LOCUS       NZ_JAMXJO010000001     21083 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Nocardiopsis dassonvillei strain RACA_4 assembly, whole genome
            shotgun sequence.
ACCESSION   NZ_JAMXJO010000001
VERSION     NZ_JAMXJO010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardiopsis dassonvillei
  ORGANISM  Nocardiopsis dassonvillei
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Nocardiopsaceae; Nocardiopsis.
REFERENCE   1  (bases 1 to 6726007)
  AUTHORS   Elfeky,H.H., Hanora,A. and Solyman,S.M.
  TITLE     Bioactivity of bacteria associated with Red Sea nudibranchs and
            whole genome sequence of Nocardiopsis dassonvillei RACA-4
  JOURNAL   Mar Genomics 67, 101004 (2023)
   PUBMED   36521348
REFERENCE   2  (bases 1 to 6726007)
  AUTHORS   Elfeky,H., Hanora,A.S. and Solyman,S.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2022) Microbiology, Suez Canal University, 4 Km
            Circular Road, Ismailia 41511, Egypt
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Assembly Name                     :: SCU_Nocdas_4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: GCA_900638215.1
            Genome Coverage                   :: 7.6x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024181525.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 06:43:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,838
            CDSs (total)                      :: 5,775
            Genes (coding)                    :: 5,721
            CDSs (with protein)               :: 5,721
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 7 of 54
            Pseudo Genes (incomplete)         :: 51 of 54
            Pseudo Genes (internal stop)      :: 0 of 54
            Pseudo Genes (multiple problems)  :: 4 of 54
            CRISPR Arrays                     :: 12
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:23:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2127117
            Orig. end                         :: 2148200
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAMXJO010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21083
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="8"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21083
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21083
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11083](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11083
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(520..534)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.77"
                     /tool="antismash"
     gene            complement(2715..3851)
                     /gene="carA"
                     /locus_tag="NGM33_RS09120"
                     /old_locus_tag="NGM33_09120"
     CDS             complement(2715..3851)
                     /EC_number="6.3.5.5"
                     /GO_function="GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="carA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249: carbamoyl phosphate synthase small subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017605974.1"
                     /locus_tag="NGM33_RS09120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09120"
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="WP_130398703.1"
                     /transl_table=11
                     /translation="MSESGPAILVLEDGRVFHGRSFGATGETFGEAVFNTGMTGYQETL
                     TDPSYHRQIVVMTAPHIGNTGVNDDDPESGRVWVAGYVVREPARITSNWRAERTLDEEL
                     RRQGVVGIALTGTRALTRHLRDKGVMRAAISTTETDPRALLERVRQQPTMAGADLAAEV
                     STGEPYEVLPPEGVPARFHVAAVDLGIKAMTPQRLAERGCRVTVLPSTATAEEILALDP
                     DGVFFSNGPGDPATADGPVTAMRGVLDAGRPLFGICFGNQILGRALDLGTYKLPFGHRG
                     VNQPVIDTRSGRVAITSQNHGFAVEAPLDEPFDTPYGRAEVSHIGLNDRVVEGLRLLDR
                     PAFSVQFHPEAAAGPHDAAELFDAFVDLMSAQPAPAAK"
     gene            complement(3905..5206)
                     /locus_tag="NGM33_RS09125"
                     /old_locus_tag="NGM33_09125"
     CDS             complement(3905..5206)
                     /EC_number="3.5.2.3"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017565062.1"
                     /locus_tag="NGM33_RS09125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09125"
                     /product="dihydroorotase"
                     /protein_id="WP_130394544.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 7.7e-16, bitscore:
                     56.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDTHGPHLIRGARPLGGDPVDLLLADGRIAATGRDLDAPEGART
                     VDATGLIALPGLVDLHTHLREPGREDAETVATGSRSAAVGGYTAVHAMANTDPVADTAG
                     VVEQVWRLGREAGYCDVRPVGAVTVGLAGERLSEIGAMADSAAGVRVFSDDGICVSDAL
                     LMRRALEYVKAFDGVIAQHAQEPRLTQGAQMNEGSVSDRLGLPGWPAVAEEAIIARDCL
                     LAQHVGSRLHVCHVSTKGSVDIIRWAKARGCDVTAEVTPHHLLLTEELVEGYDPVYKVN
                     PPLRTAEDVQALREGLADGTIDIVATDHAPHPAEAKETEWSTAAMGMVGLETALAVVQR
                     TMVDTGLLTWADVADRMSAAPARIGRVHDHGRDLAVGQPANVVLYDPAAAVDVDGAAMV
                     SKSGNTPFRGMTLPGQVRATFLRGAPTVLEGKIQ"
     misc_feature    5313..5332
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.61"
                     /tool="antismash"
     gene            complement(5374..6282)
                     /locus_tag="NGM33_RS09130"
                     /old_locus_tag="NGM33_09130"
     CDS             complement(5374..6282)
                     /EC_number="2.1.3.2"
                     /GO_function="GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016597 - amino acid binding [Evidence
                     IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014913461.1"
                     /locus_tag="NGM33_RS09130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09130"
                     /product="aspartate carbamoyltransferase catalytic subunit"
                     /protein_id="WP_130394546.1"
                     /transl_table=11
                     /translation="MRHLLSTGDLSRDEATLILDTAAELAQVGDRSVKKLPTLRGRTVV
                     NLFYEDSTRTRTSFELAAKRLSADVINFSAKGSSVSKGESLKDTALTLQAMGADGVVIR
                     HSASGAARRLANWVDGSVLNAGDGTHEHPTQALLDAFTMRSRLGRLEGLRVAVVGDILH
                     SRVARSNVLLLTTLGAHVTLVAPPTLLPVSVHTWPCEVSYDLDDVLPKSDVVMMLRVQA
                     ERMHESFFPSTREYSRNYGLDGERLSRMPEEAIVMHPGPMVRGMEISAEVADSPRCTVT
                     EQVANGVSLRMAVLYLLLGGS"
     gene            complement(6282..6917)
                     /gene="pyrR"
                     /locus_tag="NGM33_RS09135"
                     /old_locus_tag="NGM33_09135"
     CDS             complement(6282..6917)
                     /EC_number="2.4.2.9"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013154122.1"
                     /locus_tag="NGM33_RS09135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09135"
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="WP_130394548.1"
                     /transl_table=11
                     /translation="MRAQKPTTGDAGGGSPAPEVPEGTRAVLDGSEINRALTRIAHEVL
                     ERTKGGRDVTLLGIPSRGVPLAHRLARRIERVEDLTVPAGSLDITMYRDDLRSAPVRAL
                     GRTEIPPGGLDDRVVVLVDDVLFSGRTVRAALDALGDLGRPRAVQLAVLVDRGHRELPI
                     RADYVGKNLPTSLRESVTVRLEETDGHDAVLLGPSRPRTRPGATEGND"
     misc_feature    complement(7034..7049)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    7285..7303
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.1"
                     /tool="antismash"
     gene            7417..7911
                     /locus_tag="NGM33_RS09140"
                     /old_locus_tag="NGM33_09140"
     CDS             7417..7911
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622275.1"
                     /locus_tag="NGM33_RS09140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09140"
                     /product="transcriptional regulator"
                     /protein_id="WP_013154123.1"
                     /transl_table=11
                     /translation="MPSEYAKSLGARLRAIRTQQGLSLHGVEEKSHGRWKAVVVGSYER
                     GDRAVTVQKLAELADFYGVPMSELLPGGAAPTPLGPTPKLVIDLERMQQLPQEKAGPLS
                     RYVATIQSQRGDYNGRVLSIRQEDLRSLAVIYDKSPGDLTEELINWGVLDPEARRAVDA
                     F"
     misc_feature    8118..8132
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.29"
                     /tool="antismash"
     misc_feature    8118..8133
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.93"
                     /tool="antismash"
     misc_feature    complement(8119..8132)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 22.33"
                     /tool="antismash"
     misc_feature    complement(8129..8142)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.67"
                     /tool="antismash"
     gene            8251..8865
                     /locus_tag="NGM33_RS09145"
                     /old_locus_tag="NGM33_09145"
     CDS             8251..8865
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017576792.1"
                     /locus_tag="NGM33_RS09145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09145"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_197044348.1"
                     /transl_table=11
                     /translation="MVADTELRELAPPAFTHAVPALLQVYEAAMRPPPEQLPGRASVMR
                     GHARNPGFRAVVAVRGGLPVGFAYGFHGHGGQWWHDTVAEGLRAGAGIRQARRCLSDAL
                     EVAEVHVHPDAQNRGVGRALLHALCRDRPERTAVLSTRSGPSAARHLYRSCGFTEVLED
                     FRFPGSPGQPFSIMAARLPLTGSGDRRSPGRSAWWPWTGSR"
     gene            complement(8798..9706)
                     /gene="metF"
                     /locus_tag="NGM33_RS09150"
                     /old_locus_tag="NGM33_09150"
     CDS             complement(8798..9706)
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017609704.1"
                     /locus_tag="NGM33_RS09150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09150"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_130398705.1"
                     /transl_table=11
                     /translation="MAPRGPAPRPRHIRELLDAGEPMFSFEFFPPRTPQAQERLWRAIR
                     EIEALGPAFVSVTYGAGGSTRGLTVETTERIATDTTLLPVAHMTLVDHSVAELRHLVGR
                     LADAGVSNMLAVRGDPPGDPDGEWIRHPQGLTYAEELVRLIKDSGDFCVGVAAFPYKHP
                     RSADVETDTDHFVRKCEAGADYAITQMFFDPEDYLRLRDRVAARGCEVPIIPEVFPVVR
                     TSFIPRSEQLSGAPFPADLAEKFASFGDDAESVRAFGIEHAQRMCERLLAEGAPGIHFI
                     TSNRSTATRQIYREISGHRSP"
     gene            10001..11083
                     /locus_tag="NGM33_RS09155"
                     /old_locus_tag="NGM33_09155"
     CDS             10001..11083
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610776.1"
                     /locus_tag="NGM33_RS09155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09155"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_130394550.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3e-45, bitscore:
                     152.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVPSSSPPASAVMAVRSGVDRELTSFCAGHRAQLLEIGQELAPAM
                     DALEAMISGGKRLRPTFCYWGWRGAGGAAEDERVVRAAASLEFLQACALVHDDVIDNSD
                     TRRGLPATHKRLAKLHADQGWSGDSEGFGQGAAILIGDLCLAWSDEMYQASGFPPEVLG
                     RGRPPFDAMRTEVMAGQYLDTLEQVRGTGTREAALRVMRYKSAKYTVERPLHLGAALAG
                     RHEELAGVYTDYGIPLGIAFQLRDDVLGVFGDPSTTGKPAGDDLREGKRTLVVAETLAR
                     AGAADAERFRSLLGAPDLSVASVEWMCSLIEGSGALAVCEEMIAEYADRAVAALESPEL
                     DASAREPLRQLVVAATSRSF"
     gene            11199..12527
                     /locus_tag="NGM33_RS09160"
                     /old_locus_tag="NGM33_09160"
     CDS             11199..12527
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610777.1"
                     /locus_tag="NGM33_RS09160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09160"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_253794426.1"
                     /transl_table=11
                     /translation="MSGHTVSRGPTGTGERALAPDLARGFMLLFIALANTAWYLWALPS
                     SGGGVHPEPGGVLDRIAQFVIVMAVDMRSYPMFAFLFGYGMVQLARRQEAAGSSVREVN
                     ALLRRRNLWLLAFGFVHALLLWMGDVLGAYGLAGLLLGWLFLRRRDATLLVWSGVFTGL
                     AALLAAFSLLGLAFMPADAPSSSAAFSTDLMADSIGDTSILGAALARVLDWPLVTLGQG
                     LLGMVVPAAILLGYWAARRRFLEEPGGHLGPLRWTAALGIGVGWLGGLPLALTQIGVWD
                     LSPAQAAMLTMPHMVTGLACGLGYVALIALAAHRIQGRGRAPGAVVGALSATGKRSLSA
                     YLAQSVLCAPLLSAWGLGLGGELASWSMALFAVGVWLVTVAASYALERAGRRGPAEVLL
                     RRLAYRRPVARGAREAEEPGDASGRTVGRGRVRGAADGERPAP"
     gene            12628..13521
                     /locus_tag="NGM33_RS09165"
                     /old_locus_tag="NGM33_09165"
     CDS             12628..13521
                     /EC_number="1.6.5.2"
                     /GO_function="GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013154128.1"
                     /locus_tag="NGM33_RS09165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09165"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_253794428.1"
                     /transl_table=11
                     /translation="MGDDHTTNHTIGVTGATGALGGRVAARIARLGRPQRLIVRDINRA
                     PEYPGSSAAMAAYEDSTAFERACRGVDTLFLVSATESEDRIDVHVSAVDAAVKAGVSWI
                     VYLSFLRAGPASTFTFARTHFFTEAHIRSTGVRYTFLRPSLYLDLLPDWVDDGGVVRGP
                     AGDGRIAWVSRDDVADVATAVLTDPAAARASHDTSHDVTGPEALSLGATAERLGVLTGR
                     SVRYVPQTLEEALESRRRGGAPDWAVEGWVTSYAAIAAGELDVVSPAVPDLTGHPAQSI
                     EGFLRRHPSALSHVAV"
     misc_feature    complement(13604..13613)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     gene            13672..14676
                     /locus_tag="NGM33_RS09170"
                     /old_locus_tag="NGM33_09170"
     CDS             13672..14676
                     /NRPS_PKS="Domain: PKS_ER (17-331). E-value: 3.8e-29.
                     Score: 93.7. Matches aSDomain:
                     nrpspksdomains_NGM33_RS09170_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017565071.1"
                     /locus_tag="NGM33_RS09170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09170"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_253794430.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.2e-23, bitscore:
                     80.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVQVEEFGGPEVLVVRDVPEPEVGPGQALVEVAAANVMYLDTL
                     VRGGWGLDYFPVAPPYVPGAGVAGRVVRIGPGVDPGWEGAAVVADTGHTDGTPERPTLP
                     VDGYAERAVVPESALVRVPEEVDPRAALALLHDGPTALALERAAGFGPSTTVLVAAAAG
                     GAGTLAVQLARTAGARVIGAARGGAKLALVRELGAQETVDYSEPGWPERVRALTGGAGV
                     DVVLDGAGGALGAAAFGTLADGGRFVGYGSAGGSFTEVDAEEAGRRGIEVLGLFDLKQA
                     DGDRRDALRMVLEMARMGRITPHVGLTLPLERAAEAHAALEGRTVLGKALLVP"
     aSDomain        13723..14664
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NGM33_RS09170_PKS_ER.1"
                     /evalue="3.80E-29"
                     /label="NGM33_RS09170_PKS_ER.1"
                     /locus_tag="NGM33_RS09170"
                     /protein_end="331"
                     /protein_start="17"
                     /score="93.7"
                     /tool="antismash"
                     /translation="RDVPEPEVGPGQALVEVAAANVMYLDTLVRGGWGLDYFPVAPPYV
                     PGAGVAGRVVRIGPGVDPGWEGAAVVADTGHTDGTPERPTLPVDGYAERAVVPESALVR
                     VPEEVDPRAALALLHDGPTALALERAAGFGPSTTVLVAAAAGGAGTLAVQLARTAGARV
                     IGAARGGAKLALVRELGAQETVDYSEPGWPERVRALTGGAGVDVVLDGAGGALGAAAFG
                     TLADGGRFVGYGSAGGSFTEVDAEEAGRRGIEVLGLFDLKQADGDRRDALRMVLEMARM
                     GRITPHVGLTLPLERAAEAHAALEGRTVLGKAL"
     CDS_motif       14131..14190
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NGM33_RS09170_0001"
                     /evalue="1.80E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="NGM33_RS09170"
                     /protein_end="173"
                     /protein_start="153"
                     /score="14.2"
                     /tool="antismash"
                     /translation="TTVLVAAAAGGAGTLAVQLA"
     CDS_motif       14320..14349
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NGM33_RS09170_0002"
                     /evalue="4.30E-03"
                     /label="PKSI-ER_m7"
                     /locus_tag="NGM33_RS09170"
                     /protein_end="226"
                     /protein_start="216"
                     /score="9.9"
                     /tool="antismash"
                     /translation="TGGAGVDVVL"
     gene            complement(14673..15344)
                     /gene="thiE"
                     /locus_tag="NGM33_RS09175"
                     /old_locus_tag="NGM33_09175"
     CDS             complement(14673..15344)
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013154130.1"
                     /locus_tag="NGM33_RS09175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09175"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_130394558.1"
                     /transl_table=11
                     /translation="MRTSHGTSLRKRLDASLLYLCTDARTGRGDLAEFADAALAGGVDI
                     IQLRDKGLEAREEIAALEVMKEACERYGALLAVNDRADIARAVRADVLHLGQRDLPVPM
                     ARDIIGADPVIGRSNNDVAAAAASAEEPGSDYFCVGPTWATPTKPGRPAAGLELVEEAA
                     ALGTDRPWFAIGGIDADNIDRVLDAGARRVVVVRAITEAEDPRAAAAALRQRLAARAAR
                     P"
     gene            complement(15424..15777)
                     /locus_tag="NGM33_RS09180"
                     /old_locus_tag="NGM33_09180"
     CDS             complement(15424..15777)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017565073.1"
                     /locus_tag="NGM33_RS09180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09180"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_019610781.1"
                     /transl_table=11
                     /translation="MTQRDIDTLIGDWLTLKEAAAPLGVSPNRIKTLIRENRMMGVVRD
                     GELSIPAAFIDGDDLVKGLPGTLLLLTDAGFSSEEALRWLFTPDDSLPGTPIQAMRENR
                     GTEVRRRAQSLAF"
     regulatory      15860..15971
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(15928..15941)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            15940..17136
                     /gene="thiO"
                     /locus_tag="NGM33_RS09185"
                     /old_locus_tag="NGM33_09185"
     CDS             15940..17136
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014911304.1"
                     /locus_tag="NGM33_RS09185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09185"
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_156095255.1"
                     /sec_met_domain="DAO (E-value: 6.4e-63, bitscore: 211.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAKGVEATAVRTSNDSHRDRVVVVGGGLVGRVTAWRAAQRGLGV
                     TLVESDPARAASTVAAGMLTPATEAAFGEEPLMELGIRSARMYADFVAELEEASGLDVG
                     HRATGTLLVAFDRDDLAVLTELHALQRRLGIAAERLTGRECRRLEPMLAPSVRGGVLAP
                     DDHSVDPRRLLRALAAAGERAGVTEVRGRAGEVLSPGPGGARLGVRLAGEAEAGRTLPA
                     HQVVLAAGCWGNGVAVPEPVVPPLRPVKGQLLRARVPAGEPPLVSRTVRGLVRGFPTYL
                     VPRADGEVVIGATQEELGHDTSLTVGGLWQVLRDARELVPGVSELEVTETCVGLRPGSP
                     DNEPLLGPTRVPGLHLAAGHFRHGVLLTPVTGEAMARALTDGDLPEYARRFTARRASR"
     misc_feature    17141..17156
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.87"
                     /tool="antismash"
     gene            17142..17348
                     /gene="thiS"
                     /locus_tag="NGM33_RS09190"
                     /old_locus_tag="NGM33_09190"
     CDS             17142..17348
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017565075.1"
                     /locus_tag="NGM33_RS09190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09190"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_130394562.1"
                     /transl_table=11
                     /translation="MELIINGDRREFADDTTVEAVVRDLTGTEAPGGVAVAVNDEVVRR
                     TSWAASPLNQGDRVDVLTAVQGG"
     misc_feature    complement(17143..17157)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.26"
                     /tool="antismash"
     gene            17351..18109
                     /locus_tag="NGM33_RS09195"
                     /old_locus_tag="NGM33_09195"
     CDS             17351..18109
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013154134.1"
                     /locus_tag="NGM33_RS09195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09195"
                     /product="thiazole synthase"
                     /protein_id="WP_253794432.1"
                     /transl_table=11
                     /translation="MNDDLVIAGTSFGSRLITGTGGAPSLEVLEQALIASGTELTTVAM
                     RRVSPGTRGSVWDVLTRNKIRALPNTAGCFTAVDAVRTARLGREALETDWVKLEVVADE
                     HTLLPDPVELLEAAEQLVDEGFTVLPYTNDDPVLARRLEQVGCAAVMPLAAPIGSGLGI
                     RNPHNLELIVEQAGVPVIVDAGIGTASDAALAMELGCDAVLLATAVTRAQDPVRMAAAM
                     RDAVCAGRGARLAGRIPVRRYAQASSPSVS"
     gene            18555..20591
                     /gene="pknB"
                     /locus_tag="NGM33_RS09200"
                     /old_locus_tag="NGM33_09200"
     CDS             18555..20591
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013154135.1"
                     /locus_tag="NGM33_RS09200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_09200"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_130394566.1"
                     /sec_met_domain="Pkinase (E-value: 1e-50, bitscore: 170.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 3e-06, bitscore: 25.7,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDMTTSDPLVGATLDRRYFVESRIAGGGMATVYVAHDLRLDRRLA
                     LKVMHPSLAQDPTFVQRFINEAHSVAKLSHPNVVQVFDQGEDQGHVFLAMEYVPGRTLR
                     DLLKSRGRLGAHDALNAMAPVLAALGAAHQAGMVHRDVKPENVLITEDGRVKVADFGLA
                     RAVEQSNQGLTRTGTLMGTAAYLAPEQIEKGVADARSDVYAAGIMLYELLTGSQPHTGE
                     TPIAIAYQHVNEDVPRPSHFLPGLPAEVDALVTKATERDPRYRPSNAGQYLAKVLAVLN
                     GLPATPPVSAADQAPLTPVAPAAAATASVTAPQLIAGGAGPGTENATMIVDMASAGLDD
                     GRYDDYDRDKDGYGGDDGYDDYRDGPDRRRRNLLIGIGAAVLALVLFGAGWWFLVGQYE
                     NVPDVVGRDPEAASQIIRDEGLRYDLSSEAVYSDAEPGTVGETDPEVGARLSPDDVVTV
                     YLSKGPQTVEMPDLVELDAADALKELEDLGFDPEGIVQEDVNSTEVEPGAVVSTSPEAG
                     AEADREEPVTLTVSRGIPVPPVVGEDLDTARQMLEGEGLSVEVVEEESADVEEGKVIQQ
                     SPDSGSSIGSGGTVTLTVSTGPPGVDIPDVVGMRVNDAREALEEAGFKVKVERVFGGRE
                     VAHQSHTGRAPEDTEITITATPGGIDLGDFGEGGGRGGDDDDD"
     misc_feature    20932..20947
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.84"
                     /tool="antismash"
     misc_feature    complement(20932..20948)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 25.33"
                     /tool="antismash"
     misc_feature    21047..21060
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.89"
                     /tool="antismash"
ORIGIN
        1 cctccttcac cgacaccggg gcgtccacgg gcaggtcgcc gccgtcgccg cgggcgggca
       61 gcatgccctc ctcgcgcagt tcggcgatgg tggccccggc catgacgcgg gcggcggcct
      121 tggccagcgg caccgcggtg gccttggaca cgaacggcac ggtgcgcgag gcgcgcgggt
      181 tggcctccag gacgttgagc acgccggagg cgagcgcgta ctggacgttg atcagaccgc
      241 gcacgcccgt gccgcgggcg atggcctcgg tggagtagcg gatgcgctcg atgtcctcgc
      301 ggcccagggt gatggagggc agggtgcacg ccgagtcgcc ggagtggatc ccggcctcct
      361 cgatgtgctc catgaccccg cccaggtaca ggtcgcggcc gtcgtagagg gcgtcgacgt
      421 cgatctcgat ggcgtcgtcg aggaagcggt cgatgagcac cgggtgctcg gggctgacct
      481 cggcgttgcg ctcgatgtag tcggcgagca tcgtctcgtt gtagacgatc tccatgccgc
      541 ggccgcccag cacgtaggag gggcggacca tgacggggta gccgatctcg tccgcggcgg
      601 ccttggcctc ggcgaaggag taggcggtgc cgtacttggg cgcgggcagc ccggcgtcgg
      661 ccaggacctt gccgaactcg ccgcggtcct cggccaggtc gatcgcctcg gggctggtgc
      721 cgatgatggg caccccggcg tccttgaggc ggcgggccag gccgagcggg gtctggccgc
      781 ccagctggac gatgacgccg acgaccggtc cggcggcctg ctcggcgcgc acgacctcca
      841 gcacgtcctc cagggtgagc ggctcgaagt agagccggtc gctggtgtcg tagtcggtgg
      901 agaccgtctc ggggttgcag ttgaccatca cggtctcgta cccggcgtcg gagagggcga
      961 aggaggcgtg gacgcaggag tagtcgaact ccacgccctg gccgatccgg ttgggccccg
     1021 agcccaggat gatgatcttg gggcggtcgc ccgtggggac ctcggtctcc tcgtcgtagc
     1081 tggagtacag gtagggcgtg ctggcctcga actcggcggc gcaggtgtcc acggtcaggt
     1141 agacggggtg gacgcccagg gcgtggcgca gctcgcggac cacgtcctcg ctgcggccgg
     1201 tgatctggcc gatctggagg tcggagaagc ccagcccctt gacctggcgc agcaggtcgg
     1261 cgtcgagctt gggggcgtcg gccaggacgc gggccgcctc ctccaggcgc agcatctggt
     1321 ccacgaacca ggggtcgatg cgggtggcct cgtggacctc ctcgacggtg gccccggcgc
     1381 gcagggcctg ctggacctgg cgcaggcggt gctcggtggg ggtggcggcc aggcgcagca
     1441 gctcgtcctt gtcgccgggc tcgccctccc aggtcaggcc gacgcccttc ttctccaggg
     1501 agcgcatggc cttctggagg gcctcgggga aggagcggcc gatggccatg gcctcgccca
     1561 ccgacttcat ggtggtggtc aggccggggt cggcgccggg gaacttctcg aaggcgaagc
     1621 ggggcacctt gacgacgacg tagtcgagcg tgggctcgaa gctggccggg gtctcccggg
     1681 tgatgtcgtt ggggatctcg tccagggtgt agccgacggc gagcttggcg gcgatcttgg
     1741 cgatcgggaa gccggtggcc ttggaggcca gcgccgagga gcgcgacacg cgcgggttca
     1801 tctcgatgac gatgacccgg ccggtggtgg ggtggacggc gaactggatg ttgcagccgc
     1861 cggtgtccac gccgacctcg cggatgacgg cgatgccgat gtcgcgcagc ttctggtact
     1921 cgcggtcggt gagggtcatg gcgggggcga cggtgatgga gtcgccggtg tgcacgccca
     1981 tggggtcgag gttctcgatg gagcagacga ccacgacgtt gtcgttggtg tcgcgcatca
     2041 gctccagctc gtactccttc cagccgagga tggactcctc caggagcacc tcggtggtcg
     2101 gggagagcgc caggccctgc ccggcgatgc ggcgcagttc ggcctcgtcg tgggcgaagc
     2161 ccgagcccgc gccgcccatg gtgaaggagg ggcgcacgac gacggggtag gagagctcct
     2221 cggccgcggc caggcactcc tccagggtgt ggcagatgcg cgagcgggcg gactcgccgc
     2281 cgatgcgctc gacgatgccc ttgaagctct cgcggtcctc accggactgg atggcctcga
     2341 tgttggcgcc gatgagctcg acgccgtact tggcgaggac gcccgcctcg tccagggcga
     2401 cggcggcgtt gagggcggtc tgcccgccca gggtgggcag gagcgcgtcg gggcgctcct
     2461 tggcgatgat cttctcgatc atctcggtgg tgatcggctc cacgtaggtg gcgtcggcga
     2521 tctccgggtc ggtcatgatc gtggccgggt tggagttgac caggatgacc cgcaggccct
     2581 cggcccgcag aacccggcag gcctgggtgc ccgagtagtc gaactcggcc gcctgcccga
     2641 tcacgatcgg gccggagccg atcacgagga cggatgaaag gtcactacgg cgcggcatgc
     2701 tctgcttcct cttgctactt ggcagccgga gcgggctggg cggacatcag gtcgacgaac
     2761 gcgtcgaaga gttcggcggc gtcgtggggg ccggcggcgg cctccgggtg gaactggacg
     2821 ctgaacgcgg ggcggtccag cagccgcagg ccctcgacga cgcggtcgtt gaggccgatg
     2881 tggctgacct cggcccggcc gtagggggtg tcgaagggct cgtcgagggg ggcctcgacg
     2941 gcgaagccgt ggttctggct ggtgatggcg accctgccgg agcgggtgtc gatcaccggc
     3001 tggttgacgc cccggtgccc gaagggcagc ttgtaggtgc ccaggtccag ggcgcggccc
     3061 aggatctggt tgccgaagca gatgccgaag agcggcctgc ccgcgtccag gactccgcgc
     3121 atggcggtga cgggtccgtc ggcggtggcg gggtcgccgg ggccgttgct gaagaacacc
     3181 ccgtccgggt ccagggcgag gatctcctcc gcggtggcgg tggagggcag cacggtgacc
     3241 cggcaccccc gctcggccag gcgctggggg gtcatggcct tgatgcccag gtccacggcg
     3301 gcgacgtgga agcgggcggg cacgccctcg ggcggcagga cctcgtaggg ctcgccggtg
     3361 ctgacctcgg cggccaggtc ggccccggcc atggtgggct gctggcgcac gcgctccagc
     3421 agggcccgcg ggtcggtctc ggtggtgctg atggcggcgc gcatgacgcc cttgtcgcgc
     3481 aggtggcggg tgagggcgcg ggtgccggtg agggcgatgc cgaccacgcc ctggcggcgc
     3541 agctcctcgt ccagggtgcg ctcggcccgc cagttggagg tgatgcgggc gggctcgcgc
     3601 acgacgtacc cggcgaccca gacgcggccg gactcggggt cgtcgtcgtt gacgccggtg
     3661 ttgccgatgt ggggggcggt catcaccacg atctggcggt ggtacgaggg gtcggtgagg
     3721 gtctcctggt agccggtcat gccggtgttg aagaccgcct cgccgaaggt ctccccggtg
     3781 gcgccgaagg agcggccgtg gaagacacgg ccgtcctcga gtaccagaat cgcgggtccg
     3841 ctctcggaca cgttcgcccc ctcctccgcc gggccgcggg cggcccgggt gttctgttct
     3901 gtgctcactg gatcttcccc tccaggacgg tcggggcgcc gcgcaggaac gtggcgcgca
     3961 cctggccggg cagggtcatg ccccggaagg gggtgttgcc gctcttgctg accatggccg
     4021 cgccgtccac gtcgacggcg gcggccgggt cgtacaggac cacgttggcg ggctggccga
     4081 ccgccaggtc acgcccgtgg tcgtggaccc ggccgatgcg ggccggtgcc gcggacatgc
     4141 ggtcggcgac gtcggcccag gtcagaagac cggtgtcgac catcgtgcgc tgcacgaccg
     4201 ccaacgccgt ctccaggccg accattccca tggcggcggt ggaccactcg gtctccttgg
     4261 cctccgcggg gtggggggcg tggtcggtgg cgacgatgtc gatggtgccg tcggccaggc
     4321 cctcgcgcag cgcctggacg tcctcggcgg tgcgcagggg cgggttgacc ttgtagacgg
     4381 gatcgtagcc ctccaccagc tcctcggtca gcaggaggtg gtggggtgtg acctcggcgg
     4441 tgacgtcgca gccgcgggcc ttggcccagc ggatgatgtc gaccgagccc ttggtcgaga
     4501 cgtggcacac gtgcaggcgc gagcccacgt gctgggcgag caggcagtcg cgggcgatga
     4561 tcgcctcctc ggcgaccgcg ggccagccgg gcaggccgag gcggtcggag acggagccct
     4621 cgttcatctg ggcgccctgg gtcaggcgcg gctcctgggc gtgctgggcg atgacgccgt
     4681 cgaatgcctt gacgtactcc agggcgcggc gcatgagcag ggcgtcggag acgcagatgc
     4741 cgtcgtcgga gaagacgcgc acgcccgcgg cggagtcggc catggcgccg atctcggaga
     4801 ggcgctcccc ggccaggccg acggtgacgg cgccgacggg gcgcacgtcg cagtacccgg
     4861 cctcgcggcc caggcgccag acctgttcga cgaccccggc ggtgtcggcg acggggtcgg
     4921 tgttggccat ggcgtggacg gcggtgtagc cgcccacggc ggcggatcgg gagccggtgg
     4981 cgaccgtctc ggcgtcctcg cggccgggct cgcgcaggtg ggtgtgcagg tccaccagac
     5041 cgggcagggc gatcaggccg gtggcgtcga cggtccgggc gccctcgggg gcgtccaggt
     5101 cccggccggt cgcggcgatc cggccgtcgg ccaggagcag gtcgacgggg tcgccgccga
     5161 gggggcgggc gccgcggatc aggtgcggtc cgtgggtgtc gggcatcgcg gtgttggctt
     5221 cctcgtgttc tgggatgggg aggggcggcg cggggccccg gggcgcgccg gcgggccggg
     5281 cgcggcgggg gccggggccg cccgggcccg tggcggggcc tcgcgtccct cgggtgcggt
     5341 ggcgcggggc acaggggccc cgcggccggg ctgtcaggag ccgccgagca gcaggtagag
     5401 cacggccatg cgcaggctga cgccgttggc gacctgctcg gtgacggtgc agcggggcga
     5461 gtcggcgacc tcggcggaga tctccatgcc gcggaccatc gggccggggt gcatgacgat
     5521 cgcctcctcg ggcatgcggg acaggcgctc gccgtccagg ccgtagttac ggctgtactc
     5581 gcgcgtggac gggaagaacg actcgtgcat gcgctcggcc tgtacccgca gcatcatgac
     5641 gacgtcggac ttgggcagga cgtcgtcgag gtcgtaggag acctcgcacg gccaggtgtg
     5701 caccgagacc ggcagcaggg tgggcggcgc gaccagggtg acgtgcgcgc ccagggtggt
     5761 gagcagcagc acgttggagc gggcgacccg gctgtgcagg atgtcgccga cgacggccac
     5821 ccgcagcccc tccaggcgcc ccaggcgcga gcgcatggtg aaggcgtcca gcagggcctg
     5881 ggtggggtgt tcgtgggtgc cgtcgcccgc gttgaggacg gacccgtcca cccagttggc
     5941 gaggcggcgg gcggcgccgg aggcgctgtg ccggatgacg acgccgtcgg cgcccatggc
     6001 ctggagggtc agcgcggtgt ccttgaggct ctcgcccttg gagacgctgg agcccttggc
     6061 cgagaagttg atgacgtccg cggacaggcg cttggcggcc agctcgaagg aggtgcgggt
     6121 gcgggtggag tcctcgtaga agaggttgac cacggtgcgc ccgcgcaggg tgggcagctt
     6181 cttgacggag cggtcgccga cctgggcgag ttcggcggcg gtgtccagga tgagggtggc
     6241 ctcgtcgcgg gagaggtcgc cggtggagag caggtggcgc atcagtcgtt cccctcggtg
     6301 gcgccggggc gggtgcgggg gcgggacggg ccgagcagca ccgcgtcgtg tccgtcggtc
     6361 tcctccaggc gcacggtgac gctctcgcgc agcgaggtgg gcaggttctt gcccacgtag
     6421 tcggcgcgga tgggcagctc gcggtggcct cggtcgacca ggacggcgag ctggacggcg
     6481 cgggggcgcc ccaggtcgcc gagggcgtcc agggcggcgc ggacggtgcg gccggagaag
     6541 aggacgtcgt cgacgaggac gacgacgcgg tcgtcgagcc cgcccggggg gatctcggtc
     6601 cggccgaggg cgcggacggg ggcggagcgc aggtcgtcgc ggtacatggt gatgtcgagc
     6661 gagcccgcgg ggacggtgag gtcctccacc cgttcgatgc gccgtgccag gcggtgggcg
     6721 agcgggaccc cgcgcgaggg gatgcccagg agggtgacgt cccggccccc cttggtgcgt
     6781 tcgagcacct cgtgggcgat gcgggtcagc gcccggttga tctcgctgcc gtcgaggacg
     6841 gcgcgggtgc cctcgggcac ctcgggtgcg ggggaaccgc caccggcgtc accggtcgtc
     6901 ggtttttgcg cacgcaaagt agtgactccc ttccctgcct cactgaacag gtcgttaaag
     6961 gatgtcgatc ggatccacgc taccagcgac gttcgcgacc cccgtgaggc ggccgatgac
     7021 ccgaggtcac taatgtgact ctggtcacac cgcaagcgca cgcgtacccc ctgaaatgtg
     7081 gtcatgtcat cacccagtgg atacggcaac gaaggggccg aaacctgaaa tacccaggag
     7141 gaacgggctt ttcgtgccat cgtgacgcac gactcctccc gctcggtccc gacatgagag
     7201 gtgtctcact tacgcacggt ttggccaccg attagtcgcg tttcacacca acggcttgac
     7261 ctggaaggca gaccccccta ccgtcactgt ctgtaaccac tgccgggtgg ggttgcaacc
     7321 cgtgaccatc cgctggaccg cccaggcggc ccgccgagta cgagcggacg tccccccacc
     7381 acgccagcca ctgtcacggc cgggagcgac aagaagatgc catccgaata cgcgaagtcc
     7441 ctcggtgcgc gactgcgtgc catccgcacc cagcagggcc tgtccctgca cggggtggaa
     7501 gagaagtccc acggccgctg gaaggccgtc gtggtgggct cctacgagcg cggcgaccgc
     7561 gccgtcaccg tccagaagct cgccgagctg gcggacttct acggcgtgcc gatgtcggag
     7621 ctgctgccgg gcggcgcggc tcccaccccg ctgggcccca cgcccaagct ggtcatcgac
     7681 ctggagcgca tgcagcagct gccgcaggag aaggccgggc cgctgtcccg ctacgtcgcc
     7741 acgatccaga gccagcgggg tgactacaac gggcgggtgc tctccatccg ccaggaggac
     7801 ctgcgctcac tcgcggtcat ctacgacaag tcgcccgggg acctgaccga ggagctcatc
     7861 aactggggcg tcctcgaccc cgaggcgcgc cgcgcggtcg acgccttctg accggtaccc
     7921 ggacaccggg acgaccgaac agatccgcac ccgctcgacg agaaccggcg accccacggg
     7981 ggcgccggtt ctcgtcgtgt ccgcccggcc ggggactggc cggcggacgg ggcggagcgg
     8041 cgcggccgga cgtggggctt cccctcccca acccgaccgc gccgccctcc cgccggaggg
     8101 gggtccgacg gagcgcgtcg aactcatgtt cgacacgatc cagttaaccc caggccgccg
     8161 gacccgtcaa ggaccccgcc cggcggtgcg cgcaccccgt cctcgcgcga atcccgggac
     8221 tcggcggggc cggggaacta cccttggccc gtggtagccg ataccgagtt gcgcgagctg
     8281 gccccgcccg ccttcacgca cgccgtcccc gcgctgctcc aggtgtacga ggccgccatg
     8341 cggccgcccc cggagcagtt gcccgggcgc gcctccgtca tgaggggcca cgcccgcaac
     8401 ccgggctttc gcgcggtggt ggccgtgcgc ggcggccttc cggtcggctt cgcctacggc
     8461 ttccacgggc acggcggcca gtggtggcac gacacggtgg cggaggggct gcgcgcgggc
     8521 gcggggatcc gccaggcgcg ccgctgcctg tccgacgcgc tggaggtcgc cgaggtgcac
     8581 gtccacccgg acgcacagaa ccggggcgtg ggccgcgccc tgctccacgc cctgtgccgg
     8641 gacaggccgg agcgcaccgc ggtgctgtcc acgcgttcgg gaccctccgc ggcgcgccac
     8701 ctgtaccgct cgtgcgggtt caccgaggtg ctggaggact tccgcttccc cggcagcccc
     8761 ggtcagccct tctcgatcat ggccgcccgg ctccccctca cgggctccgg tgaccggaga
     8821 tctcccggta gatctgcctg gtggccgtgg accggttcga ggtgatgaag tggatgcccg
     8881 gcgcgccctc ggccagcagc cgctcgcaca tgcgctgggc gtgctcgatg ccgaaggccc
     8941 gcacggactc ggcgtcgtcg ccgaaggagg cgaacttctc ggccaggtcg gccgggaagg
     9001 gagcgccgga gagctgctcc gagcgcggga tgaacgaggt gcgcaccacc gggaagacct
     9061 cggggatgat cggcacctcg cagccgcgcg cggccacccg gtcgcgcagg cgcaggtagt
     9121 cctcggggtc gaagaacatc tgggtgatgg cgtagtcggc gcccgcctcg cacttgcgca
     9181 cgaagtggtc ggtgtcggtc tcgacgtcgg ccgagcgcgg gtgcttgtag gggaaggcgg
     9241 ccacgcccac gcagaagtcg ccgctgtcct tgatcaggcg caccagctcc tcggcgtagg
     9301 tcagcccctg ggggtggcgg atccactccc cgtccgggtc gccgggcggg tccccccgca
     9361 cggcgagcat gttggacacg cccgcgtcgg cgaggcggcc gacgaggtgg cgcagctcgg
     9421 cgacggagtg gtcgaccagg gtcatgtgcg cgaccggcag cagtgtggtg tcggtcgcga
     9481 tgcgctcggt ggtctccacg gtcagcccgc gcgtgctgcc gcccgcgccg taggtgaccg
     9541 agacgaaggc ggggccgagg gcctcgatct ccctgatcgc gcgccacagg cgctcctgcg
     9601 cctggggcgt gcggggcggg aagaactcga aggagaacat cggctcgccc gcgtcgagga
     9661 gttcgcggat gtgacgcggc ctgggggccg ggcctcgggg cgccacaggg agtgtcggtg
     9721 cagccagcat gcgcaccagc ttaggtcaga cacccccgcg gcggaggccc cgtcccatcc
     9781 tgtgagaccc gtggcgcacg ccactcccga acgccgctcc cgagcggtgc gacgtgcggg
     9841 gacgcggctc ggccccgcac ccgccgcggt gccccgcgcg tccgcgcgtc cgcgcgggcg
     9901 gcgccggtga cggtgccgtc cgtgtcggcg gccggctgga agcggcccga cggggcggag
     9961 cgggaccggg ccgcgcccga cagccgataa tctgcgggtc atggtgcctt cctcttcccc
    10021 gcccgcctcc gccgtcatgg cggtccgctc cggtgtggac cgcgaactga cctcgttctg
    10081 cgccggccac cgggcccagc tgctggagat cgggcaggag ctggccccgg ccatggacgc
    10141 gctggaggcg atgatctccg gcggcaagcg cctgcggccg accttctgct actggggctg
    10201 gcggggcgcg ggcggcgcgg ccgaggacga gcgggtggtg cgggccgcgg cctccctgga
    10261 gttcctccag gcgtgcgcgc tcgtccacga cgacgtgatc gacaacagcg acacccggcg
    10321 cggtctgccc gccacgcaca agcggctggc caagctgcac gccgaccagg ggtggagcgg
    10381 cgacagcgag ggcttcggcc agggcgcggc catcctcatc ggcgacctgt gcctggcctg
    10441 gtcggacgag atgtaccagg ccagcggctt tccgccggag gtgctgggcc gggggcggcc
    10501 ccccttcgac gcgatgcgca ccgaggtcat ggccgggcag tacctggaca ccctggagca
    10561 ggtgcggggc accggcacac gcgaggcggc gctgcgcgtg atgcgctaca agtccgccaa
    10621 gtacacggtg gagcgcccgc tgcacctggg cgcggccctg gcgggccgcc acgaggagct
    10681 ggccggggtc tacaccgact acggcatccc gctggggatc gccttccagc tgcgcgacga
    10741 cgtgctgggc gtgttcggcg acccgtccac cacgggcaag cccgccgggg acgacctgcg
    10801 cgagggcaag cggacgctgg tcgtggccga gaccctggcg cgcgccgggg cggccgacgc
    10861 cgagcggttc cgctcgctgc tgggggcgcc ggacctgtcg gtggcctcgg tggagtggat
    10921 gtgctccctg atcgagggct cgggcgcgct ggccgtgtgc gaggagatga tcgcggagta
    10981 cgccgaccgg gccgtcgcgg ccctggagag ccccgagctg gacgcgtccg cccgcgagcc
    11041 gctgcgccag ctggtcgtgg ccgccacctc gcgctccttc tgagggtcct tccctagggg
    11101 actttcccgg gtccgcgccc accgggggcc tgttgtgtcc gcctgcccgc tccggttgaa
    11161 tcactaacac gacatatcgc gaaaccgggg agtctcccat gtctggacac accgtttccc
    11221 gcggtccgac cggcacgggg gagagagccc tcgcaccgga cctggcgcgc gggttcatgc
    11281 tcctgttcat cgcgctcgcg aacacggcct ggtacctgtg ggcgctcccg tccagcgggg
    11341 gcggcgtcca ccccgagccg ggcggcgtgc tggaccggat cgcgcagttc gtcatcgtca
    11401 tggcggtgga catgcgcagc tatccgatgt tcgccttcct gttcgggtac ggcatggtgc
    11461 agctggcccg gcgccaggag gcggcgggct cctccgtgcg ggaggtgaac gcgctgctgc
    11521 gccgccgcaa cctgtggctg ctcgcgttcg gcttcgtcca cgccctgctg ctgtggatgg
    11581 gcgacgtcct gggcgcctac ggcctggcag ggctgctcct gggctggctg ttcctgcggc
    11641 gcagggacgc cacgctgctg gtgtggtcgg gcgtgttcac cgggctggcc gccctgctgg
    11701 cggcgttcag cctgctgggc ctggccttca tgcccgcgga cgccccctcc tcctcggccg
    11761 cgttcagcac ggacctgatg gccgacagca tcggcgacac ctcgatcctg ggcgccgcgc
    11821 tggcccgcgt cctggactgg ccgctggtca cgctgggcca ggggctgctg ggcatggtcg
    11881 tgcccgcggc gatcctgctc ggctactggg ccgcgcgccg ccggttcctg gaggagccgg
    11941 gcgggcatct gggcccgctg cgctggaccg cggccctggg catcggcgtg gggtggctgg
    12001 gcgggctgcc cctggccctg acccagatcg gggtctggga cctgtccccc gcgcaggcgg
    12061 ccatgctgac catgccgcac atggtgaccg ggctggcctg cggcctgggc tacgtggcgc
    12121 tgatcgcgct ggcggcgcac cggatccagg ggcgcggtcg cgcaccgggc gcggtggtcg
    12181 gcgcgctgtc ggcgaccggc aagcgctcgc tgtcggccta cctggcccag tcggtgctgt
    12241 gcgcacccct cctgtcggcc tggggcctgg ggctgggcgg cgaactcgcc tcgtggtcga
    12301 tggccctgtt cgcggtgggc gtgtggctgg tgacggtggc ggcctcctac gccctggagc
    12361 gcgcgggcag gcgcggaccg gccgaggtgc tgctgcgccg cctggcctac cgccgcccgg
    12421 tcgcgcgggg cgcccgggag gcggaggagc ccggcgacgc gtcgggtcgc acggtcgggc
    12481 gcggacgggt gcggggagcg gcggacggcg agcgtcccgc gccctgacct cggcgtcccg
    12541 gggcgccgac cgcgcccgcc cccgtggcgc aaaaaggcgc gtgccgctca gcgtccggca
    12601 cgccctcgta acgcaggatg gggtgtcatg ggcgacgatc acacgacaaa ccacaccata
    12661 ggggtcacgg gggcgaccgg ggcgctgggc gggcgggtcg ccgcgcggat cgcgcggctg
    12721 ggcaggcccc agcggctcat cgtacgcgac atcaaccgcg ctcccgagta ccccggcagc
    12781 agcgcggcga tggcggccta cgaggactcc acggccttcg agcgggcctg ccggggggtg
    12841 gacacgctgt tcctggtctc ggccaccgag tccgaggacc ggatcgacgt ccacgtgagc
    12901 gcggtggacg cggcggtcaa ggcgggggtg tcctggatcg tctacctgtc cttcctgcgc
    12961 gcgggcccgg cgtccacctt cacgttcgcg cgcacgcact tcttcaccga ggcgcacatc
    13021 cggtccacgg gggtgcggta caccttcctc agacccagcc tgtacctgga cctgctgccc
    13081 gactgggtgg acgacggggg cgtggtgcgg ggcccggccg gtgacggccg gatcgcgtgg
    13141 gtctcgcgcg acgacgtggc ggacgtggcc accgccgtgc tgaccgaccc cgcggccgcg
    13201 cgcgcctcac acgacaccag ccacgacgtc accggcccgg aggcgctgtc cctgggcgcg
    13261 acggcggaga ggctgggcgt gctcaccgga cgctcggtgc gctacgtgcc ccagaccctg
    13321 gaggaggcgc tggagtcgcg ccgccgcggc ggcgcccccg actgggcggt cgagggctgg
    13381 gtgacctcct acgccgcgat cgccgccggg gaactcgacg tggtctcgcc cgccgtcccc
    13441 gacctgaccg gccatcccgc ccagtccatc gagggcttcc tgcggcgcca tcccagcgcg
    13501 ctgtcgcacg tcgcggtctg acctcggccc ccgccctgcg cgccgtgccc ccgtgcgggg
    13561 tgctccctgt gccgtggatc cctccgacgc ccggcccttg acctcaacaa atattgaggt
    13621 aagaggctgg gcggtgtcgg aagcaggcgg tgcgcaccga gggagaacgg catgcgagcg
    13681 gtacaggtcg aggagttcgg cggcccggag gtcctggtgg tccgggacgt gcccgagccc
    13741 gaggtgggac cgggccaggc tctggtggag gtcgccgcgg cgaacgtgat gtacctggac
    13801 accctggtcc gcggcggctg ggggctggac tacttccccg tggctccccc ctacgtcccc
    13861 ggcgcgggcg tggccgggcg ggtggtccgg atcggcccgg gcgtggaccc gggctgggag
    13921 ggggccgcgg tggtcgccga caccgggcac acggacggga cgccggaaag gcccaccctg
    13981 cccgtggacg gctacgccga acgggccgtg gtcccggagt cggcactggt cagggtgccc
    14041 gaggaggtgg acccccgggc ggcgctggcc ctgctgcacg acggaccgac cgcgctggcg
    14101 ctggagcggg cggcgggctt cgggcccagc accacggtcc tggtcgccgc ggccgccgga
    14161 ggggcgggca ccctcgccgt ccaactggcc cgcacggccg gggcccgggt catcggcgcg
    14221 gccaggggcg gtgccaagct ggccctggtc cgcgaactgg gcgcgcagga gaccgtggac
    14281 tactccgagc cgggctggcc ggagcgggtg cgcgcgctga ccggcggcgc cggggtcgac
    14341 gtggtcctgg acggcgccgg gggcgcgctg ggcgcggcgg ccttcgggac cctggccgac
    14401 ggcggccggt tcgtcggcta cggctccgcg ggcgggagct tcacggaggt ggacgcggag
    14461 gaggccgggc gccgcgggat cgaggtcctg ggcctgttcg acctcaagca ggccgacggc
    14521 gaccggcggg acgccctgcg gatggtgctg gagatggccc gcatgggcag gatcaccccg
    14581 cacgtggggc tgaccctgcc gctggagcgg gccgcagagg cgcacgccgc gctagagggg
    14641 cgcacggtgc tcggcaaggc cctgctggtg ccctagggcc gggcggcgcg ggccgccagg
    14701 cgctggcgca gagcggcggc ggcggcccgg gggtcctccg cctccgtgat cgcgcgcacg
    14761 accacgaccc ggcgggcccc ggcgtccagc acgcggtcga tgttgtcggc gtcgatcccg
    14821 ccgatggcga accaggggcg gtcggtgccc agcgcggccg cctcctccac cagctccagc
    14881 ccggcggccg ggcggcccgg cttggtgggg gtcgcccagg tcggtccgac gcagaagtag
    14941 tcgctgccgg gctcctcggc ggaggcggcc gcggcggcga cgtcgttgtt ggagcggccg
    15001 atcacggggt cggcaccgat gatgtcgcgg gccatgggca cgggcaggtc ccgctggccc
    15061 aggtggagga cgtcggcgcg cacggcgcgg gcgatgtcgg cgcggtcgtt gaccgcgagc
    15121 agggcgccgt accgctcgca cgcctccttc atcacctcca gggccgcgat ctcctcgcgt
    15181 gcctccaggc ccttgtcccg gagctggatg atgtccactc ccccggccag ggccgcgtcg
    15241 gcgaactcgg ccaggtcgcc ccgaccggtc cgggcgtcgg tgcacaggta cagaagcgat
    15301 gcgtccaggc gcttgcgcag gctggttccg tggctggtcc tcacacggtc caccctaggc
    15361 cctggcgcgt tcggacccaa gggggaggga cgcggcggcg cgcccctccc ccttccgcgc
    15421 ggactagaag gccaggctct gggcccggcg gcgcacctcg gtgccccggt tctcgcgcat
    15481 ggcctggatc ggcgtgcccg gcagggagtc gtcgggggtg aacagccagc gcagggcctc
    15541 ctcggaggag aagcccgcgt cggtgagcag cagcagcgtc cccggcagac ccttgaccag
    15601 gtcgtcgccg tcgatgaagg cggcgggaat ggagagttcg ccgtcgcgga ccacacccat
    15661 catgcggttc tcgcggatca gcgtcttgat ccggttcggg ctcacgccca gcggagcggc
    15721 ggcctccttg agggtcagcc agtcgccgat gagcgtgtcg atgtcgcgtt gtgtcacacc
    15781 accaatctgc cacatccgcg cacctccttc cccccggcac ggcgcgcgcc gaccacgggt
    15841 cctagaatgg ggacagaccc ctacatcccg cgggagccgg gtgggacccg gctgagaggg
    15901 aggctgtgag cctccgaccg cacgaacctg atccggatca tgccggcgaa gggagtggaa
    15961 gccacagccg tgcgcacctc caacgattcc caccgcgacc gcgtcgtcgt ggtcggcggc
    16021 ggcctcgtcg gccgggtcac cgcctggcgc gccgcccaac gcggactggg cgtcaccctg
    16081 gtcgagtccg accccgcccg cgccgcctcc accgtggccg cgggcatgct gacccccgcc
    16141 accgaggcgg cgttcggcga ggagcccctc atggagctgg gtatccgctc ggcccgcatg
    16201 tacgcggact tcgtcgccga actggaggag gccagcggcc tggacgtcgg acaccgcgcc
    16261 accggcacgc tgctggtcgc cttcgaccgc gacgacctgg ccgtcctcac cgaactgcac
    16321 gcgctccagc ggaggctggg catcgccgcc gagcgcctca ccggccgcga gtgccgccgc
    16381 ctggagccca tgctcgcccc gtccgtgcgc ggcggcgtcc tggcccccga cgaccactcc
    16441 gtggacccgc ggcggctgct gcgcgccctg gccgcggcgg gagagcgcgc gggcgtcacc
    16501 gaggtccgcg ggcgggccgg ggaggtcctc tcccccggcc ccgggggcgc gcggctgggc
    16561 gtgcgcctgg ccggggaggc cgaggcgggg cggaccctgc ccgcgcacca ggtggtgctg
    16621 gccgcgggtt gctggggcaa cggcgtcgcg gtccccgaac ccgtcgtccc gccgctgcgc
    16681 ccggtcaagg ggcagctgct gcgcgcccgg gtgcccgccg gcgagccgcc gctcgtcagc
    16741 cggaccgtcc gcggcctggt ccggggcttc ccgacctacc tggtgccgcg cgccgacggc
    16801 gaggtcgtca tcggcgccac ccaggaggag ctgggccacg acacctcgct caccgtcggg
    16861 gggctctggc aggtgctgag ggacgcgcgc gaactcgtcc ccggggtgag cgagctggag
    16921 gtcaccgaga cctgcgtcgg gctgcgcccc ggctcccccg acaacgaacc cctcctgggg
    16981 cccacccggg tcccgggact gcacctggcc gccgggcact tccggcacgg ggtcctgttg
    17041 accccggtga ccggggaggc catggcccgg gccctgaccg acggagacct gcccgagtac
    17101 gcccgccgtt tcacggcacg acgcgcaagt aggtagtagc agtggaactg atcatcaacg
    17161 gcgaccgccg cgagttcgcc gacgacacga ccgtggaagc cgtcgtgcgc gacctgaccg
    17221 gcaccgaggc ccccggcggt gtcgccgtgg ccgtcaacga cgaggtggtg cgccggacct
    17281 cgtgggccgc gagcccgctc aaccagggcg accgcgtgga cgtcctcacc gcggtgcagg
    17341 gaggctgagc atgaacgacg acctcgtgat cgcgggaacc tccttcgggt cccggctgat
    17401 caccggaacc ggcggagcgc cctccctgga ggtcctggag caggccctga tcgcctccgg
    17461 caccgaactg accaccgtgg cgatgcgccg tgtctccccc ggcacccggg ggtcggtgtg
    17521 ggacgtcctg acccgcaaca agatccgggc gctgcccaac accgccgggt gcttcaccgc
    17581 cgtggacgcg gtgcgcaccg cccgcctggg ccgcgaggcg ctggagaccg actgggtcaa
    17641 gctggaggtg gtggcggacg agcacacgct gctgcccgac cccgtcgagc tgctggaggc
    17701 cgccgaacag ctggtggacg agggcttcac cgtgctgccc tacaccaacg acgaccccgt
    17761 gctggcccgg cgcctggagc aggtgggctg cgccgcggtg atgcccctgg ccgccccgat
    17821 cggctcgggg ctgggcatcc gcaacccgca caacctggag ctgatcgtcg agcaggccgg
    17881 cgtgcccgtc atcgtggacg cggggatcgg caccgccagc gacgccgccc tggccatgga
    17941 gctggggtgc gacgcggtcc tgctggccac ggccgtgacc cgcgcccagg acccggtgcg
    18001 catggccgcc gcgatgcgcg acgccgtatg cgcgggccgc ggcgcgcgcc tggcgggccg
    18061 catccccgtg cggcgctacg cccaggcctc ctcgccgtcc gtgagttagg ccacccggcc
    18121 ccgcgctccg tccccggccc gccgccgacc ggtgcgtccc acctggggag tttggcggcg
    18181 tcctctaccg tggaacgagt gtgcggtccg gcaagggcgc atcccgcaca ccacgaccac
    18241 ccaggcgcga gcgtccccac cgcccacgga gcgggcctca ccggggacgg ggcgacccga
    18301 cgaccggcgg agcacacgcc accgggaccg ggagagcccc ggccggggtc gggacccgtc
    18361 gtccggggag accgagcagg cccccccgga cgacccaccg gccccaccgg cacccgaacg
    18421 ggacggcgcg accgcgaacc gcggggcaga cctggcgtgg gcttccgcta tcgtgtcggt
    18481 tcgacacccg gtgtcgggta cgcgccaccg gccgcgacag cccgcgctcc ccgcagcaag
    18541 gacactactc cgccgtggac atgacgactt ccgacccgct cgtaggcgcc accctggacc
    18601 gacgttactt cgtggagtcc aggatcgccg gaggcgggat ggcgaccgtc tacgtcgccc
    18661 acgacctgag gttggaccga cggctggccc tgaaggtgat gcacccttcg ctggcccagg
    18721 acccgacctt cgtgcagcgc ttcatcaacg aggcgcactc cgtcgccaag ctctcccacc
    18781 ccaacgtcgt gcaggtcttc gaccagggtg aggaccaggg gcacgtgttc ctggccatgg
    18841 agtacgtacc cgggcgcacc ctgcgcgacc tgctcaagtc ccggggcagg ctcggcgccc
    18901 acgacgccct gaacgccatg gccccggtgc tggccgcgct cggcgccgcc caccaggcgg
    18961 gcatggtgca ccgcgacgtc aagcccgaga acgtcctcat caccgaggac ggccgggtca
    19021 aggtcgccga cttcggcctg gcgcgcgccg tggagcagtc caaccagggg ctgacccgca
    19081 cgggcaccct catgggcacg gcggcctacc tggcccccga gcagatcgag aagggcgtcg
    19141 ccgacgcccg cagcgacgtg tacgcggcgg gcatcatgct ctacgagctg ctcaccggca
    19201 gccagccgca caccggcgag acgcccatcg cgatcgccta ccagcacgtc aacgaggacg
    19261 tcccgcgccc ctcgcacttc ctgcccggcc tgcccgcgga ggtcgacgcg ctggtcacca
    19321 aggccaccga gcgcgacccc aggtaccgtc ccagcaacgc gggccagtac ctggccaagg
    19381 tcctggcggt gctcaacggc ctgcccgcga ctcctcccgt ctcggccgcc gaccaggccc
    19441 cgctgacgcc cgtcgccccg gcggcggcgg ccacggcctc ggtgaccgcg ccccagctca
    19501 tcgccggggg cgccggtccg ggcaccgaga acgcgaccat gatcgtggac atggcctccg
    19561 ccggcctcga cgacggccgc tacgacgact acgaccgcga caaggacggg tacggcggcg
    19621 acgacgggta cgacgactac cgggacggcc ccgaccggcg ccgccgcaac ctgctgatcg
    19681 ggatcggcgc ggcggtcctg gcgctcgtcc tgttcggcgc gggctggtgg ttcctggttg
    19741 gccagtacga gaacgtcccc gacgtggtgg gccgcgatcc cgaggccgcg agccagatca
    19801 tccgcgacga gggcctgcgc tacgacctgt cctccgaggc cgtctacagc gacgccgagc
    19861 cgggcacggt cggcgagacc gacccggagg tgggcgcccg cctgtccccc gacgacgtgg
    19921 tcaccgtgta cctgtccaag ggcccgcaga cggtggagat gcccgacctg gtcgagttgg
    19981 acgccgccga cgcgctcaag gagctggagg atctgggctt cgacccggag ggcatcgtcc
    20041 aggaggacgt gaactccacc gaggtcgagc ccggcgcggt ggtctccacc tcccccgagg
    20101 cgggcgcgga ggccgaccgg gaggagccgg tcaccctcac cgtcagccgg ggcatcccgg
    20161 tgcccccggt ggtcggcgag gacctggaca ccgcccgcca gatgctggag ggcgagggcc
    20221 tgtccgtcga ggtggtcgag gaggagagcg cggacgtcga ggagggcaag gtcatccagc
    20281 agagccccga cagcggctcc agcatcggct ccggcggcac cgtcaccctg accgtctcca
    20341 ccggtccgcc cggcgtggac atccccgacg tggtcggcat gcgggtcaac gacgcgcgtg
    20401 aggcgctgga ggaggccggt ttcaaggtca aggtcgagcg cgtcttcggc ggccgcgagg
    20461 tggcgcacca gtcgcacacc ggcagggcgc ccgaggacac cgagatcacg atcaccgcga
    20521 ctccgggcgg catcgacctg ggcgacttcg gcgagggcgg cggccgcggc ggcgacgacg
    20581 atgacgactg accggcacgg gcgcgcggcc tgagccggag gcgagggggc gggaccgatc
    20641 ggtcccgccc cctcgccgtg tgcggccgac ccggccaggc gcacggcccg ccgcccgctc
    20701 caccgccccg gccgtcggcc cgtgtcgtgg gcgccgcccg cccgggatag ggtcacccgc
    20761 atggcgagcg aggcgatccg ggtactggtg gtggacgacc accccatgtg gcgcgacgcg
    20821 gtctcacacc ccacgtgacc agcaacgatg caacgaagcc gcccgtttca agttggtacc
    20881 caccaccgta actccgggtg gtaccagagt ccagggggca gctactgcta cacaccctag
    20941 aggggtacat agaaccctgg ggcggtatat ctataccagt atctagatac tcctgggggt
    21001 agcagtacct agggtcctgg gggtactacc cgcacccatc gttggatatt gatacaaaga
    21061 ttgatacaca acacaagaca tcc
//
