LOCUS       NZ_JAMTCR010000009     21101 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Actinokineospora globicatena strain DSM 44256
            LV79DRAFT_scaffold00008.8, whole genome shotgun sequence.
ACCESSION   NZ_JAMTCR010000009
VERSION     NZ_JAMTCR010000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinokineospora globicatena
  ORGANISM  Actinokineospora globicatena
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Actinokineospora.
REFERENCE   1  (bases 1 to 95677)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 95677)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUN-2022) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: AllPaths v. r46652
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 261.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024171945.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 06:43:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,731
            CDSs (total)                      :: 6,666
            Genes (coding)                    :: 6,609
            CDSs (with protein)               :: 6,609
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 8 of 57
            Pseudo Genes (incomplete)         :: 49 of 57
            Pseudo Genes (internal stop)      :: 2 of 57
            Pseudo Genes (multiple problems)  :: 1 of 57
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:43:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 20301
            Orig. end                         :: 41402
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAMTCR010000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21101
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="1"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..21101
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21101
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11101](+)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11101
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     gene            complement(452..1267)
                     /locus_tag="LV79_RS33315"
                     /old_locus_tag="LV79_006574"
     CDS             complement(452..1267)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680994.1"
                     /locus_tag="LV79_RS33315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_006574"
                     /product="peptidase M10A"
                     /protein_id="WP_253842313.1"
                     /transl_table=11
                     /translation="MRRSKTTAALATVLAACAVMLVEQPVADAAGDGELYLVATAYTFD
                     ESGEVHSDDAAAGDANTSAATKAAADTSCSDSTYALKPWKVTTLKWLYNNAGVPAAIAS
                     TALSTITAATDTVAKGANRCGQAANLTSTFTYSGTTSVKPQVATNATCTGNDGKSVTGW
                     GALPAKVLAYTCTYYNARGAVVASDTLIDNVAYTWFTTKPANCTGAKYDLQTTLTHERL
                     HTAGLGHVDQVRNAAQVMTPASSACDTSRRLLGAGDYAGLKALAARATR"
     gene            complement(1373..2179)
                     /locus_tag="LV79_RS33320"
                     /old_locus_tag="LV79_006575"
     CDS             complement(1373..2179)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013395.5"
                     /locus_tag="LV79_RS33320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_006575"
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="WP_253842314.1"
                     /transl_table=11
                     /translation="MGYEPEFLDVALPVPEVDADLVDDVYRLDGSSTLDYTHFSLALST
                     SRRFARWVAWNIDGTAMHRLPRTGIAFTKDPRLPAEIQVGDEVYAGNRLDRGHLARRAD
                     LLWGSLSEAKRANRDSFRFTNITPQVDDFNQSVRQGLWGRLEDALYADVEVDRLRVSVF
                     GGPVLGADDRPYRGVALPREFWKVIASVQSGALRASAFVLTQDLNRVESLEFAEFRVYQ
                     VPIAELEPRAGLRFDPVLTTADTAPPLAQDLAAREPLTSTDQISWS"
     misc_feature    complement(2430..2444)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 24.57"
                     /tool="antismash"
     misc_feature    2431..2445
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     gene            2668..5160
                     /locus_tag="LV79_RS33325"
                     /old_locus_tag="LV79_006576"
     CDS             2668..5160
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686623.1"
                     /locus_tag="LV79_RS33325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_006576"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_253842315.1"
                     /transl_table=11
                     /translation="MKRNSGSPAKSTTTIRSRLTGVVVVPSVILLVMWAVFSSYTVFDG
                     IYLKAVTSGVKDASIPAVDTFAALQRERQLTMTALSTANPDTLALKTQQQTTDKVVGEL
                     RLALDGLSANAPAEVNARVQALNQALAPLPQRRAQVESGRANRDEIYTYYNTVLDAGTA
                     LFDTQARIVPDSVVVQAGLTATDIFRAADRMSRASSLGAAALAAGSFTADQHVEFANLV
                     GSYRATAASASAVGTDEVKAHYQRLTSAESWLRLTAAENALIGAAPRLTDTGNRRAEPL
                     AMPVNPGEWEAVTQSASEELIKLAIEQATGGVELGLQRADDKFFEVIIGSLIALLAVVT
                     GIVLAVRISRRLVNKALVTRLDQLKSDSLQLAHEKLPSIVDRLRQGDRVDVGAEVPPLD
                     YGTDEIGQVADAFNAAQYTAIAAAVKESQAREGVNRVFLGIAHRHQGLVHRQLKILDKM
                     EREEENPEHLDSLFQLDHLATRARRNAENLIILAGEQPGRQWRKPVRLLDILRAAVAET
                     EQYVRVRVRQVPDVALNGVAVADTIHLVAELVDNAASFSPPRSQVEVYTSQVSGGVVVE
                     IEDHGLGMTAEDREQHNQMLAHPPEFDAMALRGESRLGLFVVARLAARRAIRVELRESP
                     YGGTVALVFIPADIVAETPDFVPESDAPSPRPRKALDRAATGAVVDSDTVVELVEPRGG
                     IDKFWSDAVGDDPARAGAEAAHADLWPLTDEEAPDHHPGAGAGNGVGDSHTDNGHRDGA
                     RAADGAPAVRGERPTLPRRQRQQNLAPQLRDEPLLPDWESEPDPPEQGEQTAARVRDTM
                     AAFQRGTKQARRTDGAQQ"
     gene            5187..5654
                     /locus_tag="LV79_RS33330"
                     /old_locus_tag="LV79_006577"
     CDS             5187..5654
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686624.1"
                     /locus_tag="LV79_RS33330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_006577"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_253842384.1"
                     /transl_table=11
                     /translation="MAGTTGKEQPKVNDKIGQDHQLNWLLDDLVRRVVGIRHSVVLSAD
                     GLLLGRSAELSKDDSEHLSAMASAFQSLARGTGRQFGGGQVRQTIVEMDHAFLFVTAAG
                     RGACLAVLGEEDADVGMIAYEMNMLVKRVGAHLASAPRGGAPVTVPGRRPS"
     misc_feature    5225..5239
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            5654..6025
                     /locus_tag="LV79_RS33335"
                     /old_locus_tag="LV79_006578"
     CDS             5654..6025
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942553.1"
                     /locus_tag="LV79_RS33335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_006578"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_092774327.1"
                     /transl_table=11
                     /translation="MSGEADWWFDEAAGPLVRPYAMTRGRTRPNAPNLNLVTQVRVARQ
                     PSDPSTLSPEHLQIIELCTVPLSVAEVAAYLNVPLVVVKVLISDLIERGDVQAGALFQT
                     TEINDTKLLQAVLDGIRRI"
     gene            6006..6602
                     /locus_tag="LV79_RS33340"
                     /old_locus_tag="LV79_006579"
     CDS             6006..6602
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012795743.1"
                     /locus_tag="LV79_RS33340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_006579"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_253842316.1"
                     /transl_table=11
                     /translation="MAFGGSEQVSDAPVVPTSIKIVVAGGFGVGKTTMVNSVSEIPPLR
                     TEEVLTEASVGVDDMRGIEGKETTTVALDFGRITINPQVVLYLFGTPGQNRFWFMWDEL
                     AHGALGAIVLVDTRRLDSSFPSIDFFERRDIPFIIAVNGFEGSWEHTADEVRQALDIAP
                     TVPIINCDARLKDSSKDVLVELVQYTMDLLSKTPV"
     gene            complement(6986..8017)
                     /locus_tag="LV79_RS33345"
                     /old_locus_tag="LV79_006580"
     CDS             complement(6986..8017)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103307.1"
                     /locus_tag="LV79_RS33345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_006580"
                     /product="hemolysin family protein"
                     /protein_id="WP_253842317.1"
                     /transl_table=11
                     /translation="MSTGPALLVSFVLLVANAFFVAAEFALVASKRHRLEEAAAEGSRA
                     ARAAVAGTRELSVMLAGAQLGITLCTLGLGALAKPAVAHLLDPLFSTLGLSPSWSYPIA
                     FVLAVVIVVFLHMVVGEMAPKSWAISHPERSAQWLALPFRAFTRVTRPVLTMLNGLANA
                     TLRAVKVEPQDTVAQAHGPDDLRMLLRESREHGLLPEQQHQILSGVLQVQRTTVGQVMA
                     PRSAMVATPSSATVAEIEDVCRTSGRSRLIVLDDAGEPVGLVHVRDAVRATLAGTAVLA
                     SDLMTEPLVLPADSTAADAVARMRAERAQLALVSTDDQIVGLAALEDLLEEILGEFDDE
                     TDS"
     gene            complement(8014..9363)
                     /locus_tag="LV79_RS33350"
                     /old_locus_tag="LV79_006581"
     CDS             complement(8014..9363)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686630.1"
                     /locus_tag="LV79_RS33350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_006581"
                     /product="hemolysin family protein"
                     /protein_id="WP_253842318.1"
                     /transl_table=11
                     /translation="MLILIGVVSVLLLTAATGYFVAQEFAYVAVDRNRLRQLAEDGDKA
                     AERAYRVTQRLSFMLSGAQFGITVTALLVGYVSEPFLGDGTAALLGLAGLPSGVSTALS
                     IVVALLFSTVVQMVFGELAPKNLAIAKPEALAKSLSRSTLVYLAIAGPLIRMFDTASTK
                     LLRAVGIEPIEELPQGATAEDLRGIIDESRQGGHLDAGTSRLLEGGLDFRTLTAGQVMT
                     PRVDVHLLRADDPAVRVVELLDTGRSRFPVVGADIDDVIGVVGIAEVLTVSPDARASTP
                     VRDIAVAPLYLPDSLPLPEVLERLRAEHRQLACVVDEFGGFAGVVSFEDVAEEVVGEIL
                     DEDDHMEVQAVAHADGSWSVPARWRVDEVAEVTGIELPESAGYDTVSGLVMQRLGRVPR
                     PGDHVEVEVGIADSDLDDGPHKAVVAVTEVHRHVPRTVLVSVRSDAEVPA"
     misc_feature    9547..9559
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     misc_feature    complement(9623..9636)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.79"
                     /tool="antismash"
     misc_feature    9747..9763
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.34"
                     /tool="antismash"
     misc_feature    complement(9764..9779)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     misc_feature    9815..9827
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.38"
                     /tool="antismash"
     gene            10001..11101
                     /locus_tag="LV79_RS33355"
                     /old_locus_tag="LV79_006582"
     CDS             10001..11101
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF023417.5"
                     /locus_tag="LV79_RS33355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_006582"
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_253842319.1"
                     /sec_met_domain="indole_PTase (E-value: 8.8e-95, bitscore:
                     310.1, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRITRSGAVTLNEHTGAQVRRLCAVLGLAEQADEVGAVLADIIGP
                     AGTRALDEPPLWRSDVADDHTPVEYSVAFEEDGTHTLRLLVESVARKPGPTANLAAALS
                     CLDRLAQRYPLALDRFDAVRGLFLPDEPRGVFSLWFSIVVTRSRVAVKIYLNPEVHGQA
                     AAPGLVAAGLDRLGLTAAWPDLSSHAPRPTSTLDRFSFFAIDLDDTPRSRVKVYQSHFR
                     AGLRELTHLGAACPLTDADVLADFDATIGGRESYDGRPLVTSYIYLAGQREPSGFSVYL
                     PVRDYVPDDAVALARTKTLLSAHGFDAAVLDRAIAAVTDRPLESGVGLIAHVSLRMGRP
                     RPGVTVYLSAEAYAVAAPGGVAAGAA"
     misc_feature    10316..10318
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11141..12511
                     /locus_tag="LV79_RS33360"
                     /old_locus_tag="LV79_006583"
     CDS             11141..12511
                     /NRPS_PKS="Domain: Beta_elim_lyase (44-420). E-value:
                     8.6e-74. Score: 240.3. Matches aSDomain:
                     nrpspksdomains_LV79_RS33360_Beta_elim_lyase.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015788005.1"
                     /locus_tag="LV79_RS33360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_006583"
                     /product="tryptophanase"
                     /protein_id="WP_253842320.1"
                     /transl_table=11
                     /translation="MPLMEPYRVKVVEPIPILTRADREAAMARAGYNPFNLRADEITID
                     LLSDSGTGALSAAQQAAGAIGDETYAGSASWFRFREVVDELTGYPHIFPVHQGRAAERI
                     LFNALLEPGQLCVSNTHFDTTRANVLLAGGKPVDLPCAAAADLDSDHPFKGDIDLDALR
                     AALEGPESVGVVVMTITNNGGGGQPVSMANLTAVRDLCREHGVPFFLDAARFAENAWLV
                     VQREPGWSDKTPAEVARAAFELADGAVASLKKDAIAHIGGFLALRDPELAAQCELVLIA
                     TEGFRTYGGLAGRDLEMLAQGLREVVDPRYLAARAAATRYLGDLIKAAGVSIVEPAGIH
                     ALYLNAGRLLTHLPPAQYPGHALATELYLAGGIRCAELGTLYLGEEDENGVLLKAAPYE
                     LVRLAIPRRVYTQSHLEYVAEVVGEIAKNPERVPGYRMVSAPKLLRHFNCRVEPIRA"
     aSDomain        11273..12400
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LV79_RS33360_Beta_elim_lyase.1"
                     /evalue="8.60E-74"
                     /label="LV79_RS33360_Beta_elim_lyase.1"
                     /locus_tag="LV79_RS33360"
                     /protein_end="420"
                     /protein_start="44"
                     /score="240.3"
                     /tool="antismash"
                     /translation="DLLSDSGTGALSAAQQAAGAIGDETYAGSASWFRFREVVDELTGY
                     PHIFPVHQGRAAERILFNALLEPGQLCVSNTHFDTTRANVLLAGGKPVDLPCAAAADLD
                     SDHPFKGDIDLDALRAALEGPESVGVVVMTITNNGGGGQPVSMANLTAVRDLCREHGVP
                     FFLDAARFAENAWLVVQREPGWSDKTPAEVARAAFELADGAVASLKKDAIAHIGGFLAL
                     RDPELAAQCELVLIATEGFRTYGGLAGRDLEMLAQGLREVVDPRYLAARAAATRYLGDL
                     IKAAGVSIVEPAGIHALYLNAGRLLTHLPPAQYPGHALATELYLAGGIRCAELGTLYLG
                     EEDENGVLLKAAPYELVRLAIPRRVYTQSHLEYVAE"
     CDS_motif       11597..11641
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LV79_RS33360_0001"
                     /evalue="6.80E-03"
                     /label="C2_LCL_024-062"
                     /locus_tag="LV79_RS33360"
                     /protein_end="167"
                     /protein_start="152"
                     /score="8.9"
                     /tool="antismash"
                     /translation="FKGDIDLDALRAALE"
     gene            12553..13209
                     /locus_tag="LV79_RS33365"
                     /old_locus_tag="LV79_006584"
     CDS             12553..13209
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017982951.1"
                     /locus_tag="LV79_RS33365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_006584"
                     /product="DUF998 domain-containing protein"
                     /protein_id="WP_253842321.1"
                     /transl_table=11
                     /translation="MAVVTRTGRTGLLWALGGLLGGVAALLALHVLPPTNEISPVRRTI
                     SEYALSDNKWLFDAAIVLIAASSAVGFVELWRRRAHVPTAVLGAIWTLSLLTVVLFTKN
                     DWSVGPSTGGMIHRYASVAAFLSLPSAVLLAAGRAFPAHPAWRWATRTCGALSLLWFST
                     IVIGALNMLTGGQPWWRFVPLGLVERLIAGSAVAGLALLILGLLHLDRRPLPTSP"
     gene            13705..14520
                     /locus_tag="LV79_RS33370"
                     /old_locus_tag="LV79_006585"
     CDS             13705..14520
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS33370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_006585"
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="WP_253842322.1"
                     /transl_table=11
                     /translation="MIEVCTDEAWSPPVVGVYPFGRPAVRRGPRLPRTDRAQAFLLGVY
                     PGALRVRWHRPGGGRVAALAVDDEPDACPTGTDLADRVATWRGAVGWRAEWGTVEVTDP
                     PDAARLVVTEVLDPLGVDPHAVYATHCVPTYFVKSGDRQANAIAEYDRFAATTGLPRAA
                     LHRRPDRRELVHRALRQEGRELLRQLKDADAPLVITLGREAADVFAGLAGTDRVPFRQT
                     GTYGTSHPIPLGARELRWIPLIHPATRRGVGWRNTHTRWALEHSRGGRP"
     gene            14681..17788
                     /locus_tag="LV79_RS33375"
                     /old_locus_tag="LV79_006586"
     CDS             14681..17788
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS33375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_006586"
                     /product="hypothetical protein"
                     /protein_id="WP_253842323.1"
                     /transl_table=11
                     /translation="MERADVKPKAPGASPIRLGRAVNPAAVQRLQRAAGNRAATRLLAQ
                     NLPVQRNADRAGAESDAKFAAVTAEVETKQGVAKAHPAPGTEAAAAAAAATPPQDDKQA
                     QGKTANAERMNAAKPGEFDKAAFVRAVNEAIAAQAPKNLDEADKFGDSGKADAVKGQVQ
                     GQVTQGKQQSAEQIETTTKAPPDTGAAVDKPVTPLAPGRPPPTPAPPNAANTVPDKAPV
                     AATDFSAGPAQVDQQMAQAEVTEDQLVRSNEPEFTGALREKKSAEAHAVTAPGQVRSAE
                     AQTLAGNKSDAAQAGTSAMAAFAGDRAKAGAEVSAGKQGAKSKDEVQRAQVTATLQKVF
                     DAAKSDVETILSELDKKVDDRFTAGEQAVRDAFTAEHKRKMDEYKDKRYSGLFGPAKWI
                     KDKLAGMPEEANRIFDAARQTYVNGMRRVISDVADLIGGELNRAKARIAAGRAELRTAV
                     DSLAPHLRSIGKGAADEFAGKFDELTESVDAKGNDLVHTLASKYNDALKSVDEEIAAEK
                     EKNKGLVAKAVAAVKGVIDTILKLKDLLLGILAKAAAVIAAILRDPIGFLGNLFSAVGA
                     GLRVFLGNIGDHLKRGLVGWLLGAMPAAGVPLPARFDTPGIVTMIATVLGLTWDTIRAR
                     VVRRGVPERAMGAVESAVPEAARLKSDGVGPTLGTALGDVKGHLFGKVAEYLVPTVLVA
                     GITLIVSMLNPASAFIRAIKMIIDFVRFLVENAAQIMAFVNSVLDAVIAIAGGSGGGVP
                     TLIENTLAAGIPLLIGALAALLNLGSVTAKVKSVIQSLSKPVIKAVDRVIDKLVTVGRS
                     ILAKLKRSAPPRSKSPASQHRDPARKDAPARRDSRAPKDTPARKETPASRQRDLAAAMR
                     AAVIAIRNGTSREDVVSHFPAIRLRHRLATLRLHTDRRETHRDYVHAEGTLQRATTTPH
                     PIPVPPSPSPCDTGIALAAKAHASWWKNILSKAKLGDGTQLWNSDVLAGTEAAAVGIAA
                     QADPVPFRATHPRSPFDKAAAIRFFFRHPPSSARHSWTRWAGMQAR"
     gene            17812..18675
                     /locus_tag="LV79_RS33380"
                     /old_locus_tag="LV79_006587"
     CDS             17812..18675
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS33380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_006587"
                     /product="hypothetical protein"
                     /protein_id="WP_253842324.1"
                     /transl_table=11
                     /translation="MSSTAGQAVVDAVGDMTYVVALGPGYGKWDGLPKQRPDPDLKAVV
                     HSMKLLPFLRSMVRERVAGGITWRRFCWLWDHQQGSRDYIKDRFRALDSNMHEWIPTDM
                     IKEVVAGALDHKRLNTVQDGLDWLALHHALRSPTNRVIWQVVANGVIDLGAHPGTFATV
                     ADKKPTLTAGTEDFHKKLRALYRDNKRGTATAFVELLIEMHKADASASVSSHKLIWNGV
                     LTGLAPQLWNAPVDALFKVAPGVFARDITIAWLSDTQVESFKGVGQDFERAKGAIVPER
                     GSAGGP"
     gene            18665..19336
                     /locus_tag="LV79_RS33385"
                     /old_locus_tag="LV79_006588"
     CDS             18665..19336
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS33385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_006588"
                     /product="hypothetical protein"
                     /protein_id="WP_253842325.1"
                     /transl_table=11
                     /translation="MDPEVHNSLTRILGHAAPYEWAEVDRVDSVLVRFAKSVDGLSDLP
                     RLGALVLSAPDVTAIPDLADLPLLSILEVSDSDVTDVRALTTATRLRDVSLLRNKITDL
                     VPVLDCARLESLDVTGNPLSEDSYRRVLAELRDRGVRVVASQEREWRLTLALHAAGLPF
                     SYYLGGDDRHLLSRPGVTRSPYPHVGHINVPPDELEHLLDHDPAGIEPLFDDPDRVLWH
                     L"
     gene            19224..20351
                     /locus_tag="LV79_RS33390"
                     /old_locus_tag="LV79_006589"
     CDS             19224..20351
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013215.5"
                     /locus_tag="LV79_RS33390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_006589"
                     /product="DNA topoisomerase IB"
                     /protein_id="WP_344761079.1"
                     /transl_table=11
                     /translation="MWATSTCRPTNSSTFSTTTPRVSSPCSTIPIECSGTCDQVLSAVA
                     RGIPGLVRLRRSDCGSAGIRRRRVGRGFSYTRDDGRVVTGEEKERIRALAVPPAWGEVW
                     ICPFPTGHIQAVGVDEAGRKQYLYHEQWRVDRDAEKHERVLVLARRLPGVRERIEADLS
                     GRGLTRDRVLAGALRILDRGVFRVGGEEYAEENDSRGVSTLLRGHVVPRNGQLYFEFPA
                     KSGQQRVATIKDPLLGKLIVALRKGKKDDDRLFCHKDGEIRAAEVNERFKEFAGDDFTV
                     KDMRTWTATVLAATEFAAHDGPPSKRAVSAVMKAVAEQLGNTPAMARKSYVDPRVVEAF
                     TDGRTIQTALKRLAGKGPDEIREPLERAVLRLLRT"
     misc_feature    19344..19346
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 ctgcgcggcg gcgcggacga cgtgctcagc aagccgttcg ccgcggccga gctgctggcc
       61 agggtggagg cgctgctgcg cagggccggt gcgggcgcgg gggacgggac cgtggtctac
      121 gacgacggcg aggtccgggt cgacccgcgc acccgcctgg tcgccgtggg cggccgcgag
      181 ctggagctga ccggcaccga gttccgcctg ctcaacgtcc tggtgcgcaa cgcgggcgcg
      241 gcgctgaccc tgtcggacct gctggcctcg gtgtgggacg acccgaccgg catcgcgccg
      301 gaccgggtca agttcgccgt gctccggctg cgccgcaagc tgggctggtc cgggaacggc
      361 tcacccctct cggccgttcg cggggttggt taccgctacc ggccgagagg ggtgaaccgg
      421 gctcgtccgg tcacatccag ctgacgcttc cttaccgggt ggcgcgcgcc gcgagggcct
      481 tgagacccgc gtagtcaccg gcgcccagca ggcggcggga ggtgtcgcag gcggagctgg
      541 cgggggtcat cacctgggcg gcgttgcgga cctggtcgac gtggccgagc ccggcggtgt
      601 gcaggcgctc gtgggtcagc gtggtctgca ggtcgtactt ggcgccggtg cagttcgcgg
      661 gcttggtggt gaaccaggtg taggcgacgt tgtcgatcag ggtgtccgag gccacgaccg
      721 cgccgcgcgc gttgtagtag gtgcaggtgt acgccagcac cttggcgggc agcgcgcccc
      781 agccggtcac ggacttgccg tcgttgccgg tgcaggtggc gttcgtggcc acctgcggct
      841 tgaccgaggt ggtgcccgag taggtgaagg tgctggtcag gttcgcggcc tgcccgcagc
      901 ggttggcgcc cttggcgacg gtgtcggtgg cggcggtgat cgtcgacagc gcggtcgagg
      961 cgatcgcggc gggcacaccg gcgttgttgt agagccactt gagcgtggtg accttccacg
     1021 gcttgagcgc gtaggtcgag tcgctgcacg aggtgtcggc ggcggccttg gtggccgcgg
     1081 aggtgttggc gtcaccggcg gccgcgtcgt cgctgtggac ctcgccggac tcgtcgaagg
     1141 tgtaggcggt ggccaccagg tacagctcgc cgtcaccggc ggcgtccgcg accggctgct
     1201 cgacgagcat cacggcgcag gcagcgagaa cggtggccag tgctgcggtc gtcttgctgc
     1261 ggcgcatcgg aggtcccctt tggctcttgg cttgatggga caagcctcag ccgccggggg
     1321 agcgggccgg gtacgcgtgc gggtgtgttt cgggtgcggt gggaaaccca ggtcaggacc
     1381 aggaaatctg gtcggtggag gtcaacggct cgcgggcggc aagatcctgg gcgagcggcg
     1441 gcgctgtgtc ggcggtggtc aacaccgggt cgaaccgcag tccggccctc ggttcgagct
     1501 cggcgatcgg cacctggtag acccggaact cggcgaactc caggctctcc acccggttca
     1561 ggtcctgcgt cagcacgaac gcgctggccc gcagcgcacc ggactggacg gaggcgatca
     1621 ccttccagaa ctcgcggggt agtgcgacac cgcggtaggg ccggtcgtcg gcgcccagca
     1681 ccggaccgcc gaacacgctg acccgcaacc gatccacctc gacgtccgcg tagagcgcgt
     1741 cctccagcct gccccacagc ccctgccgca cgctctggtt gaagtcgtcc acctgcgggg
     1801 tgatgttggt gaaccggaac gagtcgcggt tggcccgctt ggcctcggac agcgaccccc
     1861 acagcagatc cgcccgccgc gccaggtgcc cccggtcgag tcggttgccc gcgtacacct
     1921 cgtcgccgac ctggatctcc gcgggcagcc gggggtcctt ggtgaacgcg atcccggtgc
     1981 gcggcaaccg gtgcatcgcc gtcccgtcga tgttccacgc cacccacctg gcgaaccgcc
     2041 gcgacgtgct caacgccaac gagaagtgcg tgtagtccag cgtgctcgac ccatcaagcc
     2101 ggtacacatc gtcgaccagg tccgcgtcga cctccggcac cggcagcgcc acgtcgagga
     2161 attccggctc gtaccccatg gcatctcccg tccccacacg cacggtcgca gccgcccgag
     2221 agtgccgttg atcacccccc gttggcaaga ccaccacccc cgccctaccc ccggggatgg
     2281 tgtccacatg accacagggg caacgaggag gtgcgtagtg ctgttgatca cccgccgtgg
     2341 gtgggaccgg gcccccgtct gccctcgggg agggtgtccg catggccgtg ggggcaacgc
     2401 gcagtggtgg gtcgggggat tggtacaggg tggaagcgct cccggtgtgc ggtgtacggg
     2461 tggcctacct gctgttcacc ctcttggtga tcccagcgcg cggacccgtc acttccgctt
     2521 gtgggtgaac cggtacgctt catccttgcg taccgcgtgt gatcgttggc gctgagttag
     2581 attgatcttg aatagatcgg gtctgtcact cgccggggcg ataacccgct tggtggcgtg
     2641 agtggcaacc gacgagtgtg gagagctgtg aagcggaaca gcgggtcgcc cgccaagtcg
     2701 accacgacga tccggtcccg cctcaccggc gtcgtggtgg tgcccagcgt catcctgttg
     2761 gtgatgtggg cggtcttctc gtcctacacc gtcttcgacg gcatctacct caaggccgtg
     2821 accagcggcg tgaaggacgc ctcgatcccc gcggtcgaca ccttcgccgc gctgcagcgc
     2881 gagcgccagc tgaccatgac cgcgctgagc accgccaacc cggacacgct cgcgctcaag
     2941 acccagcagc agaccaccga caaggtcgtc ggcgagctgc ggttggcgct cgacggcctc
     3001 tccgccaacg cccccgccga ggtcaacgcc cgggtccagg cgctcaacca ggcgctggcc
     3061 ccgctgccgc agcggcgcgc gcaggtcgag tccggccggg ccaaccgcga cgagatctac
     3121 acctactaca acaccgtgct cgacgccggt accgcgctgt tcgacaccca ggcgcgcatc
     3181 gtgcccgact cggtcgtcgt gcaggccggt ctgaccgcca ccgacatctt ccgcgccgcc
     3241 gaccgcatgt cgcgcgcctc ctcgctcggc gccgccgcgc tcgccgcggg ctcgttcacc
     3301 gccgaccagc acgtcgagtt cgccaacctg gtcggctcct accgggccac cgccgcctcc
     3361 gcgtccgccg tcggcaccga cgaggtcaag gcccactacc agcggctgac cagcgccgag
     3421 tcctggctgc ggctgaccgc ggcggagaac gcgctcatcg gcgccgcgcc ccggctcacc
     3481 gacaccggca accgccgcgc cgaaccgctg gccatgccgg tcaacccggg ggagtgggag
     3541 gcggtcaccc agagcgcgtc cgaggagctg atcaagctcg ccatcgagca ggccaccggc
     3601 ggtgtggagc tgggcctgca gcgcgcggac gacaagttct tcgaggtgat catcggtagc
     3661 ctcatcgcgc tgctcgccgt ggtcaccggc atcgtgctcg ccgtgcgcat ctcgcgcagg
     3721 ctggtcaaca aggccctcgt gacccggctc gaccagctca agagcgactc gctgcaactg
     3781 gcgcacgaga agctgcccag catcgtcgac cggctccgcc agggcgaccg ggtcgacgtc
     3841 ggcgccgagg tccccccgct cgactacggc accgacgaga tcggccaggt ggccgacgcg
     3901 ttcaacgccg cccagtacac cgccatcgcc gccgcggtga aggagagcca ggcccgcgag
     3961 ggcgtcaacc gcgtcttcct cggcatcgcg caccgccacc agggcctggt ccaccgccag
     4021 ctcaagatcc tggacaagat ggagcgcgag gaggagaacc cggagcacct cgactccctg
     4081 ttccagctcg accacctcgc cacccgcgcc cgccgcaacg ccgagaacct gatcatcctc
     4141 gccggtgagc agccgggtcg gcagtggcgc aaaccggtgc ggctgctcga catcctgcgc
     4201 gccgcggtcg ccgagaccga gcagtacgtc cgggtccggg tccgccaggt gcccgacgtg
     4261 gcgctcaacg gcgtcgccgt cgccgacacc atccacctgg tcgccgaact cgtcgacaac
     4321 gcggcctcgt tctccccgcc gcgctcgcag gtcgaggtct acaccagcca ggtctccggc
     4381 ggtgtcgtcg tcgagatcga ggaccacggc ctcggcatga ccgccgagga ccgcgagcag
     4441 cacaaccaga tgctggcgca cccgccggag ttcgacgcga tggcgctgcg cggcgagtcc
     4501 cgcctcggcc tgttcgtggt cgcccggctg gccgcgcgcc gcgcgatccg ggtcgagctg
     4561 cgcgagtcgc cctacggcgg caccgtggcc ctggtgttca tccccgccga catcgtcgcc
     4621 gagaccccgg acttcgtgcc ggagtccgac gcgccgagcc cccgcccgcg caaggcgctc
     4681 gaccgggccg ccaccggcgc cgtggtcgac agcgacaccg tcgtggagct ggtggagccg
     4741 cgcgggggca tcgacaagtt ctggtccgac gccgtggggg acgaccccgc cagggcgggg
     4801 gccgaggcgg cgcacgcgga tctgtggccg ctgaccgacg aggaggcccc ggaccaccac
     4861 ccgggcgccg gtgccgggaa cggggtgggg gactcgcaca cggacaacgg gcaccgcgac
     4921 ggtgccaggg ccgcggacgg cgcaccagcc gtgcgcggtg agcgcccgac gctgccgcgc
     4981 aggcagcgcc agcagaacct cgcgccgcag ctgcgcgacg aaccgctgct gccggactgg
     5041 gagagcgagc ccgacccgcc ggagcagggc gagcagaccg cggccagggt gcgcgacacg
     5101 atggccgcct tccagcgcgg cacgaagcag gcgcgcagga ccgatggagc acagcagtga
     5161 accccccggg tgcggcggcg gggttgatgg cggggacgac ggggaaggaa cagcccaagg
     5221 tgaacgacaa gatcggccag gaccaccagc tgaactggct tttggacgac ctggtccgcc
     5281 gggtcgtggg gatccgccac tcggtcgtgc tctccgcgga cggactgctg ctcggccgct
     5341 cggccgagct gtccaaggac gactccgagc acctgtcggc gatggcctcg gcgttccaga
     5401 gcctggccag gggcaccggc cgccagttcg gcggcggcca ggtccgccag acgatcgtcg
     5461 agatggacca cgcgttcctg ttcgtcaccg cggcgggccg cggtgcctgc ctcgccgtgc
     5521 tcggagagga ggacgcggac gtcgggatga tcgcctacga gatgaacatg ctggtcaagc
     5581 gggtcggcgc gcacctggcc tcggctccgc gcggcggcgc gccggtcacg gtccccggcc
     5641 gtcggccctc gtgatgtccg gcgaggcgga ctggtggttc gacgaggcgg ccggacccct
     5701 ggtccgcccg tacgcgatga ccagggggcg cacccggccg aacgcgccca acctgaacct
     5761 cgtcacccag gtccgggtag cccgccagcc gtcggacccc tcgaccctgt ccccggagca
     5821 cctgcagatc atcgagctct gcacggtccc gctctcggtg gccgaggtcg ccgcctacct
     5881 caacgtcccg ctcgtggtgg tcaaggtcct catcagcgac ctgatcgaac gcggcgacgt
     5941 gcaggcaggc gcgttgttcc agaccaccga gatcaacgac acgaagttgc tccaagcggt
     6001 actcgatggc attcggagga tctgaacagg tgagcgacgc cccggtggtc cccacctcca
     6061 tcaagatcgt cgtagctggc ggcttcggcg tcggcaagac gaccatggtc aactcggtca
     6121 gcgagatccc gccgctgcgc accgaggaag tcctgaccga ggccagcgtc ggcgtcgacg
     6181 acatgcgcgg catcgagggc aaggagacca ccacggtcgc cctggacttc ggccgcatca
     6241 ccatcaaccc gcaggtcgtg ctgtacctgt tcggcacccc gggccagaac cgcttctggt
     6301 tcatgtggga cgaactggcc cacggcgccc tcggcgccat cgtcctggtc gacacccgca
     6361 ggctcgactc cagcttcccc tcgatcgact tcttcgaacg ccgcgacatc ccgttcatca
     6421 tcgcggtcaa cggcttcgag ggctcctggg agcacaccgc cgacgaggtc cgccaagccc
     6481 tcgacatcgc ccccaccgtc cccatcatca actgcgacgc ccgcctcaag gactccagca
     6541 aggacgtcct cgtcgaactc gtccagtaca cgatggacct gctcagcaaa accccggtct
     6601 gacctgccct tctccggttt ccccaccccg ccgatttccg tcttccgggt gacaggagtt
     6661 atccacatgt ggatctccag cggggtgctt tcaagatcca ctgtcggtgg gccccagtag
     6721 actggccctg gggccgcccc ccggggaggg tgggggcagg ggcaggctcg ggtggggcgg
     6781 gcggggctgt caagggggtt tgctcgaagg tgtgacggcg ggggcgcgga gaccacgcga
     6841 tcgcgagagc cgccggaact tggtgagtcc actgtggacg aaagcgacgg gtcggtcggt
     6901 tcgtgcctcg accggggctt gggacgtggc gcggcccgag ggtggggaac cacgctcggg
     6961 ccgcgatccg gggctggatc cggtgctagg agtccgtctc gtcgtcgaac tcgccgagga
     7021 tctcctcgag gaggtcttcc agggcggcga ggccgacgat ctggtcgtcg gtcgacacca
     7081 gtgccaactg ggcgcgctcg gcgcgcatcc gggcgaccgc gtccgcggct gtcgagtcgg
     7141 cggggagcac cagcggttcg gtcatgaggt cgctggccag cacggcggtc ccggccaggg
     7201 tcgcgcgcac ggcgtcgcgc acgtgcacca ggccaacagg ttccccggcg tcgtccagca
     7261 cgatcagccg ggagcggccg ctggtccggc acacgtcctc gatctcggcc accgtcgccg
     7321 acgacggcgt tgcgaccatc gccgagcggg gagccatgac ctggccgacg gtggttcgtt
     7381 gcacctgcag cacgccggac aggatctggt gctgctgctc gggcaacagg ccgtgctcgc
     7441 gcgactcccg cagcaacatc cgaagatcgt ccgggccgtg tgcctgggcc acggtgtctt
     7501 gcggctcgac cttcaccgcg cgcaacgtgg cgttggccag gccgttgagc atggtcagca
     7561 ccgggcgggt gacccgggtg aacgcgcgga acggcagcgc cagccactgc gccgagcgct
     7621 ccgggtgcga gatcgcccag gacttcgggg ccatctcgcc gaccaccatg tgcaggaaga
     7681 cgacgatcac cacggccagc acgaacgcga tcgggtagct ccacgacggc gacagcccga
     7741 gggtgctgaa cagcgggtcg agcaggtgcg cgacggcggg cttggccaac gcgcccagac
     7801 ccagcgtgca cagggtgatc cccagctgcg cgcccgccag catcaccgac agctcacggg
     7861 tccccgcgac cgcggcccgc gcggcgcggc tgccctcggc cgccgcttcc tccaaccggt
     7921 gccgcttgct cgccacgagt gcgaactcgg cggccacgaa gaacgcgttc gccaccagca
     7981 gcacgaacga caccagcaac gccggtccgg tgctcacgcg ggtacctccg cgtccgagcg
     8041 gaccgacacc agcaccgtgc gcggcacgtg ccggtgcacc tcggtgaccg cgacgaccgc
     8101 cttgtgcgga ccgtcgtcga ggtccgagtc tgcgatgccg acctccacct ccacgtggtc
     8161 accggggcgc ggcacccgac cgaggcgctg catgaccagc ccgctgacgg tgtcgtagcc
     8221 cgcgctctcg ggcagttcga tcccggtcac ctcggcgacc tcgtcgaccc gccaccgcgc
     8281 gggcaccgac cacgagccgt ccgcgtgcgc gaccgcctgg acctccatgt ggtcgtcctc
     8341 gtccaggatc tcgccgacga cctcctcggc gacgtcctcg aaggacacca cgcctgcgaa
     8401 cccgccgaac tcgtcgacca cgcaggccag ttggcggtgc tcggcgcgca gccgctccag
     8461 cacctcgggc agcggcaggc tgtcgggcag gtacagcggc gccacggcga tgtcgcgcac
     8521 cggggtgctc gcgcgcgcgt ccggggacac ggtcagcacc tccgcgatgc cgaccacgcc
     8581 gatcacgtcg tcgatgtcgg cgcccaccac cgggaaccgg gaccggccgg tgtcgagcag
     8641 ctcgaccacc cgcaccgccg ggtcgtcggc gcgcagcagg tgcacgtcga cccgcggcgt
     8701 catgacctgg cccgcggtga gggtgcggaa gtcgagtccg ccctccagca gccgcgaggt
     8761 gcccgcgtcg aggtgaccgc cctggcgcga ctcgtcgatg atgccgcgca ggtcctccgc
     8821 cgtcgcgccc tgcggcagct cctcgatcgg ctcgatgccg accgcgcgca gcagcttggt
     8881 cgaggcggtg tcgaacatcc ggatcagcgg cccggcgatc gccaggtaca ccagcgtgga
     8941 ccggctcagc gatttggcca gcgcctcggg cttggcgatc gccaggttct tgggggcgag
     9001 ctcgccgaag accatctgca ccacggtgga gaacagcagc gcgaccacga tggacagcgc
     9061 ggtgctcacc ccgctgggca acccggcgag gccgagcagc gcggcggtgc cgtcgccgag
     9121 gaacggctct gacacgtagc cgaccagcag cgcggtgacg gtgatgccga actgggcgcc
     9181 ggagagcatg aacgagagcc gctgggtcac ccggtacgcg cgctcggcgg ccttgtcgcc
     9241 gtcctcggcg agctggcgca accggttgcg gtcgaccgcg acgtaggcga actcctgggc
     9301 gacgaagtac ccggtcgccg cggtgagcag caggaccgag accacaccta tgaggatcag
     9361 caccggctct ccggggcggc cacgccgggg cggcgggagg ggcggatcag tggccgggcg
     9421 ctacccggcc cgcgactgca gccgtcggtg gaacacatgc gaacaacgct aacacgatgt
     9481 ccgattcacc gttgtgccga cgaggtaggg gctgtccatc atggactctt cgacgagttg
     9541 gccggggtgc cgctgtcaag cagactcccc gatcggacca tcggatgtct cacgtgacgc
     9601 acatcgcttt cccgtgctcc gcccacgcag cgtcacgggt gcgcgcacgt gcgtccgcac
     9661 gggcgcgcag tcgtccagac cgcgccggag cccgcgtcgc ggctgtaagc actgctcagt
     9721 cgatctcgga cggggtacgg ccgaattggt aagtttttca cgaagtgaat tgcttcacat
     9781 gaaatcggtc gctttttcgc gaccctccgt gcctgtggca ttgtcactag cacggcgtcc
     9841 acaatccggc aacggcggtt ttcggcagct cttctcattt accctctgta agagcgcgtt
     9901 cggagtggat caccgcgttg gcggtactgg cttgttcgta ttcacccgta cgttgcctgg
     9961 tgtcgtcggt gtgggtgaat ggctgggtag gggtctgcac gtgaggatca cgcggtcggg
    10021 ggcggtcacg ctcaacgaac acaccggggc ccaggtgcga cggttgtgcg ccgtgctcgg
    10081 tctggccgaa caggccgacg aggtcggtgc cgtgctcgcc gacatcatcg gccccgcggg
    10141 taccagggcg ctcgacgagc cgccgctgtg gcgctccgat gtggccgatg accacacgcc
    10201 cgtcgagtac tccgtggcgt tcgaagagga cggtacgcac acgctgcggc tgctggtgga
    10261 gtcggtggcg cgcaagccgg ggccgacggc caacctcgcc gccgcgctgt cctgcttaga
    10321 ccgtctggcg cagcgctacc cgttggcgct ggaccgcttc gacgccgtgc gcgggctgtt
    10381 cctgcccgat gagccgcgcg gggtgttctc gctgtggttc tccatcgtcg tcaccaggtc
    10441 cagggtcgcg gtgaagatct acctcaaccc ggaggtgcac ggccaggccg ccgcgcctgg
    10501 gctggtcgcc gccgggctcg accggctcgg cctcaccgcc gcgtggcccg acctgagctc
    10561 gcacgcgccg cgcccgacgt ccacattgga ccggttctcg ttcttcgcca tcgacctcga
    10621 cgacacgccg cgctcgcggg tcaaggtgta ccagagccac ttccgcgcag gcctgcgcga
    10681 gctgacccac ctcggggccg cctgcccgct caccgatgcc gacgtgctcg ccgacttcga
    10741 cgcgaccatc ggcggccgcg agagctacga cggcaggccg ctggtgacca gctacatcta
    10801 cctggccggg cagcgcgaac cgagcgggtt ctcggtctac ctgccggttc gcgactacgt
    10861 gcccgacgac gccgtggcgc tggcgcggac caagacgctg ctctccgcgc acggcttcga
    10921 cgccgccgtg ctcgaccggg ccatcgccgc ggtcaccgac cgtccacttg agtccggggt
    10981 cgggctgatc gcgcacgtct cgctgcgcat gggccgcccg cgccccggtg tcaccgtcta
    11041 cctctccgcg gaggcctatg ccgtcgccgc ccccggcggg gtcgcggcgg gcgcggcata
    11101 aaccagggaa aacctcaagg aaaaaggacg taaactgccg atgccgctca tggagccgta
    11161 ccgcgtcaag gtcgtcgagc ccattcccat cctcaccagg gccgaccgcg aggcggcgat
    11221 ggccagggcc ggttacaacc cgttcaacct gcgcgccgac gaaatcacga tcgacctgct
    11281 cagcgattcc gggaccggcg cgctctcggc cgcgcaacag gcggctggcg cgatcggcga
    11341 cgagacctac gcgggttcgg cgtcgtggtt ccgcttccgc gaggtcgtcg acgagctcac
    11401 cgggtacccg cacatcttcc cggtccacca agggcgcgcg gccgagcgga tcctgttcaa
    11461 cgcgctgctc gagccgggcc agttgtgcgt gagcaacacc cacttcgaca ccacccgggc
    11521 caacgtcctg ctcgcgggcg gcaagccggt cgacctgccg tgcgcggccg ccgccgacct
    11581 cgacagcgac cacccgttca agggcgacat cgacctcgac gcgctgcggg ccgcgctgga
    11641 gggtcccgag tcggtcggcg tggtcgtcat gacgatcacc aacaacggcg gcggcggaca
    11701 gccggtgtcc atggccaacc tgaccgcggt gcgcgacctg tgccgcgagc acggggtgcc
    11761 gttcttcctc gacgccgccc gcttcgccga gaacgcgtgg ctggtcgtgc agcgggagcc
    11821 gggctggtcg gacaagaccc cggccgaggt cgccagggcc gcgttcgagc tcgccgacgg
    11881 tgccgtggcg tcgctgaaga aggacgccat cgcccacatc ggcgggttcc tcgcgctgcg
    11941 cgaccctgag ctggccgccc agtgcgagct ggtgctcatc gccaccgagg ggttccgcac
    12001 ctacggcggc ctggccgggc gcgacctgga gatgctggcg cagggcctgc gcgaggtcgt
    12061 cgacccccgc tacctcgccg cgcgcgccgc cgcgacccgc tacctcggtg acctcatcaa
    12121 ggccgcgggc gtgtccatcg tcgaaccggc gggcatccac gccctctacc tcaacgcggg
    12181 gcggctgctg acccacctgc cgcccgccca gtaccccggg cacgcgctgg ccaccgagct
    12241 ctacctcgcg ggcggcatcc ggtgcgccga gctgggcacg ctgtacctgg gggaggagga
    12301 cgagaacggg gtgctgctca aggccgcgcc gtacgaactc gtccggctcg ccatcccgcg
    12361 ccgggtctac acgcagagcc acctggagta cgtggccgag gtggtggggg agatcgccaa
    12421 gaaccccgag cgggtccccg ggtaccggat ggtgtccgcg ccgaagctgc tgcgccactt
    12481 caactgccgg gtcgagccga tccgggcata gttctcagtt cgcccacagg gtccgtccct
    12541 accctggtcc gcatggctgt ggtcacgcgg acgggacgga ccggactcct gtgggcgctc
    12601 ggggggctgc tcggtggtgt cgcggcgctg ctggcgctgc acgtgctgcc gccgaccaat
    12661 gagatcagcc cggtccggcg caccatcagc gagtacgccc tcagcgacaa caagtggctc
    12721 ttcgacgccg cgatcgtgct gatcgccgcc tcctccgccg tgggcttcgt ggaactgtgg
    12781 cgccgccgcg cgcacgtgcc caccgccgtc ctcggcgcca tctggacact cagcttgctc
    12841 accgtcgtcc tgttcaccaa gaacgactgg tcggtaggcc ccagcaccgg cggcatgatc
    12901 caccgctacg ccagcgtcgc cgcgttcctg tcgctcccct cggccgtcct cctcgccgcg
    12961 ggccgcgcct tcccagccca ccccgcctgg cgctgggcca cccgcacctg cggcgccctc
    13021 tccctgctct ggttcagcac catcgtcatc ggcgccctca acatgctcac cggcggccaa
    13081 ccctggtggc gcttcgtccc cctcggcctc gtcgaacgcc tcatcgcagg ctccgccgta
    13141 gcaggcctcg ccctcctcat cctcggcctc ctccacctgg accgccgccc cctccccacc
    13201 tctccctaac cccacccaga cctccgccat ccccccatcc cgagttatcc ccaacccccc
    13261 acctcatccc cacccaccac ctcatccatt ccccacccgc caccccaccc ggcaggctgt
    13321 atatcggggg cacttcatcc ggttcgatca tgaaccgctc acctggcctc cccgacgcgc
    13381 gtcccggttg gccacagctc cgcgccacca ccccggtctc tccacagccg cccccgcccc
    13441 acgtcgattc gaccttgaac ccaccgccgg acccagatca ccccccatcc ggccccagtt
    13501 gtccccaacc ccccgacctg cccacagccg ccacctcacc cattccccgc ccgccgcacc
    13561 ccctggcagg ctgtatatcg ggggctgctc agcgcggttc gatcatggtc tcgccgcgtc
    13621 ggaccggtgg gttgcgccat cccgaccagc ggcaggtcgt gcgggtggtg tcacgtctga
    13681 cgtccgaccg gcgatacggt cttcgtgatc gaagtctgta ccgatgaagc ctggtcaccg
    13741 ccggtggtcg gggtgtaccc gttcggccga ccggcggtgc ggcgcgggcc tcggctgccg
    13801 cggaccgatc gcgcccaggc gttcctgctc ggcgtctacc ccggcgcgct gcgggtccgg
    13861 tggcaccggc ccgggggcgg gcgggtcgcc gcgctcgccg tcgacgacga gcccgacgcc
    13921 tgcccgaccg gcaccgacct ggccgaccgg gtcgcgacgt ggcgcggtgc cgtcgggtgg
    13981 cgcgccgagt ggggcaccgt ggaggtcacc gacccgcccg acgccgcgcg cttggtcgtc
    14041 accgaggtcc tcgacccgct cggcgtcgac ccccatgccg tctacgccac ccactgcgtc
    14101 cccacctact tcgtcaagtc cggcgaccgc caggccaacg ccatcgccga gtacgaccgc
    14161 ttcgccgcga ccaccggcct gccccgcgcc gccctgcacc gccgccccga ccgccgcgaa
    14221 ctcgtccacc gcgccctgcg ccaagagggc cgcgaactcc tgcgccaact caaggacgcc
    14281 gacgcccccc tggtgatcac cctcggccgc gaggccgccg acgtcttcgc tggcctggcg
    14341 ggcaccgacc gcgtcccctt ccggcagacc ggcacatacg gcacctccca ccccatcccc
    14401 ctcggcgccc gcgaactccg ctggatcccc ctcatccacc ccgccacccg ccgcggcgtc
    14461 ggctggcgca acacccacac ccgctgggca ctcgaacaca gccgcggcgg ccgaccgtaa
    14521 gtgccacaag gggtccatgc ctgcccgtgc gggaagcggt gatcgtccga ccacccggcc
    14581 tcgcgccctg tccttgatcc acccgagtcc cccagactga agccggtgcc gctccagttc
    14641 ggggggacgc gtgaaaacac ctgccgaggg tgcgcaggcg gtggaacggg cggatgtcaa
    14701 gcccaaagcc cctggcgcga gcccgatccg gttgggcagg gccgtcaacc ccgctgcggt
    14761 gcaacggttg cagcgggccg ctgggaaccg cgccgcgacc cggctgctgg cgcaaaacct
    14821 ccccgtgcaa cgcaacgcgg accgcgccgg tgcggaatcc gacgccaagt tcgccgccgt
    14881 caccgccgag gtcgagacca agcagggtgt ggcgaaagcc catccggcac cgggtaccga
    14941 ggcggccgct gccgctgccg ccgcgacacc gccgcaggac gacaagcagg cgcaggggaa
    15001 gacggccaac gcggagagga tgaacgccgc gaagccaggg gagttcgaca aggcggcgtt
    15061 cgtgcgcgcg gtcaacgagg ccatcgccgc gcaggcaccc aagaacctcg acgaggccga
    15121 caagttcggc gactccggca aggccgacgc cgtcaagggg caggtccaag gacaggtcac
    15181 ccagggcaag cagcagtcgg ccgagcagat cgagacgacc accaaggcgc caccggacac
    15241 cggtgcggcc gtagacaaac ccgtcacccc gctcgccccc ggccggccgc cgcccactcc
    15301 ggcacccccc aacgcggcga acaccgtacc cgacaaggcg cccgtcgcgg ccaccgactt
    15361 ctccgccggt cccgcccagg tcgaccagca gatggcgcag gcggaggtca ccgaggacca
    15421 actcgtcagg tccaacgagc ccgagttcac cggtgcgttg cgggagaaga agtccgcgga
    15481 ggcgcacgcc gtgacagcac ccggtcaggt gcgttcggcg gaggcgcaaa cgttggcggg
    15541 caacaaatcc gacgccgccc aggccggaac gtcagcgatg gcggcgttcg ccggagaccg
    15601 ggccaaggcc ggtgccgagg tctcggcggg caagcagggc gccaagagca aagacgaggt
    15661 ccagcgcgca caggtcaccg cgaccctgca gaaggtcttc gacgccgcga agtccgatgt
    15721 ggagaccatt ttgtccgaat tggacaagaa ggtcgatgac cggttcaccg caggggagca
    15781 ggcggtccgc gacgcgttca ccgccgagca caagcgcaag atggacgagt acaaagacaa
    15841 gcggtactcc gggttgttcg gcccggccaa gtggatcaag gacaagctcg ccgggatgcc
    15901 cgaggaggcg aaccggatct tcgacgcggc caggcagacc tacgtcaacg gcatgcggcg
    15961 tgtcatctcc gacgtcgccg acctgatcgg tggcgagctc aaccgcgcca aggcccgtat
    16021 cgcggcgggc cgggccgaac tgcgcaccgc cgtcgactcg ctcgcgccgc acctgcgctc
    16081 gatcggcaag ggggcggccg acgagttcgc cgggaagttc gacgagctca ccgagtcggt
    16141 cgacgccaag ggcaacgacc tcgtgcacac gctggcgtcg aagtacaacg acgcgctcaa
    16201 gtccgtcgac gaggagatcg cggccgagaa ggagaagaac aaggggctgg tcgccaaggc
    16261 cgttgccgcg gtcaagggcg tcatcgacac catcctcaag ctcaaggacc tgctgctcgg
    16321 catcctcgcc aaggccgccg cggtgatcgc ggccatcctg cgcgacccga tcggcttcct
    16381 gggcaacctg ttcagcgcgg tcggtgccgg gctgcgcgtg ttcctcggca acatcggcga
    16441 ccacctcaag cgcggcctgg tcggctggct cctcggcgcc atgcccgccg ccggtgtgcc
    16501 gctgcccgcc aggttcgaca ccccgggcat cgtcaccatg atcgcgacgg tgctcgggct
    16561 gacctgggac accatccgcg cccgggtggt gcgccgcggc gtgccggagc gggcgatggg
    16621 cgcggtcgag tcggcggtcc ccgaggcggc ccggctcaag tccgacggcg tcggcccgac
    16681 cctggggacc gcgctcgggg acgtcaaggg gcacctgttc ggcaaggtcg ccgagtacct
    16741 ggtgccgacc gtgctggtcg cgggcatcac gctgatcgtc agcatgctca acccggcgtc
    16801 ggcgttcatc cgggccatca agatgatcat cgacttcgtc cggttcctgg tcgagaacgc
    16861 cgcccagatc atggccttcg tcaactccgt cctcgacgcc gtcatcgcca tcgcgggcgg
    16921 cagcggcggc ggcgtcccca ccctcatcga gaacaccctc gccgcgggca tcccgctgct
    16981 catcggcgcc ctggccgccc tcctcaacct cggcagtgtc accgccaagg tcaagtccgt
    17041 catccagtcc ctcagcaaac ccgtcatcaa ggccgtcgac cgcgtcatcg acaaactcgt
    17101 caccgtcggc cgctcgatcc tggccaagct caagcgctcc gcgccgccca ggtccaagtc
    17161 ccccgcatcc cagcaccgcg accccgcgcg caaggacgcc cccgcacgta gggacagccg
    17221 cgcacccaag gacacccctg cgcgcaagga gaccccagcg tccaggcaac gcgacctcgc
    17281 cgccgccatg cgcgccgccg tcatcgccat ccgcaacggc accagccgcg aggacgtcgt
    17341 ctcccacttc cccgccatcc gcctgcgcca ccgcctggcc acactccgcc tgcacaccga
    17401 ccgccgcgaa acccaccgcg actacgtcca cgccgaaggc accctccaac gcgccaccac
    17461 caccccgcac cccatacccg tcccgccgtc ccccagcccc tgcgacaccg gcatcgccct
    17521 cgccgccaaa gcccacgcgt cctggtggaa gaacatcctc tccaaggcga agctcggcga
    17581 cggcacgcag ctgtggaact ccgatgtcct cgccgggacc gaggcggccg ccgtgggaat
    17641 cgccgctcaa gccgatcccg tcccatttcg ggcgacccac ccgagatcgc cgttcgacaa
    17701 agcggccgcg atccggttct tcttccgcca tcctccgtcg agcgcaagac attcctggac
    17761 gcgctgggcg gggatgcagg cgcgctgaag aacatgaagg acccggcgag gatgtcgtcg
    17821 accgcggggc aggcggtggt ggacgccgtc ggggacatga cctatgtcgt ggcgctcggc
    17881 cccggttacg ggaagtggga cggccttccg aaacaacggc ctgacccgga tctcaaagca
    17941 gttgtccaca gcatgaagct gctcccgttc ctgcggtcga tggtccggga acgggtggcc
    18001 ggggggatca cctggcggcg gttctgctgg ttgtgggacc accagcaggg cagtcgggac
    18061 tacatcaagg accggttccg cgcgctcgac agcaacatgc acgagtggat cccgacggac
    18121 atgatcaagg aggtcgtggc gggcgccctc gaccacaagc ggctgaacac cgtgcaggac
    18181 ggcctggact ggctggcgct gcaccacgct ctccggtcgc cgaccaaccg ggtgatctgg
    18241 caggtggtcg ccaacggggt gatcgacctg ggtgcgcacc cggggacatt cgccaccgtg
    18301 gctgacaaga aacccacgtt gaccgcggga acggaagatt tccacaagaa gctccgcgct
    18361 ctgtaccggg acaacaagcg gggaactgcc acggcctttg tcgaattgtt gatcgagatg
    18421 cacaaggcgg acgccagtgc tagcgtctcc agccataaac tgatctggaa tggcgtgctg
    18481 accgggttgg cgccgcagtt gtggaacgcg ccggtggacg cactgttcaa ggtggcgcca
    18541 ggagtgttcg cgcgggacat caccatagcg tggctgtctg atacccaggt cgaatcattc
    18601 aagggtgtgg gacaggattt cgagagggca aagggtgcga tcgtccccga gagaggatca
    18661 gcaggtggac cctgaggtgc acaactcgct cacccggata ctcggacacg cggcgccgta
    18721 cgagtgggcc gaagtggatc gcgtcgactc ggtgctggtg cggttcgcca agtcggtgga
    18781 cgggctgtcc gacctcccgc ggttgggcgc gctggtcctg tccgcccccg atgtgaccgc
    18841 gatcccggac ctcgcggact tgccgctcct ctcgatcctg gaggtctccg acagcgacgt
    18901 caccgatgtg cgggcactca ccacagccac tcgcctccgg gatgtctccc tgctcaggaa
    18961 caagatcacc gacctcgtgc cggtcctgga ctgcgcccgc ctcgaatcct tggacgtcac
    19021 cggcaacccg ctgtcggagg actcttaccg ccgtgtcctg gccgaactgc gcgacagggg
    19081 ggttcgggta gtcgcatccc aggaacggga gtggaggctg actctggccc tgcacgccgc
    19141 gggccttccg ttctcctatt acctgggcgg cgacgacagg cacctgttgt cccgccccgg
    19201 cgtgacccgc agcccgtacc cgcatgtggg ccacatcaac gtgccgcccg acgaactcga
    19261 gcaccttctc gaccacgacc ccgcgggtat cgagcccttg ttcgacgatc ccgatcgagt
    19321 gctctggcac ctgtgaccag gttttatccg ctgtggcccg gggaataccg gggctcgtgc
    19381 ggttgcggcg tagtgattgt gggtccgcgg ggattcggcg gaggcgggtg gggcgggggt
    19441 tctcgtacac ccgggatgac gggcgggtgg tgacggggga ggagaaggag cggatccggg
    19501 cgttggcggt gccgcctgct tggggggagg tgtggatctg tccgtttccg acggggcaca
    19561 tccaggctgt gggggtggat gaggcggggc gcaagcagta cctgtaccac gagcagtggc
    19621 gggtggatcg ggacgcggag aagcacgagc gggtgttggt gttggcgcgg cggttgccgg
    19681 gggtgcggga gaggatcgag gccgatctat ccgggcgggg gttgaccagg gatcgggttc
    19741 tggcgggtgc cttgcgcatc ctggaccggg gtgtgttccg ggtcgggggt gaggagtacg
    19801 cggaggagaa cgattcgcgt ggggtgtcga cgctcctgag aggacatgtg gttccgcgca
    19861 acggccagct gtacttcgag ttcccggcca agagcgggca acagcgtgtc gccacgatca
    19921 aagacccgtt gctgggcaag cttatcgtcg ccctgcgcaa gggcaagaag gacgacgacc
    19981 ggctgttttg ccacaaagac ggggaaatcc gggccgcgga ggtcaacgag cggttcaagg
    20041 agttcgcggg ggacgacttc accgtcaagg acatgcggac ctggactgcc accgtgttgg
    20101 ccgccaccga gttcgccgcc cacgatgggc cgccgagcaa gcgcgcggtc tcggccgtga
    20161 tgaaggcggt cgccgagcag ttgggcaaca cccccgccat ggccaggaag tcctatgtgg
    20221 acccaagggt ggtcgaggcg ttcaccgacg gccgcacgat ccagaccgcg ctcaagcggc
    20281 tcgccgggaa ggggccggac gagatccggg agccgctcga gcgggcggtc ctacggctcc
    20341 tgcgtacctg agtcgcccgc cttggtgcgg cggcgcggct cccggcccgg cggggcggac
    20401 ggcgtgggga agtccggggg agcggggatc ggcagcgtca cctcgccgtc gaccacgacc
    20461 ggggagccgt ggtggctggt gtgcacgggg tcgccggaga tcagccggta ggtggcctcc
    20521 tcgccggtga tctcgacctg cagccggctg ccctggaagc acatccggaa cgccacccgc
    20581 tccagcgccg acggcagccg gggcgcgaac gtcagctcgc cgccgtggtc ccgcatgccg
    20641 cccagaccgg ccacgatcgc ctgccacgca cccgccagcg acgccatgtg caggccgttg
    20701 gccacgttgt ggtgcaagtc gttcaggtca gttagcgctg cctcggccag gtaggcgtaa
    20761 gcgaggtcca ggtgaccgca ctcagccgcg acgaccgact gagtccccgc cgacaacgac
    20821 gagtcgcgga cagtgcgagc ctcgtagtag gcgaagtcac gcgccttctg ttctagcgtg
    20881 aacgcgtccc cacgcaggtg cagggcaaga accaggtcgg cctgcttcac gacctgcctg
    20941 cggtagagct cgaagtacgg gtagtgcaag agcagcgggt acttctctgc ctcggtcccc
    21001 tcgaagtccc actcttcgtg cgcggtgaac ccctcggcct gctcgtgtac cccgagcatc
    21061 tcgtcgaagg ggatgcgcat ccggtccgcc gcgcgcgacc a
//
