LOCUS       NZ_JANAVN010000018     18908 bp    DNA     linear   CON 26-JUL-2024
DEFINITION  Paenibacillus sp. Lou8.1 NODE_18_length_129844_cov_146.855780, whole
            genome shotgun sequence.
ACCESSION   NZ_JANAVN010000018
VERSION     NZ_JANAVN010000018.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. Lou8.1
  ORGANISM  Paenibacillus sp. Lou8.1
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 129844)
  AUTHORS   Gonzalez-Pimentel,J.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAY-2022) Agroquimica, Microbiologia Ambiental y
            Conservacion de Suelos, Instituto de Recursos Naturales y
            Agrobiologia, Av. Reina Mercedes 10, Sevilla 41012, Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024213565.1-RS_2024_07_26
            Annotation Date                   :: 07/26/2024 02:53:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,316
            CDSs (total)                      :: 5,255
            Genes (coding)                    :: 5,159
            CDSs (with protein)               :: 5,159
            Genes (RNA)                       :: 61
            rRNAs                             :: 3, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 40 of 96
            Pseudo Genes (incomplete)         :: 74 of 96
            Pseudo Genes (internal stop)      :: 9 of 96
            Pseudo Genes (multiple problems)  :: 25 of 96
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:00:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 110936
            Orig. end                         :: 129844
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JANAVN010000018.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..18908
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..18908
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18908
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12583](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12583
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            265..2481
                     /locus_tag="NLX78_RS23020"
                     /old_locus_tag="NLX78_23000"
     CDS             265..2481
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349411.1"
                     /locus_tag="NLX78_RS23020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_23000"
                     /product="DUF5702 domain-containing protein"
                     /protein_id="WP_254351620.1"
                     /transl_table=11
                     /translation="MFGKGHNTKDGESGAVTVFLILILAVMFGFIAVFIDYARIAALHV
                     QTERLTHAAVRSVMSAYDPTLQQEYGLFAYGEGGGEQIMVKVLNDSARRTARAETLPLM
                     NMKLDSSSLKMERELGKYAIFNEQIREEMKYKAPVDFTFEVLEKLKPLSQNMKEASHTV
                     DLLKRLQKLYDRREAKLDDMLEKQRKAGAYMEEVRKRIIKQRGTYMPNQYIWDPLEVVA
                     DIAAQYKHYVHVYEDNKKSVDDVKIMQMEKYARRARAALDRLRQIMAQAGEEHDKLLLE
                     AKEPLNEAQQINEEMRKVIAQYKQRAANAGYDEVSAAPTPSGAGSNADPSVGSARQKAE
                     DLLIPDKEFEQWEAEIEKQRTSINTANNRITSMMRTLSFYTDPFLNADMLKQEVASTLK
                     EIDKYLSAYAWTGPSNVLDGEAKMMDTRRGPDEERKKMEKEAKNKLKQAYRIIEVLSKG
                     KQSAEQFRNLERYYNESISFNQSTSSPSVSADLSYDTYDAAGASMDSMDGLYGSASNLL
                     TQLGDEFYQNEYALSYFHHVDFSRFGSLAGSGGNVGNAAQILGDQLEVNNQEVEYILYG
                     FHNPTGNLASAYGEIFAMRLAIRTMEGLVKNSSKGNPLVVLAAALLYGVEKAIEDMIML
                     AQKGDVPLSDFLKFRMTYKDHLRLFLMLHSNNERKMSRMLALIRLNTDVNPAERQTYAT
                     GEVKNGMRLWFLPGVMKMLGTASKEGESIKGSVYYVTKTAHFSY"
     gene            2450..3445
                     /locus_tag="NLX78_RS23025"
                     /old_locus_tag="NLX78_23005"
     CDS             2450..3445
                     /GO_process="GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686582.1"
                     /locus_tag="NLX78_RS23025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_23005"
                     /product="TadE/TadG family type IV pilus assembly protein"
                     /protein_id="WP_254351621.1"
                     /transl_table=11
                     /translation="MSRKQRIFPINQYLRQVCGQERREQGSIVLEASLVLPMFLFFIIF
                     LIYMVQMTLVSTALQTTASEAVKQVSTKIYPVSLAVEAASAKIDAVREPLDELPKLSVS
                     EYASQFAAQLPPPIGDWVESAVQGGQKPMEELRGRFTEAALDPVLKPMLKPFMEESILE
                     YDRIHITSVHVPALTGTKDPYFRVELSYELPMKVPFLYRSIVLQAAAEERLWIGDTGEG
                     AGTGNATGDKDAQHSIQLLVKPEPAVKGVYNLIKAKVEPRTTANLSVLYKSGESTAQHL
                     GWTSANADGIIEWNWFVGTNTTPGQWSFVIETEDGQRIEVPFTVEKPADG"
     gene            3540..4052
                     /locus_tag="NLX78_RS23030"
                     /old_locus_tag="NLX78_23010"
     CDS             3540..4052
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429370.1"
                     /locus_tag="NLX78_RS23030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_23010"
                     /product="prepilin peptidase"
                     /protein_id="WP_254351622.1"
                     /transl_table=11
                     /translation="MMWMYIVCGVLLAIALVTDLRSMKIPNKLTLPGIVVGLVFNTLFG
                     GWDGFLFAVAGLGTGFGFMLILYWMGAVGAGDVKLFGLIGAWTGAAFAWQSALYSIFFA
                     GIIGIGILLWKRETIMRLRRVAFNLGGFFLFRSGKALTSGNEAHLRFPFMTAVIPGAIS
                     AYLYFLP"
     gene            4116..5963
                     /locus_tag="NLX78_RS23035"
                     /old_locus_tag="NLX78_23015"
     CDS             4116..5963
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686584.1"
                     /locus_tag="NLX78_RS23035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_23015"
                     /product="DUF6382 domain-containing protein"
                     /protein_id="WP_367988630.1"
                     /transl_table=11
                     /translation="MLGLSRDFARNGGTFMILNKEDGLKTDDLNSVQTGMMTGNRIPGL
                     LELRIKEVDFQIELHYDISGQRMLSQLWKGGGVSTSDFYRILYEVADALHRSPQYMLDI
                     RQFILHEDYIFLSGSGTRETASLTYVPLRSVQYAGQTGSQFKQMVIRLMTRVAHFQGEY
                     IQRILDLCDRNEFELGLLKELLLQGMKAGTESASVQGESMEERAFSSADPLISAHTSHV
                     SHTSHTSHVSHTSQGNYTDRGGTNGQEHRETLQEIQELKRINRLKPSMKPEEDSELVTE
                     NEVEDMEPGLQKYKTYIALGCLLASAIVWRYIYLDHPETVPLIISVVLTLVLVAVAYIS
                     WTGKWERNRTSSHMYSDSVPVLDSEWLGTTSSPAQRKNDRYQVDKLTGFVAGQHHQDKR
                     SSDLSDQGQESWRWTFPNSESKSVGDRVTEDREKTSANFDLHEPSWKGAEQGNELEASD
                     TSEAYYKSLSGVTELLNAASKQETMLLRPDQEIQISPVQQSPIACLDRKPPGSGGTERI
                     RLQPDQFVAGSFIIGRDPQLVQFVEHTDGASRSHIELCIVTGEHSHIVKDLSSTNGTVL
                     NGEPMVPYKEYTMKDGDTFKIAGVSYTYRLDSFKSSNAS"
     misc_feature    6268..6281
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.28"
                     /tool="antismash"
     misc_feature    complement(6269..6282)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.71"
                     /tool="antismash"
     gene            6599..7882
                     /locus_tag="NLX78_RS23040"
                     /old_locus_tag="NLX78_23025"
     CDS             6599..7882
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002150929.1"
                     /locus_tag="NLX78_RS23040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_23025"
                     /product="pitrilysin family protein"
                     /protein_id="WP_254351624.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 2.2e-23,
                     bitscore: 76.4, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDIHLSSSEHNGLQLHLCNTDKFKTISLILTMKAPLQKDLTTAR
                     ALVPHILTGGSTKYPNRKRIQRKLDEMYGATLFPDVQKKGDDQIITFRMEIAADQFLTL
                     SNSLLESSLDLLHEIVYSPTLVNGVFNSSIVEQEKRSLRQRLVSMYDEKILYANVRLIE
                     EMFRGETYEFPASGREEDIAALNASFIYQVYEELLQNSRFDLFIVGAFNANEAKLMAQH
                     IFSEQHNNKPIVAISSNRKGAGGVKIVQDKMDVKQGKLLLGYRTFSTIQDEDYEATRVA
                     NAIFGRFPSSKLFLNIREKESIAYFVHSQIESSKGLLITMAGIDFKNYEHAVEIIREQE
                     YAMKQGDFTEGELEKAKALLISLLLEAHDTPLGIMEMAIQAVDHGMSNTIGNRIKRLSK
                     VSKNDVIQAVNKWELDTIYFLNRKEELQ"
     gene            7879..9162
                     /locus_tag="NLX78_RS23045"
                     /old_locus_tag="NLX78_23030"
     CDS             7879..9162
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002150927.1"
                     /locus_tag="NLX78_RS23045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_23030"
                     /product="pitrilysin family protein"
                     /protein_id="WP_254351625.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.7e-18, bitscore:
                     59.6, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 2.3e-14,
                     bitscore: 47.1, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSIIYNKLGETIHYDRLANGLEVFVLPKKGFHKTVATFTTKYGS
                     VDNSFSVQGKSDFTQVPDGTAHFLEHKMFESEQGDVYHTFAKQGAFVNAFTGFTRTAYT
                     LSATSNINRNLESLLDFVQEPYFTDETVEKEKGIIEQEIRMYEDNPDWRARFGILRNMY
                     KSHPVKIDIAGTIASINQITKEDLYSCYNTFYHPNNMLFFVIGPVIPEKIMNLIQNNQQ
                     KKNFWEPENILRIFPDEGAEVNRKSCVMRLPVQTPKVFIGHKERDPGRQGQKLLKYELS
                     LKVLLELMFGSSSEVYEKMYADGYLDKPFTFDYTNENGFGYSLIGGDSREPEIIASFIN
                     ETIFRLKKEGIQKEDAQRVIKKELGSFLSAINSPQFIANQFTRYRFNEMDLFEVLPTLE
                     NLTEEDLTDVLHLHFSDESRTLLIVKEE"
     gene            9510..>9615
                     /locus_tag="NLX78_RS23050"
                     /old_locus_tag="NLX78_23035"
                     /pseudo=""
     CDS             9510..>9615
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016718230.1"
                     /locus_tag="NLX78_RS23050"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="NLX78_23035"
                     /product="ABC transporter ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSNLLEIKN"
     gene            10001..12583
                     /gene="lanKC"
                     /locus_tag="NLX78_RS23055"
                     /old_locus_tag="NLX78_23040"
     CDS             10001..12583
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="NLX78_RS23055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_23040"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_254351626.1"
                     /sec_met_domain="micKC (E-value: 6.9e-138, bitscore: 454.1,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1e-19, bitscore: 64.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.6e-14, bitscore:
                     46.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPNSEYYGKVEISENANTYELNEVPDTYTVIAENDSVWTYYHFK
                     GSTLPEQGWKIHITTLMEDVQSVLNKVARICIENKIEFKHLKDRRSFIEMNSKNANRAS
                     SGKFITIYPTSNEVFVELLEMLSLATQEFKKGPYILSDKRWKTSNVFYRYGGFKRIVNE
                     QGQHCIRDEQGNLIEDQRNPFYQVPDFVKDFDDYLNSINISGDSETEEEKNLERYKIEM
                     ALSYSNAGGVYLATRKKDNLKVIIKEARPNAGLDGVDQDALTRQKKEYDALTKLKDVAG
                     VVNLIEYFKEWEHYFLVEEFIEGQDLRKWLAQTFPYFRDGDNLNNHANNVKKILLQVFT
                     LIDEMHSNGVAMGDLQPANIMVTEELAVSIIDFETATPVHSEEKMSMATIGFVSQEMKV
                     SGARDWFGFQRLVRYLALPVLSSEDLEGYLQYNHLNWIKENYEASFYNFIIDMEDKSNK
                     RINDYQKYSPGEINLNDRTNDFNVDSIVSKLIKGVQNSLTSDERLINGDIRQFEMKDGK
                     YNFLTGGSGAAFTLNKNNASIVEVDNWIENYLLENVSHIEGNGLFTGKTGTWALLYDKG
                     YKETVLYELKLLRDNIHESNISLRSGLSGIGLFIISLYLETGDSEHLQFARVIEELIEV
                     NRVKAESLKANDWMAVEIGAIDGLSGVSLFYSALYSITHDKKYLNQAESLIREDLERTQ
                     KDDMTGVLQTLDNRNRLLPYLSGGSIGIAISIWFLNHVSGQNLYREEMDAILQLSKTRC
                     TISGSLFDGAGSLLLLPSMVNCVEQRNKMIGEILNLLNIFLIEKNGCYVYPGQFSYRLA
                     DDIYTGSSGIILALMAIVKENPLYWLPLVNSDEFLTRTKSKVTSVGSS"
     gene            12597..12689
                     /locus_tag="NLX78_RS26810"
                     /old_locus_tag="NLX78_23045"
     CDS             12597..12689
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="NLX78_RS26810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_23045"
                     /product="class III lanthipeptide"
                     /protein_id="WP_367988632.1"
                     /transl_table=11
                     /translation="MNDLEQEKEVKGVNAVLELQKLAHAADGKG"
     gene            12804..12941
                     /locus_tag="NLX78_RS23060"
                     /old_locus_tag="NLX78_23050"
     CDS             12804..12941
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="NLX78_RS23060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_23050"
                     /product="class III lanthipeptide"
                     /protein_id="WP_175405252.1"
                     /transl_table=11
                     /translation="MNEVLELQKLAHDVDGKGQAMEATITTITTTLTTVGNSSISIWGC
                     "
     CDS_motif       12804..12869
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNEVLELQKLAHDVDGKGQAME"
                     /locus_tag="NLX78_RS23060_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12870..12941
                     /prepeptide="core"
                     /locus_tag="NLX78_RS23060_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-1.90"
                     /molecular_weight="2143.4"
                     /monoisotopic_mass="2142.2"
                     /core_sequence="ATITTITTTLTTVGNSSISIWGC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEVLELQKLAHDVDGKGQAME"
                     /leader_location="[12803:12869](+)"
                     /alternative_weights="2161.4"
                     /alternative_weights="2179.5"
                     /alternative_weights="2197.5"
                     /alternative_weights="2215.5"
                     /alternative_weights="2233.5"
                     /alternative_weights="2251.5"
                     /alternative_weights="2269.6"
                     /alternative_weights="2287.6"
                     /alternative_weights="2305.6"
                     /alternative_weights="2323.6"
     gene            13057..13890
                     /locus_tag="NLX78_RS23065"
                     /old_locus_tag="NLX78_23055"
     CDS             13057..13890
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (65-167). E-value: 2.1e-07. Score:
                     21.2. Matches aSDomain: nrpspksdomains_NLX78_RS23065_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="NLX78_RS23065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_23055"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_254351627.1"
                     /transl_table=11
                     /translation="MEKLLEIAQNPEPFEKGTQEIWLDSDRADLVLKGHFDESIPGGSK
                     GSDFILETVEFISKIASVENYRKVIDLGCGPGLYSQKLAFKGYDVIGVDFNKTSIDYAI
                     NEAEKNGLEINYRIEDITDINIDNEFDLALLIYQIYSVFSPEDRRKILGNIHRGLKPGG
                     LVLLDVLSDVSYEKFPQNLMWGLARKDSPFSDRKHLMLHASMKYPDQVSLEKIVLIFGD
                     GEIVNYNYWNQHFSIESFEKEVNDAGFTLEKVYADVNGGDHVSDSEFFAAVLKKT"
     aSDomain        13252..13557
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NLX78_RS23065_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="2.10E-07"
                     /label="NLX78_RS23065_oMT.1"
                     /locus_tag="NLX78_RS23065"
                     /protein_end="167"
                     /protein_start="65"
                     /score="21.2"
                     /tool="antismash"
                     /translation="YRKVIDLGCGPGLYSQKLAFKGYDVIGVDFNKTSIDYAINEAEKN
                     GLEINYRIEDITDINIDNEFDLALLIYQIYSVFSPEDRRKILGNIHRGLKPGGLVLL"
     gene            <14431..15047
                     /locus_tag="NLX78_RS23070"
                     /old_locus_tag="NLX78_23060"
                     /pseudo=""
     CDS             <14431..15047
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309540.1"
                     /locus_tag="NLX78_RS23070"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="NLX78_23060"
                     /product="WXG100 family type VII secretion target"
                     /pseudo=""
                     /transl_table=11
                     /translation="GEVIAGIDEEGLSVAVSSTGVGSIIGVPGLIGSAALAAHGGTTAV
                     KSASGIGKSPAELWHMAKVEVKIQKKWRLSIKKVNL"
     gene            15048..15377
                     /locus_tag="NLX78_RS23075"
                     /old_locus_tag="NLX78_23065"
     CDS             15048..15377
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012819198.1"
                     /locus_tag="NLX78_RS23075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_23065"
                     /product="hypothetical protein"
                     /protein_id="WP_254351628.1"
                     /transl_table=11
                     /translation="MSVSVMILEPQNEFEKSFFLPLASESFFNECWQPAIESLGLQWID
                     LFSTGVDVEEEDLPIILSELRQLQNWAERNLEEDHKNKLVERVITLIEKLPSAFQRKEA
                     VVFIG"
     gene            complement(15500..16414)
                     /locus_tag="NLX78_RS23080"
                     /old_locus_tag="NLX78_23070"
     CDS             complement(15500..16414)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309284.1"
                     /locus_tag="NLX78_RS23080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_23070"
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="WP_254351629.1"
                     /transl_table=11
                     /translation="MNIIVCGGTGLVGSALVKSLLDDGYTVKVVTRKPLVGHEASPRLQ
                     YMSWNELKQKPEVLEGTDAVVNLAGETLNQRWTDKSKQRILQSRLLSVARLAQALNALQ
                     KKPKVIIQASAVAAYGTSLTETFDETSPRCSEDFLSQVVEQWEEAANAYPSDSRLIKLR
                     ISLVLDRKKGAFPLMKMPYSFGFGGKIGSGHQWMSWIHIEDIVRLITYCIHTTEIVGAV
                     NASSPHPLTNDQFGRTVATVYHRPHWFPVPSILVSKLVGEMSTLVLDGQKVLPRKALEH
                     GFKFNYPSLKDALEELHSSQKQH"
     gene            16712..17839
                     /locus_tag="NLX78_RS23085"
                     /old_locus_tag="NLX78_23075"
     CDS             16712..17839
                     /EC_number="3.1.21.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309285.1"
                     /locus_tag="NLX78_RS23085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_23075"
                     /product="deoxyribonuclease IV"
                     /protein_id="WP_235307806.1"
                     /transl_table=11
                     /translation="MLKIGSHVSFSDKGLLSATKEASSYGSSSFMIYTGAPQNTRRKPM
                     ESMYLEEGKQLMAEKGMEDIVVHAPYIINLGSYKENTYELAVSFLQEEIRRTHAIGVKN
                     IVLHPGAFTDKDAEYGIGRIADGLNEVLNGVKETDVNIALETMAGKGTEMGRSFEEIAS
                     IIDKVEHNERLTVCMDTCHIHDAGYDIVNDLDGVLEQFDRIVGLNRIAVVHINDSKNPV
                     GAHKDRHTPIGSGWIGYQTIHNVVHHEALQGRPFILETPWIGKEAKTQRPMYEVEIALL
                     RGNVKERFGDEFLGQVEQLHSFFKKQDVDVRKFVLDTWTLLKNDAKARKADPREPLERL
                     YDMITEAALFPDLSEEHINQRLIAWFAGSHLPVTV"
     gene            17862..18761
                     /gene="purU"
                     /locus_tag="NLX78_RS23090"
                     /old_locus_tag="NLX78_23080"
     CDS             17862..18761
                     /EC_number="3.5.1.10"
                     /GO_function="GO:0008864 - formyltetrahydrofolate
                     deformylase activity [Evidence IEA]"
                     /GO_process="GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="purU"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228: methionyl-tRNA formyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369971.1"
                     /locus_tag="NLX78_RS23090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_23080"
                     /product="formyltetrahydrofolate deformylase"
                     /protein_id="WP_254351630.1"
                     /transl_table=11
                     /translation="MEIHVKHQPNSTLSAHENRARMLVSCPDGPGIVAAVSRFLYEHGA
                     NIVQSDQYTMDPSGGMFFMRIEFDLPNLSATQPQLEQDFAAVAEQFRMEWTISAVSRKK
                     KLAIFVSKEDHCLVELLWQWQAGDLDADISLVVSNHPDMKEYVESFGIPYHHIPVTAHT
                     KPEAERRQLEVIGEDIDVIILARYMQIISPKFIEHYRNRIINIHHSFLPAFVGGKPYAQ
                     AYNRGVKIIGATAHYVTEELDGGPIIEQDVQRVSHGDDVNELKRIGRTIERVVLARAVK
                     WHAEDRILVHENKTVVFN"
ORIGIN
        1 agttaaataa gatagtgaag gtacctttgc tgaatcagtt tttagatcag acagatttgc
       61 aaggggaaat gagttctggc gtggtcgaac ctgtagaatg gattcgtacg gtggagttgg
      121 tccgttatta tggtgcgaag tttatgggca gaggatcatg tgaaaaggta gattcggcag
      181 ttgtagggaa agtattgatg caatatggtc aaaacggtca gtgagaagta agtaatagga
      241 atgtaactgg aaaggaggaa gcgggtgttt ggtaagggac acaatacaaa ggacggggaa
      301 tcaggtgctg tcacggtctt tttaattctg attttggcgg ttatgttcgg ttttattgct
      361 gtatttattg attacgcgag aattgctgca ctgcatgtgc agaccgaacg gctgacccat
      421 gcggcggttc gttcagtgat gtctgcttat gatccgacat tacaacagga gtacggtttg
      481 tttgcttatg gcgaaggcgg cggagaacaa attatggtca aagtgctcaa tgacagcgcg
      541 cgacgtacgg cacgcgcaga aacgctaccg cttatgaata tgaagctgga ttctagttcc
      601 ttgaaaatgg aaagggagct tggtaaatat gccatattta acgagcagat ccgtgaagag
      661 atgaagtata aagcacctgt cgattttacg tttgaagtgc tcgaaaagct aaagccgctc
      721 tctcaaaata tgaaagaggc ttcacatacg gtagatttgc tgaaacggct gcaaaagctg
      781 tacgacagac gagaggccaa actagatgac atgctggaga agcagcgtaa ggcaggagct
      841 tatatggaag aggttcgtaa gcggattatt aaacagaggg gcacctatat gcccaatcag
      901 tatatatggg acccgcttga ggttgtagct gatattgccg ctcaatataa gcattacgta
      961 catgtatatg aagacaataa gaagagtgtg gacgacgtta aaatcatgca gatggaaaaa
     1021 tatgcacgta gagcgagggc agcgcttgat cgcctgcgtc agatcatggc tcaggctgga
     1081 gaagaacatg ataagctgct tctggaagcc aaggaaccgt taaatgaggc ccaacagatt
     1141 aatgaagaga tgcgcaaagt cattgcccaa tataagcaga gggcggccaa tgcaggctac
     1201 gatgaggttt cagcagcacc tacaccaagc ggagcaggct ccaacgcaga tccgtcggta
     1261 ggaagcgcac ggcaaaaagc agaggatttg ttgattccag acaaggaatt tgagcaatgg
     1321 gaagcagaaa ttgaaaagca acggacttct ataaatactg ctaacaatag aataacgagt
     1381 atgatgcgta cattatcttt ttatacagat ccatttttga atgcagacat gctcaagcaa
     1441 gaagtcgctt caacgctcaa agagatagat aaatacttga gtgcgtacgc ttggacggga
     1501 ccttcgaatg tactcgacgg tgaagccaaa atgatggata cgcgacgtgg accggacgaa
     1561 gaacgcaaga aaatggaaaa agaggcgaaa aacaagctca aacaagccta tcggatcatt
     1621 gaggttcttt ccaaaggtaa acaaagtgca gaacaattcc gaaatctgga gcggtattac
     1681 aatgaaagta tttcgtttaa ccagtctaca tctagtccat ctgtatccgc tgatttgtcc
     1741 tatgacacct atgatgcagc gggagcttcc atggatagta tggatggtct atacgggtcg
     1801 gcatccaatt tactgactca actgggagac gagttttacc agaatgaata cgcgctttct
     1861 tacttccatc atgtggattt tagccgtttt ggcagtttgg ccggatcggg tggaaatgtg
     1921 ggaaatgctg cacagatttt gggagatcag ctggaggtga ataatcagga agttgagtac
     1981 atcctgtatg ggttccataa tccgacgggt aatctggcat ccgcctatgg agaaattttt
     2041 gctatgagac ttgccattcg aacaatggag ggattggtta aaaacagctc aaaaggtaat
     2101 ccgctggtcg ttttggcggc agctttgtta tatggagtag aaaaagcgat agaagatatg
     2161 attatgctgg cacaaaaggg ggacgtgcca ttgtctgatt ttctaaaatt tcgaatgaca
     2221 tacaaagatc atttgcgatt gttcctgatg ctccatagca ataatgaacg aaaaatgtcc
     2281 cgtatgcttg ctctgatccg cctgaataca gatgtcaatc ctgctgagcg gcaaacgtat
     2341 gcaacgggtg aggtcaagaa tgggatgagg ctgtggtttc tacctggggt aatgaagatg
     2401 ctcgggaccg cctcaaaaga aggcgagagc attaagggaa gtgtgtacta tgtcacgaaa
     2461 acagcgcatt tttcctatta atcagtatct acggcaggtt tgtgggcagg agcggcgtga
     2521 acaaggaagt attgttttag aagcgtcact cgtgttgcca atgtttctgt tttttattat
     2581 ttttctcatt tatatggttc agatgacgct ggtatccaca gccttgcaga ccaccgcttc
     2641 agaagcggtt aagcaggttt cgactaaaat ctacccagtt tctctagccg tggaggcggc
     2701 gtccgcgaaa atagatgcag tccgtgaacc gctggatgaa ttgcccaagt tatctgtgag
     2761 tgaatatgca agccaattcg ctgcccagtt gccacctcca attggtgatt gggtagaaag
     2821 cgctgttcag ggcggtcaaa agccgatgga ggagctgcgg gggcgattta cggaagctgc
     2881 acttgaccct gttctgaagc cgatgctaaa gccttttatg gaggaaagca ttctggagta
     2941 tgaccgtatt catataacga gcgtacatgt acctgctctt acaggaacta aggaccctta
     3001 ttttagagta gagctgtcgt atgaactgcc gatgaaggtc ccctttctgt atcgcagcat
     3061 tgtgcttcag gcggcggcag aggaacgtct ttggattggc gacacagggg aaggagcagg
     3121 tacaggaaat gcgacaggag ataaggatgc gcagcattcc atacagttgc tcgtcaagcc
     3181 tgaacctgct gtgaaaggtg tgtacaattt gatcaaggcc aaggttgagc ctaggacgac
     3241 tgctaacctt tcagtacttt ataagtcggg tgagagcaca gctcagcact tgggctggac
     3301 ctctgccaat gcggacggga ttattgaatg gaactggttt gtgggaacga atacaacacc
     3361 cggtcaatgg agctttgtga ttgaaacgga ggacggtcaa cgtatagaag ttccgtttac
     3421 cgtggaaaag ccagctgatg gatagatagg atcgactcga catagacgga caggaataac
     3481 cacgatggaa aatgatttgg tagtctgcta gttttatttt ttaaaggggg aagatcgcat
     3541 tgatgtggat gtatattgta tgcggagttc tgctcgcgat tgcgttagtt acggatttac
     3601 gtagcatgaa aatccctaat aagcttacat tgcccggtat agtggtaggc ttggtgttca
     3661 atactctatt tggagggtgg gacggttttt tatttgctgt tgctggactg ggtaccggat
     3721 ttggtttcat gctgattttg tactggatgg gagctgttgg tgcaggagat gtaaagctgt
     3781 tcggcttgat tggagcatgg acaggtgctg cttttgcatg gcagtcagct ttatattcga
     3841 ttttttttgc aggtattatt ggcataggaa ttttgctatg gaagagggaa accatcatga
     3901 gactgcggcg cgtggctttt aatttaggag gattttttct atttcgcagc ggcaaagcgc
     3961 tgaccagtgg aaatgaagcg cacctcaggt ttccttttat gacggcagtc attccgggag
     4021 cgatcagtgc ttatctttac ttcttgccat gacatgtccg ctgggggaga tcatgctacc
     4081 tcacggagat aggaaattgt taaggaggtc atgaattgtt gggtttaagc agggattttg
     4141 cccggaacgg cgggacattt atgattctaa acaaggaaga cgggctcaag accgatgatt
     4201 taaattccgt acagaccgga atgatgactg gtaatcggat tcccggtctg ctggaactta
     4261 gaataaagga agtcgatttt cagattgagt tacattacga catttcgggg caacgcatgc
     4321 tttcccagtt atggaaaggt gggggcgtgt cgacttctga tttctatcgg attctttatg
     4381 aagtggcaga tgccctccat cgcagcccgc aatatatgtt agatatccgc cagtttattt
     4441 tgcatgagga ttatattttt ctaagtggtt caggtactag ggaaaccgcc agtttaacct
     4501 atgttccttt acgcagtgta cagtatgcag ggcaaacagg cagtcaattt aagcagatgg
     4561 ttattcgttt aatgactcgt gtggcccact ttcagggaga atatatacaa cgcatactgg
     4621 atctgtgtga tagaaatgaa tttgaattgg gattgctaaa ggaactgtta ttacaaggaa
     4681 tgaaggccgg tacagagagt gctagcgtgc agggagaaag tatggaggaa cgagcttttt
     4741 catcagccga ccctctcata tctgctcata cctctcatgt ctctcatacc tctcatacct
     4801 ctcatgtctc tcatacctca caggggaact atactgatcg tggcggaaca aacgggcaag
     4861 agcatcggga aactctgcag gagattcagg agcttaaacg gatcaatcga ctcaaaccgt
     4921 ccatgaaacc agaggaggat tctgagcttg taacagaaaa cgaagtagaa gatatggagc
     4981 ctggattgca aaaatataaa acgtacattg ctcttggatg tctgctcgct tcggccatcg
     5041 tgtggcgtta tatttatctg gatcatccag agacggtacc gttgatcatt tccgtggtgc
     5101 tgaccttggt acttgtcgcc gttgcttata taagctggac ggggaaatgg gagcgcaata
     5161 gaacttcatc tcatatgtac agcgattcag tacctgtatt ggattcggaa tggttaggaa
     5221 ctacttcttc cccagcgcag cggaaaaatg atcgttatca ggtagataaa ctgaccggat
     5281 ttgtagcggg acagcatcat caagacaagc gatcttccga tttgagtgat caagggcagg
     5341 agagctggag atggactttt ccaaactcag aatctaaaag cgtgggagac cgagttacgg
     5401 aagacaggga gaaaacttca gcaaattttg acttacacga gccatcgtgg aaaggtgcgg
     5461 agcagggaaa tgaattggaa gccagtgata ccagtgaggc ttattataag tctctctccg
     5521 gggtaacgga gctgctaaat gctgcatcta agcaggaaac catgctgctt cgtccagatc
     5581 aagagataca gatttcacct gttcagcaat caccgattgc ttgcctggat cgcaagccac
     5641 caggtagtgg agggaccgag cgcatccggt tgcagccaga ccaattcgtt gcaggcagct
     5701 ttatcatcgg gagagacccg caactggtcc agtttgtgga gcatacggat ggagcctccc
     5761 gttctcatat tgagctttgt atagttacag gagaacatag ccacattgtt aaggatttat
     5821 cctcgacgaa cggaactgtt ctgaatggag agcctatggt gccttataag gagtacacaa
     5881 tgaaggatgg agacactttt aaaatcgccg gggtatctta tacttatcgg ttggactctt
     5941 ttaaatcctc caatgcatca taaataaagg ttatatggct atatgtcaag aagaggcctg
     6001 ttatgttcag ggcttctttc tttgtaatag ggggctattc ataggaataa aatgagcatc
     6061 ttaaaaactt gcagtctgct tgaaagattg tgcctgacta aaaaaggttt gcgcataatg
     6121 agagaagtct attcatttca agggggattt acacaaatac aagttaaata acatatgaaa
     6181 atatgtgaat tgttactttt atcaaacaac cctttaatgg gttatttttt gtttcttcta
     6241 aaaatagttt tttatactca ttttctaatt ttatcataaa ataatacata tatttccttt
     6301 tatgtgttat ggttataagg tagcacataa aatagaaaag tatgtgtgcg tataccatga
     6361 agaaactgaa aacacatcaa ttatcttaac aggtgtctta gctcttacat caattgctcc
     6421 attgggtgct tccgctgcac ctactacagg aattgaagct aaaggagctg gaatatgcct
     6481 tctgttgaag agacgcactt ttcacattct catgtacatt tatgttatta tttatgatga
     6541 ttatgaagga attgtatttg tgaataacat ttctgattta gaatgaggga gataggagat
     6601 ggaagacatt cacctaagtt ccagtgaaca caacgggttg cagcttcacc tgtgcaatac
     6661 agataaattt aagacaatca gtttaatatt aacgatgaaa gcgcctcttc aaaaggattt
     6721 aacgactgca agagcattag ttccccacat tctgactggc gggtcaacaa agtaccccaa
     6781 ccgtaaacgc atacaacgaa agcttgatga aatgtatgga gcaactcttt tcccggatgt
     6841 acagaaaaag ggcgacgatc aaattattac atttagaatg gaaatcgctg ccgatcaatt
     6901 tctgacttta tctaactctt tactagaatc atctcttgat ttattgcacg agattgttta
     6961 tagtccaacg cttgtgaatg gagtgtttaa ttcctcaatt gtggaacaag agaaacgctc
     7021 tttaaggcaa cgacttgttt caatgtatga tgagaagatt ttgtatgcta atgtacgttt
     7081 gatagaagag atgtttagag gcgaaacgta tgagtttcct gcatccggga gagaggaaga
     7141 catcgctgca cttaatgctt catttattta tcaagtgtat gaagaactac ttcaaaatag
     7201 tcgctttgat ttattcattg ttggcgcatt taatgcgaat gaagccaaat tgatggcaca
     7261 gcatattttt tctgaacaac ataacaacaa acctatagtg gcgatttctt caaacagaaa
     7321 aggtgcgggc ggcgttaaga ttgttcaaga taaaatggat gtaaagcaag gaaagcttct
     7381 tttgggatac cgcacttttt cgacaataca agacgaggat tatgaagcga caagggtggc
     7441 aaatgcaatc tttggcagat ttccttcttc taaattattc cttaatatac gtgaaaagga
     7501 aagtattgct tactttgtac attcgcaaat tgaaagctct aaaggcttgc taataactat
     7561 ggctggaatt gattttaaaa attatgaaca tgcagttgaa ataataagag aacaagagta
     7621 tgcaatgaaa caaggtgact ttactgaggg cgaactggaa aaagcgaaag cgctgttgat
     7681 tagcctactg ctggaagcac atgatacccc tttgggaatt atggagatgg ctattcaagc
     7741 ggttgatcat ggaatgtcta atacgatagg aaaccggatt aaaagactga gtaaggtgtc
     7801 gaaaaacgat gttattcaag cggtcaataa gtgggagctt gataccattt atttcttaaa
     7861 cagaaaagag gaactacaat gaagtcaatt atctataaca aattaggaga gaccatacat
     7921 tatgatcgac tcgccaacgg tcttgaagtt ttcgtgcttc ccaagaaagg ctttcataaa
     7981 acggttgcga cattcacaac aaaatacggt tcagtagata acagcttttc agttcaagga
     8041 aaaagcgatt tcactcaagt tccggacgga acagcgcact tcctagaaca taaaatgttt
     8101 gaaagtgaac agggcgatgt ctatcatact tttgcaaaac aaggagcttt tgtcaatgca
     8161 ttcacaggtt ttacccgtac agcctacaca ttgtcggcaa cttctaatat caatagaaat
     8221 ctggaatcgt tgctggactt tgtacaggaa ccatatttta cagatgaaac ggttgagaag
     8281 gagaaaggga tcattgaaca ggaaatcaga atgtatgaag ataatccgga ctggcgcgcc
     8341 cgatttggaa ttctaagaaa tatgtacaaa agtcacccag tgaaaattga tatagccggt
     8401 acaatagctt cgattaatca aattactaaa gaggatttat attcttgcta taatacgttc
     8461 tatcatccca ataatatgtt attttttgtg attggacctg tgatacctga aaaaataatg
     8521 aatctcattc aaaataatca gcagaaaaaa aacttttggg aacctgaaaa cattctccgc
     8581 atattccctg atgaaggagc tgaagtgaac aggaagtcat gtgttatgag gctaccagtt
     8641 caaacgccta aagtttttat tggacataaa gaacgtgatc ccggaaggca aggtcagaaa
     8701 ttgcttaaat atgagctatc tttaaaagtt ttacttgagt taatgtttgg cagcagctcc
     8761 gaagtatacg aaaaaatgta cgctgacggt tacttggata agccgtttac ttttgattac
     8821 acaaatgaga acggttttgg ctattcgctt atcggcggag atagccggga accggaaatt
     8881 atagcatcat tcataaatga gactatcttt agactcaaaa aggaaggaat acaaaaagaa
     8941 gatgctcagc gagtaattaa gaaggaactg ggcagtttct tgagtgcaat taactcaccc
     9001 caatttatcg ctaaccaatt tacaaggtat cgttttaacg agatggattt attcgaggtc
     9061 ttgcccacac ttgaaaatct aactgaagaa gatcttacag atgtcttgca cttacacttt
     9121 tcagatgaat caagaacgct actaattgta aaagaggaat aaatttcatt aactgttctt
     9181 ttgtatttca attataagtc aaaaaaaact aatggtaaat gttgaaataa aatataatct
     9241 attgtataat atgaattaag aataagaaat tccataattt tggttttcac taacgataaa
     9301 tcctctacca tgaataccac atccacttct tttacaacaa gaagcaccct ctgttcttca
     9361 tcatttcttg agtttcagtt tatcttcgat gttatgtgaa aaaaatactg caacaacttc
     9421 aaatcatact tcttgttacg caaagtgtta ggattagaac aaacttcttc ttggtaaggg
     9481 ctttaaatac ttattatagg agtgaagtga tgtcaaatct gttggaaatt aaaaattaaa
     9541 aaatcatttg aagacaaagt tgttctaaaa gacgttacct tcaatgtgcc gaccggatca
     9601 atagtagggt tcatttatca tagcaacagc atacttagaa ttatctcttt agggatattc
     9661 atcgttttat ttggtggtgc gttgattcat ccactcattt acgttttcgg tccggagaag
     9721 tctgatacaa ttggaagtgg gatgggagaa gcttttgcct tttatgtttt gcagggagta
     9781 gtgagctatt tgacagaaca attatagctg ctaaattcaa atgtggattc gtatgtatat
     9841 gttccaatta tatatgtaat aattgtaatt ttgtgtatat ttctccctat ttatgtgaca
     9901 ctgttcattt atcgcaataa agaattctag ttattcctat ctttgaagaa tctgaatgga
     9961 ggagtgcttg atggaaggga atatgttata tcatagatac atgaaaccaa attcggaata
    10021 ttacggaaag gtagagatta gtgagaatgc gaatacgtat gagctaaatg aagttcctga
    10081 tacatataca gttatcgcag aaaatgattc tgtatggacg tattaccact tcaaggggtc
    10141 aactcttcca gagcaaggtt ggaaaattca tataacaaca ttaatggaag atgtacaaag
    10201 tgttctgaat aaggttgcac ggatatgcat agaaaacaag attgagttca agcatctaaa
    10261 ggacagacgg agtttcattg agatgaattc gaaaaacgcg aatcgcgctt cttccggtaa
    10321 gtttataaca atatatccta cgagcaacga agtgttcgtt gaattgttag aaatgctttc
    10381 cttagctact caagagttta agaaaggacc ttatattctt agtgataaga gatggaaaac
    10441 tagcaatgtg ttctataggt atggagggtt taaacgtata gtcaatgagc aaggtcaaca
    10501 ttgtatcagg gatgagcaag gtaatttaat cgaggatcaa aggaatcctt tttaccaggt
    10561 tcctgacttt gtaaaggatt tcgacgatta tcttaattcc attaatattt ctggagattc
    10621 ggaaactgaa gaagaaaaaa atttagagag gtataagatt gaaatggcac tcagctatag
    10681 taacgctggt ggagtatatc tcgcaactag aaaaaaggat aatttgaaag tgattatcaa
    10741 ggaagctaga ccaaatgctg gattagatgg agtggatcaa gatgctttaa caagacaaaa
    10801 aaaagagtat gatgctttga ccaagcttaa agatgtagct ggtgttgtga atttaattga
    10861 gtattttaag gaatgggagc attatttttt ggtagaggaa ttcattgaag gacaagactt
    10921 aaggaaatgg cttgcacaaa catttcctta ctttagagat ggggataacc ttaataatca
    10981 tgcgaataac gttaagaaga tattgttgca ggtcttcacc ttaatagacg aaatgcatag
    11041 taatggtgta gctatgggtg acttgcaacc agcgaatata atggtaaccg aggagctggc
    11101 cgttagtatc attgattttg aaacagctac gcctgtgcat tctgaagaaa aaatgagtat
    11161 ggctacaatt ggatttgttt cgcaagagat gaaggttagc ggtgcaagag actggtttgg
    11221 atttcaaagg cttgtcaggt atttagcgct tcctgtcttg tcttcagaag atttagaggg
    11281 atatcttcaa tacaaccatc tcaattggat taaagaaaat tatgaagctt cattttataa
    11341 tttcattata gatatggagg acaaatctaa taagagaatc aatgattatc agaagtacag
    11401 ccccggggaa attaatctga atgatcgaac aaatgacttt aacgtagact ctatagtgag
    11461 taagttgata aaaggtgttc aaaatagttt aacaagtgat gaaaggctca ttaacggtga
    11521 catccggcaa tttgagatga aagatgggaa atataacttc ttaactggag gaagcggtgc
    11581 agcctttact ctgaataaaa ataacgccag cattgtagag gtagataatt ggatagaaaa
    11641 ttatttgcta gagaatgtat cacatattga aggtaatggg ttatttactg gaaaaacagg
    11701 aacctgggct ttgctttatg ataaaggcta taaggaaact gtcttatatg aattgaaact
    11761 tctcagagac aatattcatg aatcgaatat ttctttacgc tccggtcttt cgggaatagg
    11821 attattcatt attagcttat accttgaaac tggggatagt gaacatttgc aattcgctag
    11881 agtaatagaa gagttaattg aagttaatag agtcaaggct gaatcgttaa aagctaatga
    11941 ctggatggcc gtagaaatag gtgcaattga tggattatct ggtgtgtctc tattctactc
    12001 agcactttat tcaattaccc atgataagaa gtatttgaat caggcagaat cattgatacg
    12061 ggaagatctg gagagaaccc aaaaagatga tatgacgggc gtattgcaaa cattggataa
    12121 tagaaatcga cttttaccat acctttcagg cggatctatt ggaattgcaa tttcgatttg
    12181 gttcttaaat catgtgagtg gacaaaatct gtatagagaa gaaatggatg caattttaca
    12241 attatcaaag acacgttgca ccatcagtgg aagcttattc gatggagcag gtagcctttt
    12301 gttgctccca tccatggtta attgcgttga gcaacgcaac aaaatgattg gcgaaatact
    12361 aaatttactt aatatattct taattgagaa gaatggatgc tatgtatacc cagggcagtt
    12421 ttcttataga ttggctgatg acatttatac aggtagttca ggaattatat tagcactaat
    12481 ggcgatcgtc aaagaaaacc cactttactg gctgccactt gtgaattcag atgagtttct
    12541 gaccagaaca aagtccaagg ttacatcagt gggctcttca taaaaatgat tgccaaatga
    12601 atgatcttga acaagaaaag gaggtgaaag gtgtgaatgc cgtactcgaa ttgcaaaaat
    12661 tagcacatgc cgcagatggt aaaggttaag cagtggaagc aattttacaa caacaagtgt
    12721 agggtcaaca attattttct actccaccat tagtagtcat atttgctaaa taatattttt
    12781 aattaagaag ggaggtgaaa agaatgaacg aagtactgga actgcaaaaa ttagcacatg
    12841 acgtagacgg taaaggccaa gcaatggaag caacaataac aacaataacc acgactctta
    12901 ctaccgtggg aaattcatcc atcagtattt gggggtgcta agtattcttg gttgatgtaa
    12961 aacaatgtgc aacggttgct tagctgcccc cagctaagca accgttaatt cctgtgtaca
    13021 cataaatgat taataataca tttaagggtg atgaggatgg aaaagttatt agaaatagcg
    13081 caaaaccctg agccatttga gaaagggaca caagaaatct ggcttgattc agatcgggct
    13141 gatcttgttc ttaaaggaca ttttgatgag agtatacctg gaggaagcaa gggtagcgat
    13201 tttattcttg agaccgttga gttcattagc aaaattgctt cggtagagaa ctatcgtaaa
    13261 gttattgatt taggctgtgg tcctgggctg tactcccaaa aattagcttt taaaggctat
    13321 gatgttattg gtgtagattt caacaaaaca tcaatcgact atgccatcaa tgaggccgaa
    13381 aaaaatggtc tagaaataaa ttacagaatt gaagatatta ccgacattaa tattgacaat
    13441 gaatttgatc tagcgctgct gatttatcaa atttatagtg tctttagccc agaggataga
    13501 aggaaaatac ttggtaacat ccaccgtggt ttaaaacctg gaggattagt tctgttagac
    13561 gttctgtcag atgtgagtta tgagaaattt ccgcaaaact taatgtgggg tcttgcaaga
    13621 aaagatagtc cattctcgga ccgaaaacat ttaatgctac acgcttcaat gaaataccct
    13681 gatcaagtct cgctagagaa aattgttctg atttttgggg atggtgagat cgtaaattat
    13741 aattattgga accaacattt tagcattgag agttttgaaa aagaagtgaa tgatgctgga
    13801 tttacgctcg aaaaggtgta tgcagatgtt aatggtggag atcacgtaag tgatagcgag
    13861 ttcttcgcag cagttttaaa gaaaacataa agggttcctg agaatgccaa acaagcaatt
    13921 cccccgttta attcaatcat tgatactttt tctttttttt caagatttga ctttttgtat
    13981 cgttaacctt aagcagaata gatgctttat ataaagaggg gcgggtatgc ttctcttttt
    14041 gttgtaatct gcccgtccgg tccataatct cgcttcattt gtgaaatttt ccagacttaa
    14101 tcatgtcatc tcagcgtatt tttgcaggga acccgcctta aaccaaattc gctccgccaa
    14161 ctgctgaagg cttcctcgct caccaagcga gtgggctgat attaatgcca tgtatataac
    14221 gtatggtaca tatcaagaaa gaagaaccca aagtgtcgga gatcagccgg tatatcagcc
    14281 taaccctcca atcgtaacct aactgatcaa cagcctggag gccaaggaag tggtggcgag
    14341 gcaagtcgcc cgtccaaccg cagagtgtgc cctgtagttc tgaccgagca aggatggact
    14401 gttgcacgca gattcaagag cagtatggtt ggtgaggtaa tagctggaat agatgaagaa
    14461 ggattatcag ttgctgtttc atctacggga gttggtagta taatcggagt acctggattg
    14521 attggctcag cagctttagc agcacatgga ggtacaacag cagttaaaag tgctagcgga
    14581 atagggaaaa gcccagcaga attgtggcat atggcgaagg tggaggtaaa aatccaaaag
    14641 aagtggagat tgtcaataaa aaaggtgaat ctataggaga attcgatgaa attgatttga
    14701 aaaagaaaat attctacgaa gataaatctg caaaaggatt agataaagta aatcctaaga
    14761 caggtttacc agctcaaacg ccccaagaat ttacggataa acaattatta aaaaagactc
    14821 gaaatcgaat caatgaacta gaaaataatg catttactac aagagcaaca aaaaatagtt
    14881 catgttatat tccccatctc gatagtatta aagatattcg ggaatttgta ttcagattag
    14941 atggtgatac acctgaattg aggaaagctg ccgagaacag cctaaatcag cttcaaaagg
    15001 agtttccaga ttataaattt agcgttcagt ttggaggcgg aaaataaatg tcagttagcg
    15061 ttatgatact cgaaccacaa aatgagtttg aaaaaagttt ttttcttccc cttgcgtcag
    15121 aatcattttt taatgaatgt tggcaaccag ctatcgaatc tctaggatta caatggatag
    15181 atttattttc aacaggagtt gatgttgagg aggaagacct acctattatt ttatctgagc
    15241 ttcgacaact tcagaattgg gcagaaagaa atttagagga ggatcacaaa aataaactcg
    15301 ttgaacgagt aataacactc atagaaaaac tgcctagcgc gtttcaacgt aaggaagcag
    15361 ttgtttttat agggtagtga tagtttggat taaagggagt ctactgggat aggctaaaat
    15421 gaaaatagat tacgctctaa aaaagaactc taagctggca gtgacactac ctaccagcct
    15481 ggagttcctc tttttagatt caatgctgtt tttgggaaga atggagttcc tcaagagcgt
    15541 ccttaagtga aggatagtta aacttaaatc cgtgctccag cgctttgcgc ggtagtacct
    15601 tttgaccatc caatacaagc gtgctcatct caccaactag ctttgaaacg agaatgctgg
    15661 ggacgggaaa ccagtgcgga cggtgatata ccgtagctac tgtcctccca aactggtcgt
    15721 tcgtcaaggg atgtggtgat gaagcattca ctgccccgac gatttccgtc gtatggatgc
    15781 agtacgtgat cagacgaacg atatcttcaa tatgaatcca gctcatccat tgatgaccac
    15841 tgcctatttt gccgccgaat ccgaagctat aaggcatctt catgaggggg aatgcccctt
    15901 tttttctgtc cagcacaagg ctaatgcgta acttgattaa acgggaatca gaagggtagg
    15961 cattggcggc ttcctcccat tgctctacca cctgagacag aaaatcttcc gaacagcgag
    16021 ggctcgtttc atcgaatgtt tcggtcaggg aagtaccata ggcggcaaca gccgaagcct
    16081 gaatgataac tttcggcttt ttttgtagag cattcaatgc ttgagccaac cgggcaacag
    16141 atagcagtcg tgattgaaga attctttgtt tggacttatc cgtccagcgc tgattcagcg
    16201 tttcgcctgc taaattaacg accgcatcgg tgccttccag tacttcaggc ttttgtttta
    16261 attcgttcca actcatatat tgcaaacggg ggctcgcttc gtgtcctacc agtggcttgc
    16321 gggtaacgac tttcacggtg tatccgtcgt ctagcaagct tttgaccagt gcactcccca
    16381 ccaatccagt tcctccacat acgatgatgt tcatggagcc agctctcctt ccgattcaca
    16441 aaaaaataca tctgttatag aatataaccc ttttcgagaa aaaaacttca tatgaatgta
    16501 cctttatacg gttaaggatg tcaattcatg attttattta cccttgtttg actaatatat
    16561 attcggatgt gtactttatc tacgtgttcc cttaatagag tcatttaaga aagctgccat
    16621 aaaagctatg ttgtttgatt tcaataatca cgttaaaatg attaaattaa aataagacaa
    16681 gcataacagg ataaggggat gaatcagaat catgctgaaa attggttctc atgtgtcctt
    16741 ctcggacaag ggtctgctca gcgctacaaa agaagcgtct tcttacgggt ccagctcctt
    16801 tatgatatac acgggagcac cgcaaaacac gcgccgtaag ccaatggagt ccatgtattt
    16861 ggaggaaggc aagcagttaa tggctgagaa gggaatggaa gatatcgtgg tgcatgcccc
    16921 gtatatcatc aaccttggct cttacaaaga aaatacctat gagcttgcgg tcagctttct
    16981 tcaggaggaa attcgacgca cacacgcgat tggtgtgaaa aatatcgtgc tacatccagg
    17041 cgcttttacc gataaggatg cagaatacgg aattgggcgt attgctgatg gtttgaacga
    17101 ggtactaaac ggtgtgaagg agacagatgt taacattgcg cttgaaacga tggcaggcaa
    17161 aggaacggaa atgggtcgta gctttgagga gattgcctcc attatagata aagtagagca
    17221 taacgagcgt cttacagttt gtatggacac ctgtcacatt cacgatgcgg gttatgatat
    17281 cgtaaatgat ctggacggtg tattagagca attcgaccgc attgtcggct tgaatcgcat
    17341 cgcagttgtt cacattaatg acagtaagaa tccagttggc gctcataaag accgacatac
    17401 tccgatcgga tcaggctgga ttggctatca gacgattcat aatgtggtgc atcatgaagc
    17461 acttcaagga cgtccgttta ttttggagac gccatggatt gggaaggaag ccaaaactca
    17521 gcgtccgatg tatgaggttg aaattgccct gcttcgcgga aatgtaaagg agcgctttgg
    17581 ggatgagttt ttgggtcagg tagagcaatt gcattcgttt ttcaaaaaac aggatgtgga
    17641 tgtccgtaaa tttgtgctgg acacctggac tctgctgaaa aatgatgcca aagcaagaaa
    17701 agccgatcca cgtgagccgt tggagcgtct gtatgacatg ataacggaag cagcactatt
    17761 tccagatttg agcgaagaac acattaatca acggttgatt gcctggtttg ccggcagtca
    17821 tttgccagtg acggtataag ctaaggggga ttaatagcca catggaaatt cacgtaaaac
    17881 atcagccaaa tagcactcta tcagcccatg aaaaccgcgc gcgtatgctt gtatcttgtc
    17941 cagacggacc aggtattgta gcggccgtgt cccgtttttt gtatgagcat ggggccaata
    18001 tcgttcaatc tgaccaatat acaatggacc cgtccggcgg tatgtttttt atgcggattg
    18061 aatttgatct gccgaatttg agtgcaaccc agccacagtt ggagcaggat tttgccgctg
    18121 ttgccgagca attccgtatg gagtggacga tttctgcggt cagccgcaag aaaaaactgg
    18181 ctattttcgt ttccaaagaa gatcactgtt tggtagaact gctgtggcaa tggcaggcag
    18241 gagatctgga cgcggatatt tcattggtgg ttagtaatca tccggatatg aaggagtatg
    18301 tggaatcatt tggcatcccg tatcaccata ttccggtaac agcccatact aaaccggagg
    18361 cggagcgtcg tcaactagag gtcattggcg aagacattga cgttatcatt ttggcccgtt
    18421 acatgcagat tatttcgccc aagtttattg agcattatcg caaccggatt atcaatatcc
    18481 atcattcctt tctgcccgca ttcgtgggtg ggaagccata tgcccaagcc tataatcgcg
    18541 gtgtgaaaat tattggtgct actgcgcatt atgtaactga agaattggac ggcggcccga
    18601 tcattgagca ggacgtgcag cgggtaagtc acggagatga tgtaaatgag ctaaagcgga
    18661 tcggtcgcac catagagcgg gtcgttttgg caagagccgt gaagtggcat gcagaggatc
    18721 gtattctggt tcatgagaac aaaacggtcg tatttaacta atcctaaaat tttagaagaa
    18781 aatttgtgaa tatatttttt ttgttaaaca aagcccgtcg cataacgggc tttcaggctg
    18841 tcgagaaagt ctcgacagct ttttttatgt tcattttatt taagacgaca ccgcgttaat
    18901 gttatata
//
