LOCUS       NZ_JANAVN010000010     24119 bp    DNA     linear   CON 26-JUL-2024
DEFINITION  Paenibacillus sp. Lou8.1 NODE_10_length_264709_cov_153.309834, whole
            genome shotgun sequence.
ACCESSION   NZ_JANAVN010000010
VERSION     NZ_JANAVN010000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. Lou8.1
  ORGANISM  Paenibacillus sp. Lou8.1
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 264709)
  AUTHORS   Gonzalez-Pimentel,J.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAY-2022) Agroquimica, Microbiologia Ambiental y
            Conservacion de Suelos, Instituto de Recursos Naturales y
            Agrobiologia, Av. Reina Mercedes 10, Sevilla 41012, Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024213565.1-RS_2024_07_26
            Annotation Date                   :: 07/26/2024 02:53:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,316
            CDSs (total)                      :: 5,255
            Genes (coding)                    :: 5,159
            CDSs (with protein)               :: 5,159
            Genes (RNA)                       :: 61
            rRNAs                             :: 3, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 40 of 96
            Pseudo Genes (incomplete)         :: 74 of 96
            Pseudo Genes (internal stop)      :: 9 of 96
            Pseudo Genes (multiple problems)  :: 25 of 96
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:00:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 228768
            Orig. end                         :: 252887
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JANAVN010000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24119
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..24119
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24119
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14119](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14119
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    6..24
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.79"
                     /tool="antismash"
     misc_feature    complement(31..44)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     gene            253..1173
                     /locus_tag="NLX78_RS16255"
                     /old_locus_tag="NLX78_16245"
     CDS             253..1173
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821230.1"
                     /locus_tag="NLX78_RS16255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16245"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_029516218.1"
                     /transl_table=11
                     /translation="MQQATGQVPVIRMEGVSKIISSKAIVDDLTLEVPAGQVFGFLGPN
                     GAGKTTTIRMMVGLISISKGDIHICGDSINTDFEKAVSHVGAIVENPEMYKFLTGYQNL
                     QHFARMSPGVTQERVDEAIRLVGLGNRIHDKVKTYSLGMRQRLGVAQAILHRPKLLVLD
                     EPTNGLDPQGIRELRDYLRQLTRTEGITVFVSSHLLSEMELMCDRVAIIQSGRLVDIKQ
                     LKNTGEEVQTAEIAFEVNDAEQAYALAGAGRVEGNQLLLHLEREQIAEMNSLLAANGIK
                     VYAIRPVARTLEDQFLEVTGGGFIG"
     gene            1166..1948
                     /locus_tag="NLX78_RS16260"
                     /old_locus_tag="NLX78_16250"
     CDS             1166..1948
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369846.1"
                     /locus_tag="NLX78_RS16260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16250"
                     /product="ABC transporter permease"
                     /protein_id="WP_250267682.1"
                     /transl_table=11
                     /translation="MADFFKLVHNENLKIYLRVRTWIMLGLLAVITAAIPMLISLVSDQ
                     VSVWDGIALTTLFTFFLNTTFTVIVAADSVAGEFTWGTIKLLLIRPWTRSKILLSKYIS
                     VILFSLLGTIILILMVTLSSWLMLSKDAPAGSVPLFSDPISYVTLNFLYSYIALFVTMA
                     FAFMLSAVFRSSALAIGLSLFMMFTKTVYNSIGLFSTDRYEWTQYVLFTHMDLKKYLDM
                     PPGTVSSSLTFSLTVLAAYYVIFIAIAWVVFVKRDVST"
     misc_feature    2102..2118
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.86"
                     /tool="antismash"
     gene            2191..3276
                     /locus_tag="NLX78_RS16265"
                     /old_locus_tag="NLX78_16255"
     CDS             2191..3276
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426473.1"
                     /locus_tag="NLX78_RS16265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16255"
                     /product="AI-2E family transporter"
                     /protein_id="WP_254350974.1"
                     /transl_table=11
                     /translation="MLQNNRFFRLTTGIVMLLLIIYLGTKVSFIFSPLVSLVSLLVVPL
                     MLSFFLYYLFRPIVDVMERRKIKRSISILLIYLVIGVLLFVFSWGVWPTLRDQVTNLFE
                     NAPKLIKSLVDQLSQWRHNQSLRQVLPPGEDPLSQLSDTLNEAFSTLSDYSVKLVSFVS
                     YFFIVLATFPILLYYMLKEGSKFGPKMLNFFPKKYHKDALEVMEDIDSALSSFIVSRVL
                     INVALGVMMFLGFLIIGLPYALLLAVISIFLNFIPYVGAVAASIPVVIIGFLESPSMAL
                     WSLVVVIAAQQIQDNWLSPIVFGKQLDIHPLTVVILLLVGGDLLGILGIILVIPLYMCG
                     KIVIRKVYQLFLERRVEDIME"
     gene            complement(3295..3756)
                     /locus_tag="NLX78_RS16270"
                     /old_locus_tag="NLX78_16260"
     CDS             complement(3295..3756)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369848.1"
                     /locus_tag="NLX78_RS16270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16260"
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="WP_061830256.1"
                     /transl_table=11
                     /translation="MFKESKKKLSAPAMDTLLANGTSFEGTVEAEANIRIDGHFQGDIR
                     STRTVVIGESAVVRSDIIAQDVILAGKVFGSITTEGRLTITPTGELYGNTATAALVISE
                     GGVLDGTSQMNRTKDVELSTSTDESNDETQSSFSKNREDSQADLQSEAG"
     misc_feature    complement(3800..3818)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.46"
                     /tool="antismash"
     gene            complement(3802..4833)
                     /locus_tag="NLX78_RS16275"
                     /old_locus_tag="NLX78_16265"
     CDS             complement(3802..4833)
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426474.1"
                     /locus_tag="NLX78_RS16275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16265"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_023987449.1"
                     /transl_table=11
                     /translation="MKKGSLNRRMTLLVIRDAQQPPKQLQCSTAAVILVPTLVIASIST
                     LVIGLQIRSSHIISQMETNLAVQSLQMEVTVADKDAAIGRLRQEVMELTNQATNIRERL
                     QRVTELEQQMQQFIRKHGNSSATSNHKKTMTPLSWDASGHIGGELIAVHENTALLTRQA
                     MDDFQEIESLLDTVERTVPRSIQQANAVQQNLERKQAAQLLQTRRLALAEQGNPSVWPV
                     GSRRMTSSFGYRSDPFTGRSAFHSGVDIAGQTGDPVYAAGAGTVLEAASSGARGKCIII
                     QHPDGLQSWYMHLSGMQVAPGDRVHKGQTIGLLGSTGRSTGPHLHFQIVKHNQPVDPLL
                     YVQ"
     gene            4980..6410
                     /gene="cls"
                     /locus_tag="NLX78_RS16280"
                     /old_locus_tag="NLX78_16270"
     CDS             4980..6410
                     /GO_function="GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cls"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686424.1"
                     /locus_tag="NLX78_RS16280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16270"
                     /product="cardiolipin synthase"
                     /protein_id="WP_254350975.1"
                     /transl_table=11
                     /translation="MLWLLLVLIVFIFQTGTILLFEFRKPSKAVAWLFILFCFPLIGFV
                     VYYFVAQDYQKRKMVRKGGSQLFREFRERLWAQSKVIEQVEQMHNPHFKHQERLFNQLI
                     RMSENPLTGCNRTRVLTNGEETFEAMLTAMEQAQHHIHVEFYIFRADEIGRKFQEVMIR
                     KAREGVKVRFVVDGVGSYNLPYSFIRTCSEAGVEFHYFLPPFFATLDRRINYRNHRKIV
                     VVDGMIGFVGGINIGDDYLGKYPKVGFWRDTHLQIEGDSVYFLQNAFLSDWKLASGERL
                     MDVNLFPPHTCTGDEEVQILSSGPDQVWDTIQEMCFGALTVAKKRIWITTPYFIPDPGI
                     HEALKLAAVSGVDVKIIIPYQSDSKLVHLASLSYVQELLETGVEFYQYRKGFIHAKVVI
                     VDDLLGSVGTANMDMRSFFYNFELTAVVFANSALERLSADFVEDISNSSRIDLNVFRRR
                     PRSQKIAEILTRMLSPLL"
     gene            6606..7550
                     /locus_tag="NLX78_RS16285"
                     /old_locus_tag="NLX78_16275"
     CDS             6606..7550
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280287.1"
                     /locus_tag="NLX78_RS16285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16275"
                     /product="YitT family protein"
                     /protein_id="WP_081276708.1"
                     /transl_table=11
                     /translation="MSVVSKEVQNLSEITDVTGELTKISKIPANPKNKVKRLFQRAAMI
                     VVGAALMAVGLEIFLVPNGVIDGGVTGISIMASKITGYPLGIFLTLLNLPFLLIGYKQI
                     GKTFALSTLFGIVVMSIGTALLHNVSALTPGEPLLGAIFGGVILGVGVGLVIRSGGSLD
                     GTEIVAILVSEKTPFSVGEIVLFVNIFILGSAGFVFGWPNALYSMIAYYIAMKMIDITI
                     EGLDQSKSVWIISEKYRDIGDALTDRLGRGVTYLEGEGGFTGESKKVIFVVITRLEEAK
                     LKSIVEDWDPHAFVAIGNIHDVKGGRFKKKGIH"
     gene            complement(7620..8522)
                     /gene="ligD"
                     /locus_tag="NLX78_RS16290"
                     /old_locus_tag="NLX78_16280"
     CDS             complement(7620..8522)
                     /EC_number="6.5.1.1"
                     /codon_start=1
                     /gene="ligD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369853.1"
                     /locus_tag="NLX78_RS16290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16280"
                     /product="non-homologous end-joining DNA ligase"
                     /protein_id="WP_061830254.1"
                     /transl_table=11
                     /translation="MGQAVKGTITIEGQEIPITNPDKPLWPEAGVTKALYLRKLAVLAP
                     FLLKYCHHRLLTVIRWPHGIHGDFFYQKNAPRPRPDYIETALHDGIEYIVLGKLPQLLW
                     LGNQAALEFHPSLHETGSKLPCEWMIDLDPSREVEPRIMEAASIVGEVLASLGLDSVPK
                     TSGATGVQIIVPIRTGITFDELRSIGLLVGQFVTEKHPHLFTLERLKKDRGTAIYFDYL
                     QHYQGKTLAAPYTPRARPGATVSTPLTWEEVRQDVSPLDYHLLNIEERLNQVGDLIDKV
                     PPQPVEDVLKHMRTKAHRT"
     misc_feature    8668..8681
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.44"
                     /tool="antismash"
     misc_feature    8669..8682
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.35"
                     /tool="antismash"
     misc_feature    complement(8671..8684)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.74"
                     /tool="antismash"
     gene            8736..10004
                     /locus_tag="NLX78_RS16295"
                     /old_locus_tag="NLX78_16285"
     CDS             8736..10004
                     /EC_number="2.8.2.-"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309190.1"
                     /locus_tag="NLX78_RS16295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16285"
                     /product="sulfotransferase"
                     /protein_id="WP_254350976.1"
                     /transl_table=11
                     /translation="MIEKQGGGLVFLLSVPRSGSSLLTAILQNHSRLFATQEMWFLLSL
                     YDLPQSHARPYGGTGILRQFFEGMVPPDVLEQASRSYALEIYNGLLQGTTADMLIDKSP
                     RYYTVLEFIDRLFPAARRLWLIRNPLAIVASFKKVNQLRHGRFQLLEELGGPHFNMKMT
                     DITVGLFRYAHYFATPHPLAYPLRYEQLVSNPTMEIEKLCDFLGIKYELGMEKYGDFAD
                     TPKSSLFYSMGAGDPFVGEHEQAHQDSVHSWQHLLSKTEIELYCRSIGSRMFKQLGYAE
                     ELEQAEQMTGVRFEDEPDIELLSRRTQQFLQQSGFEWKVAYRMLEEQDADNRELVINAT
                     RHAAPQDPARMHVDQIVNDRRIQSLENRLAHSYEERNRLIAQLQSYQRPNQGLRYRSLF
                     SRKLGRLASVVLSSIGKEKGGRT"
     gene            10001..11926
                     /locus_tag="NLX78_RS16300"
                     /old_locus_tag="NLX78_16290"
     CDS             10001..11926
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369855.1"
                     /locus_tag="NLX78_RS16300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16290"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_254350977.1"
                     /sec_met_domain="GATase_7 (E-value: 6e-22, bitscore: 71.8,
                     seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 3.1e-27, bitscore:
                     90.0, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIAGIYSFGHESVCTEEGGKMMQALRKYPADRVCAWCEGSIFL
                     GCHAQHVTPESVHERLPFHDELRDLAITADAIIDNRSELFERLGVEQERRQDITDSELI
                     LLAYDKWGVDAAGYLIGDFAFVIWDAKEHRLYGARDMTGNRTLYIYQHDRGFAFSTVVA
                     PLLALPSLRKELYEPWLAEFLSIRAMQESVDIGTTAYKHINQLPPAHWFTMEEGKRTLH
                     KYACLDEVEPLRLKTGGEYIEAFREVFTQAVTARLRTHRAVGAALSGGLDSGAVASFAA
                     PSLHLQQKPLHAYSYVPVQDFTDWTPPTLLANERGYIQSTARYVGNIHENYMDFEGKSP
                     FSEIDIWLELMEAPYKYFENSFWIRGFYEKAQEHNVGVLLTGARGNFTVSWGPALDYYA
                     RQFRRLHWLQSFQGLWRYSKLTGRRMSHLLPVMLKKATSLESHSWLRRSNRSPVPSLIH
                     PEFAKRMHVEDIPVLSGTGWIKNADQTRKEKFSNLAIANKNGVVATKLSLRYGLWERDP
                     TGDSRVIRFCLSVPFEQYVQNGRDRALIRKAMRDHLPDDVRLNQRVRGVQPADWLHRML
                     PCWDTFMGELQLMCHDLRAAEYLNIELIKTAMAKLRHPRPEQASDPNIRLLMHSLIVYR
                     FLCGLN"
     gene            11980..12108
                     /locus_tag="NLX78_RS16305"
                     /old_locus_tag="NLX78_16295"
     CDS             11980..12108
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369856.1"
                     /locus_tag="NLX78_RS16305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16295"
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_134902123.1"
                     /transl_table=11
                     /translation="MSKKEWQEPTIEVLDISQTMAGKGWRQIDWVSDHDADIYNPS"
     gene            12300..13343
                     /locus_tag="NLX78_RS16310"
                     /old_locus_tag="NLX78_16300"
     CDS             12300..13343
                     /EC_number="2.7.1.24"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349787.1"
                     /locus_tag="NLX78_RS16310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16300"
                     /product="dephospho-CoA kinase"
                     /protein_id="WP_254350978.1"
                     /transl_table=11
                     /translation="MHDRSANVSWTKYTAFGLRIASELNLPELLLAAPEAVEDVVIRQA
                     DLTAWSGQLEQANFVMLDERFMFQIPGTAIYAVREGKEIEVSIFSGADPDTVRLFVLGT
                     CMGVLLMQRRILPIHGSAVVIGGRAYAFVGESGTGKSTLAATFRQAGYQMVSDDVIAVE
                     ATASSAIVYPAYPQQKLGLDSLLQLEALRENKHARTINHIRSLTDGNSVMPQYRDFRML
                     ADELNKYAVPAVDEFFNDPLPLGGVFELVADSPIRALMREGELVAVTEQPLNVLECLHT
                     LLQHTYRRVIIPRMGLSEWSFDTAARMARKVEGWRLLRDSSVFTASEVVQRVLDIIRKE
                     EKSYGSH"
     gene            13330..13632
                     /locus_tag="NLX78_RS16315"
                     /old_locus_tag="NLX78_16305"
     CDS             13330..13632
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309193.1"
                     /locus_tag="NLX78_RS16315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16305"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_061830251.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.7e-26,
                     bitscore: 85.4, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 7.6e-18, bitscore: 58.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGATNPAKDQYRVIYGEEVYVSDMDGEKVMMSINTGKYYNLGFTG
                     GRIWELAESGPSLGDIVTVLTNEYEVDEEQCRQQVHTFVAELEREGLLKLLRESV"
     aSDomain        13378..13611
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_NLX78_RS16315_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.20E-27"
                     /identifier="RREFam002.1"
                     /label="NLX78_RS16315"
                     /locus_tag="NLX78_RS16315"
                     /protein_end="94"
                     /protein_start="16"
                     /score="85.4"
                     /tool="antismash"
                     /translation="EEVYVSDMDGEKVMMSINTGKYYNLGFTGGRIWELAESGPSLGDI
                     VTVLTNEYEVDEEQCRQQVHTFVAELEREGLLK"
     gene            13634..14119
                     /locus_tag="NLX78_RS16320"
                     /old_locus_tag="NLX78_16310"
     CDS             13634..14119
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821220.1"
                     /locus_tag="NLX78_RS16320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16310"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_254350979.1"
                     /sec_met_domain="PF13471 (E-value: 1.4e-25, bitscore: 83.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIQRLLLLSPEVRRLLPEAWLELGWARLRQRRSFGDYSRIWGIC
                     MEETPWQCDVGQEKSIQQISHAVELASRYTPWRSSCLVQAAAAMTLLGRRKLDCTLYLG
                     TAKNAAGRLAAHAWVRSGPIYVTGKREMEAFTVVGIFGRRAVTDTNTKMADKGSSLL"
     gene            14165..15661
                     /locus_tag="NLX78_RS16325"
                     /old_locus_tag="NLX78_16315"
     CDS             14165..15661
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426482.1"
                     /locus_tag="NLX78_RS16325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16315"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_254350980.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 7.5e-82, bitscore:
                     268.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTKSVLELANWNEDQELTLLLSLLGKDFSHSQDKTAATQLREMD
                     WVRFLRLTEHHRVVPTVYLQLKTLNHPFIPAELLRNLQAQYHRNTLRMLHLQAEAGRLT
                     RLLIAHGIRVLMLKGPALAQQLYGDVSLRTSKDIDLLIAPDDMDEAEHWMKEAGYASKS
                     GEVRVLGSWKWKDHHASYLHPQKRVEIELHWRLHPDGGGEPSFDELWSCRQMGKATGAS
                     RMVPLAPADNRTAMTSCMYTLGSEHQFLYLSAHGARHGWFRLRWLVDIDRLAACAVDWE
                     ALLPMMRRYGGLPAGGQAWALAAALLGTPIPEPMRPVSATRQAHRLALSALAFMQASVP
                     APYPIAHGSGTGRLAPSELLRSRALAEQAEAAPLDGGPSLCSTCGEAAMLATIGVTSIT
                     EGDSNDDYSPMSTATSCAPITPAAASSQVMTRNTAAAHQPVSRTYLLSLKEPRHRLSYL
                     ISRLFPSTGDSAVFPLPRQLHFLYIPLRPFLWLKRRFSKH"
     gene            15682..17493
                     /locus_tag="NLX78_RS16330"
                     /old_locus_tag="NLX78_16320"
     CDS             15682..17493
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821218.1"
                     /locus_tag="NLX78_RS16330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16320"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_254350981.1"
                     /transl_table=11
                     /translation="MVHLRLYMTKLYSVNGGALFLNIGCMIIVSLLEGFGIYMLVPMLA
                     AIGVFVGHSGMPFLSDGLDHFLAFIPKSWLLPGMLMVFVVLLTGQALLQRYQSILNSRI
                     QQRFMRSLRVDVYTSFMKAQWAFYLRQRKSDFSHVMTTELARVSQGTNLLLQLTTAVMF
                     TLIQIALAFWLSPSLTGLVFLSGLGLFVVFRRSIRNAKQLGDRTTELSQVYFAGITDHM
                     NGMKDIKSNLLEAANIHWFRSLTQRMEDNTTQFVRQNATTQFFHRTAAAVFVACVIFIS
                     LQWLHVTSEKLIVLILIFSRLWPRFALIQASLEYIMSMISAFESVTKVQQECEAFSDPS
                     VFKLSSASVRQPLSLRHGIECSHLGYRYDGAAEPALHRINLFIPARGMTAIVGKSGAGK
                     STMVDVLMGFLRPTGGRITIDGLVLDDELLPQWRQSFGYVSQDPFLFHATVRENLMLAD
                     KDASEQQLWEALHFAAADSFVSRLPEGLDTVIGDRGIRLSGGERQRLVLARAVLHHPPV
                     LILDEATSALDGEHEAAIQAALERMKGQMTLIVIAHRLSTIRHADQIVVLDQGEVIQQG
                     NYRQLEQEERGAFSQLLSYQSSLTATP"
     gene            complement(17516..18430)
                     /locus_tag="NLX78_RS16335"
                     /old_locus_tag="NLX78_16325"
     CDS             complement(17516..18430)
                     /GO_function="GO:0045027 - DNA end binding [Evidence IEA]"
                     /GO_process="GO:0006303 - double-strand break repair via
                     nonhomologous end joining [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309197.1"
                     /locus_tag="NLX78_RS16335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16325"
                     /product="Ku protein"
                     /protein_id="WP_013309197.1"
                     /transl_table=11
                     /translation="MHTVWKGAISFGLVHVPVKMFSATEDKDISMRYIHKECGSPLSYV
                     RKCPVCDKEVEWEEIGKGYEYEKGKFVMFDKEELEQVSGQADKNIVILDFVDLQEIDPI
                     YFQKTYYLSPDQAGSNAYKLLMNAMKDTGKIGIAQISIRSKSSLAAIRVLDECLAVETM
                     FYPDEIRPIAQVPNLPGQEEVKEKELTMAKMLIEQLSTPFDAAKYTDQYRERLLDLIQH
                     KVAGEEVRIAPTQPQTNVVDLMAALQASIEAVQPVVTDPGPAAKKRPARKPAAPTAQQA
                     VAGENISPTPVKKKRSTAKRKET"
     gene            18641..18880
                     /locus_tag="NLX78_RS16340"
                     /old_locus_tag="NLX78_16330"
     CDS             18641..18880
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369863.1"
                     /locus_tag="NLX78_RS16340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16330"
                     /product="hypothetical protein"
                     /protein_id="WP_061829618.1"
                     /transl_table=11
                     /translation="MSGKSFPRQIRHRVGQNHVAFRGPAGGEQDALPPEFALSHGIQPP
                     FPIAVAHVDLEAVVSTSPSHSIPSLDVERIIDED"
     gene            18937..19116
                     /locus_tag="NLX78_RS16345"
                     /old_locus_tag="NLX78_16335"
     CDS             18937..19116
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309199.1"
                     /locus_tag="NLX78_RS16345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16335"
                     /product="H-type small acid-soluble spore protein"
                     /protein_id="WP_013309199.1"
                     /transl_table=11
                     /translation="MNVERAKAIYDSPDTIAVQLDGKPIWIEHVDEANGMATVQIGSRP
                     TNTQTVRVDRLEEQ"
     gene            complement(19362..20018)
                     /locus_tag="NLX78_RS16350"
                     /old_locus_tag="NLX78_16340"
     CDS             complement(19362..20018)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369865.1"
                     /locus_tag="NLX78_RS16350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16340"
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="WP_165176411.1"
                     /transl_table=11
                     /translation="MNNREFIARRIAQEFKNGEVVNLGVGLPTMVVDYIPEDIHIMLQA
                     ENGILGVGPKAAQGKERLDCIDSGGNYVTTMEGACFFDSALSFSIIRGGHVDITVLGAL
                     EVDEKGNLASWMIPGKKVPGMGGAMDLVVGAKRVIVAMEHVNKNGAPKILEQCKLPLTA
                     VNVVKTIVTEKAVIDVIPGQGLMLKEIAPGLSVEDVQLATEAKLMVSPHLRAIAV"
     gene            complement(20015..20680)
                     /locus_tag="NLX78_RS16355"
                     /old_locus_tag="NLX78_16345"
     CDS             complement(20015..20680)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429861.1"
                     /locus_tag="NLX78_RS16355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16345"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_235307615.1"
                     /transl_table=11
                     /translation="MNNKVISAEEAVKKVKDGDTVMVGGFLAGGFPEDLVRALVDTNPA
                     SNLTIVSNDTGTPELSIYKLVKSGRVKRIFASYIGSNPETGRLLMTKEAEVQLFPQGTL
                     AEKIRAGGAGLGGVLTPVGVGTVVEEGKQKIKIDEKEYLLELPLKADVALIRAHKADEA
                     GNLVINGSSRNFNMVMATAAEYVVAQVDEYVKTGEIDPNHVNVPGIFVDAIVKVGENA"
     gene            complement(20722..21462)
                     /locus_tag="NLX78_RS16360"
                     /old_locus_tag="NLX78_16350"
     CDS             complement(20722..21462)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686439.1"
                     /locus_tag="NLX78_RS16360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16350"
                     /product="acetoacetate decarboxylase"
                     /protein_id="WP_254350982.1"
                     /transl_table=11
                     /translation="MNQKDVLSLQSMPAASGSYGRPPYRFINREFFIITYETDPAAIRQ
                     AVPEPLEPDGSNTVSYEWIKMPDSSGLGCYEESGIVIPCTFQGEPCNFVAQMYLDNAPA
                     ILGGREVWGFPKKWAKPRLSVEETETLTGTLHYNHVLVATGTMPFKYNILDEKETAKAI
                     AKTQVNLKLIPDVDGTPKIAQLVAYNLENITVKGAWSGPARLSLIPHVNAPVADLPVKA
                     YIGGKHFIADLTLPYGSVLYDYLQ"
     misc_feature    complement(21512..21528)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.67"
                     /tool="antismash"
     gene            complement(21518..22702)
                     /locus_tag="NLX78_RS16365"
                     /old_locus_tag="NLX78_16355"
     CDS             complement(21518..22702)
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429859.1"
                     /locus_tag="NLX78_RS16365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16355"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_134902140.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 7.7e-07, bitscore:
                     22.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVALVSPLRTAVGSFNKTLAPLSASELGATVMTACLQQSKLEP
                     SLIDQIYLGNVLQAGNGQNPARQAALKAGIPIDVPETTINTVCGSGLHAVALAYNSILA
                     EQGNIVLAGGMESMSNAPYLLRNARNGYKLGNGELVDSLVADGLTCPINHYHMGITAEN
                     VAEKYGISRLEQDEFAYQSQLKAVEAKNKKLFEEQIVPVMIKTKKETISFTEDEHIRGN
                     TTQEKLSQLKPAFKENGTVTAGNASGINDGAAAVLVVSEDKCKEHALKPLAYIKGYSLV
                     GVDPAYMGMGPVKAISTLLKQQGISIDAIDLFEINEAFASQALAVVKELGVSPEKVNVN
                     GGAIAIGHPVGASGARILTTLVHEMVRRSSRYGIASLCIGTGMGIAMLVENALI"
     misc_feature    22694..22707
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.09"
                     /tool="antismash"
     misc_feature    22881..22896
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.33"
                     /tool="antismash"
     misc_feature    22883..22897
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.27"
                     /tool="antismash"
     misc_feature    23021..23035
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 24.83"
                     /tool="antismash"
     misc_feature    23028..23042
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.75"
                     /tool="antismash"
     misc_feature    complement(23029..23044)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.84"
                     /tool="antismash"
     misc_feature    23051..23064
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.68"
                     /tool="antismash"
     misc_feature    complement(23052..23065)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.79"
                     /tool="antismash"
     misc_feature    complement(23053..23066)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.29"
                     /tool="antismash"
     gene            complement(23314..23844)
                     /locus_tag="NLX78_RS16370"
                     /old_locus_tag="NLX78_16360"
     CDS             complement(23314..23844)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429259.1"
                     /locus_tag="NLX78_RS16370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_16360"
                     /product="cysteine hydrolase family protein"
                     /protein_id="WP_061829613.1"
                     /transl_table=11
                     /translation="MGQTVLLMIDVQQAMFMYDEKLYREQEVVAHLQQLLDKARATGTP
                     VIFVQHTDEADEDFRENSVGWAIADVVRPLPHERIVRKSSWDSFYQTELGHVLKELGAD
                     QLVIAGMQTEFCLDTTCRSAYSLGYQNNVLVLDAHSTFDSKVLSGEQIVAHHNGMLGNR
                     FVRLLATEDVHFS"
ORIGIN
        1 aggagttagg gaaggtttac cgtattacgg tcactcagca ttacaagacc cgattcggta
       61 attttgatat cgtacagcct tgttatgtga cacaggaaga tgagaaatgg cgggtgcttt
      121 ggatatacaa ggacaaggaa tagaggctgc gtggtgtttc taaaaggtta aatatggtac
      181 aatacttcca aaaccggaaa tgtaaagtaa aatggataac agcttcactc cggatggaag
      241 gagtttcata gtatgcagca agcgacagga caggttcccg tcatacgtat ggagggtgtg
      301 agtaaaatca tttcctcaaa agcgatcgtg gatgatctga cgctggaggt tccggcggga
      361 caggtatttg gtttcctcgg acccaatggt gcgggaaaaa cgactaccat ccgtatgatg
      421 gttggcctga tttcgatcag caagggcgat attcatattt gtggagacag cattaatacc
      481 gattttgaaa aggccgtttc ccatgtcggc gcaattgttg agaacccgga gatgtacaag
      541 tttttgacag gctatcaaaa tttgcagcat tttgcgcgaa tgtctcctgg ggtgacccaa
      601 gagcgcgtgg atgaagcgat tcgtttggtg ggactcggaa accgaattca tgacaaagta
      661 aaaacctact cgctcgggat gcggcagcga cttggggtag ctcaggcgat tttgcatcga
      721 ccgaagctgc tcgtgctgga cgagccgacc aacggcttgg acccgcaggg tattcgagaa
      781 ctgcgggatt atttgcgtca attgacccgt acggaaggaa ttaccgtgtt cgtatcaagc
      841 catttgttgt ccgagatgga gctgatgtgc gaccgtgtag ccattattca gagcggacgg
      901 ctggttgata tcaagcagct gaagaataca ggggaggaag tgcagacggc agaaattgct
      961 tttgaggtaa atgatgccga gcaagcttat gcgcttgctg gagcagggcg cgtcgaaggc
     1021 aatcaactgc tgcttcactt ggagcgggaa cagatcgcag agatgaacag cctgctggct
     1081 gcaaacggaa ttaaagtata tgcgattcgc ccggttgccc gtacgctgga agatcaattt
     1141 ttggaagtga cgggaggcgg gttcattggc tgattttttc aagttggtac ataacgaaaa
     1201 tctgaaaatt tacctgcgtg tgcgcacatg gattatgctg ggtctgctgg cggtcatcac
     1261 ggctgcgatt ccgatgctga tttccctggt ttccgatcag gtcagtgtgt gggatggaat
     1321 tgcgttgacg acgttgttta catttttcct caatacgacg tttacggtca ttgtagccgc
     1381 tgattcggtg gctggtgaat ttacttgggg aacgattaag ttgttgctca tccgaccttg
     1441 gactcgcagc aaaatattgt tgtccaagta tatatccgtg attttgttca gtttgctcgg
     1501 aacgatcatt ttgatcttga tggttacgct gtcctcatgg ctgatgttat ccaaggatgc
     1561 accagcgggt tctgttccgc tgttcagtga tccgatatct tatgtaacgc tgaacttctt
     1621 gtatagctat atcgccttat tcgtgacgat ggcctttgca tttatgctat ccgcagtttt
     1681 ccgttccagt gccttggcga ttgggctgtc gttgttcatg atgttcacca aaacagtcta
     1741 taactctatt ggcttgttca gcacagatcg ttatgaatgg acccaatacg tactatttac
     1801 acatatggat ctgaaaaaat atctagatat gccgccggga acagtaagtt ccagtctaac
     1861 cttttcgctc accgtgctgg ccgcctatta tgtgattttt atcgccattg cctgggtggt
     1921 tttcgtaaaa cgggatgttt cgacctaaat ggaagtgcca tagagtaaca caaaggacgt
     1981 tcaaatgcct agcatttgga cgtccttttt attatttcag gaatttgcaa aatattcatt
     2041 ttacgctatt ttatcctgta tctatgttat ttttgctgca cattctgagt gtaggggtat
     2101 attgtaatct attttcagca acaatcaatc aatagggtca ttttgcgttt aaagaggtag
     2161 agagaacaga acagaggggg gccgcatgat atgctgcaaa ataatcgttt ttttcgtctg
     2221 actactggta ttgtcatgct attactcatc atttacttgg gtaccaaagt aagctttata
     2281 ttcagtcctc tcgtatcttt ggtcagcttg ctggttgtac cgttgatgct atcttttttc
     2341 ctctattatt tattcaggcc gattgtagat gtaatggaac gtagaaaaat caaacgatct
     2401 atctccatct tgctgattta tttggtcatt ggagtgttat tgtttgtttt ctcatggggt
     2461 gtgtggccta cgctgcgtga tcaggtaacc aatttatttg aaaatgcgcc gaagctcatt
     2521 aaaagtctgg ttgatcaatt gagccaatgg cggcataatc aatccttgag acaagtgctg
     2581 cctccgggtg aagacccgct gtcacaactg tcagatacgt tgaacgaagc tttttcgaca
     2641 ctgtctgatt actcggtaaa gctggtatcg ttcgtatcct acttttttat cgtattggct
     2701 acttttccta tattgctcta ttacatgttg aaggaaggga gcaagtttgg ccctaaaatg
     2761 ctaaacttct ttcctaaaaa atatcacaaa gacgcgttgg aggtcatgga agatatcgat
     2821 agcgcgctta gcagctttat cgtgagtcgg gtgctgatca atgtcgcgtt gggtgtgatg
     2881 atgttccttg gatttttaat tattggtttg ccttatgcct tgctgctcgc cgttatttcg
     2941 atttttctta attttattcc ctatgtgggg gcagtggctg cttctatacc tgtagttatt
     3001 attggatttc tcgaatcacc ttcgatggcg ctctggtcgc tggtcgtggt gattgctgca
     3061 cagcaaattc aggataattg gctgtcacct atagtttttg gcaaacagct ggatattcat
     3121 ccgttgactg tcgttatttt actgttggtt ggtggcgacc tgctcgggat tctgggcatc
     3181 attttggtga ttccattgta tatgtgcgga aaaattgtca tacgtaaggt gtaccaatta
     3241 tttttggaac gcagagtgga ggatattatg gaatgaatgg agtgtatact gattttatcc
     3301 tgcttcggat tgcagatcgg cttggctgtc ctccctgttt ttgctgaaac tagattgggt
     3361 ttcgtcgttt gactcatccg tagaagttga caactctaca tcctttgttc ggttcatttg
     3421 acttgtgccg tccagtacac cgccttcaga tatgaccaat gcagcggtcg ccgtatttcc
     3481 gtacagttca cctgtcggcg taatggtcag tcgtccttct gtagtaatgc tgccgaacac
     3541 cttaccggca agaatgacgt cttgtgcgat gatgtccgaa cgtaccacag cagattctcc
     3601 aatgacgaca gtacgagtgc tgcggatatc gccctgaaaa tgaccgtcaa tccgaatatt
     3661 ggcctctgcc tcaactgtac cttcaaagct ggtgccatta gcgagcagtg tatccatagc
     3721 tggggcggag agcttttttt tggattcctt gaacatgatg gttttccccc aatcttttat
     3781 tgtaaggatt ttgaaaagtc ctcattgtac atacagtaat ggatcgacag gttggttatg
     3841 cttgacgatc tgaaaatgaa gatgaggtcc cgtgcttctc ccggtacttc ctaacagacc
     3901 gatggtctgt cctttgtgga cacgatctcc cggagccacc tgcatgccgc tcaggtgcat
     3961 ataccagctc tggagtccgt caggatgctg gatgatgatg cacttgccgc gggctccgct
     4021 agaagcagcc tccaagacgg tacctgctcc tgctgcatag actggatcac cggtttgtcc
     4081 ggcaatgtcc acgcctgaat gaaaggcaga tctacccgta aaagggtcgc tgcgatagcc
     4141 gaagctggag gtcattcgcc gtgaacctac aggccaaacg gagggattcc cttgttcggc
     4201 aagagccagc ctacgggtct ggagtagctg tgcggcttgt ttgcgctcca gattctgctg
     4261 tacggcattt gcttgctgaa tagagcgggg aaccgtacgt tccaccgtgt ccaacagaga
     4321 ttcgatctcc tgaaaatcat ccattgcctg gcgagttagg agggcagtat tttcatgcac
     4381 tgcgatcagt tcacctccaa tatggccgga agcatcccag gagagcggcg tcatggtctt
     4441 tttatggtta cttgtggcag atgagtttcc gtgtttacga atgaattgct gcatttgttg
     4501 ttccagctct gttacgcgct gaaggcgttc acgaatattg gtggcttgat tcgtcagctc
     4561 catgacttcc tgccgtagtc gcccaatggc tgcatccttg tccgctaccg tgacctccat
     4621 ctgcaaactc tggacagcaa gattcgtttc catttgggag ataatatggg aagaacggat
     4681 ttgcagcccg atcacgagtg tagagataga cgcgatcaca agagttggga cgagaatgac
     4741 agcggctgta gagcattgta gctgcttggg cggttgctgt gcatcccgaa taacaagcag
     4801 ggtcatccgg cgatttaggc ttcctttttt cataatcgct cctttccgga catcgctcct
     4861 atagtgcttg gttactatct attcagctta agaggcaaac atgtcaaaaa aattggagct
     4921 tagtataaaa cgtagatgag gattttgcaa aatcctaaga tatataagga ggcttagaca
     4981 tgctgtggtt gctgttggtt ttaattgttt ttatttttca gaccgggacg atcctgctct
     5041 ttgaatttcg caagccgtcc aaagcggtag cctggctctt tattttgttt tgcttcccgc
     5101 tcattggctt tgtcgtgtac tactttgttg cacaggatta tcagaagcgc aaaatggtcc
     5161 gaaaaggggg atcgcagctg tttcgtgaat ttcgcgagcg tctgtgggcg caatccaaag
     5221 tgattgaaca ggtggagcaa atgcataatc ctcatttcaa gcatcaggag cgcctgttta
     5281 accagttaat tcgcatgtcg gaaaacccgt tgactggatg taatcgcaca cgtgtgctga
     5341 cgaacggtga agaaaccttc gaggctatgc tgacagcgat ggaacaagcc caacatcata
     5401 tccatgtgga gttttacata tttcgggccg atgaaatcgg aagaaagttt caagaggtca
     5461 tgatccgcaa ggcacgtgag ggagtaaagg tacgattcgt tgtggacggt gtaggaagct
     5521 acaatttgcc ttattccttt attcgtacct gtagtgaggc gggagtggaa tttcattatt
     5581 ttctacctcc gtttttcgcc acgttggatc gccggatcaa ctatcgcaat cacaggaaaa
     5641 tcgtggtggt ggacggcatg attggatttg tgggtgggat taatataggc gacgattatc
     5701 tcggaaaata ccccaaagtg ggtttttgga gggatacgca tttgcagatt gaaggagata
     5761 gcgtctattt tctgcaaaat gcatttctta gcgactggaa gctggcctca ggggagagat
     5821 tgatggatgt gaatttattt cctccacata cctgcaccgg ggatgaggaa gtacagattt
     5881 tgagcagtgg tcccgatcag gtatgggata cgattcagga aatgtgtttt ggtgcgctca
     5941 cggttgccaa aaagcggatt tggattacga cgccgtattt tattcccgat ccggggattc
     6001 atgaggcgct caagctggca gcagtcagtg gcgtagatgt gaaaattatt attccctacc
     6061 aatctgattc gaagctggtt catctggcgt ctttatccta tgtgcaagaa ttgttggaga
     6121 caggggtgga gttctaccaa tatcgaaaag gatttattca cgccaaagtg gtgattgtcg
     6181 atgatttact cggctcggtc gggaccgcca atatggacat gcgcagcttt ttctataatt
     6241 ttgagttgac cgctgtagtt tttgctaatt cagcgctgga acggctttcg gcagattttg
     6301 tagaggacat ttccaactcc tcacgcattg atttgaacgt gttccgcaga cggcctcgat
     6361 ctcagaaaat agctgaaatt ctaactcgca tgctctctcc actcctttaa aggcgatttt
     6421 cgccgttttt atcgctataa tcccgcttta ttgtgattta tgtgctcttt gctaactttt
     6481 ttgcgcaaaa tcgcagtttt atggtatact attcatataa cacaagcgcg gtaaaggaga
     6541 ggggactgcg gatagcagcc cctttttcgg tccaatatac catactgtaa cggggggatt
     6601 tatatatgag tgtagtgagc aaggaagtcc aaaatctgtc tgagatcaca gatgtgaccg
     6661 gagagttgac caagatcagc aaaattccag ctaatccgaa gaacaaagta aaacgcctgt
     6721 ttcagcgtgc agccatgatt gtggttggtg ccgctttgat ggcagtggga ttggaaatat
     6781 ttctggttcc taacggcgtt attgacggag gcgttacagg tatttccatc atggcctcca
     6841 agattactgg ctatccgctc ggtattttcc tgaccctgtt gaaccttcca tttttactta
     6901 tcggctacaa acaaatcggt aaaaccttcg ctttatccac attattcggt atcgtcgtta
     6961 tgtccatcgg aaccgcgtta cttcacaatg taagtgcatt gactcctggc gaaccgctgc
     7021 tcggcgctat ttttgggggc gttattctcg gtgttggggt gggtcttgtg attcggtccg
     7081 gcggctcgct ggatgggaca gagatcgtag ctattctcgt cagtgaaaaa actccttttt
     7141 cggtcggtga gatcgtactg ttcgttaata tcttcattct gggaagtgca ggttttgtgt
     7201 tcggttggcc aaatgccctg tattccatga ttgcttatta tatcgccatg aaaatgattg
     7261 atattacgat tgaaggtctg gatcagtcca aatcggtctg gattattagt gaaaaatacc
     7321 gtgatatcgg ggatgccctg acagaccgtc ttggacgggg cgtcacttat ctggaaggtg
     7381 aaggcggctt tacgggcgaa agcaagaaag tgattttcgt cgtcattacc cgactggagg
     7441 aagcgaagct gaagagcatc gttgaagatt gggacccgca cgctttcgtt gcgatcggta
     7501 acattcacga tgtgaagggc ggacgtttta agaaaaaagg aatacactag cgcaagggga
     7561 caatttctca gcctaatggc tgcggggttc gtcccctttt ttgttcttcc aagcatggat
     7621 caggttcggt gtgccttggt gcgcatatgc ttgaggacgt cttctacggg ctggggagga
     7681 accttgtcga tcaagtcgcc tacctggttt agtcgttcct caatattcag caaatggtag
     7741 tcaagtggtg atacatcttg ccttacctct tcccaggtta gcggagtaga gaccgtagca
     7801 ccggggcgtg cccgcggggt ataaggagcg gccagagttt tcccctgata atgctgcaag
     7861 taatcaaaat agatggctgt tccacgatcc ttctttaacc gttcgagtgt gaacagatgc
     7921 gggtgctttt ctgtcacaaa ctgcccgact aatagcccga tgctgcgaag ttcatcgaag
     7981 gttatgcctg tacggatcgg aacgataatt tgtacacctg tagccccgga tgttttgggg
     8041 acggaatcca aaccaagcga agccagtact tcaccgacaa tagaggcggc ctccataata
     8101 cgtggctcca cctctctgga tggatcaaga tcaatcatcc attcacaggg cagcttgctt
     8161 cccgtttcat gcagagaggg atggaattcc aacgcagcct gattaccaag ccagagaagt
     8221 tgtggcaatt tgccgagcac gatatattca attccgtcat gcagagcggt ttcaatatag
     8281 tccgggcgag gacgtggggc atttttttgg taaaaaaaat caccatgaat cccatgtggc
     8341 cagcggatga cggtcagcag acgatgatgg caatatttga gcaggaaggg agccaatacc
     8401 gcgagcttgc gaagatatag cgccttagtc acgcctgctt caggccacag cggtttatct
     8461 gggtttgtga taggaatttc ctgaccttca atggtaattg tacctttaac agcttgtccc
     8521 atagtgctat cctcctttgg ctaatatgca ggaaatcttt atttacaggc tgattgttga
     8581 gctcatagat ctacatatgg tttaacatga acgtgaagtg ctgaatttat ccatcaaagg
     8641 gattgacaag atacattatg tatcataaat ttataataaa aaatacgata tgtatctatc
     8701 aaaatgtctt gagcagaggt agaggaggag tttgcttgat tgaaaagcaa ggcggagggc
     8761 tggtattcct gttaagtgtc cctcggagtg gaagctcgct gcttaccgcc attttgcaaa
     8821 accattcccg cctgtttgcc acgcaggaaa tgtggtttct gctcagttta tatgatcttc
     8881 ctcagtcaca tgcacggcca tatggaggaa cagggatact tcggcaattt tttgaaggta
     8941 tggtcccccc cgacgtattg gagcaggcct cccgttcgta tgcacttgaa atatataatg
     9001 gtctgcttca aggaacaaca gcagatatgc ttatcgacaa atccccgcgt tactatacgg
     9061 ttttagaatt tatagaccgt ttattccctg ctgcccgcag gctgtggctt atccggaatc
     9121 ctttggccat tgtggcctca ttcaaaaagg ttaatcagct acggcatgga cgttttcaac
     9181 tgctggagga actggggggt ccgcatttta atatgaaaat gacggatatt acggttggtt
     9241 tattccgtta tgctcattat tttgctacac ctcatccact tgcatacccg cttaggtatg
     9301 aacaactcgt atccaatcca acgatggaga tcgagaagct gtgcgatttt ctgggaatca
     9361 agtacgagct ggggatggaa aagtacgggg actttgcgga tacgcccaaa tccagtcttt
     9421 tttatagtat gggagcgggt gatcccttcg taggagagca tgagcaggcg catcaagatt
     9481 cggtacatag ctggcaacac ttgttgagta aaacggaaat tgagctgtat tgcagaagca
     9541 ttgggtcccg catgtttaag cagcttggtt acgcggaaga gctggagcag gctgagcaga
     9601 tgactggagt ccgctttgaa gatgagccgg atatagagtt gctgagtcga cgtacacaac
     9661 aattcctcca gcaaagcggc tttgaatgga aggtagctta tcggatgctg gaagaacagg
     9721 atgcagataa cagagaactc gtgataaatg caacccgtca tgctgcacct caagatccgg
     9781 caaggatgca tgtggaccag atcgtgaacg atcggcggat tcaatccctg gaaaacaggt
     9841 tggcacatag ctatgaggag cgaaaccgtc ttatagctca gctccaaagc tatcaacgcc
     9901 caaatcaagg tctccgatat cgcagccttt tttcccgtaa gctcgggcgc ttggcgtctg
     9961 tagtgttatc aagtatagga aaagaaaaag ggggaagaac gtgagtgcga ttgccggaat
    10021 ctatagcttt gggcatgagt ccgtatgcac cgaagaaggc gggaaaatga tgcaagctct
    10081 gcgaaaatat cccgctgacc gcgtatgcgc ttggtgtgaa ggctctattt ttttgggttg
    10141 tcatgcccag catgtgaccc cggaatctgt tcatgagcgt cttcccttcc atgatgagct
    10201 aagagatttg gcaatcacag cggatgcaat tattgacaac cgttccgagc tgtttgaacg
    10261 gctgggagtt gagcaggaac ggcgacaaga tatcacggac agcgagctga ttttgctggc
    10321 atatgacaaa tggggagtgg atgcagccgg ttatctgata ggtgattttg cctttgttat
    10381 ttgggatgcc aaggaacatc gattatatgg tgctcgagat atgacaggca atcgtacgtt
    10441 gtacatctac cagcatgacc gaggattcgc gtttagcacg gtagtcgctc cgcttttggc
    10501 cctgccctct ctgcgaaaag aattgtatga gccatggctg gccgaatttt tgtccatccg
    10561 agccatgcag gaatccgtcg atatcggaac gaccgcatac aagcatatca accagcttcc
    10621 tcctgcacat tggttcacga tggaggaggg aaagcgaacc cttcataaat atgcatgtct
    10681 ggatgaggta gagccactgc ggctcaaaac agggggcgag tacatagaag ctttccgcga
    10741 ggtgttcaca caagcggtca ctgcccgact acggacgcat cgcgctgtag gggctgccct
    10801 aagtggaggg ctggattctg gagcggttgc cagctttgcc gcaccatcgc tgcacttgca
    10861 acaaaagccg ctgcatgcct acagctatgt gcctgttcaa gattttacag actggacacc
    10921 gcctacattg ctggcgaacg aacgaggcta tattcagtct acggctcgct atgtgggcaa
    10981 cattcacgag aattatatgg attttgaggg gaaaagtccg ttttcagaaa ttgatatttg
    11041 gctggaactc atggaagcac cctacaaata ttttgaaaac tccttctgga tcagaggttt
    11101 ttacgaaaaa gcacaggagc acaatgtcgg tgtactgttg accggggcac gaggcaactt
    11161 taccgtatcg tggggccctg cactagacta ttatgcccgg cagtttcgtc gtttgcactg
    11221 gttgcaatcc tttcagggat tgtggcggta cagcaagctt acgggcaggc gtatgtcaca
    11281 tctactcccc gtaatgttga aaaaagcgac ttcacttgaa tctcattcat ggttgcggcg
    11341 tagcaatcga agtcccgttc cttccctgat tcacccggag tttgccaaac ggatgcatgt
    11401 agaagatatt cctgtattga gcggaacagg ttggataaaa aatgccgatc agacgagaaa
    11461 agagaagttc tcaaatttgg cgattgccaa caaaaatggt gtggttgcga ccaaactttc
    11521 actacgttat ggcctatggg aacgtgatcc gaccggggac agccgggtaa ttcgtttttg
    11581 cttatcggtg ccttttgagc agtatgtgca aaacggtcgg gaccgtgccc tcattcgtaa
    11641 agccatgcgt gatcatctac ctgatgatgt tcggttgaac cagcgggtac gcggcgtgca
    11701 gcctgccgat tggctacatc gtatgcttcc ttgctgggat acgtttatgg gggagcttca
    11761 actgatgtgt catgatttac gagcggctga atatctcaat attgagttaa taaagacggc
    11821 tatggcgaaa cttcgccacc cccgccctga acaggcgtct gatccaaata tacgactact
    11881 aatgcatagc ctgatcgtgt accgttttct ctgtggattg aactgattca gattgatctg
    11941 gccggacagt tcgtcattcg ttggagggga ggtgatgaaa tgagtaaaaa agaatggcag
    12001 gaaccgacga tagaggtgtt ggatattagc cagaccatgg cggggaaagg ctggagacag
    12061 attgattggg tgtccgacca cgatgccgat atttataatc caagctaata gatggttata
    12121 catgcagccg atgttggact ggaagccagt cagctcggcc cataacgatt gaatgaacga
    12181 aaatagcaca atccattgga ctcgtattca atacagagcc gtctttattt ctttcgggtt
    12241 agagattttg cccaagaaat aaagacggga tttttaagga cagaggagtg agtcctaccg
    12301 tgcatgacag gagtgcaaat gttagttgga cgaaatatac agcctttgga ctcaggattg
    12361 ccagtgaact gaatctgcct gagctgctcc tggcagcacc ggaagcagta gaggatgtag
    12421 tcattcgaca ggctgatttg actgcatgga gtggtcagct ggaacaggcc aattttgtga
    12481 tgctggatga acgatttatg ttccaaatac caggcacggc catttatgcc gtcagggaag
    12541 gcaaggaaat cgaggtaagc atattctccg gggccgatcc tgacaccgtg cggctatttg
    12601 tactgggtac gtgcatgggt gttctgctga tgcaaagacg aatattacct attcacggaa
    12661 gtgcggtcgt cattgggggg agggcctacg catttgtggg tgaatcgggg acggggaaat
    12721 cgacactggc ggctactttt aggcaggcag gttatcagat ggttagtgat gacgtgattg
    12781 ctgtagaagc tacggcttcc tcagccatcg tgtatccagc ttatccgcag caaaagctgg
    12841 ggttggatag cttgctccaa ctggaggctt tacgggagaa caagcatgca cgcacaataa
    12901 atcacatacg gtccctaacg gatggcaatt ctgtaatgcc acaatacaga gattttcgta
    12961 tgcttgcaga tgagctgaat aaatatgccg tacccgccgt agatgaattt tttaacgatc
    13021 cgctgccctt aggaggcgta tttgagctag tggcagattc accaatccgt gcgttgatgc
    13081 gcgaagggga gttagtggca gttacggaac agcccttgaa cgttctggag tgcttgcata
    13141 cattactaca acatacatat cgtagggtga ttattccgcg aatgggtttg agtgaatggt
    13201 cgtttgatac agcggctagg atggctcgta aagtagaggg ctggcggctg ctgagggata
    13261 gttccgtctt tactgcgtcc gaggttgtac aacgggtact tgatatcatt cgtaaggagg
    13321 aaaagagtta tgggagccac taatccagct aaagatcagt atcgcgtcat ttacggtgaa
    13381 gaggtctacg tcagtgatat ggacggggaa aaagtgatga tgagtattaa cactggtaaa
    13441 tattacaact taggcttcac aggaggacga atctgggaac tggcagaatc cggtccttca
    13501 cttggcgata tcgtaactgt cctgacgaac gaatatgagg tggacgagga acagtgcaga
    13561 cagcaggtac atacctttgt ggctgagttg gagcgggaag gactgttaaa gcttctacgg
    13621 gagtcggtat aatatgcgga tacaacggct tcttctcctg tctccagagg tcaggagatt
    13681 gttgccggaa gcttggctgg agctgggatg ggcgaggctg cgccagcgtc gttcttttgg
    13741 ggattactca aggatttggg gcatatgtat ggaagaaact ccatggcagt gtgatgtcgg
    13801 gcaggagaag tccattcagc agatttcgca cgctgtggag ctggcaagcc gttatactcc
    13861 ttggcgcagt agttgtcttg tacaagccgc tgcggcgatg acgttgctgg gacgtagaaa
    13921 actggactgc acgctgtatc tgggcacagc caaaaatgcc gctggccgct tggccgcaca
    13981 tgcatgggta cgtagcggac cgatttatgt cacggggaaa cgggagatgg aagcatttac
    14041 ggtggtgggg atattcggga gacgtgctgt gacggataca aatacaaaga tggcagataa
    14101 aggtagttct ttactttaag gcgatgagac aaaagaagtc caaagaatcg aaggagaaga
    14161 atgcatgccc accaagtctg ttttggaact tgcgaattgg aatgaggatc aggaattaac
    14221 gttgttactc tctctattgg ggaaagactt ttctcattcg caggataaga ctgctgctac
    14281 ccagctgcgt gagatggatt gggtccgctt tttacgtctg accgagcacc atcgagtggt
    14341 acctacggtg tatctccaac tgaaaacatt gaatcatccg ttcattcccg cagaattgtt
    14401 gcgaaacctt caggcgcaat atcatcgaaa cacgcttcgc atgctccatc ttcaagcaga
    14461 agccgggcgt ctgaccaggc tgctcatagc tcatggaatc cgtgtgctta tgctgaaggg
    14521 tcctgctctg gcgcagcaat tgtacgggga tgtttctctg cgtacctcca aggacatcga
    14581 tttactcatt gcccctgacg atatggatga ggctgagcat tggatgaagg aagccggata
    14641 tgcgtccaag agcggggaag tgcgtgtcct tggcagttgg aaatggaagg accatcatgc
    14701 atcctacctc catccgcaaa agcgggtaga gatagagttg cattggcgtc ttcacccgga
    14761 tgggggtggg gaaccctctt ttgacgagct gtggagctgt cggcaaatgg gtaaagctac
    14821 aggagccagt cggatggtac cgttggcacc tgccgacaac aggactgcga tgacgtcctg
    14881 tatgtatacg cttggcagcg agcatcaatt tctgtacttg agtgcgcatg gtgcgcgtca
    14941 cggctggttc aggctgcgct ggctggttga catcgacagg cttgcggcat gtgctgtcga
    15001 ttgggaggcg ctactgccga tgatgcgccg ctacgggggc ctgcctgctg gcgggcaggc
    15061 ctgggcgctc gccgctgcgc tgttgggtac gccgatacca gagccgatgc gtccggtatc
    15121 ggctacccgg caggcgcaca ggctcgcgct gagcgcgctg gccttcatgc aggccagcgt
    15181 tcccgcacca tacccgattg cccacgggtc gggtacaggt aggcttgctc catcagagct
    15241 gctgcgcagc agagctttgg cggagcaagc ggaggccgcc cctctggatg gcggtccttc
    15301 attgtgtagt acctgtggcg aagcagccat gcttgccacc attggcgtta ctagcatcac
    15361 agaaggtgac agtaacgacg actatagccc gatgagcacc gctaccagtt gtgcccccat
    15421 tactccagct gccgcctcca gccaagtcat gaccagaaac acggcggctg cccatcagcc
    15481 ggtcagccgc acttacttgc tttccttaaa agagccaaga cacagactaa gttacctcat
    15541 cagccgtttg tttccttcta cgggggattc ggccgttttt ccactgcctc gccagctgca
    15601 ttttttgtat atccctttac gtccatttct ttggctgaag cggcgatttt caaagcactg
    15661 actcgataag gagtgtgcat tatggttcac ctgcgattat atatgacaaa gctgtatagc
    15721 gtgaacggcg gtgcgttatt tctcaatatt ggatgtatga tcattgttag cctgctggag
    15781 ggttttggca tttatatgct tgttcctatg ctggcggcca tcggcgtatt tgtcggtcat
    15841 tcagggatgc catttctgtc tgatggattg gatcattttt tggcgttcat tcctaaaagc
    15901 tggctgttgc cggggatgtt gatggttttt gtagtgctgc ttacagggca ggctttgctt
    15961 cagcgttacc aatccatcct gaattcgcgg attcagcagc gttttatgcg ttctctgcga
    16021 gtagacgtgt acacttcctt tatgaaggcg cagtgggctt tttatttgcg tcagcgtaaa
    16081 tctgatttta gccatgtgat gacgactgag ctggcgcgtg tcagtcaggg aacgaatttg
    16141 cttcttcaac tgactacagc cgtcatgttt acgctgatcc agattgcgct ggctttttgg
    16201 ttatccccct ctttaaccgg actggtattt ctgagtggat tggggctgtt tgtcgtgttc
    16261 cgccgctcca ttcgaaatgc caaacaatta ggggatcgta cgactgagct atcgcaggtt
    16321 tattttgctg gaattacgga tcacatgaac ggcatgaaag atattaaaag caatctgttg
    16381 gaagcggcga atatccattg gtttcgctcc ctgacacaac gaatggagga taatacgacc
    16441 caatttgtcc ggcaaaatgc gaccacacag ttttttcatc gtacagcggc agctgttttt
    16501 gtcgcttgtg tcatatttat atcgttgcag tggttgcatg ttacatctga aaaactgatt
    16561 gtgctgattc ttatattttc ccgcttatgg ccccgatttg cccttattca agcgagtctg
    16621 gaatacatca tgtctatgat ctccgctttt gaaagtgtca ccaaggtgca acaggagtgc
    16681 gaagctttct ccgatccatc ggtattcaaa ctatcatctg catctgtacg gcaacccctg
    16741 tcccttcgtc atggaattga atgcagccat ctgggttatc gctacgatgg tgcagcagag
    16801 cctgcgctgc atcgtatcaa tttgttcata cccgcgcggg gaatgacagc catagtaggg
    16861 aaatcgggag caggtaaaag tacaatggtc gatgtcctga tgggtttttt acgtccaact
    16921 ggggggcgga ttacaataga cgggcttgtt ctggacgacg aattgttgcc ccagtggcgg
    16981 cagtcgtttg gctacgtgtc acaagaccca tttttatttc atgcgactgt ccgcgaaaat
    17041 ttgatgctgg cagataagga tgctagtgag cagcaactat gggaggcgtt acattttgca
    17101 gccgcagaca gctttgtatc cagactgccc gaagggctgg acacggtcat tggagatcgc
    17161 gggattcgtc tgtctggagg agaacgtcaa cggctagtat tagcacgggc tgtcttgcat
    17221 catcctccgg tacttatact agatgaagcg acaagtgcgc tggatggtga gcatgaagct
    17281 gcaattcagg cagcactgga acggatgaaa ggtcaaatga cgttgatcgt catcgctcac
    17341 cgcctgtcaa ccatcagaca tgcagatcaa attgtcgtac tggatcaagg cgaggtcata
    17401 cagcagggga actaccgcca actggaacaa gaggagcggg gggcgttcag tcagctacta
    17461 tcgtatcaaa gcagtctcac cgccacccct tagccagact tttctgtaac tcagcttaag
    17521 tttctttacg tttggcagtg cttcttttct ttttgactgg agtcggagag atgttctcgc
    17581 ctgcaacagc ctgctgtgct gttggggctg ctggtttacg cgcaggacgt tttttcgcag
    17641 cagggccggg atcggtaacg acaggttgca ctgcctcgat gctggcctga agggcggcca
    17701 ttaaatctac tacgttggtc tgaggttgtg ttggggcgat tcgcacctct tcaccagcca
    17761 ctttatgctg aatgagatcc agcagacgct cgcggtactg atccgtatac tttgctgcat
    17821 caaaaggtgt agatagctgc tcgatcagca tttttgccat ggtcagctcc ttctctttaa
    17881 cctcctcctg ccccggtaag ttaggaactt gagcaatggg gcgaatttca tcggggtaaa
    17941 acatcgtctc caccgccaaa cattcatcca acacccgaat agccgccaga ctgcttttag
    18001 agcggatgga gatttgggca atccctattt tcccggtatc cttcatcgca ttcatgagca
    18061 gcttatacgc attggagcca gcttgatccg gggataaata atacgttttc tgaaagtaaa
    18121 tcggatcaat ttcctgcaaa tccacaaaat ccaaaatgac aatattttta tccgcttgtc
    18181 cgctaacttg ctccagttcc tccttgtcga acatgacaaa ttttcctttt tcatattcgt
    18241 agccttttcc aatttcctcc cattcaacct ccttatcaca aacaggacac tttcgtacat
    18301 agctaagtgg gcttccacac tccttatgaa tataacgcat ggaaatgtcc ttatcctccg
    18361 tcgctgaaaa cattttaacg ggcacatgaa ccagcccgaa gctgattgcg cctttccaga
    18421 ccgtatgcat aacgccagtc ccccttttct taaatcctca ttttgtatcc ttcgattcca
    18481 acgctcggct gtgagcatat ccatttttca cttagtatgc ttcgtacaag tgattgtatg
    18541 aggtgcaaat gaaggctgag aattacttct gcttgcgcat ggttacaaca attttggtgc
    18601 atagtaaggc atatccgatt caaaaggagg tacacaattt atgtccggaa aatcctttcc
    18661 tcggcaaatc aggcatcgtg taggtcaaaa ccatgtcgcc tttcggggac ccgccggagg
    18721 agaacaggat gcattgccgc cagagtttgc cctttcccat ggaatccaac cgccttttcc
    18781 catagctgtg gctcatgtgg atttggaggc tgtagtttca acttcgcctt ctcatagcat
    18841 cccttcatta gatgttgaac ggattataga tgaagactag gtgaactata tttctgaatg
    18901 aatgcagaca acaacaatca ggaggggaag aatagcatga acgtggaacg agcaaaagct
    18961 atttatgatt cgcccgatac cattgccgta caattggatg gtaaaccgat ctggattgag
    19021 catgtagacg aagcgaacgg tatggccact gtacagatag gtagcagacc caccaatacc
    19081 caaaccgtcc gtgtggatcg tctggaagaa caatagaaga ggagcaccaa aacagatttt
    19141 tttccatagt atggggtata gctgtagaaa gatcttggac agctgtagtc tttcatcgca
    19201 gaatgctgct tgaaaggtcc cactccaaca aaaaaaggct cgcaattgct caatgagcaa
    19261 ttagcgaacc ttatttgtaa taataaatgc agtcgagaga gcatgttaaa cgccagacaa
    19321 gttaatttga aggtgcagct ggttcctttc tatgatgacc tttatactgc tatggctctc
    19381 aaatgtggtg aaaccatcag tttagcctct gttgctaatt gaacatcttc caccgacaaa
    19441 cccggagcaa tttcttttag catcagccct tgacccggaa taacatcgat gacagccttt
    19501 tcggttacta tggtctttac aacatttaca gcggtcaggg gcagtttaca ttgttccagt
    19561 attttcggag ctccattttt gttcacatgc tccatggcta caatcactct cttggctccg
    19621 accaccaaat ccatggctcc ccccatgcct ggcacctttt tccctgggat catccagctt
    19681 gcaaggttgc ctttctcatc gacctccagg gcgcccagca cggtgatatc cacatgccct
    19741 ccgcggatga tggaaaatga aagtgcactg tcaaaaaagc atgctccttc catagttgta
    19801 acgtagtttc cgcctgaatc gatacaatcg agcctttctt ttccctgagc cgctttgggg
    19861 cctacaccga ggattccgtt ctccgcctgc agcataatat gaatgtcctc ggggatatag
    19921 tccactacca ttgtaggcaa tccgacacca aggttgacaa cttcaccatt tttgaattcc
    19981 tgggctattc ttcgagcaat aaattctctg ttattcatgc gttttcaccc acctttacaa
    20041 ttgcgtcgac aaatattccg ggaacgttga catgattggg gtcaatttca cccgtcttta
    20101 cgtattcgtc tacctgagca actacatact ctgccgctgt agccataacc atattgaagt
    20161 tacgtgaaga accgttgatg acaagattcc ccgcttcatc agccttatgg gctctaatta
    20221 atgccacatc ggctttgagc ggcagttcga gcaagtattc cttttcatca attttgattt
    20281 tctgttttcc ttcctctaca acggtgccta cacctacagg tgttaaaacc ccgcccaaac
    20341 cggctcctcc tgcgcgtatt ttttcagcga gcgtgccttg cgggaagagt tggacctcag
    20401 cttctttcgt catcaggagc cttcccgttt ctggattgga gccgatatag gatgcaaaaa
    20461 tccgctttac tctaccgctt tttacaagtt tatagataga taattccggt gtgcctgtgt
    20521 cattggaaac aatcgtaaga ttgctggcag gattggtgtc gacaagcgca cgaaccaggt
    20581 cctctggaaa gcctcctgcc agaaaacctc cgaccatcac cgtgtctccg tctttgacct
    20641 tcttaactgc ttcttcagcg gagattactt tgttattcat ggttccttct ccttatatat
    20701 atatttttag gaaagcaaac tttattggag atagtcgtag aggacgcttc catatggaag
    20761 cgttaaatca gcaataaaat gtttcccgcc aatataagct ttaaccggca aatctgccac
    20821 tggagcgttg acatggggga tcaagcttaa tctggcaggc cctgaccagg cgccttttac
    20881 agtaatgttc tcgagattat acgctactaa ttgagcgatt ttgggggtac cgtcaacatc
    20941 aggaattagc tttaaattaa cttgcgtttt tgcgatggct tttgccgttt ccttttcatc
    21001 aagaatgtta tatttgaaag gcatagttcc cgtggccacc aggacgtgat tataatgcaa
    21061 tgtacccgtc agcgtctccg tttcctccac gctcaggcga ggctttgccc attttttcgg
    21121 aaatccccag acttcgcgtc cccccagaat agcaggcgcg ttatccaaat acatttgggc
    21181 gacaaaattg cagggttctc cttgaaaagt acatggaatg acaataccgc tttcctcata
    21241 gcatcctaaa ccggatgaat cgggcatctt gatccattca taggagaccg tattgcttcc
    21301 atccggctca agaggctctg ggaccgcctg tctaatcgca gcaggatcgg tctcataggt
    21361 aatgataaaa aattcccggt tgatgaagcg gtatggtggg cgcccgtagc tgccgctagc
    21421 cgcaggcata gattggagtg aaagtacatc tttttgattc atagcgatct cccttccttt
    21481 taagagatag ttctaaaagt catcctgaac acgcacttta aatgagcgca ttttcaacta
    21541 gcatggctat tcccattcct gttccgatgc ataacgaggc gatgccgtag cgtgaagatc
    21601 ttcgcaccat ttcgtgaacc aacgtagtca atatcctagc accgctggca ccgacaggat
    21661 gcccgatcgc gattgcgccg ccattgacat tcaccttctc cggactgacc cctagctctt
    21721 tcactaccgc taatgcttgt gaggcaaacg cttcattaat ttcaaaaaga tcaatggcat
    21781 cgatggatat accttgctgc ttaagaagtg tcgaaatggc tttcactggc cccattccca
    21841 tatatgcagg gtcaacgcca acaagtgaat atcccttgat atatgccaat ggctttaatg
    21901 catgttcctt gcatttgtct tccgacacta caagcacggc cgccgcgcca tcattgattc
    21961 ctgaagcatt tccagcggta accgtcccgt tctccttaaa tgcaggtttt aattgagaaa
    22021 gtttttcttg cgttgtattt cctcttatgt gttcgtcctc tgtgaaagaa atagtttctt
    22081 ttttggtttt gatcatgacc ggaacaattt gctcttcaaa aagcttcttg ttttttgctt
    22141 ctacggcttt tagctggctt tgataggcaa attcgtcctg ttcaagtctt gaaattccat
    22201 atttctcggc aacattttct gcggtaattc ccatatggta atggttgatc gggcacgtaa
    22261 ggccgtcggc cactagggag tctaccaact caccgttgcc aagtttgtag ccgtttcttg
    22321 cattccttag caggtaaggg gcattcgaca tgctctccat gcctccggcc aagacgatgt
    22381 tgccttgttc agccaatatt gaattgtaag ctaaagcaac ggcatgaagt cctgaaccgc
    22441 aaaccgtgtt tatcgttgtt tcgggtacat caatagggat accggctttt aatgccgcct
    22501 gtctggcagg attttgtcca ttgcccgcct gaagaacatt tcccaaataa atctgatcaa
    22561 tcaaagaagg ctctaattta ctttgctgaa ggcatgctgt catcacagtt gcccccagtt
    22621 cggaagcgct tagaggcgca agggttttgt taaaagagcc gaccgctgtt ctcaacgggc
    22681 ttactaaagc tacttttttc attaaaaact cacattcctt tcgctgtgtt caaaacacaa
    22741 tacatccatg attgcacttc aattcgtaat ttccgctctt aacctacgag aagcagcgac
    22801 tgcaagatac atttgcatgc gggcatatca tggtgcctaa gacagtgagt gtgacggttc
    22861 gatcgccttc tctcattgga aattaaaacc attttcatca tagttctaat gcagattttg
    22921 ctcaatgtcc aaatatttac acatatctat gtacagatgt ttatagggcc atatactcca
    22981 caataattag gccattctaa cgttttctgt taatttctta atttttctga aaatcatgat
    23041 cattaattga attttatgtt aaaaatgaaa gttgcaatcc atacgtgaga aagttttcct
    23101 cgcaatatca tctaactcat cgctgggtaa taaaaaaagc ctccagaatt ttctgaagac
    23161 ggctttgcct ttcaatattc atgatcttcg ttatattgtg ctagctcgct tcttgttaac
    23221 agtgtcaccc gaaagtgcgc ttttttcgca tgaacaaaaa aagaagccga cttgcttgaa
    23281 agcaatcggc ttggaacatt aaacttcaac aactcacgaa aaatgtacat cttctgtcgc
    23341 aagtaaacgc acaaaacgat tgccaagcat accattatga tgagctacga tttgttcacc
    23401 gcttagcacc ttgctatcaa atgtactatg cgcatccaat acgagtacgt tgttctggta
    23461 tcccagacta taggcgcttc ggcaagtcgt gtcgaggcaa aactcggtct gcatccccgc
    23521 gattacgagt tgatcggccc ccagttcctt cagtacatgg cccaattcgg tttggtagaa
    23581 gctgtcccag gatgatttac ggacaattcg ttcatgagga agaggacgca ctacgtcggc
    23641 gatggcccag cctacactgt tttctcggaa atcctcatcc gcttcatcgg tatgctgtac
    23701 aaaaatcacc ggtgtacctg tagctctggc tttgtccaaa agctgctgca aatgcgctac
    23761 aacttcctgc tcacgataca gcttctcatc atacatgaac atagcctgct gaacatcaat
    23821 catgagtaaa acggtttgcc ccatcgtttc aatccctccc tgtgtgtatc actaacttac
    23881 aatagcatgt cttcatgcct tgcggcgaca taaggtgaac tatataataa agaacaagtt
    23941 ggaacggtcc gattcggacg aaaggtgatt aaaatatatg acaatttcgc aggagcagtt
    24001 tacgttccgt tctgtctcag aggcacagac cgggtcattg gctggttttt tggcagccaa
    24061 agcggttccc ggaacggtga ttgtgctgga tggagatctg ggagcgggca aaactgctt
//
