LOCUS       NZ_JANAVN010000003     21404 bp    DNA     linear   CON 26-JUL-2024
DEFINITION  Paenibacillus sp. Lou8.1 NODE_3_length_379416_cov_157.274757, whole
            genome shotgun sequence.
ACCESSION   NZ_JANAVN010000003
VERSION     NZ_JANAVN010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. Lou8.1
  ORGANISM  Paenibacillus sp. Lou8.1
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 379416)
  AUTHORS   Gonzalez-Pimentel,J.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAY-2022) Agroquimica, Microbiologia Ambiental y
            Conservacion de Suelos, Instituto de Recursos Naturales y
            Agrobiologia, Av. Reina Mercedes 10, Sevilla 41012, Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024213565.1-RS_2024_07_26
            Annotation Date                   :: 07/26/2024 02:53:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,316
            CDSs (total)                      :: 5,255
            Genes (coding)                    :: 5,159
            CDSs (with protein)               :: 5,159
            Genes (RNA)                       :: 61
            rRNAs                             :: 3, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4, 2 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 96
            CDSs (without protein)            :: 96
            Pseudo Genes (ambiguous residues) :: 0 of 96
            Pseudo Genes (frameshifted)       :: 40 of 96
            Pseudo Genes (incomplete)         :: 74 of 96
            Pseudo Genes (internal stop)      :: 9 of 96
            Pseudo Genes (multiple problems)  :: 25 of 96
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:00:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 237462
            Orig. end                         :: 258866
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JANAVN010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21404
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..21404
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21404
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11404](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11404)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     gene            complement(777..1673)
                     /locus_tag="NLX78_RS05940"
                     /old_locus_tag="NLX78_05930"
     CDS             complement(777..1673)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014278738.1"
                     /locus_tag="NLX78_RS05940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_05930"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_134904268.1"
                     /transl_table=11
                     /translation="MLKKRGTWGDKGSKLEFGLFTLPVILCITIAFYIPFLMTIRYSLT
                     KWNGISKHPKFVGLDNFKQILLGDANFAHAAWFTVKYAILYIVLVNVLAILLALVLDMK
                     LKSSAWLRAAFFIPYILSLVIVGFIWKFIFMQGFESLGHSTGWGIFQLSWLGEEGLAFI
                     SILAVSIWQSIGFYMVIYIAGLQSVPEDLKEAAIVDGAGPIRRFFSIILPMLAPSITIS
                     VFMALTNSIKVFDVILSLTGGGPGGTTYSIAYDIYRDTFQNNLYGYGTAKALILFVAVL
                     IITIIQLSIFKRREVEA"
     misc_feature    complement(1656..1672)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.51"
                     /tool="antismash"
     gene            1796..3655
                     /locus_tag="NLX78_RS05945"
                     /old_locus_tag="NLX78_05935"
     CDS             1796..3655
                     /EC_number="2.7.13.3"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822646.1"
                     /locus_tag="NLX78_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_05935"
                     /product="sensor histidine kinase"
                     /protein_id="WP_254349953.1"
                     /transl_table=11
                     /translation="MCTLSKGAIIMMSERVGTFLRSMWRRITQKLVNKLILLFTSVIIL
                     VVGSLTIISYQMIEKESVNHSIASTTNNLLLVNQNLEDYLEGMQQLALPQLRYNDIMNA
                     IANENRDYASRMVIENYLRSMFYSRNDLEAIYLYVADRHQYYVVTRETYNITVRKGINT
                     DIPKLPWYKEAMASTTNESFQSFVGSRSDMGYVAPQASFMAYHRVLRSIASRHPQAVLS
                     FYYNTSAVNEIMQNIPLGKGDQLMLMSPKEVPFYVNSFPLYERMRDSGVLSQIGKGGSG
                     RVTWSDSSGDQEYLVVYDAGEKEGWQLIKPIPYRQIYEAATTTRNWSYAIGALFLGVSI
                     ILVTLTSNAITRPLHKLSTQMKRFSTGDFGATAPVKGHDEIAYLSLHFNEMVQRTEELI
                     NERYRMKLVEKNAILKALEAEINPHFLYNALQAISTQALKREMFDMADMVDALAQTLRY
                     SINGKDIVVAREELKHIERYIGLQKARFGARLRVEVVWEETLMELPIPRLSVQTLVENA
                     IKHALEKVSSDILIVISAESSSTNATITVRDNGPGISEDKLKMVLDSFHEKWEERESEH
                     IGLKNLNTRLKLLYGDQAGLFILTDETGTEMRMQIPRGGVSHV"
     misc_feature    complement(1844..1857)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.7"
                     /tool="antismash"
     gene            3648..5300
                     /locus_tag="NLX78_RS05950"
                     /old_locus_tag="NLX78_05940"
     CDS             3648..5300
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688966.1"
                     /locus_tag="NLX78_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_05940"
                     /product="response regulator"
                     /protein_id="WP_254349879.1"
                     /transl_table=11
                     /translation="MYNVLIIDDEEPLREAIRIIGDWDGLGIEHIYEATNGRLGLELLG
                     QHHIDVVMVDMKMPELNGIEFLRAIEKAYPHLLTIVISGYNDFEFTRQAIQSRVVDYLL
                     KPINRQDLNQALRKAVDILESREQSKNKFISQNITLNMSLPKLKEKLYLSILDGSFKRQ
                     ANTALLPLIGADQPGNRFGVIVLRLLNRDEIRRTRFHGDADLMDFAVTNVLAQTSDERL
                     SCFSFSHPRREREVVSICTLAPGQEEHMALLLAQVTQKAVANLHGLFSMVVVAGLGKLC
                     TDVLELASAYMDAKTLIHSTDVLKLEGESILHTVPRQMGTLEEMSWTERLLSIQKDAQT
                     GQANRAKVLLGDLLKQLASGPIFRLQDADRMMKEFHFLLREAAIELGASTSASALNQDG
                     ALEEPEQVGESDLSADFTSFVHYGQRLNRMLELYIAGVQHAQAGNQPFDITDIKRHIDR
                     YYFEDIKISFFAETYFLSREYLMKLFKQQFGYGIHEYVQKVRMDKAKELLGDSSLKIQE
                     ISDMLGYKDKNYFSKAFRNYYQVSPSEYRVSLQ"
     gene            5407..6711
                     /locus_tag="NLX78_RS05955"
                     /old_locus_tag="NLX78_05945"
     CDS             5407..6711
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014278735.1"
                     /locus_tag="NLX78_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_05945"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_254328115.1"
                     /transl_table=11
                     /translation="MLKKMMALSGSLLLTVGLLSGCGSNGGTDASKESAGGKEDLKTVT
                     INMFTASPEYTDAFNAYIEEYKKVKPNVKINLEIMQADYNTILKSKIASGSTPDVFQTT
                     AGGDIDTYADYSADLTNEPLAAAMTDAVRANMSSSDGKVLGLPVKGNLFTLIYNKDLLT
                     KAGVTSPPKTIAEMQDAVTKLEAKGITPFANAYKEWWVWKHIFQHYVDAAAQDAGVEPK
                     QLVSDFIAGKAKIKDYPVLYNNFFNFIDLTVKHGTDKPLERDSNAEVSDFASGKAAFMT
                     GKGAWDEEAIKKINPDLKIGIMGYPVSDKADQSVIITGADQALRINKDSEVSKETIEFF
                     NWLYTSEYGKNWFSQVAKVIPPIKDAPLPDLEMPKEMESILKTSKSGDLSVNYSLDTFH
                     QKFGELMQAYISGNMNKDQAVAEIEKAWVQLGSAQ"
     gene            7031..8059
                     /locus_tag="NLX78_RS05960"
                     /old_locus_tag="NLX78_05950"
     CDS             7031..8059
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312578.1"
                     /locus_tag="NLX78_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_05950"
                     /product="NADH:flavin oxidoreductase/NADH oxidase"
                     /protein_id="WP_254349880.1"
                     /transl_table=11
                     /translation="MTNSLFTPYTLKDLELKNRVVMPPMCQYSVTAKDGIPNDWHHVHY
                     LSRAIGGTGLIIIEMTDVEPDGRITDYDLGLWSDEHIPAYKKLVDGIHAHGSKVGIQIA
                     HAGRKAEDAAEPVAPSAIAYPDANYKQPRALTTEEVRGMVQKFADATRRAVQAGVDTIE
                     LHGAHGYLIHQFHSPVTNKRDDEYGKDLSRFGVEVIQAVRKQMSAGMPLILRISAVEYV
                     DGGYDVDHAIELSRAYQAAGVDVIHVSSGGEGPAGARKPGNYPGYQVPFARQIREALNI
                     PVIAVGSLDDPALAQSIIGNEDADLVAVGRGLLRDPYWAIHAAVTLRGEEPSIPEQYQR
                     GY"
     gene            complement(8154..9884)
                     /locus_tag="NLX78_RS05965"
                     /old_locus_tag="NLX78_05955"
     CDS             complement(8154..9884)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688963.1"
                     /locus_tag="NLX78_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_05955"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_254349881.1"
                     /transl_table=11
                     /translation="MFQLIRKYIKPLLALQITVLCIIIINILFMIYQPILMQRLIDSYN
                     TETLSAKEISYLGSLFLLLLVGGGFTGALRDSVIFKIKNLLQFRLRNDIYQQNLNLRSH
                     QPTGKIISLLYNDVEALTGLLNQAFIAMFTDCLTIVATVVVLYFMNWKLATVSLIFIPI
                     YFFLYYNSKKKVYQLNVAYKKQYENMTETLQLGLKQKWTAIRFNRQKYSSALFCREQIL
                     LVRILKKLFARELLLGIISNFLSGFFPLLLLAIGGFLLIDREITLGTLVAFSTYIVKLL
                     QPVSRLSQLNVGVQSAVASAERILNFFNLNDVWNGTNIEGFTGNGIYVKNVFFSYNNLT
                     PVLDDISFEIKKNQMLGIVGESGSGKTTIVKLLTGEVIPTKGEIYYGDNRLHDLNKNYF
                     YKNIAVVTQEELLTTGTIFDNIAFGNKNATLDEVVNISKKVGLHDYISSLPEKYNTNII
                     SGKYDLSVGQKQRLAIARALLHNAPVLILDELTSALDAETESLILHLLNELKGKRTIII
                     IAHKFQTVIHADHILVVQNGRIVEQGSHADLMSYSSTYSNSYRKQKDFLQNEVQEPSYK
                     "
     gene            complement(10001..11404)
                     /locus_tag="NLX78_RS05970"
                     /old_locus_tag="NLX78_05960"
     CDS             complement(10001..11404)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Quinohemoprotein_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688962.1"
                     /locus_tag="NLX78_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_05960"
                     /product="radical SAM protein"
                     /protein_id="WP_254349882.1"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 3.7e-10,
                     bitscore: 34.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Quinohemoprotein_rSAM_RRE (E-value: 4e-12,
                     bitscore: 40.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 7.9e-68, bitscore:
                     223.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.2e-15, bitscore: 50.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 6.2e-13, bitscore: 43.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.6e-18, bitscore:
                     61.3, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANLIQDKKDEIIHFHPYKLFEVDSKTFFYNVVTNAIFEIDSLII
                     DILHSKGKTEEHVVKDLAERYELSQVREAIQNMKEAYIIATDTNISDVEKMGILDNSQR
                     VFKLSSLTLFMVQECNLRCTYCYGEEGEYNQKGKMTSEIARSAVDFLIQQSGEIEQLNI
                     TFFGGEPLLNFPLIQETVQYVHEQSEIHNKKFSFSITTNGTLITPKIKNFFYKHHFAVQ
                     TSIDGDEKTHNFNRFFKGGQGSYDLLLKRTEEMRNDRKIGARGTVTPAELDLSKSFDHL
                     VKLGFRKIYLSPALYSLSDEHYDTLSKEMVKLVEQFRELLEREDYVTAKKMSNVLGMLS
                     KIHSGGPRIHFCGAGTNAAAVDVRGNLFPCHRFVGEDECSIGNLFDEDPLSKQYNFIEN
                     STVRNRTTCSKCWAKNLCGGGCHQENFAENGNVNQPVGKLCKVTKNFINATIKLYLQLT
                     QEQRSILFG"
     aSDomain        complement(11135..11359)
                     /aSDomain="Ranthipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a
                     ranthipeptide/SCIFF cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_NLX78_RS05970_Ranthipeptide_rSAM_RRE.
                     1"
                     /evalue="2.90E-11"
                     /identifier="RREFam024.1"
                     /label="NLX78_RS05970"
                     /locus_tag="NLX78_RS05970"
                     /protein_end="90"
                     /protein_start="15"
                     /score="34.4"
                     /tool="antismash"
                     /translation="HPYKLFEVDSKTFFYNVVTNAIFEIDSLIIDILHSKGKTEEHVVK
                     DLAERYELSQVREAIQNMKEAYIIATDTNI"
     aSDomain        complement(11144..11353)
                     /aSDomain="Quinohemoprotein_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a
                     quinohemoprotein cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_NLX78_RS05970_Quinohemoprotein_rSAM_R
                     RE.1"
                     /evalue="3.20E-13"
                     /identifier="RREFam023.1"
                     /label="NLX78_RS05970"
                     /locus_tag="NLX78_RS05970"
                     /protein_end="87"
                     /protein_start="17"
                     /score="40.6"
                     /tool="antismash"
                     /translation="YKLFEVDSKTFFYNVVTNAIFEIDSLIIDILHSKGKTEEHVVKDL
                     AERYELSQVREAIQNMKEAYIIATD"
     misc_feature    11423..11437
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.58"
                     /tool="antismash"
     gene            complement(11497..11646)
                     /locus_tag="NLX78_RS05975"
                     /old_locus_tag="NLX78_05965"
     CDS             complement(11497..11646)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037957.1"
                     /locus_tag="NLX78_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_05965"
                     /product="freyrasin family ranthipeptide"
                     /protein_id="WP_181016525.1"
                     /transl_table=11
                     /translation="MLKQINVISGVKEPILAYGCPKNDDCYYCDLKDYCRSCDAMDFCI
                     SSDT"
     gene            complement(11683..11832)
                     /locus_tag="NLX78_RS26695"
     CDS             complement(11683..11832)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037957.1"
                     /locus_tag="NLX78_RS26695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="freyrasin family ranthipeptide"
                     /protein_id="WP_367987770.1"
                     /transl_table=11
                     /translation="MIKQINVIAGIKEPIRSYGCREVDYCTFCDTRDYCGICDQSDFCV
                     TSDT"
     misc_feature    12061..12077
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.54"
                     /tool="antismash"
     gene            12134..13060
                     /locus_tag="NLX78_RS05980"
                     /old_locus_tag="NLX78_05970"
     CDS             12134..13060
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312575.1"
                     /locus_tag="NLX78_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_05970"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_254349883.1"
                     /transl_table=11
                     /translation="MDYIIETKKLRKQFGGAVAVDDISLHVERGSIYGFLGENGAGKTT
                     TIRMLMRLIEPTSGEVFLFGERLEKNYPSIFSKIGTIIETPGLYENLSARDNLRICCMY
                     MGVQDDGRIERTLTTVGLEHTGKKKFKNFSLGMKQRLGIARALVHDPELLILDEPTNGL
                     DPSGIKEIRQLLKRLCEEEGKTILISSHILSEIQQLATHIGIIHNGKLLAEDRLSRLEE
                     GFEQYTDVKVDDAEAVQAFLQEHMKQLQSNVISPQQLRIHSQIENTAALNKQLIDHQFS
                     VYEIHTSKQTLEEYFLTLISGEDGRRD"
     gene            13044..13763
                     /locus_tag="NLX78_RS05985"
                     /old_locus_tag="NLX78_05975"
     CDS             13044..13763
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016324886.1"
                     /locus_tag="NLX78_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_05975"
                     /product="ABC transporter permease"
                     /protein_id="WP_254349884.1"
                     /transl_table=11
                     /translation="MGDVIRAELIKLKGSKAFLLSYIILLAVVLLEFATSAIFYRYSID
                     KRGWTYYFEGIVLFVNVAAGFISYYILTGHIFAREYQENTHLFMFTTPVTRVKFYFSKL
                     IIIYGFIIVSLFLVLFLSALLGMSITDRPLTMAIWVYQIQVFAKMCVMHAMLIPIASFF
                     AIRWKSIMVVVLVVCTAIFLNFIYKSEWYPWIVPYLLSPNERNATIPTNVSVAWFSLSV
                     TFLLGLLLSIWTYQRKE"
     gene            13792..14526
                     /locus_tag="NLX78_RS05990"
                     /old_locus_tag="NLX78_05980"
     CDS             13792..14526
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312573.1"
                     /locus_tag="NLX78_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_05980"
                     /product="ABC transporter permease"
                     /protein_id="WP_254349885.1"
                     /transl_table=11
                     /translation="MLDLFKAECLKLKGTKIVWLSVMILVLTIVLEFYSYADSPKYSID
                     RDGWNDYFMSVVILINFLTGYMSYYILTCYIYAREYQEKTHIALFTNPIRRTRIYFSKL
                     LVIYMYIAVSLLMAFVLSTVLGTFITTRPLTFEIVMYQLGVFAKMILMHAMLIPIITFF
                     AIRWKKFVPAIMGMCTVMCLNFVLVNTPGNTFYPWTVPLLFSPHGQMGRTFTYVPGGVI
                     SIFFIFVLGLFLALRSYVRIEK"
     CDS             complement(14732..>16832)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822652.1"
                     /locus_tag="NLX78_RS05995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_05985"
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="WP_254349886.1"
                     /sec_met_domain="Alpha-amylase (E-value: 5.1e-80, bitscore:
                     263.8, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SGYAKITVDIGSASQLEAAFNDGNNGWDSNNTKNYSFSTGTSTYT
                     PGNSGNAGTITSGAPAGTIPGDGGGTTNKVTVYYKKGFNSPYIHYRPAGGSWTAAPGVK
                     MQDAEISGYAKITVDIGSASQLEAAFNDGNNSWDSNNTKNYLFSTGISTYTPGLNGAAG
                     SIRTGTPSGSAVSVGTSTYATDLNEVTGPIQTVELSGASLNVGTSTYVPNSNGVEVTIQ
                     TEAPSSAFTPIDLNTLSKPTSLNTDWSKQSIYFIMTDRFSNGDPSNDNYGGFNSNNSDQ
                     RKWHGGDFQGIINQLDYIKNMGFTAIWITPVTMQKSEYAYHGYHTYDFYAVDGHLGTMD
                     KFKELVGKAHDKNIAVMLDVVPNHTGDFQPGNGIAKAPFDKADWYHHNGDITGADYSSN
                     NQSKIENGDVAGLDDLNQDNPATANELKNWIKWLLNESGVDGLRVDTVKHVPKGFLKDF
                     DQAANTFTMGEIFHGDPAYVGDYTRYLDAALDFPMYYTIKDVFGHDQSMRKIKERYSDD
                     RYYRDAQTNGVFIDNHDVKRFLNDASGKPGANYDKWPQLKTALGFTLTSRGIPIIYQGT
                     EQGFNGGEDPANRENMNFNANHDLYQYIAKLNSVRNNHPALQNGNQKEKWVDDSFYSFQ
                     RSKNGDEAIVLINNSWSSQTRTIGNFDNLSNGTRLTNQLSNDSIQINNGSITVTLAPKE
                     VKVFTK"
     gene            complement(14732..>16836)
                     /locus_tag="NLX78_RS05995"
                     /old_locus_tag="NLX78_05985"
     assembly_gap    16837..16936
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<16937..18422)
                     /locus_tag="NLX78_RS06000"
                     /old_locus_tag="NLX78_05990"
     CDS             complement(<16937..18422)
                     /GO_function="GO:0016161 - beta-amylase activity [Evidence
                     IEA]"
                     /GO_process="GO:0000272 - polysaccharide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822652.1"
                     /locus_tag="NLX78_RS06000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_05990"
                     /product="family 14 glycosylhydrolase"
                     /protein_id="WP_254349887.1"
                     /transl_table=11
                     /translation="MTLYRSLWKKGCMLLLSLVLSLTAFIGSPSNTASAAVADDFQASV
                     MGPLAKINDWGSFKKQLQTLKNNGVYAITTDVWWGYVESAGDNQFDWSYYKTYADAVKE
                     AGLKWVPIISTHKCGGNVGDDCNIPLPSWLSSKGSADEMQFKDESGFANNEALSPLWSG
                     TGKQYDELYASFAQTFASYKSIIPKIYLSGGPSGELRYPSYYPAAGWSYPARGKFQAYT
                     ETAKSAFRTAMNEKYGSMDKINAAWGTKLSSLSQINPPTDGDGFYTNGGYNSTYGKDFL
                     SWYQSVLEKHLGVIGAAAHKNFDSVFGVRIGAKISGLHWQMNNPAMPHSTEQAGGYYDY
                     NRLIEKFKDADLDLTFTCLEMSDSGTAPNYSLPSTLVDTVSSIANAKGVRLNGENALPT
                     GGSGFQKIEEKITKFGYHGFTLLRINNLVNNDGSPTGELSGFKQYIISKAKPDNNGGTG
                     NKVTIYYKKGFNSPYIHYRPSGGSWTAAPGVKMQDAE"
     gene            complement(18730..20898)
                     /locus_tag="NLX78_RS06005"
                     /old_locus_tag="NLX78_05995"
     CDS             complement(18730..20898)
                     /GO_function="GO:0046559 - alpha-glucuronidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0045493 - xylan catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426123.1"
                     /locus_tag="NLX78_RS06005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NLX78_05995"
                     /product="alpha-glucuronidase family glycosyl hydrolase"
                     /protein_id="WP_254349888.1"
                     /transl_table=11
                     /translation="MSKIMDMPKESGYAAWLHYSRNSKVEKLPAWCRVIVVHETDEVLQ
                     SAASELQHGLTSMFGQQPKISAVPVNAPFIALGTFPAHPLVAERFSAAEQAEVGAEGYR
                     IRGIEMPDPAYSASHGNDEFKGQYVTVAGQTSKGVLYGVFHLLRYLQGGLDGKLKPTTE
                     SLHAPILDQLSNPVNPIRMINHWDNMDGSVERGYAGGSIFYDNNAFTTNMERLRDYARL
                     LASVGIQALSINNVNVHLVETELITAKFLPDVAKVAAVFRAYGIQIYLSINYASPIQLG
                     GLTTADPLESAVAEWWQTKAQEVYAAVPDLGGFVVKADSENRPGPFSYGRHHADGANML
                     ADALQSYGGRVIWRCFVYNCKQDWRDRKTDRARAAFDHFKPLDGLFRENVILQIKNGPM
                     DFQVREPVSPLFGALESTQVLLEFQIAQEYTGQQKHLCYLVPQWKEVLDFDTYAQGKGF
                     TIKRIVSGALHSPKHTNYGIAAVSNIGADTNWTGHLLAQSNLYGYGRLAWDPDLSADEI
                     ADEWVRLTFGRQGNSDGDTDLISTVKQMLLNSWNIYESYTAPLGVGWMVSPDHHYGPDV
                     DGYEYSMWGTYHFADCRGIGVDRTSATGTGYAGQYFSPNTNIYESMDTCPDELLLFFHH
                     VPYTHLLHSGQTVIQHIYDTHFEGAERAAHLRDTWVSLRGQLNDAMYEQVLERLEHQTE
                     HAKEWRDRINTYFYRKSGIPDQKNRPIY"
ORIGIN
        1 aataaatacg atgatcgaag gcagaacagc cattaccatc gcggtcatgg cgtattgcca
       61 gtctgacgta tactgtccga caaaggtata ggcggccagc gtcagcgttt tggtgctggg
      121 tgagccgttg accatgagta acggaagcag aaaatcgttc caaatccaca tcacgtcgat
      181 aatgacaatg gtggcggtga ctgatttcag caagggaaaa atcacggaaa agaaaagccg
      241 gaagcccgag gccccatcga ttttggcgct ttcatcaatc tcagccggaa tacctttcac
      301 gaagccgtga tagataaaca ctgccagcgg tgcgccgaag ccccaataca ggaagccaag
      361 tccccaagtg ctgtctgcca gatttaggtc tttcgccagt cgcaagacag tgagcatgat
      421 ggactgaaat gggatcagca tcggcataat gcacagcatg taaatcacgg agctccattt
      481 gcttttggtt cttgccagct tgtaggctgc gatggaagat atcagtacga tacctgccag
      541 tccgacgacg gtgataatgg tgttattcag aaataggcgc ggatagtcaa tgaatttcca
      601 tacatatacg tagttatcca gcgaaagctg cttgggcagc gcaataacgt cggtcatgac
      661 ctcagcgaaa cttttgaacg aattgttaat ggcgagaaac agcgggtaca aaaataacaa
      721 tgataataca atcatgcccg cttctagcaa aatacgtccc gtacggctgc gttgcatcag
      781 gcttcaacct ccctgcgttt gaaaatagac aattgaataa tcgtaatgat caggactgca
      841 acgaataaaa tcaatgcttt ggctgttccg tagccataca gattgttctg gaacgtgtcc
      901 cggtaaatat catacgcaat actgtatgtc gtaccacctg gtccgccgcc ggtcagagat
      961 aaaatgacgt caaacacttt gatcgagttg gtcagtgcca tgaagactga gatcgtaatg
     1021 gaaggtgcga gcatcggtag aataatactg aaaaatctcc gaatcggccc cgcgccatcg
     1081 acaatggcag cttcttttaa atcctctggc acagattgca agcctgcaat ataaatgacc
     1141 atgtaaaagc caatggattg ccagatcgat accgccaaaa tggaaataaa cgcgagccct
     1201 tcctcaccca gccagcttag ctggaagatg ccccagcctg tactgtgtcc cagtgactca
     1261 aagccttgca tgaagatgaa tttccatata aagccgacaa tcacgagact gaggatatac
     1321 gggataaaga aagccgcccg cagccaagcc gagcttttca gcttcatatc gagaacgagc
     1381 gccagcaaaa tggccagcac attcaccaat acaatgtaca gaatggcgta cttgacggta
     1441 aaccaggctg catgtgcaaa attggcgtcc ccaagcagga tttgcttgaa gttatccaga
     1501 cctacaaatt tcggatgttt ggatatgccg ttccacttgg tcagggaata gcgtatcgtc
     1561 atcaaaaacg gaatataaaa tgcaatcgta atgcacagga ttacgggcag tgtgaataaa
     1621 ccgaattcca gtttactgcc cttgtcgccc caagttcccc tttttttcag cataacgcac
     1681 ctctttttct caacattttc cgctctttcg ctccaagctg tttaagatat aatgaaagta
     1741 taggatagcc cctagggccg gaccaatgga tttaagaaaa cagttgaggg taaaaatgtg
     1801 tacgctttca aaaggggcga ttatcatgat gtcagagcgt gtaggaacgt ttcttcgctc
     1861 tatgtggagg aggatcacgc aaaaattagt gaacaagctc attctacttt ttacctcggt
     1921 gattattctg gtggtgggct cactcacaat tatttcctat cagatgattg aaaaggagtc
     1981 ggttaaccat agcatcgcca gcacgaccaa taatctattg ctggtcaatc agaatttgga
     2041 ggattacttg gagggaatgc agcagttggc tcttccgcag cttcgttata acgatatcat
     2101 gaacgccatt gccaatgaga atcgagacta tgcttcgaga atggtcattg aaaattactt
     2161 gcgcagcatg ttttattcac gtaatgatct ggaagcgatc tatctgtacg tggcggaccg
     2221 acatcaatac tatgtggtca ccagggagac atacaacatt acggtgcgca aaggaataaa
     2281 cacggatatt cccaagcttc cctggtataa agaggcgatg gctagtacca cgaacgaatc
     2341 atttcaatcc tttgtggggt cccgctctga tatgggctat gtggcaccac aagccagctt
     2401 tatggcatac catcgagtgc tgaggtcgat tgcatcccgc cacccgcagg cggtgctgtc
     2461 cttttattac aatacgagcg ccgtgaatga aatcatgcag aacattccac tgggcaaagg
     2521 ggaccaattg atgctaatga gccctaaaga ggttcccttt tatgtgaaca gctttccgct
     2581 atatgagcgg atgcgtgatt ctggagtgtt gtcacagatc ggcaagggag gaagcgggcg
     2641 agtaacgtgg tcagatagca gtggggatca ggagtatttg gtcgtctatg atgctggtga
     2701 aaaagagggg tggcagctca ttaagcccat cccataccgc cagatttatg aagcagctac
     2761 gactacacgg aattggagct atgccatcgg agctttattt ttaggtgtgt ctattatatt
     2821 agtgacactg acctcgaacg ccattacccg acctttacat aagctgtcca cccagatgaa
     2881 gcggtttagc accggagatt ttggagcaac agctcctgtg aagggacatg acgagattgc
     2941 atatttgtcg ctgcatttta acgaaatggt acaaagaacc gaagaactta ttaatgagcg
     3001 ctatcgcatg aagctggtcg aaaagaacgc catactcaag gcgttggagg ctgaaattaa
     3061 tcctcatttt ctgtacaatg ccctgcaagc catatccacg caggcattaa agcgggagat
     3121 gttcgacatg gcggatatgg tggatgcgtt ggcccaaacg ttgcggtatt ccatcaacgg
     3181 caaggatatc gtagttgccc gcgaagagct caagcacatt gaacggtata taggtctgca
     3241 aaaagcaagg ttcggagcga gactgcgagt cgaagtggta tgggaagaaa cgctgatgga
     3301 gctgccgatt ccgagattat ctgtgcagac gttggtggaa aacgctatca agcatgcgtt
     3361 ggaaaaagta tcaagcgata ttctgatcgt catttcagcc gaatcgagtt ctacaaatgc
     3421 cacaattaca gtcagggaca acggacctgg aatttcagag gacaagctga aaatggtgct
     3481 ggattcattc catgaaaaat gggaagaacg ggagagcgag catattggtt tgaaaaatct
     3541 gaacacacgg ttgaagcttt tgtatggaga tcaggcagga ttattcatac ttacggatga
     3601 aacgggaacg gaaatgagaa tgcaaattcc ccggggagga gtcagtcatg tataacgtat
     3661 tgattattga cgatgaggag ccattgcgcg aagccattcg tattatcggg gattgggacg
     3721 gtctgggcat cgaacatatt tatgaggcga cgaatggaag gttgggactg gagctgttgg
     3781 gtcagcacca tatagatgtg gtgatggtcg atatgaaaat gcctgagctg aacggtatcg
     3841 aatttcttcg tgccatcgaa aaggcatatc cccacctgct gacgattgtc attagtggct
     3901 acaatgactt tgaatttaca cggcaggcga ttcaatcccg ggtggtggac tatctgctca
     3961 aacctatcaa tcgtcaggat ctgaatcagg cactgcgcaa agccgtggac attctggaaa
     4021 gtcgagagca aagcaaaaac aagttcatta gccagaacat tacgctgaat atgtcactgc
     4081 cgaagctgaa agagaagcta tatttgtcca ttttggacgg tagcttcaaa aggcaggcca
     4141 atacggcgtt gctcccattg atcggagcgg atcagccggg gaatcgcttt ggggtgatcg
     4201 tgctgcggct gctgaacagg gatgagattc gcaggacacg ttttcatggc gatgccgatc
     4261 tgatggattt tgccgtgacc aatgtgttag ctcagacgtc agatgaacgg ttgagttgtt
     4321 ttagcttctc ccatccgcga cgggagcgtg aggtcgtttc gatctgtacc ttggccccag
     4381 gacaagaaga acatatggcc ttactattgg cacaagtgac acagaaggcg gtggcgaacc
     4441 tgcatgggct gttcagcatg gtggtagttg ccggattggg taagctctgc acagatgtat
     4501 tggagctagc gtctgcttat atggatgcca agacgctcat tcacagcacg gatgtgttga
     4561 agctggaagg ggaatccatt cttcatacag tgccacggca aatgggtacg ttagaggaaa
     4621 tgtcatggac ggagcgactg ttgtcgatcc aaaaggatgc tcagacaggt caggcgaacc
     4681 gggcaaaggt actgctgggc gatctgctga aacaattggc atcaggccct attttccgtt
     4741 tacaggatgc ggatcgaatg atgaaggagt tccatttttt actgagagaa gctgcgattg
     4801 agttgggtgc gtctacgtca gcgtcagcgt tgaatcaaga tggagctttg gaagaaccgg
     4861 agcaagtggg ggaaagcgat ttgtctgctg attttacgag ctttgtccac tacggtcaga
     4921 gattgaatcg gatgctggag ctttacattg ctggggtcca acatgctcaa gcggggaacc
     4981 agccctttga cataacggac atcaaaaggc acatcgaccg ttattatttt gaggatatca
     5041 aaatttcgtt ttttgccgaa acctatttct tgagtcggga atacctgatg aagctgttta
     5101 agcagcagtt tggttacggt attcacgaat atgtacagaa ggttagaatg gacaaggcga
     5161 aggagctgtt gggtgattct agcctgaaaa tacaggaaat ctcggatatg ctcggctaca
     5221 aagataaaaa ttatttcagt aaggcttttc gtaattatta tcaggtgtca ccgtctgagt
     5281 atcgcgtaag cctgcaataa accacttttt tacccttaac gcttcactaa tctgcctttt
     5341 taaattggag tatatttttt agaatgagcg catggacgtt gatcacaaac aaatggggga
     5401 gtatccatgt taaagaagat gatggcgtta tccggcagtt tgcttttgac ggtcggtttg
     5461 ttgagcggat gtggaagcaa cggcggcacg gatgcgtcga aagaaagtgc tggcggcaaa
     5521 gaagatttga aaacggttac aataaacatg ttcacagctt caccagagta taccgatgct
     5581 tttaacgcgt atatcgagga gtataagaag gtcaaaccta acgtgaagat caatctggag
     5641 atcatgcagg cagactacaa cacgattctg aagtcgaaaa tagcctcagg tagtacaccg
     5701 gatgtattcc aaacgacggc aggaggcgac atcgacacgt atgcggatta tagcgccgat
     5761 ctgaccaatg agccgctggc agcagccatg acggatgctg ttcgagcgaa tatgagctcc
     5821 agtgacggca aagtgctggg actcccggta aaagggaacc tgtttacgct gatttacaat
     5881 aaggatttgc ttaccaaggc tggggtaact tccccgccga agacgattgc agaaatgcag
     5941 gatgcggtca ccaagctaga ggcgaagggc attactccat ttgccaatgc atataaagag
     6001 tggtgggtat ggaagcatat cttccaacac tatgtagatg ctgccgcgca ggatgcaggc
     6061 gtggaaccga agcagctcgt tagtgatttt atcgcaggca aagcaaaaat caaggactac
     6121 ccagtgctgt acaacaactt ctttaacttc attgatttga cggtgaaaca tggcacagat
     6181 aagccactgg aacgggacag caatgcggaa gtaagtgatt ttgcatccgg aaaagctgcg
     6241 tttatgacgg gtaaaggtgc atgggatgag gaagcaatca agaaaattaa tcctgatctc
     6301 aagattggca tcatgggata tccggtgagt gacaaagctg atcaatcagt cattattact
     6361 ggtgcagatc aggcgctgcg tatcaataag gattccgaag tatcgaagga aacaattgaa
     6421 tttttcaact ggctgtacac ttcggaatac ggtaagaact ggttctccca ggtagcgaag
     6481 gtgattcctc caattaagga tgcaccgctt cctgatctgg aaatgcctaa ggaaatggaa
     6541 agtattttga aaacgtcgaa gtccggtgat ctgtctgtta actactcgct ggatacgttc
     6601 caccaaaaat ttggtgagct gatgcaggca tatatcagcg gtaacatgaa caaggatcag
     6661 gcggttgcag agattgagaa ggcatgggta caattaggtt cagcacaata agattggtat
     6721 tgcagaggcg tccgtaaggg cgtctttttg tattatagct aggaggcgga gaggggaagg
     6781 acaaaaaaat atttaataat ttttaaatat ttacttgcaa aaagttattg ggttgtggat
     6841 aataggttgt gtgcaatata tctacaacat acgacataca taatgactgc aagttgcaaa
     6901 tgtgagagat cccccgttgg aggaatctct tttattccgt ttggactatg ccgattatgt
     6961 ttttaataga ccgtgtaatt tggagcgtat ttttcgttta tgtgacgaag ataaaaagga
     7021 gatgaacgtt ttgacgaatt cgttgtttac accgtataca ctgaaagatt tggaattaaa
     7081 gaatcgtgtg gtgatgcccc cgatgtgcca atactcggtg acagccaagg acgggattcc
     7141 gaatgattgg catcatgttc attatttgag tcgggctatt ggaggtacgg gcctgattat
     7201 tatagaaatg acggacgtgg aaccggatgg acggattaca gattatgatc tgggtctttg
     7261 gtcagacgag catatcccag cttataagaa gctggttgac ggcattcatg cgcacgggtc
     7321 caaggtaggc atccagattg ctcacgcggg ccgtaaagct gaggatgcag ctgagccagt
     7381 ggctccttcc gcgattgcat acccggatgc gaattataaa cagccacgcg cgcttacgac
     7441 ggaggaagtc cgtggcatgg tgcaaaaatt cgcagacgct acccggcgtg cagttcaagc
     7501 gggcgtggat acgattgaac ttcacggggc acatggttac ttgattcacc aattccattc
     7561 gccagttaca aacaagcggg acgacgagta cggtaaggat ttatcccgtt tcggcgttga
     7621 ggttattcag gctgtacgca agcaaatgtc tgcgggtatg ccgttaatct tacgcatcag
     7681 tgcggtggaa tacgtagatg gtgggtacga tgtggatcat gccattgagc tgagccgtgc
     7741 atatcaggct gcaggcgtag acgtgatcca tgttagctcg ggcggggaag gccctgctgg
     7801 cgccagaaag ccgggcaact atccgggcta tcaagtgccg ttcgcacgcc aaattcgcga
     7861 ggcactgaac atcccggtga ttgctgtagg ctcgttggat gacccagcct tggcgcagtc
     7921 cattatcggc aacgaggatg ccgatctggt cgctgtggga cgcggattgc tgcgcgatcc
     7981 atattgggcg attcatgcag cagtgacgct gcgcggcgag gagccttcca tacctgaaca
     8041 atatcaacgt ggctactgag gcctaagtaa tcccacgttg tttatatata aacaaggcac
     8101 ctgcaacgaa gtgtacgctt cgtcaggtgc ctgttttgtt ttatgggttg tctttatttg
     8161 taggatggct cctgcacttc attttgcaga aaatcttttt gtttcctata agagttagaa
     8221 taagtgctgc tataagacat tagatccgca tggctacctt gttctacaat tcgaccattt
     8281 tgaacaacta atatatggtc cgcatgaatg actgtttgga atttatgagc gataatgatg
     8341 atagttcgtt tacctttaag ctcatttaaa aggtgcagaa ttagagattc agtttcagcg
     8401 tcaagggcag aggtcagctc atccaaaatg agcacagggg cattgtgaag caatgccctt
     8461 gctatagcca gacgttgttt ttggcctacc gataagtcat attttccaga aatgatatta
     8521 gtgttatatt tttcgggaag ggatgagata tagtcatgta accccacctt ctttgaaata
     8581 ttaacaactt catctaaggt agcattttta ttgccaaagg caatattatc gaatatggtt
     8641 cctgttgtta ataattcttc ttgtgtgact accgctatat ttttatagaa gtaattttta
     8701 ttcaaatcgt gtaatctgtt atccccatag tagatctcgc ccttagtcgg aatgacttct
     8761 ccggttagga gcttcacaat agtcgtttta ccagatccac tttctcctac gatacctaac
     8821 atttgatttt ttttgatttc aaacgagatg tcatcaagaa caggagtaag attgttatag
     8881 gaaaaaaata cattttttac gtatattcca tttcccgtaa atccttcaat atttgtgccg
     8941 ttccaaacat catttaaatt gaaaaagtta agaatccttt cagctgaagc taccgctgat
     9001 tgcacaccta catttaattg tgacaagcgt gataccggtt gtagcaactt gactatatat
     9061 gtactgaaag caaccagtgt acctaaggta atctctctat caattagcaa aaaacctcca
     9121 atagctagta aaagtaaagg gaaaaatcca cttaaaaagt tactgattat acctagtagc
     9181 agttctcgcg caaaaagttt tttcaaaata cgaaccaaaa gtatttgttc tctgcaaaat
     9241 agggcactac tatatttttg acggttgaat ctgattgcag tccatttttg tttcaaacct
     9301 aactgaaggg tttctgtcat attttcatat tgttttttgt aggcaacatt taattggtac
     9361 actttctttt tggaattgta gtataagaaa aagtaaatag gaataaagat cagggagacc
     9421 gttgccagct tccaattcat aaaatagaga acaacaacgg ttgcgacaat tgtcagacag
     9481 tccgtaaaca tagctataaa tgcttgattt agcaatccag taagagcttc gacatcatta
     9541 taaagtaagg aaataatttt tccagtgggc tggtggcttc gtaaatttag attttgttga
     9601 tatatatcat tcctcaaccg gaactgtaat aaatttttga ttttaaaaat aactgaatct
     9661 ctcagtgctc ctgtgaatcc tccaccaact agtagtaata aaaaaaggct acctaaatag
     9721 ctgatttctt tagctgagag tgtttctgtg ttataggaat ctatcagccg ttgcattaaa
     9781 ataggttggt agatcatgaa caatatattt attataatga tacaaagtac agtaatttgt
     9841 agtgccagta aaggcttaat gtattttctg attagttgga acataaaata ggccctccat
     9901 atttagggat aaagccagat aagatagaat cagagtagct agatcggcat tgttaataaa
     9961 tgatatgaag tcttagaggc acaatgccga gtagttatta ctaaccaaaa aggatgcttc
    10021 tttgttcctg ggtaagttgg aggtataatt ttatagtagc gttaatgaaa ttcttagtta
    10081 ctttgcaaag tttaccgaca ggttgattga catttccgtt ctccgcgaag ttctcttgat
    10141 ggcatccacc accacaaaga tttttggccc aacactttga acaggtggtt ctatttctta
    10201 ctgttgaatt ctcaatgaaa ttatactgtt tgctcaatgg atcttcatca aatagattgc
    10261 caatagagca ttcatcctcg cctacaaaac gatggcaagg gaacaaattt cccctaacat
    10321 caacagcggc cgcattcgta cccgctccac aaaagtggat tctaggaccg ccggaatgaa
    10381 ttttactaag catgccaagg acattggaca tttttttggc tgtaacatag tcttcacgtt
    10441 ccagtaactc tcggaattgc tctacgagtt taaccatttc tttcgataaa gtatcgtaat
    10501 gctcgtccga tagggaataa agtgctggag ataaatatat ttttctgaac cccagtttca
    10561 ctaaatgatc aaaagattta gaaaggtcaa gctctgcagg agttactgta ccgcgcgcgc
    10621 ctattttacg atcatttctc atttcttctg tacgcttcaa gagtaaatcg taggatcctt
    10681 gtccaccttt aaaaaaacga ttgaagttat gcgttttttc atcaccatct atgctggtct
    10741 gcaccgcaaa atgatgtttg taaaaaaagt ttttgatttt aggagtgata agtgtaccat
    10801 ttgtagttat tgaaaaagaa aatttcttat tatgaatttc ggattgctca tgaacatact
    10861 gcaccgtctc ttgtatgaga gggaaattta acaagggttc accgccgaaa aaagtgatat
    10921 tcaattgctc tatttcaccc gattgttgga tcagaaagtc tacggcagat ctagcaatct
    10981 ctgaagtcat tttccctttt tgattatatt ccccttcctc tccataacag taagtacatc
    11041 taaggttaca ttcttgcacc ataaataagg tcagagagga taatttgaag actctttgcg
    11101 agttatcaag tatacccatt ttttcaacat ctgatatgtt agtatctgtg gcaataatgt
    11161 atgcttcctt catattttgg atggcttctc ttacttgtga taattcataa cgctcggcta
    11221 aatccttaac aacgtgctcc tcggttttgc ctttactatg tagaatatcg ataattaatg
    11281 agtcaatctc aaatatggca ttcgttacga cgttataaaa gaaggttttt gagtcgactt
    11341 caaacaattt ataagggtga aaatgaatga tttcatcttt tttatcctgg atcagattag
    11401 ccatttcaaa gacctcactt ttattattaa gataatttaa gaagggggaa acgggattaa
    11461 gtaaaattaa tcccgttatt tagatataga taaatactag gtatcactag aaatacagaa
    11521 atccattgca tcacatgaac ggcagtaatc tttgagatcg caataatagc aatcatcatt
    11581 tttaggacat ccgtacgcaa gaatgggttc tttaacacca gagataacgt tgatttgttt
    11641 cagcataatt ttcacctcct ttcattttga tgatacgaat ttctaagtat cgctagttac
    11701 acaaaaatca gattgatcac atattccaca gtagtcacga gtatcacaaa aagtacaata
    11761 atcgacttct ctacaaccat aagagcgaat tggttcttta atcccagcaa taacgttaat
    11821 ttgttttatc atatattttc acctcttttc attatgctac acggtgcatg gacatgtaag
    11881 gtatgtagaa atcatacacc caaaaaggaa aaatatgtgt tacaaaattt tgtataatat
    11941 tattactttt tgtattattt catttgagtt tatgaaactt atatcacatc ttttactagt
    12001 tttaagatgt aaaatgaatt ttttgttatg tatgtaacta aacattgaat aatactataa
    12061 ttgtaatttt aattgattca ttacaataat aaatgtatga taaatggtga ttattgtaat
    12121 gggaggttta gaaatggatt atattatcga aacgaaaaag ctccgcaaac agtttggggg
    12181 ggctgtagct gtagacgaca tatccttaca tgtggagcgt ggcagtatct acggtttcct
    12241 cggtgaaaat ggagcgggta agacaaccac tatccgcatg ctaatgaggc taattgagcc
    12301 tacaagtggg gaggtttttt tatttggcga gcggctggag aaaaactatc cttctatttt
    12361 ctcgaaaata ggtacaatta tcgaaacgcc tggtttatat gaaaatttga gcgcacgcga
    12421 caatctaaga atttgctgta tgtacatggg ggtgcaggat gatgggagaa ttgaacgaac
    12481 attaactact gtgggattag agcataccgg caaaaaaaag ttcaagaatt tttccctagg
    12541 aatgaagcaa agattaggga ttgcaagggc gcttgttcat gaccctgagt tgcttatatt
    12601 agatgagccg acgaacggac tggacccatc tggaattaag gaaattcgtc agctattgaa
    12661 gcggttgtgc gaggaagaag gaaaaacgat tcttatttcc agccacatct tgagcgaaat
    12721 tcagcagtta gctacacaca tcgggattat acataatgga aaactgttag cggaagatcg
    12781 tttgagccga ttagaggaag gttttgagca atatacagat gtaaaggtag acgatgcaga
    12841 agcagtgcaa gcatttctgc aagagcacat gaagcaactt caatctaatg tgatatcccc
    12901 acaacaacta agaattcata gtcagattga gaatacagct gcgttaaata agcagttaat
    12961 agatcatcag ttttcagtct atgagataca cacctccaag cagacactcg aggagtactt
    13021 tctgactctc atttcaggag aggatgggcg acgtgattag agcagaactt attaaactta
    13081 aaggctctaa agccttcttg ttgagctata ttatattgct ggctgttgtg ctgttggaat
    13141 ttgcgacgag cgctattttt tacagatatt caattgataa acggggttgg acttactatt
    13201 tcgagggcat agttctcttc gtcaatgttg cagccggatt tatcagttac tacatattaa
    13261 ccggtcatat ttttgcaaga gagtatcagg aaaacacgca tctatttatg tttaccacgc
    13321 ctgtcaccag ggttaaattt tattttagta aattgatcat tatttatgga tttattattg
    13381 tatccttatt tctcgttctg tttttgtctg ccttattagg catgtccatt acagatcgac
    13441 ctttaacgat ggctatctgg gtataccaaa tccaagtgtt tgctaaaatg tgtgtgatgc
    13501 atgcgatgtt aatcccaatc gcctcttttt ttgctatacg ctggaagagc atcatggtgg
    13561 ttgtactcgt agtttgtact gcaatatttt tgaattttat atacaaaagt gaatggtatc
    13621 cgtggattgt tccgtatctt ttatctccta atgaaagaaa tgcgactata cctaccaatg
    13681 tttcagtagc atggttcagc ttatcggtga cctttcttct tggattgctt ttatctatat
    13741 ggacatatca aagaaaagaa taaatagaga gttttcgaga ggagggttac tatgcttgac
    13801 ctgtttaaag cagagtgctt gaagctgaaa ggaactaaaa ttgtttggtt gagtgtaatg
    13861 attttagtat taaccattgt tttagaattt tatagttacg cggatagtcc caagtattcc
    13921 atagatcgtg atggttggaa tgactacttt atgagtgttg ttattcttat taattttctg
    13981 actgggtata tgagctacta tattttgacc tgctatatct atgcgagaga gtatcaggag
    14041 aagacccata ttgcactgtt tacaaacccg attcgccgga ctcgtattta cttcagcaaa
    14101 ctactcgtta tttatatgta catcgctgtt agcctactga tggcatttgt gctatctaca
    14161 gtattgggta cgtttattac gaccagaccg ctaacctttg aaattgttat gtatcagctt
    14221 ggggtatttg ctaagatgat tcttatgcac gctatgctta tcccgatcat cacgttcttc
    14281 gccatccgtt ggaaaaaatt tgtgcctgct attatgggaa tgtgtacggt catgtgttta
    14341 aattttgttt tggtaaatac accggggaat accttttatc catggacagt gccgttattg
    14401 ttttctcccc atggacaaat gggcagaaca ttcacgtatg ttcctggagg ggtcatcagt
    14461 attttcttta tatttgtgct gggacttttt ttagcgttgc gaagttatgt tcgtatagaa
    14521 aaataagtag agtataacaa aaagaaatag accgccctgg agagggaaac acggtctatt
    14581 tctaatagct agcccttttc agccgaccgc tcttccaagc ggctgttgcc aagagtaggg
    14641 atggttacca gcatccttgc tcttttttcg gtatatcctt ctatttttta ctttagcaca
    14701 attggataat cattgtaact gaatgtgacc gttacttggt gaaaacttta acttcctttg
    14761 gagcgagagt cacggtgatc gaaccgttgt taatctgaat ggagtcgttg ctcagctggt
    14821 tggtcagacg ggtaccgttg gacagattgt cgaagttgcc aatcgtgcga gtttgactgc
    14881 tccatgagtt gttgataagt acgatggcct cgtcgccatt tttagagcgc tggaagctgt
    14941 aaaaggagtc gtccacccat ttttcctttt ggttgccgtt ttgcagagca gggtggttgt
    15001 tgcgcacaga gttcagctta gcgatgtact gatacaggtc atggttggcg ttgaaattca
    15061 tattctcccg gttggcagga tcttccccgc cattaaagcc ttgctcagtg ccttggtaga
    15121 tgattggaat tccgcgtgac gtcagagtaa agcccaaagc agttttgagc tgtggccatt
    15181 tgtcatagtt agcacccggc ttgccggagg cgtcattcag gaaacgtttt acatcatgat
    15241 tgtcgataaa tacaccgttg gtctgggcat cgcgatagta acgatcatct gagtagcgct
    15301 ccttgatttt tctcatggat tgatcgtgtc cgaacacatc cttgattgta taatacatcg
    15361 gaaaatctaa tgcggcatcg agatatcggg tgtaatcccc cacataagca gggtcgccat
    15421 ggaaaatttc acccatggtg aaggtattgg cggcttggtc aaaatccttc agaaaccctt
    15481 tgggtacatg cttcacagtg tccacccgca gtccgtcgac ccccgactcg ttcaacagcc
    15541 atttgatcca gtttttgagc tcatttgctg ttgcagggtt gtcctgattc aggtcatcta
    15601 atccagccac atcaccgttt tcgattttcg attggttgtt ggagctgtag tctgctcctg
    15661 tgatgtcgcc attgtgatga taccaatctg ctttgtcaaa gggagccttg gcgatgccgt
    15721 tcccaggttg aaaatcgccg gtgtgattgg gaactacgtc cagcataaca gcgatatttt
    15781 tgtcgtgtgc cttaccaacc agctctttga acttgtccat ggtaccgaga tgtccgtcta
    15841 ccgcataaaa atcatacgta tgatagccgt ggtaagcgta ttcactcttt tgcatcgtta
    15901 ccggggtaat ccagatcgcg gtaaacccca tatttttaat gtagtcgagt tggttaataa
    15961 taccttgaaa atcgccacca tgccacttgc gctgatcgct gttgttggaa ttgaaaccac
    16021 cgtaattatc gttggatgga tctccgttgc tgaatcggtc tgtcatgata aaataaatgc
    16081 tctgtttgct ccagtctgtg ttgagggaag tgggtttgga gagggtattc agatctatag
    16141 gagtgaaggc gctcgaaggc gcctccgttt gaatagttac ttcaactccg ttagagttgg
    16201 gtacgtacgt agaagtgcct acatttaagg atgcacccga aagttccact gtttggatag
    16261 gtcctgtaac ttcgttgagg tcggttgcgt aggtggaagt ccctacgctg acggcacttc
    16321 ctgaaggtgt ccccgttcgg atagatcctg cagctccgtt caagccgggt gtgtaggtag
    16381 aaattcccgt gctgaaaagg tagtttttgg tgttgttgct gtcccagctg ttattgccgt
    16441 cgttaaaagc ggcttccaat tgggaggcag acccgatatc gacggtaatt ttggcatagc
    16501 cgctaatttc ggcatcctgc attttcacac caggcgcagc agtccagctt ccgccggcag
    16561 ggcgatagtg aatgtaaggc gaattaaagc cttttttgta gtataccgtt accttgttag
    16621 ttgtaccgcc gccatccccg ggaatcgtac ccgctggagc gccagatgtg atcgttcccg
    16681 cattgccgct gttaccgggc gtgtacgtag aagtgcccgt actgaaggag tagtttttgg
    16741 tgttgttgct gtcccagccg ttattgccgt cgttaaaagc ggcttccaat tgggaggcag
    16801 acccgatatc gacggtaatt ttggcatagc cgctaannnn nnnnnnnnnn nnnnnnnnnn
    16861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16921 nnnnnnnnnn nnnnnntttc ggcatcctgc attttcacac ccggtgcagc agtccagcta
    16981 ccaccagacg gacggtagtg aatgtaaggc gagttgaagc cttttttata gtatatcgtt
    17041 actttgttgc ctgtaccgcc attattgtca ggcttggctt tgctgatgat atattgtttg
    17101 aatccactca actcaccggt tggtgagcca tcattgttga cgagattatt gatgcgcaat
    17161 aacgtaaacc cgtgataacc gaacttcgtg attttctcct cgattttttg gaagccgctg
    17221 ccgcctgtcg ggagtgcatt ttcaccattc aggcgaacac ccttggcatt cgcgatggag
    17281 gagacggtat caaccagggt ggacggcaac gaataattcg gtgctgtgcc actgtcactc
    17341 atctccaggc aagtaaatgt caaatccaga tccgcatctt tgaacttctc gatgagacgg
    17401 ttgtaatcat aatacccacc tgcttgctct gtgctgtgag gcatggcagg attgttcatc
    17461 tgccagtgca gaccggaaat cttggctccg atacggacac cgaacacaga atcgaagttt
    17521 ttgtgtgcag cagctccgat gacgcccaga tgcttctcaa gcacgctttg ataccacgac
    17581 agaaaatcct ttccatacgt ggaattatac ccgccgttcg tataaaatcc gtccccgtca
    17641 gtcggcggat tgatttggct aaggctgctc agcttggtac cccatgccgc attaatctta
    17701 tccattgatc catacttttc attcatggcc gtgcggaacg cacttttggc tgtttcagtg
    17761 taggcttgga atttgccccg tgcaggataa ctccatcccg ctgccggata gtatgaagga
    17821 tatcgcaatt ctccagaggg cccaccgctt aaataaattt tgggaatgat gcttttgtag
    17881 ctagcaaagg tttgagcaaa tgaggcatat agctcgtcat attgtttacc agtcccgctc
    17941 cataatggag agagggcttc gttattggca aaaccgcttt cgtccttgaa ctgcatttca
    18001 tctgcactgc ccttgctcga cagccagctt ggcagtggga tgttgcagtc atctcccaca
    18061 tttcctccac acttatgcgt tgagatgata ggaacccact tcagtcccgc ttctttcacg
    18121 gcatctgcat aggtcttgta gtagctccaa tcgaactggt tatctcctgc gctctccaca
    18181 tagccccacc agacgtcggt agtgatggca tacacgccat tgtttttcaa cgtttgcagt
    18241 tgctttttaa aggaacccca gtcattaatt ttcgccagcg gtcccataac ggaagcctga
    18301 aaatcatctg caaccgcagc gctcgccgta ttagagggtg agccaatgaa ggcggtcaga
    18361 gacagcacaa ggcttagtag aagcatacac ccttttttcc atagacttcg atacaaggtc
    18421 aaaccgatca tcctccccaa agcatagtct aattcgacaa cattttgtaa acgtctacaa
    18481 aaatagtata aagcaagcgg ttgcataaaa agaagaattt attgcacact cagagtggac
    18541 aaatatgaca ttttacgtaa gcaactgtgt gcttaaaagt ttccaggcaa aaaaataagg
    18601 cataggtctg agtaagacgc atgcctttta atgatgtgcg gatagacaat gccagtatag
    18661 gagaaagcga acctaggcgt agagaagcct tgttccagtc tgtatgaaag tattgccgag
    18721 acagcttgct taataaatag ggcgattctt ctggtccgga atgccacttt tacggtagaa
    18781 atacgtattg atccgatccc gccattcttt ggcatgctca gtctgatgct ccagccgctc
    18841 cagcacctgt tcatacatgg catcattcaa ttgccctcgt agactaaccc atgtgtctcg
    18901 gagatgggcc gcacgttctg caccttcaaa atgggtatca taaatgtgct gtatgacagt
    18961 ttgaccggag tggagcaagt gtgtataagg aacatggtga aagaataaaa gcagctcatc
    19021 cgggcaggtg tccatagatt cgtagatatt agtattggga gaaaaatatt gtcctgcata
    19081 gcccgttccg gttgcggacg tgcgatctac cccgatcccc cggcaatcag caaaatggta
    19141 ggtgccccac atagaatatt cgtacccgtc tacatccggc ccatagtggt gatcgggact
    19201 gaccatccag ccgaccccga gaggggcggt gtaggattcg tagatattcc atgaattgag
    19261 cagcatttgc ttaacggtag aaattaaatc tgtgtcgccg tcgctattcc cttgtctgcc
    19321 aaacgtcagc cgaacccact cgtcagcgat ttcgtctgcg gacaggtccg ggtcccatgc
    19381 caaccggcca tagccataaa gattggactg ggcgagcaaa tgtccggtcc aattggtgtc
    19441 tgcaccaata ttggatacag cggctattcc atagttggta tgcttgggag aatgcagagc
    19501 gccactcacg atacgcttga tggtgaagcc ttttccttgg gcgtaggtgt caaaatccaa
    19561 tacttccttc cattggggaa caagataaca tagatgtttc tgttggccgg tgtactcttg
    19621 cgcaatttga aattccagca gtacctgagt ggattccagc gcaccgaaca ggggggagac
    19681 aggctcccgc acctgaaaat ccatgggacc atttttgatc tgtaaaatga cattttctcg
    19741 aaacagtcca tccagcggtt taaaatggtc aaaggctgcg cgggcccgat ccgtcttgcg
    19801 atcgcgccag tcctgcttgc agttgtagac aaagcagcgc caaatcacac gtccgccata
    19861 ggactgcaac gcatctgcca gcatattggc tccatcggcg tgatggcgcc cgtagctgaa
    19921 cggtccgggc cgattttcgg aatcggcttt gaccacaaaa ccacccagat cgggaacggc
    19981 ggcgtaaact tcctgggctt tggtctgcca ccattcagct acagctgatt ctaagggatc
    20041 ggccgtggtt aacccgccga gctgaatagg actggcatag ttaatgctca agtagatctg
    20101 tatgccatag gcgcgaaaca ccgcagctac tttagccaca tccggtagga atttagctgt
    20161 aatcagctcg gtctctacca gatggacatt cacattgttg atggatagcg cttgaatgcc
    20221 tacagaagcg agcagacggg catagtctcg caggcgctcc atatttgtag taaaggcatt
    20281 attatcgtag aaaatagatc cgcccgcata tccacgttca acactaccat ccatgttatc
    20341 ccagtggttg atcatgcgga tgggattaac agggttggat aattggtcta gaatgggggc
    20401 gtgcaatgat tcggtggtgg gcttcaactt cccatctagt cctccttgca ggtagcgtag
    20461 cagatgaaag actccgtaca atacgccttt ggaggtctgc cctgcgactg taacatattg
    20521 tcctttgaac tcatcgttac catgcgaagc tgaatatgcc ggatctggca tctctatccc
    20581 gcgaattcgg tagccttctg cgcccacttc tgcctgttcc gctgcgctga atcgttctgc
    20641 gaccaaagga tgcgctggga acgtacccag cgcaatgaac ggcgcattca caggaacggc
    20701 gctgatcttc ggctgctgtc caaacatgga ggtcaatcca tgctgaagct cactcgcagc
    20761 cgattgaagc acttcatctg tctcatggac cacgatgacc ctgcaccaag cgggcagctt
    20821 ttctacctta ctattgcggc tgtaatgcag ccaagccgca tagccgctct cttttggcat
    20881 atccataatc ttgctcatat tggagcctcc ttttgagcag gtgaagattg tcctcagaca
    20941 tgctgttcct gatcccgact catatgctca gggagagtca gacggttgcc gttgccttca
    21001 tacagccaca aaatagcggt cactccgcgc ggataatatt tactgccgtg ggcaatgccg
    21061 gagagtatct gatcgctcca gcaccaatag gattcttcag ggtgaaggag ccatgagacg
    21121 tgggcagcgt ctgcggcttg cccagcttct tcccaaggca gctccagcag ctcgcgggca
    21181 ataaactgcg acagatagat tttgctcagc caggagttgt tactggtcga ggacagcttc
    21241 cagcctccgt cttcaaacag acaaactccc ggtaccagta cagtttccaa atgacgccgc
    21301 aatgcttgga tatatccacc gaaccgtcca tcaggcttaa gcgcatcctc acatcctgta
    21361 aagtaaggga agatcagtcc ctcaatggca ggaataatct gcga
//
