LOCUS       NZ_JAMXJO010000001     20744 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Nocardiopsis dassonvillei strain RACA_4 assembly, whole genome
            shotgun sequence.
ACCESSION   NZ_JAMXJO010000001
VERSION     NZ_JAMXJO010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardiopsis dassonvillei
  ORGANISM  Nocardiopsis dassonvillei
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Nocardiopsaceae; Nocardiopsis.
REFERENCE   1  (bases 1 to 6726007)
  AUTHORS   Elfeky,H.H., Hanora,A. and Solyman,S.M.
  TITLE     Bioactivity of bacteria associated with Red Sea nudibranchs and
            whole genome sequence of Nocardiopsis dassonvillei RACA-4
  JOURNAL   Mar Genomics 67, 101004 (2023)
   PUBMED   36521348
REFERENCE   2  (bases 1 to 6726007)
  AUTHORS   Elfeky,H., Hanora,A.S. and Solyman,S.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2022) Microbiology, Suez Canal University, 4 Km
            Circular Road, Ismailia 41511, Egypt
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Assembly Name                     :: SCU_Nocdas_4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: GCA_900638215.1
            Genome Coverage                   :: 7.6x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024181525.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 06:43:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,838
            CDSs (total)                      :: 5,775
            Genes (coding)                    :: 5,721
            CDSs (with protein)               :: 5,721
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 7 of 54
            Pseudo Genes (incomplete)         :: 51 of 54
            Pseudo Genes (internal stop)      :: 0 of 54
            Pseudo Genes (multiple problems)  :: 4 of 54
            CRISPR Arrays                     :: 12
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:23:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6394575
            Orig. end                         :: 6415319
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAMXJO010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20744
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="21"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20744
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20744
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10744](+)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10744
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            465..848
                     /locus_tag="NGM33_RS27140"
                     /old_locus_tag="NGM33_27140"
     CDS             465..848
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013152185.1"
                     /locus_tag="NGM33_RS27140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27140"
                     /product="hypothetical protein"
                     /protein_id="WP_253797262.1"
                     /transl_table=11
                     /translation="MNVTDVLTYAGAAFLNGICVVSAVDVLLRIRDRGRFRFADRWDVL
                     NRTAHTLFFLVLSLLLTTWASFPVAVWYLDVALSAGAAAVAVLCWPGLPARAADAGAAS
                     RRHSAVGTLVFLAVVLAVFLLFA"
     gene            1118..>2451
                     /locus_tag="NGM33_RS27145"
                     /old_locus_tag="NGM33_27145"
     CDS             1118..>2451
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013152186.1"
                     /locus_tag="NGM33_RS27145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27145"
                     /product="ATP-binding protein"
                     /protein_id="WP_253797264.1"
                     /transl_table=11
                     /translation="MPFHPSDRQRRPPRPGRQALAALFAVTALAVPAWSWAVATAHPDA
                     RQSVALAVGAAGAALCAAVTSAAHQAAAARAARERGTRVDATAQALEREAEHLVDQLLP
                     ALTEGLRAGRTAREVLAEHPQPRHVALHRLTHAVTAELDTARVRAADALARRTALEEQI
                     ADLDRVGLPLMVARVREDRVGAAEALREELPPVHDTLARLRAHTLEELLAAARRSASAM
                     ETAAASGARIQAHLTSLLARLRELQDRYGDSPGVFGDLLDIDHGVSRTGRLADGLVVLA
                     GGRSGRRWTRPIAMESILRGAMGRISAYRRVRLHNTSTASIAGHAAEGVMQALAELMDN
                     AANFSAHGTEVHVYVQEEDTGLSVTVEDSGLGMRVRERRLAESLVTEPRDLSTLRGTRT
                     GLAVVGRLAHKHALGVSFRPSARGGVGVVVLVPPHLVTESQPAPGG"
     misc_feature    1119..1129
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     assembly_gap    2452..2551
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="clone contig"
     gene            <2552..2803
                     /locus_tag="NGM33_RS27150"
                     /old_locus_tag="NGM33_27150"
                     /pseudo=""
     CDS             <2552..2803
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017588960.1"
                     /locus_tag="NGM33_RS27150"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27150"
                     /product="sensor histidine kinase"
                     /pseudo=""
                     /transl_table=11
                     /translation="VLAARVCAARPDAAPAAARAPAPAPARAASGLPRRRRGQTLAAAL
                     REEPDQLSAGPATPGPGGDPGTRFASFRNARQPQRAEE"
     gene            2864..3289
                     /locus_tag="NGM33_RS27155"
                     /old_locus_tag="NGM33_27155"
     CDS             2864..3289
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013152187.1"
                     /locus_tag="NGM33_RS27155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27155"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_130397237.1"
                     /transl_table=11
                     /translation="MNTMDTSLDWLLENLRHGTPGIRHVLVLSRDGLRMCHTRELHTDR
                     ADQLAAIAAGIQSLSLSASAEFGDRGGAGQAMVEFGGGVLLIIRAGEGAHLAVVAAGEA
                     DVGVIGHSMNALVGRIGGFLTAAPRRSERLRVGAEQR"
     gene            3286..3648
                     /locus_tag="NGM33_RS27160"
                     /old_locus_tag="NGM33_27160"
     CDS             3286..3648
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610354.1"
                     /locus_tag="NGM33_RS27160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27160"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_130397238.1"
                     /transl_table=11
                     /translation="MTHHDSLRAEAPDRLYTVTGGRSDADTRVFDSVTLVVAECDPVPG
                     MQSEHAAILRLCAYPTAVVELSAELRLPVSVVRILLLDLLDTGRVSARHPAALTRQEAG
                     HDPETLKQVLLALQRL"
     gene            3629..4339
                     /locus_tag="NGM33_RS27165"
                     /old_locus_tag="NGM33_27165"
     CDS             3629..4339
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610353.1"
                     /locus_tag="NGM33_RS27165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27165"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_253797265.1"
                     /transl_table=11
                     /translation="MPSNASERLAGPRRAPLAATADNALKIVVVGGFGVGKTTLVDSVS
                     ETRPVSTEEVMTQASAGIDDLSAVRDKRTTTVAFDFGRITVDERRVLYLFGAPGQKRFW
                     FLWNQLFEGSLGAVVLVDTDRIRDSWYAVDRLEHHRTPFVVAVNRFGPGPALPEVRRAL
                     DLSERVPVVDCDARSRESSRDVLITLVQHVSGPVAGYPSAPPTEFAPGSGQASAPAPTS
                     GPASVPAPTQEETT"
     gene            4336..5601
                     /locus_tag="NGM33_RS27170"
                     /old_locus_tag="NGM33_27170"
     CDS             4336..5601
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013152190.1"
                     /locus_tag="NGM33_RS27170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27170"
                     /product="cytochrome P450"
                     /protein_id="WP_253797266.1"
                     /transl_table=11
                     /translation="MNHSPGPEAAAPASSGPPPPSPDHAGAARLYGPDVARDPAGLYEE
                     LRGRYGPVAPVLLDGDVPAWFVMGYRELHHVTSRPEWFARDCRRWNQWDRVGRDWPLMP
                     YVMWTPSVMFAEGAEHQRRAGAIGDALDAVDRTDLRALCQRAADGLVDAFRAEGEADLV
                     SQYAHRIPAMVVARLYGLPEAEVPALVRDVVLSLDATADAGGAHQRLRARLDALAADRR
                     AAPRDDVPSRLLLHPAGLSDAEAAIDLLVVLAAAQAPTGNWIGNTLLLMLTDDQFSLTL
                     QGGRGSAGEALNEVLWKNTPTQNFIGRWAVQACELGGRGIRRGDMLVLGLSAANADPRL
                     HAGLPDGHGGNRAQMSFGHGEHGCPFPAPEIAETIARTAVESLLDRLPDVRLGVPPERL
                     EWRPSLWMRGLFELPARFTPQR"
     gene            complement(5799..6755)
                     /locus_tag="NGM33_RS27175"
                     /old_locus_tag="NGM33_27175"
     CDS             complement(5799..6755)
                     /NRPS_PKS="Domain: PKS_KR (32-113). E-value: 1.5e-06.
                     Score: 20.1. Matches aSDomain:
                     nrpspksdomains_NGM33_RS27175_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610351.1"
                     /locus_tag="NGM33_RS27175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27175"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_253797268.1"
                     /transl_table=11
                     /translation="MTTPQRRIGSGFGRRSTAREVLDGIDLTGRLAVVTGGYSGIGLET
                     TRALAGAGARVVVPARRPQAAAEALAGIGGVEVDGLELSDQDDVRAFAERFLRTGRAID
                     VLVNNAGVMACPRAAAGPGWEYQFATNHLGHFTLVNRLWPALAEGGARVVSVSSGAHQA
                     SPIRWEDPWFARGYDRWLAYGQSKTANALFALHLDRLGEPLGVRAFSLHPGAILTPLQR
                     HMTRREMVDAGWVDGNGELIDPRFKTPEQGAATQVWAATSPRLAGMGGVYCEDCDVAVP
                     AGTEPGVEGVRDHAADPAQAERLWAFSAELTGENALA"
     CDS_motif       complement(6210..6320)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NGM33_RS27175_0002"
                     /evalue="2.80E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="NGM33_RS27175"
                     /protein_end="182"
                     /protein_start="145"
                     /score="-2.4"
                     /tool="antismash"
                     /translation="LAEGGARVVSVSSGAHQASPIRWEDPWFARGYDRWLA"
     aSDomain        complement(6417..6659)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NGM33_RS27175_PKS_KR.1"
                     /evalue="1.50E-06"
                     /label="NGM33_RS27175_PKS_KR.1"
                     /locus_tag="NGM33_RS27175"
                     /protein_end="113"
                     /protein_start="32"
                     /score="20.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVTGGYSGIGLETTRALAGAGARVVVPARRPQAAAEALAGIGGVE
                     VDGLELSDQDDVRAFAERFLRTGRAIDVLVNNAGVM"
     CDS_motif       complement(6582..6659)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NGM33_RS27175_0001"
                     /evalue="1.30E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="NGM33_RS27175"
                     /protein_end="58"
                     /protein_start="32"
                     /score="21.0"
                     /tool="antismash"
                     /translation="VVTGGYSGIGLETTRALAGAGARVVV"
     gene            6949..7920
                     /locus_tag="NGM33_RS27180"
                     /old_locus_tag="NGM33_27180"
     CDS             6949..7920
                     /NRPS_PKS="Domain: Abhydrolase_1 (23-305). E-value:
                     1.6e-33. Score: 108.3. Matches aSDomain:
                     nrpspksdomains_NGM33_RS27180_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610350.1"
                     /locus_tag="NGM33_RS27180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27180"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_253797269.1"
                     /sec_met_domain="PF00561 (E-value: 1.1e-28, bitscore: 99.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7.6e-18, bitscore:
                     64.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVEHRDVEVNGIRLHVAEQGGGPLVLLLHGFPESWYSWRHQFAP
                     LAGAGYRVVAPDQRGYARSDRPEAVDAYTLPHLVGDVVALVSALGEESAVMVGHDWGAP
                     VAWATAMMRPDLVRGVAGLSVPPVPPAMMPSVSSSRAVYGDGFYQAYFQEPGVADAELA
                     ADPASTLRRLLVGASGDAPFDEPRLWIVPEGESALGSLPEPEELPSWLTEEDLAAFTAD
                     YSDPGAFTGPLNWYRNIDRNQGLMSPFQGRVIDVPSLYVGGDKDLVRAMRGVPELLENL
                     SLVAPGLHACVTLPGCGHWTQQERPEEVNAALLDFLAAVHGS"
     aSDomain        7018..7863
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NGM33_RS27180_Abhydrolase_1.1"
                     /evalue="1.60E-33"
                     /label="NGM33_RS27180_Abhydrolase_1.1"
                     /locus_tag="NGM33_RS27180"
                     /protein_end="305"
                     /protein_start="23"
                     /score="108.3"
                     /tool="antismash"
                     /translation="PLVLLLHGFPESWYSWRHQFAPLAGAGYRVVAPDQRGYARSDRPE
                     AVDAYTLPHLVGDVVALVSALGEESAVMVGHDWGAPVAWATAMMRPDLVRGVAGLSVPP
                     VPPAMMPSVSSSRAVYGDGFYQAYFQEPGVADAELAADPASTLRRLLVGASGDAPFDEP
                     RLWIVPEGESALGSLPEPEELPSWLTEEDLAAFTADYSDPGAFTGPLNWYRNIDRNQGL
                     MSPFQGRVIDVPSLYVGGDKDLVRAMRGVPELLENLSLVAPGLHACVTLPGCGHWTQQE
                     R"
     gene            complement(7992..9008)
                     /locus_tag="NGM33_RS27185"
                     /old_locus_tag="NGM33_27185"
     CDS             complement(7992..9008)
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013152193.1"
                     /locus_tag="NGM33_RS27185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27185"
                     /product="methyltransferase"
                     /protein_id="WP_130397243.1"
                     /transl_table=11
                     /translation="MSASAPPSPSATKLFELITASWVAAAVSAAAELGVADAMTFKPLP
                     VDEIAERIGADADALHRLLRACADLDLVEEGPRRHFALTGLGRALRGDAADSMRGYARW
                     VGSQTERSTMAHLAQAVRTGRSVFEQVHGRTAWAYLDEHPETAAVFDAGMTDISAQLTR
                     GVAGSYDFGAHHTLVDVGGGRGRLLAIVLSAHPGLRGVLFDRSDVVAHAEPVLEEVRDR
                     CRVVSGDFLSFVPEGGDAYLLSNVIHNWGDQDAARILSHCREAMTRDGRVLLAEVVVPD
                     SPGPARTAKFMDLSMLAHCDGKQRTRAQFADLFEQAGLKLSRVLPSFGTSIVEGVRA"
     misc_feature    complement(8975..8989)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(9087..9102)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.13"
                     /tool="antismash"
     misc_feature    9120..9138
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.36"
                     /tool="antismash"
     misc_feature    complement(9122..9136)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.65"
                     /tool="antismash"
     gene            9204..9719
                     /locus_tag="NGM33_RS27190"
                     /old_locus_tag="NGM33_27190"
     CDS             9204..9719
                     /EC_number="1.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017608305.1"
                     /locus_tag="NGM33_RS27190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27190"
                     /product="nitroreductase family protein"
                     /protein_id="WP_275102144.1"
                     /sec_met_domain="PF00881 (E-value: 1e-12, bitscore: 46.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTRRAVRAFTDRPVDDSLLDPMLDAMLAAPSASNKQAWAFVAVR
                     ERRRLRLLRAFSPGIIELPPLVVAACFDRSRAVGGSSNSTDSGDSWDEGMLCVAMAVEN
                     LLLAAHCLGLGGCPSGSFRAGPVRRLLGLPDHLEPLLLVPIGHPARPLDPAPRRDPNEV
                     VSHERWGT"
     gene            9700..10017
                     /locus_tag="NGM33_RS27195"
                     /old_locus_tag="NGM33_27195"
     CDS             9700..10017
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017566636.1"
                     /locus_tag="NGM33_RS27195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27195"
                     /product="DUF6092 family protein"
                     /protein_id="WP_130397245.1"
                     /transl_table=11
                     /translation="MSAGEPDVRQVGEELLLLAAYLLSSGRGLLDEPRQYGTFRCLDAA
                     RRVLALAAGTGPHHPELDALRGRMDDVMCGPMGDHELDTLLDQLCERLASVLEDPDVIP
                     D"
     gene            10001..10744
                     /locus_tag="NGM33_RS27200"
                     /old_locus_tag="NGM33_27200"
     CDS             10001..10744
                     /GO_function="GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013152196.1"
                     /locus_tag="NGM33_RS27200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27200"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_253797273.1"
                     /sec_met_domain="CDPS (E-value: 4.1e-72, bitscore: 240.8,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPTEPEPPPEPPDDFDVLPFTGSCRRVFERGEHALVGISAGNS
                     YFSQQRLARLLCWARGHFARVDVLYTDLHLDAMYMASGSSREHAASRANRTLRDVRRRI
                     RRAVESATAESAAVADVRVLALSQCTRLPGYREVEGRLDREYAADPRIRRCWEEHVRRV
                     VGAQPDPEGARLRAGLAYLRAELPFLLSTPEVLEVPSSVSCYHDLLPILSTLRGVTSCS
                     HPEQGHVVVRPALRRRPAPEALAFP"
     gene            complement(10825..11847)
                     /locus_tag="NGM33_RS27205"
                     /old_locus_tag="NGM33_27205"
     CDS             complement(10825..11847)
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610345.1"
                     /locus_tag="NGM33_RS27205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27205"
                     /product="methyltransferase"
                     /protein_id="WP_130397247.1"
                     /transl_table=11
                     /translation="MDEAAVRAERTDLPLNQLVASAMLMHAVVAIVELDVVEDLADGPR
                     PVADLVRRTGIPEQTLTAVLRAGTVSGLLSEPAPGSFALTAAGGHLRAGDPSGLYDLFR
                     MCTHGAFLQSWTCLSQAVRSGRTAFEVHTGRPLFAYLEEERGDAAALFRRAMVTSVAAD
                     TLLEKVDLSGAERVADLGGGEGSMLAALLQHHPRMEGVLFDLPHVVSGAGPLLRERGVA
                     DRCAVVGGSFFDGVPTGVDVYLMARVMQNWPRPEAVRILRNVRAAMGERSRLLIIGHLP
                     QREGATPFLQAMSLYMLVLYGAPLRTAEEYRELFAEADLALHAVHRVEDGESVMDVRRA
                     "
     misc_feature    11971..11982
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.16"
                     /tool="antismash"
     gene            complement(12023..12880)
                     /locus_tag="NGM33_RS27210"
                     /old_locus_tag="NGM33_27210"
     CDS             complement(12023..12880)
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013152198.1"
                     /locus_tag="NGM33_RS27210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27210"
                     /product="NAD-dependent protein deacetylase"
                     /protein_id="WP_130397248.1"
                     /transl_table=11
                     /translation="MRNTLDDPAALAARMREVLGSGPVVALTGAGLSTDSGIPDYRGPD
                     SPPRKPMTYQQFVGDAAFRRHYWARNHVGWRHMHRTRPNDGHRALAALEAGGALAGVIT
                     QNVDTLHGAAGSRRVIDLHGRYDRVICLACSAVTSRESLAERLGALNPDFADGVPDVEI
                     APDADAVLASTEGFRVADCEGCGGVLKPDIVYFGENVPKARVLEGYAMVDGARALLVAG
                     SSLTVFSGRRYVKRAVEQGKPVVVLNRGATRADDVAALTVDAGCSEVLTALVRAYEAEG
                     AAPV"
     gene            complement(12949..13575)
                     /locus_tag="NGM33_RS27215"
                     /old_locus_tag="NGM33_27215"
     CDS             complement(12949..13575)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020545671.1"
                     /locus_tag="NGM33_RS27215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27215"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_130397249.1"
                     /transl_table=11
                     /translation="MRITLTEFVTLDGKSQGPGSPEEDTSDGFTRGGWLVPHMDATFVQ
                     RASDWLDLADGLLLGRRTYEAFARDWPRITDPEDPFTERMNNLPKYVVTNTLTEGAWHP
                     TTVLRGDPARTVGELRSRPGRELQIHGSARLGDSLLSAGLVDVLRLVVAPTVIRSGRRL
                     LTDRGAPLDLRLAHHEATPNGLLLLEYEIVGRARRSRYEGVTDLV"
     gene            complement(13572..14066)
                     /locus_tag="NGM33_RS27220"
                     /old_locus_tag="NGM33_27220"
     CDS             complement(13572..14066)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (15-127). E-value:
                     2.7e-10. Score: 32.8. Matches aSDomain:
                     nrpspksdomains_NGM33_RS27220_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020545672.1"
                     /locus_tag="NGM33_RS27220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27220"
                     /product="SRPBCC domain-containing protein"
                     /protein_id="WP_253797274.1"
                     /transl_table=11
                     /translation="MNPGSDIDPDLDLALERVIRAPRETVWRAWTDPSQLARWWVPAPS
                     RCRVDRLEPRPGGAFVTRLSDDGAGFLPHTDACFLVVDEPERIVFTNAIDGTWRPAAPA
                     PVAMTAAIALEAHPEGTRYRVLVRHGDPEARARHEKLGFLEGWGSVADQLTALAERTVS
                     P"
     aSDomain        complement(13686..14021)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NGM33_RS27220_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.70E-10"
                     /label="NGM33_RS27220_Polyketide_cyc2.1"
                     /locus_tag="NGM33_RS27220"
                     /protein_end="127"
                     /protein_start="15"
                     /score="32.8"
                     /tool="antismash"
                     /translation="ERVIRAPRETVWRAWTDPSQLARWWVPAPSRCRVDRLEPRPGGAF
                     VTRLSDDGAGFLPHTDACFLVVDEPERIVFTNAIDGTWRPAAPAPVAMTAAIALEAHPE
                     GTRYRVLV"
     gene            complement(14063..14401)
                     /locus_tag="NGM33_RS27225"
                     /old_locus_tag="NGM33_27225"
     CDS             complement(14063..14401)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009081175.1"
                     /locus_tag="NGM33_RS27225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27225"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_130397250.1"
                     /transl_table=11
                     /translation="MAQYSAELDGVLVTLADPTRRAVVRRLGRGPSTVGDLAREFPITL
                     PSFMKHVRKLESNGLIRTVKTGRVRTCVLDRERLALVSDWLSEQHRIWEERTDRLEQFV
                     TDPQGDRP"
     gene            complement(14594..17974)
                     /locus_tag="NGM33_RS27230"
                     /old_locus_tag="NGM33_27230"
     CDS             complement(14594..17974)
                     /EC_number="6.4.1.1"
                     /GO_function="GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0009374 - biotin binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006090 - pyruvate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610342.1"
                     /locus_tag="NGM33_RS27230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27230"
                     /product="pyruvate carboxylase"
                     /protein_id="WP_130397251.1"
                     /sec_met_domain="ATP-grasp (E-value: 3e-07, bitscore: 28.5,
                     seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 4.5e-11,
                     bitscore: 41.0, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="HMGL-like (E-value: 4e-27, bitscore: 93.8,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRKVLVANRGEIAIRALRAGYELGARTVAVFPHEDRGSLHRLKA
                     DEAYQIGEPGHPVRAYLSVDEIVGAARRAGADAVYPGYGFLSENPELARACERAGITFV
                     GPPADVLELTGNKASAVAAAREAGVPVLESSEPSDDVEALVSAAERIGFPLFVKAVAGG
                     GGRGMRRVQEPERLREAVEAAMREASAAFGDATVFLERAVVDPRHIEVQILADGEGGVV
                     HLYERDCSLQRRHQKVIELAPAPNLDPDLRDRICADAVRFARRIGYRNAGTVEFLVGAD
                     GSHVFIEMNPRIQVEHTVTEEITDVDLVQSQLRIASGETLSDLGISQEGVYVRGAALQC
                     RITTEDPANGFRPDTGTISAYRSPGGSGIRLDGGTSAAGTEISPHFDSLLVKLTCRGRD
                     LATAVSRARRAVAEFRIRSIATNIPFLQAVLDDPDFQAGRITTSFIEERPHLLTARPSA
                     DRGTRLLTYLADVTVNKPHGERPQLVDPATKLPPLPEPAGPPPPGSRQRLAELGPEGFA
                     RWLRESPNLGVTDTTFRDAHQSLLATRVRTRDLLAAAPAVAHTLPELLSLECWGGATYD
                     VALRFLAEDPWERLAALREAVPNICLQMLLRGRNTVGYTPYPTEVTDAFVREAAETGVD
                     VFRIFDALNDVEQMRPAIEAVRATGTSVAEVALCYTSDLSDPGEKLYTLDYYLKLAERI
                     VDAGAHVLAIKDMAGLLRAPAAAKLVTALRSEFDLPVHVHTHDTPGGQLATYLAAVNAG
                     ADAVDGAVASMAGTTSQPSLSAIVAAFDHSEHATGLSLDAVNELEPYWEAVRRVYAPFE
                     AGLSSPTGRVYHHEIPGGQLSNLRTQAVALGLGEHFEEIEAMYGAADRMLGHLVKVTPS
                     SKVVGDLALHLVGAGVSPADFEADPGRFDVPDSVVGFLRGELGVPPGGWPEPLRTRALQ
                     GRSEARPAQELSEQDRAGLAEDRRATLNRLLFPGPTREFEEHRAAYGDTSVLSSADFFY
                     GLRAGEEYAVDLSPGVRLLIQLEAVGEADERGVRTVMATLNDQLRPLQIRDRALASQVR
                     SAEKADRGDPGQVAAPFAGAVTLTVAEGEAVEAGATVATIEAMKMEAAITAPVSGTVTR
                     VAIDRVQKVEGGDLLVCLG"
     misc_feature    complement(18191..18209)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.46"
                     /tool="antismash"
     gene            complement(18281..18868)
                     /locus_tag="NGM33_RS27235"
                     /old_locus_tag="NGM33_27235"
     CDS             complement(18281..18868)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013152201.1"
                     /locus_tag="NGM33_RS27235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27235"
                     /product="DUF488 family protein"
                     /protein_id="WP_130397252.1"
                     /transl_table=11
                     /translation="MAPPFLTVGHSDRTFGEFAALLHENGVHVVVDVRKLPGSRRNPQF
                     DEDVLSESLRRVGVRYSRVAELGGRRPVARDVAPEVNGFWRNRGFHNYADHGLSAEFGS
                     GLARLREAGADHRAAVMCSEAVWWRCHRRIIADHLLARGHEVLHVMAAHRVDAARLTPG
                     AVVHTDRTVTYPARSSDANGDGDAREDGSPRA"
     misc_feature    18823..18836
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.36"
                     /tool="antismash"
     gene            complement(18874..19095)
                     /locus_tag="NGM33_RS27240"
                     /old_locus_tag="NGM33_27240"
     CDS             complement(18874..19095)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573914.1"
                     /locus_tag="NGM33_RS27240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27240"
                     /product="DUF2945 domain-containing protein"
                     /protein_id="WP_130397253.1"
                     /transl_table=11
                     /translation="MTRRFHVGDHVSWNSEAGRVSGTITRVHTSDFAFRGRTRRASEDE
                     PQYEIKSDRTDHVAAHKDGALTRVSGDG"
     misc_feature    19061..19073
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.88"
                     /tool="antismash"
     gene            complement(19190..19861)
                     /locus_tag="NGM33_RS27245"
                     /old_locus_tag="NGM33_27245"
     CDS             complement(19190..19861)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013152203.1"
                     /locus_tag="NGM33_RS27245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27245"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_130397254.1"
                     /transl_table=11
                     /translation="MTAEPFHDEESALPLRERKKLRTRRVLADTALRMFLERGFDQTTL
                     DDLVAAAEVSVRTFFRYYSSKEEVALAAEGELWEAYAAEVERMSVTGPVLPLLRDCYAD
                     AVRGLPDDWTERYLATRKLVAHNPVLNAHHAGAVQALRVRLTELLEEETGADSRADVRL
                     RLVSEMALAAVRCGSMNWVRAYRHSDRTGDAATLVAEVTAAFDALPRALTLSPDTLAPF
                     D"
     gene            19984..20457
                     /locus_tag="NGM33_RS27250"
                     /old_locus_tag="NGM33_27250"
     CDS             19984..20457
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013152204.1"
                     /locus_tag="NGM33_RS27250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_27250"
                     /product="hemerythrin domain-containing protein"
                     /protein_id="WP_253797275.1"
                     /transl_table=11
                     /translation="MSDRTAAPVPEGQRIEALGDQLVKIHDMLRGELASLRRDLAGGGA
                     PSGVPAPLDEQLRKKCLSFCDFLHGHHTAEDEGVLPGLARSHPGLAPVLERLTREHVLV
                     SRSLDRIRALLEGGEAAGLRAEVERLAAEVEAHLDYEERQIVEALNSYGPVTL"
ORIGIN
        1 gactacgcca ccctcctgcg cgagcggctg ctcgaccccc tggggatgga cgacacgacc
       61 ctgcccgcgt ccgggaacga cctgtccgag gacgcgaccc ggggctacac cgacaggggg
      121 cgcgtggccg acccctggct ggcccgcgcc tacgcaccca ccggaggcgt gcgctccacc
      181 cccgctgaca tggcgctctt cgccggggcg ctgctggagg gcaccgcgcc gggagcggcg
      241 gccctggaac cgcgctggga cggcggaagt gacggccgga tcgggttcgc ctggatcacg
      301 caggagcacg gcggcaccga ggtcacctgg cacaacggcg gcaccggggg cttcgcctcc
      361 atggtcgccc tggaccggga gggcgggcgc gcggtgctgg ccttcggcaa cacgaccacc
      421 ggactggaag acgccgccct ggaactgctg acggaggacg cccgatgaac gtgacggacg
      481 tgctgaccta cgccggggcc gcgttcctca acggcatctg cgtcgtgagc gcggtggacg
      541 tcctcctgcg gatccgcgac cggggcaggt tccgcttcgc ggaccgctgg gacgtgctga
      601 accggacggc ccacaccctc ttcttcctgg tgctctcgct gctgctgacc acgtgggcgt
      661 ccttccccgt ggcggtctgg tacctggacg tggccctgag cgcgggggcc gccgcggtcg
      721 cggtgctgtg ctggcccggc ctgcccgcgc gcgccgccga cgcgggcgcc gcctcccggc
      781 gccactccgc ggtcggcacg ctggtcttcc tggcggtggt cctcgcggtc ttcctccttt
      841 tcgcctgaac cgagcatccg tgcgaaaagc gcgcaatgca ggggtatgtc agatttaaga
      901 agagcggaaa aagtgggatg ccgcacttct ccgccgtctg accggggttc ctcgcgagaa
      961 agcccacgtg cctttcgccc gtggtctacg gtgatttccg tccgccctcg aattccccgg
     1021 gggaaaaccg ggtggacctc ccctgcccgg agaccgggcg acgggaccgg gcacggcccc
     1081 gctcccttcg cacgattgcc ccgcgaggaa cccgcccatg ccatttcacc cgtccgaccg
     1141 acaacggcgg ccaccgcgcc ccggacgaca ggccctggcc gccctgttcg ccgtgaccgc
     1201 gctggcggtc ccggcctggt cctgggcggt cgccacggcc caccccgacg cccgccagag
     1261 cgtggccctg gccgtcggcg cggccggagc cgccctgtgc gccgccgtca cctcggcggc
     1321 gcaccaggcc gccgccgccc gcgccgcgcg cgagcgcggc acccgggtcg acgccaccgc
     1381 ccaggccctc gaacgcgagg ccgagcacct ggtggaccag ctcctgcccg ccctcaccga
     1441 gggcctgcgc gcgggccgca ccgcgcgcga ggtcctcgcc gagcaccccc agccccgcca
     1501 cgtcgcgctg caccggctca cccacgccgt caccgcagaa ctcgacaccg cgcgcgtgcg
     1561 cgccgccgac gccctcgcca ggcgcaccgc gctggaggag cagatcgccg acctcgaccg
     1621 cgtcggcctg ccgctcatgg tcgcccgcgt gcgcgaggac cgcgtcggcg ccgccgaggc
     1681 actgcgggag gaactgcccc ccgtccacga caccctcgcc cgcctgcgcg cgcacacgct
     1741 ggaggagctg ttggccgccg cccgccgctc cgcctcggcc atggagaccg ccgccgcctc
     1801 cggcgcccgc atccaggccc acctgacctc cctgctggcc aggctccgcg aactccagga
     1861 ccgctacggc gacagccccg gcgtcttcgg cgacctcctg gacatcgacc acggcgtctc
     1921 ccgcacgggc cgcctcgccg acggcctcgt cgtcctggcc gggggccgct cgggccgccg
     1981 ctggacccgg cccatcgcga tggagagcat cctgcgcggt gccatgggcc gcatcagcgc
     2041 ctaccgccgc gtgcgcctgc acaacaccag caccgcctcc atcgccgggc acgccgccga
     2101 gggcgtcatg caggccctgg ccgaactcat ggacaacgcc gccaacttct ccgcccacgg
     2161 caccgaggtg cacgtctacg tccaggagga ggacaccggc ctgtccgtca ccgtcgagga
     2221 cagcggactg ggtatgcgcg tgcgcgagcg caggctcgcc gagagcctgg tcaccgagcc
     2281 ccgcgacctg tccacgctgc gcggcacccg cacgggtctg gcggtcgtgg gccgcctcgc
     2341 ccacaagcac gcgctcggcg tcagcttccg cccctcggcc cgcggcggcg tcggcgtcgt
     2401 cgtcctcgtc ccgccgcacc tggtcaccga gtcccagccc gcccccggcg gnnnnnnnnn
     2461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngtcctggcc gccagggtgt gcgcggcccg
     2581 tccggacgcg gccccggcgg cggcgcgcgc ccccgccccc gcgcccgccc gcgccgcctc
     2641 cgggctgccc cggcggcggc gcggccagac cctcgccgcg gcgctgcggg aggagcccga
     2701 ccagctctcc gccggtccgg ccacacccgg acccggcggc gaccccggca ccaggttcgc
     2761 gtccttccgc aacgcccgcc agccacaacg agccgaagag tagagaagag aaacggaggg
     2821 aggggcacgg accgggcccg cgcgcggctg ccccgcgacc ccgatgaaca ccatggacac
     2881 cagcctcgac tggcttctgg agaacctgcg ccacgggaca ccgggcatcc gccacgtgct
     2941 cgtgctgtcc agggacggac tcaggatgtg ccacacccgc gaactgcaca ccgaccgcgc
     3001 cgaccagctc gccgccatcg ccgcgggcat ccagagcctg tccctgagcg cctccgcaga
     3061 gttcggcgac cgcggcggcg cgggccaggc catggtcgag ttcggcggag gcgtcctgct
     3121 catcatccgc gccggggagg gcgcccacct ggcggtggtc gccgccgggg aagccgacgt
     3181 cggcgtgatc ggccacagca tgaacgcact cgtcggacgg atcggcggct tcctgacggc
     3241 cgccccgcgc cggagcgaac ggctccgagt gggcgccgag cagcggtgac ccaccacgac
     3301 tccctccggg cagaggcccc cgaccgcctg tacaccgtga ccggcgggcg ctccgacgcg
     3361 gacacccgcg tgttcgactc ggtcaccctc gtcgtcgccg agtgcgaccc cgtgcccggc
     3421 atgcagtccg agcacgccgc gatcctgcgc ctgtgcgcgt acccgaccgc cgtggtggag
     3481 ctgtccgcgg agctgcggct ccccgtcagc gtcgtgcgga tcctcctgct ggacctgctg
     3541 gacacgggac gggtgtcggc ccgccatccg gcggccctca cccggcagga ggccgggcac
     3601 gaccccgaga ccctgaagca ggtgctcctt gccctccaac gcctctgaac ggctggccgg
     3661 accgcgccgg gccccgctcg ccgcgacggc cgacaacgcg ctcaagatcg tcgtcgtcgg
     3721 cgggttcggc gtcggcaaga ccaccctggt cgactccgtc agcgagacgc gcccggtgag
     3781 caccgaggag gtcatgaccc aggccagcgc cgggatcgac gacctcagcg ccgtccgcga
     3841 caagcgcacc accaccgtgg ccttcgactt cggacgcatc accgtggacg agcggcgcgt
     3901 gctctacctc ttcggcgccc ccggccagaa gcggttctgg ttcctgtgga accagctgtt
     3961 cgagggcagc ctgggcgcgg tcgtcctcgt ggacaccgac cgcatccggg actcctggta
     4021 cgccgtggac cggctcgaac accaccgcac gcccttcgtc gtcgcggtga accgcttcgg
     4081 ccccgggccc gccctgcccg aggtgcggcg cgccctggac ctgtccgagc gggtccccgt
     4141 ggtggactgc gacgcccgca gccgcgagtc cagccgcgac gtcctgatca ccctcgtcca
     4201 gcacgtgtcc ggacccgtcg ccgggtaccc gtccgcgccg ccgacggagt tcgcgcccgg
     4261 gtcagggcag gcgtccgcgc cggcgccgac gtccggcccc gcgtccgtac ccgcgccgac
     4321 ccaggaggag acgacgtgaa ccacagcccg ggcccggagg ccgcggcacc ggccagcagc
     4381 ggtccgccgc ccccctcccc ggaccacgcg ggcgccgccc gcctgtacgg acccgacgtc
     4441 gcccgcgacc cggccgggct ctacgaggag ctgcgcgggc gctacggccc ggtcgcgccc
     4501 gtgctgctcg acggcgacgt tccggcgtgg ttcgtcatgg gctaccggga gctgcaccac
     4561 gtcaccagca ggcccgagtg gttcgcccgc gactgccgcc gctggaacca gtgggaccgc
     4621 gtcggccggg actggccgct catgccctac gtgatgtgga cgccctcggt catgttcgcc
     4681 gagggtgccg agcaccagcg gcgcgcgggc gcgatcggcg acgccctgga cgccgtggac
     4741 cgcaccgacc tcagggccct gtgccagcgg gccgccgacg gcctcgtcga cgccttccgc
     4801 gcggagggcg aggccgacct ggtctcccag tacgcgcacc gcatccccgc gatggtggtc
     4861 gccaggctct acggcctgcc ggaggcggag gtcccggcgc tggtgcgcga cgtcgtgctc
     4921 tcgctcgacg ccaccgccga cgcgggcggc gcccaccagc gcctgcgcgc ccgcctggac
     4981 gccctggccg ccgaccgccg cgccgcgccc cgcgacgacg tgccctcgcg gctgctgctg
     5041 cacccggcgg gcctgagcga cgccgaggcg gccatcgacc tgctggtggt cctcgccgcg
     5101 gcccaggcgc ccaccggcaa ctggatcggc aacaccctgc tcctgatgct caccgacgac
     5161 cagttctcgc tcaccctcca gggcgggcgc ggcagcgcgg gcgaggccct caacgaggtg
     5221 ctgtggaaga acacccccac gcagaacttc atcggccgat gggccgtgca ggcctgtgag
     5281 ctgggcgggc gcggcatccg acgcggcgac atgctggtgc tgggactgtc ggcggccaac
     5341 gccgaccccc gcctgcacgc ggggctcccc gacggccacg gcggcaaccg cgcgcagatg
     5401 tccttcggcc acggcgagca cgggtgcccc ttcccggcgc cggagatcgc ggagacgatc
     5461 gcccgcacgg cggtggagag cctgctggac cggctgccgg acgtgcggct gggggtgcct
     5521 ccggagcggc tggagtggcg gccgtcgctg tggatgcgcg gactgttcga gctcccggcg
     5581 cgtttcacgc cgcagcggta gggggtggtc ggaagtgttg ccggcgtgac gcgaggggtc
     5641 tggccacggg atccgctgga gggaatatca cgaggtttct gggtggaatc ccttttatgg
     5701 gagatatgtc gattgtggga cttcggtggt cattccgtgc cgccgtccac ggggcgcggt
     5761 ccccgcggac ggcggcacgg gccgcgaccg gccgcggctc aggcgagggc gttctccccg
     5821 gtcagctcgg cggagaacgc ccacaggcgc tcggcctgcg cgggatcggc cgcgtggtcg
     5881 cgcacgccct ccacaccggg ctcggttccg gcgggcacgg ccacgtcgca gtcctcgcag
     5941 tacaccccgc ccatcccggc cagcctcggc gaggtggccg cccacacctg ggtggccgcg
     6001 ccctgctccg gcgtcttgaa ccgggggtcg atcagctcac cgttcccgtc gacccacccc
     6061 gcgtcgacca tctcccgccg cgtcatgtgc cgctgcaagg gggtgaggat cgcgcccggg
     6121 tgcagggaga aggcccgcac cccgaggggt tctcccagcc ggtccaggtg gagggcgaac
     6181 agggcgttgg cggtcttgga ctgcccgtag gccagccacc ggtcgtagcc ccgggcgaac
     6241 cacgggtcct cccagcggat cggcgaggcc tggtgcgcgc ccgaggacac cgagaccacc
     6301 cgcgccccgc cctcggccag ggctggccag agccggttga ccagggtgaa gtgccccagg
     6361 tggttggtgg cgaactggta ctcccagccg ggtccggcgg cggcccgggg gcaggccatc
     6421 accccggcgt tgttgacgag gacgtcgatc gcgcgccccg tcctgaggaa gcgttcggcg
     6481 aaggcgcgca cgtcgtcctg atcggacagc tccaggccgt cgacctccac gcccccgatt
     6541 ccggccaggg cctcggccgc cgcctggggc cggcgcgcgg gcacgacgac gcgggcgccc
     6601 gcccccgcca gggcccgggt ggtctccagg ccgatgcccg agtacccgcc ggtgacgacg
     6661 gccagccgtc cggtcaggtc gattccgtcc aggacctcgc gcgcggtgct gcgcctcccg
     6721 aagcccgagc cgatccttcg ctgtggtgtg gtcatggacc ggaccctagg tactggagcg
     6781 cgctccactt caagcggcgc aggtgggagg ggacgcccac ccggggacga ggggacgccc
     6841 acccggggac acgtccggcc cccgctcccg gggagccggg agggcccggc cccgctggga
     6901 tagcgtgacc gtgaccccca cccctcagcg atgaggagcg cgtacgccat gaacgtggaa
     6961 cacagggacg tcgaggtcaa cggaatccgg ttgcacgtcg ccgagcaggg cggcggaccg
     7021 ctcgtcctgc tcctgcacgg cttccccgag agctggtact cctggcgcca ccagttcgcc
     7081 ccgctggccg gggccgggta ccgcgtggtc gcccccgacc agcgcggtta cgcccgcagc
     7141 gaccggcccg aggcggtgga cgcctacacc ctgccccacc tggtcggcga cgtcgtcgcc
     7201 ctcgtctccg cgctggggga ggagagcgcg gtcatggtcg gccacgactg gggggcgccg
     7261 gtggcctggg ccaccgccat gatgcgcccc gacctggtcc gcggcgtggc gggcctgagc
     7321 gttccgcccg ttccgccagc catgatgccg tcggtctcgt cctcccgcgc cgtctacggc
     7381 gacggcttct accaggccta cttccaggag ccgggcgtcg ccgacgccga gctggccgcc
     7441 gaccccgcct cgaccctgcg ccgcctcctg gtcggggcct ccggcgacgc ccccttcgac
     7501 gaaccccggc tgtggatcgt gcccgagggc gagagcgcgc tgggctccct gcccgaaccg
     7561 gaggagctgc cctcctggct caccgaggag gacctggccg ctttcacggc cgactactcc
     7621 gaccccggcg ccttcaccgg tccgctcaac tggtaccgca acatcgaccg caaccagggg
     7681 ctcatgtcgc ccttccaggg gcgcgtcatc gacgtgccct cgctgtacgt gggaggggac
     7741 aaggacctgg tcagggccat gcgcggcgtt cccgaactcc tggagaacct gtcgctggtc
     7801 gcaccggggc tgcacgcctg cgtcaccctg cccggctgcg gccactggac ccagcaggag
     7861 cgccccgagg aggtcaacgc ggccctgctc gacttcctcg ccgccgtcca cgggagctga
     7921 gccgcccgtg cccgtgcccg tgcgcgctgg agccggtgcg cacgggcacg gtggcggcac
     7981 cggtgcgccg ctcaggcgcg caccccctcg acgatgctgg tcccgaagct gggcaggaca
     8041 cgggacagct tcagcccggc ctgctcgaag aggtcggcga actgggccct ggtgcgctgc
     8101 ttgccgtcgc agtgggcgag catgctcagg tccatgaact tggcggtccg ggcgggaccc
     8161 ggggagtcgg gcaccaccac ctccgcgagc aggacgcgcc cgtcgcgggt catcgcctca
     8221 cggcagtggg agaggatccg cgcggcgtcc tggtcgcccc agttgtggat gacgttcgac
     8281 agcaggtagg cgtcgccccc ttcgggaacg aaggagagga agtccccgct cacgacgcgg
     8341 caccgatcac ggacctcctc cagcaccggt tcggcgtggg cgaccacgtc ggaccggtcg
     8401 aagagcacgc cgcgcagacc gggatgggcc gacagcacga tggccagcag cctgccccgg
     8461 cccccgccga cgtccacgag ggtgtggtgc gcgccgaagt cgtaactgcc cgccacaccc
     8521 cgggtgagct gggcggagat gtcggtcatg cccgcgtcga agaccgccgc ggtctcgggg
     8581 tgttcgtcca ggtaggccca ggccgtccgg ccgtgcacct gctcgaacac cgagcgtccg
     8641 gtccgcaccg cttgggccag gtgggccatg gtggaccgct cggtctggct gccgacccac
     8701 cgggcgtagc cgcgcatgga gtcggccgcg tccccgcgca gggcgcggcc gagcccggtc
     8761 agggcgaagt gccgccgcgg cccctcctcg accaggtcga ggtcggcgca ggcgcgcagg
     8821 aggcggtgga gggcgtcggc gtcggcgccg atcctctcgg cgatctcgtc gacgggcagg
     8881 ggcttgaagg tcatggcgtc ggcgacaccg agttcggccg ccgcgctcac cgcggccgcc
     8941 acccagctgg cggtgatgag ctcgaacagt ttcgtggccg aaggactcgg gggtgcagat
     9001 gcggacatcg cggtcctttc aggtggtgcc cctccggggg tgcggagagg ggcggccaga
     9061 tgcgcctgtg cggcatccat ggagccgtat aacagggtaa actacggagc gtgctcgaaa
     9121 aatcgcataa tgtggacaca ggttcgagtg agacggatac gaaccagtgc tcccctcagc
     9181 ggtcatcaca cgtcctacag accctgacca cccgccgtgc cgtacgcgcc ttcaccgacc
     9241 ggccggtgga cgactccctc ctcgacccca tgctggacgc catgctcgcc gccccctcgg
     9301 cgtccaacaa gcaggcgtgg gccttcgtcg ccgtccgcga gcggcgcagg ctgaggctgc
     9361 tgcgcgcctt ctcccccgga atcatcgaac tcccgcccct ggtcgtggcg gcctgcttcg
     9421 accgctcccg tgccgtgggg ggctcaagca actcgacgga ctccggggac tcctgggacg
     9481 agggcatgct ctgcgtcgcg atggcggtgg agaacctcct cctggcggcc cactgcctgg
     9541 ggctgggcgg gtgcccgtcg gggagttttc gcgccggccc cgtccgcagg ctgctgggcc
     9601 tgcccgacca cctggaaccc ctgctcctgg ttccgatcgg gcaccccgcc cggccgctcg
     9661 accccgcacc ccgacgagac ccgaacgagg tggtcagcca tgagcgctgg ggaacctgac
     9721 gtccgacagg tcggcgagga actcctcctg ctcgccgcct acctgctcag cagcggccgc
     9781 ggcctgctgg acgagccacg gcagtacggc acgttccgct gcctggacgc cgcccggcgc
     9841 gtcctcgccc tcgcggccgg aaccggcccg caccatccgg aactcgacgc cctgcgcggt
     9901 cgcatggacg acgtcatgtg cgggccgatg ggcgaccacg aactggacac cctgctcgac
     9961 cagctgtgcg agcggctggc atccgtcctg gaggatcccg atgtcatccc cgactgagcc
    10021 ggagccgccc ccggagcccc cggacgactt cgacgtcctg cccttcaccg gttcctgccg
    10081 tcgcgtgttc gagcgcggag agcacgccct cgtcggtatc agcgccggga acagctactt
    10141 cagccagcag cggctcgcac ggctcctgtg ctgggcgcgg ggccacttcg cccgggtcga
    10201 cgtgctctac accgacctgc acctggacgc catgtacatg gcgtccggca gcagcaggga
    10261 gcacgccgcg tcccgggcga accggacgct cagggacgtg cggcggcgca tcaggcgcgc
    10321 ggtggagtcc gcgaccgcgg agtcggccgc cgtggcggac gtgcgcgtcc tcgccctgtc
    10381 gcagtgcacg cgcctgcccg gctaccggga ggtcgagggg cgcctcgacc gggagtacgc
    10441 cgccgatccc cgcattcgcc gctgctggga ggagcacgta cgccgggtcg tgggcgccca
    10501 gccggacccg gagggcgcca gactgcgcgc cgggctcgcc tacctgcgcg ccgaactgcc
    10561 cttcctgctc agcacccccg aggtactgga ggtaccgtcc tcggtctcct gttaccacga
    10621 cctgttgccg atcctgtcca cgctgcgcgg cgtcacctcc tgttcccacc ccgaacaggg
    10681 ccacgtggtc gtccgaccgg ccctcaggcg ccgtcccgcc ccggaggcgc tggcgttccc
    10741 gtgaaccgcc gtccggtggc gccccgggcg ccaccggacg gagcggtcgc gggcggagcc
    10801 ccgtcccggc cgggacgggg cccgctacgc gcggcggacg tccatgaccg actccccgtc
    10861 ctcgacccgg tgcacggcgt gcagcgcgag gtcggcctcg gcgaacagtt cccggtactc
    10921 ctccgccgtg cgcagcgggg cgccgtagag cacgagcatg tacaggctca tcgcctggag
    10981 gaagggggtg gcgccctccc gctgcggcag gtgcccgatg atcagcagcc gggaccgctc
    11041 acccatcgcc gcgcggacgt tgcgcaggat ccgtaccgcc tccggccggg gccagttctg
    11101 catcacccgt gccatcaggt agacgtccac ccccgtgggc accccgtcga agaagctgcc
    11161 ccccaccacg gcgcaccggt ccgccacgcc ccgttcccgc agcagcggcc cggccccgga
    11221 caccacgtgc gggaggtcga acagcacccc ctccatgcgc gggtggtgtt gcaggagggc
    11281 ggccagcatc gagccctctc cgccgccgag gtccgccacg cgctcggctc cggacaggtc
    11341 caccttctcc agcagggtgt cggcggccac ggacgtgacc atcgccctgc ggaacagggc
    11401 ggctgcgtca ccccgctcct cctccaggta ggcgaacagc gggcggccgg tgtgcacctc
    11461 gaaggccgta cggccggaac gcaccgcctg cgacaggcag gtccacgact ggaggaaggc
    11521 gccgtgcgtg cacatccgga agaggtcgta caggccgctg gggtcaccgg cgcgcaggtg
    11581 cccgcccgcc gcggtcaggg cgaacgaccc gggtgccggc tccgagagca gcccgctcac
    11641 cgtcccggcc cgcagcaccg ccgtcagggt ctgctcgggg atcccggtgc ggcggaccag
    11701 gtccgccacc gggcgcggcc cgtccgccag gtcctccacc acgtccagtt cgactatcgc
    11761 gacgacggcg tgcatgagca tcgccgacgc caccagttgg ttcagcggca ggtccgtgcg
    11821 ctccgcgcgt acagcggcct cgtccatggc acccacagtc ggtcctcccc gggggacgtc
    11881 gtcatcgggg ccggcgcggc ctccctcccg ggacacggcg ccgacctctc aagactacgg
    11941 ggagtacgcg gacatgttct cggggttgtg gaaaacgtaa ccgggcggga aggtcgcgag
    12001 gaccggggcg acgagggccg gatcagaccg gggcggcgcc ctcggcctcg taggcgcgca
    12061 ccagggcggt gagcacctcg gagcagcccg cgtcgacggt gagcgcggcg acgtcgtcgg
    12121 cgcgggtggc gccccggttg aggaccacca ccggctttcc ctgttcgacg gcgcgcttga
    12181 cgtagcgccg ccccgagaag acggtcaggg acgaccccgc caccagcagc gcccgcgcgc
    12241 cgtccaccat cgcgtagccc tccagcacgc gcgccttggg cacgttctcg ccgaagtaga
    12301 cgatgtcggg cttgagcacg ccgccgcagc cctcgcagtc ggccacgcgg aacccctcgg
    12361 tggaggccag gaccgcgtcg gcgtcggggg cgatctccac gtcggggacc ccgtcggcga
    12421 agtcggggtt gagcgcgccc aggcgctcgg ccaggctctc gcgggaggtc acggccgagc
    12481 aggccaggca gatgacgcgg tcgtagcggc cgtgcaggtc gatcacccgc ctgctgcccg
    12541 ccgccccgtg cagggtgtcc acgttctggg tgatgacgcc cgccagggcg ccgcccgcct
    12601 ccagcgcggc cagcgcgcgg tggccgtcgt tggggcgggt ccggtgcatg tgccgccagc
    12661 ccacgtggtt gcgggcccag tagtggcgcc ggaaggcggc gtcgccgacg aactgctggt
    12721 aggtcatggg cttgcgcgga ggtgagtccg ggccgcggta gtcggggatg cccgagtccg
    12781 tggacaggcc cgcgccggtc agcgcgacca ccgggcccga gccgaggacc tcgcgcatcc
    12841 gggccgccag ggccgccggg tcgtcgagcg tgttcctcac gccttcgagg gtacgcggcg
    12901 ccccggtgtg ggcgccgccg caccaccggg ttccggccgc gcggccgttc acacgaggtc
    12961 ggtgaccccc tcgtaccggc tccggcgtgc tcggccgacg atctcgtact ccaggagcag
    13021 cagaccgttc ggcgtggcct cgtggtgcgc cagacgcagg tcgaggggcg cgccgcggtc
    13081 cgtcagcagg cgccggccgc ttcgtatgac ggtgggcgcg accaccaggc ggagcacgtc
    13141 gaccaggccc gccgacagca gcgagtcgcc gagccgggcg ctgccgtgga tctggagttc
    13201 ccgtcccggc cgggacctga gttcgccgac cgtccgggcc gggtctcccc tgaggacggt
    13261 cgtggggtgc caggccccct cggtgagcgt gttggtcacg acgtacttcg gcaggttgtt
    13321 catccgttcg gtgaacgggt cctccgggtc ggtgatccgc ggccagtcgc gcgcgaacgc
    13381 ctcgtaggtg cggcgtccga gcagcagtcc gtcggcgagg tcgagccagt ccgaggcgcg
    13441 ctggacgaac gtcgcgtcca tgtgggggac gagccatccg ccgcgtgtga agccgtcgct
    13501 ggtgtcctcc tccggcgagc cgggcccctg gctcttcccg tcgagtgtga cgaattcggt
    13561 gagggtgatc ctcacggcga gaccgtcctt tcggcgagag cggtcagttg gtcggcgacc
    13621 gaaccccatc cctccaggaa gccgagcttc tcgtggcggg cgcgggcctc cgggtcgccg
    13681 tgccggacga gcacccggta gcgcgtgccc tccgggtgcg cctccagtgc gatcgcggcg
    13741 gtcatcgcga caggtgcggg ggccgcggga cgccatgtgc cgtcgatcgc gttggtgaac
    13801 acgatccgtt cgggttcgtc gacgacgagg aagcacgcgt ccgtgtgcgg taggaacccg
    13861 gcgccgtcgt cgctcagccg ggtcacgaaa gcccctcccg gccgcggctc caggcggtcc
    13921 acacggcagc gggacggcgc cgggacccac catcgggcga gctgggaggg gtcggtccag
    13981 gcgcgccaca cggtttcgcg cggggcccgg atgacccgct ccaaggcgag gtcgaggtcg
    14041 gggtcgatgt cggagcctgg gttcacggcc tgtccccctg tggatcggtg acgaactgtt
    14101 cgagtcgatc ggtgcgctcc tcccagatcc tgtgctgctc ggagagccag tcactgacga
    14161 gggcgagccg ctcgcggtcg agtacgcaag tgcgcacacg gccggtcttg accgtgcgga
    14221 tgagcccgtt cgactcgagt ttgcgcacgt gcttcatgaa ggaggggagg gttatcggga
    14281 actcgcgggc gaggtcgccg acggtggagg gcccgcggcc gaggcgccgg acgacggcgc
    14341 gtcgggtcgg atcggcgagg gtgacgagga ccccgtcgag ttccgccgaa tactgtgcca
    14401 tgcggctaag tatggcagct cgtgatggtt agctcaaggg ctaagtgttg ggacgtgcgc
    14461 acgaccgtga acccacgccc gagccccggg tggatgtctc cggaaccggc cccggcccgg
    14521 ggcctccgga cagggaaggg cccggcgggc acccgcaggc gcccgccggg ccagaacgga
    14581 ccggacgtcc tgctcagccg aggcagacca gcaggtcgcc gccctccacc ttctgcaccc
    14641 ggtcgatcgc cacccgcgtg accgtccccg acacgggcgc ggtgatcgcg gcctccatct
    14701 tcatcgcctc gatggtggcc accgtcgcac cggcctccac cgcctcgccc tcggcgaccg
    14761 tcagggtcac cgcgcccgcg aagggcgccg cgacctggcc ggggtcgccg cggtccgcct
    14821 tctcggcgga ccgcacctgc gaggccaggg cccggtcgcg gatctggagc gggcgcagct
    14881 ggtcgttgag cgtggccatc accgtgcgca cgccgcgctc gtcggcctcg cccaccgcct
    14941 ccagctggat gagcagccgc acgcccggcg acaggtccac cgcgtactcc tcgcccgcgc
    15001 gcaggccgta gaagaagtcc gcgctggaga gcacgctggt gtcgccgtag gccgcccggt
    15061 gctcctcgaa ctcccgtgtc ggaccgggga agagcagccg gttgagcgtg gccctccggt
    15121 cctcggccag ccccgcgcgg tcctgctcgc tcagctcctg ggcgggccgc gcctcggaac
    15181 gcccctggag cgcccgcgtg cggaggggct cgggccaccc gccgggcggg acgcccagct
    15241 caccgcgcag gaaccccacc accgagtccg ggacgtcgaa gcgcccgggg tcggcctcga
    15301 agtcggccgg ggagaccccc gcgccgacca ggtgcagcgc caggtcgccc acgaccttgg
    15361 aggagggcgt gaccttcacc aggtgcccga gcatccggtc ggcggcgccg tacatcgcct
    15421 cgatctcctc gaagtgctcg cccagcccca gcgcgaccgc ctgtgtgcgc aggttggaca
    15481 gctgcccgcc cgggatctcg tggtggtaca cccggcccgt gggggaggac aacccggcct
    15541 cgaagggcgc gtagacccgg cgcaccgcct cccagtacgg ctccagctcg ttgaccgcgt
    15601 ccaggctcag gcccgtggcg tgctcggagt ggtcgaatgc ggccacgatc gccgacagcg
    15661 acggctggga ggtggtgccc gccatcgacg ccaccgcgcc gtccaccgcg tccgccccgg
    15721 cgttgaccgc cgccaggtag gtggccagct gtccgcccgg ggtgtcgtgg gtgtgcacgt
    15781 gcaccggcag gtcgaactcg ctgcgcagcg ccgtgaccag cttcgccgcg gccggagcgc
    15841 gcagcaggcc ggccatgtcc ttgatcgcga gcacgtgcgc gcccgcgtcc acgatccgct
    15901 cggccagctt gaggtagtag tccagcgtgt agagcttctc gccggggtcg gacaggtccg
    15961 aggtgtagca cagcgccacc tcggccaccg aggtcccggt cgcgcgcacg gcctcgatgg
    16021 ccggacgcat ctgctcgacg tcgttgagcg cgtcgaagat ccggaagacg tccacgcccg
    16081 tctcggcggc ctcgcgcacg aacgcgtcgg tcacctcggt cgggtagggg gtgtagccca
    16141 ccgtgttgcg cccgcgcagc agcatctgga ggcagatgtt ggggaccgcc tcgcgcagcg
    16201 ccgccagccg ctcccagggg tcctcggcca ggaagcgcag cgccacgtcg taggtggcgc
    16261 cgccccagca ctccagggac agcagctcgg gcagggtgtg cgcgaccgcg ggcgccgcgg
    16321 ccagcaggtc gcgggtgcgc acccgggtgg ccagcagcga ctggtgggcg tcgcggaagg
    16381 tggtgtcggt gacgcccagg ttcggcgact cgcgcagcca ccgcgcgaac ccctccggac
    16441 ccagctcggc caggcgctgg cgcgaacccg ggggcggcgg tccggcgggc tcgggcagcg
    16501 gcggcagctt ggtggcgggg tccaccagct gggggcgctc cccgtgcggc ttgttcaccg
    16561 tgacgtcggc caggtaggtg agcaggcgcg tgccgcggtc ggcggagggc cgcgcggtca
    16621 gcaggtgcgg gcgctcctcg atgaaggagg tggtgatccg ccccgcctgg aagtcggggt
    16681 cgtccagcac cgcctggagg aaggggatgt tggtggcgat gctgcggatg cggaactcgg
    16741 ccacggcccg gcgcgcccgg ctgaccgcgg tggccaggtc gcggccccgg caggtgagct
    16801 tgaccagcag cgagtcgaag tgcgggctga tctcggtgcc cgccgcggag gtgccgccgt
    16861 ccaggcggat gcccgagccg ccgggggagc ggtaggcgct gatggtcccg gtgtcggggc
    16921 ggaagccgtt ggcggggtcc tcggtggtga tgcggcactg gagcgccgcg ccgcgcacgt
    16981 agacgccctc ctgggagatg cccaggtcgg acagggtctc gccggaggcg atccgcagct
    17041 gggactgcac caggtccacg tcggtgatct cctcggtcac cgtgtgctcg acctggatgc
    17101 gcgggttcat ctcgatgaag acgtggctgc cgtccgcgcc gaccaggaac tcgaccgtgc
    17161 ccgcgttgcg gtagccgatc cggcgggcga agcgcaccgc gtccgcgcag atgcggtcgc
    17221 gcaggtccgg gtcgaggttg ggcgcggggg ccagctcgat gaccttctgg tggcgccgct
    17281 ggagggagca gtcgcgctcg tagaggtgca cgacgccgcc ctcgccgtcg gcgaggatct
    17341 gcacctcgat gtggcggggg tcgaccacgg cgcgctccag gaacacggtg gcgtcgccga
    17401 aggcggcgga ggcctcgcgc atggcggcct ccaccgcctc ccgcagccgc tcgggctcct
    17461 ggacgcggcg catgccccgc ccgccccctc cggccacggc cttgacgaag agcgggaagc
    17521 cgatccgctc cgcggcggag accagggcct ccacgtcgtc ggagggttcg ctggactcca
    17581 ggacgggcac gcccgcctcc cgggcggcgg ccacggcgct ggccttgttg ccggtcagtt
    17641 ccagcacgtc ggcgggcggg cccacgaagg tgatcccggc gcgctcgcag gcgcgggcca
    17701 gttcggggtt ctccgacagg aagccgtagc cggggtagac ggcgtcggcc ccggcccggc
    17761 gggcggcgcc cacgatctcg tccacggaca ggtaggcgcg caccgggtgg ccgggctcgc
    17821 cgatctggta ggcctcgtcg gccttgagcc ggtgcaggga gccgcggtcc tcgtggggga
    17881 agacggcgac ggtgcgggcg cccaactcgt aaccggcgcg cagcgcgcgg atggcgatct
    17941 cgccccggtt ggccacgagc actttgcgga acatggcgca ctcctcctgg tcggtcaggc
    18001 gtggtgccgt gggcgcaaga accggcaccg tcgccggggg cccgcggccg ggtggaacac
    18061 ccgtacgtta accagaagag ggttcggcgc gacccaccgg ggccgtcctt cgcgccgagt
    18121 acggcttccg gcgggcgttc cggggcgtcg gcgtgtcgcg cgggacgggg cgcggggaac
    18181 cccggcgggt gttccgtgcc gttcgcgtgc ccgaccgggt cgttccgcgt gcgccggtga
    18241 cgcctcggcg cggcgcgccc ttcctcgggc cgggctcgcg tcacgcccgg ggggacccgt
    18301 cctcccgggc gtccccgtcg ccgttcgcgt ccgaggaccg cgccgggtag gtgacggtgc
    18361 ggtcggtgtg cacgacggcc cccggagtga gccgggcggc gtccacgcgg tgggcggcca
    18421 tgacgtggag gacctcgtgg ccgcgggcga gcaggtggtc ggcgatgatg cgccggtggc
    18481 accgccacca caccgcctcc gagcacatca cggcggcgcg gtggtccgcg cccgcctcgc
    18541 gcagccgggc gagccccgat ccgaactcgg cggagagccc gtggtcggcg tagttgtgga
    18601 aaccgcggtt gcgccagaac ccgttgacct cgggggccac gtccctggcg accgggcgcc
    18661 gaccgccgag ttccgcgacg cgcgagtaac gtacgccgac acggcgcagg gattcggaga
    18721 ggacgtcctc gtcgaactgc gggttgcggc gtgaacccgg gagtttgcgc acgtcgacca
    18781 ccacgtgcac gccgttctcg tgcaacagtg cggcgaactc cccgaacgtg cggtcggagt
    18841 ggccgacggt gaggaacggc ggcgccatcg cggctagccg tcgccggaca cgcgggtcag
    18901 ggccccgtcc ttgtgcgcgg cgacgtggtc ggtcctgtcg ctcttgatct cgtactgggg
    18961 ctcgtcctcg gaggcgcggc gtgtacggcc cctgaacgcg aagtcgctgg tgtggaccct
    19021 cgtgatcgtg ccggacaccc gtcctgcctc ggagttccag ctgacatggt caccgacgtg
    19081 gaaacggcgt gtcatctcct gcgccctccc tccggtcgtg gtgggacggg tcctcgccta
    19141 ccccggacgg cctcggtgta tgcgggcggg gctcccggcg cccgccggtt cagtcgaagg
    19201 gcgcgagcgt gtccggtgac agcgtcagcg cgcggggcag ggcgtcgaag gcggcggtga
    19261 cctcggcgac gagcgtcgcg gcgtcgccag tgcggtcgct gtgccggtag gcacggaccc
    19321 agttcatgct cccgcagcgc accgcggcca gggccatctc actgaccagc cgcagccgca
    19381 cgtccgcccg gctgtcggcg ccggtctcct cctccagcag ttcggtcagc cgcacccgga
    19441 gggcctggac ggcgccagcg tggtgcgcgt tcagcaccgg attgtgggcg accagcttcc
    19501 gggtggccag gtagcgctcg gtccagtcgt ccggcaggcc gcgcaccgcg tccgcgtagc
    19561 agtcgcgcag gaggggcagg acggggccgg tgacgctcat gcgctccacc tcggcggcgt
    19621 aggcctccca cagttcgccc tcggcggcca gggcgacctc ctccttggag gagtagtagc
    19681 ggaagaaggt gcgcaccgac acctcggccg cggccaccag gtcgtccagc gtggtctggt
    19741 cgaagccccg ctccaggaac atccgaagcg cggtgtcggc gagcactcgc cgcgtgcgca
    19801 gcttcttgcg ttcgcgcagg gggagcgcgg actcctcgtc gtggaagggc tcggcggtca
    19861 tcgggccagg atacggcggt ctctcctggg ccgggaaaaa cccgttgtct gatgtgccag
    19921 tcactggcac tatgccatca ctggcatttt tcggatgcct tcccctccac cgagagagag
    19981 cacatgagcg accggaccgc cgcccccgtc cccgagggac agcgcatcga ggcactgggc
    20041 gaccagctcg tcaagatcca cgacatgctg cggggcgaac tcgcctcgct gcgccgcgac
    20101 ctcgccgggg gaggcgcccc ctccggcgtc ccggcgcccc tggacgagca gctgcgcaag
    20161 aagtgcctgt ccttctgcga cttcctgcac ggccaccaca ccgccgagga cgagggcgtg
    20221 ctgcccggac tggccaggag ccaccccggg ctcgcgcccg tcctggagcg cctgacccgg
    20281 gaacacgtgc tcgtcagccg gtcgctggac cgcatccgcg cgctcctgga gggcggggag
    20341 gcggccgggc tccgcgccga ggtcgagcgc ctggccgccg aggtggaggc gcacctggac
    20401 tacgaggagc gccagatcgt ggaggcgctg aactcctacg gccccgtcac gctctgagaa
    20461 ccgccccgtc gcgcgacgcg gggtcggccg cgtccccgcc gacccgtgcg cgcacccgcg
    20521 gggccggccc cggatcggcc tccgctgaag ccgggtctag tcttcccacc agaacggggc
    20581 gctcacgctc cgcccaggag agggagaccg ctggtgcgga acacggtacg ggtaccccct
    20641 ggctgaggac gaccctgtgg gcgacgcggt ggctgatcgc gctcgtggtc cacttcgcgg
    20701 tcctggtggc cctgctgatg gcgtggggga cggtcttccc gcac
//
