LOCUS       NZ_AP026073            13142 bp    DNA     linear   CON 31-DEC-2024
DEFINITION  Streptomyces nigrescens strain HEK616 chromosome.
ACCESSION   NZ_AP026073
VERSION     NZ_AP026073.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces nigrescens
  ORGANISM  Streptomyces nigrescens
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Asamizu,S. and Onaka,H.
  TITLE     Complete genome sequence of Streptomyces nigrescens HEK616
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8253039)
  AUTHORS   Asamizu,S. and Onaka,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2022) Contact:Shumpei Asamizu The University of
            Tokyo, Graduate School of Agricultural and Life Sciences; Yayoi
            1-1-1, Bunkyo, Tokyo 113-8657, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: HGAP4 v. 4.0; Falcon v. 0.3; Canu v. 0.7; Arrow
            v. 2.3.3; Pilon v. 1.22
            Genome Coverage                   :: 262x
            Sequencing Technology             :: illumina Hiseq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024349765.1-RS_2024_12_31
            Annotation Date                   :: 12/31/2024 04:23:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,326
            CDSs (total)                      :: 8,236
            Genes (coding)                    :: 8,032
            CDSs (with protein)               :: 8,032
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 204
            CDSs (without protein)            :: 204
            Pseudo Genes (ambiguous residues) :: 0 of 204
            Pseudo Genes (frameshifted)       :: 84 of 204
            Pseudo Genes (incomplete)         :: 166 of 204
            Pseudo Genes (internal stop)      :: 16 of 204
            Pseudo Genes (multiple problems)  :: 56 of 204
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:47:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3168410
            Orig. end                         :: 3181552
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP026073.1.
            Annotated by DFAST https://dfast.ddbj.nig.ac.jp/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..13142
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="8"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..13142
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13142
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8142](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8142
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     misc_feature    98..112
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            complement(594..1547)
                     /locus_tag="HEK616_RS13800"
                     /old_locus_tag="HEK616_28040"
     CDS             complement(594..1547)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018565785.1"
                     /locus_tag="HEK616_RS13800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_28040"
                     /product="ABC transporter permease"
                     /protein_id="WP_261953234.1"
                     /transl_table=11
                     /translation="MSSPAPEPLAPEAAPLSTASGRPGQLVRRELRRRGSVKISLVIIG
                     LFLVMAAAAPLLSALGGWSPDAFDKSAVDPYLGGTPLGPLGGISADHWLGVEPVTGRDL
                     FARVVHGAQVSLLIALTATAIVVVTGTAAGIAAGYFGGRTDALLSRLMDLTMSFPSLIF
                     MIAMMSVAKDVNRILLMTAVIGLFGWPGVARVVRGQTLSLKHREYVDAARVGGSGPWRI
                     LTRDVLPGVAGPVIAYTTLIIPGMIATEAALSYLGVGVRPPTPSWGQMIAESVSFYDTD
                     PMYFVIPSACLFLTVLAFTLLGDALRDVLDPRGSRA"
     gene            complement(1565..3310)
                     /locus_tag="HEK616_RS13805"
                     /old_locus_tag="HEK616_28050"
     CDS             complement(1565..3310)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378669.1"
                     /locus_tag="HEK616_RS13805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_28050"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_261953235.1"
                     /transl_table=11
                     /translation="MNKRTRTAAACLAAALALGATGCAGGKDSADGRGRGTNPALVNQG
                     KVVGGTPKRGGTLTVLSNQDFTHLDPARNWVMNDMDFGTRLLYRTLVTYRAAPGPAGGT
                     LVPDLATDLGTPSHGARTWTFHLKKGVRYEDGTPVTARDIKYNVERSFSPDLPGGADYA
                     ARYLAGAEGYKGPADGEHLASVKTPDDHTLVFELRKPFAEFPDVTVMPTFAPVPQARDD
                     GPRYDNRPFSSGPYKIESYGRDKRLVLVRNPYWDPKTDPVRKAYPDRLVVEMGLKANQI
                     DDRLIAGQGPDASAVPWSALRPESAAKVLPHADVRARLLAESTNCTDMVQMHTGRAPFT
                     DVRVRRAVQYALDRDSVLTASGGPAFNDLSTAYMPASLFGGKQPDTLKIPTTGDVAKAK
                     QLLKEAGKPDGFSTEITVSSGDKGRAEAIQQSLAKAGIKVAINTVDPSAFYATIGDTKN
                     RTDLVFTGWCPDYPSGSTFLPFVFDGRYIKEKGNSGNHSLFRDRPTMRRMDEIAAMTDA
                     RRADQAWRQLDGEILKKAPAVPVLVRRWPLVLGGNIAGAYGQTSFGGQLDYASVGLKDP
                     AKSRA"
     misc_feature    3349..3359
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    complement(3373..3389)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.29"
                     /tool="antismash"
     misc_feature    complement(3375..3385)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            3528..4898
                     /locus_tag="HEK616_RS13810"
                     /old_locus_tag="HEK616_28060"
     CDS             3528..4898
                     /EC_number="3.4.11.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543307.1"
                     /locus_tag="HEK616_RS13810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_28060"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_261953236.1"
                     /transl_table=11
                     /translation="MTEAVPTAPRTVSHDLPVTPELERFLASGWAATPLPDAIRLSAAD
                     VTPARRQRLSARFPGERLIVPAGDLTVRSNDCDHRFRPHSAYAWLTGLTGEEQAGHVLV
                     LEPDGPHRHEAVLYLRPRSPRTDSGFARDRRYGEFWVGRRPDLAEAERMTGVRCVHLDG
                     LGALPPGRNAATDGQLASVLSELRLVKDAWEVAQLQLAVDHTTAGFEDVVRSLPRALAH
                     PRGERWIEGVFGLRARAEGNGTGYETIAAGGAHACVLHWIRNDGPLDARQLLLLDAGVE
                     TDTLYTADITRTLPLSGRFSPVQRQVYDLVLAAQEAGIAALRPGARFRDFHRAAMRVIA
                     EGLTDWGVLKDPEGDFHRRYTLCSSGHMLGLDVHDCAQARADAYLDGVLAEGQVLTVEP
                     GLYLQPDDETLPPDLRGIGVRIEDDLVITADGARLMSGALPRTPEAVEAWMGELMAG"
     misc_feature    complement(4967..4983)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 19.95"
                     /tool="antismash"
     misc_feature    4979..4989
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    4982..4997
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.3"
                     /tool="antismash"
     gene            5001..6158
                     /locus_tag="HEK616_RS13815"
                     /old_locus_tag="HEK616_28070"
     CDS             5001..6158
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642316.1"
                     /locus_tag="HEK616_RS13815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_28070"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_261953237.1"
                     /sec_met_domain="DAO (E-value: 2.3e-68, bitscore: 230.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTRNSPDLLVIGAGVVGAACAYYAARRGLHVTVLDRGSVAGGTT
                     GAGEGNLLVSDKEPGPELRLALYSTQLWRELAVVLPSRIEYEAKGGLVVASEEKGLSAL
                     REFAARQTEAGVTAEVVPGGRLRELEPHLAPGLAGGVHYPQDAQVQPALAAAHLLRAAG
                     DRVSLRLGEEVTAILTGAHGEVRGVRTPSGDLHAPYVVNAAGTWGGELARLAGVQLPVR
                     PRRGFVLVTEPLPRLVRRKVYAADYVADVASDSAALQTSAVVEGTPAGPVLIGASRERV
                     GFDRSLSVEALSRLAGQAVLLFPVLATVRAVRTYAGFRPYLPDHLPAIGPDPRRPGLLH
                     ACGHEGAGIGLAPATGRIIAETLTDGELPLDITPFRPDRFGGGEA"
     gene            6219..6542
                     /locus_tag="HEK616_RS13820"
                     /old_locus_tag="HEK616_28080"
     CDS             6219..6542
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309276.1"
                     /locus_tag="HEK616_RS13820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_28080"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_261953238.1"
                     /sec_met_domain="Fer2_4 (E-value: 1.3e-26, bitscore: 91.2,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARDRSPAELVGAAPDAAFEITFDGRPITALPGQSLAAALWAAGI
                     LAWRTTRVGGRPRGAFCGIGHCFDCLATVNGEPNRRACLVPARPGDAVTTQEGHGHDDL
                     AVR"
     gene            6520..8142
                     /locus_tag="HEK616_RS13825"
                     /old_locus_tag="HEK616_28090"
     CDS             6520..8142
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891273.1"
                     /locus_tag="HEK616_RS13825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_28090"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_261953239.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.4e-24, bitscore:
                     85.6, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 1.2e-10, bitscore:
                     40.4, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTISPSDDPEYDLAVIGAGAAGLAGAVTAAELGLSVALLDTSSQL
                     GGQFYRHPAPALGATRPEALHHDWSTFTDLRRRLTDSGVTHLAGHHVWTVVRAEPKDLW
                     DVHAVTGADGNGERPARVRARAVLLATGAYERQLPFPGWTLPGVVGAGGAQAMLKSGLV
                     VPGIGVSSVRAQPRAGIGVSSVRAQPRAGIGVSPARAQPRAGGRVVVAGSGPLLLAVAA
                     SLVTAGARVPAVVEAAGYLGYARHLRVLAANPHKMAEAAVHGTALLRHGVRLRTRSAVT
                     QVHGADRVEAVTVSRLDRDWRPVRGSGRRIACDALAVGFGLVPQLELATGLGCATRRTR
                     DGSHALDLDAQQQTSVPGIWAAGETGGIGGVQLACVEGELAGLAIAARLGGRPALTESG
                     RARALGRRRDRMRAFASVMAAAHAPGAGWTRWLDDTTDVCRCEEVSAGHIREAVADYGA
                     RDARTVKLLTRAGMGWCQGRMCGTAVACLAAEGPGAEPSPSPERRPLAVPVRLEVLGAL
                     AEVTASGAGDPEESADPEKGAGR"
     gene            8267..9187
                     /locus_tag="HEK616_RS13830"
                     /old_locus_tag="HEK616_28100"
     CDS             8267..9187
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543026.1"
                     /locus_tag="HEK616_RS13830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_28100"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_261953240.1"
                     /transl_table=11
                     /translation="MTTASTATTWSAERPWRGIMVATALPLRADRSVDHDAYAAHVRWL
                     LDNGCDGVVPNGSLGEYQTLTDEERARVVRTAVAAAGDGARVMPGVSAYGSAEARRWAE
                     QAAEEGCGSVLLLPPNAYRADESAVRAHYAEVARAGVPIVGYNNPIDTKVDLTPALLAR
                     LHGEGSIVAVKEFTGDVRRAYELAELAPGLDLLIGADDVLLELALAGAVGWIAGYPNAF
                     PAACAELYRAAVAQDLDTALPLYRSLHALLRWDSKTEFVQAIKLSMDIVGRHGGPTRPP
                     RLPLSGTVEAEVRAATEKTVAAGHR"
     gene            9201..10205
                     /locus_tag="HEK616_RS13835"
                     /old_locus_tag="HEK616_28110"
     CDS             9201..10205
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891275.1"
                     /locus_tag="HEK616_RS13835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_28110"
                     /product="proline racemase family protein"
                     /protein_id="WP_261953241.1"
                     /transl_table=11
                     /translation="MRTRHVFHAVDSHTEGMPTRVITGGVGVIPGTTMAERRLHFIEHL
                     DHLRTLLMYEPRGHASMSGAILQPPTRPDADYGVLFIEVSGLLPMCGHGTIGVATVLVE
                     TGMVEVTEPVTTVRLDTPAGLISVDVQVEDGRAESVTLTNVPAFCVGLDLTADVPGYGA
                     VTYDLAFGGNFYAFVDLDALGLPFDRARKDDLLAAGLALMDAINASPDRPVHPTRPEIA
                     GVKHVYLAAPGADAHHSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGALPLHRDFVNE
                     SFIGTRFTGRLVEETEIGHLPAVVPRITGRAWITGTAQYFLDPDDPFPGGFLL"
     gene            10202..11584
                     /locus_tag="HEK616_RS13840"
                     /old_locus_tag="HEK616_28120"
     CDS             10202..11584
                     /EC_number="1.2.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020548114.1"
                     /locus_tag="HEK616_RS13840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_28120"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_261953242.1"
                     /sec_met_domain="Aldedh (E-value: 5.6e-124, bitscore:
                     412.9, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTALAPVVSRNPADPSDVVVETAAPGAFAAADAVERARTAQPGW
                     LLDGAAARSAALGAIADAVEAAADELAALAVREVGKPVTEARAEVARTAAIWRYYAQTP
                     HDPTGAVHEPAAGPGLLLSRRRPHGVAGLITPWNFPFAIPTWKAAPALAAGNVVVLKPA
                     PEATGCALRLAEIVQQALPAGVFTVLPGGATEGDAVVSSADVISFTGSTAVGRAVARTA
                     TDRGVPVQAEMGGLNAAIVLPDADMDTAAAHIAAAVAGYAGQKCTATSRVIAVGAALAP
                     LREALAAHLRALPVGAPTDPATVCGPLINERARNRVVEARRGLPALVGTPAPVPSDGWY
                     AAPALLEHVPADHPLLREETFGPIAVLLPADDLDRAVRMTNSVPYGLVTSVHTASLDTA
                     LHGLDRLDTGMIRVNAPSTGVDFHLPFGGTKASSHGPREQGRAALDFYTSTRTYTLAPA
                     HP"
     misc_feature    complement(11591..11606)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.3"
                     /tool="antismash"
     misc_feature    complement(11602..11612)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.42"
                     /tool="antismash"
     misc_feature    11619..11633
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.19"
                     /tool="antismash"
     gene            11668..12384
                     /locus_tag="HEK616_RS13845"
                     /old_locus_tag="HEK616_28130"
     CDS             11668..12384
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091453.1"
                     /locus_tag="HEK616_RS13845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEK616_28130"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_261953243.1"
                     /transl_table=11
                     /translation="MGHLTQRNLNTTRERLRDQVAHHLRAALISGELRPGEVYSAPGLA
                     EDFGISATPVREAMLDLAREGLVEPVRNKGFRVTEVNERDLDQYTEIRTLIEVPMIGRI
                     TRSASREELEALRPVAEEIVRAARDHDLIGYLDADRQFHLSLLALAGNDRLVETVGDLR
                     KRSRLYGLTALDERDQLLPSAEEHIELLDLMVAGNAKAAEKCMARHLSHVRSLWAESAQ
                     ERTPARHGRNVRLSSH"
     misc_feature    complement(12695..12714)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 24.25"
                     /tool="antismash"
     misc_feature    12941..12955
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
ORIGIN
        1 ggggagcagc aggttcgacg cccagtgcgc ggggtcgtcg gcgaaggaga cgtaacgggg
       61 atagggcagc aggccggcca cccggatgag gccgtagatc agcatcatcg acgtgaagta
      121 gacgggcagc gaggcggcgc cgaccgcccc gaccatcagg gcgcggtcga cgagcgtgtc
      181 cttgcggagg gccgcgacca ccccggcgct caaaccgagc accagccaca gcacggccgc
      241 acccagggcg agcgacgcgg acaccggcag ccggtccacg aggaggtccc agacggcctc
      301 gctgttctcg tacgagtagc ccaggcaggg gaagtggcag tgcagggtgt accggccgct
      361 gcccatcgtg cggccggtga agatcccgga gacgaagtcc cagaactgcc gccacacggg
      421 ttcgtcgagc cccatgtgcg cccggatcgc ctccaggcgc tcggtgctgc acgacttgcc
      481 gcaggccgcg gcggccgggt cggagggcag gacgtagaag atcgtgaagg tgaccgcggc
      541 gacggcgatc agcactccga cgacggccac caggcgccgc agcgtgtagc ggatcatgcg
      601 cggcttcccc tcgggtcgag gacgtcgcgc agggcgtcgc cgagcagcgt gaacgcgagg
      661 acggtcagga acaggcaggc gctcgggatg acgaagtaca tggggtccgt gtcgtagaag
      721 gagacgctct cggcgatcat ctggccccat gagggggtgg gcggccgcac cccgacgccc
      781 aggtagctca gggccgcctc ggtggcgatc atcccgggga tgatgagggt ggtgtacgcg
      841 atgacgggcc cggcgacgcc cggcaggacg tcgcgggtga ggatgcgcca ggggccggag
      901 ccgccgacgc gggcggcgtc gacgtactcg cggtgcttga gggagagggt ctggccgcgc
      961 accacgcggg cgacgccggg ccagccgaag agcccgatga cggccgtcat cagcaggatc
     1021 cggttgacgt ccttggcgac cgacatcatc gcgatcatga agatgaggga ggggaaggac
     1081 atggtgaggt ccatcaggcg ggagagcagg gcgtcggtac ggccgccgaa gtagccggcc
     1141 gcgatcccgg ccgcggtccc ggtgacgacg acgatcgcgg tggccgtgag ggcgatgagc
     1201 agcgagacct gggcgccgtg cacgacccgg gcgaacaggt cgcgtccggt gaccggttcg
     1261 acgcccagcc agtggtcggc ggagatcccg ccgagcggtc cgaggggcgt accgccgagg
     1321 tacgggtcga cggcggactt gtcgaacgca tcgggcgacc agccgccgag cgcgctcagc
     1381 agcggggccg cggccgccat gaccaggaac agcccgatga tgacgaggga gatcttcacg
     1441 gagccgcggc ggcgcagttc acggcggacc agctgcccgg ggcggccgga cgcggtggac
     1501 aggggggccg cctccggggc gagcggctcg ggtgcggggg aggacatgat gggccggccc
     1561 ctcctcaagc ccggctcttg gcggggtctt tgaggccgac ggaggcgtag tccagctggc
     1621 cgccgaagga ggtctggccg taggcgcccg cgatgttgcc gccgagcacc aggggccagc
     1681 ggcgcaccag gaccgggacg gcgggggcct tcttgaggat ctcgccgtcg agttgccgcc
     1741 aggcctggtc ggcccgccgg gcgtcggtca tcgcggcgat ctcgtccatc cgccgcatgg
     1801 tcggccggtc gcggaagagc gagtggttgc cggagttgcc cttctccttg atgtaccggc
     1861 cgtcgaagac gaacggcagg aacgtcgagc cggaggggta gtcggggcac catccggtga
     1921 agaccaggtc ggtgcggttc ttggtgtcgc cgatggtggc gtagaacgcg gacggatcga
     1981 cggtgttgat ggcgaccttg atgccggcct tggccaggga ctgctggatg gcttcggccc
     2041 gtcccttgtc gccggaggac acggtgatct ccgtcgagaa gccgtccggc ttgcccgcct
     2101 ccttcagcag ctgcttggcc ttcgcgacgt ctccggtggt ggggatcttg agggtgtcgg
     2161 gctgctttcc gccgaagagc gaggcgggca tgtaggcggt ggacaggtcg ttgaaggccg
     2221 ggccgccgga cgcggtcagc accgagtccc tgtcgagggc gtactgcacc gcccgccgca
     2281 cccgtacatc ggtgaagggc gcccgcccgg tgtgcatctg gaccatgtcc gtgcagttcg
     2341 tcgactccgc cagcaggcgc gccctgacgt cggcgtgcgg cagcaccttg gccgcgctct
     2401 ccggccgcag cgcggaccag gggacggcgg aggcgtccgg gccctggccg gcgatgagcc
     2461 ggtcgtcgat ctggttggcc ttcagaccca tctccacgac cagccggtcc gggtaggcct
     2521 tgcgcaccgg gtcggtcttc gggtcccagt acggattgcg gaccaggacc aggcgcttgt
     2581 cccgcccgta cgactcgatc ttgtacggtc ccgaggagaa cggccggttg tcgtagcgcg
     2641 gtccgtcgtc gcgggcctgg ggcacgggcg cgaaggtcgg catcacggtg acgtcgggga
     2701 actccgcgaa gggcttgcgc agttcgaaga cgagggtgtg gtcgtccggc gtcttcacgg
     2761 aggcgaggtg ttcgccgtcc gcggggccct tgtacccctc ggcgccggcg aggtagcggg
     2821 ccgcgtagtc ggcgccgccg ggcaggtcgg gcgagaagga ccgctccacg ttgtacttga
     2881 tgtcccgcgc ggtgacgggt gtgccgtcct cgtatctgac gcccttcttg aggtggaagg
     2941 tccaggtccg ggcgccgtgg gacggggtgc cgaggtcggt ggcgaggtcg gggacgaggg
     3001 tgccgcccgc ggggccgggc gccgcccggt aggtcaccag ggtgcggtag agcaggcggg
     3061 tcccgaagtc catgtcgttc atgacccagt tgcgggccgg gtcgaggtgg gtgaagtcct
     3121 ggttggacag gacggtgagg gtgccgcccc gcttcggggt gccgccgacg accttgccct
     3181 ggttgaccag ggcggggttg gtgccgcggc ccctgccgtc cgcggagtcc ttgccgccgg
     3241 cacagccggt cgcgccgagg gcgagggccg ccgccaggca ggcggcggcg gtacgggtgc
     3301 gcttgttcat cagtggtcac tccgtgaaca gtcggacagc cgtcaggctg gaatgtgacc
     3361 cgtaacatag taatgtgaaa ttgcactgac aaggtgtcga ccgccccgtt atccagctgt
     3421 gcccgagtga actgccgccg gaggcggggc gtttgccctg tgacccgccc tgtgaaccgc
     3481 actgcgaacc gccctgtgaa ccgcaccgca atcgaggagg agaacccatg acggaagctg
     3541 ttcccaccgc cccgcggacc gtcagtcatg acctgcccgt cacgccggag ttggagcggt
     3601 tcctggcgag cggctgggcg gcgacgccgc tgccggacgc catccggctg tccgccgccg
     3661 acgtcacccc ggcccgccgg cagcgcctct ccgcccgctt ccccggcgaa cggctgatcg
     3721 tccccgccgg tgacctcacc gtccgctcca acgactgcga ccaccgcttc cggccgcaca
     3781 gcgcctacgc ctggctcacc ggcctgaccg gcgaggagca ggcgggtcac gtcctggtcc
     3841 tggagccgga cggaccgcac cggcacgagg cggtcctgta cctccgcccc cgctcgccgc
     3901 gcaccgacag cggcttcgcc cgggaccggc gctacggcga gttctgggtg ggtcgccgcc
     3961 ccgacctcgc cgaggccgag cgcatgaccg gcgtccgctg cgtccacctc gacggcctcg
     4021 gcgccctgcc gccggggcgc aacgccgcaa cggacggcca actggcatcc gtgctcagcg
     4081 agttgcggct cgtcaaggat gcctgggaag tcgcgcagct gcagctcgcc gtcgaccaca
     4141 cgaccgccgg gttcgaggac gtcgtccgca gtctgccgcg cgccctcgcc catccgcgcg
     4201 gcgagcgctg gatcgagggc gtcttcgggc tgcgggcccg cgccgagggc aacggcacgg
     4261 gctacgagac catcgcggcc ggcggcgccc acgcctgcgt cctgcactgg atacgcaacg
     4321 acggcccgct ggacgcccgc cagttgctcc tcctggacgc cggcgtggag accgacaccc
     4381 tctacaccgc cgacatcacc cgcaccctgc cgctctccgg acgcttctcc ccggtgcagc
     4441 ggcaggtgta cgacctggtg ctcgcggccc aggaggcggg catcgccgcg ctgcggccgg
     4501 gcgcacggtt ccgcgacttc caccgtgcgg cgatgcgggt gatcgcggag gggctcaccg
     4561 actggggcgt cctgaaggac ccggaagggg acttccaccg ccgctacacc ctctgcagca
     4621 gcgggcacat gctcgggctc gacgtgcacg actgcgccca ggcgcgggcc gacgcctatc
     4681 tggacggggt gctggcggaa ggtcaggtgc tgacggtcga gccggggctc tacctccagc
     4741 cggacgacga gacgctcccg ccggacctgc gcggcatcgg cgtacggatc gaggacgacc
     4801 tggtgatcac ggcggacggg gcgcggctga tgtcgggcgc cctgccgcgg acgcccgagg
     4861 cggtggaggc ctggatgggt gagctgatgg cgggctgagc tcacccgtca cctggggctt
     4921 ttccgggccg cggcaaggga attggcgcgg aggcggggag atcccttggc aacgtgggtg
     4981 caatgtgaaa tattactgac gtgcccacga gaaactctcc ggatctcctc gtcatcggcg
     5041 cgggcgtggt cggcgccgcc tgtgcctact atgcggcccg gcggggcctg cacgtcaccg
     5101 tgctcgaccg cggctccgtc gccggcggca ccaccggcgc cggcgaaggc aacctcctgg
     5161 tctccgacaa ggaacccggc cccgagctcc gactcgccct ctattccacg cagttgtggc
     5221 gcgaactggc cgtggtgctg ccgtcacgga tcgagtacga ggccaagggc ggcctcgtcg
     5281 tcgcctccga ggagaagggc ctgtccgcgc tgcgggaatt cgccgcacgg cagacggagg
     5341 ccggggtcac ggcggaagtg gtgccgggcg ggcggctccg tgaactggag ccgcacctcg
     5401 cccccggcct cgcgggtggc gtccactacc cgcaggacgc ccaggtgcag cccgccctcg
     5461 ccgccgccca cctgttgcgc gcggccggcg accgggtgag cctccggctc ggcgaggagg
     5521 tcaccgcgat cctcaccggc gcccacggcg aggtgcgcgg agtgcggacg ccttccggtg
     5581 acctccacgc tccctacgtc gtgaacgcgg cggggacatg gggcggcgag ctggcccggc
     5641 tcgccggcgt gcagctgccg gtgcggcccc ggcgcggctt cgtgctggtc accgagccgc
     5701 tgccgcgcct ggtgcggcgc aaggtgtacg ccgcggacta cgtcgccgac gtcgccagcg
     5761 actcggcggc cctgcagacc tccgccgttg tcgagggcac cccggcgggc ccggtcctga
     5821 tcggcgcgag ccgggagcgg gtcggcttcg accgctcact gtcggtggaa gcactgagcc
     5881 gcctggccgg gcaggcggtc ctgctcttcc cggtcctcgc cacggtgcgg gccgtgcgga
     5941 cgtacgcggg cttccgcccc tacctgcccg atcacctgcc cgcgatcggg cccgatccgc
     6001 gccgaccggg gttgctgcac gcctgcggcc acgaaggagc gggcatcggc ctcgccccag
     6061 ccaccggacg gatcatcgcc gagaccctga cggacggcga actcccgctg gacatcaccc
     6121 cgttcagacc cgaccggttc ggcgggggag aggcgtgatg gccgcttcgc cggcccctcg
     6181 ccgcccccgc accgaccccc tgcgaaagga gccgtgtcat ggcgcgtgac cgcagccccg
     6241 ccgagctcgt cggcgcggcg cccgacgccg cgttcgagat caccttcgac ggccgcccga
     6301 tcaccgcgct gcccggccag tccctggccg ccgcgctgtg ggccgccggc atcctcgcct
     6361 ggcgcaccac ccgcgtcggc ggccggccgc gcggcgcctt ctgcggcatc gggcactgct
     6421 tcgactgcct cgccaccgtc aacggagaac ccaaccgccg ggcctgcctg gtcccggcgc
     6481 ggcccggcga cgccgtcacg acccaggagg gacacggcca tgacgatctc gccgtccgat
     6541 gacccggagt acgacctcgc ggtgatcggg gccggcgccg cgggcctcgc cggtgccgtc
     6601 accgccgccg aactcggcct gtccgtcgcc ctgttggaca cctcgtcaca gctgggcggg
     6661 cagttctacc ggcaccccgc cccggccctc ggcgccaccc gccccgaggc gctgcaccac
     6721 gactggtcca ccttcaccga cctgcgccgt cgcctgaccg acagcggcgt gacccatctc
     6781 gccggacacc atgtctggac cgtcgtccgc gcggagccca aggacctgtg ggacgtgcac
     6841 gccgtgaccg gagcggacgg caatggggag cgcccggccc gggtccgggc ccgcgcggtg
     6901 ctgctcgcga ccggcgcgta cgagcggcaa ctgccgttcc ccggctggac gttgccgggc
     6961 gtggtgggtg ccgggggagc gcaggcgatg ctcaagtccg gcttggtggt gcctgggatt
     7021 ggggtctcct ctgtgcgggc gcagccgaga gctgggattg gggtctcctc tgtgcgggcg
     7081 cagccgagag ctgggattgg ggtctcccct gctcgagcgc agccgagagc tgggggaagg
     7141 gtcgtggtgg cgggcagtgg tccgctgctg ctggccgtcg ccgcctcgct cgtcacggcg
     7201 ggggcccgcg tcccggcggt ggtcgaggcg gccggctacc tcggctacgc ccgccacctc
     7261 cgcgttctcg ccgccaaccc gcacaagatg gcggaggcgg cggtgcacgg cacggcgctc
     7321 ctgcggcacg gggtgcggct gcgcacccgc agcgcggtga cccaggtgca cggggccgac
     7381 cgggtggagg ccgtcacggt ctcccggctc gaccgcgact ggcggcccgt acgggggtcg
     7441 ggccgccgga tcgcctgcga cgccctggcg gtcggcttcg gtctcgtccc gcagctcgaa
     7501 ctcgccaccg gcctgggctg cgccacccgg cgcacccggg acggcagcca cgccctcgac
     7561 ctcgacgcac agcagcagac ctcggtaccc ggcatctggg cggcgggcga gacaggcggc
     7621 atcggtggcg tgcaactcgc atgcgtggaa ggcgagttgg cgggtctcgc gatcgcggcc
     7681 cggctcggcg ggcggcccgc gctcaccgaa agcgggcggg cccgtgccct gggccgccgg
     7741 cgcgaccgga tgcgcgcctt cgcgtccgtg atggccgcgg cacacgcacc cggcgccgga
     7801 tggacccggt ggctcgacga caccacggac gtctgccgct gcgaggaggt cagcgccggc
     7861 cacatccgcg aggcggtcgc cgactacggc gcccgggacg cccgcaccgt caaactcctc
     7921 acccgcgccg gcatgggctg gtgccagggc cggatgtgcg ggaccgccgt ggcctgcctg
     7981 gccgcggagg ggccgggagc ggagccgtcg ccgtctccgg agcgccgccc gctggccgtg
     8041 cccgtccggc tggaggtgct cggtgccctc gcggaggtga ccgcatccgg ggccggcgat
     8101 ccggaggaaa gcgccgatcc ggagaagggc gccggccgct gaccggacgc gccgccccca
     8161 ccgcccgcgc ccctgggtac cacgcaccac cacacgccat gccacacccc gcagaacccg
     8221 tcacagacac ccgtccacag acacccgtcc acagaagggc tccctcatga ccaccgcctc
     8281 caccgccacg acctggagcg ccgaacgccc ctggcgcggc atcatggtcg ccaccgccct
     8341 gcccctgcgt gcggaccggt ccgtcgacca tgacgcctac gccgcacacg tccgctggct
     8401 cctcgacaac ggctgcgacg gcgtggtgcc gaacggctcg ctgggcgagt accagaccct
     8461 gaccgacgag gaacgtgccc gcgtggtgcg caccgccgtc gcggccgccg gcgacggtgc
     8521 gcgcgtgatg cccggcgtgt ccgcgtacgg cagcgccgag gcccgccggt gggccgagca
     8581 ggccgccgaa gagggctgcg gcagcgtcct gctgctgccg cccaacgcct accgcgccga
     8641 cgagtcggcc gtacgggccc actacgccga ggtcgcccgg gccggcgtgc cgatcgtggg
     8701 ctacaacaac cccatcgaca ccaaggtcga cctgaccccc gcgctgctcg cccgcctcca
     8761 cggcgagggc agcatcgtcg cggtcaagga gttcaccggc gatgtgcgcc gggcgtacga
     8821 actggccgaa ctcgcccccg gactggacct gttgatcggc gccgacgacg tgctcctgga
     8881 gctcgcgctg gccggggctg tgggctggat cgccggatac cccaacgcct tccccgccgc
     8941 ctgcgccgag ctctaccgtg ccgccgtggc ccaggacctg gacaccgccc tgccgctgta
     9001 ccggtccctg cacgccctgc tgcgctggga ctccaagacc gagttcgtgc aggccatcaa
     9061 gctctccatg gacatcgtcg gccgccacgg cggcccgacc cggccgcctc gtctgccact
     9121 gtccggcact gtcgaggccg aggtgcgggc agccaccgag aagaccgtcg ccgccggcca
     9181 ccgctgaccg ggaggagacc atgcgcaccc gccacgtctt ccacgccgtc gactcacaca
     9241 ccgaaggcat gcccacccgc gtgatcaccg gcggcgtcgg ggtgatcccc ggcaccacca
     9301 tggccgagcg ccggctgcac ttcatcgagc acctggacca cctgcgcacc ctgctcatgt
     9361 acgagccgcg gggccacgcc tccatgagcg gcgccatcct ccagcccccg acccggcccg
     9421 acgccgacta cggcgtgctg ttcatcgagg tctccggcct cctgccgatg tgcggacacg
     9481 gcaccatcgg ggtggccacc gtcctcgtcg agaccggcat ggtcgaggtc accgagcccg
     9541 tgaccaccgt ccgcctcgac acccccgccg gcctgatcag cgtcgacgtc caggtcgagg
     9601 acggacgggc cgagtccgtc acgctcacca acgtgcccgc cttctgcgtc ggcctcgacc
     9661 tcacggcgga cgtaccgggc tacggcgcgg tgacgtacga cctcgccttc ggcggcaact
     9721 tctacgcctt cgtcgatctc gacgccctgg ggctgccgtt cgaccgcgcc cgcaaggacg
     9781 atctgctcgc cgcggggctc gccctcatgg acgcgatcaa cgcctcgccc gaccggcccg
     9841 tccacccgac ccggccggag atcgcgggcg tcaaacacgt ctacctcgcc gccccgggcg
     9901 cggacgccca ccactcccgg cacgccatgg ccatccaccc gggctggttc gaccgctcgc
     9961 cgtgcggcac cggcaccagt gcgcggatgg cccagctgca cgcccgcggc gccctgcccc
    10021 tgcaccgcga cttcgtcaac gagtccttca tcggcacccg gttcaccggg cggctcgtcg
    10081 aagagaccga gatcgggcac ctgcccgccg tcgtgccccg catcaccggg cgggcctgga
    10141 tcaccggcac cgcccagtac ttcctggacc ccgacgaccc cttccccgga ggtttcctcc
    10201 tgtgagcacc gccctggccc cggttgtctc ccgcaacccg gccgacccct ccgacgtggt
    10261 cgtggagacc gccgcacccg gcgcgttcgc cgccgccgac gccgtcgaac gcgcccgcac
    10321 cgcacagccc ggctggctgc tcgacggcgc ggccgcccgc tcggccgccc tcggcgcgat
    10381 cgccgacgcc gtcgaggcgg ccgcggacga actggccgcg ctcgccgtac gcgaggtggg
    10441 caaaccggtc accgaagccc gcgccgaggt ggcccgcacc gccgcgatct ggcgctacta
    10501 cgcccagacc ccgcacgacc ccaccggcgc ggtccacgag ccggccgccg gccccggact
    10561 gctgctcagc cgccgccggc cgcacggcgt cgccggcctg atcaccccct ggaacttccc
    10621 gttcgccatc cccacctgga aggcggcccc cgcgctcgcc gccggcaacg tggtcgtact
    10681 gaaacccgca cccgaagcca ccggctgcgc gctgcgcctg gccgagatcg tgcaacaggc
    10741 gctgcccgcc ggggtgttca cggtgctgcc cggcggtgcc accgagggtg acgccgtcgt
    10801 ctcgtccgcc gacgtcatct ccttcaccgg ctccaccgcg gtcggccggg ccgtcgcgcg
    10861 gaccgccacc gaccgaggtg tccccgtaca ggccgagatg ggcgggctga acgcggcgat
    10921 cgtcctgccg gacgccgaca tggacaccgc ggccgcacac atcgccgccg ccgtcgccgg
    10981 atacgccggc cagaagtgca ccgccaccag ccgcgtgatc gccgtggggg cggccctcgc
    11041 gccgctgcgc gaggcactgg ccgcacacct gcgggccctg ccggtgggcg cccccaccga
    11101 ccccgccacc gtctgcggcc ccctcatcaa cgaacgggcc cgcaaccggg tggtcgaggc
    11161 ccgccgggga ctgcccgcac tcgtgggcac ccccgcgccc gtcccgagcg acggctggta
    11221 cgcggcgccg gccctgttgg agcacgtccc cgccgaccac ccgctcctgc gggaggagac
    11281 cttcggcccg atcgccgtac tgctccccgc cgacgacctg gaccgggcgg tgcggatgac
    11341 caactccgtt ccgtacggcc tggtcacctc ggtacacacg gcatccctcg acaccgccct
    11401 gcacggactc gaccggctcg acaccggcat gatccgggtc aacgcccctt ccaccggtgt
    11461 cgacttccac ctgccgttcg ggggcaccaa ggcatccagc cacggaccgc gcgaacaggg
    11521 ccgcgccgcc ctggacttct acacctcgac ccgcacctac accctcgccc ccgcacaccc
    11581 gtagccacct gcgaaaacaa cgtgacattg tacgctggtg atccgctcgg ccacgaggga
    11641 caagggcacg aagggaaaca ccacgacatg ggccacctca cgcagcgcaa tctcaacacc
    11701 accagggagc gcctgcgcga ccaggtcgcc caccacctgc gggcggccct gatctcgggc
    11761 gaactccgcc ccggcgaggt ctactcggca cccggtctcg cggaggactt cggcatctcc
    11821 gcgacgccgg tgcgcgaggc gatgctcgac ctggcccgcg aaggcctggt cgaacccgtc
    11881 cgcaacaagg gcttccgggt caccgaggtc aacgagcgcg acctcgacca gtacaccgag
    11941 atccgcaccc tcatcgaggt ccccatgatc ggccgcatca cgcgcagcgc gtcccgcgag
    12001 gagctggagg cgctgcgccc ggtcgccgag gagatcgtgc gcgccgcccg cgaccacgac
    12061 ctcatcggct acctcgacgc cgaccgccag ttccacctct ccctcctcgc gctcgccggg
    12121 aacgaccggc tcgtggagac ggtcggtgac ctgcgcaagc gctcccgcct gtacggcctg
    12181 accgccctgg acgaacgcga ccagctgctc ccctcggccg aggagcacat cgaactcctc
    12241 gacctgatgg tggccggcaa cgccaaggcc gccgagaagt gcatggcccg ccacctgagc
    12301 cacgtccgct ccctgtgggc ggagagcgcg caggaacgca cccccgcccg gcacggccgc
    12361 aatgtccgcc tgagttccca ctgacgaccg gaccccgccc ggggcggacc ggccggtgcc
    12421 gggccgtgca caacacggcg tgatggccga gcgggagttc ccccggacgt gcggtgacca
    12481 cagactgtct gtcccaggcc ggtccgacca cacctcaccc acgcgcccgg gaagggacca
    12541 tgaaccccgc acacaccacc gtcgaccaca ccttcacggt ccccttggac cacgccgccc
    12601 ccggcggcga gacgatacgc atcttcgccc gcgagatcac cgaccgctcc cgcgccggcg
    12661 aggaactgcc ctggctgctc tatctgcagg gcggcccggg cggcaagtcc ccccgcccgt
    12721 cgggcacctc gcccggctgg ctggcccacg cactgaccac gcaccgcgtc ctcctcctcg
    12781 accagagggg caccggccgc tccaccccgg tcaccgcccg gtccgccgcg cgttgtgagg
    12841 acccggccca actcgccgca tatctgggcc acttcagggc cgactcgatc gtcgccgatg
    12901 ccgagctgat ccgccacacg ctgtgcggtg gggagcgctg ggagacgctc ggccagagct
    12961 acggcggctt cctcaccctc acctacctct cccaggcccc ggaaggactc cgggcctgct
    13021 acgtcgccgg cggcctcccg ggcctcacgg ccaccgccga cgacgtctac gcccgcacct
    13081 atccacgcgt gcgcgaccgg gtccacgagt tctacgcccg ctatccggac gacgcccgat
    13141 gt
//
