LOCUS       NZ_JANAVN010000023     27607 bp    DNA     linear   CON 26-JUL-2024
DEFINITION  Paenibacillus sp. Lou8.1 NODE_23_length_71293_cov_144.041550, whole
            genome shotgun sequence.
ACCESSION   NZ_JANAVN010000023
VERSION     NZ_JANAVN010000023.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. Lou8.1
  ORGANISM  Paenibacillus sp. Lou8.1
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 71293)
  AUTHORS   Gonzalez-Pimentel,J.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAY-2022) Agroquimica, Microbiologia Ambiental y
            Conservacion de Suelos, Instituto de Recursos Naturales y
            Agrobiologia, Av. Reina Mercedes 10, Sevilla 41012, Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024213565.1-RS_2024_07_26
            Annotation Date                   :: 07/26/2024 02:53:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,316
            CDSs (total)                      :: 5,255
            Genes (coding)                    :: 5,159
            CDSs (with protein)               :: 5,159
            Genes (RNA)                       :: 61
            rRNAs                             :: 3, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 40 of 96
            Pseudo Genes (incomplete)         :: 74 of 96
            Pseudo Genes (internal stop)      :: 9 of 96
            Pseudo Genes (multiple problems)  :: 25 of 96
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:00:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 43686
            Orig. end                         :: 71293
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JANAVN010000023.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..27607
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..27607
                     /SMILES="NCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27607
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:>27607](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>27607
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     misc_feature    149..164
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.65"
                     /tool="antismash"
     misc_feature    313..331
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.85"
                     /tool="antismash"
     gene            357..1271
                     /locus_tag="NLX78_RS25045"
                     /old_locus_tag="NLX78_25035"
     CDS             357..1271
                     /EC_number="3.5.3.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009330115.1"
                     /locus_tag="NLX78_RS25045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25035"
                     /product="arginase family protein"
                     /protein_id="WP_061830919.1"
                     /transl_table=11
                     /translation="MTEKTIRLLMPQWQGGNNPNYSFGAELLAWLAPDNDQPLIHVPIQ
                     AYNGTPLENENGMNGRKQLLEQLEAAQHIIDAHKPDRIVMFGGDCLVEQAPFAYLNERY
                     GGELGLIWIDAHSDLVRYVGYDNGHTLPLGNLLGEGDEEFAKHVKIPLKPENVFIAGLA
                     APTEQETEAISEAFQRLGIAPAESDTEVIQRLGIKTAGTKELTNSTESIREWIKESGIK
                     HLAIHLDLDVLDPKAFRSLLFANPEAPYNFSPAGTMQMPQLLNLIKELSEETDVVGLGI
                     TEHMPWDAINLKNLLGEIPILNK"
     gene            1505..1609
                     /locus_tag="NLX78_RS25050"
                     /old_locus_tag="NLX78_25040"
     CDS             1505..1609
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015735743.1"
                     /locus_tag="NLX78_RS25050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25040"
                     /product="DUF6254 family protein"
                     /protein_id="WP_023988604.1"
                     /transl_table=11
                     /translation="MAHQKKRKEAAWKSRKQEQHPHGKVKSLKELSSE"
     gene            complement(2140..3024)
                     /gene="dapA"
                     /locus_tag="NLX78_RS25055"
                     /old_locus_tag="NLX78_25045"
     CDS             complement(2140..3024)
                     /EC_number="4.3.3.7"
                     /GO_function="GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /gene="dapA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310353.1"
                     /locus_tag="NLX78_RS25055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25045"
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="WP_367988755.1"
                     /transl_table=11
                     /translation="MMMNEQHIHGIFIPLITPFTRDYKLDIDSYRKYVTYLAGHDIQGL
                     VVNGTTGESPTVSWDEVKLMVHVTQDVLKIMNKTIPIVIGTGTNDTYSTVHRTEMAAEL
                     GADAAMVVTPYYNRPTQEGILEHFRVVSRVGLPVLVYEIPVRTGSRMTIDTIRKVLDLD
                     GIIGLKDSTGGLDLLLKLAQYETKPVLCGEDAYFHAMLCQGATGGMLASAHLHIQKYVD
                     IYQRFVAGDMNGSRDSFMLLEPMIQHVFAEPAPAAIKWWLTQQEIIAAEQLRLPLMPLS
                     DQVKQGLLNSIIS"
     gene            3097..4005
                     /locus_tag="NLX78_RS25060"
                     /old_locus_tag="NLX78_25050"
     CDS             3097..4005
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310354.1"
                     /locus_tag="NLX78_RS25060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25050"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_367988757.1"
                     /transl_table=11
                     /translation="MILIKIFDGVARLDFIYLQTFREVAIRESFTRAAEVLGYAQSSVT
                     TQIQKLEKTYQVKLFERYNNNKIRLTSAGEELFKLAGQMLELFEQSKEKLAKQGGGSMT
                     IGTMDSIASYFLPPYMQATRKEYPDLNIRLHTDREEMILHQVREGEADVGLILADDSSN
                     PALQWITIREEPLVLIVHPNHPLIAKEQIDLNDLVDAEWIMPEHTCNYRQLLERVLRAN
                     GITYRVSLELGNPEAIKRSIKTGEGISILPLMAALEEIEREELKVLPFEHAELKLEIQL
                     VLHPKKWVSNALSFFMESMRI"
     misc_feature    3106..3120
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.82"
                     /tool="antismash"
     misc_feature    complement(4200..4216)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.88"
                     /tool="antismash"
     gene            4294..>4413
                     /locus_tag="NLX78_RS25065"
                     /old_locus_tag="NLX78_25055"
                     /pseudo=""
     CDS             4294..>4413
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003353985.1"
                     /locus_tag="NLX78_RS25065"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25055"
                     /product="NAD(P)H-binding protein"
                     /pseudo=""
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.4e-07, bitscore:
                     20.8, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVLVVGSNGQIGQHLIHFLKENKEHTVRAMVRKQEQANA"
     misc_feature    complement(4939..4956)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            5077..5928
                     /locus_tag="NLX78_RS25070"
                     /old_locus_tag="NLX78_25060"
     CDS             5077..5928
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NLX78_RS25070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NLX78_25060"
                     /product="hypothetical protein"
                     /protein_id="WP_254351827.1"
                     /transl_table=11
                     /translation="MKLEKQQEKKSYDNVLAKLDPKKRDEVSKRFDLIQPLILLEKIKN
                     GNIQAVSKFNDKYKELLHEDEEVFKLKQEELISKIVKKFGGSRATIMRILANYRKYEDA
                     SISRGLERLISNKGKGYTGRKDNKVMTICHPERQEIVLDTILVRLTDKQIEILKENLER
                     DYLNKYRVSKATIHRLVERRCAKVNEAEVKYSTISDIIDRIDKQAVERLRNINKAKTIY
                     DEVARGYANREAIYRLDIIQMDHTRLDMQVIDDVTGLVIKPAATKPTGSRRKSAADDKK
                     TE"
     gene            complement(6206..6817)
                     /locus_tag="NLX78_RS25075"
                     /old_locus_tag="NLX78_25065"
     CDS             complement(6206..6817)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372237.1"
                     /locus_tag="NLX78_RS25075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25065"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_081112483.1"
                     /transl_table=11
                     /translation="MMNSESQSVSLKIPREELNRRRILAAARELFIKNGVDNVNMHQIA
                     KTAGVGQASLYRRYSDKGDICQEIAYEEYQPLFDEVQAFLDQSPETAALDRLYHVIVRY
                     VSFLEAKVPWLCEVSRASTGHRPLQSPLCQWMRNISRNLLNEAVEQGDVSGVDISYTIE
                     ALLAVLHNIDYHLQDEGFTSQRVLDGLHRIFIEGLRANRH"
     gene            complement(6976..7167)
                     /locus_tag="NLX78_RS25080"
                     /old_locus_tag="NLX78_25070"
     CDS             complement(6976..7167)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372236.1"
                     /locus_tag="NLX78_RS25080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25070"
                     /product="hypothetical protein"
                     /protein_id="WP_029515917.1"
                     /transl_table=11
                     /translation="MDQKQLNSEVSRKASTETGTDTTSDKKKAYEQFIHTIASLKELDL
                     SGIEPHLPPIYKKHYTKK"
     gene            complement(7197..8585)
                     /locus_tag="NLX78_RS25085"
                     /old_locus_tag="NLX78_25075"
     CDS             complement(7197..8585)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372235.1"
                     /locus_tag="NLX78_RS25085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25075"
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     GatCAB subunit A"
                     /protein_id="WP_029515916.1"
                     /transl_table=11
                     /translation="MSKLNFQLSFAAIHELAEGIRTREISPVEITEHALHRIERLNPKL
                     NVFVTQTSELAIEQAKQSERDIMHGRYKGPLHGIPIVHKDLYYTKGIRTTAGSKILNSF
                     VPDYDSTVAAKLHEAGTVLLGKVQTHEFAAGLTTTSPHFGPCLNPWNTELVTGGSSGGS
                     ASALAAGLTYLGTGSDTGGSIRIPAALCGVVGMKPTYGRVSRYGIIPMAWSLDHSGPLT
                     RCVMDASLCLDVMSGFDPKDESTVDLPAPGIKMYPNGLRGVRIGLPTSYYYEDLMPEVE
                     AAMKAAINKFRELGAEIIEVSLPLIKHVRSATMAIMMTEMYSYHEKWLETELEQYGPDV
                     RMFLESSRDIPASIYLQSQRARQLIVNDFLNALSGIDILLTPATPITAPRADDDASVFR
                     LNSFTVPTNLTGLPSLSMPCGFSPSGLPINMQLIGRPFEEATVLGIGNTYEMNTDWHKR
                     HPDL"
     gene            complement(8631..9953)
                     /locus_tag="NLX78_RS25090"
                     /old_locus_tag="NLX78_25080"
     CDS             complement(8631..9953)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372234.1"
                     /locus_tag="NLX78_RS25090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25080"
                     /product="MFS transporter"
                     /protein_id="WP_061830911.1"
                     /transl_table=11
                     /translation="MDTQSMALSGNERKLMGTLCLLIIFGNINMTMFNLSIPSISADFA
                     LTSSQVSWVMVGYSILMAIGAGTYGKLTESFSFRQLYVIGLILLAFGSMIGFFAASYLQ
                     VIIGRLLQAAGASSISPLSYAAVTLYFKPTVKGRVLGTLSATIAFASGFGPVFGGFVEQ
                     YFGWRALFIVSSLSLFVIPLIFKYVPDKKHDRGSFDFLGAVLFSAGLALVLLGVTNYWF
                     MLIAGAAVLLWFGTHIQKKEHPFIDASFMKNAPYRRILGIGFLTFVCNTGLTFTLPVMM
                     KNSFHLPTSKIGLLMLPGAACAALLGSRIGGWTDRFGSSRVLVISQSLVISGFILLGVS
                     VHLPPWIDALLIIILMIGFNGVLTSSSNLVSTTLRSAELGVGMGIFTLAYLLGGAFGPA
                     LVGRLIDLKMPFSVVYFTISLLAILTYLFARKANRSGSYGN"
     gene            complement(9968..10726)
                     /gene="aiiA"
                     /locus_tag="NLX78_RS25095"
                     /old_locus_tag="NLX78_25085"
     CDS             complement(9968..10726)
                     /EC_number="3.1.1.81"
                     /GO_function="GO:0102007 - acyl-L-homoserine-lactone
                     lactonohydrolase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="aiiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216572.1"
                     /locus_tag="NLX78_RS25095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25085"
                     /product="N-acyl homoserine lactonase AiiA"
                     /protein_id="WP_165179822.1"
                     /transl_table=11
                     /translation="MNIKKLYFLPVGECFLDQSAVNRTLAPGKLVGMPVWSFLLETTSG
                     PILIDTGMPDAFINNPDYYKGTRREGRVVPNMSDGDSIVNVLKRVGYRPDDIQMVISSH
                     LHLDHSGGNGHFRNTPILIQRAEYDAAINNEDYSPLECRLPDLQYQIIEGDHELIPGVQ
                     ILFTPGHSPGHQSVLVTTEKSGPVLLTIDVAYTRENFENSVPFLTFDQEMAAKSITRMQ
                     ELIQDVRPSYVFLGHDRDQAQKCRTFPDFL"
     misc_feature    10778..10792
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.72"
                     /tool="antismash"
     gene            <11044..11271
                     /locus_tag="NLX78_RS25100"
                     /old_locus_tag="NLX78_25090"
                     /pseudo=""
     CDS             <11044..11271
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003248428.1"
                     /locus_tag="NLX78_RS25100"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25090"
                     /product="NAD(P)H-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="LESSSLNYTIIRLGILLNEIGTGKVAAAENITYGSIPREDVARAI
                     VAALDEGNTYKRAFDLITGDDSVVEALQKI"
     misc_feature    complement(11383..11396)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.22"
                     /tool="antismash"
     gene            11445..12467
                     /locus_tag="NLX78_RS25105"
                     /old_locus_tag="NLX78_25095"
     CDS             11445..12467
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371141.1"
                     /locus_tag="NLX78_RS25105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25095"
                     /product="NADH:flavin oxidoreductase/NADH oxidase"
                     /protein_id="WP_069291934.1"
                     /transl_table=11
                     /translation="MKDLFSPYTIKGLELKNRVVMPPMCQYSVDKKDGVATDWHYIHYV
                     SRAVGGAGFIIIEMTDVEPDGRISDFDLGLWSDEQIPALKRIVDACHSYGAKVGIQIAH
                     AGRKAEDAEVPVAPSAIAFDENSKQPRALTTEEVKGLVEKFRAAVARAVKAGFDSIEIH
                     GAHGYLIHQFHSPLTNKREDEYGKDLTLFGREIIQAAKGEMPEDMPLLMRISAKEYVEG
                     GYGIKESIAFAKEYQKAGVDMFDISSGGEGPIAAWGRPGTHAAYQVPLAKDIKEALDIP
                     VMAVGRLEDPILANAVIGNEEADLVAVGRGMLRNPYWSLEAASKLKKETAIPTQYTTGF
                     "
     gene            13036..13446
                     /locus_tag="NLX78_RS25110"
                     /old_locus_tag="NLX78_25100"
     CDS             13036..13446
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019687272.1"
                     /locus_tag="NLX78_RS25110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25100"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_250268342.1"
                     /transl_table=11
                     /translation="MDYKSLATELFEYIVKSRKPALEERGHFSRGEMGILICLNFNKDG
                     VTSGHLSEYLSVSTGRVATALKSLEKKGLVVRRTDVNDKRKVIVFITDSGKQFMIDRHN
                     EGIAWTENVLRKLDEEDAKELIRLIKLIVSRS"
     gene            13521..15284
                     /locus_tag="NLX78_RS25115"
                     /old_locus_tag="NLX78_25105"
     CDS             13521..15284
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007428745.1"
                     /locus_tag="NLX78_RS25115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25105"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_250268343.1"
                     /transl_table=11
                     /translation="MLKIFKYLKKNEWMLVLCSLAFIVVQVWLDLKLPDYMAEITTKLQ
                     TEGTPVSELLIPGSYMLFCAVGSMIASIIVGYFAAKVAAGLAMRLRAMVFDKTLSFSME
                     EMNSFSTASLITRSTNDVTQIQTVVALGLQVIIKAPILAVWAIVKIADKNWQWTASTGA
                     AVAVLILMLSVIVVFALPSFQRIQRLTDNLNRVTREHLIGLRVVRAYNADQYQQEKFEQ
                     ANVELTNTNLFANRLMTMIGPGMTFIMSGLSVSIYCIGAYLINGAAVPDRITLFSNMVV
                     FSSYAMQVVMAFMMVSMIFILMPRASISAKRIMEVLNTESSIVNGHETTGEESVMGQVE
                     FRNVSFKYPDAEEAVLRNISFTAKQGETVAFIGATGSGKTSVINLIPRFYDVTEGEVLV
                     DGVNVRDYNQQALHNKIGYVPQRAVLFHGTVVSNVSYGDNGRAGASEKLVKEAVGIAQG
                     TEFVEKMDGQYQGRISQGGANVSGGQKQRLSIARAIYRQPEIYIFDDSFSALDYRTDRI
                     LRSALKKETGHATTLIVGQRIGTIKDADRIIVLDQGEIVGSGTHEELMTNCSTYQEIAY
                     SQLSKEELIHG"
     gene            15277..17127
                     /locus_tag="NLX78_RS25120"
                     /old_locus_tag="NLX78_25110"
     CDS             15277..17127
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014282475.1"
                     /locus_tag="NLX78_RS25120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25110"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_250261360.1"
                     /transl_table=11
                     /translation="MDKNEHTVDSQQMKMNQRGPMGKGPAGGKGTGEKANNFKKTISQL
                     VSYSKAYVPMIILAMVLALVGSTLNVIGPDKLSDIANLIQEGIVTGIDVSAVQKIVLVL
                     ALLYGFGLIFNYFQGFITATVSQRLTKKMRTELSRKIDHMPLKYFDSTSYGNVLSRVTN
                     DVDTIGQTLNNSLGTLVSALATFVGALIMMLYTNWIMTVTGIIATLIGFCLMSVIMKHS
                     QKYFVAQQAELGQINGHIEETYAGHNVVKVYNGEQAAKEVFHGINSRLYTNAWKSQFMS
                     GLMMPVMMFIGNFGYVAVCVVGALLVNQQTITIGTIVAFMVYIRLFTQPLSQLAQAATN
                     LQSAAAASERVFEFLGEEELADERHKTIKLDTAKGDVEFKHVRFGYNADRMIIKDFSMK
                     AEAGQKIAIVGPTGAGKTTLVNLLMRFYELNDGEIYIDGTPISQLTRENIHELFCMVLQ
                     DTWLFEGTIRDNIVFSKDHVTDEQVEAACRAVGLHSFIKTLPQGYDTVLDDKANLSAGQ
                     KQLITIARAMIEDSPMLILDEATSSVDTRTELLIQQAMDQLTVGKTSFVIAHRLSTIKN
                     ADLILVMKDGDIIEMGNHEELLAKGGFYADLYNSQFEHAS"
     misc_feature    17235..17248
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.93"
                     /tool="antismash"
     gene            17248..17556
                     /locus_tag="NLX78_RS25125"
                     /old_locus_tag="NLX78_25115"
     CDS             17248..17556
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310359.1"
                     /locus_tag="NLX78_RS25125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25115"
                     /product="hypothetical protein"
                     /protein_id="WP_061830895.1"
                     /transl_table=11
                     /translation="MNQRFRITRSMQESPVEQSITLEECKDYFASQPDFSYSRVLIIQG
                     AESTMSIEGDFFMWKYADVEIPFRHYMGDVYVAISDEAVVPKMIEIATDLQADVVDG"
     gene            17856..18026
                     /locus_tag="NLX78_RS25130"
                     /old_locus_tag="NLX78_25120"
     CDS             17856..18026
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NLX78_RS25130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NLX78_25120"
                     /product="hypothetical protein"
                     /protein_id="WP_155765266.1"
                     /transl_table=11
                     /translation="MTVKSGDLIIALDGALMEISSSEQFGLSGWAVSARLYGMFSEEYS
                     NEIVLRKKTVG"
     misc_feature    18182..18200
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.83"
                     /tool="antismash"
     misc_feature    18231..18246
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     misc_feature    complement(18282..18298)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 23.28"
                     /tool="antismash"
     misc_feature    complement(18367..18381)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.38"
                     /tool="antismash"
     misc_feature    18666..18683
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: strong, score: 21.55"
                     /tool="antismash"
     gene            20001..>27607
                     /locus_tag="NLX78_RS25135"
                     /old_locus_tag="NLX78_25125"
     CDS             20001..>27607
                     /NRPS_PKS="Domain: Condensation_Starter (7-298). E-value:
                     2e-76. Score: 249.1. Matches aSDomain:
                     nrpspksdomains_NLX78_RS25135_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (464-861). E-value:
                     1.8e-122. Score: 400.8. Matches aSDomain:
                     nrpspksdomains_NLX78_RS25135_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (968-1035). E-value: 1.7e-25. Score:
                     81.0. Matches aSDomain: nrpspksdomains_NLX78_RS25135_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1046-1356). E-value:
                     4.2e-153. Score: 502.9. Matches aSDomain:
                     nrpspksdomains_NLX78_RS25135_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1360-1512). E-value: 1e-48.
                     Score: 157.1. Matches aSDomain:
                     nrpspksdomains_NLX78_RS25135_TIGR01720.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1522-1822). E-value:
                     5.2e-109. Score: 355.9. Matches aSDomain:
                     nrpspksdomains_NLX78_RS25135_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1993-2452). E-value:
                     4.8e-114. Score: 373.1. Matches aSDomain:
                     nrpspksdomains_NLX78_RS25135_AMP-binding.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371211.1"
                     /locus_tag="NLX78_RS25135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_25125"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_254351828.1"
                     /sec_met_domain="AMP-binding (E-value: 5.5e-127, bitscore:
                     415.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.4e-12, bitscore:
                     37.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 7.7e-77, bitscore:
                     250.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQHNVQLYALSQPQQRIWYTELVYPNRNTSTIITTVKIKGTVRI
                     DALQQAMNQVIAQNDSFRIKITARDGIPYQYVEPFAAQSIETLQVTPEEAELWVSHHNA
                     QPFPLLDSQLYRFVILRLGAEDTWFSFKMHHIISDGVTMEQAINEITGHYMNIVHGTGS
                     DALAPANSYLDFIQVEQSYEQSDRYQKDKTYWTEKFANLPEVTGLKSYNPLTVSTAARR
                     ENYTLEHELYRGVTAFCEANNISIFTFFLAALYIYLHKMTGEQDLTVGTLYANRTLKKE
                     KNTMGMFVSTVATRLRVEPESELLTFLQGVGKEQSSILRHQRYPYNKIMQDLREQQSGT
                     DIRRLFGVTIQYRTLSFSRFDEAVQQVHTDFCGDTVSDFDIAMIDMLDDDKLVLQLDYR
                     TELFSEQEIARIIRQFLSVVEHMVKGPQKRIQELSLMSDEERAQIMDVFNATAVPYPHN
                     VGIHELFEEQAKRTPDQTAVMFGNQCLTYRELNERANSLARMLQAQGVGPDKLVGLMVQ
                     RSLEMIVGLLAVLKAGGAYVPIDPEFPSSRIEYMLEDSKAEVLLTSRDLAEEHHYIANT
                     MFLEDAALYQGESGNLEAFARPEHLAYVIYTSGSTGNPKGVMLQHRSVLNFITGMREII
                     DFEANKTILSLTTISFDIFVLETILPLLSGMTVVLGDRQHQVNPQALGELIAHHHIDML
                     QMTPSRLQMLMDHEAGFRALRDVKEIMVGGEALPSKLLAALQEINGPRIYNMYGPTETT
                     VWSTVQELTHAQDINIGRPIANTQIYIMNASGELQPVGVPGELCIAGEGLARGYWNREE
                     LTAEKFVDNPFAGGKVGYERMYRTGDLARWTLDGNIEYLGRMDHQVKIRGYRIELGETE
                     SQLLQVESVREAVVVAHTDETGQKQLVAYYVACQELGASELRSELGRELPSYMVPSYFI
                     QLEQMPLTPNGKIDRKSLPAPEGSLQSGADYVEPRTATERALAAVWQSVLGVPTVGMLD
                     NFFDLGGDSIKAIQIVSRAFQAGYKLDMKDLLRYPTVAALAPHMHEASHMADQGEVSGE
                     TALLPIQHGFFEQEQVDAHHFNQAVMLHREQGFDEAALGQALIKLTEHHDALRMVFRKT
                     EQGFQAWNRGIQEGELYHLDVLDFRALTDKSMLSATIETKATEIQNNINLSEGPLVKLG
                     LFRCTDGDHLLVAIHHLVVDGVSWRILLEDLATGYEQSLRGESVRLPNKTDSFRLWADQ
                     LSTYANSSALEKERAYWEQIEQAGKSQASLPKDYTRKSQAKPQLRDDRTLTVAWTVEET
                     EQFLKQAHQAYNTEANDLLLTALGTAIQEWAGIHQVLVNLEGHGREAILPDVDITRTIG
                     WFTSQFPVVLDMGEEQNVGRRVKNVKEGLRRLPHKGIGYGILRYLADGEGEAPFITEPE
                     ISFNYLGQFDQDLKNNAFRMSPYSIGASMSDTLTKRYALDINGMITDGALELTISYSRK
                     TFMKKSIQRLAGLLQESFREVLAHCVEKELPELTPSDLSFQGLTAGELDHIVEQTAAAG
                     ELENIYSLTPMQKGILFHGLMEPKSGAYFEQATFDLQGSFQVEAFAESLNQLVDRHQIF
                     RTNFYSGWNEQPLQVVYRHKHAGFRFEDVRSMGQGEQDAYIAGFAEHDKAEGFNFGSGE
                     LMRVSVLRTGEESYRFVWSFHHILMDGWCLFLIVGEAFNTYFAILEDRKPELAPVTPYS
                     EYIEWLERQDKAEAERFWSDYFAGFEQQTVLPQAKQLDGHAKGYEGDKLSFTLSREVTK
                     QMNKLVKQQQVTVNTLLQAAWGVVLQRYNNSRDVVFGSVVSGRSADIPGIDTMVGLFIN
                     TVPVRIHSPKDVTFAELMKQTQEQALASRAYETYPLYEIQALTEQKQDLVNHIMVFENY
                     PVEQRMEHMGSRDTNGFTIANASMSEQTNYDFNITVVPGDEMDIHLEFNALVFERAAVE
                     QFREHWLRVIEEAIHKPHALVDELELVTAEEKVKIIDGFGSVGVSAWSDEKQSEGLFHA
                     YVEEQAQLVPDHVAVVYEERQLTYRELNERGNQLARRLRNEGIGRESIVGILSERSVDM
                     LVGVLAVWKAGGAYVPLDADYPSERIRFMLEDSGATVLLTQTGLQERAQAWLEESRQAL
                     AGGQSEGELETAVSIETMERDSLNEGFSLKSDSSSDSEAASESAANLRLHTVLALDDES
                     LYIGDATDVEPINEPQDLAYVIYTSGTTGRPKGVMIEHHSLVNTAAAYRRDYRLNQFPV
                     RLLQLASFSFDVFVGDIARALYNGGTMVICPKDDRIDPSRLYGWIHDYQITVFESTPAL
                     IVPFMQHVHEQGLDMSSLELLITSSDSCSVTDYRVLQERFGADVRIMNSYGVTEAAIDS
                     SFYDEELSKLPSSGNVPIGQAWLNARFYILDSQLNPVPIGVLGELCIGGAGVARGYLNR
                     ADLTAEKFVANPYVPGERLYRTGDLARWMPDGNVDFIGRMDYQVKIRGYRIELGEIETA
                     IQRVPGVRQAVVIDRTDERGHKYLCGYITGEDELRIEEVQAELEAGLPAHMVPARLMRL
                     ETIPLTSNGKIDR"
     aSDomain        20022..20894
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NLX78_RS25135_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="2.00E-76"
                     /label="NLX78_RS25135_Condensation_Starter.1"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="298"
                     /protein_start="7"
                     /score="249.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="LYALSQPQQRIWYTELVYPNRNTSTIITTVKIKGTVRIDALQQAM
                     NQVIAQNDSFRIKITARDGIPYQYVEPFAAQSIETLQVTPEEAELWVSHHNAQPFPLLD
                     SQLYRFVILRLGAEDTWFSFKMHHIISDGVTMEQAINEITGHYMNIVHGTGSDALAPAN
                     SYLDFIQVEQSYEQSDRYQKDKTYWTEKFANLPEVTGLKSYNPLTVSTAARRENYTLEH
                     ELYRGVTAFCEANNISIFTFFLAALYIYLHKMTGEQDLTVGTLYANRTLKKEKNTMGMF
                     VSTVATRLRV"
     aSModule        20022..24536
                     /complete
                     /domains="nrpspksdomains_NLX78_RS25135_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_NLX78_RS25135_AMP-binding.1"
                     /domains="nrpspksdomains_NLX78_RS25135_PCP.1"
                     /domains="nrpspksdomains_NLX78_RS25135_Epimerization.1"
                     /domains="nrpspksdomains_NLX78_RS25135_TIGR01720.1"
                     /locus_tags="NLX78_RS25135"
                     /monomer_pairings="Gly -> D-Gly"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20109..20198
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0001"
                     /evalue="3.10E-07"
                     /label="C2_starter_024-063"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="66"
                     /protein_start="36"
                     /score="23.1"
                     /tool="antismash"
                     /translation="VKIKGTVRIDALQQAMNQVIAQNDSFRIKI"
     CDS_motif       20397..20462
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0002"
                     /evalue="1.20E-04"
                     /label="C3_dual_135-156"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="154"
                     /protein_start="132"
                     /score="15.1"
                     /tool="antismash"
                     /translation="MHHIISDGVTMEQAINEITGHY"
     CDS_motif       20796..20885
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0003"
                     /evalue="6.00E-07"
                     /label="C5_LCL_267-296"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="295"
                     /protein_start="265"
                     /score="22.0"
                     /tool="antismash"
                     /translation="DLTVGTLYANRTLKKEKNTMGMFVSTVATR"
     CDS_motif       20937..21056
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0004"
                     /evalue="2.60E-09"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="352"
                     /protein_start="312"
                     /score="29.6"
                     /tool="antismash"
                     /translation="KEQSSILRHQRYPYNKIMQDLREQQSGTDIRRLFGVTIQY"
     aSDomain        21393..22583
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NLX78_RS25135_AMP-binding.1"
                     /evalue="1.80E-122"
                     /label="NLX78_RS25135_AMP-binding.1"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="861"
                     /protein_start="464"
                     /score="400.8"
                     /specificity="substrate consensus: Gly"
                     /tool="antismash"
                     /translation="FEEQAKRTPDQTAVMFGNQCLTYRELNERANSLARMLQAQGVGPD
                     KLVGLMVQRSLEMIVGLLAVLKAGGAYVPIDPEFPSSRIEYMLEDSKAEVLLTSRDLAE
                     EHHYIANTMFLEDAALYQGESGNLEAFARPEHLAYVIYTSGSTGNPKGVMLQHRSVLNF
                     ITGMREIIDFEANKTILSLTTISFDIFVLETILPLLSGMTVVLGDRQHQVNPQALGELI
                     AHHHIDMLQMTPSRLQMLMDHEAGFRALRDVKEIMVGGEALPSKLLAALQEINGPRIYN
                     MYGPTETTVWSTVQELTHAQDINIGRPIANTQIYIMNASGELQPVGVPGELCIAGEGLA
                     RGYWNREELTAEKFVDNPFAGGKVGYERMYRTGDLARWTLDGNIEYLGRMDHQVKIR"
     CDS_motif       21579..21620
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0005"
                     /evalue="6.90E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="540"
                     /protein_start="526"
                     /score="19.1"
                     /tool="antismash"
                     /translation="LAVLKAGGAYVPID"
     CDS_motif       21804..21863
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0006"
                     /evalue="2.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="621"
                     /protein_start="601"
                     /score="32.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGNPKGVMLQH"
     CDS_motif       22365..22454
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0007"
                     /evalue="5.90E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="818"
                     /protein_start="788"
                     /score="56.9"
                     /tool="antismash"
                     /translation="PVGVPGELCIAGEGLARGYWNREELTAEKF"
     CDS_motif       22548..22613
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0008"
                     /evalue="1.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="871"
                     /protein_start="849"
                     /score="36.6"
                     /tool="antismash"
                     /translation="YLGRMDHQVKIRGYRIELGETE"
     aSDomain        22905..23105
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NLX78_RS25135_PCP.1"
                     /evalue="1.70E-25"
                     /label="NLX78_RS25135_PCP.1"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1035"
                     /protein_start="968"
                     /score="81.0"
                     /tool="antismash"
                     /translation="ERALAAVWQSVLGVPTVGMLDNFFDLGGDSIKAIQIVSRAFQAGY
                     KLDMKDLLRYPTVAALAPHMHE"
     aSDomain        23139..24068
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NLX78_RS25135_Epimerization.1"
                     /evalue="4.20E-153"
                     /label="NLX78_RS25135_Epimerization.1"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1356"
                     /protein_start="1046"
                     /score="502.9"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDG"
                     /tool="antismash"
                     /translation="GETALLPIQHGFFEQEQVDAHHFNQAVMLHREQGFDEAALGQALI
                     KLTEHHDALRMVFRKTEQGFQAWNRGIQEGELYHLDVLDFRALTDKSMLSATIETKATE
                     IQNNINLSEGPLVKLGLFRCTDGDHLLVAIHHLVVDGVSWRILLEDLATGYEQSLRGES
                     VRLPNKTDSFRLWADQLSTYANSSALEKERAYWEQIEQAGKSQASLPKDYTRKSQAKPQ
                     LRDDRTLTVAWTVEETEQFLKQAHQAYNTEANDLLLTALGTAIQEWAGIHQVLVNLEGH
                     GREAILPDVDITRTIGWFTSQFPVVLDMG"
     CDS_motif       23241..23315
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0009"
                     /evalue="3.90E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1105"
                     /protein_start="1080"
                     /score="16.1"
                     /tool="antismash"
                     /translation="FDEAALGQALIKLTEHHDALRMVFR"
     CDS_motif       23352..23375
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0010"
                     /evalue="1.60E+01"
                     /label="C1_dual_004-017"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1125"
                     /protein_start="1117"
                     /score="-0.5"
                     /tool="antismash"
                     /translation="IQEGELYH"
     CDS_motif       23526..23591
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0011"
                     /evalue="1.80E-11"
                     /label="NRPS-E2"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1197"
                     /protein_start="1175"
                     /score="36.2"
                     /tool="antismash"
                     /translation="LLVAIHHLVVDGVSWRILLEDL"
     CDS_motif       24009..24059
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0012"
                     /evalue="2.40E-07"
                     /label="NRPS-E5"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1353"
                     /protein_start="1336"
                     /score="23.0"
                     /tool="antismash"
                     /translation="DITRTIGWFTSQFPVVL"
     aSDomain        24081..24536
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NLX78_RS25135_TIGR01720.1"
                     /evalue="1.00E-48"
                     /label="NLX78_RS25135_TIGR01720.1"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1512"
                     /protein_start="1360"
                     /score="157.1"
                     /tool="antismash"
                     /translation="VGRRVKNVKEGLRRLPHKGIGYGILRYLADGEGEAPFITEPEISF
                     NYLGQFDQDLKNNAFRMSPYSIGASMSDTLTKRYALDINGMITDGALELTISYSRKTFM
                     KKSIQRLAGLLQESFREVLAHCVEKELPELTPSDLSFQGLTAGELDHI"
     CDS_motif       24102..24164
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0013"
                     /evalue="3.00E-10"
                     /label="NRPS-E6"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1388"
                     /protein_start="1367"
                     /score="32.2"
                     /tool="antismash"
                     /translation="VKEGLRRLPHKGIGYGILRYL"
     CDS_motif       24219..24272
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0014"
                     /evalue="5.40E+00"
                     /label="NRPS-A_a8"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1424"
                     /protein_start="1406"
                     /score="0.4"
                     /tool="antismash"
                     /translation="YLGQFDQDLKNNAFRMSP"
     aSDomain        24567..25466
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NLX78_RS25135_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="5.20E-109"
                     /label="NLX78_RS25135_Condensation_DCL.1"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1822"
                     /protein_start="1522"
                     /score="355.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILMDG"
                     /tool="antismash"
                     /translation="ENIYSLTPMQKGILFHGLMEPKSGAYFEQATFDLQGSFQVEAFAE
                     SLNQLVDRHQIFRTNFYSGWNEQPLQVVYRHKHAGFRFEDVRSMGQGEQDAYIAGFAEH
                     DKAEGFNFGSGELMRVSVLRTGEESYRFVWSFHHILMDGWCLFLIVGEAFNTYFAILED
                     RKPELAPVTPYSEYIEWLERQDKAEAERFWSDYFAGFEQQTVLPQAKQLDGHAKGYEGD
                     KLSFTLSREVTKQMNKLVKQQQVTVNTLLQAAWGVVLQRYNNSRDVVFGSVVSGRSADI
                     PGIDTMVGLFINTVPVRIH"
     aSModule        24567..27356
                     /domains="nrpspksdomains_NLX78_RS25135_Condensation_DCL.1"
                     /domains="nrpspksdomains_NLX78_RS25135_AMP-binding.2"
                     /incomplete
                     /locus_tags="NLX78_RS25135"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       24576..24614
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0015"
                     /evalue="5.10E-04"
                     /label="C1_dual_004-017"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1538"
                     /protein_start="1525"
                     /score="13.0"
                     /tool="antismash"
                     /translation="YSLTPMQKGILFH"
     CDS_motif       24636..24749
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0016"
                     /evalue="2.20E-16"
                     /label="C2_DCL_024-062"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1583"
                     /protein_start="1545"
                     /score="52.1"
                     /tool="antismash"
                     /translation="GAYFEQATFDLQGSFQVEAFAESLNQLVDRHQIFRTNF"
     CDS_motif       24972..25037
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0017"
                     /evalue="2.70E-08"
                     /label="C3_DCL_135-156"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1679"
                     /protein_start="1657"
                     /score="26.3"
                     /tool="antismash"
                     /translation="FHHILMDGWCLFLIVGEAFNTY"
     CDS_motif       25083..25121
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0018"
                     /evalue="5.50E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1707"
                     /protein_start="1694"
                     /score="9.6"
                     /tool="antismash"
                     /translation="PYSEYIEWLERQD"
     CDS_motif       25365..25460
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0019"
                     /evalue="1.60E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1820"
                     /protein_start="1788"
                     /score="62.3"
                     /tool="antismash"
                     /translation="DVVFGSVVSGRSADIPGIDTMVGLFINTVPVR"
     CDS_motif       25509..25625
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0020"
                     /evalue="7.20E-17"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="1875"
                     /protein_start="1836"
                     /score="53.8"
                     /tool="antismash"
                     /translation="QEQALASRAYETYPLYEIQALTEQKQDLVNHIMVFENYP"
     aSDomain        25980..27356
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NLX78_RS25135_AMP-binding.2"
                     /evalue="4.80E-114"
                     /label="NLX78_RS25135_AMP-binding.2"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="2452"
                     /protein_start="1993"
                     /score="373.1"
                     /specificity="substrate consensus: Dab"
                     /tool="antismash"
                     /translation="VEEQAQLVPDHVAVVYEERQLTYRELNERGNQLARRLRNEGIGRE
                     SIVGILSERSVDMLVGVLAVWKAGGAYVPLDADYPSERIRFMLEDSGATVLLTQTGLQE
                     RAQAWLEESRQALAGGQSEGELETAVSIETMERDSLNEGFSLKSDSSSDSEAASESAAN
                     LRLHTVLALDDESLYIGDATDVEPINEPQDLAYVIYTSGTTGRPKGVMIEHHSLVNTAA
                     AYRRDYRLNQFPVRLLQLASFSFDVFVGDIARALYNGGTMVICPKDDRIDPSRLYGWIH
                     DYQITVFESTPALIVPFMQHVHEQGLDMSSLELLITSSDSCSVTDYRVLQERFGADVRI
                     MNSYGVTEAAIDSSFYDEELSKLPSSGNVPIGQAWLNARFYILDSQLNPVPIGVLGELC
                     IGGAGVARGYLNRADLTAEKFVANPYVPGERLYRTGDLARWMPDGNVDFIGRMDYQVKI
                     R"
     CDS_motif       26166..26207
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0021"
                     /evalue="4.20E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="2069"
                     /protein_start="2055"
                     /score="19.7"
                     /tool="antismash"
                     /translation="LAVWKAGGAYVPLD"
     CDS_motif       26562..26621
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0022"
                     /evalue="5.00E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="2207"
                     /protein_start="2187"
                     /score="34.3"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGRPKGVMIEH"
     CDS_motif       27150..27239
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0023"
                     /evalue="1.70E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="2413"
                     /protein_start="2383"
                     /score="55.4"
                     /tool="antismash"
                     /translation="PIGVLGELCIGGAGVARGYLNRADLTAEKF"
     CDS_motif       27321..27386
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NLX78_RS25135_0024"
                     /evalue="1.40E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="NLX78_RS25135"
                     /protein_end="2462"
                     /protein_start="2440"
                     /score="36.3"
                     /tool="antismash"
                     /translation="FIGRMDYQVKIRGYRIELGEIE"
ORIGIN
        1 tagggggaac ttgaggatat tctttccgat tcaccagacc atccgcttcc aattctttta
       61 gttgtgaact caatgtttta taagtaatag cccctatctg tcttttcaga tcattaaagc
      121 gaactgttcg gttttcggct aggagataaa taataaccat tttccattta ccaccaatca
      181 gtgaaactgt ataaccaaaa ggtgtatctt gaatgttttt aactttacct ttaaattcag
      241 ccatactcat gtttacaata tcctttcggg tagtacctat caaaatagtg cgtactacgt
      301 ttttatttgt gttcagttta tactaacctt acttttgaag taaaggagag aaaaacatga
      361 ctgaaaaaac aatacgtctg ttaatgccac aatggcaagg gggaaacaat cctaattact
      421 cttttggagc cgaactgctt gcttggctag ctccggataa tgatcaaccc cttattcatg
      481 ttcccattca agcttataac ggtactccgc ttgaaaacga aaacggtatg aatgggagaa
      541 aacagctact tgaacagtta gaggctgctc agcatatcat tgatgctcat aagccagatc
      601 gtattgtaat gtttggtggt gactgcttag tggaacaagc tccatttgcc tatttgaacg
      661 aacgatacgg tggggaatta ggtttaattt ggatcgatgc tcacagtgat ttagttagat
      721 atgtgggcta tgataacgga catacattac cgctcggaaa tcttttggga gaaggagatg
      781 aggagttcgc aaaacatgtg aaaatcccac taaaacctga aaatgtcttt atcgcgggat
      841 tagcggctcc tacagaacaa gaaacagaag ccatttcaga agcgtttcaa agactaggta
      901 tagctcctgc agaatcagac acagaagtga ttcaaagact agggattaaa actgcaggaa
      961 ccaaagagtt aacgaatagt actgaatcta ttagagagtg gattaaagaa agtggcatta
     1021 agcatctagc tattcacctt gatttagatg tgcttgaccc aaaagcattt cgttctttac
     1081 tgttcgccaa ccctgaagcg ccctataatt tttctcctgc gggaacaatg caaatgcctc
     1141 agctacttaa tctgattaaa gaactatctg aagaaacaga tgtagttgga ttaggtataa
     1201 cagagcatat gccgtgggat gctattaatt taaagaatct gcttggagag atacctattt
     1261 taaataagta agttcataca tggattataa tagaacaatg atctgcttaa tcacaaaaat
     1321 acacccccgc aaacataaag tgcgtgagtg catttttatg attaagcgat tttgacatcc
     1381 tatatttggg attgtgatat gtaggagaaa attcaacgaa tttagtttta tgaatgaaca
     1441 gagctgagaa atgacaactt aagaaagtag tatacatcac aatttccaaa ggaggatatc
     1501 tgttatggct caccagaaga aaaggaaaga agcagcctgg aagtcacgaa agcaagagca
     1561 gcatccccat ggtaaagtca aatcgctcaa ggagctgtcc agcgaatagg agtgatgagt
     1621 atactgcttg aaagagaagg actgtcggtg aaattcatcg gcagccctct ttttgcaata
     1681 atttcgctta tagacaaccc aatgcagata gcgggacttg taaaaaatgt tttcctgatg
     1741 acagcgtcta caaacaccaa attgctatgc gtcacataca tcttcactta ttttggacca
     1801 gtaatttaca gcgttctact atagagggta tcttcttaaa ttcgtttttc taaaggctgc
     1861 ctgttccggc taagaaatga agcatctcct gtccaggaga tgctcaggct gtcgagaaac
     1921 cccctgtttt tttgcagggg gtttaaaact gtcttagtgg tctaaaaact agggtcctca
     1981 gatcgtttta aatcgatttt tgttttaaaa gatgcgtctc cccatataaa aatagaattg
     2041 tcgaaaagtc ctctggactt tctcgacact ctgagcatct cctgtccagg agatgcttct
     2101 tctacgttat gattggggag tctgagataa gctgatttat caggatatga ttgaattcag
     2161 gagaccctgc ttcacctgat ccgacagggg cataagtggc agacgcaatt gctcggcggc
     2221 aataatctct tgttgggtaa gccaccactt gatcgcggcc ggggctggct ctgcaaatac
     2281 atgctggatc atcggttcta gtagcataaa actgtctcgc gacccgttca tgtcgccagc
     2341 cacaaaacgt tggtatatat ccacatactt ctggatatgg agatgagcgg atgcaagcat
     2401 accaccggta gccccctggc atagcatggc atggaaatag gcatcctctc cgcagaggac
     2461 aggcttggtc tcgtactggg ccaattttaa gagcagatca agaccgcccg tgctgtcctt
     2521 gagcccaatt atgccatcca ggtccagcac tttgcgaatt gtatctattg tcatgcgact
     2581 acccgtgcga accggaatct catatactag cacaggcagg cctacacgag atacgacacg
     2641 gaaatgctcc aatattcctt cctgcgtcgg ccggttgtaa tacggagtga ccaccatggc
     2701 tgcatccgct cctaattcag ccgccatttc cgtccgatgc accgttgaat aggtatcatt
     2761 cgttcccgtg ccaataacga tcggaatggt tttgttcatg atcttcagaa catcctgcgt
     2821 cacatgtacc atcagcttca cttcatccca ggatacggtt ggcgactctc ctgtcgtacc
     2881 gttaacgacc agaccctgga tgtcatggcc tgcaagatag gtaacatact tccggtacga
     2941 atcgatgtcc agcttatagt cacgcgtaaa aggtgtaatc agcggtatga aaatcccatg
     3001 aatatgttgt tcgttcatca tcatcagtta tcccttcccg ttgaattaaa tctaatgtaa
     3061 cataggaaac agcatcagag ttatctataa taaacgatga ttctaatcaa aattttcgat
     3121 ggggtggcca gattggattt catttatctt caaacatttc gggaagttgc cattcgtgaa
     3181 agctttacaa gagcagcaga agtgctcggt tacgcacaat ccagcgtcac gacccagatt
     3241 caaaagctgg agaaaacata tcaagttaaa ttgttcgagc gctacaataa caataagatt
     3301 cgtcttacct ccgccggaga agagctgttc aagcttgctg gacaaatgct ggagcttttc
     3361 gagcaatcga aagaaaaatt ggccaagcag ggcggaggct ccatgacgat cggtactatg
     3421 gattccatcg cttcgtattt tctgccgccg tatatgcagg cgactcgcaa agaataccca
     3481 gatctgaaca tacgattgca tacggatcgc gaagagatga ttttgcacca ggtgagggaa
     3541 ggggaggccg atgttgggtt gatcctcgcg gacgattcaa gcaatccggc gttgcagtgg
     3601 attaccattc gagaagaacc gcttgtgctg attgtccatc cgaaccatcc gcttatcgct
     3661 aaagagcaaa tcgacctgaa tgatctggtt gatgcggagt ggatcatgcc cgagcatacg
     3721 tgcaactaca gacaactgct ggagagagtg cttcgagcaa atggaatcac ctatcgcgtg
     3781 agtctggagc tgggtaatcc ggaagcgatc aaacggagca tcaagactgg agagggtata
     3841 tccattctac ctctaatggc tgcgctggaa gagattgaac gggaagagtt aaaggtgtta
     3901 ccctttgagc atgccgagct caagctggaa attcagcttg ttcttcatcc caaaaagtgg
     3961 gtgtccaacg cattgagctt ttttatggag agcatgagaa tatagatttt cctccacatc
     4021 aaaattaata tacaatacga gcgcttccta gtagatacca gaagcgctca aagtttaacg
     4081 taccgaagaa tgagaactta gaaagcaaag atgaaccaaa gtttattcaa atcatcgacg
     4141 tattttttct ggagaataag caatcaatat ttgtattcac taaaccattc ggttacttaa
     4201 tgtttaatta gaacaagatg atcgacctta cagccaagaa aggtgattta agttaatggg
     4261 aaaggaaaaa atataataat gaggagtgat taggtgaagg ttttggtggt aggttcaaat
     4321 ggacaaattg gacaacatct tatccatttt ttgaaagaaa acaaagaaca cacagtccgt
     4381 gcgatggtta ggaaacaaga acaagctaat gcttatcata atggttccat gttcctgatg
     4441 ttttggtttt taggcaaggg catattccat tactttatca aataaaactg gagcccaaag
     4501 aagaacgaaa caatgatcga acagaattgg gtaataaata ttgtagaaca tgcgcatcaa
     4561 aaaaggattg gaaatatcaa gtagttttcc caaaaacacc tccgatatct ctgtcccgta
     4621 accttaagtt tttgaaaggt tttttaaaag agagaaagta ctattcacaa tggtataacc
     4681 ctgttatcta tcgacttcag tgtatttggg tcttgtccag ttgaccatct tgcctccaca
     4741 ttcgtaaaca atacagatcc cctcttaatt aaaccattga tttatcacct catcgcaaaa
     4801 ggaacattaa tcaccaatct caacgagctt atttcatccc gtagcataat atcactaaac
     4861 acacaggtga acccccaagt agaaaaaata gatggaggaa tgttgtatgc atttaaccaa
     4921 atcaggatat atgcttagta ttgtctttat gggaaaaagt tcaaggtggt taccataaat
     4981 ccccctcatg tgtggctaag gaggcctgat ggtgaggatc tagagatatt ttttactgat
     5041 ttagtgaatc acccgacttt tgtaccggaa gcctcgatga aacttgagaa gcaacaagag
     5101 aagaagtcat acgataatgt acttgcaaaa ttagatccga aaaaaagaga cgaggtcagt
     5161 aaacgttttg atctgataca gccgctgatt ttactcgaaa agataaagaa tggtaatatt
     5221 caagccgtgt caaaatttaa tgataaatat aaggaacttc ttcatgagga tgaagaagtg
     5281 tttaaactta agcaagaaga gttaatctct aaaattgtga aaaagtttgg cggatccagg
     5341 gcaaccatta tgcgcatttt ggcaaattat agaaaatacg aagacgcatc gatatccaga
     5401 ggacttgaga gattaatatc aaataaagga aaaggataca caggaagaaa agataacaaa
     5461 gtgatgacaa tttgccatcc agaacggcaa gaaattgtac tggatactat tcttgtccgt
     5521 cttactgata agcaaattga aatattaaaa gaaaatcttg aaagggacta cctaaataaa
     5581 tatcgtgtat cgaaagcaac aatacataga ttagtagaac gaagatgcgc gaaggtgaac
     5641 gaagcagaag ttaaatatag cacaatctcc gatattattg accgaattga taaacaggca
     5701 gtagaaagac ttcgaaatat aaataaggct aagactattt atgatgaagt cgcccgtggc
     5761 tatgcaaaca gagaggccat atataggttg gatattattc agatggatca tacacgcttg
     5821 gatatgcagg tgattgatga tgtaacaggt cttgtaatta agcctgctgc tacgaagcct
     5881 acaggaagta gacgaaagag cgctgctgat gataagaaga ccgaataagg agagcgtgcc
     5941 atggaagtcc gatccggaca attcgcatag cagccattgg cagaaaaaaa gggttgtccc
     6001 ataagtcata aaaatgacta gggacgtcct gttctccaat tgtaaaacaa taagaaaccg
     6061 ttcctgggta aaatggaggt gccacccgac catttgaaag gatatggttt ctttgtacat
     6121 tcaatatacc attatgagat aaaaagaggg gttacgcagg actatctctc atccatgtta
     6181 tgtggctttg tggccagccc ctcatttaat gtctattagc tcttaaacct tcaataaata
     6241 tgcggtgtaa tccatcaaga actcgttggc ttgtaaagcc ttcatcttgg agatggtaat
     6301 cgatattgtg aagcacggcc agcagggctt caatagtata tgaaatgtcc accccggata
     6361 cgtctccctg ttcaacggcc tcatttagca gatttctgct tatattgcgc atccattgac
     6421 ataacggaga ttgtaacgga cgatgcccgg ttgaggcccg gctgacctca cagagccaag
     6481 gaactttcgc ttctaaaaaa gatacatatc ttacgattac atggtaaagc cggtccaagg
     6541 cagcggtttc tggggactga tcaagaaatg cttgaacttc atcaaacaaa ggttggtatt
     6601 cttcatacgc gatctcctga catatgtcgc ccttatccga gtagcggcgg tataggcttg
     6661 cttgtcctac tccagcagtc ttcgcaatct gatgcatatt gacattgtca acaccgtttt
     6721 tgatgaaaag ttctctagcc gccgccaaaa ttcgtcttcg gtttaactcc tctctgggaa
     6781 ttttcagaga gacagattgc gattctgaat tcatcataaa catctccctt catcattaat
     6841 ttaactgtta tttaacacga aaaacggaca atatgtccgt ttttcgtgta taggacatgt
     6901 tgtccgtctt catattataa tacatttcgt gaaaaattaa aaatacattc atttgggtga
     6961 ccgatgagct tttttttatt tcttggtata gtgctttttg taaattggag gcaaatgcgg
     7021 ttcaatgccc gataggtcca gttcctttaa acttgcgatc gtatgaataa actgctcgta
     7081 tgcttttttc ttgtcgctcg tcgtatctgt tccggtttcg gttgatgctt tcctgctaac
     7141 ttcagagtta agttgctttt gatccataga ttaccctcca tcaaatatag tcaggcttac
     7201 aaatccggat gtctcttgtg ccagtctgta ttcatttcat aagtattgcc gatacctagt
     7261 actgtcgctt cttcgaaggg gcggccaatc aattgcatat taatcggcag accggaaggt
     7321 gagaagccgc aaggcatgct caggctaggc aagccagtca aattggtcgg aaccgtaaat
     7381 gagttcaatc tgaatacact agcatcatca tctgcacgcg gcgcagtgat cggtgttgcc
     7441 ggcgtcaaca agatgtcgat tccggacaat gcattcaaaa aatcattgac aattagttgc
     7501 cgggcccgct gagactgaag gtaaatggaa gccggaatat ctctactgct ttcaagaaac
     7561 attcggacgt ccggtccata ctgttccaat tctgtctcaa gccacttctc gtggtacgag
     7621 tacatttccg tcatcataat ggccatcgtc gcacttctaa catgtttgat caggggcagg
     7681 ctaacttcga tgatttctgc tcccagttct cggaatttat tgatagcggc cttcatcgca
     7741 gcttccactt ccggcatcaa atcctcgtaa tagtagcttg tcggcaatcc gatacgcaca
     7801 cccctgagac cattcggata catcttgata cctggcgcag gcagatcgac agtcgattca
     7861 tcctttggat cgaagccaga catcacatcc aagcacaggg acgcatccat gacacagcgg
     7921 gtcaacggac ccgagtggtc caatgaccag gccattggaa tgataccata ccgactgacc
     7981 cgaccgtacg tcggcttcat ccctacgaca ccgcacaaag cagcgggtat gcggatcgaa
     8041 cctccggtat ccgagcctgt gcccagataa gtaagtccag ccgctaaagc agaagccgag
     8101 ccgccgcttg aacctcccgt tacaagttca gtgttccacg gattgaggca aggaccgaag
     8161 tgcgggctag ttgttgtcaa tcccgcagcg aactcgtgag tctgtacttt gcctagcaga
     8221 actgttccag cctcatgtag cttagctgca accgtcgaat cgtaatcggg gacgaagctg
     8281 ttcaatattt ttgaaccggc agttgttcgg atccctttag tgtaatatag atccttatga
     8341 acgatgggaa tcccgtgaag gggccctttg taccgaccat gcataatatc gcgttccgat
     8401 tgcttcgctt gttcaatcgc cagttcggac gtttgggtaa cgaaaacgtt cagtttcgga
     8461 ttcaaacgtt cgatgcggtg aagcgcatgt tctgtaatct ctaccgggga tatttccctt
     8521 gttcggatcc cctcggccag ctcatgaata gcagcaaagg acagttggaa atttaattta
     8581 ctcatctatt catcctccgt ctctttcgga catgtcgtaa gtctaccaaa ctaattacca
     8641 tagcttccgc tacgatttgc ttttcttgcg aataagtatg tcaggattgc caacagggaa
     8701 atggtaaaat aaacaacaga aaaaggcatc tttagatcaa tcagtcggcc gaccagcgca
     8761 gggccgaatg ctccgcctag gagataggcc agtgtgaaaa tacccatccc tacacccagc
     8821 tcagccgaac ggagtgtcgt cgaaactaaa ttgctgctag aggtgaggac accgttgaat
     8881 ccaatcataa ggataatgat caataaagcg tcgatccatg gcggcaaatg tacggatacc
     8941 cccagtagta taaatccgct gatgacgaga ctttgcgata tgacaagcac gcgggagctt
     9001 ccgaaacgat ctgtccaacc tccgatccgg gatccgagca aggctgcaca ggcggcaccg
     9061 ggaagcatca gcagaccgat tttactagtt ggtaaatgaa aggaattctt catcatgaca
     9121 ggaagagtaa aggttaaccc cgtgttgcat acgaaggtaa ggaatccaat ccctagaatt
     9181 cgtcggtaag gagcattttt catgaaagat gcatcgataa atggatgttc ttttttctga
     9241 atatgagtac cgaaccatag aagaactgct gctcctgcaa tgagcataaa ccaatagttc
     9301 gtaaccccta gcaataccaa cgccagtccc gcggagaaca aaacagctcc gagaaaatcg
     9361 aatgaaccgc ggtcgtgttt cttgtcagga acatacttga atatcaaagg gataacaaat
     9421 aggctcagac tggacacgat gaacaaagca cgccagccaa agtattgctc cacgaaaccg
     9481 ccgaacacag gcccgaagcc ggaagcaaag gcaattgtgg cggataaggt tcccagcacc
     9541 cgtcccttga ctgtaggctt aaaatacagg gttactgccg cataagacag gggagagatg
     9601 gatgaggccc ctgctgcctg cagcagtctc ccaatgatga cttgcaagta tgaagctgca
     9661 aaaaagccga tcatagagcc gaaagctaaa aggattaaac caatgacata cagctggcga
     9721 aaggaaaagg actccgttaa cttgccgtaa gtaccggcgc cgatagccat caaaatgctg
     9781 taaccgacca taacccagct cacctgcgag gaggtcaggg caaagtcagc ggaaatcgaa
     9841 ggtatagaca aattaaacat ggtcatattg atgtttccga aaataatgag caagcaaagt
     9901 gtccccatta atttccgctc attgccggat aaagccattg attgagtatc catagcctgt
     9961 ccctccatta caggaagtca ggaaaggtgc ggcatttttg cgcctgatct ctatcgtgtc
    10021 ctaagaaaac ataggacggc cgaacatcct gaattaactc ctgcatgcga gtaatcgatt
    10081 tggcagccat ctcttgatcg aatgtcaaga acggtacgct attctcgaag ttctcccgag
    10141 tataagcaac atcaattgtc agtagcactg gacccgactt ttccgttgtg acaaggactg
    10201 attgatggcc aggggaatga cccggagtga ataaaatttg aacccccgga atcaattcat
    10261 ggtcaccctc aatgatttga tattgtaaat cgggcagcct gcactctaat ggagagtaat
    10321 cctcattgtt tatggccgca tcatactctg ccctttgaat aaggatcggc gtattgcgga
    10381 aatgcccgtt tcccccagaa tgatccaagt gtaaatggga gctaatgacc atttgaatat
    10441 cgtcaggtcg ataacctaca cgctttaaca catttacgat cgagtcgccg tcagacatgt
    10501 tggggacgac gcgcccttca cgtctagtcc ccttgtagta atcgggattg ttgataaaag
    10561 cgtcgggcat tcccgtatcg atgagtatcg gcccgctggt cgtttccaat agaaaagacc
    10621 acacaggcat tccgactaat ttcccggggg caagggttcg attaactgcc gattgatcta
    10681 ggaaacattc acctacaggt aaaaaataca actttttgat attcatccta gtttcaccct
    10741 ttatattata aatccggaca gtttgtccgt tttgttttga ttatatcgga cagattgtcc
    10801 gatgtcaatt tgtcatcggc ggttgggctt cggaatctac tggttctcat ttctcttcac
    10861 agttatagaa tgacgagtga tcatattagg gtgtgattat gttattgttg gaggataagt
    10921 ctcagttata atccaaaaaa aacgtaaaaa gtctcagtta taaagcaaga aagtatcact
    10981 tataactaaa aattttagga atgtaagaat aacttttgtc tcaagtatag ccattactca
    11041 tagctggaaa gcagcagttt gaactacaca atcataagac tggggattct tttgaatgaa
    11101 atcggtacgg gaaaagtggc tgccgcggag aatatcacct atggcagtat cccacgtgag
    11161 gatgtagccc gtgccattgt ggcagcttta gatgagggga acacatacaa gcgagcattt
    11221 gatctgatta ctggtgacga ttcagttgtc gaagcattgc aaaaaatctg aagatgagga
    11281 tcaagtgtga atccaaacaa taaagaatta tttgcaccaa ttactttgaa gctttgaaat
    11341 catacctaga gttgacaaat gaaacaaaca tgttaatgta tatgcttgtg catgcatttt
    11401 attgatgcat ttcataatat aaatcagaga ggagtctttc ttacatgaaa gatttattta
    11461 gtccctatac aattaaaggt ttggaattga aaaatcgcgt agttatgcct ccaatgtgcc
    11521 aatattcggt tgacaaaaag gatggggtcg ccacagattg gcattatata cactacgtta
    11581 gccgggcggt aggcggagct ggttttatca taattgaaat gacagatgta gagccagatg
    11641 gtcgtatctc cgattttgat cttggtttat ggtcagatga gcagattcct gctctcaaac
    11701 ggattgtaga tgcttgtcac agctacggtg ccaaagtggg aatccaaatc gcgcatgccg
    11761 gacgcaaggc ggaagatgct gaagtccctg tagcaccatc tgctattgca tttgatgaaa
    11821 attcaaaaca acctcgcgcg cttacaacag aagaggttaa aggactcgtt gaaaaatttc
    11881 gtgctgctgt agctcgcgct gttaaggctg gattcgacag cattgaaatt catggtgcac
    11941 atggctattt gattcatcaa tttcattcgc cgcttacgaa caaacgggaa gatgaatatg
    12001 gtaaagatct tacccttttt ggtcgggaga tcattcaggc agcgaagggc gaaatgccgg
    12061 aagatatgcc gctgttgatg cgtatttctg ccaaagaata tgtagaaggt ggatatggta
    12121 ttaaggaaag cattgctttt gccaaggaat atcaaaaggc aggagtagat atgtttgata
    12181 tttcatctgg cggtgaggga cctatagctg catggggcag accaggaact cacgcagcgt
    12241 atcaagtccc cttggcaaaa gatatcaaag aagctctgga tattccggtg atggccgttg
    12301 gaagactgga agatccaatt ttggcgaatg cagttatcgg taatgaagag gccgatctgg
    12361 ttgctgtggg tagagggatg ttgagaaatc cttattggtc actggaagcc gcatcaaaat
    12421 tgaaaaaaga aactgcaatc cctacacagt atactacagg gttttaagac tgactgtaca
    12481 cattactgat tgagcctgct tgggtcagta aaacgattcg aatcgattaa gcaaaaaaag
    12541 tacgtccttt agaccttctg taaagtactc tatcaaggta ctctacaaaa ggtctaatta
    12601 atgagctctg cgatcacaga gagcatccag aatattgttg ctcaaaccaa tttgctggct
    12661 gcctgggcag gagcatggaa gaaggtttcc gattgtggcg ggagaagtgc gtaagattgc
    12721 cgaatatgct ttgaatctgt gggcggaatc gatgaccaga cgattcatca aagtacggca
    12781 tgtagaactt caccttacaa acaataatga agatgttcag aggaagatac ataagaagag
    12841 attcagtttt agctctgatg tttttacatt ggactttgtg tagaaaaatt ggtaaagata
    12901 caagctagtt acggaggatt tttttgtatt ccatattttc tctaattgac tttgtgactc
    12961 gacattatta ttatcttata ctataagatt aattatctca tactataagg tattagcgag
    13021 aaggtgttgt gaccattgga ttataaatca ttagcgacag aactattcga gtatatcgtc
    13081 aaatcgcgga aaccggcatt agaggaacga gggcacttct cacgtggcga aatggggatt
    13141 ctcatttgtc tgaatttcaa taaggacggg gttacctctg gccacttgag cgaatacttg
    13201 tccgtcagta cgggacgggt agcaacggca ctgaagagtc tggagaagaa agggctagtt
    13261 gtacggcgta ctgatgtcaa cgacaaacgt aaggtgattg tattcattac ggattcaggt
    13321 aagcaattta tgattgatag gcataatgaa ggaattgcat ggaccgagaa tgttcttcga
    13381 aagttagacg aagaggatgc taaagaactg attcgactca ttaagcttat tgtctctaga
    13441 agctgaactt ctatgcagat gcaggacgca ccatacttca ccaaacatca aagactatca
    13501 gataaaagga gagcaacaga atgctaaaga tattcaaata tctcaagaaa aatgaatgga
    13561 tgctcgtact ttgcagccta gctttcatcg ttgtgcaggt atggcttgat ctgaagctgc
    13621 ctgattatat ggcggaaatt acgaccaagc tgcaaacgga aggaacgcct gtgtccgaac
    13681 tgctgattcc cggcagttac atgttgtttt gtgccgtcgg cagtatgatt gcatctatta
    13741 ttgtgggcta tttcgcggca aaggtggctg ctgggctggc tatgcgtctg cgtgcgatgg
    13801 tctttgacaa gaccttatcc ttttctatgg aagagatgaa cagcttttcg acggcaagcc
    13861 tcattacccg ctccacgaac gatgttacgc agattcaaac ggtggttgcg ctggggctgc
    13921 aggtgatcat caaggcacct attctggccg tatgggctat tgtgaagatt gcggataaaa
    13981 actggcagtg gaccgcctcc acaggagcgg ccgtggctgt tctgattcta atgctaagtg
    14041 tcattgttgt tttcgctctt ccaagttttc agagaatcca gcgtctcacc gataatctga
    14101 acagggtaac acgtgagcat ctgatcggac ttcgggtagt acgcgcttat aatgcagatc
    14161 agtatcagca ggagaagttc gagcaggcta acgttgagtt gacgaataca aacctgttcg
    14221 cgaaccgatt aatgacgatg attggcccag gtatgacctt tattatgtca ggtctgagtg
    14281 tctctatcta ttgtatcggc gcttacctga ttaacggggc ggccgtacca gaccgcatca
    14341 cgttgttctc caatatggtt gtattctcct cttatgcaat gcaggtggtt atggccttta
    14401 tgatggtaag tatgatattc attctgatgc ctcgcgcctc gatctctgcc aaacggatca
    14461 tggaggtttt gaataccgaa tccagcatcg ttaacgggca tgagacgact ggagaagaga
    14521 gcgttatggg gcaagtggaa ttccgtaatg tcagcttcaa atatccggac gcggaggagg
    14581 ccgtgcttcg caacattagc tttacggcga aacaaggcga gacggttgcc tttattggcg
    14641 ctacaggcag cggaaaaacc agcgtgatca atctgattcc ccgtttctat gatgtgaccg
    14701 agggagaggt actcgtggat ggtgtgaatg tcagggacta taatcagcag gcactccata
    14761 acaaaatcgg gtatgtcccc cagagagctg tactgttcca cggtacggtt gtatccaacg
    14821 tttcgtatgg cgataacgga agagcaggag cttcggagaa actcgttaaa gaagccgttg
    14881 gtattgctca aggaacggag tttgtcgaaa aaatggatgg tcaatatcag ggtagaattt
    14941 cgcaaggtgg agcgaacgtt tcgggtggtc aaaagcagcg gctgtccatt gcgcgtgcca
    15001 tctaccgtca gccggaaatt tatattttcg atgattcctt ctcggcatta gactacagaa
    15061 cagaccggat tctgcgctcc gctctcaaaa aagaaaccgg ccacgctacg acacttatcg
    15121 ttggtcagcg cataggtact atcaaagacg ctgatcggat tatcgtgctg gaccagggag
    15181 agattgtagg gagcggcacg catgaagagc tgatgacgaa ctgcagcacc tatcaggaaa
    15241 tcgcatattc gcagctttcg aaggaggaac tcatacatgg ataagaatga acacaccgtc
    15301 gacagccagc aaatgaaaat gaatcagcga ggtcccatgg gtaaaggacc cgcggggggc
    15361 aagggtactg gtgaaaaagc gaataatttt aaaaagacca tcagccagct tgtatcctac
    15421 agcaaggcct atgtgcctat gattatacta gctatggtac tggccctggt cggctccacc
    15481 ctcaacgtga ttggccccga taagctcagc gatattgcca acctgattca ggaaggaatc
    15541 gttaccggga ttgatgtaag tgctgttcag aagattgttc ttgtattggc gcttttatat
    15601 ggatttggtc ttatctttaa ctatttccag ggcttcatta cagcaaccgt ctcacagcgt
    15661 cttacaaaga agatgcggac agaactgtct cgaaaaatcg atcatatgcc tttgaagtat
    15721 tttgactcta cgagttacgg taatgtgctt agccgtgtaa ccaacgatgt cgataccatt
    15781 ggacaaacgt taaacaacag tctcggcacg cttgtcagtg cgctggctac cttcgtgggc
    15841 gccttgatta tgatgctgta tacgaactgg atcatgaccg ttaccggaat tatagctacg
    15901 ctgatcggct tttgcctgat gagcgtgatt atgaagcatt cacagaaata ctttgttgca
    15961 cagcaagcgg agcttggcca gatcaacggt catatcgaag aaacttatgc tggtcataac
    16021 gtagtcaagg tatataacgg ggaacaagca gccaaggaag tgtttcatgg cattaacagc
    16081 cgcttatata caaatgcatg gaagtcccaa ttcatgtctg gtctgatgat gccagtcatg
    16141 atgttcattg gaaattttgg ttatgtcgcg gtctgtgtcg tgggagcttt gctggtcaac
    16201 caacagacta taactattgg aactattgtc gccttcatgg tgtatattcg tctgtttaca
    16261 cagcccttgt cgcagctggc acaggccgca accaatctgc agtcggcggc tgccgccagt
    16321 gaacgtgtat tcgaatttct gggtgaagaa gaattggcag atgagcgtca caagaccata
    16381 aagctggaca ctgccaaagg ggatgtcgaa ttcaaacatg tccgtttcgg ctataatgca
    16441 gatcgtatga tcatcaagga cttctccatg aaagctgaag ctggtcagaa aattgccatt
    16501 gtcggtccga caggcgctgg taagaccacg ctcgtgaatt tgctcatgcg gttttatgag
    16561 ctgaacgatg gagaaatcta cattgacggc accccgatta gccaattaac gcgcgaaaat
    16621 attcatgaat tattctgtat ggtgcttcag gatacctggc tgttcgaagg aacgattcgt
    16681 gacaatatcg tcttttccaa agatcatgtt accgatgagc aggtggaagc tgcatgtaga
    16741 gcggtgggtc tgcacagctt cattaaaaca ctgccgcagg gctatgatac agtgctggat
    16801 gacaaagcca atctctctgc cggtcaaaag caattgatta ccattgcaag agccatgatt
    16861 gaagattcac ccatgctcat tctggatgag gccacaagct cggtcgatac gcgtacggaa
    16921 ttgctgattc aacaagcgat ggaccagctg actgtgggga aaacctcctt tgtgattgct
    16981 caccgacttt cgacgatcaa gaatgcggat ctgattctgg tcatgaagga cggtgacatt
    17041 atcgaaatgg gtaaccatga ggaattgttg gctaaaggcg gcttctatgc cgatctatac
    17101 aatagtcagt ttgaacatgc atcttaaaag taaatgcttg aaagcatatt aaatatccat
    17161 ataattccaa cgaaattgac agcagcatgt ggacattata aggtatgaaa gccagaattt
    17221 tttaatcata attgtggagg cagatcaatg aaccagcgtt ttcgaatcac ccgttccatg
    17281 caggaaagtc ctgtggagca atccattacc ctggaggagt gcaaagatta ctttgcatcc
    17341 cagccagact tttcgtattc acgagtacta atcatacaag gtgctgagag caccatgtcg
    17401 atcgagggag actttttcat gtggaagtat gctgatgtag aaataccttt tcgtcattac
    17461 atgggtgatg tgtatgtggc tatttccgat gaggctgtcg tgcctaagat gattgaaatt
    17521 gcaacagatt tgcaagcaga tgtggtggat gggtgaagaa ctattcacta ttcttattct
    17581 gctgaaggta gttgacttcg tagtatatct ttacagcaaa ttgacagtgc tgatttctgc
    17641 ctgctgacat cgagttacat agatgtcagc atttttgtta attatgtcaa tatactggga
    17701 agaataattc ataccacaaa atacatattc cattggcttg atgctaagag acttaacagc
    17761 tggatcaact aaaaggggaa cgatgctagg ttagagatgt ttcgctgttt ctcattacgg
    17821 aggcagtgca agctggtaaa ttagtcgaac aaccattgac ggtaaaaagc ggcgatttaa
    17881 ttattgcttt ggatggcgca ttaatggaga tctccagttc ggaacagttt ggattgtcag
    17941 gatgggctgt cagcgctcgt ttgtatggga tgtttagcga ggaatacagt aatgagattg
    18001 ttttgcgtaa aaaaactgtc ggttaatgtg aacagctgcg gcaagccctt gtcatttaaa
    18061 agacgtgatg tacgagggtt tgtctggatt tctgatgagt ggtttcaaag gattcgtttc
    18121 ctgtctggtc acagggcaga agctcactcg gttgtgatgc gctcggcaac aaaaacgatt
    18181 cgattcgtac acagtataca tcacacaaca aatgtttccg gtacgttcgc tgtgagagta
    18241 ttcacttcat tcttaagggt caagtcgcca aaaccttaaa atagcaagtc tcttgcaaca
    18301 tggagacttg ctattttgta ttttccgttc attaaatttt gcgaaaaaaa tagttccaaa
    18361 gttatgagtt ttctaaaaat ttatattttt aaaggggaat caaaacgttt ctattaatta
    18421 aaaaataaaa tttatagctt aaattagacg gaatttaagc tgaactaaaa tttcaggaga
    18481 aaaattaaag aaaattccgc atgtaaattg gttcaaaaga tctattaaaa gtcactatct
    18541 atttaaaaag tgaagagtta ttaattttga attattccag cttaatgcaa ataaattcca
    18601 tgatataggt aattaaagaa tattgctgaa aaagttgaaa tttgtcggat aatgtcagga
    18661 ttgatttgtt atatttgtgt taatggtatg taacgtaaaa tttgttttgg cacaagggtt
    18721 ttggactttc ttgcaaacct acatcatttt gattttatca atttataaaa tcaaaaattt
    18781 tgttttgaat cacgttaacg ggtcatggtc agtattcaat ttaataaaaa agtaaaattc
    18841 ttgcatttga agatataaaa ataatagaat aatatgggtt atttattgat ttcatgaaat
    18901 ccatcaattt ggaacttatg tcccatgcta atcggtttta aagtttgtat atttaaaata
    18961 gctagaaagt attgggagga aaaaagggat ataaggattt attgtgagat tttggacagt
    19021 aagaggatat gagaaattta tatgtcgact cggtcatgtc ttggttttaa aaccgtgatc
    19081 catctgactg agaaggtcca gttattttgt tttgcccgac atgagggctt tgcctgaatg
    19141 gcttacagaa catgaaagtt gttcaacaga agctccatgg atatcaaaca gaacaacatg
    19201 ccctcacggc ttcccgaaat ggcttcataa gtacataagc tgttttcttt tttagacact
    19261 gtatgggagc actgattgta attgaaacag catggcagtt gtataggcaa aactgcaaga
    19321 ttccctgtcc atagcatcat atctggtaaa tccgtctcac atcattttcc gtattccaaa
    19381 agacagctct attattttta aggtatgcga aatatatcct taacagcctg ggaagcccgt
    19441 tggctcgtcc gatgaccatc atttttcatc catgtacaaa atcaggaagt tataagcgca
    19501 gtcgtgagta tttttttgtc ctttcatcct agaattacgc tcctcaccac gctgcagcag
    19561 ctcatgtatc tcgcagcatc gataccctcc agccaagatt ctaacagcac acatcatgat
    19621 acactacgtt gttaacactg cggcaaccat tctacaaccc accaccaaga tgtactctca
    19681 acataattca aaaatgttct cactccatgc acatattcat acatccagag tcagagttat
    19741 ttcactatgt ccacccaact aaaaaagctt gcactgcgaa agtgtgagtg atgaaaaaga
    19801 gagatgtgct tgtttctatt caaattcagc tcttcgaaga cacccatatc tcaatggtat
    19861 atcaggagtg gtcgcttttg ccgactgcca ttggcaattt aatgccggtg aaaaggtacg
    19921 catgaccagt tccttgacaa ggacggtcat ttatgaggag ttacttttta cccacatcta
    19981 tttcgcgagg agagatacgt atgactcagc acaatgttca attgtatgca ttaagccaac
    20041 cacagcaacg tatttggtac acggagcttg tgtatcccaa tcgcaacacg tccacgatta
    20101 ttaccactgt taaaatcaag ggaacagttc gaatagatgc attgcagcag gcaatgaacc
    20161 aggtgattgc acaaaacgat tcttttcgta tcaaaatcac ggctcgggac ggcatcccct
    20221 atcaatatgt ggagccgttt gctgctcaaa gcatagaaac gcttcaggtt accccggagg
    20281 aagctgagct atgggtcagc catcataacg cacagccgtt ccccttgttg gattcgcagc
    20341 tgtatcggtt tgttattttg cggttggggg cagaagacac ctggtttagt ttcaaaatgc
    20401 accatattat ttcggacggc gtaaccatgg agcaggccat taatgaaatt acggggcatt
    20461 atatgaatat tgtgcatggt acaggttcag atgcgttggc tccagcgaat tcatatctcg
    20521 attttattca ggtggagcaa agctatgagc aatcggaccg ctatcaaaag gacaagacgt
    20581 actggacgga gaaatttgcc aatttgccgg aggttacagg tttaaaatca tacaatccgc
    20641 ttacggtgag tacggctgca cgccgggaga actatacact ggagcacgaa ttatatcgtg
    20701 gtgtcacggc tttttgcgag gcgaataaca tcagtatttt tacatttttc ctggctgctc
    20761 tgtatattta tttgcataaa atgacagggg aacaggattt aaccgtgggt acattgtatg
    20821 ctaaccgtac gttgaagaag gaaaaaaata caatgggcat gttcgtcagc actgtggcta
    20881 cacgtctgcg ggttgagccg gaatccgagc tactcacctt cctgcaaggt gttggcaagg
    20941 agcagtcgtc cattttgcgg catcagcgtt atccgtacaa caaaatcatg caggatttgc
    21001 gtgaacagca aagcggcacg gacattcgcc gcctgtttgg cgttaccatt caataccgta
    21061 cactgagctt ctcccgtttt gatgaagccg ttcagcaggt gcataccgat ttctgcggag
    21121 atacggtgag tgacttcgat attgccatga tagacatgct ggatgacgat aaacttgtat
    21181 tgcaactgga ttatcggacc gagttgttca gcgagcagga gatcgcccga attattcgcc
    21241 aattcctgag tgtggtagaa catatggtga aagggccaca gaagcggatt caggagttgt
    21301 cactgatgag tgacgaagaa cgggcacaaa ttatggatgt atttaatgcg acagcagtgc
    21361 cctatccaca caatgtgggg attcatgagc tattcgagga acaggcaaaa cgtacaccgg
    21421 atcagacagc ggttatgttt ggaaatcagt gtctgaccta tcgggagctg aatgaacggg
    21481 cgaattcatt ggcacgaatg cttcaagcac aaggagtagg acctgacaaa ctggttggtc
    21541 tgatggtgca gcgctcattg gaaatgatcg taggtctgct ggccgtttta aaagcaggtg
    21601 gtgcatatgt gccgatcgat cccgaatttc cgtcatctcg tattgaatac atgctggaag
    21661 acagcaaggc cgaagtgctt ctgaccagtc gtgatctggc agaagaacat cattacatcg
    21721 ccaataccat gtttcttgag gatgcagcat tgtatcaggg agaaagcggc aacctagagg
    21781 cgtttgcccg cccagagcat ctggcttacg tcatctatac ctctggttcg actggaaatc
    21841 cgaaaggagt tatgctccag catcgctcgg tactcaactt tattaccggg atgcgtgaaa
    21901 tcatcgactt tgaagcgaac aaaacgattt tgtcactgac gaccatttca ttcgatattt
    21961 tcgtattgga aaccatcctg cccctgttga gtggaatgac tgttgtgctt ggcgaccgcc
    22021 agcatcaggt gaaccctcag gcgcttggtg agttgattgc tcaccatcat attgatatgt
    22081 tgcaaatgac accatcgcgg ctgcagatgc tgatggatca tgaagcaggt ttccgcgcgc
    22141 tgcgagacgt aaaggaaatt atggtcgggg gtgaagccct tccgtccaag ctgctcgcag
    22201 cactgcaaga aataaacggt ccccgcattt ataacatgta cggacctaca gaaacgacgg
    22261 tttggtcgac cgtacaggaa ctgactcatg ctcaagacat taatatcgga cgtcccatcg
    22321 cgaataccca aatctatatc atgaatgcga gtggggaatt gcagccagtc ggtgtgccgg
    22381 gcgagttatg tattgcaggg gaaggactgg cccgtggata ttggaatcgc gaagaactga
    22441 cggccgagaa atttgtggat aatccgtttg ccggaggcaa agtcgggtat gaacgtatgt
    22501 accgtacagg cgatttggcg agatggacgc tggacggcaa cattgaatat ttgggacgga
    22561 tggaccacca ggtgaaaatc cggggctacc ggatcgaact gggcgagact gaatcgcagc
    22621 tattgcaggt ggaatcggta cgagaagcgg tcgtcgtggc ccatacggac gaaacgggtc
    22681 aaaaacaact cgtggcgtac tatgtggcgt gtcaagaact aggagccagc gaactgagaa
    22741 gtgagctggg gcgggagcta ccaagctata tggtgccgtc gtatttcatt caattggagc
    22801 agatgccgct gacaccgaac ggtaaaattg atcgtaagtc cttgccagca ccggaaggca
    22861 gcctgcaaag cggagcggat tatgtagagc cacgcactgc aacggaacgg gcactcgcag
    22921 ccgtctggca gtccgtcctg ggcgtgccaa ccgtcggaat gttggacaat ttctttgatc
    22981 tgggcggcga ttcgatcaag gcgattcaaa tcgtatctcg tgcgttccag gcaggctaca
    23041 agctggacat gaaggatctg cttcggtacc caaccgttgc agcattggca ccgcacatgc
    23101 acgaggcaag tcatatggca gatcagggag aagtgagcgg ggaaacagcg ttgcttccga
    23161 tccagcacgg gttctttgaa caagagcaag tggatgcgca tcattttaat caggcggtta
    23221 tgctgcaccg ggagcagggc tttgacgaag ctgctttggg tcaggcgctt atcaagctga
    23281 cggagcacca cgatgcactg cggatggtgt tcaggaagac cgagcaaggc tttcaagcgt
    23341 ggaaccgcgg aatacaggaa ggcgagctgt atcatctgga cgtgctggac tttagagctt
    23401 tgacagataa atccatgctg agcgcgacga ttgagacgaa agcaactgaa attcaaaaca
    23461 acataaacct gtccgaagga ccgctggtga aactgggtct gttccgttgc accgatggag
    23521 accatttgtt ggtagcgatc caccatttgg tggtcgacgg cgtgtcttgg cgtattttgc
    23581 tggaagattt ggcaaccggc tatgagcaat ctttacgtgg cgagtctgtc cgtttgccca
    23641 ataagacgga ttccttccgt ctgtgggctg atcagctgtc gacatatgcg aacagttcgg
    23701 ctttggagaa ggagcgtgcg tattgggagc agattgagca agcagggaag agtcaggcat
    23761 ccttgcctaa agattacact cgtaaatctc aggccaagcc acagcttcgc gatgatcgga
    23821 cactgacagt agcgtggacg gtagaagaaa cggaacaatt cttgaagcag gcacaccaag
    23881 cctacaacac ggaagcgaac gacctattgc tgacagctct gggcaccgca attcaggagt
    23941 gggcaggcat ccatcaggtg cttgtaaatc tggagggtca cggacgggaa gccattttgc
    24001 cggatgtgga tattacgcgt acgatcggtt ggtttaccag ccaattcccg gttgtactcg
    24061 atatgggcga ggaacagaat gtgggacggc gtgtcaagaa cgtcaaggaa gggctgcgcc
    24121 gtttgccgca taaaggaatt ggatacggga ttttgagata tcttgctgac ggggaagggg
    24181 aagccccttt tatcaccgag ccggaaatca gctttaacta tctcggacaa ttcgatcagg
    24241 atttgaagaa taatgccttt cgtatgtctc cttattccat cggagcttcc atgagtgaca
    24301 cgttaaccaa gcggtatgct ctggatatca acggcatgat cacggacggt gcactggaac
    24361 tgacgatcag ctacagcagg aaaacattca tgaaaaaatc aattcaaaga ctggctggtc
    24421 tgcttcagga gagcttccgt gaggtattgg ctcactgtgt ggaaaaagag ttgccagagc
    24481 tgacgccaag cgacttgtcc ttccaaggac tgacggctgg agagctggat catattgtag
    24541 agcagacggc tgctgcggga gaactggaaa atatttattc actcacaccc atgcaaaaag
    24601 gcatcctgtt ccacggttta atggagccga aatccggggc gtactttgag caggcgacat
    24661 ttgatctgca aggcagcttt caagtggagg cttttgccga aagcttaaat caactggtgg
    24721 atcgccatca aatattcaga acgaattttt atagcggctg gaatgagcag cctttacagg
    24781 tggtgtaccg tcataaacat gccgggttcc gttttgaaga tgttcgttca atgggacaag
    24841 gagagcagga cgcatacatt gctggttttg ctgagcatga caaagccgaa ggctttaatt
    24901 tcggctcagg cgagctgatg cgggtgtctg ttttgcgtac aggcgaggaa tcgtaccgtt
    24961 ttgtgtggag cttccaccat attttgatgg acggctggtg cttgttccta attgtaggag
    25021 aggcatttaa tacgtacttt gccatcctcg aagaccgcaa gccggagctt gccccggtaa
    25081 cgccatacag tgaatatatt gaatggctgg agcggcagga caaagcagag gctgaacggt
    25141 tctggagtga ctactttgca ggttttgagc agcaaacagt gctgccgcag gcgaagcaac
    25201 tggatggtca cgcgaaggga tatgaagggg ataagctttc gtttaccctg agccgtgaag
    25261 tgaccaagca gatgaacaag ctggtcaagc agcagcaagt gacggttaat acactgctgc
    25321 aagcggcgtg gggcgttgtg ctgcaacggt ataacaacag tcgggatgtt gtatttggca
    25381 gtgtcgtgtc tggtagatca gcggatattc caggcatcga tacaatggtt ggtttgttca
    25441 ttaataccgt tcctgtacgg attcatagtc caaaagatgt aacgtttgct gagctgatga
    25501 agcaaaccca ggagcaggcg ctggcttccc gtgcctatga aacctatccg ttgtatgaaa
    25561 ttcaggccct gactgagcaa aagcaggatc tggtaaatca tattatggtg tttgaaaact
    25621 atccagtgga acagcgtatg gagcacatgg gcagccgtga cacgaacggt tttacgattg
    25681 ccaatgcttc aatgtcagag caaacgaact atgattttaa tattacagtg gtgccaggcg
    25741 atgaaatgga tattcatttg gaattcaacg cgctggtgtt tgaacgtgca gctgtcgagc
    25801 aattccgtga gcactggctg cgtgtgatag aagaagcaat tcacaaaccg catgcgctgg
    25861 tagatgagct ggagctagtg actgctgagg aaaaagtgaa gatcatcgac ggctttggat
    25921 cagtaggcgt atctgcatgg agtgatgaaa agcaatcaga agggttgttc cacgcctatg
    25981 tggaagaaca agcgcagctt gtgccggatc acgtggcagt tgtatacgag gagcggcagc
    26041 ttacgtaccg cgagctgaac gagcgtggga atcaacttgc tcgtagatta cggaatgaag
    26101 gtattgggcg cgaatccatt gttggtattt tgagcgagcg ctcggtggat atgctggttg
    26161 gcgtactggc ggtgtggaag gctggcggtg cttacgtgcc actggatgcg gattatccgt
    26221 ccgaacgtat ccgctttatg ctggaggaca gcggtgcgac agtgctactg acgcaaaccg
    26281 gcttgcagga gcgcgcgcag gcatggctgg aggaaagccg acaggctttg gccggagggc
    26341 agtctgaggg cgagctggaa acggcggtta gcattgaaac gatggaaaga gacagcctta
    26401 atgagggatt cagcttgaaa tcagattcgt catctgatag cgaagcagca tccgaatccg
    26461 cagcgaactt gcgtctgcac accgtactgg cgctggacga tgagtcgctg tacatcgggg
    26521 atgccacgga tgtggaacct atcaatgagc cgcaggatct ggcgtatgtg atctatacgt
    26581 ccggtacaac gggacgcccg aaaggggtca tgatcgagca tcacagtttg gtaaacacag
    26641 ccgcggccta ccgccgggat taccgtttga accagttccc ggtacgattg ctgcaactgg
    26701 caagtttctc cttcgacgtg tttgtcggcg atatcgcgcg ggcgctctat aacggtggca
    26761 cgatggtcat ctgcccgaaa gacgaccgga ttgacccaag ccgtctgtac ggctggattc
    26821 acgactatca gattacggtg ttcgaatcca caccggcttt aatcgtacca ttcatgcagc
    26881 atgtgcatga acagggactg gacatgagca gtctggaact gctgatcacc agctcggata
    26941 gctgcagtgt gacagactac cgggtgctgc aagaacggtt tggcgcggat gttcgtatta
    27001 tgaacagcta tggcgtcacg gaagcggcaa tcgactctag tttctacgac gaagaactgt
    27061 cgaagctgcc aagtagcggc aatgtgccga ttggtcaggc gtggctgaac gcacgcttct
    27121 acatcttgga cagccagttg aatccggtgc cgatcggcgt actgggcgag ctgtgcattg
    27181 gcggtgccgg ggtggcacga ggctacctga atcgtgcgga cctgacggcc gagaagttcg
    27241 tggcaaaccc gtacgtaccg ggtgaacgat tgtaccgcac aggtgacttg gcgcggtgga
    27301 tgccggacgg caatgtggac tttatcggcc ggatggatta tcaagtgaaa atccgcggtt
    27361 accggatcga gctaggcgag attgaaacgg cgatccagcg ggtgccgggc gtgcgtcaag
    27421 cggtagtcat cgaccggacg gatgagcgtg gacacaagta cttgtgcgga tacatcacgg
    27481 gagaagacga gctgcggatc gaggaggtac aggccgaact ggaagccggg ctgccagcgc
    27541 acatggtgcc agcacgcctg atgcgactgg agacgatccc tctgaccagc aacggcaaaa
    27601 tcgaccg
//
