LOCUS       NZ_JAMXJO010000001     25454 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Nocardiopsis dassonvillei strain RACA_4 assembly, whole genome
            shotgun sequence.
ACCESSION   NZ_JAMXJO010000001
VERSION     NZ_JAMXJO010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardiopsis dassonvillei
  ORGANISM  Nocardiopsis dassonvillei
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Nocardiopsaceae; Nocardiopsis.
REFERENCE   1  (bases 1 to 6726007)
  AUTHORS   Elfeky,H.H., Hanora,A. and Solyman,S.M.
  TITLE     Bioactivity of bacteria associated with Red Sea nudibranchs and
            whole genome sequence of Nocardiopsis dassonvillei RACA-4
  JOURNAL   Mar Genomics 67, 101004 (2023)
   PUBMED   36521348
REFERENCE   2  (bases 1 to 6726007)
  AUTHORS   Elfeky,H., Hanora,A.S. and Solyman,S.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2022) Microbiology, Suez Canal University, 4 Km
            Circular Road, Ismailia 41511, Egypt
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Assembly Name                     :: SCU_Nocdas_4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: GCA_900638215.1
            Genome Coverage                   :: 7.6x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024181525.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 06:43:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,838
            CDSs (total)                      :: 5,775
            Genes (coding)                    :: 5,721
            CDSs (with protein)               :: 5,721
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 7 of 54
            Pseudo Genes (incomplete)         :: 51 of 54
            Pseudo Genes (internal stop)      :: 0 of 54
            Pseudo Genes (multiple problems)  :: 4 of 54
            CRISPR Arrays                     :: 12
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:23:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1563231
            Orig. end                         :: 1588685
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAMXJO010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25454
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="7"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25454
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25454
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15454](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15454
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(334..1296)
                     /locus_tag="NGM33_RS06775"
                     /old_locus_tag="NGM33_06775"
     CDS             complement(334..1296)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017576927.1"
                     /locus_tag="NGM33_RS06775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06775"
                     /product="PrgI family protein"
                     /protein_id="WP_253794028.1"
                     /transl_table=11
                     /translation="MASDEVSAWRGRIPADIDRPEPVLFNLTARQCLIITPVLAGAWGA
                     YLLLREAVPLWLFVMALAPVLGTAIALALGERDGRGLEQVAASALAWARAPKHLVPAPS
                     GHVPALPRWAPRLRRGPRLAPLRLPASAISPEGVVDLDGRCAVMIACTTLPFQLASGRE
                     QDQVLAAFAGVLDALAEPVQILVQRRSADLGEFTAMLRDNASRLPHPALAEAATAHADF
                     LDELTATHELSHQQVLVVVTATGTARKAGPALLRRAADTADRLAALGIRTQVLDADEAA
                     DVLRASMTAPGTRITDPAPIGCELAGTGATDGHEHEEER"
     gene            complement(1330..3339)
                     /locus_tag="NGM33_RS06780"
                     /old_locus_tag="NGM33_06780"
     CDS             complement(1330..3339)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NGM33_RS06780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NGM33_06780"
                     /product="hypothetical protein"
                     /protein_id="WP_253794030.1"
                     /transl_table=11
                     /translation="MSPAPWGRGPASPEPPPSDDPLPEPEDPGTQPEPEPEPEEVPAPE
                     PEITDDPLPPPQDEREDEPPLREQSEVPVEVDADEDVFDCGLVDPGCHVSNWFADFVVS
                     GLNPALGWLAEKAFHTPEPTEGMQALHGGILATSNTLFVLLIVAGGIVAMGYQTVQSRY
                     SAADVLPRAVFAFVASNFSLWAAREMIRASNQISAAIGAQGIDAREAAQNLRDRMEVIL
                     EEALVFTILLLVVVVVLLVVWMVTEAVRICMAIVLTIAAPMLLIFHALPQTNRIAELWW
                     KSMAGLCAIPIAQSIVFIAMARLFFEGQMTIFGSLHQTAAAPEPDPGLVLDTGLGSETS
                     VVLASSVLASPSDVDAGDAGWLMNIMLLLVLLYVQIRIGSWVMKLVWQPNPGTSPIAAI
                     LKNIAWMMAFRSVSSMRLPSVPASSLKWQFFSPRTPGRTLPRYTPKPASGLQPLQPQGW
                     WYRARHDPPEVAGALSPGGRRALPGPGHGHSNPGPGGPRPAVGPVGGPSGETSGPPWSG
                     GRARGPLALPGPRALPPVPPPRTAPPAALRRELEVGHMPGSPRTGQQALFPRPAPPPGR
                     SAPSAPPERRWRQGILPTPPPVRVPDRRAVQRLGLPDPAPRPSAGLRHLPDMPPLAWGK
                     PPHVKGQRALFPNPKRVWKQYGLFPPPRTNRNEQ"
     gene            complement(3336..3662)
                     /locus_tag="NGM33_RS06785"
                     /old_locus_tag="NGM33_06785"
     CDS             complement(3336..3662)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017576929.1"
                     /locus_tag="NGM33_RS06785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06785"
                     /product="hypothetical protein"
                     /protein_id="WP_253794032.1"
                     /transl_table=11
                     /translation="MWWVAAGDDAVWVWAAEATAESAEEETAELRQVVNRIRMVIIALA
                     SALGTLFLTIAAVRWLAANGEVGAIDGAKRALTGTAVGYGIAILATVLMDIVEWIVSVG
                     GAGE"
     gene            complement(3824..4660)
                     /locus_tag="NGM33_RS06790"
                     /old_locus_tag="NGM33_06790"
     CDS             complement(3824..4660)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017576930.1"
                     /locus_tag="NGM33_RS06790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06790"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_253794034.1"
                     /transl_table=11
                     /translation="MAFASSPLAVVETGFVRLSPTHLTLRGTDVHPWLQNRTYSLYELR
                     GVLMDEGTPHDVRDAVWRHTIRAARLSQDWMVGALGLCLPALRSTARRTCRGLTADGVD
                     TVESAIVSEVVHQVRTINLDYARLVWYLTRPAHRAALSARRHEQEAPIPTGDPGRQEDP
                     DPGVQASPDLLLLSAVRVGVLSRAEARLIARTRLENVPLAEEAAELGASYKAVAKRRER
                     AEARLLEAVRAGEVVIADALVHGKDLPEQRSGLRLLVTSAKKRSKPMSHRPLPRAS"
     misc_feature    4739..4754
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.76"
                     /tool="antismash"
     misc_feature    4957..4966
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.42"
                     /tool="antismash"
     misc_feature    4958..4971
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.96"
                     /tool="antismash"
     misc_feature    4959..4973
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.13"
                     /tool="antismash"
     misc_feature    complement(4992..5006)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.09"
                     /tool="antismash"
     gene            complement(5178..5366)
                     /locus_tag="NGM33_RS06795"
                     /old_locus_tag="NGM33_06795"
     CDS             complement(5178..5366)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573288.1"
                     /locus_tag="NGM33_RS06795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06795"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_372497199.1"
                     /transl_table=11
                     /translation="MIDLTSGWHKSSYSGAQGECVEVNETAVAEAVLVRDTQNRDLGCL
                     SFPGGEWSAFLGAAFSR"
     gene            complement(5363..6172)
                     /locus_tag="NGM33_RS06800"
                     /old_locus_tag="NGM33_06800"
     CDS             complement(5363..6172)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.4"
                     /locus_tag="NGM33_RS06800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06800"
                     /product="DUF5753 domain-containing protein"
                     /protein_id="WP_253794036.1"
                     /transl_table=11
                     /translation="MPEKTLSSWITFGRELRRLRDRRGLTLDQVAEATGYGASTISKYE
                     NAYRAPKRDFLNEAEALFSTNGDLLRRWTEAKRAEEDPDWHRKIVTAEEQASGIQIWNP
                     ALVPGMFQTPDYARQIFRDGRPLDTSEEIDRLVDLRVSRLDALRGMNNPRLVAILAETV
                     VRARVGSSAVMKEQLGHLLDLDSAGVVRILILPADTPYYGGASGPFRLLSFKERETLVE
                     VEHASGGELLGGDTVTRLLAVYGELQTWALPPVASHDVISRAMGGLE"
     gene            6171..6956
                     /locus_tag="NGM33_RS06805"
                     /old_locus_tag="NGM33_06805"
     CDS             6171..6956
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.5"
                     /locus_tag="NGM33_RS06805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06805"
                     /product="ATP-binding protein"
                     /protein_id="WP_253797466.1"
                     /transl_table=11
                     /translation="MGRTLQKLSTFLYGFHQIAADARKGIEAEHLALDDGHHGGKRRPQ
                     ETPATAPPAPGTAPTEHSRGENVANPTESEIPTSTSRTRPQEGGVRFPGERTNVFQRAD
                     EVRPAPEVVLSAGEAVVAAAHSRKAQAAARRSFPGIPDSVAHVRDWVEQTCAQWQAPVP
                     EVLTLVASELTSNAIAHTHSGLPGGQFATRLLLYPDRMRLEVRDAGPLSGRTPLRRTPA
                     LTAEHGRGLVLVDALATGWGRLPAGTGTFAELTRVPGEE"
     misc_feature    6183..6185
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6957..7172
                     /locus_tag="NGM33_RS06810"
                     /old_locus_tag="NGM33_06810"
     CDS             6957..7172
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NGM33_RS06810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NGM33_06810"
                     /product="hypothetical protein"
                     /protein_id="WP_253794038.1"
                     /transl_table=11
                     /translation="MRLPRRTRSRPLVVRAPAGFDDARWRAAQQGYVLTRQKRLLGAVY
                     ALTSLDGDTAILHGLGEVRAFLDRPS"
     gene            7470..7685
                     /locus_tag="NGM33_RS06815"
                     /old_locus_tag="NGM33_06815"
     CDS             7470..7685
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013156434.1"
                     /locus_tag="NGM33_RS06815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06815"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_253794040.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDYRYLLDGRPDVLTPGEVAQLFNIRPRSLHRGEWDNVLRPFRT
                     PGGARRYPKEHIAALLNQPDDSAPAP"
     gene            7743..7886
                     /locus_tag="NGM33_RS06820"
                     /old_locus_tag="NGM33_06820"
     CDS             7743..7886
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NGM33_RS06820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NGM33_06820"
                     /product="hypothetical protein"
                     /protein_id="WP_253794042.1"
                     /transl_table=11
                     /translation="MEIDEPLPEATVYEAAVVYLHAYTRLERRDGAVRIAAPTSPPTCA
                     NS"
     gene            8110..8304
                     /locus_tag="NGM33_RS06825"
                     /old_locus_tag="NGM33_06825"
     CDS             8110..8304
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573283.1"
                     /locus_tag="NGM33_RS06825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06825"
                     /product="hypothetical protein"
                     /protein_id="WP_047867932.1"
                     /transl_table=11
                     /translation="MKFEKLSGDCNRDDCPGIYSTDNGTVVVQGALLTDTTGLTPSPGE
                     AAVEIPTHLIEEAARALGR"
     gene            8288..8812
                     /locus_tag="NGM33_RS06830"
                     /old_locus_tag="NGM33_06830"
     CDS             8288..8812
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573282.1"
                     /locus_tag="NGM33_RS06830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06830"
                     /product="DUF6879 family protein"
                     /protein_id="WP_253794044.1"
                     /transl_table=11
                     /translation="MRLEGDAWREFFDSFQHEAFRLETLPSYTVPEEEEELRRFLAGET
                     RPAEELHTDSYLLRVRNHVESGRRIRRVHTLTSPVGDHLRFQFEWGYAFSVQAGEEVNI
                     LDFATTPDPGLPRQDFWLFDDTRVVLMHYAADGTQTGRELLEGADSAPYVAYKNLALEH
                     AVPFTEYYKAD"
     gene            8813..9670
                     /locus_tag="NGM33_RS06835"
                     /old_locus_tag="NGM33_06835"
     CDS             8813..9670
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610920.1"
                     /locus_tag="NGM33_RS06835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06835"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_253794046.1"
                     /transl_table=11
                     /translation="MTLEPDRAQQPRSELAEALRSLRRASGLTGARLAVRSGMSQAKVS
                     KIENGRVLPSALDVERILRALDVPPGEDEAARLLELARVANTDYQGFRTALQRGLGETQ
                     RDLAAIEASASTIRFFLPCMITGLLQTPDYARQTLSHTLVNRGASWETALARRLERQTV
                     LYDEGKRFVFVLTEAALRWPLCRPEAMAVQMDRIASLSELPSVDIRVVPADPPVPSGPL
                     NGFTVYDDRLVTVEVFTGKLALRDPKDVAYSMEIFAFFHDHALEGENTRPFLRGLAQEY
                     RNRA"
     gene            9782..9940
                     /locus_tag="NGM33_RS06840"
                     /old_locus_tag="NGM33_06840"
     CDS             9782..9940
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573280.1"
                     /locus_tag="NGM33_RS06840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06840"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_253794048.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 3.5e-15, bitscore:
                     54.0, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNTQDSPSSESPFALDIRLIENSDSLAQLINLTDDGCGSSCPNS
                     CTTSAAD"
     CDS_motif       9782..9868
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MQNTQDSPSSESPFALDIRLIENSDSLAQ"
                     /locus_tag="NGM33_RS06840_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9869..9940
                     /prepeptide="core"
                     /locus_tag="NGM33_RS06840_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-3.30"
                     /molecular_weight="2119.2"
                     /monoisotopic_mass="2117.9"
                     /core_sequence="LINLTDDGCGSSCPNSCTTSAAD"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MQNTQDSPSSESPFALDIRLIENSDSLAQ"
                     /leader_location="[9781:9868](+)"
                     /alternative_weights="2137.3"
                     /alternative_weights="2155.3"
                     /alternative_weights="2173.3"
                     /alternative_weights="2191.3"
     gene            10001..12199
                     /locus_tag="NGM33_RS06845"
                     /old_locus_tag="NGM33_06845"
     CDS             10001..12199
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="NGM33_RS06845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06845"
                     /product="lantibiotic dehydratase family protein"
                     /protein_id="WP_253794049.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.1e-174,
                     bitscore: 580.5, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.4e-18,
                     bitscore: 65.7, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSGEERHVGWRVVGRPLVRASLLSGLPTSGVPDLSGSDPHPWLK
                     WLRRVWEHPGLTEAIRNASPDLAAGVEALLDQDPAAVRVRRARKATASVLRYVLRADSR
                     ATPFGLFAGVTAATFSERSRVVWGGAHRRVVSPGGAWVAEVVGALEAPPVVREHLLVVV
                     NNTVVEERGHLVVPQYARPAPGAPGSDAEQVEVRVNSAVRLVLETAREPVSWSTLRAKL
                     AAEYPDEPAVSTDAMLARLVQVRALLTSLAPASTETDSLGCLVSSLAQHNTCAPPETRP
                     LMSLLQKAHTAMEEHNCGGRSSTLGKADEAVSRVSRVQPLGVDVRVDADMALPVAVARA
                     AEQAAHMLTVLSPYPDGLPAWHTYRERFADRYGDALVPVREVVHPQTGLGFPAGYATAD
                     AEGRAESLTSRDRWLLEQAQAAALDRRREISADALLDELAARQSALPPGHTELNLRVES
                     PSRAALDSGRFRVAVLGASRSAATMAGRFAALAGVRGDLREAVSRTTSAGAVPVQLSFP
                     PLRARSSHLVRSERLLDHLISVGEYPASVPGQLGVDDLAVGCDDGGLFLFSRILARRVE
                     PVVPHALNLRYAPPMARFLAELPRAGRAVVIGFDWGAASSLPFLPRVRSGNMVLVNARW
                     RVRANDLPPRTASWPRWRQAWSTWAERRNLPGVVDLGKGDQRLRLDLSEPAHLFLLRAQ
                     LDKEGGTVLTEAPDPRSSGWCEGRPTEVLVQLCRKEAA"
     aSDomain        10478..10762
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_NGM33_RS06845_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="7.10E-21"
                     /identifier="RREFam001.1"
                     /label="NGM33_RS06845"
                     /locus_tag="NGM33_RS06845"
                     /protein_end="254"
                     /protein_start="159"
                     /score="65.7"
                     /tool="antismash"
                     /translation="LVVVNNTVVEERGHLVVPQYARPAPGAPGSDAEQVEVRVNSAVRL
                     VLETAREPVSWSTLRAKLAAEYPDEPAVSTDAMLARLVQVRALLTSLAPA"
     gene            12196..13437
                     /locus_tag="NGM33_RS06850"
                     /old_locus_tag="NGM33_06850"
     CDS             12196..13437
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610917.1"
                     /locus_tag="NGM33_RS06850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06850"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_253794058.1"
                     /sec_met_domain="LANC_like (E-value: 7.9e-43, bitscore:
                     144.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTTTTEATEIAGLVADRLATPEQGRALAGERWWPQSLAHGAAGV
                     ALLHIERARTGHGPWDRVQRWLECAVAEGADSSPSAHLYYGAPAVAFVLHRAATVHPGY
                     EHELARLDRAVERIVLSRLERAHARMDAGGLPLLSEFDTIRGLTGLGSLLLARDPQGPL
                     LRDLLAYLVRLTEPVTVHGRTLPGWWSPVGPGGKKNAAFPGGHANTGMAHGIAGPLTLL
                     AAALRRGITVEGHTEAIERILVWLDTWEQTSPAGAWWPYWVTRAQLDGTCGLVGPQRPS
                     WCYGAAGVARAQLLATDALGDQQRYATAQSTLARLFTEEPPMALDSSLCHGRAGLAVLA
                     HATALGNAPGLCAALSDGDAAAVANGLLAGSGIGLLEGAAGIAIALHTLHNPTPDLGWA
                     AFLLLDHQEHHADG"
     gene            13430..15454
                     /gene="fxlM"
                     /locus_tag="NGM33_RS06855"
                     /old_locus_tag="NGM33_06855"
     CDS             13430..15454
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573276.1"
                     /locus_tag="NGM33_RS06855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06855"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_253794059.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.4e-29, bitscore:
                     101.2, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 4e-50, bitscore: 168.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDEQPQILIQWVDWAAAEHWGVHGLGPALEGARKEGLIPAWWFV
                     RKKPHWRLRYTGGRPARQFLDTELERLHAEGAVTRWVHGIYEPETGAFGGPAGMALAHA
                     VFGEDSRHLLAYLGHRSTMSGTELGRRELALLLGSSFLRGARLDWFEQADVWAKVAALR
                     ALPQPFSAEEELVSSARTLMTLSPRPLIDSGPLRHTSAWAQVFTAAGAALTDLAAQGRL
                     NRGLRAVCAHHLIFAFNRWGLPYRDQHILSTTARKAAMTDTNHRATPESAQALREELIR
                     QLRKDGVLTTPAVEGAFRAVPRHAFVPNATLEEAYTNAPVHIKHDDNGASISCGSQPGV
                     VATMLEQAALEPGMRVLELGAGTGYNAALLGHLVGPTGSVTTIDVDQDLVEGACARLKE
                     NGATNVTVVLGDGALGHPDGAPFDRIIATVGCHDVPRAWVDQLAPGGRLIAPVRIAGDV
                     SRSIVFEARGDHWASVDSQLCTFMPLRGGVGDDPRRILALDGDGTVMLQANQDQSIAPE
                     QVDHVLIEPSATTWTGVNFGKGQPLDPMWLWLSTRLDNRVSRMPVQPQAVASDLVSPGL
                     PWGDMASVPAGERGLAYLTMRPVAGQQGRHEVGVIGHAHTGQKLAEQMAEHIRAWEPHR
                     AEELSFALHYNAVPEPSTVTRRVLARAHSTLVVSWGEPV"
     gene            15451..16536
                     /locus_tag="NGM33_RS06860"
                     /old_locus_tag="NGM33_06860"
     CDS             15451..16536
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610915.1"
                     /locus_tag="NGM33_RS06860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06860"
                     /product="hypothetical protein"
                     /protein_id="WP_253794061.1"
                     /transl_table=11
                     /translation="MRFAHWFPLIPRPRPPADSLAARVERLAAAGRTARSGSDEEALAA
                     AAQVYNGAALLASDVGLPELARDWCWEHAHAYLTHLPLNATMAQRALEPVVNLARLRIR
                     AGHGAEAFTMLTALQEGVRAATATVIDRYKLPLDQLTVSDEDRGELHRWLWTVYMGDGM
                     RALASEERWQEAAKQARQHGGIGSRLFDGRQVTVIAEMMSDNPASALAMIEGSVAREPW
                     EKAVQAVLALWCLKESGETTVDDAEMALDRVRDVESRQVVFTTRLGIVATKLTGGFRGG
                     TPALLSQLVSDVVQAQDGYAARDLLNAWKQELPQDQVDALGSVLKASGIDTKALPQASL
                     HALRATLEEANRSLRDGCIPA"
     misc_feature    16387..16389
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16453..16455
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            <16570..>16999
                     /locus_tag="NGM33_RS06865"
                     /old_locus_tag="NGM33_06865"
                     /pseudo=""
     CDS             16570..>16999
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558177.1"
                     /locus_tag="NGM33_RS06865"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="NGM33_06865"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPGCSWEKANCLFGVTRATAHRWFQTWTEMGLWPTIHRTVLDELG
                     RRALLDWSRATVDSQSIRAKRGGEHGAKPH"
     misc_feature    17172..17187
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.88"
                     /tool="antismash"
     gene            17277..19283
                     /locus_tag="NGM33_RS06870"
                     /old_locus_tag="NGM33_06870"
     CDS             17277..19283
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017535661.1"
                     /locus_tag="NGM33_RS06870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06870"
                     /product="class I SAM-dependent DNA methyltransferase"
                     /protein_id="WP_253794063.1"
                     /transl_table=11
                     /translation="MSVLSSLVWSVADTLRGPYAEAEYGPIILPFTVLRRLECVMAPHR
                     EVMAEIVAQYSGEQQRRTHLKLNTRTQDSAGLSFWTTSNYTLKRALQDPNNLAENLIDY
                     VGGFSANLDVFKSFDFETVIRTLDTRDRLAQVARHFEKIDLSPDAVSNADMGDLFENLI
                     YRFAESANKGAGQFYTPRDVVRLLIDLVYAEDTEALRDRGTVRSIYDPTVGTGGMLTVA
                     DEHLHELNPDASTGLFGQEINPHTYAICKADLLIKGQDPSNVRQGDTLVVDRFENQGFD
                     YVLSNPPFGTDWKAVESAVKNEHARGGQGRFAPGLPAVGDAAMLFLLHVASKMRDVDST
                     GRGGKAGIVLNGSPLFNGVAGSGPSDIRGHMLENDLVEAIVALPNDMFYNTGIATYLWI
                     LSNAKPSERKGTVQLIDAKGLGSKMRKSIGLKRIEISEAHRKDIVRAFVGNEVEPDKAT
                     VPVKVFANRDFAYWTVTVERPMQFRFECTPETIGAVAEHKKLGQIAGLTEALESFGEQP
                     YLNREKFLKELDGHLRDHGIGLTTAQRKSLWQTIGVHDKTADICLHTSGMRKGEVEPDP
                     ALRDTENIPFGWGGHPKTHEALKQTVQAYFDTEVKPHVDNAWIDWSKTKTGYEIPFARH
                     FYTYEPPRPLEEIDTDLERVVGEIMTLLREVES"
     gene            19448..20566
                     /locus_tag="NGM33_RS06875"
                     /old_locus_tag="NGM33_06875"
     CDS             19448..20566
                     /EC_number="3.1.21.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013579.5"
                     /locus_tag="NGM33_RS06875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06875"
                     /product="restriction endonuclease subunit S"
                     /protein_id="WP_253794065.1"
                     /transl_table=11
                     /translation="MDVYKNDSIVDSLDFMTASATREQIKKFRIRVGDTLITKDSETAD
                     DIGIAAFVEYEADDLVCGYHLAIVRPDLRRVLPKYLYWVLNSEPIARQWGVTAAGVTRV
                     GIRSTELNKVTMPLPPLDEQQAIAEYLDHETAQTDALVAKQEEFIGLLRERRSRKREVL
                     ATRVANGQRLRWVLSEVDKRAGARGGDLPLMSVSINWGVRRRDETTDRLARAEDLSHYK
                     ICLAGDVIVNRMRAFQGALGVAPEDGVVSPDYAVLRATPEADPYWLAELMRTKAFVGEI
                     ILRLRGIGGTDSGNVRTPRINTVDLLDIRADVPEVTTQRAELQNLLIGNHRIDSLIAKA
                     EEHIALAKERRSALVTAAVTGQIDVRAARKAS"
     gene            20572..23805
                     /locus_tag="NGM33_RS06880"
                     /old_locus_tag="NGM33_06880"
     CDS             20572..23805
                     /EC_number="3.1.21.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017535663.1"
                     /locus_tag="NGM33_RS06880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06880"
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="WP_253794067.1"
                     /transl_table=11
                     /translation="MAAPDGTHEKAFEIEIAEYLTAHGWEYSETDDGYDVERAIWPEDV
                     HWWLSETQPDEYAKVVRVGTAAEAADREALLASLVTRLDTPMSSGGGTLNVLRRKFSHT
                     RGATAHLRMCQFKPATTLNRDVSRQYRKVRMRVVRQVHFSPKRNDSRSIDLVFFVNGLP
                     VATCELKSFFKQEWRTAVSQYRNDRNPAGQPLLGFGTRALVHFAVDDDQVHITTKLAGE
                     KTYFLPFNRGNEDTGAAGNPPNPNGAATSYLWEQVLQRDNWLAILGSQMFLKIETDEDP
                     VTGKIKRSTTLMFPRYHQWRAVNKLVDTITEEGPGRRYLIEHSAGSGKTNTIAWTAHRL
                     ARLHNQSNEKVFDKVLIVSDRRILDAQLQQAVEQVDDTVGTVAVIDSAAVRRSGGSKSR
                     ALLDALTGSALIVVVTIQTFPYVKGLLETTLGDQSFAVIVDEAHTSQSGKTAADLKKVL
                     TEGGQVTDEDELDSQDIINQVVEADVAREQQIAAETAARARARNISLLAFTATPKAKTK
                     TLFGRDNDEGKPVSFDVYPMRQAIEEGFILDVLRGYQTYRTAFEIEQRGEHGVVASIAE
                     GEGADDGSDRLVDPKIASRKIMRFANLHPTNVGQKVEIIVEHFRANVAHLLDGHAKAMV
                     VTDSRQAAVRYKIETDKYLAQKRYGYQTIVAFSGKIGDDVYGLTDATEASMNPNLGSDL
                     AREFRRPEYQLMLVADKFQTGFDQPLLCAMYVDKRLPDVHAVQTLSRLNRIYRAPSGEV
                     KDRTFVLDFVNDPEEIREAFLTYYLEAHVETATDPNLVHRLATKLAQARIYTSVEVERY
                     AEAWWAPTQSHAALAAAVTPARDEFVNRWADATGRHDGQALDELRTFRKDCGSYVRLYD
                     FMSQVVDYGTSDLEKLAEFLRQLVRLLAVDEPSADVDVSGLELRRVRQINQGKADIGLS
                     GDQDTPSLAGISGVGTGLSRQDPQQELLSNVVARINALFGSEFADPQIEGFVVAAAGMA
                     EEDSRIADQIDHNALDQFMASPQLRETLTDAAVLNEGAFGKLTGALTGESDRADEFIRL
                     IGAYLYQSRRLRTVNAADPEDADASDEPQ"
     misc_feature    23383..23385
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            23963..24142
                     /locus_tag="NGM33_RS06885"
                     /old_locus_tag="NGM33_06885"
     CDS             23963..24142
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NGM33_RS06885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="NGM33_06885"
                     /product="hypothetical protein"
                     /protein_id="WP_253794069.1"
                     /transl_table=11
                     /translation="MNRSPEEPWTINDLRSAYERYAEIVNTSDLAPSTKTTYLVHADRF
                     VRWMAGEISIRGEQ"
     gene            24139..24753
                     /locus_tag="NGM33_RS06890"
                     /old_locus_tag="NGM33_06890"
     CDS             24139..24753
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013964.5"
                     /locus_tag="NGM33_RS06890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06890"
                     /product="HNH endonuclease"
                     /protein_id="WP_253794071.1"
                     /transl_table=11
                     /translation="MTFEHSDRSTPSGRTSGTHIVITTDTDDCYHTGEECTAFRANHTA
                     NEAQAKGRRRTVRITVADAEEFGRRLCTVCGAQERANAEQPKFLRELLADLSPAEKRRR
                     QAWIRRERTRANGPVERFTTREIGDRDRWLCGLCHDPVDPSCKARDPRSPSVDHIRAVS
                     LGGTQTRDNVRITHLGCNHERNNSTELLDLEDARRVQEIID"
     misc_feature    24706..24708
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(25067..25081)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            25147..25449
                     /locus_tag="NGM33_RS06895"
                     /old_locus_tag="NGM33_06895"
     CDS             25147..25449
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017610001.1"
                     /locus_tag="NGM33_RS06895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NGM33_06895"
                     /product="hypothetical protein"
                     /protein_id="WP_130397942.1"
                     /transl_table=11
                     /translation="MSPVQIVRTVAAALIAGGGTLGLVPGGPCGAGWWAPSGGDGAHYG
                     WFALGEEPPNMLAGVCNTAMAPVGSWAIALIVAGVTLLAGVWITTSYRPKDKPRT"
ORIGIN
        1 cggcgtccat ggccgccgtc acctggtgcg ggtcctgcac ccgcccctgg gacgtgctgg
       61 tgcggtgggc cgattccagg cgggtccggc gtttgcgcag ctgtgcggcg gcgctggggg
      121 cgggcacggg ttccaggtgg aaggagatgt cgagctgccc gggataggtg agcaggggct
      181 cggcccatcc ggcggtgacc tcgcgggggt agccggtgac ggcgagggtc tggcacacgc
      241 tgccctcgac ctccaggtga cgcgagccca ggcggatggc cggagcgccc agcgcgtgcg
      301 tttcgggtcg cgtcctcgaa cttcggagat ccatcagcgt tcctcctcgt gctcgtgtcc
      361 gtcggtggcg ccggtgcctg cgagctcgca gccgatcggc gcggggtcgg tgatgcgggt
      421 gcccggggcg gtcatcgacg cccgcaggac gtctgcggct tcgtctgcgt ccaggacctg
      481 ggtgcggata ccgagggcgg ccaggcggtc cgcggtgtcg gcggccctgc gtagcagagc
      541 aggacccgcc ttgcgggcgg taccggtcgc ggtcaccacc accagcacct gctggtggga
      601 cagctcgtgt gtggcggtca gctcgtccag gaagtcggcg tgcgccgtgg cggcctcagc
      661 cagtgccggg tgcggaaggc gggaggcgtt gtcgcgcagc atcgcggtga actcgcccag
      721 gtcggcgctg cgccgctgga cgaggatctg caccggttcg gccagggcgt ccagcactcc
      781 ggcgaaggcg gccagcacct ggtcctgttc acgtcccgag gcgagctgga agggcaaggt
      841 ggtgcaggcg atcatgaccg cgcaccggcc gtccaggtcg accactcctt ccggagagat
      901 cgctgaggcc ggaagccgca gcggtgccaa ccgtgggccg cgccgcagac ggggcgccca
      961 ccgaggcagc gcggggacgt gccctgaagg tgcggggacc agatgcttgg gtgcgcgcgc
     1021 ccaggccagg gcactggccg cgacctgctc cagaccccgg ccgtcgcgct cccccagggc
     1081 cagggcgatg gccgtaccca agacgggggc caaggccatc acgaacagcc acagcggcac
     1141 cgcttcccgc aggagcaggt aggcgcccca cgcccctgcc aggaccgggg tgatgatcag
     1201 gcactggcgt gcggtcaggt tgaacaggac cggttcgggc cggtcgatgt cggcggggat
     1261 gcgtccccgc cacgcggaca cctcgtcgga ggccacagat actccttgtg ttcgttcacg
     1321 gccggatggt cattgctcgt tccggttcgt ccggggcggt gggaagagtc cgtactgctt
     1381 ccacacgcgc ttggggttgg gaaagagcgc ccgctggccc ttgacgtgcg gcggcttgcc
     1441 ccaggccagc ggcggcatgt cgggcaggtg gcgcagtccc gccgagggcc ggggcgccgg
     1501 gtccggcagg cccaggcgct gcacggcgcg gcggtcggga acgcgtaccg gtggcggggt
     1561 cggcaggatc ccctggcgcc atctgcgctc gggcggcgcg gacggcgccg accggcccgg
     1621 tggcggagcc ggacggggga agagggcctg ctggccggtc ctgggtgagc cgggcatgtg
     1681 gcccacctcc agctcgcggc gcaacgctgc gggcggtgcc gtacgcggtg gcgggaccgg
     1741 cggcagggcg cgcggtccgg gcagtgcgag cggaccgcgg gcgcggcctc ccgaccacgg
     1801 cgggccactt gtctctccgg agggcccgcc aacagggccg acagcgggcc ggggccctcc
     1861 tggccccggg ttggagtggc cgtggccggg tccgggcagc gctcgtcgac ctcctgggct
     1921 gagggctccg gccacttcag gcgggtcgtg gcgggcccgg taccaccacc cctggggttg
     1981 caggggttgc aggcccgagg ctggcttggg cgtgtagcgg ggcagtgtgc ggccgggcgt
     2041 gcgcggtgag aagaactgcc acttcaacga cgacgctgga acagagggca agcgcatgct
     2101 gctgaccgag cggaacgcca tcatccacgc gatgttcttc aggatcgcgg cgatgggcga
     2161 ggtacccggg ttgggctgcc agaccagctt catcacccag gagccgatcc ggatctgcac
     2221 gtacagcagg accaggagca gcatgatgtt catcagccac cccgcgtcac ccgcgtcgac
     2281 gtcgctgggc gaggcgagca cgctgctggc cagcacgaca ctcgtttcgg acccgagccc
     2341 ggtgtccagg accaggccgg gatccggttc cggcgcagcg gcggtctggt gcaacgatcc
     2401 gaagatcgtc atctgcccct cgaagaacag cctggccatg gcgatgaaca cgatcgactg
     2461 ggcgatcggg atcgcgcaca ggcccgccat ggacttccac cacagctccg cgatccggtt
     2521 ggtctgcggc agggcgtgga agatcagcag catcggcgcg gcgatggtca acacgatggc
     2581 catgcagatg cgcaccgcct cggtgaccat ccacaccacc agcagcacga ccacgaccac
     2641 caggagcagg atggtgaaga ccagcgcctc ctccaggatc acctccatgc ggtcgcgcag
     2701 gttctgagcg gcctcgcggg cgtcgatgcc ttgggctccg atggccgcgg agatctggtt
     2761 ggaggcccgg atcatctccc gggccgccca cagcgagaag ttcgaggcca cgaaggcgaa
     2821 caccgccctg ggcaggacgt cggcggccga gtagcggctc tgcaccgtct gatagcccat
     2881 agccacgatc ccgcccgcca cgatgagcag cacgaacagc gtgttgctgg tggccaggat
     2941 gccgccgtgc agggcctgca tcccctcggt cggctccggg gtgtggaagg ccttctcggc
     3001 cagccacccc agggccgggt tcaggccgga cacgacgaag tcggcgaacc agttcgacac
     3061 gtggcagccc ggatcgacca ggccgcagtc gaagacgtcc tcgtcggcgt ccacctccac
     3121 cggcacctcg gactgctccc gcagcggcgg ctcgtcctcg cgctcatcct gcgggggcgg
     3181 gagcgggtcg tcggtgatct ccggttccgg agccggtacc tcctccggct ccggttcggg
     3241 ttcgggttgg gtcccggggt cttcgggttc cgggagcggg tcgtcggagg ggggcggttc
     3301 cgggctggcc ggaccccgcc cccacggcgc ggggctcact cgccggcccc gcccacgctg
     3361 acgatccact ccacgatgtc catgagcacc gtggccagga tcgcgatgcc gtagccgacc
     3421 gccgttccgg tcagggcgcg cttggcgccg tcgatggctc cgacctcacc gttggcggcc
     3481 agccaccgca ccgccgcgat cgtcaggaac agggtcccca acgctgacgc gagggcgatg
     3541 atgaccatac ggatgcggtt cacgacctga cgcagctcgg ccgtctcctc ctcggccgac
     3601 tccgcggtgg cctcggcagc ccacacccac accgcgtcgt cgcccgctgc cacccaccac
     3661 acggccgctc cggcggcggc agggagcact gtcgcccacc ggacggcgtg ctgtcctgca
     3721 cctgaagctg ctgtcacctg ttccccctcg acgccctcgg ctcccggccg ggcaccggac
     3781 acccggtgct gtgcgccggg gcccagtgcc cgtatctggt cccctaagaa gcccggggaa
     3841 ggggtcggtg cgacatcggc ttcgagcgct ttttcgcgct tgtcaccagg agccggagcc
     3901 cgctccgctg ctccggaagg tccttcccgt ggacgagggc gtcggcgatc accacctcgc
     3961 ccgcgcgcac cgcctccagc aggcgtgcct cagcgcgttc gcggcgcttg gccacggcct
     4021 tgtaggatgc ccccagttcc gcggcctcct ctgccagcgg gacgttctcc agcctggtcc
     4081 gggcgatcag gcgcgcctcc gcccgcgaga ggacgcccac ccgcaccgcg gacaacagca
     4141 gcaggtccgg gctggcctga acccccgggt cggggtcctc ctgccgtccc gggtcaccgg
     4201 tcgggatcgg cgcctcctgc tcgtgcctgc gcgccgagag cgcggcgcgg tgcgcgggcc
     4261 gggtcaggta ccagaccagc cgggcgtagt cgaggttgat ggtgcggacc tggtggacca
     4321 cctcggacac gatcgcggac tccaccgtgt ccaccccgtc cgcggtcagg ccccggcacg
     4381 tcctcctggc ggtggagcgc agagcgggca ggcacagccc gagcgccccg accatccagt
     4441 cctgggacag gcgggcggcg cggatggtgt gccgccagac cgcgtcgcgc acgtcgtgcg
     4501 gggtgccctc gtccatcagg acgccgcgca gctcgtacag ggagtaggtg cggttctgga
     4561 gccaggggtg gacgtcggtc ccccgcaggg tcaggtgggt gggtgacagg cggacgaagc
     4621 cggtttcgac gactgccagc ggtgaagatg cgaaagccac ggatgccccc tcggatacga
     4681 gcgagaaatg acatccgcat gaaacacgtc ggcgttctca ggcagggttc acaacgggtt
     4741 cactgcttat tcaggggcca atcggtaggc actcaatccg tggtcgcgag ggtaaagaat
     4801 cagccaaggg ggcgcgggcc acacgcccgc gagcccctcg cagcaccagc agtgaacccc
     4861 atctgaaccc cctaccacct gcacatatac caacacggac aggagggtgg ggttgtctcc
     4921 gggcagcact catcagcggg gcagccgaag gggcagcgtt ttttcagaac acgcgcggcg
     4981 gcagaactca accgggaccg ctctcaaaac gggagagctc ttgccaacgc ttcttccttg
     5041 agagtcatgg gtgcaggaat gaagcacact gggacctttg gtcctggtgg ggtgccgtgg
     5101 cttatcagta gtctggccgc gcagacagaa ccgcccccgc ctcctggctt ggcgggggcg
     5161 gttcactcct tctggggcta gcgggagaac gcggcgccga ggaacgcgct ccactcgccg
     5221 ccggggaagg acaggcagcc caggtcccgg ttctgcgtgt ccctgacgag gacagcctcc
     5281 gcaaccgcag tctcgttgac ctcgacgcac tcgccctggg ctccgctgta gctggacttg
     5341 tgccacccgc tggtcaggtc gatcactcca agcctcccat ggctctcgaa atcacatcat
     5401 gtgaggctac agggggtagc gcccacgttt gcagctcccc gtacacggcc agcagccgcg
     5461 tcacggtgtc tccgccgagc agctcgccgc cggaggcgtg ctcgacttcg acaagcgtct
     5521 cgcgctcttt gaaggacagc agccggaacg ggccagaggc tcccccgtag tacggggtgt
     5581 ccgctggcag gatcaagatt ctcacgaccc ctgcggagtc cagatcgagg agatgaccca
     5641 gctgctcctt catcaccgcg gacgagccga cacgggctcg aacgaccgtc tcggcgagga
     5701 tcgcgaccag acgcgggttg ttcatccccc tcagcgcgtc gagacggctg accctcaggt
     5761 ccacgagccg gtcgatttcc tcggacgtgt ccaggggccg accgtcgcgg aagatctgac
     5821 gcgcgtagtc gggcgtttgg aacatacccg ggacaagggc gggattccat atctggatcc
     5881 cggacgcctg ctcttcagcc gtgacgatct ttcggtgcca gtcggggtcc tcctcggccc
     5941 gcttcgcctc tgtccaacga cggagaaggt caccgttcgt actgaacagg gcctccgcct
     6001 cgttgagaaa atcccttttt ggtgccctat aggcgttctc atatttactg atggttgacg
     6061 caccgtatcc ggtcgcctcg gccacctgat ccagcgtaag tccacgccga tcgcgcagcc
     6121 tgcggagctc cctcccgaag gtgatccatg atgacagcgt cttctcaggc atgggtagaa
     6181 ctttacagaa gctctctaca ttcctgtacg ggttccacca aatagcagcc gatgcacgta
     6241 aaggcattga ggcggagcac ctcgccctgg acgatgggca ccacggcgga aagcgccggc
     6301 cacaggaaac cccggcgact gcgccaccag ccccgggaac ggctcccacc gaacactcca
     6361 gaggtgagaa cgtggcaaat cctaccgaat cagagattcc aaccagcact tcgcgcactc
     6421 gtccgcaaga aggcggagtc cggtttcccg gagagcgtac gaacgtcttc cagcgggctg
     6481 atgaagtgcg gcccgctccg gaagtcgtcc tgtcggctgg tgaggctgtt gtggctgctg
     6541 cccactcccg gaaggcgcag gcggccgcgc gcaggtcctt ccccggaatc ccggactcgg
     6601 tggcacacgt ccgcgactgg gtcgagcaga cctgcgcaca gtggcaggcc cccgtcccgg
     6661 aggtgctcac tctggtggct tccgagttga cctccaacgc catcgcccac acccacagcg
     6721 gcctgccggg cgggcagttc gctacccgcc tcctgctcta tcccgaccgc atgcggttgg
     6781 aggtacgcga cgccggcccc ctctccggcc ggaccccgct gcgccgtacc cccgccctca
     6841 ctgccgagca cggccgggga ctggtgctgg tggacgccct cgccaccggt tggggacggc
     6901 tgcccgcagg aaccgggacc ttcgccgaac tcacgcgagt gccaggggag gagtgaatga
     6961 ggctcccgcg acgcacccgc tcccgccctc tggtcgtccg tgctccggct ggcttcgacg
     7021 acgcccggtg gcgcgccgcc cagcagggct atgtcctgac ccgccagaag cgcttgctgg
     7081 gagcggtgta cgcgctcacc tctcttgacg gagacaccgc gatcctccac ggcctcgggg
     7141 aggtccgcgc cttcctcgac cggccctcat gacggcgtgc ggtgacggcc ccgtggcccg
     7201 tcctgcgacc gcggccacaa cgtccatgcc cctccccgaa caggaacgag aggacctgtg
     7261 ctcgcatccg cgccccacga cctgaccatg acccgaaccc gcgcggaccc gctggccgag
     7321 accgcccatc tgacccacgt cacccgcgac gcagcacacc acctcaccgg cgcggagctg
     7381 gtgcgcctgg ccttgaacgg ggaacgcggg cgaacccctg acggtgcgcg ccctcatcga
     7441 cctcaccgga caccaacgga aagcccctca tgcccgacta ccgctacctc ctcgacggcc
     7501 gccccgacgt cctcaccccc ggtgaagtcg cccaactgtt caacattcga ccccgcagcc
     7561 tccaccgagg cgaatgggac aacgtcctcc ggcccttccg cacccccggc ggagcacgcc
     7621 gctaccccaa agaacacatc gccgccctcc tcaaccagcc ggacgattcc gcccccgccc
     7681 cctgaagtcg tcacgagccg gatccgcgca tcttcgtggg aagcccggac caggtacggc
     7741 acatggaaat cgacgaaccg ctgccggagg caaccgtcta cgaggcggcc gtggtgtacc
     7801 tgcacgccta cacccgcctc gaacgccgcg acggagcggt caggatcgcc gccccgacct
     7861 cgccacccac ctgtgcgaac agctgaggca gctgtgccgg gacgccgcag ccttcaaagc
     7921 cttccacggg aaggtggcat aaccaactgt ccccggcttc caccggatca ccgcttcacc
     7981 aaaacagcgt gcaaccgccc tcacagcccg gttttattcc caggcaggaa tatccggcca
     8041 gagattgacc ggacccgctg gcctctctac tgtaaattcc gtttcgaccc tttcggaaag
     8101 ggccatgcca tgaagttcga gaagctctcc ggcgactgca accgggatga ctgcccggga
     8161 atctactcca ccgacaacgg gaccgtcgtc gtgcagggcg cgctcctgac cgacaccacc
     8221 ggcctcaccc cctcccccgg agaggccgcg gtcgagatcc ccacgcacct gatcgaggag
     8281 gccgcccgtg cgcttggaag gtgacgcctg gcgggagttc ttcgactcct tccagcacga
     8341 ggcgttccgc ctggagactc tgcccagcta cacggtgccc gaggaggaag aggagctgcg
     8401 ccggttcctg gctggggaga cccgcccggc cgaggagctg cacaccgaca gctacctgct
     8461 ccgcgtgcgc aaccacgtcg agtccggtcg ccggatccga cgggtccaca ccctgaccag
     8521 ccctgtcggc gaccacctgc ggttccagtt cgagtggggg tacgccttca gcgtgcaggc
     8581 cggtgaggag gtcaacatcc tcgacttcgc caccaccccc gaccccggcc tgccccgcca
     8641 ggacttctgg ctcttcgacg acacccgtgt ggtgctcatg cactacgctg ccgacggaac
     8701 ccagaccggc cgggaactcc tggagggggc cgactccgcc ccctacgtcg cctacaagaa
     8761 cctggccctg gagcacgccg tccccttcac cgagtactac aaggccgact gattgacgct
     8821 tgagcccgac cgtgcccaac agccgcgcag cgagctggcg gaggcccttc gcagccttcg
     8881 ccgcgcctcg gggctgaccg gcgcgcggct cgccgtccgc agcgggatga gccaggccaa
     8941 ggtcagcaag atcgagaacg gccgcgtgct gccctccgcg ctggacgtcg agcgcatcct
     9001 gcgtgcgctc gacgtcccgc ccggggagga tgaggccgcg cgcttgctgg agctggcccg
     9061 tgtggccaac accgactacc aggggtttcg taccgcgctc cagcgcgggc tcggggagac
     9121 gcagcgggac ctggccgcga tcgaggcttc ggcgtccacc atccgcttct tcctgccctg
     9181 catgatcacg ggactcctcc aaacgccgga ctacgcgcgt cagaccctgt cgcacacgct
     9241 ggtgaaccgc ggggcgagct gggagacggc gctcgctcgg cgcctggagc gccagacggt
     9301 gctctacgac gagggcaagc gcttcgtgtt cgtcctgacc gaggccgcgc tgcgctggcc
     9361 gctgtgccgc ccggaggcga tggcggtgca gatggaccgg atcgcctcgc tcagcgagct
     9421 gcccagcgtg gacatccgcg tcgtgcccgc cgatcccccc gtgcccagcg gccctctcaa
     9481 cgggttcacg gtctacgacg accgcttggt gaccgtcgag gtgttcacgg gcaagctcgc
     9541 cctgcgcgac ccgaaggatg tcgcctacag catggagata ttcgcattct tccatgacca
     9601 cgcactcgag ggcgaaaaca ccaggccctt cctgcgcggc ctcgcccagg aataccgtaa
     9661 tcgggcataa ccggcgcggg cccggacgaa tttattccct ggcgggaaac gccttcacct
     9721 gtcttgtgcg ggtccctaat ctgagctgtg ctcacaggcc cccatgagaa aggaaagacc
     9781 tgtgcagaac acgcaggaca gccccagctc ggaatctccc ttcgccctcg acatccggct
     9841 gatcgagaac agcgactccc tggcccagct gatcaacctc accgatgacg gctgcggctc
     9901 cagctgcccc aactcctgca ccacgagcgc cgcggactga tcggcacggt cggcaccggc
     9961 ccggatccgg tgccgaccag cacttctggg aggaggggat atgggttccg gcgaggagcg
    10021 gcacgtgggt tggcgtgtgg tcggccgacc gctggtgcgg gcgagcctgc tcagcggcct
    10081 accgacgagc ggcgtaccgg acctgagcgg cagtgaccca catccgtggt tgaagtggct
    10141 gcgccgcgtg tgggagcacc cgggtctgac cgaggcgatc cggaacgcct cgcctgacct
    10201 ggccgccggt gtggaggctc tgctcgacca ggatccggcc gcggtgcggg tacgccgggc
    10261 ccggaaggcg accgcttccg ttctgcgcta cgtactgcgg gccgacagcc gtgccactcc
    10321 cttcgggttg ttcgccggtg taaccgccgc gaccttctcc gaacgctcac gagtggtgtg
    10381 gggtggcgcc caccggaggg tggtttctcc gggcggggca tgggtggccg aggtcgtcgg
    10441 cgcgttggag gctccgcctg tggtgcgtga gcacctgctg gtcgtcgtca acaacaccgt
    10501 cgttgaagag cgcgggcacc tcgtcgtgcc ccagtacgcg cgtcccgccc cgggtgcgcc
    10561 cgggtcggac gcggagcagg tcgaggtccg tgtcaacagc gccgtacgcc tggtcctgga
    10621 aacagcacgt gaacccgtgt cgtggtcgac gctccgggcc aagctggccg ccgaataccc
    10681 cgatgaacct gccgtgagca ctgacgccat gctcgcccgc ctggtccagg tgcgggcgct
    10741 gctcacctcg ctcgcccctg cgtccaccga aaccgactcc ctcggctgcc tcgtctcttc
    10801 ccttgcccag cacaacacct gcgctccacc cgaaacccgc ccactgatgt cgcttctcca
    10861 gaaagcgcac acggcgatgg aggagcacaa ctgcggtggt aggtccagca ccctggggaa
    10921 ggccgacgag gcggtctcgc gcgtgtcccg ggttcagccg ttgggggtgg acgtgcgagt
    10981 ggacgccgac atggccttgc ccgtggcggt ggcacgcgcg gcggagcagg ccgcgcacat
    11041 gctgaccgtc ctgtcccctt atccggacgg gctgcccgcg tggcacacgt accgggagcg
    11101 cttcgccgac cggtacggcg acgcgctcgt gcccgtccgc gaggtcgtgc atcctcagac
    11161 ggggctgggc ttccccgccg gatacgccac cgccgacgcc gaaggccgcg ccgagtccct
    11221 caccagtcgt gaccgttggc tgctcgagca ggcccaggct gccgctctgg accggcggcg
    11281 ggagatcagc gcagacgcgc tcctggacga actggccgcc cggcagtccg cgctacctcc
    11341 tgggcacacg gaactgaacc tgcgtgtgga gtcaccctca cgagccgcac tggacagcgg
    11401 ccggttccgc gtcgcggtgc tgggcgcctc ccgcagcgcg gccaccatgg cgggacgctt
    11461 cgccgccctg gccggtgtcc gaggcgacct gcgcgaagcc gtctcgcgca ccacctccgc
    11521 cggggcggtg ccggtgcagc tgtcgttccc gccgctgcga gcccgcagct cccacctggt
    11581 ccgctcggag aggcttctcg atcacttgat cagcgtgggc gaataccccg cttcagtgcc
    11641 cggacagctg ggtgtggacg atctcgcggt cgggtgcgat gacggcggcc tcttcctgtt
    11701 ctcacgcatc ctggcgcgca gggtcgagcc tgtcgtgccg cacgcgctga acctgcgcta
    11761 cgccccgccg atggcccgct tcctggccga actcccccgt gccggacgcg cggtggttat
    11821 cgggttcgac tggggcgcgg cctcctcgct gccgttcctg ccccgtgtgc gctcgggcaa
    11881 catggtcctg gtcaacgccc ggtggcgggt cagagccaac gaccttcccc cgcgtaccgc
    11941 gtcgtggccg cggtggcgac aggcgtggtc tacctgggct gagcgccgca acctgcccgg
    12001 cgtggtggac ctgggcaagg gcgaccagcg gctgcgcctg gacctttcag aaccggcgca
    12061 cctgttcctg ctgcgcgccc agctggacaa ggaaggcggc acggttctca ccgaagcgcc
    12121 cgacccgcgc tcgtccggat ggtgcgaggg gcggccgacc gaggttctcg ttcagctctg
    12181 ccggaaggag gccgcgtgaa caccacgacc accgaagcga cggagatagc aggactggtg
    12241 gccgaccgcc tggccacacc cgagcagggc cgtgctctgg ccggagagcg gtggtggccc
    12301 cagtcgctgg cacatggcgc ggccggggtg gcgctgttgc acatcgaacg cgcccgcacc
    12361 ggtcacgggc cgtgggaccg cgtccagcgg tggctggagt gtgcggtcgc cgagggcgcg
    12421 gactcctccc ccagcgcgca cctgtactac ggcgcgcctg cggtggcgtt cgtcctacac
    12481 cgggccgcaa cggtccaccc ggggtatgag catgagcttg cccggttgga cagggccgtg
    12541 gaacggatcg tgctctcccg attggagcgg gcgcacgcgc gaatggacgc cggtgggctt
    12601 ccgctacttt cggagttcga caccatccgg ggcctgaccg gactgggttc cctactcctg
    12661 gcccgcgacc cgcagggccc gctcctccgg gacctgttgg cctacctagt gcggttgacc
    12721 gagccggtca ctgtccacgg ccgtacgctc cccggttggt ggagccctgt cggccccggt
    12781 ggaaagaaga acgccgcctt ccctggcggg cacgcgaaca ccggtatggc ccacggcatc
    12841 gccggtcccc tgaccctgct cgcagccgcc ctgcggcgcg gaatcacggt ggaggggcac
    12901 acagaagcca tcgagcgcat cctggtctgg ctcgacacct gggaacagac gtctccggcc
    12961 ggggcgtggt ggccgtactg ggtcacccgc gcacagctcg acgggacctg cggcctggtc
    13021 ggcccgcagc ggccctcgtg gtgctacggg gccgccggtg tggcccgcgc gcagctgctc
    13081 gccaccgacg ctctgggaga tcagcagcgc tacgccaccg cgcagagcac ccttgcccgt
    13141 ctcttcaccg aggagccgcc catggcgttg gactcttcgc tgtgccacgg ccgtgccggt
    13201 ctggcggtgc tcgcccacgc caccgcgctg ggcaacgccc ccgggctgtg cgccgcgctc
    13261 tcggacggcg atgccgccgc ggtggcgaac ggtcttctcg ccggatccgg aatcggactg
    13321 ttggaaggcg cggcgggtat cgccatcgcc ctgcacacac tgcacaaccc cacccccgac
    13381 ctggggtggg ccgccttcct cctcctcgac caccaggagc accacgctga tgggtgacga
    13441 gcagccgcag atcctcatcc agtgggtcga ctgggccgcc gccgagcact ggggcgttca
    13501 cggcctgggc ccggctctcg aaggagcgcg caaggaggga ctcatcccgg cgtggtggtt
    13561 cgtccgtaag aagccccact ggcggctgcg ctacaccgga ggccgcccgg cccggcagtt
    13621 cctggacacc gaactggagc gcctccacgc tgagggcgcc gtcaccaggt gggtgcacgg
    13681 catctacgaa cccgaaaccg gggcttttgg cggaccggcg gggatggcgc tggcccacgc
    13741 cgtgttcggc gaggacagcc gacacctcct cgcctacctg gggcaccgca gcacgatgtc
    13801 cggcacggaa ctcggccgcc gtgaactcgc cctcctcctg gggagctcct tcctgcgcgg
    13861 tgcccggttg gactggttcg agcaggccga cgtctgggcc aaggtcgctg ccctgcgcgc
    13921 tctcccccag cccttcagtg cggaagagga gctggtttcc tcggcgcgca ccctcatgac
    13981 tctcagcccg cgccccctta tcgattcggg gccgctgcgc cacaccagcg cctgggcgca
    14041 ggtgttcacc gcggccggag ccgccctgac cgacctcgcc gcccagggca ggttgaaccg
    14101 gggcctgcgc gcggtgtgcg cccatcacct gatcttcgcc ttcaaccggt ggggcctgcc
    14161 ctaccgggac cagcacatcc tgtccaccac cgccagaaag gccgccatga ccgacaccaa
    14221 ccaccgcgcc acacccgagt ccgcccaggc cctgcgcgaa gaactcatcc ggcagctacg
    14281 gaaggacggt gtcctcacca ccccggcagt ggagggagcg ttccgcgcgg taccgcgcca
    14341 tgccttcgtt cccaacgcca ccctggagga ggcctacacc aacgcccccg tacacatcaa
    14401 gcacgacgac aacggcgcct ccatcagttg cggctcccag cccggagtcg tcgcgaccat
    14461 gctggaacag gccgccctgg aacccggcat gcgcgtactg gaactgggcg cgggcaccgg
    14521 gtataacgcg gccctcctcg gtcacctggt cgggccgacc ggttcggtca ccaccatcga
    14581 cgtcgaccag gacttggtcg aaggcgcgtg tgcccggctg aaagagaacg gcgccaccaa
    14641 cgtcactgtg gtcctgggcg acggcgcgct cggtcacccg gacggcgcgc cgttcgaccg
    14701 gatcatcgcc acggtgggtt gccacgatgt gccccgcgcc tgggtggacc agctcgcccc
    14761 cggcggcagg ctcatcgccc cggtgcgcat cgccggagac gtctcccgct ccattgtctt
    14821 cgaagcccgt ggcgaccact gggcgtccgt ggacagccag ttgtgcacgt tcatgcccct
    14881 gcgcggcggc gtcggtgacg acccgcgccg catcctggcc ctggacggcg acgggacggt
    14941 catgctccag gccaaccagg accagagcat tgcacccgag caggtggacc acgtgctcat
    15001 cgagccctcc gccaccacct ggacgggggt gaacttcggc aaaggacagc ccttggatcc
    15061 gatgtggctg tggctgtcca cccggctgga caaccgcgtc tcacgcatgc cggttcagcc
    15121 ccaagccgtg gccagcgacc tggtctcccc cgggctgccc tggggtgaca tggccagtgt
    15181 ccccgcaggc gagcgggggc tggcgtatct gacgatgcgc ccggtggcag gtcagcaggg
    15241 ccgccatgag gtcggcgtca tcgggcacgc ccataccggg cagaagctgg ccgagcagat
    15301 ggccgagcac atccgggcat gggaacccca ccgcgccgag gaactctcct tcgccctgca
    15361 ctacaacgcc gtcccggaac cctccaccgt cactcggcgg gtgctggcgc gggcccactc
    15421 caccctggtg gtctcctggg gcgagcccgt atgaggttcg cgcactggtt ccctctcatc
    15481 cctcggccgc gcccacccgc ggacagcctg gccgcgcgcg ttgaacgcct cgccgcagcg
    15541 gggcggaccg cacgttccgg atcagatgag gaggcgctgg ctgccgctgc gcaggtctac
    15601 aacggcgcgg cgttgctcgc ctccgacgtc ggactgcccg agctggcacg cgactggtgc
    15661 tgggagcacg cacacgcgta cctgacacac ctaccgctga acgccaccat ggcccaacgc
    15721 gccctggaac cggtggtcaa cctcgcccgg cttcgcattc gcgcaggcca cggcgcggag
    15781 gccttcacga tgctcacagc tctacaggaa ggggtgcgcg cggccacagc caccgtgatc
    15841 gacagataca agcttccctt ggaccaactc accgtctccg atgaggaccg gggggagttg
    15901 caccgctggc tgtggacggt ctacatggga gacggcatgc gggccctggc gtcggaggaa
    15961 aggtggcagg aggccgcgaa gcaggcccgg cagcacggcg ggatcggcag ccgtcttttc
    16021 gacggtcgcc aggtcaccgt gatcgcagag atgatgtccg ataacccagc cagcgccctg
    16081 gccatgatcg agggtagcgt tgcccgagaa ccatgggaga aggccgtcca agcagtcctg
    16141 gctctgtggt gcctcaaaga atctggtgag accacggtcg acgatgcgga gatggccctg
    16201 gaccgtgtcc gtgacgtcga gagccgccag gtcgtgttca ccacacggct cgggatcgtc
    16261 gcaacgaagc tcaccggagg attccgggga ggcactcctg cactcttgtc acagctggtc
    16321 tctgatgtag tccaagcaca ggacggatac gcggcacggg acctgctcaa cgcttggaag
    16381 caggagttac cccaagatca ggtggatgca ctggggtccg tgctcaaggc gtcggggatc
    16441 gacacaaagg cgttaccgca agcgtctctt catgcgctca gagcaacgtt ggaagaagcg
    16501 aatcgaagtc tccgagatgg ttgtatcccg gcatgaccag aggtcccgca gccgtagagc
    16561 tacaggccca caccaggatg ctcctgggag aaggccaatt gcctgttcgg tgtcacccgt
    16621 gccactgccc accgctggtt ccagacctgg accgagatgg gcctgtggcc cacgatccac
    16681 cgcacagtcc tggatgagct gggcagacgc gccctgctgg actggtcccg cgccaccgtc
    16741 gactcccagt cgatccgcgc caaaagaggg ggagaacacg gggccaaacc ccactgatcg
    16801 cggcaaaccc ggctccaagc tccacctgcc gtgcgaccac cagggcctcc cgctgacctg
    16861 cgcggtctcc gcggccaacg tcaacgacat cgaagcactc caacccctgg tccggggtat
    16921 cccggcggtg cgctcacggc gaggtccccg gcggcggcgt ccggccaagc tccacggcga
    16981 caaggcctac cactgcaggc tccgctatga ccggcgaacc atcgactaca tgcgtcgacg
    17041 tagtaccgag ggtctgtcga agaaggacgt gttgcactgc ctcaagcact tcatcgctcg
    17101 ggaggtcttc cacgacatca agaccgaccg tggcctcgct tgacatctat aggaccgtcc
    17161 cagcacgcaa taaaggtcag gacctcatac cacttgacac ctcctggctg tcggaccacg
    17221 ccgataggat gaggcgagcc gcccagccct ttcctagacc aggagatcta tccctcgtgt
    17281 cagtcctgtc cagcctcgta tggagcgtcg ccgacaccct gcgaggtcca tacgccgagg
    17341 ccgagtacgg cccgatcatc ctccccttta cagtgctgcg ccgcctcgaa tgcgtcatgg
    17401 ccccgcaccg cgaggtgatg gccgaaatcg tggcacagta ctcaggagag cagcagcggc
    17461 gcacgcacct gaaactcaat acccgcaccc aggacagcgc ggggctgtcc ttctggacga
    17521 cgagtaacta cacactcaag agggcattgc aggacccaaa caacctggct gagaacctca
    17581 tcgactacgt cggtgggttc tcggcgaacc tggacgtctt caagtcgttc gacttcgaga
    17641 ccgtgatccg tacgcttgat acccgcgatc gtctcgccca ggtcgcccgc cactttgaga
    17701 agatcgacct atcgccagac gcggtgtcca acgccgacat gggtgacctg ttcgaaaacc
    17761 tgatctaccg gttcgccgag tccgccaaca agggtgctgg ccagttctac acgccacgtg
    17821 acgtcgttcg acttctgatc gatcttgtct acgcggagga tactgaggcg ctgcgtgatc
    17881 gcggcacggt gcggtcgatc tacgacccca cggtcggaac cggcgggatg ctcaccgtcg
    17941 ccgacgagca cctgcacgag ctcaaccccg acgcctcaac aggtctgttc ggccaagaga
    18001 tcaatccgca cacctacgcg atctgtaagg cagacctgct catcaagggc caggacccgt
    18061 ccaacgttcg tcagggtgac acacttgtcg tcgaccggtt cgagaaccag ggcttcgact
    18121 atgtgctgtc caatccgccg ttcgggaccg actggaaggc tgtcgagtcc gccgtgaaga
    18181 acgagcacgc ccgtggcggc cagggccgct tcgccccggg actgccagcc gtcggtgacg
    18241 cagccatgct attcctactg catgtggcgt cgaagatgcg cgacgtcgac agtacgggcc
    18301 gtggcggtaa ggctggcatc gtcctcaacg gttctccgct gttcaacggt gttgcgggct
    18361 ccggcccatc cgatatccga ggccacatgt tggagaacga cctggtcgag gccattgtgg
    18421 cactgcccaa cgacatgttc tacaacaccg gtatcgcgac gtatctgtgg atcctatcca
    18481 acgcgaagcc ttcagagcgt aagggcacag tgcagctgat cgatgccaag gggcttgggt
    18541 cgaagatgcg gaagtcgatc ggcttgaagc gaatcgagat ctccgaggcg caccgtaagg
    18601 acatcgtgcg cgccttcgtc ggtaacgagg ttgagcccga caaggccacg gtaccggtca
    18661 aggtgttcgc gaaccgtgac ttcgcatact ggaccgtcac ggtcgagcgc ccgatgcagt
    18721 tccgttttga gtgcacaccg gagaccatcg gagcggttgc cgagcacaag aagctcggcc
    18781 agatcgctgg cctcaccgag gcactggagt cattcggcga acagccatac ctgaaccggg
    18841 agaagttcct caaggaactt gatggtcacc tccgagatca cggtatcggt ctgacgacgg
    18901 cgcagcgcaa gtcactgtgg cagaccatcg gcgtccacga taaaaccgcc gacatctgcc
    18961 tgcacacctc gggcatgcgg aagggcgagg tggaaccgga tccggcactg cgcgacaccg
    19021 agaacatccc cttcggatgg ggcgggcacc caaagaccca cgaggccctc aagcagaccg
    19081 ttcaggccta tttcgacacc gaggtgaagc cgcacgtcga caacgcttgg atcgactgga
    19141 gcaagaccaa gaccggctac gagatcccgt tcgcccgcca tttctacacc tacgagccac
    19201 cccggccgct cgaagaaatc gacacggacc tcgagcgtgt cgttggcgag atcatgacct
    19261 tgttgcggga ggtggagtcg tgagtgtcga agctgcgaac ccggtcgaag agcgggtcga
    19321 caagtggctc gggggtgtcc catcagggtg gacaggtgct cggctactcg aggtcgcaga
    19381 tgcctggccg agcaacgtag ataaacacac tgtcgaggga gagccacccg tcaggctctg
    19441 caactacatg gacgtctaca agaacgactc catcgtcgac tcactcgact tcatgacagc
    19501 cagcgctacg cgcgaacaga tcaagaagtt ccgaatccgt gtcggcgaca cgctcatcac
    19561 caaggattcc gaaaccgcag acgatatcgg catcgcagcc ttcgtcgagt atgaagctga
    19621 cgacctagtc tgcgggtacc acctggccat tgtccgaccc gatctgcgaa gggtccttcc
    19681 taagtacctg tactgggtac tcaactctga gcccatcgca cgccaatggg gtgtcacggc
    19741 ggcgggtgtg acccgcgtcg gtattcgaag cactgagctg aataaggtca cgatgccact
    19801 cccgccgctc gacgagcagc aggccatcgc cgaatacttg gaccacgaaa cggcccagac
    19861 tgatgcgctc gtagcgaagc aggaggagtt catcgggctc ctgcgtgaac gacgttctcg
    19921 taaacgtgaa gtgctcgcca ctcgggtcgc caatggacag cggttgcgat gggtgctcag
    19981 cgaggtcgac aagcgtgctg gtgcacgggg cggggatctg ccgctcatgt cggtgtcgat
    20041 caactggggc gtccggcgtc gggacgagac cacggacagg cttgcccgcg ccgaagatct
    20101 cagtcactac aagatatgtc tcgcaggaga cgtgattgtg aaccgtatgc gtgccttcca
    20161 aggcgcgctc ggcgtcgcac cagaagatgg tgtcgtaagt ccggactatg ccgtactcag
    20221 ggccaccccc gaagccgacc cgtattggct ggctgaactg atgcgtacga aagcgttcgt
    20281 cggtgagatc atcctgaggc tgcgaggaat tggaggcact gacagtggca atgtgcgtac
    20341 gccacgaatc aacaccgtcg acctccttga tatccgcgca gacgttccgg aggtgacgac
    20401 ccaacgcgcg gagctacaga atctccttat cggaaaccac cgtatcgact ccctgatcgc
    20461 caaggctgag gaacacatcg ctttggccaa ggagcgtcga tcggcgctgg tcacggccgc
    20521 ggtgacaggg cagatcgacg tacgcgcggc gaggaaggcg agctaaggac gatggcagca
    20581 cctgacggga cgcacgagaa ggctttcgag atcgaaatcg ccgagtacct caccgcgcac
    20641 ggctgggagt acagcgagac cgacgacggc tacgacgtcg agcgggcgat ctggcccgag
    20701 gacgttcact ggtggctgtc agagacacag cccgacgagt acgccaaggt cgtgcgggtc
    20761 ggcaccgctg ccgaagccgc tgaccgcgag gctctgctgg cctccctcgt gacccgcctg
    20821 gacacgccga tgagttccgg tggcggcacg ctgaacgtgc tgcgaaggaa gttctcccac
    20881 acccgggggg cgacggcgca cctgcggatg tgccaattca agccagctac gacgctgaac
    20941 cgggacgtca gcaggcagta ccggaaggtc cggatgcgtg tggtccggca ggtgcacttc
    21001 tcgccaaagc ggaacgactc acggtcgatc gacctggtgt tcttcgtcaa cggcctacct
    21061 gtggccacgt gcgagttgaa gtcgttcttc aagcaggagt ggcgcacggc agtcagccag
    21121 taccgcaacg atcgcaaccc ggcaggccag ccgctgctcg ggttcggcac ccgtgccttg
    21181 gtgcacttcg ccgtcgacga cgaccaagtc cacatcacca cgaagctggc cggcgaaaag
    21241 acatacttcc tgcctttcaa ccgtggcaat gaggacaccg gtgcggccgg gaacccgccc
    21301 aacccgaacg gtgctgcgac gtcgtacctg tgggagcagg tcctgcaacg cgacaactgg
    21361 ctggcgatcc tcgggtccca gatgttcctc aagatcgaga ccgacgagga tcctgtaaca
    21421 ggcaagatca agcggtccac gacactgatg tttccgcgct accaccaatg gcgcgcggtg
    21481 aacaagctcg tcgacacgat caccgaggag ggccccggtc gccgatacct gatcgagcac
    21541 tcagccgggt cggggaagac gaatacgatc gcctggacag cgcaccggct ggcccggctc
    21601 cataatcagt cgaacgagaa agtgttcgac aaggtcctga tcgtctcgga ccgccgtatc
    21661 ctggacgcac agctgcagca ggcggtcgag caggtcgatg acacggtcgg caccgtcgcg
    21721 gtcatcgact ccgccgcagt gcgacgatcc ggcggctcca agtcgcgggc gctgttggac
    21781 gcgctgaccg gctcggcact gatcgtagtc gtcaccatcc agacatttcc ctacgttaag
    21841 ggtctcctgg agacgacgtt gggcgatcag agcttcgcgg tgatcgtcga cgaggcgcac
    21901 acctcgcaat cgggtaagac ggctgctgac ctgaagaagg tcctcaccga gggcgggcag
    21961 gtcactgacg aggacgagct cgacagtcaa gacatcatca accaggtggt cgaggctgat
    22021 gtcgcccgcg aacagcaaat cgctgccgag actgcggcgc gtgccagggc tcggaacata
    22081 tcgctacttg ctttcacagc gacccccaag gcgaagacga agacactttt cgggcgcgat
    22141 aacgacgagg ggaagccggt ctcgttcgac gtctacccga tgcggcaggc gatcgaggag
    22201 gggttcattc tcgacgtgtt gcgcggctac cagacctaca ggaccgcctt tgagatcgag
    22261 cagcgcggcg agcacggcgt cgtcgccagt attgccgagg gtgaaggagc cgatgacgga
    22321 tcggatcggc tcgtcgatcc gaagatcgcg tcgcggaaga tcatgcgatt cgcgaacctg
    22381 cacccaacca acgtagggca gaaggtcgag atcatcgtcg agcacttccg cgctaacgtt
    22441 gcccaccttc tcgacgggca cgcgaaggcc atggtcgtga ccgactcgcg ccaggctgcc
    22501 gtccgctaca agatcgagac cgacaagtac ctagcgcaga agcgctacgg ctatcagacc
    22561 atcgtggcgt tctccgggaa gatcggcgac gacgtctacg gactgaccga tgctaccgag
    22621 gcgtcgatga accccaacct cggctcggac ctggcgcggg agttccgtcg gccggagtac
    22681 cagctaatgc tggtcgccga taagttccag accgggttcg atcagccgct gctgtgcgcc
    22741 atgtacgtgg acaagcggct tcccgacgta cacgcggtgc aaactctgtc gcggctcaac
    22801 cgcatctacc gggctccctc gggtgaggtg aaggaccgga cgttcgtgct cgacttcgtt
    22861 aacgatccgg aagagatccg cgaggcgttc ctcacctatt acctcgaggc gcatgtcgag
    22921 acagcgacgg acccaaacct cgtccaccgg ctcgcgacca agttggccca ggcacggatc
    22981 tacacgtcgg tggaggttga acgctacgct gaggcctggt gggcaccgac ccagtcccat
    23041 gcagctctcg ctgccgcggt cacgccagcg cgcgacgagt tcgtgaaccg atgggcggat
    23101 gcgaccgggc ggcacgacgg ccaagcgctc gatgagctgc ggactttccg caaggactgt
    23161 ggctcctacg tgcgcctgta cgacttcatg tctcaggtcg tcgattacgg caccagcgac
    23221 ttggagaagc tggccgagtt cctgcgtcag ttggtccgac tgctcgcggt cgacgagccg
    23281 agcgcggacg tcgacgtgtc cgggctcgag ttgcgcaggg tccggcagat taatcagggc
    23341 aaggccgaca tcgggctgtc cggggaccag gacacaccga gcttagctgg catctccggg
    23401 gtcggaacgg ggctgtcgcg gcaggatccg cagcaggagt tgctctcgaa tgtggtggct
    23461 cggatcaacg cgctgttcgg ctcggagttt gccgatccgc agatcgaggg gttcgtggtc
    23521 gcggcggccg gcatggctga ggaggactca cgcatcgctg atcagattga tcacaatgcg
    23581 ctcgatcagt tcatggcctc accccagctg cgagagaccc tgaccgacgc ggcagtgctg
    23641 aacgaggggg cgttcggcaa gctgaccggt gcgctcactg gggagagtga tcgcgctgac
    23701 gagttcatcc gcctcatcgg tgcgtacctg taccagtcac gtcggcttcg gactgtcaat
    23761 gcagcagatc ccgaagacgc cgatgcctca gatgagcccc agtgaggcat tgccagtgga
    23821 aacgagaact ccacatcctg ttgcgtgccg ggtgtgatgg aggctctggt gtgggccgga
    23881 accattcccc gcccctcccc aacgctctac cttgatctca ccctcctagt tcgacgaagc
    23941 tctcgacacg aaagctcccc cgatgaaccg ttcccctgaa gagccctgga ccatcaacga
    24001 cctccggtcc gcctacgaac gctatgccga gattgtcaac accagcgacc tggccccgtc
    24061 gacgaaaacc acctacctcg tccacgccga ccgattcgta cgctggatgg ccggcgagat
    24121 cagcatccga ggcgaacagt gaccttcgag cactccgacc gctccactcc ctcggggaga
    24181 acctccggga cccacatcgt catcaccacc gacaccgatg actgctacca caccggtgag
    24241 gagtgcacgg cgttccgcgc gaaccacacc gccaacgagg cacaagcaaa aggtcgacgc
    24301 cgcaccgtgc ggatcaccgt ggccgacgcg gaagagttcg gccgacggct gtgcaccgtg
    24361 tgcggcgcgc aggagcgcgc gaacgccgaa cagccgaagt tcctacgcga gctccttgcc
    24421 gacctcagcc cggccgagaa acgaaggcgg caggcctgga tccggcgtga gcgtacacgt
    24481 gccaacgggc ccgtcgagag gttcaccacc cgggagatcg gtgaccggga caggtggctc
    24541 tgcgggctct gccacgaccc tgtcgatccg tcctgcaagg ctcgtgaccc gcgctccccg
    24601 agcgtcgacc acatccgagc cgtctccctc ggagggaccc agacccgcga caacgtccgg
    24661 atcacccacc tgggatgcaa tcacgaacgc aacaacagca ccgagttact cgacctggaa
    24721 gacgcccgaa gagtacagga gatcatcgac taggtcctcg gtgtgaaacg acaggtcacc
    24781 accgcggaac tggaagcagc gctcgaacac tctcgggaac aacaccatcc ggatcagtac
    24841 cggcagagcc tccggcgagc ggtccagaag tacgaacgcg gcggccggga ctcttcacag
    24901 ccgacgtgag tccggcgagc cggacctcgc ccgctggccg acctcacgag tcaccaccgc
    24961 agtgcggtgc agaagcatca agcgaaaaca acctccccag agagtgacgg gaggcgatcc
    25021 cggcacacgc tagagcctcc atcacactca gcacgagaca cctgagatcg acgtacatgg
    25081 tggcaaccga ggagcgcgtg gggacgtcga acgtgaaaac ccctgcattg aggattgagg
    25141 agatccatgt cccccgtcca gatcgtccgt accgtagccg ccgccctgat cgccggtggc
    25201 gggaccctcg ggctggtccc tggcggaccg tgcggggcgg gctggtgggc cccatccggc
    25261 ggcgacggag cccactacgg gtggttcgcc ttgggggagg agccgcccaa catgctggcc
    25321 ggtgtgtgca acacggccat ggcaccggtg gggtcgtggg cgatcgcgtt gatcgtggcc
    25381 ggggtgaccc tgctggcagg ggtatggatc accacctcct accggccgaa ggacaaaccg
    25441 agaacgtagg cgcc
//
