgtcgcg gacgaaggac caggcgagca tggtgaccgg gccggtgagc
     7681 atgcccttga cggggcggcc ggtgagcgac tgggcgtacg tcgtccagcg cacggtcatg
     7741 ggttcgggac gggcgaggtc accggcgagg atcggcgggc ggacgtagcg ggtgccgtac
     7801 gactggaccc agccgtgctg ggtggcgagg tagccggtga gctgctcggc gaagtactgg
     7861 accatgtcgt tgcgttcggg ctcgccgtgc accaggacgt cgagcccggc cttctcctgg
     7921 aaggagatca cttcctggat ctcggccttg atgcgctcct cgtaggcgac ggcatcgatg
     7981 cgccccgccc tcaggtccgc cctggcggtg cgcagttcgc cggtctgcgg gaaggagccg
     8041 atggtggtcg tcgggagcag cggcagcgag aggtgggcgc gctgcgcggc ggcccgccgg
     8101 tcgtacggct gcgagcggcg ggtgtcccgg tccgtgacgg ccgcggcccg ggcgcgtacg
     8161 gcggggacgc gggtgatcgg cgaggcggca cgggaggcca ggtcggcacg gttggcggcc
     8221 agttcggcgg cgatggtttc cgttccccgg ccgaggccac gggccagggt gacgacctcg
     8281 gtggtcttct ggcgggcgaa ggccagccag cgcaggatct gcgggtcgat gtcgtgttcg
     8341 gcggcggtgt cgagggggac gtgcaggagg gagcaggacg cggcgacatc gacgtggccg
     8401 gcgagtccga ggagggtgcc gagggtggcc agcgacttct cgaggtcgtt gatccagatg
     8461 ttccggccgt tgaccacgcc ggcgaccagc cgcttgccgg gcagtccgcc gacggcggcg
     8521 aggtcgtcga ggtttccggc cgcggccccg gtgaagtcca gcgcgagtcc gtccaccggg
     8581 gtgccggcca gtacgggcag cgcgtcgccg agccggtcga agtacgaggc gacgagcagt
     8641 cggggccggt cggtcaggcc gccgagaccg cggtaggcgc gggcggcggc gtggagctcg
     8701 gcgggggtgc ggtcctgcac cagcgcgggc tcgtccagct gcacccactc cgcaccggcg
     8761 gcccgcagtt cggcgagcac ctcggcgtac accggcagca gccggtcgag cagggtcagc
     8821 gggtcgaagt ccgcggccac cccgggcgcg ggcttggcca ggagcagata ggtgaccggg
     8881 ccgaccagca ccgggcgggg tcggtggccg agcgcgaggg cctcgcgcag ctcggtgacc
     8941 tgcttgccgg ggtcggcgcg gaaaacggtg ccggggccca gttcaggcac caggtagtgg
     9001 tagttggtgt cgaaccactt ggtcatctcc agcggcgcca cgtcctgcgt gccgcgcgcc
     9061 atggcgaagt agccgtcgag ggagcatccc gcgctcggcc gaggccggga gctgggagca
     9121 gggtccgcct cggcggcggc gcggtgacgt tcgggaacgc caccgaccat gacggtggtg
     9181 tccagcacgt ggtcgtagta cgagaagtcc ccggtcggca cctcatggat cccggcgtcg
     9241 gccaactgcc gccagttcgc ccgacgcagc tccgccgcgg tccggcgcag ctcatcggcg
     9301 gtgacccggc ccttccagta cccctcgacg gccttcttca gctcccgttc ccggccctgc
     9361 cgggggtagc cgtacacggt ggcccgaacg gtcgcggccg cggactgccc ggccccggtc
     9421 cctgtcgctg tctcggtcac aagaaactct ccttcgcgag cttgtctcct acagatcccg
     9481 gagacggaac gggggcgcga aggacgaacg aaccggacgg agcagctcag gagttcagca
     9541 acggcgagcc actgtccgat ctgtacgccg acccgccctc gaaggtcacc ggaatgtccg
     9601 cacgcgatcc ctcacgcgcg ggcaacgggc aggtcttcgg actcgcgggc acgtccaccg
     9661 atggaactct ggcaggcgga cacctactgg ccgtcgcttc ccagacccgt ccgggcccag
     9721 tgcgtatgac ggcgatcgtt cccactcacc gctgcggggc agtcccggaa tcccaccggg
     9781 ttccctctta cgacgcacct gtctggcgga cagggcgaac cagctgcccg accagcgtaa
     9841 cgcctcctcc gtggctagcg gcccgtcgcg gccggtcggt attcggtgag caggagggcg
     9901 atgtcgtcgg cgcggtagga ggagcgttgg gcgtgctgga ggaggcggtc ggcgagctcg
     9961 tccagggagc cggcgcgggc gtgggccagg gagctgcgga ggtggtcgat gcccacgtcg
    10021 atgggggtgc cgcgctcctc gaccaggccg tcggtgtaga gggcgagcac ggagccgggt
    10081 gggaggtcga cgggggtgcg cgggtagtcg cttgcgtggt ccacgccgag gagggggccg
    10141 gtttccaggt ccagtacgtc ggtgtgcccg tcgggatggc ggagcagggg cggtgggtgg
    10201 ccggcgcgga cggcccaggc gcggtggccg gccgggtcga ggtggaggta gcagcagctg
    10261 gcgaggaggc cggtaccgag gtcgatgagg gtgcggttgg cgcccgccag gacgtcgccc
    10321 ggggcgtgcc ccactgccac gaacgccctt accgcgctgc gcagttgggc catggtggcg
    10381 gcggccgcga tgctgtgtcc ctcgacgtct ccgatgacca gggccacgcc ctcggcggcc
    10441 gggatgacgt cgtaccagtc accgccgatg tccatgccgc tggtgcaggg gaggtagcgg
    10501 gccgtcgtgc gcaggtcggg gaggacgggc agccggtgcg gcagcagggc ctgctggagg
    10561 ccgcgggcga gggcgaattc ggagtcgtag agccgggcgc gttccagtgc ctgggcgatc
    10621 aggccggcga gcgcggtcag gacgctgcgg tccttggccg tgaagtggtg gatctcgtcg
    10681 aagccgagga cgcaggtgcc ggcggggcgg ccggaggcga tcagcgggag gtacgcccag
    10741 gagttcacgc cgccgatcgg gatgccgggg tagccctggg agaggctctg ctgtgactcg
    10801 atgaagagcg ggatgccgga ggtcagggtt tccgtgccgg gcaggggtgc gcgcagcggc
    10861 atgccgtcca gccagtcgag gaagccctcg tggtggccgg tgtggaagat caggtgcatc
    10921 gtgccgtcac ggaccgcgta gagggcgagt tgctggccgc cgaaggccgg gaggagctgg
    10981 tgggcgacga cttcgcagac ctggtgggtg gtgaccgcct cggtcagcgc actgcccagt
    11041 tgcaggacgt ggtacatgac gcccagtcgg gccggtgcgg cggccgcggt ggtggagggg
    11101 gccggagggg tcggcgccgc ggccgcagag gccggctgtg gcggtgcggt cacggtgggc
    11161 ggctcggcga ggtcaggggc ggcgtcgggg cgtccggtgg ggacgacgcg gccggtgacg
    11221 ccgttcgggt cggggtggag ggagaaggcg agccactggt cgggcgggcg gcggacgagg
    11281 aaggacgtcg gcgtctgcga gaccatcgcg gagcggtgct ggtactcgat cgcgggatcg
    11341 gacagccacg gcagggcgtc ccacaggcac tgcccgacca ggtcctcgcc cctgacatcc
    11401 agcaactgct ccaggctgcg gttggcgtag ctgacccggc cttcgggggt gagggagaac
    11461 agtccgtccc gcaggcgctc gaccgccgca gccgccgcgc ggccggcccg cgcgtcgacg
    11521 accactccga cgaggtgggc gcgcgcccgg tcgtcgtccg gcagatccgg cacccggccc
    11581 cagagcacca cgctgcggta cccctcgccg ctgccgtgtc cctcaccggc gccttccgcg
    11641 ccaccgcccg gcccggcgcc cgcgccctcg cgtacgcgca gggtccggga cacgatccgc
    11701 ccctcggcgg ccgccgtacg ggccgcggca cggaacgccg cgcggtcgcc ggggtggaga
    11761 cgggaggcca gggtctccgc ccgcgcgtcg aaggttccgg ggtcgaggcc gaagatcgcg
    11821 cagaagtcgt cgtccgcggt gagggtggag gcggacaggt tccagtcgaa caggccggcc
    11881 cgtacggccg gggcggaggg ggccggagtc tcgaccgggg ccgtgcgcgc atcgccctcc
    11941 agggggtcgc cgctgcggtc gcggcaggcc gccagggagg cgccgaggcg gttggccagg
    12001 gcccgaagat ggcgccgttg ggtcttggtc agcccgtcgc tgccgggcgg cgcggcccat
    12061 acgaccgcga gcgcaccgaa ggtctccccg cccgcgccca ccggtacgga gcaggagccg
    12121 aaggcgtacg gcagggccac cgcgagctgg ggaaagcggc gcatggtctc gtcggcgtcg
    12181 gccaggtgga tcgtgcgccc ggagccgtac gcgacggcga ccggtatcgg gctgctcacc
    12241 ggaacgaggc tccagccgcc cagctgggac ggcggtaccc cgcaggtcgc ggcgagcacc
    12301 agggagcggc ggtcgcggga gcgcaggaag atgcttccgg cgtaggcgcc cgccccctga
    12361 acggccttga cgacggctgc cgccagcagg tcgtcgcgct ccgccgtctc ctcgcgcacg
    12421 gtcgaccggc ccatgcctcc agtgtgcgca gaggcgggcc cggcggccca gaggattact
    12481 cagggcgatg gatgcgctac cgggcgcacg ctccgggccg ccggcgagcc gcgcccgtcc
    12541 ggttcccggc ggcgcgtcag ggccggaagg gcgcggaaga gctttccttg tcggccgccg
    12601 cctcgcgggc gttgtccagt tcccgccctc ggaacgtgaa gaacacgatc aggacgccgc
    12661 cgcagacgat ggcccagtcg gccaggttca tcacgctgaa accgcggacc gagatgaagt
    12721 cgaccaccgc gccctggagt tggccgggcg tccggaagag gcggtccgtc agattaccca
    12781 gtgcaccgcc cagcaggagg cccagggcga tcgcccacgg gacgctgtag agacggcgcg
    12841 ccaggcgaac gatcgccagg gcgacggcca cggcaatcac cgtgaacacg agggtgcttg
    12901 cgctgcccat gctgaaggcc gctccggaat tgcgcatcac ccgcagctgc agccaggtgc
    12961 ctatgacgtt caccgggtcg tggtgttcca gcttcgccac cacggccagt ttgctgaaca
    13021 ggtcgatcgc ataggccagg cacgccacca tcaggagcag cgggattcgt cgtgtgcccc
    13081 tggcttccct ccccccgcgc tcgctctcgc cacccgccgc gccccgcccc ggatccgtca
    13141 cgttcggtcc cctcgaagtc cgtatgtccc gcctcatgat cgcgcatgcc gtccgccggg
    13201 gcaggtcata cccccgcgag gagcggccac ggagccgtct ccgctccacc ctgtccacac
    13261 acctccggcc tgccttccgg agaaccgaaa gacaggccgg atccaagaga tcggagcggt
    13321 gcgaccggac ggtccgccgg gatcagaccg ccggcggcgc cgggtaggtc gggtactcca
    13381 ccccggagac gtgctggacg acgcggatga cctggcacga gtagccgaac tcgttgtcgt
    13441 accagaggta gaggatcgcg ttgtcgccgt cgaccttggt ggcgccggcg tccacgatcg
    13501 aggcgtggcg cgagccgacg aagtccatgg agacggcgtc gggggcggtg gtgaagtcga
    13561 tctggcgctt cagcggcgag tgcagggaga cgtcgcggag gtagtccagg acctcctcgc
    13621 ggctggtctc gcggccgagc cgcaggctga ggatcgcgat cgagacgtcc ggcaccggca
    13681 cccggatcga gctgccggtg atcggcgcct tgaggtcggg cagcgccttg gcgacggcgg
    13741 aggcggcgcc ggtctcggtg atgaccatgt tgagcggcgc ggagcggccc cggcggtcgg
    13801 ccttgtggta gttgtccagc aggttctggt cgttggtgaa cgagtggacg gtctccacgt
    13861 gaccgcgcag cacgccgtac tcgtcgtcca tcgccttcag cggcggcacg atcgcgttgg
    13921 tggtgcagga cgcgcaggac aggatctgct cgtccggctt gatcgtgtcg tggttgacgc
    13981 cgtgcacgat gttcgggacg tcgcccttgc ccggagcggt cagcacgacc ttctcgacgc
    14041 cggggcgcag gtgcttcgac aggccctcgc ggtcgcgcca cttgccggtg ttgtcgatga
    14101 ggatggcgtc cttgatgccg tgcgccgtgt agtcgacctc cgacgggtcg ttggcgtaga
    14161 tcaccttgat cgcgttgccg ttggcgatga tcgtgctgtt cgcctcgtca acggtgatcg
    14221 tgccctggaa ctggccgtgg atggagtccc ggcgcagcag cgaggcccgc ttcacgaggt
    14281 cctgctcgcc gcccccacgg acgacgatgg cgcgcagccg caggccgttg cccgagccgg
    14341 ccttctcgat gagcaggcgc gcgacgaggc ggccgatgcg gccgaacccg tacaggacga
    14401 cgtcacgggg tgcgcaacgc tcgatcttgt tggcaccggt ggcaccggcg acggcctcgg
    14461 cggtgaactc cgccaccgag agaccgcggt cgtcggcctt gtacgtcgcg gcgagcatgc
    14521 cgaggtcgat ctgggaaggg ccgagatcga gcgtggtgag ggcctgcagg aacggcatcg
    14581 tctcggtgac cgagagctcc tcacccgcga tctgccgggc gaatcggtgg gtcttgagga
    14641 tgctgaccac cgacttgttc accaaggagc ggctgtgaag caggaccgtg acgtcccgct
    14701 ccctctgcag cttcccgatg atcgggatca tcgactccgc gatctcctcg cggtttatcc
    14761 agttggtgaa cgagtcgtcg ttgacagtca caggattatc tttcgagcta ggcggtgctc
    14821 atatgctaac ccctcggctt tttgatcatc caagcggtcc cacctgaacg ggatcccgcc
    14881 atcaccctca tgactacgag gtgggcgaaa tgtcccgctt tgccacgcaa gtccgttgcc
    14941 ttttggggtg attagccccc tcggcgcggg gaccgaaaac gacgttgcgc cggcccccga
    15001 tgatcactaa ggtcagccgg gtgactgccg ggtcggccat gggccattcc accgtgaggc
    15061 tcccggcctc ggcgtgagtt cgaggcgggc aagagccccg cccctcctcc gtgtcttctc
    15121 gctccggcgc cccccacgcg gcgcccttcc cagcacttcc ccagacccgg agacacacca
    15181 cccatgccgt acgaccaaca gcacgcccac acctccgagc tgccgaccac cctcgcccgg
    15241 ctcaaccaca ccgccgtcta cgccagtgac cgccggctct cggccgagtt cctcgccgcg
    15301 atcctgggcc tcgcggtcag cgcgccgttc ggccccttcc tccccgtcga cctcggcaac
    15361 ggcgtcacgc tcgactactt cgagaagcgc gacgaaccga tccagccgca gcactacgcc
    15421 ttcctcgtgc cggacgcgca gttcgacgcc atgatcgccc gtctcgaagc ggtcggcgtc
    15481 acctacttcg ccgaccccca ccacaccgaa cccggccgga taaaccgcct gttcggcggc
    15541 cgcggcgcct acttcgccga ccccgacggc cacaacatgg agatcatgac ccggccctac
    15601 gcccgcccgt aggcgcgtcg ccacgcctgc cgtcccggat cagcacccgg gacggccggg
    15661 ccggtcctca gccgatgctg cggcccaagt aggcggccag gcggtcgaga gggctcgcgt
    15721 cctcgggggc cggctgcggc ggggcgaagg agcctgcgtc ggtgcgcggc agatcgccgt
    15781 agatctcctg gacgaccggg agggcgagct cggccaggtg ctggacgtcg tcgaaggggt
    15841 gcccgatggc ccgggccagg tcccagccgt ggagcagcat ctcgatcacg acttgctcga
    15901 cgagccgtcg cccgggtgcg gggccgtagc gctggtcgag catgcctggg cggccgaagg
    15961 cggaccgggt ggaccgggag gcgagacgga acgcctcgat gtggtcgtcc ccgaggtgat
    16021 cggcggtgaa gtcggagcgg ggagtgccgt tggccagagc ggtccagagc aggttctccc
    16081 ggaccaggtg gttgagcagg gtgcgtacgt cccagtcggc gcagggcgtc ggttggccga
    16141 actgggccgg gacgaccgcg gagaccaacc tgctgacggc gttgaggacg tcgtcgcagg
    16201 cctggagtac gcctgccggc ccccaggtgt cctgccccgc gtcggcgtcg tacatcgtgt
    16261 ggagttccgc ggctcgactg cctggtgtgg ggttggcccg cagtgcggtt ctcagccact
    16321 ggccggcggc ggccatgctc ggccgcgcgg ttccgccgtt gatgaggcac aacaggtgcc
    16381 agtaccgctc gacgtgcggg tcggaggcga cctccagctg ttccaggaga agccgtctgg
    16441 cccgggcgtc gtcgacgggc ccgaccgggt gcggatcgcc ggccggcgca gtctgtgtgg
    16501 gtatccatgc cgtcacgatg gcggcgacga cggggtcggc cgcgggtgag tcgggggcga
    16561 tcccctgctt cctcgccgtt tccacccgcc gcagccagtc atcggtgagc cgttccgccg
    16621 cctggagcgc ggccgggtcg tgttctcctg gccggtggtc ggcggcgtag cgggccatgc
    16681 ggcgcatacc ggcccgtaga gcggggtcct ggacgagtgc gcccagttcc agccaggcgt
    16741 cgacctgctc gtcgctgggg tcggccggga ggtcgggggt ggccgccagc aggcccctcc
    16801 ggtaagtggg gacgtccagc tcccccaggg tctcggtgac gaagtcctgg atgatggtgc
    16861 ggcgttcggc gtcggacatg cgcgccagct cggtcatggt ggtgagtccc tcggcagtgg
    16921 tgtcgcggcg gatgacggag cgcagcacgg cctgctgcga tcgcagcgtg cggatctgcg
    16981 cctccagcgc gtcgatgtgg gtcgcggcca cctgcgtcaa ggtgtcctcg cgctccagca
    17041 cgtcccggat ggtcgccagc cccaggccca gcccgcgcag ggtccgcgcc agttggaggc
    17101 gggccagggc ctcggtgccg tagagccggt agccgccggg cgtccggcgc gcgggaggca
    17161 cgatcccgag gtcggaccag tgcctgatca gcttcaccgt cagcccggtc ttccgggcga
    17221 cctctccgat gttccagaac gtgtcttcgc cgacgcgcat gccctccacc cttgggtctc
    17281 ccacggtggg agagtcaacc ggccggggtg gccggggcgg tgtcgtgtcc ctccagcaaa
    17341 cggttgcgga acaggtcgag tacgtcgtcc agtgctgccc gggtcggctg gcccggcgcg
    17401 tcgatgaggt gctcggtgag tacggagtgc gggcgcagca ccgcgtcggg gttcgcggcg
    17461 tcgtcgtcga gttcgacggc gacgaacgcg tcgccgagtt cgcggcggag gaaggcgaac
    17521 cggtcgcccg gcaccaggcg gtccgagcgg aagcgcagcc ccatgacctg aaggccgtca
    17581 cgtgcgcagc gggtgcggac ggcggcgagg tcttcgctgg agatgtcgat gccgccggcc
    17641 cggcccctgg tgacgggcaa gggcagcgaa ggctgggaca ggacgggggc cacgaggcgc
    17701 tcgtcgacgg ccatcgccag ggcgaaaccg ccggtgaggc acatgccgac ggcgccgacg
    17761 ccggggccgc cgcagcgctg gtgctcatgg gcggccaggg cccgtagcca ggtcaccacg
    17821 ggggaggact tcccggtggc gagcatggtg aattcgcggc tcacgcacac cttgcccagg
    17881 gaagaggcca cgtacgtggc ggacttgagc cggcggccgg ccgcgaagtc ggcagggcgg
    17941 ccgggcgtgc cgaagagcac cgggaggacg gcggtgcagc cgatggcggc cacccgttcc
    18001 gcgaagtcca gcaccttggg cgtgatcccc gggatttccg ccatcacgat caccgcggga
    18061 ccggtaccgc gacgcaggac ctcgcgggtg actccgtcgt gggtgaaggt gtcgcggtga
    18121 aaaccggtcg ggtgctgttc cgctgccatg gagtgcctca tcctgtcctg atcaagtcgg
    18181 cgtagtgcca caagagttgg atcaggatgc cggtcctgcg acgagagcgc agcggtgagg
    18241 atcacgtcgg cgccctctcg cctcatgtgg cgctctgtgg atggccggcc gttgccgagc
    18301 ggggtggcca ggactggggc gcgaggatgc cgaggacgta ggcgcgggcg accagggcgc
    18361 atcgggtggg ggcgttgagg atgtcgcgca ggcggctgag gtggtagtcg acggtttggc
    18421 gggagaggcg gagggaggtg gcgatctcgg cgttgctgcg gcccgcggcc aggagggaga
    18481 ggatgcgtac ctgactggcc gtcagcgcgg gatggggttc gtgggcgagg ctctggtggg
    18541 tgatcaccgc ccagacactg gcggcgcggg acgggccccg gcccacggtg gtcaggtgca
    18601 gttgggcgcg gcgctggcgg ccgcggccgt cgacgaggac ggcggaggtc tggatgcgcc
    18661 ggctgcggcg ggctatcagg gcgtgccagc ccttccggag tgcgggtaac tccggggcgg
    18721 gggcgagcag ggtgtgtgcc cggcggccca cgaggtcgga gagccgggtc tgcaggagtt
    18781 cggcggctgc cgcgctggcc tggaggatcc ttccgccggc ggagatcagg gcacacggca
    18841 gtccgctgtg gtcgcgcagc gcgtacaggt tctcctcggc ctgctggcgc tggtggaggg
    18901 cgcgggtgtg gtcgctgatg tcgatataga taccggccac gcaggtctgg gtgccctcgc
    18961 gtaccgggaa gcggtggccg gccgcgtggc cggtggcgcc gtccgcgcgg tggtaggtga
    19021 gggtgtgccg caccggtttg ccgcgggcca gcacctcctg gtccagggcg agcacccggt
    19081 cggcgtcggc cggggcgtcg acctcgcgta cgtccttgcc gatgacgtgc tccggggtcg
    19141 ttccgtagag gtgcgcgtag gcgtgattgg cccagaggta gcggccatcg gggtcacgga
    19201 tgaaggcggc ggcgggggcg agatcggcga aggcgtcgta gcggcgggcg gcggcgggaa
    19261 ggggaacggc gggagccggg gacggggccg ggtcgcgacc ctccccggac acctcgacgg
    19321 cgatgccgcg gaggcggtcc tgccggggcg ggtccagcgg ccagttcacg tcgaagagcc
    19381 ggccgtcgaa ccgtgcccgc cggtggttgc cggcgggcag gtggtcggct gcccgttcgt
    19441 gctcggtgac ctgcgacgca tcggtggcgt gcggctggtc gacggcctgc cattggtccg
    19501 tgacggtgtc gaggaagcgc tgggcggtgc gggtgtcgtc gaaggcccct cctccgctgt
    19561 cgatcacccg tagctcgcgg tcggcttccc accaggacac cgggaggtgt tggagcagcg
    19621 acttcagacc ggtctcgtcc acgacggcct ctctgtgacg aagagacgga gagatgggcg
    19681 gggcgttcgg ctacctcgcg tcccggccgg ctcgcgcgcc gggccccctc gcccttggca
    19741 tgcgtatccc ccgccgctac gccgtatgcc cggttctcgg ccgatctggt gggcgccggg
    19801 ctccatacgg catcacagaa ccttcacagc cgctcggcga actccacaac tctggcgttt
    19861 gcctgagcgt tcggcgccca tgacagcgaa tcgggcaccg ccgggctggt tctctggagg
    19921 taccgcgtcg aggcgtcagc cgccgcgtca tcaacggccg ttcccacggc cctccccgcc
    19981 tgtgaaggag acggattcca gtgagcacgg tgctgttcgt gtatgccaag ggcgggccgc
    20041 ccttggggta tgccctgtca cgggtcgccg ctcggtcggc agtgcacctg ctggcactca
    20101 gcacgcttcc gcccaccgtc gccgcctccg ccgagcgccg gtgcgcgtcc gtacggaccg
    20161 ccaccggccc cgagcggggc gacctggtgt ccctgatcgt ctcccgggcc caggccgtgg
    20221 gcgcggacgc ggtcatcacc ttctccgagt acgccgtcgt cgcggtcgcc gaggcctgcg
    20281 agaagctcgg cctggccggc gccggtgcct cctgtgcgct cgcccgtgac aagcggctga
    20341 tgcgccggac ctggggccgg cggggcatct cgcagccgcg gttccgcccg gtggccgacg
    20401 agcgggagct gcacgacgcg gccgccgagc tccgcctccc cctgctgctg aaggccgcct
    20461 ggagcgccgg ctccaccgcg caccggatca tccgttccgc cgaggaggta ccggccgcct
    20521 ggcagcgggc ccgcgaggtg atggccgaat ccgccgaact gggctacgcc gagctgcacg
    20581 tggccgacgc cggggccgac ttcctggtcg aggagatcgt gccgggcacc gcgggcggct
    20641 ggttcgacca gccgggctgg ggagactacg tcagcgtcga gggcgtcgtc gtcgacggcg
    20701 tgttccgacc ggtctgcctc agtggccgga tgccgacggt ggaaccgttc accgaacgcg
    20761 ccggcatcac cccggccgcg ctgccgaccg acgcccagca gcgcgtcgtg gccctcgccc
    20821 gcgaagccgt cgacgcgctg ggcctggaga actgcggtac gcacaccgag atcaagctcg
    20881 gtgccgacgg ccggatgtgg gtcatcgaga ccgcggcccg gttcggcggg gcgatgaccg
    20941 tcccgcagat cgaggaggtc ttcggcctgg acctcatcgg catgctcgtc gaccatctgc
    21001 tgggccgccc ggtgacctgg cccgcccggg ccctcacccc gcaggaggcg cgcggcgcgg
    21061 ccggctcctt cgtcgtattg gccgtggacg gcgccggtga cgcctggccg gaccgccgtc
    21121 ggtgggactt cccgaccgta cgggacgcgg tgccgctcag cgccggcagc cggctgtccg
    21181 tggtggccga aaactcgctc ccggacggat cgccggtccc ggtgtacgac ccggccgcgg
    21241 gcgccaacac catggccgcg ctgtgcctgt tgtccgccgc cgaccccgaa accgtgctcc
    21301 aggacttccg gaccctgatg gacgcactgc cgtcggtgct cccccaggcg gagagccaca
    21361 aggagacgga aacagacgcg gagacgaaga cggagacgaa gacggagacg aagacggaga
    21421 aagccgagaa ggacgagaag gacgggcagt gcaaggccga gaccgtggag gcacgctcat
    21481 gaccctcgcc atgaccatcg ccacgaccac cgcccccgac cccacggcag ttgacgacag
    21541 cacggcagtt gacggccact cgacagccga agaccgtacg gccatcggcg cgcagctggc
    21601 cctcccgctc ttccacaccc tctgcggcac cctggccggc cacccctacg tgaaggtcgt
    21661 ggtcgaccgc gtcgagaaca cctggcacct gctggacgcc gccgtccacc ccttccacgt
    21721 cgactacatc gccacccgtg tcctgggtat ggagctggcg gaactcgact cctgcctgga
    21781 cgcgttcaac gcctcggtct acgccgcccc ggagcgcagg ttcctgttgg gcgtgctctc
    21841 cctgcacacc gacatgggcg cggggacggc cggtgcgggc acccggattc ccaccggccg
    21901 ccgggcgcgt cccttcctcg tactggagac gaccgaggcc gacaccatga gcggcccgat
    21961 gctccaggag ttctacacgt tcgttcgcca ccggctcgac agccggctgc cgctgctgct
    22021 gaagcccgcg aaccacggtc aggaacacgc cctcaccgcg atcagcgacg tccgcgtgcc
    22081 gcggatcctc agccaccagc tgttcggcag ccgcacccgc accccgctca accccggcga
    22141 ggccgtcggc cggctgcgcc acttccgcac cgcccgggag tacgaggtct acgcggccgg
    22201 cgccggcacg ctcggcgggt ccgacatcgt cgccatgccg tgcctgcccg acgacgtacc
    22261 gagggtcgcc ggcttcatca acaccgcgcc caccacgcca ctctcgcaca ccaacgtcct
    22321 cgcatccggc tggggcatcc ccaacgccat catccgcgac ctggaccagc tgatggaggc
    22381 ggagggactc gcggacgcgg acgcatgggt ccgctacgag gtgcgggacg acgacatcgc
    22441 cctcgtacgg ctctcccagc caccggcccc gacgctcacc ccgtcgcctt ccccgtcgtc
    22501 tgcggcgggc gcccagacgt cgacgatgga tgcgtcggac ccacgcccct cgcacccgat
    22561 ccggctggaa cccccgctcc tgcacgccga catacccgcg ctgcccctgc gccaactgcg
    22621 ccgcaccgac cagaaccgct acggcaccaa ggcggccaac ctcggggaac tgcatcacgt
    22681 cctggccggc gacacggctg aacagcctgc acgggccgga ctgactggac cggctggacc
    22741 ggctggaccg gctggaccgg ctggtgaatc gtccagccgc tccgtcgacc tgaccgcgta
    22801 ctacggccgc cccaggccgc cccgcgccga tctctacgcc cacctcacca cccgcctggg
    22861 cctttccgga cgtcctggcc ttcctgacct tcccgagggc acgcggggcg cgcaactccg
    22921 cgccgccgca cgggacttcg tccgggccac ggtcaccgct cccgacggca tcgcccttcc
    22981 gttcgccctg cagcaccgct ttctcacctc ctcccccgcc atacagcagg ccatcagcga
    23041 gctgaaggcc gtcctggagc gcgaaacggc cgtcacggtc gacgtcatcg acccgctctg
    23101 tcggcgactt caggacctcg tccagcacac cgccccgatg cccgacgacg tggcccgtgc
    23161 catcaccgcc gccctccggg ggctgtcctc cggcccgtcc ggcgctgccg gtcggctcgt
    23221 ggtgcgctcg tcctccaacg ccgaagacct gcccgggttc tcggcagcgg gggtgtacga
    23281 ctcggtcacg gcggtgcacg gtgcggacga gctcgtcgcc gcggtacgtc aggtgtgggc
    23341 ttccctgctg tcgccgcgca gcgtccggct gcgccaccag gcgggcatct ctcccgacga
    23401 cacctacatg ggcgtgatca tccagcgcta tcagcccgcg gacctcggcg gcgtgctggt
    23461 gacctgcaac ccgacccggc gcgcggactt ccgcaacgtc tacctcaact gctcgcccgg
    23521 ttccccggag aacgtcgtcg acggcaccgc gctgccgctg cagtacctct acaacacggt
    23581 cgagggcggt ggccgcaccg tcgcgctggg ctcgtccgcc gaggacctgc cggccgccac
    23641 ccgcgaacga cttgcggacc tcgccctgac cggccggctg ctgcagtccc acttcagcgg
    23701 caccgccccc agccgtgtgg gctccggtga cgcgcacgtg gatgtgcacc ggaacgttgg
    23761 cgcggatgtg gacgtggacg tggaccagaa cgttggcgtg gacgtggaca tgggccagaa
    23821 cgttggcctg gacgtggaca tggccccgga cgtagaccgg ccgctggaca tcgaatggct
    23881 gatgaccgat cagggcgcct tccacctggt ccagatccgc ccctacgccc ggtgagcggc
    23941 catctccccg gctcccgggg cctccgtcgt gcgggcgggc gcgcgaagag ttcgacggac
    24001 gcgccgcccc tgccgccccg ggcccgccgc atcatccgcc tgaacaacgg cttccagctc
    24061 ctgttcaacc tgctctggtg gatgccggtg ttctacgcct accaacgaca ggcgggcctc
    24121 accgacggcc agatcttcgg catccagagc atctactaca ccgcgttctg cctcttcgag
    24181 atccccaccg gactggtcgc cgaccgcatc ggcacccgca actgcctgcg ggccggcgcg
    24241 gtcgtcatga ccgcggccaa cctcgccccg gtctgggccc ccagctacac cggcttcctc
    24301 gtccacttcc tgctcatcgc cgccggccgc tccctgacct ccggtgccgc cagtgcctac
    24361 ctctacgagg gtctgcgggc cgagggcgcg ggcgcccact acctgaaggc cgagggacag
    24421 gcccgcgcgc tcggcctcgc cgcgaaggtg ctgtgctggc cgctgctcgg tccgctgatg
    24481 gccatggcgc actccgcccc gtacgtcctg agcgcggcca gcgcgggcgg ttccctcgtc
    24541 tgcgccgtac tgctgccccg ccaggccgcg gccgtccccg ccgcgggccg gaagcgcgcc
    24601 acgagccacg aggcggccgc cgccctgcgc gccgtccgca gcacgccctg gctcgccctg
    24661 gtcatggtgc agggggtggc cctgttcacg ctctcccgta tctgccaggt caacctcttc
    24721 cagccggtac tgctcgacca cggcatcggc gagagctcgc acggcaccgt actggccgcc
    24781 atgaccgtcg cggaggcggt ggcctcggcc cgtccgcaat ggctcacctc gcggctctct
    24841 ccagtggcat gggtgtcgct gctcagcctc gcgatggcgg cggccctggc gggcagcacg
    24901 ctcggcggcc cctggacgac cgtcgcgctg ctgtgcgtgt tcgccgccgt gaccggtctg
    24961 gcgtctccgc tccagcggaa gctggtcaac gacgcggtac ccgcgggcgc gccccgggcc
    25021 accctgctgt cggtcgagag cctcgtcgac cgcgcggtgt gcgccctggc ggccgtcgct
    25081 gcgggcgcgt acctctcggc gcaccgcctg gacgccctgc tgtggcacag cgcactggcc
    25141 accgccgtcc tgctggcggt cctccacctg ctcctacgac gacatcatgg ccgggcccgt
    25201 acggcggaag gcggggcgca tagggagacc cgtgggatcc gtgcggagga cggcagggca
    25261 catacggaga gccgtggggt ccgtacggcg gaaggcggga cggagagccc tggggcccct
    25321 tcggcggaag gcggggtaca cacggagggc ggccgggcgg aaacgggccg taccgacgag
    25381 atccggccgg tcgccacagc aggaaagccc tgacccccgc gcccatactg gaggggtgcg
    25441 tactggaggg gtacggcggt cggacggacc ggccgaaccg gttgggcctc ctgggggtgc
    25501 tgggcctgct cgaccggctg gaccggccga accggctacc gggcactacg gcgaagaagc
    25561 cttccgtccc gaggaagccg gcgaggccga ccgcatcgac ctgggagcac tcgcctacga
    25621 cacggtgagc accgcacggc tgacggcgct gggcgccggc cccggctggc actgcctcga
    25681 cgtaggcgcc gggaccggca ccatcgcccg gtggctggtg gagtcggcgg acgtcacgtc
    25741 cgtcctggcc gtcgaccgtg acacccgctt cctcaccgcc gatgccccgc cggggctcgt
    25801 ggcccagacc gccgacgtca ccgcactcga cttcgacccc ggccgcttcc acctcgtcca
    25861 cgcccgcttc gtcctgatgc atctgcgccc gtggcgacgc atgatcaacc agctgagctc
    25921 actgctcgcc ccgggcggcg tactcgtgct cagcgacgcc gtcgacctga ccacctcctc
    25981 cgccccggcc accccgtaca cccgggtcat gcgcgcgatg tggcaggccc tgcgcaccac
    26041 gatcggtacg gacacctcct gggtgcccga ctacccctcc ttcctgctgg aggagggcct
    26101 gcactccgtt gccgccgaga tccacgttcc gccactactg cccggcagcc ccatcagccg
    26161 cttctgggag gacacttggc agcgcaccca cgacgccatc ctcgccaccg gccaggtgga
    26221 cgagccccaa ctcgaacagg cccgccggtc cctgtcctcc ccacactccg ccgccctctc
    26281 ccccggcatg ctcaccgcct ggggctggaa accccggcac accgcctccc cacccccgtg
    26341 atccggtggc aggcgaccgc acaccgttac accgttggcc cgttggatca ccggaacctt
    26401 ggcccgttgg atcacccgcc ccttggcccg ttggatcacc ggacgcttgg cacgttgccc
    26461 gtgagaagat ccgttccccc atcggccggt tcccggcagc cgaacgtgga aggtgtggaa
    26521 ggtaacgatg tacgcaatac ccctgggtga cgacggtgcc aacggcggca gccgcgccga
    26581 gctgcgtccg ctggagccgt ggcaggccga ggaattcctc gcccacatcg accgtggacg
    26641 ggagttcatc gggcagtaca tcgggctggc ggacctgatc gtggacctgg acgcgagccg
    26701 cgcgtacctc cactcgtacg tggagaaggc cgccgccgac accggccgcc tctgcggcat
    26761 ctggctggac ggccggctcg tcggcggggt cctcttccgc accatggacg tccatcaggg
    26821 cactgccgag gcgggctgct ggctggagcc gtcggccgcg ggcaaggggc tggtgacccg
    26881 agccgtacgc gtgctcatcg actgggccgt cgaggagcgg ggcatccacc gtgtggagtg
    26941 gctggtcgcg gcgggcaacg aacccagtat cgcggtggcc cggcgactgg gaatgaccaa
    27001 ggacggcgtg ctgcgcgaga gctatctgta ccggggccgg cgccacgaca tcgaagtctg
    27061 gtcggtactg gccccggagt ggcgcgcggc caagcgcggc gcctaggagc caggagccca
    27121 ggcggcccac tcatcccctc accgccctcg gcccctcacc ggtctcaccc ctcaccgggc
    27181 tcgcccctca ccgcgtacgg aaggagacca tcaggatgta cgtactggtg gccaacatcc
    27241 agaggggaaa gaccagttcg gtccaaggga cggaaccgac gacgaagagc agcacgagcg
    27301 cggccgcata gccgagccaa gcgagccagc gcgggaagac ccgcaaggcg agtccgatgg
    27361 tcgtggtgga cagcgtgaac accgcggcca tccgcatggc gtagctcgcc agcaaggtga
    27421 gcgtcgcccg cccgtaggtc cacaggtcct gcgcaccggc cgggacgttg ccggtgatgg
    27481 cgagcaggcc gccggcggcg gcccccgccg cgagcaccaa ggcggtgaac atcagcccgc
    27541 tgcacaggaa gagggtcgcg aagaacctgt tctccgcccg ctcttcctca gttcccgagc
    27601 cggcgttcgc cggacgcccg atgtcccgct ccgtgcgccc gatgtgatcc cgtacggcgc
    27661 ccatgaacca caggaagaag atgccggcga acggcaacag gcccagggcg acttccagga
    27721 tctgacggtg ggacgatcgt gacggccact cccccgcgcg ggccgggatc ggggagggca
    27781 agctgatgcg gatgatcatg agtacggcgg ccagcagcag cgcagccagc actccggccg
    27841 caccagccgc ccgcggcgta cgcagcgccc cgcccggcgt gacctccaga gagtctctct
    27901 cctccatcgc cccatcgtgg cgccacctcg cccccgaccg gctgcacagc cacccggcgt
    27961 ccctgacggc cactgagatg gcttacagcc tctgggcacc gaggcacggc acagcacttc
    28021 acctcacttc acctcccttc gcttcacctc accactacgc atcacaccac tctccaacct
    28081 tccctacttt cctcaaactt cctcattgca ctgacgaata gaggaggtta aggtactttc
    28141 atgcctgatc gtttctactc cgtggagcaa gtagcggagc acctgggcct gcatgtccgc
    28201 accatccgga actacgtgcg ggacggacgt ctgcacgcgg tgcgcatcgg caagcagtac
    28261 cgcatcgccc acgaggacct ggaagccttc accggccgcc cggcacccgc acctccgggc
    28321 gacgcggacg aacggcgacc gcaccaacag aagcaacaga agcaacagca caccgaggtc
    28381 tgcagcatcg tcgagatcga cgcgatcacc cccgagaggg tcgaccgcct gaccaacctc
    28441 ctgatgagcg tggccaccga ccgcggtccg ggccatgcgc ccctgcggat cgagacggcc
    28501 cacgacaagg agagggcccg gctgaaggtc atcgtcctgg gcggtctcgc cgacacggcc
    28561 cgggtgctcg aatgcatgga cggagtgctc gcgacatgag cacgaggacg aacacacgag
    28621 gacaaacagg agcatgagcg cgagcaccaa cgcccccacc agcaccagca cgatctacaa
    28681 gaccgaagcc ggtgcgaggg agatccagca gcgttaccgg gagatgctcc aagactggcc
    28741 ggtccccgcc gaggaggtac ggataccgac ccgcgaaggc gagaccttcg tcctcgcctc
    28801 cggcccgaag gacgcgccgc ccgtactact gctccacgga tcgggagcga acacgacgat
    28861 gtggctggac gacatcgcct cgtggtcgca gcacttccgg acgtacgccc tggacctcat
    28921 aggcgaaccg ggcttgagcg ccccctcccg cccgcccttg tcctccgacg cccatgcgct
    28981 ctggctggac gaggtgttgg agtatctggg cgtgagccga acggcgatcg tcgccacttc
    29041 cctgggcgga tgggtggcac tcgactacgc cacccgccgg ccggaccgag tgacccgtct
    29101 ggccctgctc tgccccggcg gcgtgggccg gcagaaggtg gcctggctgt tcaaggccgt
    29161 gctcctgcgc gcggtcggac gccggggggt gcgccggtca accgcggccg tcaccggcct
    29221 gagcgccccc gagacccagc atctcctcga tcacgtcatg ctgaccttca ctcacttcaa
    29281 gccccgcacc gagcggctcc ccctcttccc cgacagtgcg ctgcgccgcc tgaccatgcc
    29341 cacgctggtg acggtcggca gccgcgacgc catgttcgac tccgagggca ccgtccggcg
    29401 cgtacgccag tgcctccccc acgcgaccgt gaacgtcctc cccgaggccg gtcacgccct
    29461 cctcaaccag accgactcgg tcctcacgtt cctccgcggc tgaccggctt tccgaaatag
    29521 caccgcgccc atcccggcgc aaccatcaca cgacaccgga cggacggtgg actgtggtga
    29581 ccggcaccat gacgcgccgt agtggccttt tcgtacggtg accagcaatc cagcggtgtc
    29641 cccgcacgca gacctgtggc cgggcacctt cacaccggcc tgcgcccgcg cgcagacacg
    29701 gcacaccgct gggtcgcggg cccgaccggt ccctacggtc cgaccggctc gtaccgtcgc
    29761 cacatcgcca catcgccaca tcgtcacgtc gccacatcgt catgtctcca cgtcgtcacg
    29821 tcgccacagg aggtcacggt gacgctcccc ccaccgcaca caccgtccca ccagcagact
    29881 cccgcgtccc caaccgctcc agcacagcgc cgccgcccac gcgcacgcct gacccggctg
    29941 gccgccacct gcctgatagc cgcgggcacc gcagcgttac tcacccccac gcccgccgca
    30001 ggaatcaaca accaccacac caacaccgcc gcgacggaac ggccgaccac caccctggag
    30061 aagatcgcca acttcggcgc caacccgggc aacctcacca tgtacgtcta ccgaccgccc
    30121 caactcccgt tacatcccgc cgtggttgtc gccttgcacg gctgcaccca gagcgcccgg
    30181 atctacgccg acaattccgg gctgacgacc ttcgccgacc ggtacggctt cctcctggtc
    30241 ttcgccgaga cgacctccgc gaacaacccc ggccagtgct tcaactggtt ccaacccctc
    30301 gacaaccagc gcggccaggg agaagccgcc tcgatccggc agatggtcgc gtacgccaat
    30361 accgcctacg gcacagaccg ctcacgcacc tacgtcaccg gcctgtcggc gggcggcgcc
    30421 atgacctcgg tgatgctggc cacctacccc gacgtcttca cggcgggcgc cgtcgtcgcc
    30481 ggcctcccct acaactgcac caaggacacc gggccgttca cctgcatgaa ccccggcgtc
    30541 gacggtacgc ccgccgcctg ggcacaacgc gtccgcgacg cctacccgtc gtattccggc
    30601 ccctggcccc gcgtggcgat ctggcacggt gacaacgaca ccacggtcgc cccgaggaac
    30661 gccgacgaac tacgcgacca atggaccgcc gtccacggcc tgagccaaac cccggaccgc
    30721 acctccacca tcggcccgaa cgccacccgc agtcaggaat acctggccac ggacggcacc
    30781 gtagccgtcc aggtcaacaa ggtgccgggc atcggccacg gcactccggt cgacccgggc
    30841 acgggccccc aacagtgcgg ccggaccgga accgcgaact tcatcgcctc catctgctcc
    30901 agctactgga tcaccaaatt cttcaacctc ggttcctagc agggcggttc tctcgactgc
    30961 cgggcgcgca cgtgtccgtc gacagaactg cccactctcc tcctgggacc ggcgcgtccc
    31021 ggggcgcggg tggcaccgat ggaggcgagg gccacggcga ggacaccggc ccattggggg
    31081 acggccaggt gctggccgag caggacgagg ccgatgaggg cgccgacggc gggttcgagg
    31141 ctggtgagga cgccgaaggt gcggggcggc agccggcgga gggcctcgag gtggaaggtg
    31201 tagggcagaa cgctggagag gatggcgacg acggcggcca gggcgagggt ggtgggctca
    31261 agaagtctgg agcccgcctg ggcgatgccg tacgggaggc tgaggagggc gccccaggtg
    31321 acggcgaggg ccagaccacg cccgtccggg acgcgttccg cgagcctctt gccgaccagg
    31381 atgtagccgc cccagcagca tccggcgagg agggcacagg ccagtcccgc ggtgtcgagc
    31441 ggaatgccgg agtggctgag cagcacgaca cccgccgcgg ccaggcaggc ccacagcaga
    31501 tcggcggccc ggcgcgagcc gaacagcgcg atggcgaacg ggccgaggaa ctccatcgtg
    31561 gtggcggcgc ccaaggggag acggtcgacc gcttcgtaat agctgaggtg atggacggcg
    31621 agcagggtgc cggcggcggc cgcgacgccg agggtggtcc ggtcccagcg cagcccgggg
    31681 cgccacaggg cggtgaggac gacggcggcc aggcacaggc gcaggctgac cactcccgcc
    31741 ggacccacga cggggtagag ccgggtggtc agcgcggccc cgcactgcag accgagcacg
    31801 ccacccatga ccagaccggg ggcgggcact gcgcccaatc cccggctgat cacggcaatg
    31861 gcttgcgcac ggcgactgac gagctgactg atggcaccct ccgtccctcc gcccgtccgc
    31921 ccggtggcgt ctggccggac ggggaatcgc atcgcccggt cgcaccgacc tgcaacatgg
    31981 cacagcgaaa atggcatggc gacaacatgg ccacaacccc cgacgatcaa cgaaatccgc
    32041 atcactccgg gcccgttgac ctggcgaatc ggcagccgcg ccgcacatgg cagctgcgtc
    32101 cacctgtcag gtttccgtgg gaggaggagg acagccgcat caggtctttg cggggacttt
    32161 gcaggaccca tggagtccgc cccgtccggc ccgtgggccc cgtccggccc gtgggccccg
    32221 tccgcccagt gcgctcggtg cgccccgtgc gccccgtgcg ccccgtgcgc caggcagctc
    32281 agccgcaaag acgaggacgg ccgtcaagtg tcgccgcatc cactccggcc tcactgagca
    32341 ccccggcggc cacgccacga ccgatctggg cgagccccag aagcaggtgg tcgcagtcga
    32401 tacctgccga acccgccgcc tcggcccgct cctccgcgat cgcgatggcc ttacgggagt
    32461 agggcgtcca ggcaatccgc tccgccgctt gcgacgcccc catgctcagc cgcgccccga
    32521 cggccttgtg caggtcctcg ggcgatacgt cggcggcccg cagcagacgc gttgccgtgt
    32581 tgtcctccgc ggtgaggccc cagagcaggt gttccgtccc gatgtagttg ttgcggtgat
    32641 gcaccgcggc ctgcttcaca tgcaccatgg cctggcggag gtcgtccgtc atggtctcgg
    32701 gcccgtagcg cttgtggggt gcttgaaagc gctgctgcac ggcttgcctg gtcacgccca
    32761 gcgccgtacc gatgtccgtc cacgagctgc cgtgcatccg gcagtgctcg acatagtcct
    32821 cgaccaagtc gtctgccagt gcttgcagtt gaccggcaag gttcgccgcc accgtgagca
    32881 gtgcgagcca gtccggctgt tcttgtccac cgggccggtg cgcggcatcg caggtcctgt
    32941 cgacttccgc tatcaggtcg tccaagtctg ggagaggcat gaggcaagta cgcattgaca
    33001 attcccgttt gtcaaggcgc acttgccttc ctgtcccccc aacgtcacgt acgctgccgg
    33061 atatccagca cgcaccccac ctcccacctc ccacctccca tcccccacct cctcccatcc
    33121 gctccgaacg gcccggcaca gtgatcacaa acgaaccccc gcacctcccg tcgcccgacg
    33181 ttctctggtc ccacgccgcc accctcgccg cctggagtag cgagcaacag ctccccgttc
    33241 acaactaccg ccttgacgag accggactgc gctccgcgga cgtggggaac ggttggtggg
    33301 ccctgtcctg ggtcgagggc ggacgagccg tgctctacgg catcgaccac gactacagcg
    33361 acaccgtcgg cctggccccg cccgtcgacc tgctggccga cggaccctcc tggctgccat
    33421 ggcagtggct cgacgacgtc atcaccggcg gcgaggagat cggttttgtg tactggtggg
    33481 acggccggga gtgggcgcgg gctccgcacc ccgtcgaggt gcacgacgac ggcgtgcaca
    33541 gcatggtccc ggcggacgac agcgaggtgc ggcaggtctg cgatgccctg gtgaccgacg
    33601 gcgcggaccc ggccgccgta cgcgagcgcg aggcggcaca ccgacgaacc gctgccgccc
    33661 cggtcccgaa cggggccgcc gtgttgccgg ccggccaggg cgagcccacc gaccggaggg
    33721 tcccgtgctg gctgcctgag cagcacgccg cggtactcgc cgtggagatg agggcagcca
    33781 ccgaactcaa ccgcccggca ccgccggcca cgccggaacg ggaccgactg atcgcctggc
    33841 tacgcgccaa cggcccccgg acggagggga gttcggcgct ctcggcaacg ttcgtggacg
    33901 ccgaggacac cgattacggc cgcggcgcgg acggattcct ggacgtgctg ggccgacgca
    33961 tcttcggcga ggcagccacg ctgctggccg ccctgcggaa cgcggaagcc gaccccgaac
    34021 ggggccgctg gctatacatc cgcataacag tgaccaactc cgacaccgac tctgacatcg
    34081 acaccggcac cggcacgaac accacgagca ccatcgagcg cggctacgac tgcctgccgg
    34141 actggtggcc ggccagacgt ggaatcgtcg ccaccctccc ccacaccgtc cgcctcgaaa
    34201 tggcacgccg agcggcccac tggcgcccga actgggccag cctcctcgac gaagacatcc
    34261 gccgcgacgg caccccggcc cggctttgcc gggtggaact ggcaccaccc cacatctcgg
    34321 ctgcgaacgc gcacgcggat gcgcatatga atgcggccgc ggatgcggag ccaggttcgt
    34381 agggagttgg cactgccgtg gtgcgctggc cgggagcccc ggaggatgtg gagcgcggac
    34441 accacgtcga gtggaccgtc gaggaggaca tcgcctgggc cggcaacacc cgaccgactg
    34501 ccgacaccac gcccgcactg cacgaggacg gcgaccagat cgtcctccga ggccgactga
    34561 acctcaccgg agacggagcg gccttcctgg acctgggcag cggtacccag atcctcttcg
    34621 acctcgccga cccacctcct ccggacgaag tccatgggac atgggtcgag atccgcgtca
    34681 ggcgggagag cgtcagcctg tggccctacc tcgtctgaag tggccagagg ggtctctgct
    34741 ggtgggcggc ggtggtgggc ggcggggctc tgtcgtatcg acgacgggcc ccggtggagg
    34801 tgagacgccc ccgccgtggt ggtcaccggt caacttctgc agagtgctcg cgcttcgtcc
    34861 gcggagggcg tggtgcgtgc cggcgatcac ggcctgacct cctcaggctc gggctcgagc
    34921 tcccaggtct gctgcttgag cgccatgcgg gcggcgggcg cccggccggg gatgctcgcc
    34981 cagtacgggt gcgtggcgat ccgcaccgac agctgctgca gtctgcggcg cagcaccgtg
    35041 gtctgggatg ggttttcctc gcacgaaagc tctcggtacg cggtgtacca ggcgcgctga
    35101 gcctgcacga gatcttcggg gaaggcatag ggaggagtca cacgaagatt gcatcacatg
    35161 ttcgaattgc ggtgcagcac acgtacgagt gaatccggcc ctctccctca ttgagccggt
    35221 gggccgccac ccgacgccta cgtggcagcc gaggcagccg accgctgagc gcgcgcccgg
    35281 gcctggtccg ggtaccacct cgtgaagcgg accgcgccca cgagcaacgc gatcggaatg
    35341 atccagttga gccagtccgc ccctgacgtg gtgtgcaggg cgaggacgcc aagcagggcc
    35401 gtcaccagga acaccgctcc ccacaccgcc gtcagtaccc ggttgacgtg ccggaagagc
    35461 gggctccccc agtacgcgcg gggcacggac tcccgggcgt actgctcggt gaacggcatg
    35521 aaggcgaggg aggtgagggc cacaacggcc agcaccccgg cggacagggt ctgggcgtat
    35581 gtctccagcc agatcagggc gtggcggtcg aggaccagcg acagggtgca gatgacggcg
    35641 aagaaaagca tgccggcgat gtccaggatc ttcaggctgc gccgcctgat gtcggggatg
    35701 ctggccccga tcgccgtgat gagcgcggcg agtgcggcaa acccccacga actggggctc
    35761 gccaccacgg cgaaaatgat ccaaggggcg aagccgagga agaggttgag accgcgtgtg
    35821 gcgtcggggc gtcgcgggtc gctcggtgac ggcgcgtcgt cgggcttggg cgtcgtgtca
    35881 gggtgggtca tacgaaacct ccggtcggct ccgtccggtc cggcatccct gctgccatgc
    35941 tgtgctccac ggaccggagt cgcatccggt gcgcacctcg actcggcgaa cccgccacta
    36001 cggcgagtgg ccgttgctcg acgacgagca acaccccgag caaggattcg acgacgagat
    36061 ccccgagccg gtcgacgagg agcctccata cccacgccgg ggctcactga tgttgagttc
    36121 cgctctctgc atggtgagtt ccgctccctg ccagtcgttc agcgttcgac cttcggcgct
    36181 ttaagatcac ggacgatcgc cgtgcatcaa gccgttcgga tcggcgtttc agggagcgga
    36241 agcggagggg gaccgagggg gaccgatggc atacgagata gacctgccgc tggacgaaca
    36301 aggcgggaag ggcggagaac gcagagaaga cgctgcaggt gaagtaggcc gagcagcagg
    36361 tgaagtagac cgagcagaca acgaggccgc cgggctcgcc gcggaactca ccgaactcgg
    36421 caacgatggc ttcctacggg cgacgctccg cgaccagcca ccggcacact ttcaccaccg
    36481 cagcaccgac cacctcctag gctggccctc cggcgccccg gacatcgccg aacccacctc
    36541 cagcctcctg ctccgcgccc tgcacacctg cttcaccgcg cacctccccc tgagcctctc
    36601 gcccgatgtc ctctggtacg ccgtcgtgca cgaggtagcc gtacacatcc ggctgaaccc
    36661 cgaaacgtac gagggcatct tcacggagac gcccggacac cggcagacca tcgtcgtacg
    36721 ggacgattcg gccccgctgg actgggagcg ctcgatcaac ctcgtccaac agccactgcg
    36781 cgcccggatc ggtgacgagg tcgccgacct cttccagccc accttctcca ccaccacgga
    36841 cacggacgcc acggccatgc tggtggcgct gatggacgtg gtcagcccgt actaccgctt
    36901 tcggtggcag accctctgcg gcattccgcg aatccggttg gagggcacgg accgggactg
    36961 gcgtctgctg gcggcccggg tgcgggaact ggcggagtgg ttcgaagggc tgcggccgtg
    37021 gttcacggca ctgcagccgg tactggacgc gatctgggcg acggcctcgg gttggggtgt
    37081 cgacctcgac ttctggcgtt ccctctacaa gtgggagtcg gcctcgggcg gcgaccgggt
    37141 cacgggctgg atcaccgcgt tcttcgccca ccggtacacc gacgacggtc cgcgcccgaa
    37201 gccgtcgttc gggcccggca cgaccgccga ggacgacttt ccctcgcacg tctcccaggt
    37261 cccgttccgt tgggagaccc ccacgggaac gttggacatg gcgttcctcg gaggcatcct
    37321 cggtatcgag cgcgagggag agtggatccg accccaactc ggccacgtag tagccgagtt
    37381 ggctcccaca accaagccca gccccaacgc caagcctgcc accgagccgg acggcgcacc
    37441 gcatgccgaa ccggacggcg aacgagcgga cagaccgtac gccgacgcgc gcctgcccga
    37501 gccctggaca tgggcggacg tccagcgcct caccggctgc ccgcaggccc atccgctcac
    37561 caccatcggc accgtcaccc acaacggcag ccccctccag gtcgactacg cgatcaacct
    37621 caacggcatc tgcgcggtcc gggccggcga ccggaatgac gacggcgacg gcaactggta
    37681 tctgggcgat gtcgtctccg acgccgggga catccagtgc tgggcctcct acggcccgga
    37741 cctcggcgac gccttgcgcg cgctctaaca gccggccagg gtcaacggaa gtcggcagcg
    37801 tggtcaacgg cccactggtg caaggtccgt gccggccctc cggccacctc ctcgaccgtg
    37861 gtggtcgtga ccggccgcgg ggcatcaagc atctcggcgt acccgtccag cagggtgtcc
    37921 acgaaggagt cggggaaggt gtcgtcggcc agcagctgct ggcgggcggc ctcccgcgac
    37981 agttcctccc accggagagg ccgtccgatg gcctctccga tgatgcgcac ctgatcgacc
    38041 tgggtcagga tctcgggccc ggtcagcgtg tagaccgcct tgtcgtggcc ctcctcggtc
    38101 aaggcgcgta cggcgacggc ggcgatgtcg gcctcgtgca gcagagccat gggcaccgcc
    38161 ccgtaggcgc cgcgcaccac gtcgccggtg cggatctggt cggcccacca gagggtgttg
    38221 ctggcgaagg tgctgggacg tagatgcgtc cagccgagtc ccgaccgttc gatgaggcgc
    38281 tccaccgcgg cgtgggagcg gcctaccggg tgccgctgtt gcccgggggc gagcccgtcc
    38341 tggacggccc ccgaggagag aaagaccacg tgctccacgt gccgccgtag cgcatcgacg
    38401 acagcgggcg cggcgtcagc cgtatgaaag ggccacatga ggaaggcccg gtcgacgccc
    38461 tccagggcct cttccaggcc gcgggcgtcg gccaggtcgc cggcccgtac ctcgacgccg
    38521 ccgtacgcca ggccggccga gtccgggtgc cgggtcaggg cccgtacatg tacacctaca
    38581 cctacatcag tcgccaacaa ctgggtgacg acctggcggc ccacgtttcc cgtcgcgcca
    38641 ataaccagca cggtgcgctc cgccgcgccc tccgccgcac ggttcatggc cgcacccgtg
    38701 tccatcgcgg tatccctgtc catcgcgctt ctccctctgc aggcggcgtc tgtcccgctt
    38761 gtcaccgccc acagtgcgca acggagcgcc ggggccaacc accaatgcgg ggatgttggc
    38821 ggataccagc atgtcgagga cgatgacgac ggataccgtc atgacaggcg gagacaggcc
    38881 aggaccggtg gagccgggtc aggaccggtg gagccgggtc aggaggcgca ccggcacccg
    38941 cgccaggcgc aggcgaggac ccaaccgcca cccgatcccc gcccccgccc ccgcctcacc
    39001 tcacctcacc gcctacaaca ccgggtccga cgtcccccgt tgctgcggta tcgccacgcc
    39061 ctccggctgc tgtagtgcca ccgtccgtgt cggcgcggga atcctgattc cctcgtcccg
    39121 gtaccgctga tgcagccgct tgatgaattc atgcttgatc cgatactggt cgctgaattc
    39181 acccactccc agaatcaccg taaggccgat ccgagagtcc ccgaaggtgt ggaaacgaac
    39241 ggccggttcg tgttccggaa cggcgccact gacgtcggtc atcacgctct tgacgacctc
    39301 cagggtgacc cgctcgacgt gttcgaggtc actgtcgtaa ccgaccccaa cctggacgag
    39361 gatcgacaac tgctgttccg gccgggtgaa gttggtcatg ttggtgccgg ccagctgcgc
    39421 attcgggatg atcacgagat tgttggagag ctggcggacc acggtgttac gccagttgat
    39481 gtcgacgacg tatccctcct ccccactgct gagccgaatg tagtcaccgg gctgcacggt
    39541 cttcgaagcc aatacgtgta cgcccgcgaa gaggttggcg agggtgtcct gcaatgccag
    39601 ggcgaccgcc aagccgccca cgccgagcgc cgtgagcaga ggggctatgg aaatgcccag
    39661 ggtctgcagg atgaccagaa cgcccattgc cagcaccacg atgcgggtga tgttggcgaa
    39721 aatggtggcc gatccggcca cgccggatcg tgactgggcc agcgacctca cgagtcgggt
    39781 gatcatccgg gccgcggtca gtgtgacgac caggatgagc agcacggtca gcgtgcggtt
    39841 gacgttccgt ccgaccgtag gcgtcagcgg cagcgcagcg gccgcagccg ccagaccacc
    39901 ggatatcgcc gcccagggca ccacggatcg cagtgaatcg acaatgacgt cgtcgccgct
    39961 ccatcgcgtt ctgctcgcgt gctttcccag ccaccgcaac accgctttgc acaacagtcc
    40021 ggcgacgata ccggcaatca gcgcggcacc ggcaacgatc aggtcatgca gcgtgacatc
    40081 acggttcacc ggtcaacccc cgctcccggg aactgcagcc ctgccactgc cacgcatcgc
    40141 atgtgatgct ccatcattcg gttttacctg cttgtctcta ggacttcgaa tgcgccgggg
    40201 cccgaccgca gacgtgtgcg tgtacgtgta cgtgtccatg tacgtagacg aagacgtgaa
    40261 ggtcccgcaa gtcgtggtcg tcctgacgcg atcagccatc ctgccgcacg cgacgcgata
    40321 cgcagcgagc accccaggag aaaccaacca cccctgcccg cccgcctcca tcaggcatgc
    40381 gctcactacg aaccccaccc cacactccgc gccccgatct ggcccattct gccgtcaccc
    40441 acacgtgcgg tgctgcgcat ggacgattcc gcgaagggga gtcatgcgaa gccgcacgcg
    40501 tcgaccgata cacggcggcg gaccaactgg tgttttgaga agggccgact tgagccgtga
    40561 gaacgaacaa cgacaccaag tcgggtcagc gtcctgagga agggtgttcc atgcgccgct
    40621 ttgccgccct catgctcggt gccgccgcat tctgcggagc ggtcaccgcc gcgcctggtc
    40681 aggccatcgc cctggccaaa gaaccatgtg gcttctacaa gacaggcagt gatgcgtact
    40741 accgccactg caccacggac ggttcgaacg tcgtgatcaa ggtggaggtc gcctgggccc
    40801 ccgactacca gcgctgcgtc ggcccgggcc gtacgtggct gggctccgcc tccaggatcc
    40861 agggcgcgca ctacgtcggg cgcacctgct gaccggccac gagctgtccc tcctgctccg
    40921 gcccgttgcg acgactcgtc cgccagccgt caggccggca accggcagcc gtcagcctgg
    40981 caaccgacag ccgtcgcagc acacgggaat tacggagcct cgggcgactc agaagggaac
    41041 ggccacccca gcctctctca ttcgactcag ggcacggccc atacactcgg cgaccgaggc
    41101 gccgtcagct ctcatcggcg gcaacggccc gccaccggcg gcgaaggtcc acgctggccg
    41161 gccttcgcgc aggcgctccg catcgatgcg aatcatggct ccaatcccct gctcaccgag
    41221 ccactccagg atgagcagcg tcgcatcctc gacgccgctg tccagatcta ccgtgggcca
    41281 ccgccccatc cccttgccca tggccgcaac cctactgggc cggtcgggac tacgacgtgg
    41341 gtgcgctcgg gcgaggaggc agcccaacag gcatggggcg taggcggata ggcagggggc
    41401 gtgggcgtaa gcgcaagcgg caagcggtaa gcagcaaacg gcaagtggca agtggcaagt
    41461 gacgttgtcc agattgcgca gg
//
