LOCUS       NZ_JANAVN010000010     20237 bp    DNA     linear   CON 26-JUL-2024
DEFINITION  Paenibacillus sp. Lou8.1 NODE_10_length_264709_cov_153.309834, whole
            genome shotgun sequence.
ACCESSION   NZ_JANAVN010000010
VERSION     NZ_JANAVN010000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. Lou8.1
  ORGANISM  Paenibacillus sp. Lou8.1
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 264709)
  AUTHORS   Gonzalez-Pimentel,J.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAY-2022) Agroquimica, Microbiologia Ambiental y
            Conservacion de Suelos, Instituto de Recursos Naturales y
            Agrobiologia, Av. Reina Mercedes 10, Sevilla 41012, Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024213565.1-RS_2024_07_26
            Annotation Date                   :: 07/26/2024 02:53:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,316
            CDSs (total)                      :: 5,255
            Genes (coding)                    :: 5,159
            CDSs (with protein)               :: 5,159
            Genes (RNA)                       :: 61
            rRNAs                             :: 3, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 40 of 96
            Pseudo Genes (incomplete)         :: 74 of 96
            Pseudo Genes (internal stop)      :: 9 of 96
            Pseudo Genes (multiple problems)  :: 25 of 96
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:00:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 101780
            Orig. end                         :: 122017
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JANAVN010000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20237
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="proteusin"
                     /region_number="1"
                     /rules="(PoyD or TIGR03793)"
                     /tool="antismash"
     cand_cluster    1..20237
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PoyD or TIGR03793)"
                     /kind="single"
                     /product="proteusin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20237
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10237](-)"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10237)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
     gene            134..994
                     /locus_tag="NLX78_RS15660"
                     /old_locus_tag="NLX78_15650"
     CDS             134..994
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369717.1"
                     /locus_tag="NLX78_RS15660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15650"
                     /product="TrmB family transcriptional regulator"
                     /protein_id="WP_165176560.1"
                     /transl_table=11
                     /translation="MKPKPNILEILRDLNFSEYEAKAYVTLLESSPLSGYAVSLNSGVP
                     RSKIYEVLSGMVNRGDIMVSQENTPLYVPLPPHELIAQRKRKAEQIFNVAQESLEQYTA
                     SFQNRENIWNISGYEAIINRINEGVKGAKHRILLEIWKEDAEVFRDALEQVAQQGIEVI
                     IVAYGELNFDFATVYRHDMSEEITSEIGGRWIVLSIDDREVVAGILSLGDDSRAAWTLH
                     PGLVMPITEVIIHDIYIMEILYEFREQLEEKFGPNLIHLRNKFAMGPNGKGYYIPLTEK
                     SIKRV"
     gene            complement(1080..2702)
                     /locus_tag="NLX78_RS15665"
                     /old_locus_tag="NLX78_15655"
     CDS             complement(1080..2702)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429103.1"
                     /locus_tag="NLX78_RS15665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15655"
                     /product="DUF1593 domain-containing protein"
                     /protein_id="WP_254350915.1"
                     /transl_table=11
                     /translation="MRERKGLSIFLLAMICILIISGCSGKAPAVVKDESAAPTEKQTEN
                     KVENKTTKARTVITTDGEVDDMNSVIRFLLYSNEMDLSGIVLTSSVYHYAGDEKAGIKP
                     FRWTGTQWVTDMIDAYGEIYPNLIKHAEGYPKPEYIKSVTKIGNISNKGEMDKETEGSN
                     FLKTLFLDDDKRDLYVQTWGGTNTTARALKSIEDEYKNTDQWETIRKKVSDKLVLYIIL
                     DQDDSYNNYIAKNWPDIRIINDQSNFWHFAYAWKMHTEEVNSKLHGEWNFKNIKEGHGK
                     LLNMYALMGDGNIIKGELDEEQRGSEAYLKKNPQYDKYDFISEGDSPSFFYLIDNGLRS
                     MENPTYGGWGGRFGVVNDKLFRNTVLDYDVHTKKFEAEYSLMRWFDDIQNDFAARADWA
                     IASDYKDANHNPTLTIKEGIDLTASPGEKITLHAEGADPDGDQLTYKWWRYFEADTYED
                     SKVKPAQVKPELLGEMQLGLHREVAKGEKVNTIDLQGSDTNTASFTVPADAKSGNTLHI
                     IAEVQDNGKHPLKHYQRVIITVK"
     gene            complement(2939..4021)
                     /locus_tag="NLX78_RS15670"
                     /old_locus_tag="NLX78_15660"
     CDS             complement(2939..4021)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0046417 - chorismate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369718.1"
                     /locus_tag="NLX78_RS15670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15660"
                     /product="bifunctional 3-deoxy-7-phosphoheptulonate
                     synthase/chorismate mutase"
                     /protein_id="WP_013309063.1"
                     /transl_table=11
                     /translation="MSTNENSLELLREQLDATNLQLLELLSQRAELAGQLGKLKEAQGV
                     PDFDPVREQQMLDKLIAANRGPFDDATIRQLFKNIFKASLNYQKEEHKKHLIVSRKNQP
                     DSTVIKVKDTLVGGKASIMVAGPCSVESYQQTREVGAALKEAGVPILRGGAFKPRTSPY
                     DFQGLGVEGLQILKRVGDEFGLATISEIVDPRHLEEAIQYIDIIQIGARNMHNFELLKA
                     AGETRTPVLLKRGLAATMEEFLHAAEYIVSRGNTQVMLIERGIRTYEKWTRNTLDISAV
                     PILKKESHLPVLVDVTHSTGRKDILAPCAKAALAAGADGIMVEVHPNPAVALSDAQQQL
                     NIPEFHNFLSEVKESGLFKA"
     misc_feature    4004..4019
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 22.59"
                     /tool="antismash"
     misc_binding    complement(4110..4381)
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     gene            4544..5404
                     /locus_tag="NLX78_RS15675"
                     /old_locus_tag="NLX78_15665"
     CDS             4544..5404
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280150.1"
                     /locus_tag="NLX78_RS15675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15665"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_061831216.1"
                     /transl_table=11
                     /translation="MSKIRVSAVQYHLHTIDSFEQFALQSEHYIKTAEEFGAEFVLFPE
                     FFTTQLMSIGDSEGKALTINDLPDFTDRYLELFTSFARRTGMHIIGGTHVVRRNERLYN
                     TAHLFYPDGRVATQDKIHITPTEVHEWNMAPGEGLNVFETSKGTIAMLTCYDIEFPEIV
                     RMAKTKGADIIFCPSCTDDRHGFYRVRYTSHARAVENQVYVVLTGTVGALSTVDFMRAN
                     YGQAAVITPNDIPFPPRGIMVEGELNNDMIVTADLDLQLLYDVRERGSVTTWRDRRTDL
                     YTDWS"
     gene            5421..6092
                     /locus_tag="NLX78_RS15680"
                     /old_locus_tag="NLX78_15670"
     CDS             5421..6092
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280151.1"
                     /locus_tag="NLX78_RS15680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15670"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_061831215.1"
                     /transl_table=11
                     /translation="MYRKEWFIFDGDRPLRAVIRNYSTADYEGLLRIQQESFPPPYPQE
                     LLWSREQIASQTEHFADGALCVEIEGELAGSVTSLLMHYNPEHPQHTWDEVADDGYIRT
                     HCEDGKALYVIDLAVRPAYRRLGLGKWLIFSLYHLVIERRLDRLLGAGRMPGYQHHADQ
                     LSAEAYVDAVVSGELKDPVLTFLLRCGRVPVCILPNYLDDEQSRNYAALMEWRNPFHTH
                     H"
     gene            6117..6788
                     /locus_tag="NLX78_RS15685"
                     /old_locus_tag="NLX78_15675"
     CDS             6117..6788
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009595536.1"
                     /locus_tag="NLX78_RS15685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15675"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_254350916.1"
                     /transl_table=11
                     /translation="MEYHRITHIEDPLFASMHQLMQRVFPPEEVLEYSLWKEPLEDPGI
                     RVFVAVQDDKVVGATEYRYYEDFNVAMTDFTIIGQSGLGIGRFLWTRRQNDLHALAQAS
                     GQQLLGMFAEIYDPYRGNEHPFGGVKPMDPYVRREVLSHLGYKRLDLYYVHPSWNNDGV
                     AVEGLNLGFMPEDDSMEEVSAKLVAAFLRRYYTVLPNKPAVWNEMIDGLEAKSTVALLP
                     L"
     gene            complement(6878..7057)
                     /locus_tag="NLX78_RS15690"
                     /old_locus_tag="NLX78_15680"
     CDS             complement(6878..7057)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821368.1"
                     /locus_tag="NLX78_RS15690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15680"
                     /product="hypothetical protein"
                     /protein_id="WP_235307519.1"
                     /transl_table=11
                     /translation="MYKDPMSQADMEYKRYKALNPVEEDDRRSADKTITDDISAEDNPR
                     GVASAKPEPRDQGK"
     misc_feature    complement(7114..7125)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.53"
                     /tool="antismash"
     gene            complement(7149..7409)
                     /locus_tag="NLX78_RS15695"
                     /old_locus_tag="NLX78_15685"
     CDS             complement(7149..7409)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369720.1"
                     /locus_tag="NLX78_RS15695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15685"
                     /product="hypothetical protein"
                     /protein_id="WP_061831212.1"
                     /transl_table=11
                     /translation="MANRDDRVNELHDNDFEPSLQNAETNWENLTEGPDTPLEDVPDAD
                     ELTPNSPVDPSAPAEFLHGTDLLNGTDGDEEEQLDSDDMLD"
     misc_feature    7360..7374
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.27"
                     /tool="antismash"
     gene            7593..7880
                     /locus_tag="NLX78_RS15700"
                     /old_locus_tag="NLX78_15690"
     CDS             7593..7880
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369721.1"
                     /locus_tag="NLX78_RS15700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15690"
                     /product="hypothetical protein"
                     /protein_id="WP_023987328.1"
                     /transl_table=11
                     /translation="MEWYMFGPMISRIRVGQKASTPGFSRTLIRRPEGLYWTDGGQAGK
                     IVEIRDYLFSDIWTIYEDEDCEPWLGLREQKERREQEMIINQYEDFTKNE"
     gene            8013..9902
                     /locus_tag="NLX78_RS15705"
                     /old_locus_tag="NLX78_15695"
     CDS             8013..9902
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686330.1"
                     /locus_tag="NLX78_RS15705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15695"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_254350917.1"
                     /transl_table=11
                     /translation="MRHVPKAVATLLAVIVLLLSLGYSAYAAKMTPERDYKIPSWDMRW
                     GAVNEDGSLDEVKDSSKAWMHIENDTQLLRQPGNIGSAWIRMKLPSLNDETPAVLFENI
                     YGRHITLYKDGTNFYESYRGYNYENNRILIPLKPEDSGKTLYIWTESSKNRLGIIGNVM
                     TGDYRDLLGTLVRMDVLDIVLGSTFIFIALVLLICSFFLFRPSMAMWLSLSAIVLSIGL
                     MIVTYSPFLYTFYRGYGKLYLQLFDVALFILLPSLAFFFEQNINSIILIRKFRKLLTAY
                     SLFCFTMMIVNLGAQERLNDIYYFFSVVILGILLVALLILLVFASVRMALKGDHEAIIL
                     STGFAFFAVISIGELSWFFILDGHYNMFLWKWGVFGFVLALIAILGRRLAEKHKQVVRY
                     SRELEMFNNELQRSEKMEIISDLAASVAHEVRNPLQVTRGFLQLMSKQEDGKNKDYLHI
                     ALEELDRASAIITDFLTFAKPEFDQTKTLTILNEFKHIEGIISPMANLQGGKISLDIPQ
                     EIKVRGNSSKFKQAFINIIKNSIEALRDQGHIHIWAYVDNGEAVIHIRDNGEGMDAQTL
                     SRLGEPYFSNKTKGTGLGMMVTFRIIETMNGKITFTSAKGVGTEATIRFPVAG"
     gene            complement(10001..10237)
                     /locus_tag="NLX78_RS15710"
                     /old_locus_tag="NLX78_15700"
     CDS             complement(10001..10237)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: TIGR03793"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429107.1"
                     /locus_tag="NLX78_RS15710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15700"
                     /product="NHLP leader peptide family RiPP precursor"
                     /protein_id="WP_013309068.1"
                     /sec_met_domain="TIGR03793 (E-value: 4e-20, bitscore: 65.3,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATEVLQTQVIQKAWEDASFREKLMTDPKSAIRDVLGVVIPDHIQ
                     IKTLEETPDQFFLVIPPDPSGVLAASQKPRSMW"
     gene            complement(10313..11248)
                     /locus_tag="NLX78_RS15715"
                     /old_locus_tag="NLX78_15705"
     CDS             complement(10313..11248)
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429108.1"
                     /locus_tag="NLX78_RS15715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15705"
                     /product="class 1 isoprenoid biosynthesis enzyme"
                     /protein_id="WP_367988318.1"
                     /transl_table=11
                     /translation="MEWYFAYKDELEKVFRQAEERTSTFPAPFQQEGLNFLARFNPLRE
                     DSTRNYICYLLPFWLQELTGLPPETCHKLSLGNVFIMAHYLIQDDVMDTAADNRKMQLA
                     LSQLFYTECISVYRDLFPATSPFWSYARTYVDEWAVSVISEGTEDYFQGERNKVALKAS
                     PLKMAGTGALLLAGRADLIQTITNITDLALLVLQMSDDWADWSEDLVEHSYNCLLSHIS
                     AEQKTAYCEGLGPQQIQEAIYVRGVLASYVSIADQAVQQLETLEPSIHGLSSFAHSIAA
                     ELGEVAAEIEGGRSHLRRGGLDYWLSKNMK"
     misc_feature    11320..11332
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.58"
                     /tool="antismash"
     misc_feature    complement(11343..11357)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.42"
                     /tool="antismash"
     gene            11441..11917
                     /locus_tag="NLX78_RS15720"
                     /old_locus_tag="NLX78_15710"
     CDS             11441..11917
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821363.1"
                     /locus_tag="NLX78_RS15720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15710"
                     /product="hypothetical protein"
                     /protein_id="WP_254350919.1"
                     /transl_table=11
                     /translation="MKKQLKLAAAILYGGVMMYGTAGAAGASGTEPGNSLQTLTPNGSI
                     QGAARQWNVEPQDDHGHGHVHRHRHGKRPGGLNHHLNEKVAKLLGITPVQLEKELGQGK
                     SLAEVAKSKGIQEDQLIDKLKNEMTVDLKRLVNRKGPITFDRKSGASNEAQLKR"
     misc_feature    complement(11460..11474)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 17.31"
                     /tool="antismash"
     gene            complement(12008..12589)
                     /locus_tag="NLX78_RS15725"
                     /old_locus_tag="NLX78_15715"
     CDS             complement(12008..12589)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012818485.1"
                     /locus_tag="NLX78_RS15725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15715"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_254350920.1"
                     /transl_table=11
                     /translation="MVDQFLTKEAILDATEDVLRRFGPEKTSVVDVARSLNVTHATIYR
                     HFPSKTALRLAVVKRWFHVITEPLDKTFQQECSASERLLIWMDTLIRIKHTKAQQDPEL
                     FAIYTKIAEESDDIANEFVNHIIGNITKIVEAGISNHEFKEGLAEEVARGIYVATVRFH
                     HPLHSREWLLPTIHQEFEVVWNLIMSGILQ"
     gene            complement(12589..13551)
                     /locus_tag="NLX78_RS15730"
                     /old_locus_tag="NLX78_15720"
     CDS             complement(12589..13551)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020614817.1"
                     /locus_tag="NLX78_RS15730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15720"
                     /product="aldo/keto reductase"
                     /protein_id="WP_254350921.1"
                     /transl_table=11
                     /translation="MKQRRLGIDGPLVSSMGLGCMGMSGGTYGSADRAESINTIHAALD
                     AGVTLLDTGDFYSSGHNELLVAEALKGRKREDAILSVKFGMLISPDGSYSGIDCRPQAV
                     TNSLSYTLARLNTDYVDIYRPARLDPTVPIEETIGAIADMVKAGYVRHIGLSEVDAEIL
                     RRAHAVHPITDLQFEYSLMSRDIEKEILPTARELGISITAYGILSHGLLSGTWDKDRRT
                     DGFDFRKHLPRFTGENLDKNLELVEALRTIAEEKNTTIASLATSWVLSRGDDIIPLIGA
                     RRLTQLQDAVTALDLQLTASDLEKIQEAVPADAAAGTRY"
     misc_feature    13902..13919
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 24.87"
                     /tool="antismash"
     gene            complement(14037..14267)
                     /locus_tag="NLX78_RS15735"
                     /old_locus_tag="NLX78_15725"
     CDS             complement(14037..14267)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NLX78_RS15735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NLX78_15725"
                     /product="hypothetical protein"
                     /protein_id="WP_254350922.1"
                     /transl_table=11
                     /translation="MIATICSATELLEIAGVSYKNPVNHPTGLEIHKNIITAKPNKYVD
                     FAIEIGKVVDIYTDDEDLKETIDFFKLFKDS"
     misc_feature    14247..14260
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 20.0"
                     /tool="antismash"
     gene            complement(14300..14476)
                     /locus_tag="NLX78_RS15740"
                     /old_locus_tag="NLX78_15730"
     CDS             complement(14300..14476)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014068.4"
                     /locus_tag="NLX78_RS15740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15730"
                     /product="DJ-1/PfpI family protein"
                     /protein_id="WP_254350923.1"
                     /transl_table=11
                     /translation="MKTKGDIVTIGVTKDPVISYEDFKVTPSVALDEVSAEDIQLLIIP
                     GGDNTPLKTNKNF"
     gene            complement(14635..15102)
                     /locus_tag="NLX78_RS15745"
                     /old_locus_tag="NLX78_15735"
     CDS             complement(14635..15102)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369729.1"
                     /locus_tag="NLX78_RS15745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15735"
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="WP_254350924.1"
                     /transl_table=11
                     /translation="MEGEDHLKNTGMTRPLDTLGRIVIPKEMRTSMGIQAGESLEFYLD
                     VETGLLSMRKYIGVCCHLCYSIQDLSYFRDSFLCKKCINDLKGNIGVSPLPFPVIKKPA
                     YKEKSNHRSSSQHLVENLRKLMREHPTAKQGEYAEWLGVSQGRISQLKKLL"
     misc_feature    complement(15249..15263)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.62"
                     /tool="antismash"
     gene            15283..16665
                     /locus_tag="NLX78_RS15750"
                     /old_locus_tag="NLX78_15740"
     CDS             15283..16665
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821361.1"
                     /locus_tag="NLX78_RS15750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15740"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_254350925.1"
                     /transl_table=11
                     /translation="MEITPTIQAEIQTYLKRKGLTMTKFGHTIDLNVGTVSSIVTGNRS
                     ISVHQLDSITAGMNLPPDYFYERYIEECIEESPLNWKKISPFLYRCIELGRLDCLQRVV
                     ILLLDNPNYPPSLFEVAENVYKDGYNEAAAYLYKKVAESEKQQHSERLAICQYRLFQIN
                     IGQDRAINLQAAIEFAPFVDRLDEIEQLDALKDLANVYRSLSMWDKVYEFAHQMGQMGK
                     IQYNLIHNSKRKGLEPRKKLSRPLFVYIVYSELLCANACDAKGDHEQALEHIRGYADLS
                     WVKEKDPDSLYWKKQYQQWAKINTYVNRLMSGDISVLPDYVEHMAAENEIFAELINVIE
                     VANRYNVDVDHILKRFESQIAAYQVPLSSDMYTQQVLPEEYVRFWYKLAKYNLNKGRYS
                     YGFKCLIDAFEKAVTLKHALLIANCVGLFERFRAYAEPEILARYNMWERNDRKDGFAIC
                     SD"
     misc_feature    complement(16860..16874)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.01"
                     /tool="antismash"
     gene            16891..17076
                     /locus_tag="NLX78_RS15755"
                     /old_locus_tag="NLX78_15745"
     CDS             16891..17076
                     /GO_process="GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280170.1"
                     /locus_tag="NLX78_RS15755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15745"
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="WP_254350926.1"
                     /transl_table=11
                     /translation="MNRYETVTLIQQVENARQHLHDLYEEYGFGHACVLEQSMLLDELI
                     NQYNRMFQTKKLPHYV"
     gene            complement(17305..18531)
                     /locus_tag="NLX78_RS15760"
                     /old_locus_tag="NLX78_15750"
     CDS             complement(17305..18531)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309078.1"
                     /locus_tag="NLX78_RS15760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15750"
                     /product="acyltransferase"
                     /protein_id="WP_254350927.1"
                     /transl_table=11
                     /translation="MSKPRIAEWTELRGLAYLAVVLQHCIGEYIYRSDIQQPDSVMLAM
                     LYHLTRFGTPTFVFLSAALLFYNGNKPIGYPRYIGRRFRDIYVPFLCWTVIYWVCTQNW
                     STAQWGYIYFYKGMFEEMIIPVSGYHLWFVVMIFQFYILFPLFSKATGKVQAFLRRYST
                     KRRKQLVLAIMLIAATAYALLLQWSYYDMSAWSTGLPSFWQTLLDYRTYNFVMYFFYFM
                     LGAVCAYMTDTWRGLAKQTLPWNVFVFIGLFMLMGHTMLIQSGDTINLNISTYLKPSTF
                     VLIVSQLLLLYGLLLHLQKDTRSEPFRRMLNWIGRYSFGGYLAHALVLAFISYYTRSLA
                     LGDHHFTATLITFIVVASVSLGISWLFAHLPGGNWIVGSKGRQRLNWHSFRFQFLSSKR
                     ASKSTQELG"
     gene            18750..19757
                     /locus_tag="NLX78_RS15765"
                     /old_locus_tag="NLX78_15755"
     CDS             18750..19757
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429118.1"
                     /locus_tag="NLX78_RS15765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_15755"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_254350928.1"
                     /transl_table=11
                     /translation="MKKTLLVYMLLIAAFALYVFRYEQSGPLNGTWEDKGLRGSIGETY
                     IMITFQSGLEYWKSGLKGFEDAGDALGVTVEYRGATRYDAQEQTTVIEQAIARKPAGIA
                     ISAIDPHSLIPVINKALDAGIPVVLFDAEAPGSRAYSFLGTDNYKAGVTAADKMAELLG
                     REGQVAVLTLPGQQNHEERSRGFRDTIQRQYPAMKVVEVADGRADAMVSRDESQRLMKA
                     YPKLAGIFVTDATGGTGVGEAVLSQKNSHPLKIISFDTNKATLDMIRGGTISATIAQGT
                     WNMGYWSLQYLFHLHHRLTIPAPSSSGDNTPLPVRVDTGISVVTRANVDDYYAK"
ORIGIN
        1 ttccctgtga aatataatag ttgctactaa agtgactact ataaaaacgt tactaaaaag
       61 atagtgtgta tatcagtttt tgtcaagggg aagtgatata gtaaggatga acacgaattg
      121 aggagaagac gtcatgaaac caaaaccaaa tatattagaa attctacgag atttgaattt
      181 tagtgaatat gaagccaagg cttatgtgac cttattggaa agctctccac tttcgggata
      241 cgccgtttca ttgaattccg gggtaccgag atccaaaatt tacgaggttt tgtctggaat
      301 ggttaaccgt ggggatatca tggtcagtca agaaaatacg cctctgtatg tgccgcttcc
      361 gccacatgaa ttgattgccc agagaaaacg caaagcagag cagattttca atgtggcgca
      421 agagagtttg gagcagtaca cagcatcatt tcaaaataga gagaatattt ggaatatttc
      481 ggggtatgaa gccattatca atcgcataaa tgaaggggta aagggagcaa aacaccgaat
      541 tttattagaa atttggaaag aggatgccga ggtgttccga gatgccttag agcaagtcgc
      601 tcagcaagga attgaagtga tcattgtagc gtatggggag cttaactttg atttcgctac
      661 tgtttaccgc catgatatga gtgaggagat tacgtctgaa attggtggtc ggtggattgt
      721 acttagcata gacgaccggg aggtcgtagc tggcatactt tcacttggtg atgacagccg
      781 cgctgcatgg acgttgcatc cggggctggt gatgccgatt actgaagtga ttattcatga
      841 tatttatatc atggaaatcc tatatgagtt ccgcgaacaa ttagaggaga aattcggccc
      901 taatctaatt catcttcgca ataaatttgc tatgggcccg aatggcaaag gatattatat
      961 tcctttgact gaaaaaagca ttaaacgtgt atagagattg tccgaggttc gatgtgcaaa
     1021 aataaacagg cccatggagt gttattccat gagcctaatt ttattgatgt tgtgttctat
     1081 tattttacgg ttataatcac acgttgataa tgctttaaag gatgtttacc attgtcctgt
     1141 acctctgcaa tgatatgaag cgtatttcca gacttagcat ctgctggaac tgtgaaactt
     1201 gctgtatttg tgtcacttcc ttgcaagtca attgtgttta ctttctcgcc tttagctact
     1261 tctcggtgaa gcccaagctg catttctccc agcaattcag gtttaacttg tgcgggtttt
     1321 actttggaat cttcatacgt gtcggcttca aaatatctcc accatttgta agtcaattga
     1381 tcaccgtctg gatctgcacc ttctgcatgc agggttattt tctcccctgg actagccgtt
     1441 aggtctattc cttctttaat ggtcaatgtt ggattatggt tggcatcttt gtagtcggat
     1501 gcaatagccc aatctgcacg agcagcaaag tcattttgaa tatcatcaaa ccaacgcatc
     1561 agagaatatt ctgcttcgaa ttttttcgta tgcacatcat aatctaacac agtatttcta
     1621 aacaatttat cgttaacgac accgaaacga cctccccagc caccataggt tgggttttcc
     1681 atactccgca atccgttatc aattaaatag aagaaggatg gagaatcacc ttcagaaata
     1741 aagtcatact tgtcgtattg tggatttttc tttaagtagg cttcactgcc tctttgttct
     1801 tcatccaact cgcctttgat gatattgcca tcgcccatca aggcatacat attgagcaac
     1861 ttgccatgac cctctttaat atttttgaaa ttccattccc cgtgcaactt gctgtttact
     1921 tcttctgtgt gcattttcca agcataagcg aaatgccaga agttagattg atcattaata
     1981 attctgatgt caggccaatt tttagcgatg taattattgt agctatcgtc ctggtccaga
     2041 atgatgtaca gtacgagttt atcacttact ttttttcgaa tcgtttccca ttgatctgta
     2101 tttttatatt cgtcttcaat ggactttaaa gctctggccg tggtattggt tccaccccaa
     2161 gtttgtacgt ataaatctct tttgtcatcg tccaggaaaa gcgttttaag gaaattggag
     2221 ccttccgttt ctttgtccat ttcaccttta tttgaaatgt tacctatttt ggtaacgctc
     2281 ttgatatatt caggctttgg atatccctcg gcatgtttaa ttaagttggg ataaatctct
     2341 ccgtaggcat caatcatgtc cgttacccat tgtgttccgg tccatctaaa tggcttgata
     2401 ccagcttttt catcacctgc ataatgatat acagagctag tcagtacaat cccggacaaa
     2461 tccatttcat tggagtaaag aaggaagcga atgacagagt tcatatcatc tacttctcca
     2521 tcggtagtga tcaccgttct ggccttggta gttttatttt ctactttatt ttccgtttgt
     2581 ttttctgttg gagcagcgct ttcatctttc acaacggcgg gcgccttacc actgcaacca
     2641 ctgatgatca gaatacatat catggctaat agaaaaatgc ttaacccttt tctttctctc
     2701 atttctgttc ccctctctga acgttcctat gatgtttttt gtggattata accatgtagg
     2761 tattcttttt attcaagaat taggcataaa aaaaacctaa acatatatat gtctcaacaa
     2821 aagtcgagca tatatacatt taggttttgc ctgcatgatc agtcacaatc ctgatccaat
     2881 tctacatcat tatctgagaa aatgaaagcg gtttatgaat gccggcataa aattagtttt
     2941 acgctttgaa taaaccggat tctttgactt cagacaggaa gttgtggaac tcaggaatgt
     3001 tcagctgttg ctgagcatcg gacaaagcga ctgccgggtt cgggtgaact tccaccatga
     3061 taccgtcagc tccagcagct agggcagctt tggcgcaagg ggccaggatg tccttacgtc
     3121 ctgtagagtg agtcacgtct accaatacag gcagatggct ttcctttttc aaaatcggaa
     3181 cagcggaaat atccagcgtg ttacgcgtcc atttttcgta cgtacgaata ccgcgttcaa
     3241 tcagcatgac ttgcgtgtta ccacgggaaa cgatgtattc agcagcatga aggaactctt
     3301 ccattgtggc agccagtccg cgcttgagca gaaccggagt tctggtttca cccgcagctt
     3361 tgagcaattc aaagttgtgc atgttgcgcg caccaatttg gataatatcg atgtattgga
     3421 tcgcttcctc caaatgtctt ggatcgacga tttcactgat tgtagccagc ccgaactcgt
     3481 cgcctacacg tttaagaatt tgcaatcctt ctacgcccag tccttggaaa tcatacgggg
     3541 acgtacgtgg tttgaacgca ccaccacgta gaatcggcac accggcttcc ttgagagccg
     3601 cacctacttc gcgagtttgc tggtagcttt ccaccgagca gggacctgcg accataatgg
     3661 aggctttgcc gcccaccaac gtatctttaa ccttgataac tgtgctatcc ggttgatttt
     3721 tgcggctgac gatcagatgc tttttgtgtt cttctttttg atagttcaaa gaagccttga
     3781 aaatattttt gaacagctgg cgaatcgtag catcgtcaaa tggtccacgg ttagccgcga
     3841 tcagcttgtc cagcatttgt tgctcgcgta ccggatcaaa gtcaggtacc ccttgagctt
     3901 ccttcaattt tccaagttgt cccgccagtt cagcgcgttg ggacagcaac tccagcaatt
     3961 gcaaatttgt agcatcgagc tgttcccgca acagctccaa agaattttca tttgtagaca
     4021 tacagtacac ccttcccgaa tttaaatttg ttttttctgt tagccaatgg actttttttt
     4081 gcagaaaata acacaaaaag gcattcgccg caagggacga atgccgtggt accaccctaa
     4141 ttacagaagt atacatacga atcgtcaacg tcgttcagtc gacggcagta acttctgatc
     4201 ttgatgcccg taacgggggc ttccggaaac ctctactgcg gacaaaggaa tgaatccttc
     4261 tgtcggttca aggctcgact cgggagtgaa tttcaacgcg ggattgcggt acgctctcag
     4321 caattcgtac ctttctgtgg gaatccgtta aacgtctact tgtctccgtc gatgtctttg
     4381 ttcatggtat tcaaaagatt tgaccttatt ttaaacaaag taggtgcaga aggcaagccc
     4441 tgattatcag gttcagtttt cgcaccgttt tgaatcggtt ataatgtgaa cagcaacggg
     4501 acccccttgc caatctaaaa gacgtgatgt ctgaggagga attatgagca aaatcagagt
     4561 atcggcggtt caatatcacc tgcatacgat tgactcattc gagcaatttg ccctgcaatc
     4621 ggagcattat atcaaaacag cggaggaatt tggcgcggaa tttgttctgt ttcccgagtt
     4681 ttttacgacc cagcttatgt cgattggtga cagtgaaggc aaagctctga cgatcaacga
     4741 cctgccggat tttacggacc ggtaccttga attattcact tcgttcgcac gtcgaaccgg
     4801 gatgcatatt atcggtggca ctcatgtagt taggagaaac gaacgtttat ataatacggc
     4861 acatttgttt tacccggacg ggcgtgtggc cactcaggac aaaattcaca ttacaccgac
     4921 agaggtgcat gaatggaata tggctcccgg tgaggggctg aatgtgtttg agacgtccaa
     4981 gggcaccata gcgatgctga cctgctatga tattgaattt cccgaaatcg ttcgcatggc
     5041 gaagaccaag ggagcagata ttattttctg tccttcctgt acggacgatc gtcacggatt
     5101 ttaccgggta cggtatacaa gccacgccag agcggttgaa aatcaggtgt atgtcgtttt
     5161 aacggggact gtcggcgctt tgtctacggt tgattttatg cgtgccaatt atggacaagc
     5221 cgcagtcatt acacccaatg acattccttt tccgccacgc ggcattatgg tggagggtga
     5281 actgaacaac gatatgattg tgacagcaga tctcgatttg cagctgttgt acgatgtgcg
     5341 cgagcggggc tcggttacaa cctggcgtga ccgtagaaca gatttataca cagactggag
     5401 ctaatgaaag gaaataagcc atgtatcgca aagaatggtt catctttgac ggcgatcgac
     5461 cgctacgggc ggtgattcgt aattattcta cagccgatta tgaggggttg ctgcgtattc
     5521 agcaggagag cttcccccca ccttatccgc aggagctgtt atggagccgg gagcagattg
     5581 ccagccagac agagcatttt gcagatggag cgctgtgtgt ggaaattgag ggggaactgg
     5641 cgggttcggt aaccagccta ctgatgcatt ataaccccga acatccccag catacatggg
     5701 atgaagtagc ggatgacggt tatattcgta cgcactgtga ggacggcaag gcgctgtatg
     5761 tgattgattt ggcggtacgt cctgcttacc gcagattggg tctgggcaaa tggctgattt
     5821 tttccttata tcatcttgtg attgaacgga gactggatcg tttgctgggc gcggggcgta
     5881 tgcctggtta tcagcatcat gccgaccaat tgagcgcaga agcgtatgtg gatgccgtag
     5941 tgtctggtga gctgaaggac ccggtattaa cttttctgct tcgttgcgga cgggtgcccg
     6001 tttgtatcct gccgaattat ttggatgatg aacaatcgcg taattatgct gccctcatgg
     6061 aatggagaaa tccgtttcat acccatcact aattgtagag gagcgtgtcc tatcctatgg
     6121 aatatcatcg cattactcat attgaagacc ccttgtttgc gagcatgcat cagctaatgc
     6181 agagagtatt tccaccagag gaagtgctag agtacagtct gtggaaggaa ccgctggaag
     6241 acccgggtat tcgtgtcttt gttgcggtac aggatgataa ggtagttggt gcaacagagt
     6301 atcgttatta tgaggacttt aatgtagcta tgacagattt tacgatcatc ggacaatcgg
     6361 gactgggcat tggccgtttt ctttggacac gacgccagaa tgacttgcac gcgcttgctc
     6421 aggccagcgg acagcagttg ctgggtatgt ttgctgaaat ctatgaccct taccgtggca
     6481 acgagcatcc ctttggtggt gtcaagccaa tggacccgta cgtgcgacgt gaggtgctat
     6541 ctcatctggg ctataagcgt ttggatctgt actacgtaca tccgtcctgg aataacgatg
     6601 gtgtagcagt agaagggctg aatttaggct ttatgcctga ggatgatagc atggaagaag
     6661 tgagcgccaa attggtggca gctttcctac gtcgttacta tacagtattg ccgaacaagc
     6721 ctgctgtctg gaacgaaatg atagatggat tggaagccaa atcgacagta gcattgctgc
     6781 cattgtaaac atgtgaagtt caaaagggtg cactcaagcc atgtgtatca tttgtgtggc
     6841 ttgggtagca ccctttttgc attctctatc tgtcctttca ttttccttga tctctgggtt
     6901 cgggcttcgc agatgcgact cctcgtgggt tatcttcggc cgagatatca tctgtaattg
     6961 tcttgtccgc agacctgcgg tcatcctctt ccacgggatt caaggctttg tagcgcttat
     7021 actccatatc ggcttgagac atcggatctt tatacatagg agatcagtca actcctttcg
     7081 gttatacact tcattacccg catagcagaa taggtaaccg ttttccttca cctgataaaa
     7141 tgaagtgctt aatccagcat atcgtcgctg tccagttgct cttcttcgtc cccatcggta
     7201 ccattcagca aatcggtacc atgcaggaat tcggcaggag cagaagggtc aacaggactg
     7261 ttcggtgtca gttcatcggc atctgggacg tcttcgagag gagtatctgg gccctcggtt
     7321 agattctccc agttggtttc tgcattttgc agagaaggct caaaatcatt gtcatgtagc
     7381 tcattaactc gatcatcacg attggccatg ttgctcagct cctttgcttt ttgttgctta
     7441 ttccgacctt acccaaacag tagaacggct aaaccttgag ttagtgtgtc tgtaggaagt
     7501 taaaatcatg cgaataggga tatgcccatt ctcaattagc gtttttttgg taactgctgt
     7561 gatatgataa agaggatagg gagggatatg aattggaatg gtacatgttt ggtccgatga
     7621 ttagtcgtat ccgagtaggt caaaaggcat ctaccccggg attttcccgt accctcattc
     7681 ggcgcccgga aggcttatac tggacagatg gcggacaggc cggaaaaata gtagaaatac
     7741 gcgattattt attttccgat atttggacga tctatgagga tgaagattgt gaaccatggt
     7801 tggggcttag agagcagaag gagcggcgcg aacaggaaat gatcattaat caatatgaag
     7861 attttacaaa aaatgagtaa aaagaacatg ataccctact aatgaagaag gtatgcacat
     7921 catcgtatag aataatataa tttcaggacg taaaaaatgt taaaacgaat acaaacttgt
     7981 aaatcctact atgtaacttt gaggtgctta atatgaggca tgtgcccaaa gctgtcgcca
     8041 ccctgctagc ggtcattgtg ttgttgttgt cgctgggcta ctccgcctat gcggccaaaa
     8101 tgaccccgga aagggattat aagataccct cctgggatat gagatgggga gcggtaaacg
     8161 aggatggctc tttagatgag gtaaaggatt ccagcaaggc ctggatgcat attgaaaatg
     8221 atacacaact gcttaggcag cccggtaata taggctctgc ctggattcgt atgaagttac
     8281 cttcgctaaa tgatgaaacg ccagcggtgc tttttgaaaa tatttatggc aggcatatta
     8341 cgctgtataa agatgggacc aatttttacg aatcctaccg tgggtacaat tatgagaata
     8401 atcgtattct gattccgctt aagccggaag acagcggtaa aacattatac atatggacgg
     8461 aaagcagtaa gaatagactg ggcattatcg gcaatgtgat gaccggtgat tatcgtgatt
     8521 tgttggggac cttggtcaga atggatgttt tagatattgt actgggcagt acgtttatct
     8581 ttatcgccct ggtactactg atctgctcat ttttcctgtt ccgtccgagt atggccatgt
     8641 ggctgtccct aagtgcaata gtattgtcta ttggtctgat gatcgtaacg tattcaccat
     8701 tcttgtatac attctatcgc ggctatggca agctgtactt acaacttttt gatgtggcac
     8761 tatttattct gctgccttca ttagccttct tttttgaaca aaatatcaat tcgattatac
     8821 tgattcgcaa attcagaaag ttgttaaccg catactcttt gttctgcttt accatgatga
     8881 ttgtgaattt aggagcacag gagcggttga acgatatata ttattttttt agtgtagtca
     8941 tcttgggtat attactcgtc gccttattga tactgctggt atttgcttcg gttcgcatgg
     9001 cacttaaggg tgatcacgaa gcgatcattt tatcgacagg ctttgcattt tttgcagtca
     9061 tctctatcgg ggaactgagc tggttcttca ttctggacgg acactacaat atgtttttgt
     9121 ggaaatgggg cgtgttcggt tttgtactgg cgttgatcgc gatattgggc agaaggctgg
     9181 cagaaaagca caagcaggtg gttcggtact ccagagaact ggaaatgttc aataatgagc
     9241 ttcaacgttc ggagaaaatg gagattatta gcgatctggc tgcatctgta gctcatgagg
     9301 tacgtaatcc ccttcaggtt acacgtggat ttcttcagtt gatgagcaag caggaggatg
     9361 gtaaaaataa agactatcta catatcgctc tggaggagct ggatcgagct tccgcgatta
     9421 ttactgattt tctgactttt gccaagccag aatttgacca aaccaaaacg ttgaccatat
     9481 tgaacgaatt caaacatatt gaaggaatca tcagtccaat ggctaatttg caaggtggaa
     9541 aaatttcact ggatattccc caggaaatca aagtacgcgg gaattcctcc aagttcaagc
     9601 aggcgttcat caatatcatc aaaaacagca ttgaagcgct gcgagatcag ggtcatattc
     9661 atatatgggc ttatgtggac aacggagaag ctgtcattca tattcgggat aatggtgaag
     9721 ggatggatgc tcagacttta tccagactag gtgagcctta tttctcgaat aagacaaaag
     9781 gcacgggttt ggggatgatg gtgacttttc ggattattga aacgatgaat ggcaaaataa
     9841 cttttacaag tgcaaaaggg gtgggaacag aagcgaccat ccgcttcccc gtagccggat
     9901 aatatccggc tttttgcatt cggagaaaac ggagggaagc ttgctgagcc cacccacatg
     9961 agattaagga atatagatta aataagcatg aacaactaat ttaccacatc gagcgaggtt
    10021 tctgggatgc agcgagcacg ccggaggggt ctggaggaat taccagaaaa aactgatcag
    10081 gcgtttcctc taacgttttg atttggatat gatcggggat cacgactcct aacacatcac
    10141 gaattgcaga tttgggatct gtcatcagtt tctctctgaa actggcatcc tcccaagctt
    10201 tttgaatgac ttgtgtttga agaacttcag tagccatcaa aaatcaccct ctcattcaat
    10261 tggttatatt tacctagtca gtataccacg aaaggctcag aaaaatctag cattatttca
    10321 tatttttgga gagccagtag tcaagtccgc ctcttctcaa atgcgagcgt ccgccttcaa
    10381 tttccgccgc cacttcgccc agttctgctg cgatagaatg tgcaaagcta cttaggccgt
    10441 ggatagaagg ctccagggtc tctaactgtt ggactgcttg atcggcaatg ctcacatagc
    10501 tggcgagcac accgcgtaca taaatcgctt cctgaatctg ttggggtccc aatccttcac
    10561 agtaagctgt cttctgctcg gcactgatat gggacaaaag acagttatag ctatgttcga
    10621 ccaaatcttc tgaccaatcc gcccaatcat ccgacatttg aagcacgagt agcgccaagt
    10681 ccgttatatt tgtaatagtc tggatcagat cagcacggcc tgcgagcagt aaagcacccg
    10741 ttccggccat ttttaatgga cttgctttca gcgcgacctt atttctttct ccttgaaaat
    10801 agtcctctgt tccttcggat atcacactaa cggcccattc atcaacatac gttcgggcat
    10861 atgaccaaaa aggagaggtt gccggaaaaa ggtcccgata tacgcttata cactcggtat
    10921 agaagagctg gcttaaggcg agttgcattt tacggttgtc tgctgctgtg tccatcacat
    10981 catcttgaat taaatagtga gccatgataa acacgttgcc aagtgacagc ttgtggcatg
    11041 tttcgggggg gagtccggtg agttcttgca gccaaaatgg aagcaaatag catatgtaat
    11101 tacgcgtgct gtcttcccgc aacggattaa aacgcgccag aaagtttaaa ccctcttgct
    11161 gaaagggagc tggaaacgtg gacgtccgtt cctccgcttg acgaaatact ttttccaatt
    11221 cgtctttgta tgcaaaatac cattccatcg ccatcacctg catctcttat gaatattttt
    11281 atagcgattt ctagttgtta ccggccatta tacaacagat tgcaattttc aagattttgt
    11341 tatttttaca ttgagaatgt tgtgaaaaaa catagggaat gaataaaaaa agcagaaaga
    11401 gaaaatatag atgaaaaagg atgaaagaag ggtctgcaac atgaaaaaac aattgaaatt
    11461 ggccgctgct atcctatatg gaggagtgat gatgtatggt actgcgggtg cagcaggagc
    11521 ttccgggacc gaaccgggta attcgttgca aactctcact cccaacggtt ctatccaagg
    11581 ggcagcccgc caatggaatg ttgaaccaca ggacgaccac ggacatgggc atgttcacag
    11641 acatagacac ggcaaacggc ctggcggctt gaatcaccat ctcaacgaga aagtagccaa
    11701 gctgctgggc atcactcctg tccaattaga gaaagaactg ggacaaggga agtcattggc
    11761 cgaggttgct aaaagcaaag gcatccaaga agaccagctc attgataaat tgaagaatga
    11821 aatgaccgtg gatctgaaac ggcttgtgaa ccgtaaaggc ccgattacat tcgatcgtaa
    11881 gtccggggct tcgaatgaag ctcaattaaa gcgttagcca gggataccgt ggatatcttc
    11941 ctcatgaata agtcgaggag taaattgttt gacaacaaaa aaaggatggg ggaaacccat
    12001 ccttaaatta ttgcagaatt ccagacataa tgagattcca aacaacttcg aattcctgat
    12061 gaatggtcgg taataaccac tctcgactgt gaagagggtg atgaaatcgg actgttgcca
    12121 catagattcc acgcgcaacc tcttctgcta atccttcttt aaactcgtga ttgcttatcc
    12181 ctgcttctac aattttggtg atgttaccga tgatatgatt aacaaattcg ttagcaatat
    12241 catccgattc ttcagcaatt ttagtataaa ttgcaaacaa ttcgggatct tgttgggctt
    12301 tggtatgttt gatccgaatt aacgtatcca tccatataag taaacgctca ctggcagagc
    12361 attcttgttg gaatgttttg tccaaaggtt cagtgattac atgaaaccat cgttttacaa
    12421 ctgcaagacg tagagctgtt ttacttggaa aatgacggta aatggttgcg tgtgtgacat
    12481 tcaatgatcg cgccacatca actacactcg tcttctctgg cccaaatcga cgaagaacgt
    12541 cttccgtcgc gtccagaatg gcttcttttg ttagaaactg atctaccatt aatatcgggt
    12601 accagcggca gcatctgctg ggacagcctc ttgaattttc tctaaatcag atgcggtaag
    12661 ttgtaagtcg agcgctgtga cagcatcctg aagttgcgtt agacggcgag caccaataag
    12721 tgggataata tcatccccac gagatagaac ccacgaggtt gcaagtgatg caatggttgt
    12781 gtttttttct tcagcgatgg tacgtaaggc ctctactagc tccaaatttt tatccaaatt
    12841 ctcaccagta aaccgtggta aatgtttacg gaaatcgaaa ccatcagttc gacgatcttt
    12901 gtcccatgtt ccactaagta atccgtgcga gaggattcca taggctgtga tgctaatgcc
    12961 gagttctctc gctgttggta aaatctcttt ctcgatatct cttgacatca gagaatactc
    13021 gaattgcaga tctgtgattg ggtgaacagc gtgagctcgc cggagtatct ctgcatcaac
    13081 ttctgacaaa ccgatgtgcc tgacatatcc cgccttgacc atatcagcaa tggcaccaat
    13141 cgtttcttcg ataggaactg taggatccag ccgggcagga cgataaatgt ccacatagtc
    13201 agtattcaat cgtgccaaag tatacgagag ggagtttgtc acagcctgag gacggcagtc
    13261 aattcccgaa taggagccat ccggtgagat cagcatgcca aatttcacac tgaggatggc
    13321 atcttcacgc tttcttcctt tcaaagcttc agcaaccaaa agttcattgt gtcccgaact
    13381 ataaaagtcc cctgtatcta gaagcgtaac tcctgcatct agtgcagcgt gaatcgtgtt
    13441 aatactttct gcgcgatccg cagagccgta tgttcctcct gacattccca tacagcctag
    13501 acccatgctt gaaaccaatg gaccgtctat acctaatcgt ctttgtttca tttagaagac
    13561 ctccttatta agataaattg aatatactat aacaaaattc aaaatacaaa taacattttt
    13621 tgaattttgt aattctatcc gcatggaaaa ggaaggttcc cgaaatcatt gcggcttttg
    13681 aaccagagat aacaaaaaac tacacccata tcggcgtgaa aaccggtctt tttgtaatta
    13741 aaacccttta gtgttgtaaa ttatttttca aaagctcggc taggcccgga taaatttgac
    13801 cataattttc tttccaaaaa tactgggtac tttgttccat atgctgttta atatcgtagc
    13861 cagtgtgtgg acctattgaa tgcccagtat cgaaagcatc gtattctctt ttgcggatag
    13921 tgatagtgaa gccattgttg actggtttcg tcttctggaa agtgaccatg gagcggatct
    13981 ttcccagcaa agatgttatc tatcattttt tgaatcaaag ttcgtttgct tggagcttaa
    14041 ctatctttaa agagcttaaa aaaatcaatg gtttctttta aatcttcatc atccgtataa
    14101 atgtccacca ccttgcctat ttcaattgca aagtccacat acttatttgg tttagccgta
    14161 atgatattct tgtgtatctc cagacccgtt ggatgattca caggattttt ataggagaca
    14221 cctgctatct ccagaagttc agtggcagaa caaatggtcg ctatcacttt attatcatta
    14281 ttcagtgtat tgattaaagc taaaagttct tgttcgtctt taatggagtg ttatctccac
    14341 caggtataat taggagttga atatcctccg cggacacttc atcaagggct accgaaggcg
    14401 taactttaaa atcctcatag gaaatcactg ggtctttggt tacaccaatc gtaacaatat
    14461 cccctttggt tttcataaaa taggttgtct gattgttctt ttggcgtctc taatttttgt
    14521 ggtcatgggt aggagtggta attcgttcag gtttagaagt tgaaataacc agtcgccttg
    14581 aaatctacca gcgactggtt atttagcttt gctagaatat gagttgagcg atacctataa
    14641 tagcttttta agctgggaaa tacggccttg ggatacgccg agccattcag catattcgcc
    14701 ttgcttggct gttggatgct cgcgcatgag ttttcttaga ttttcgacta aatgttgtga
    14761 agacgaccga tggttacttt tttctttgta cgcaggtttc tttatgacag gaaaaggtaa
    14821 tggactcaca cctatatttc ccttcagatc gtttatgcat tttttacata aaaatgaatc
    14881 cctgaaatag cttaaatcct gaatcgaata gcataagtga cagcagactc caatatactt
    14941 ccgcatactc aataaacctg tttcaacatc taaataaaat tctaaggact caccagcttg
    15001 aatgcccata gaggttcgca tctctttagg aataacaatt cgacctaacg tatccaatgg
    15061 acgtgtcata cctgtatttt tcaagtgatc ttctccttcc attgtccaac atccaaagat
    15121 ctcctaataa aaatataaaa atcaataaag taaaagcatt tatgtttgtt ccaaaagatg
    15181 gtattatcgt gaaggaaaat caataattat actattagtt tccaaactat attgtttatt
    15241 gaaattgaaa ttttatgaaa atgctgaaag ggtggtttat ccatggaaat cacacctacg
    15301 atacaggcag aaattcaaac ctatttgaaa cgaaaaggct taacgatgac caagtttggt
    15361 cacacgattg atttgaatgt aggtacagtt agtagcattg tgaccggtaa ccgatctatc
    15421 tctgttcacc aactggatag tattactgcg ggaatgaatt taccaccgga ttatttttac
    15481 gaacgttata ttgaagaatg cattgaagaa tctccgctca actggaaaaa aattagccct
    15541 ttcttatacc gatgtattga gctaggacga ctggactgct tgcagcgagt tgtaattctg
    15601 ttattggata accctaatta tccgccatcg ctctttgaag ttgccgaaaa tgtatacaaa
    15661 gacggttaca atgaagcagc ggcttacctt tacaaaaaag tggctgaaag tgagaagcag
    15721 cagcattcag agcgattggc gatctgccag tatcgtttgt tccaaatcaa tattggacaa
    15781 gatagagcta taaatcttca agctgccatt gaatttgccc cttttgttga tcgtttagac
    15841 gagatagagc aattagatgc attaaaagat ttagcgaacg tgtacagatc cttaagtatg
    15901 tgggataagg tgtatgaatt tgcacatcaa atgggtcaaa tgggaaagat ccaatataat
    15961 ttgattcata actctaagcg aaaaggatta gagccacgaa aaaagctaag caggccactg
    16021 tttgtataca tagtttactc cgaattgctg tgtgctaatg cttgcgatgc aaaaggagat
    16081 catgaacagg cattagaaca tatccgaggt tatgccgatc taagttgggt aaaggagaag
    16141 gaccctgatt cactttattg gaagaaacaa tatcagcaat gggcgaaaat taatacttac
    16201 gtcaacaggc ttatgtccgg ggatattagt gttctccccg attacgtaga acatatggct
    16261 gccgaaaatg agatttttgc cgaattaata aacgtcattg aagtggctaa tcggtacaat
    16321 gtagatgtag accatatcct taagcgtttt gaatcccaaa ttgcagcgta tcaggtaccg
    16381 ttgtcttctg acatgtatac acaacaggtt ttaccagaag aatacgtaag attctggtac
    16441 aagttagcca agtataacct gaataaaggt agatattcat atggtttcaa atgtttaata
    16501 gatgcttttg aaaaagctgt tactcttaaa catgcacttc ttattgctaa ttgcgttggt
    16561 ttgtttgagc gttttagagc atatgccgaa cctgaaatac tagctcggta caacatgtgg
    16621 gaaagaaatg atcgaaaaga cggatttgca atttgtagcg actaatttct acttgtattt
    16681 gcactaccag ttccaactgg aatcccaagc tctaacacaa tccaagttca aggacatgtt
    16741 ggtacagctt aaacaatttt atttttttat gggccagctt atcgctggtc tatttttttt
    16801 tgtattattt tgtaattttt tagttcaaaa aagatcatga cgtatttgta catccctcct
    16861 taaaatgaga ttcattagga ggtatgcagg atgaacaggt atgaaacagt tacgttaatt
    16921 caacaggtgg aaaacgccag acaacatttg catgatcttt acgaagagta tggtttcgga
    16981 catgcttgtg tacttgagca gtctatgctt ttggatgaac tgattaatca gtacaaccgt
    17041 atgtttcaga ccaagaagct acctcattat gtttagtcca tcctctccct actttgttat
    17101 gcaaaactat gacttctccc gcgtaacgtt tattattcta tataatgact tattttaaaa
    17161 taaaatacat attcatgtca taaaatgtta atcatctttt tgaggggacg gcatactaag
    17221 gcacagaaaa gcagagctca ataagtgagc cccgccaaag ttcattggaa tcataacccc
    17281 atgctgaaac acagacgcat aagattagcc aagctcctgc gtgcttttgg aagcgcgttt
    17341 ggaggaaagg aactggaaac gaaaggagtg ccagttcaat cgctgtctgc ctttggagcc
    17401 aacaatccag ttaccgccgg gcagatgggc aaaaagccag ctgatgccca gagaaacact
    17461 tgccacgacg ataaacgtaa tgagcgtagc tgtaaaatga tgatcgccca gtgcaagcga
    17521 gcgggtgtag taggatatga aggccagcac gagcgcatga gctagatatc ctccaaaaga
    17581 ataacgcccg atccagttca acatacggcg aaacggctcg gatcgtgtat ctttttgcaa
    17641 atggagcagc agtccgtaca ataaaagcag ctgcgagaca atgagcacaa aggtacttgg
    17701 cttcaaatag gtggaaatat taagattgat cgtatcgccc gattggatca gcatcgtgtg
    17761 acccatgagc atgaacaaac caataaacac aaatacattc cacggcaacg tctgcttggc
    17821 cagtccacgc caggtgtctg tcatgtaagc acatactgcg cccagcataa aatagaaaaa
    17881 gtacatgaca aagttatagg tgcgataatc cagcagagtc tgccaaaagg acggcaaccc
    17941 agtgctccat gcagacatgt catagtagga ccattgtaac agcaaagcat aagccgtagc
    18001 ggcaatcagc ataatagcca aaacaagctg tttgcgtctt ttcgtgctgt aacgacgtag
    18061 aaacgcttga accttcccgg ttgcttttga aaataaagga aacaaaatat aaaactgaaa
    18121 gatcatcact acaaaccata gatgatatcc gctgacgggg atgatcattt cctcgaacat
    18181 acctttataa aagtaaatat atccccactg cgccgttgac cagttttgag tacacaccca
    18241 ataaataaca gtccagcaaa ggaaaggaac ataaatatct cgaaaccgcc tgccaatata
    18301 gcgaggatag ccaatcggtt tgttgccgtt ataaaaaagc agcgccgcag acaggaaaac
    18361 gaacgtcggt gtgccaaaac gtgtcaaatg atacagcatc gcgagcataa cagaatctgg
    18421 ctgttggatg tcgctgcgat aaatatattc gccaatgcaa tgctgaagca cgacagcgag
    18481 gtaggcaagg ccccgtagtt ctgtccactc cgcgatacgc ggcttgctca tccatatcac
    18541 tccttttccg caagatatgc acatgttttt cctagcacaa ttgtaggtat tgtaacgtag
    18601 aaacattagt gcaggattaa cgccacctga aagtaagaag agtgaagtag ttccaattta
    18661 atatgattgc gtttacaatc taagtaaaac cagaataaat taaagtgaat ttataactta
    18721 aggatacaca caggaagagg agaggaagga tgaaaaaaac gctgctggta tatatgctgt
    18781 tgattgcggc ctttgctctc tatgtgttca ggtatgaaca atctggcccg ttgaatggca
    18841 cttgggagga taaagggctg cgaggcagta tcggagagac ctatataatg attacgttcc
    18901 agtccggttt ggagtattgg aaaagcgggc tcaagggctt cgaggatgcg ggtgatgctt
    18961 tgggggtgac tgtggagtat cggggagcta cccgttatga tgcgcaggag cagacaactg
    19021 ttattgagca ggcgattgct cgtaaacccg cagggattgc catatcagcg attgatcctc
    19081 actccctgat tccggtgatt aataaggcgc tggatgcggg cattcctgtg gtattgtttg
    19141 atgccgaagc gccggggagc cgggcgtatt cctttttggg cacggataat tataaggcgg
    19201 gcgtgaccgc tgcggataaa atggcagagc tgttgggacg agaaggtcag gtcgctgttc
    19261 tgacgctgcc tggacagcaa aatcatgagg aacgctcgcg tggctttcgc gataccattc
    19321 aacggcagta tcctgcgatg aaggtggtgg aagtcgcaga tggccgcgca gacgcgatgg
    19381 tctcccggga tgagtcgcaa aggctgatga aagcttatcc gaaactggcg ggcatttttg
    19441 tgaccgatgc aacgggagga acaggtgtgg gtgaagcggt actgagtcaa aaaaacagcc
    19501 atccgctgaa aatcatttct tttgatacga ataaagcgac actggatatg attcgtggtg
    19561 ggacaatctc ggcaacgatt gcccagggaa catggaatat gggttattgg tcgcttcaat
    19621 atttgttcca tctgcatcat cgtttaacga ttcctgcccc ttcttcctct ggagacaaca
    19681 ctccgttgcc cgtgcgggta gatactggga tttccgtagt cacccgggca aatgtagatg
    19741 attattatgc gaaataaatt ttgggagcgt atccaattag gggtgcgcca aacgataccg
    19801 cggttacgct tgcgcaatat gcctttacgt tatcagctca tgctgctgtt cttgttgttt
    19861 ggcattgtgc cttcgctggg attaggtcta ctggtcaatt ggacggtgga acggattatt
    19921 gagcggcagg tggaagatca tacgatgcag ttgattggca aggtgaacga agcgctggat
    19981 accaaaatgg aaaatttgca aaacatgacg tatctgattg cttttaaccc cgatatcggg
    20041 gagttctgga aagggaagac gctggctgac ggccacgcgg gtcatgcgag tatcgtaacg
    20101 ccggaaaacc agactctcac ttccaagcag gcattaagtt ctgtacagga gcaggatacg
    20161 ctgtataaaa tgaagcaatt tttgcagggc tataccacgt tatatcctga aattgcaggg
    20221 attctgatcg tgaacga
//
