LOCUS       NZ_JAMTCR010000006     20993 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Actinokineospora globicatena strain DSM 44256
            LV79DRAFT_scaffold00005.5, whole genome shotgun sequence.
ACCESSION   NZ_JAMTCR010000006
VERSION     NZ_JAMTCR010000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinokineospora globicatena
  ORGANISM  Actinokineospora globicatena
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Actinokineospora.
REFERENCE   1  (bases 1 to 820944)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 820944)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUN-2022) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: AllPaths v. r46652
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 261.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024171945.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 06:43:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,731
            CDSs (total)                      :: 6,666
            Genes (coding)                    :: 6,609
            CDSs (with protein)               :: 6,609
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 8 of 57
            Pseudo Genes (incomplete)         :: 49 of 57
            Pseudo Genes (internal stop)      :: 2 of 57
            Pseudo Genes (multiple problems)  :: 1 of 57
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:43:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 377894
            Orig. end                         :: 398887
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAMTCR010000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20993
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="furan"
                     /region_number="3"
                     /rules="(mmyO or AvrD)"
                     /tool="antismash"
     cand_cluster    1..20993
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(mmyO or AvrD)"
                     /kind="single"
                     /product="furan"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20993
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10993](+)"
                     /cutoff="20000"
                     /detection_rule="(mmyO or AvrD)"
                     /neighbourhood="10000"
                     /product="furan"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10993
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(mmyO or AvrD)"
                     /neighbourhood="10000"
                     /product="furan"
                     /protocluster_number="1"
     misc_feature    complement(282..300)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.29"
                     /tool="antismash"
     gene            1030..1473
                     /locus_tag="LV79_RS29190"
                     /old_locus_tag="LV79_005754"
     CDS             1030..1473
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS29190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_005754"
                     /product="hypothetical protein"
                     /protein_id="WP_253841499.1"
                     /transl_table=11
                     /translation="MGRNAGFDEFVLVTARAVVADLAPDEAVVVDVVGQEFLRDPERLL
                     SRDGSRPPVLGSGIGTVVTMVTPVALAVGASVYQHLLGKAGESLANGTVKLVRKVFRRD
                     EGAADEVRRVVVERARELGRSADEANRIADTVIAELTRDDDAA"
     gene            1454..4495
                     /locus_tag="LV79_RS29195"
                     /old_locus_tag="LV79_005755"
     CDS             1454..4495
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013594.5"
                     /locus_tag="LV79_RS29195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005755"
                     /product="M48 family metalloprotease"
                     /protein_id="WP_253841500.1"
                     /transl_table=11
                     /translation="MTTTPPEARVAGAGVPAGTTFRFLTLVGIAVAITAYVADHFASLT
                     GADRGLARLRCQVVSGVYPDASVRIEPDEGKWNSYYDCLYALRGTQLLWLGGALALLAL
                     VTWLFYVAQPAWRIRRGRLVLLRDVPALWARLEPTLTELTRKAGLAALPEFRLDPGSTR
                     AGGVAFGTHRRSVVCLDVGLVLLHDRDRPAFDAVVLHELAHLRHRDVPITYATIAVWRA
                     VLLVAVLPFTVSLVRSQVVTPDVDLLALLVWSPLLVLLAYAARASVLRVREHHADVLVV
                     AWTGADDPFRTLPDVRSPRFTTHPSRAARLAVTQDPRLLLRPGFWAFFLGGLTWQVVAN
                     TAGMALGTLWLRSDSAGPAVLRLAWSAGAAALVGVAAWRGAEYVRLGGDRRRVFLAPGL
                     GIGLGLGLGGLVVPMVVLDPLGVQFAPLTLWLRAVAVVVAVLVCAWAGWCVSLARSRFQ
                     RVAVAVAVVVVCWSVLGWLPTAYGYSGLWDSMLAPALERLGDIAGGGVDAVLLGAAALP
                     LFADVDRVLTTVALGLVWLVPALLGRPPRAAFTVGAAGMAVAAIAVLVIGGADPLVATA
                     WQLAAVAVVQLAVAWVARRSGVVAAVVAAWLTGIAGCLAIWAAHWSAGEVDAVLARQPM
                     RVLPFTALVAAALVAVVGRRRVAARPVRRVALIPVVALTAAVLVPFPVATSSAVALLPR
                     QPTTGIVDPRRALFIWAHGGGMALLSDVGQAQSRALLGMAEDDRAAQVARCEELLDRIR
                     VAREYPDPPEPVARGHWNSGMDASRLGAQECVRIFSGPDGDPNPVSTAFTAAADDFLPL
                     LRAISDVATSVPPEPPAPTTSTPPPPPPPPPAPPVDLATMLLTAADLPRGAKEKPPSTG
                     GSSSDIRTEPSDCGVDVGPPELTKASRTFDMPDGSWISTSVYRYTDDGGEAMRRIAENY
                     AHCHQYRVFSGNIKQKVTIDIVGGTPWVADITYDGGFVVFRSRQVWIVKGELLAYVGVS
                     GKRKPDPSLVDSLAATLASRLVTR"
     misc_feature    4028..4030
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4485..5261)
                     /locus_tag="LV79_RS29200"
                     /old_locus_tag="LV79_005756"
     CDS             complement(4485..5261)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (2-174). E-value: 9e-11. Score:
                     33.9. Matches aSDomain:
                     nrpspksdomains_LV79_RS29200_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681605.1"
                     /locus_tag="LV79_RS29200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005756"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_253841501.1"
                     /transl_table=11
                     /translation="MSTALVTGASAGLGVEFAEQFAARGYDVVLVARSEHRLQELAKRL
                     NSTYGVRAEVIAQDLSAVDAAPAITRELAARGVTVHTLVNNAGFGSAGRFEEIADGRDR
                     EQLMVNVVSLVGLTRALIPQVLDGKGAVINVASTAGLQPTPYFATYGAGKAFVLTFSLA
                     LRAELKGRATVLCVCPGPTETQFFDTVEVGRKAAIGGKFMTARAVVAATLRALDRDRGY
                     LVPGLLNSANAHLTPRRPRKMVAAIAERVSRGVLSG"
     aSDomain        complement(4740..5255)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LV79_RS29200_PKS_KR.1"
                     /evalue="9.00E-11"
                     /label="LV79_RS29200_PKS_KR.1"
                     /locus_tag="LV79_RS29200"
                     /protein_end="174"
                     /protein_start="2"
                     /score="33.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGASAGLGVEFAEQFAARGYDVVLVARSEHRLQELAKRLNS
                     TYGVRAEVIAQDLSAVDAAPAITRELAARGVTVHTLVNNAGFGSAGRFEEIADGRDREQ
                     LMVNVVSLVGLTRALIPQVLDGKGAVINVASTAGLQPTPYFATYGAGKAFVLTFSLALR
                     AELKGRATV"
     CDS_motif       complement(5163..5249)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LV79_RS29200_0001"
                     /evalue="5.60E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="LV79_RS29200"
                     /protein_end="33"
                     /protein_start="4"
                     /score="12.6"
                     /tool="antismash"
                     /translation="LVTGASAGLGVEFAEQFAARGYDVVLVAR"
     gene            5354..5923
                     /locus_tag="LV79_RS34195"
                     /old_locus_tag="LV79_005757"
     CDS             5354..5923
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681604.1"
                     /locus_tag="LV79_RS34195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005757"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_285470291.1"
                     /transl_table=11
                     /translation="MVTQGRPLRADAERSVRAILEAAEKVLAANPAASLEQVAEAAGVA
                     RTTVHRRFANRQALVDTLVTTVMDQLDAVIDAANPDTAPPLVALHQVTASVLRLKLGWP
                     FAMTESFAPDSRWSERQHHTATRCVTLLARAQTTGHIAPDADLDWTCKVYYALIGEAAH
                     NTTEPDPDLLATKVITTLLHGAGPRS"
     gene            5966..6121
                     /locus_tag="LV79_RS29210"
                     /old_locus_tag="LV79_005758"
     CDS             5966..6121
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS29210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_005758"
                     /product="hypothetical protein"
                     /protein_id="WP_253841502.1"
                     /transl_table=11
                     /translation="MAESAREKHYKVAFDLPDDVAAYALASVERLWVSRTATRFHVEVH
                     NTPFLA"
     gene            complement(6493..7374)
                     /locus_tag="LV79_RS29215"
                     /old_locus_tag="LV79_005759"
     CDS             complement(6493..7374)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037627.5"
                     /locus_tag="LV79_RS29215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005759"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_253841503.1"
                     /transl_table=11
                     /translation="MGKSGGTSRRREELGHFLTTRRARLSPADFGLSVSSGRRRTPGLR
                     REEVAVLAGIGTSWYTWLEQGRDINVSEPVARAVGHALRLNRSELCYLYQLLGISPPPA
                     KATVGECPNLDLRQVVDECLPSPALVVDSLWNLVASNRSARLVFGLTDRDRNLLTSFFC
                     REEIWSRYTNPDRMARMAVAQFRVSAAGHYDDPIFNNLIRTLCAQSEKFTQLWHTHEVL
                     DARLSSKEVDHPEVGRLSFDTQSWLLDGPDRIRMFLHVPHRMSDTRAKLATLLAAEPHH
                     PEVTAVAGRATA"
     misc_feature    complement(7300..7302)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7492..7505
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.42"
                     /tool="antismash"
     gene            complement(7643..8884)
                     /locus_tag="LV79_RS29220"
                     /old_locus_tag="LV79_005760"
     CDS             complement(7643..8884)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.5"
                     /locus_tag="LV79_RS29220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005760"
                     /product="MFS transporter"
                     /protein_id="WP_253841504.1"
                     /transl_table=11
                     /translation="MPGEVPAGRVPVAGRARLTPGGGMSAGLVRLFAVAAGLAVANVYY
                     AQPLLTAIAAEFGVGSATASALVTVTTAGYAVGLGLVVPLADILDRRRLVVAMLSAVAL
                     IQAAASAAPSITVLMLVSAVLAPCAVVAPIMVAFAATLAAPQRRGQVTGTVMSGVLVGV
                     LLARTGGGLVAEWAGTWRAVYAAAAVLMALLAAVLWRVLPDVRVADRLGYGALLRSVVA
                     IVREEPVLRLRCAYGFLSFAGFSAFWATTAFLLAGEPYHYGAGVIGAFGLLGAVGAYAA
                     RATGRFVDRGRGELVTGSLLGLVLLSWGLMALGGGRWIVPLVLGVVALDLGVQGVQVAN
                     LSAVYQLRPEARSRITMAYTGTYFLGGAVGAAASGAAYAAAGWLAVCGVGALLAAACLL
                     LWAVRGAAVRPPPG"
     gene            complement(9058..9483)
                     /locus_tag="LV79_RS29225"
                     /old_locus_tag="LV79_005761"
     CDS             complement(9058..9483)
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1144: thioesterase superfamily protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004559050.1"
                     /locus_tag="LV79_RS29225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005761"
                     /product="PaaI family thioesterase"
                     /protein_id="WP_253841879.1"
                     /transl_table=11
                     /translation="MEVDTVFGVPAHPGYQAEQLIAKLGIRLVECGPGRVVGTMPVTGN
                     RQPVGIMHGGANAAFAETLGSLAAWAHAGPGGRAVGLDLSCTHHRWVSSGLVTGTATAL
                     HEGRATATYEIVIVDESGRRTCTARLTCAIGKRRRTT"
     gene            10001..10993
                     /locus_tag="LV79_RS29230"
                     /old_locus_tag="LV79_005762"
     CDS             10001..10993
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) furan:
                     AvrD"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017469.5"
                     /locus_tag="LV79_RS29230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005762"
                     /product="AvrD family protein"
                     /protein_id="WP_253841505.1"
                     /sec_met_domain="AvrD (E-value: 1.9e-100, bitscore: 331.8,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNPAPPRPTVDDYLGDGAKRFFSAGYRRVGYHFGPVATDVASTS
                     DATVRTHVGLSYPTDWSKKSAGVDLRPHLSTIDAILFGATLAELAVVSAFGLDEQARRA
                     AWVRRVRIRAGQSPEEDLRRLPLSAQLTDTTTEPGGLSTVSTVDSQVGSMRVRCEVVHT
                     GGAVTPGATEHDSPDALLGPAADRYYGTGFARVHHHLDDLALDVPNTSAEAVVRLEPSD
                     ATAGIEGAYQPAPTMVEAFAAGLQLAQVLLYEMDGMRRSGSNTLWMRSTTLTATRPVAG
                     TGPFALRTSLATTNLVEMNGGVWRTADIHTELAGVRFTCAVAHALPRGI"
     gene            11023..11739
                     /locus_tag="LV79_RS29235"
                     /old_locus_tag="LV79_005763"
     CDS             11023..11739
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS29235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_005763"
                     /product="AAA family ATPase"
                     /protein_id="WP_253841506.1"
                     /transl_table=11
                     /translation="MKLAISGTYSSGKTLTSYALSHLVDMPRTRARTMRELLPFAVPGK
                     TLEQCDGAELIQLIVRRHVERVVHESHLSTGFVSDGSSLQEWLYGSVRVIVGINPNDSV
                     HLSDVQTVERTPEMLFFEHVMDQLGVAIKEHVKNTYDVFVHLPNELELAKDGHRPVNER
                     FRRLADEGIAAAIDELGIPRHVIGGTLVQRLEGIVEVLGLTPVTDVHTAIARAQDEYRK
                     VDMTIESDRAWAVASA"
     gene            11772..12773
                     /locus_tag="LV79_RS29240"
                     /old_locus_tag="LV79_005764"
     CDS             11772..12773
                     /EC_number="2.3.1.180"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019811556.1"
                     /locus_tag="LV79_RS29240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005764"
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="WP_253841507.1"
                     /sec_met_domain="fabH (E-value: 6.2e-113, bitscore: 372.5,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRAAVLAGVGSAVPDRVVTNDMYAARMDTTDEWIRTRTGIRERR
                     HLERGSATSDLAAEAGRRALKSAGVGAVDAVVLATTTPDHPCPATAPTVAAALGLGTVP
                     AYDVGAVCSGFLYALASGAGLIALGTAERVLVIGAEAFTTIIDQSDRGTAPIFGDGAGA
                     VVLSAGDQSQPGALLAFDLGSDGDLADLIIIPGGGSRQRASGLPAAPGDEYMAMHGREV
                     FRHAVLRMTESSRTVLARTGWDVGSLDWLVGHQANVRILRAVADHLGLAQERAFVNVDR
                     YGNTAAASIPLALDDAATTGLITPGDRIVLTAFGGGATWGAIALEWPNLAVA"
     misc_feature    12815..12835
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.07"
                     /tool="antismash"
     gene            12820..13065
                     /locus_tag="LV79_RS29245"
                     /old_locus_tag="LV79_005765"
     CDS             12820..13065
                     /GO_function="GO:0000035 - acyl binding [Evidence IEA]"
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (6-72). E-value: 2e-15.
                     Score: 48.8. Matches aSDomain:
                     nrpspksdomains_LV79_RS29245_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.5"
                     /locus_tag="LV79_RS29245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005765"
                     /product="acyl carrier protein"
                     /protein_id="WP_253841508.1"
                     /sec_met_domain="PP-binding (E-value: 5e-13, bitscore:
                     44.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTTINERVLALVADKAEVPPARLSLDSTLEDIGLDSLHLMEIAL
                     WAQKEYGVVIAEGELHHEQTLAEALALLDARTGATA"
     misc_feature    complement(12821..12835)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.34"
                     /tool="antismash"
     aSDomain        12838..13035
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LV79_RS29245_PP-binding.1"
                     /evalue="2.00E-15"
                     /label="LV79_RS29245_PP-binding.1"
                     /locus_tag="LV79_RS29245"
                     /protein_end="72"
                     /protein_start="6"
                     /score="48.8"
                     /tool="antismash"
                     /translation="ERVLALVADKAEVPPARLSLDSTLEDIGLDSLHLMEIALWAQKEY
                     GVVIAEGELHHEQTLAEALAL"
     gene            13062..13772
                     /locus_tag="LV79_RS29250"
                     /old_locus_tag="LV79_005766"
     CDS             13062..13772
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR01490.1"
                     /locus_tag="LV79_RS29250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005766"
                     /product="HAD family phosphatase"
                     /protein_id="WP_253841509.1"
                     /transl_table=11
                     /translation="MTHRRAAFFDVDGTLITITSIFRFLAFDTAERGLPDSVHTGHLAE
                     LARVKAAGANRETANRAFYRAFAGRPAADLAAAGERWFTAEYAKGGLFDPRVLTMLRAH
                     RAAGDHVVLLSGSFPPCLTPIARFACADVVLCTEPEVVAGELTGAVGTPMVGANKAMAV
                     REFAAARGIDLTDCFAYGDDHSDLPVLELAGCPVAVGDEPVLRAHAERAGWRRIPPLAG
                     EDSEQREEVPCPSR"
     gene            13757..14713
                     /locus_tag="LV79_RS29255"
                     /old_locus_tag="LV79_005767"
     CDS             13757..14713
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (23-312). E-value: 1.7e-43.
                     Score: 140.9. Matches aSDomain:
                     nrpspksdomains_LV79_RS29255_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801290.1"
                     /locus_tag="LV79_RS29255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005767"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_253841510.1"
                     /sec_met_domain="ADH_N (E-value: 2.6e-07, bitscore: 25.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.3e-12, bitscore:
                     41.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQMTVMQTVAAGGPEVLVPATVPRPVPLPTEVLVRVHAAGVNP
                     VDWKIRAGVFPPGGLGAHPFTQGWDVAGVVESGPRVTRFQPGDEVFGLLWFPRQAGGYG
                     EYVTAPARQFARKPASLSFAEAAALPMAGLTAWQTLVDVAGVGAGTRVLVTAAAGGVGH
                     LACQIAKHRGAVVTGTASAPKHEFLAGLGVDNAVDYTKVDVSTTVRDQDVVLDLLGGDH
                     TLGLLDTLRPGGLLVLTIGQVSPEVTRAAEARGVRVTPFLVEPDSTGLAAVADLVDREA
                     VRVHVEHILPLAEAGKAHEIGAANRTTGKIVLAVTGT"
     aSDomain        13826..14692
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LV79_RS29255_PKS_ER.1"
                     /evalue="1.70E-43"
                     /label="LV79_RS29255_PKS_ER.1"
                     /locus_tag="LV79_RS29255"
                     /protein_end="312"
                     /protein_start="23"
                     /score="140.9"
                     /tool="antismash"
                     /translation="VPRPVPLPTEVLVRVHAAGVNPVDWKIRAGVFPPGGLGAHPFTQG
                     WDVAGVVESGPRVTRFQPGDEVFGLLWFPRQAGGYGEYVTAPARQFARKPASLSFAEAA
                     ALPMAGLTAWQTLVDVAGVGAGTRVLVTAAAGGVGHLACQIAKHRGAVVTGTASAPKHE
                     FLAGLGVDNAVDYTKVDVSTTVRDQDVVLDLLGGDHTLGLLDTLRPGGLLVLTIGQVSP
                     EVTRAAEARGVRVTPFLVEPDSTGLAAVADLVDREAVRVHVEHILPLAEAGKAHEIGAA
                     NRTTGKIV"
     CDS_motif       14201..14263
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LV79_RS29255_0001"
                     /evalue="1.20E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="LV79_RS29255"
                     /protein_end="169"
                     /protein_start="148"
                     /score="14.8"
                     /tool="antismash"
                     /translation="GTRVLVTAAAGGVGHLACQIA"
     gene            14872..16404
                     /locus_tag="LV79_RS29260"
                     /old_locus_tag="LV79_005768"
     CDS             14872..16404
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020662507.1"
                     /locus_tag="LV79_RS29260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005768"
                     /product="MFS transporter"
                     /protein_id="WP_253841511.1"
                     /transl_table=11
                     /translation="MSATLPPVERRATATITLIAVCVACGLLPASLTGTSIALPDIGSD
                     LGADLVSVQWVVNAYNLAFASVMLAAGALADLLGRKRMFTIGLLAFLLCTAGVGAVSDI
                     VLVDLLRALAGVGAAMVLTSASALLAQAFDGPARLKAFGLLGSSFGLGLALGPSTSGML
                     VSLWGWRAVFFAHALIAAAVLLALPALRESRDPDATGVDWPGTTTFSGALVALTLALVE
                     GPQRGWGDALVLALFAGFVVLIVAFVAVERRQARPMFDLGLFRQPRFVAVCLMPVLLAF
                     GFVCLLVFLPSFFIGITGMGAKQAGLTMLLLTVPVLVFPVVAGTLAKTIPARVLLGVSL
                     LLVAVGAAWLTVIDRAAGAGTLIGPLLVIGTGVGISFGLLDGAAIGSVDPARAGMAAGM
                     FNTMRLTGEAVAIAGMGSLLVSLTRGGLGGLTDYPDAGAVGEVANKVAQGEIAAVAARV
                     GETHRAAFVDFVSGSYTSAFHTVLWILAAVCALGAPVIAVMLRDRPAVPVHA"
     gene            16429..17946
                     /locus_tag="LV79_RS29265"
                     /old_locus_tag="LV79_005769"
     CDS             16429..17946
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.5"
                     /locus_tag="LV79_RS29265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005769"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_253841512.1"
                     /transl_table=11
                     /translation="MSETSPVLVVGAGPVGLTAAAELARRGVPVRLVDRAAEPSPLTKA
                     LMVWPRTLEVFRLLGGSGHLDTYGLPVQAFRYYSESREVCALAFDAETKPSVVTQPDVE
                     ALLRKALADAGGVIEWETAVTAVRHDGTGVEAAIAAPDGTETVERFSYLIGADGASSLV
                     RKQIGLEFHGATYPNVFILADVSLDGDLQRDAVHYYCSSKGIMVLIPLYNGRFRVFTAG
                     PPGMKPEELTEQVLQDYVDLRGPGGLRTHDVSWKTTFSIHARHTERLRVGRVFLAGDSA
                     HVHSPAGGQGLNTGVTDAHNLAWKLALVHQGKADPVLLDTYEVERRSVAAAVVRQADVQ
                     TKAWMLKKKWQIRSRDVAAGLAEKLGLFDRYYSPWLAGLTNHYPENPAVTGPVAKRAGT
                     KRDRLLSGYLAPEPLRAVLPIDRYTLVVHGSTNTADQLAARHPDLVTVREISEAGVVDD
                     AEGTPVTIGWRPRRPMAALVRPDGYVAAVDKTPDLPALRAHLAALHG"
     gene            17977..18378
                     /locus_tag="LV79_RS29270"
                     /old_locus_tag="LV79_005770"
     CDS             17977..18378
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024092.5"
                     /locus_tag="LV79_RS29270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005770"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_253841513.1"
                     /transl_table=11
                     /translation="MSTRDTEATITEFFTRFGAGDRPGMLELFADGAELAVAGADTVPW
                     TGSRVEAAAIDEFLRIALEDVNTEVFDIDRIVVDGADGVVLGSLAHRITATDKVFASAF
                     ALHVRVVDGLITSYRMFEDSHAAAVSWAG"
     gene            18434..18664
                     /locus_tag="LV79_RS29275"
                     /old_locus_tag="LV79_005771"
     CDS             18434..18664
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023802.5"
                     /locus_tag="LV79_RS29275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005771"
                     /product="papain-like cysteine protease family protein"
                     /protein_id="WP_253841514.1"
                     /transl_table=11
                     /translation="MGGRRLAVVAGFATVISWSSGGAHAEVIYGYDATNGTISVGDPWA
                     SYNRYWTSSYNNYLYNNQFAWTDSVSGIRRA"
     misc_feature    18449..18451
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18671..19141
                     /locus_tag="LV79_RS29280"
                     /old_locus_tag="LV79_005772"
     CDS             18671..19141
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS29280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_005772"
                     /product="hypothetical protein"
                     /protein_id="WP_253841515.1"
                     /transl_table=11
                     /translation="MPRPTRFRLSTVALVVAALALSAPQAHADPVRRAEVVPLPRTALA
                     AAVAAATTPQAISIARTNFKQGGQPEPATITVAGSGLPVYTLAPDFVRGDPAAAPGRFA
                     YVAVVATADDGRQATMAAVALTAVTVAWRRTRSSVSTVRRRAQGADADGEQG"
     gene            complement(19138..20001)
                     /locus_tag="LV79_RS29285"
                     /old_locus_tag="LV79_005773"
     CDS             complement(19138..20001)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098423.1"
                     /locus_tag="LV79_RS29285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005773"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_253841516.1"
                     /transl_table=11
                     /translation="MDDRNELGRFLKSRRARVDPADVGIAVHARRRVAGLRREEVASLA
                     GISVEYYVRLEQGRASRPSESVLEALARALTLDDVERRYLDELVRPRPAATRGPRTERA
                     RPELAQLLSFLDRVPALVINHRLDVLAWNHLAGQLFFDFAAASPRQRNLARFGFLDPNS
                     QERFVDWQDVCRATAGTLRLAAGRHTHDEALATLLGELTMKSDLFRTLWAGRDVKQRTH
                     GTKRFRHPVVGELTLRFENFDLPGESDQRLVTFSPEPASPAEQALSLLAMWSTPPLHDA
                     VEEPTA"
     gene            20137..20883
                     /locus_tag="LV79_RS29290"
                     /old_locus_tag="LV79_005774"
     CDS             20137..20883
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013866.5"
                     /locus_tag="LV79_RS29290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_005774"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_253841517.1"
                     /transl_table=11
                     /translation="MCHSTDSRPPALDNPGEVAEEGLLELTSADGTAFSAFRSIPAEPN
                     GVNIVILPDIRGTHPYYQALANRFAQAGYTTAAIDYYGRTAGPGVRDDKFEWQPLLPQV
                     KPEEVAADVRAAATYLEQHNTGPVFTVGFCFGGGQSWRLSAGALGVTGVIGFYGLPRLV
                     NDVVDDISAPLLLLLAGEDVATSQEEFQEFAGKLDAAGKDYDLHVYEGAPHSFFDASYA
                     EWQEACDDAWERVVGFIQKHTAPVAV"
ORIGIN
        1 tgggcgatgc ggccggtgaa gtcggtgtgg ctggcgttga tgccggagtc catcacgtac
       61 acccgagcgc cctgaccggg gttggtcggg taggtgtagg cgctgttgag cggcaggtcc
      121 cgctggtcga cgcggtcatc gccccagttc ggcgggttgg tctgggtgtc aacggcggcg
      181 tacttggtga cctgctgcac gtaggacacg ttcgggtcct tggcgacctt ggccgcctcg
      241 tccgccgaca tcgacgcggc gtacccgttg agcacggcgt cgtaggtgtg ccggacctgg
      301 ccgccgtact ggcgggtcat cgacgcggcc gacgcgctga ccgcctgcgc gccctggccc
      361 tggttcttga acaccacgat gtagcgcccg gccaccgcgt ccgccgagct cgcgttcacg
      421 atcgacacct gctgggcctc ggacgccgac gcacctgggg acaggaagta cgcggcgatc
      481 cccgaagcgg cggccgcgac ggcgaccacc ttcagtgttg tttttctcat gagtagccga
      541 attcctcact tcgcagggtg gtggggtcgg caacgtaggg aacggccgga ccccgcgcaa
      601 accctacgag cacattcccg ctgtgaacaa gaactggcct tccacagtta aaacagttgg
      661 taaagcccca ggtcaaccgt cggttccgat tcacctacgg atcttcctac ctaggatttc
      721 ggcggccggt acctatcgct acgcaatggc ccacccagtc aatcgtcggc cgcctttctt
      781 gagtttcacc caaagccagc cgatttgcga caactcccgc cgggcgtcgt cccgtttccc
      841 tggaggcggt gttccggtcg cccgggtcga gaaatcgtcc gcgccggaat gggaccgcgc
      901 agtggaaccc gggcgtctcg aacggtgtac cgggtgtgcg ggaaccggtg gacgcgcgtc
      961 accgcttcgg tggaatgacc gggggtgggg gagtgcgcca cgatgctgtc ttctcggagg
     1021 gggagtcgag tggggcgcaa cgcggggttc gacgagttcg tgctggtgac ggcgcgggcg
     1081 gtggtggccg atctggcgcc tgacgaggcg gtcgtggtcg atgtcgtggg gcaggagttc
     1141 ctgcgcgacc ccgagcggct gctctcccgc gacggctcgc ggccgccggt gctcgggtcc
     1201 gggatcggca cggtcgtgac catggtgacg ccggtggccc tcgccgtggg tgcctcggtg
     1261 taccagcacc tgctgggcaa ggcgggggag tccctggcca acggcaccgt caagctggtc
     1321 cgcaaggtct tccgccgcga cgagggcgcc gccgacgagg tccgccgggt cgtcgtcgag
     1381 cgcgccaggg aactgggccg ctccgcggac gaggccaacc ggatcgccga caccgtgatc
     1441 gccgagctca cccgtgacga cgacgccgcc tgaggcgcgg gtggccgggg cgggtgtccc
     1501 ggcggggacg acgttccggt tcctgacgct ggtcgggatc gcggtggcga tcaccgctta
     1561 cgtggccgac cacttcgcgt cgctcacggg cgcggaccga ggtctggcca gactgcggtg
     1621 ccaggtggtc agcggcgtgt acccggacgc ctcggtgcgc atcgagcccg acgagggcaa
     1681 gtggaactcc tactacgact gcctctacgc cctgcgcggc acccagttgc tctggctcgg
     1741 cggcgccttg gcgttgctcg cgctggtgac ctggctgttc tacgtcgccc agcccgcctg
     1801 gcggatcagg cgcggacgcc tcgtgctgct gcgcgacgtc cccgcgctgt gggctcgcct
     1861 ggaaccgacc ctcaccgagc tcacccgcaa ggccgggctg gccgcgctgc ccgagttccg
     1921 gctcgacccg ggcagcaccc gcgcgggcgg ggtcgcgttc ggcacgcacc gccggtccgt
     1981 ggtctgcctc gacgtgggac tggtgctgct gcacgaccgc gaccggcccg cgttcgacgc
     2041 cgtcgtgctg cacgaactcg cccacctgcg ccaccgcgac gtgccgatca cctacgccac
     2101 catcgcggtc tggcgggccg tgctgctggt ggcggtcctg ccgttcaccg tcagcctggt
     2161 gcgctcgcaa gtcgtgacgc cggacgtgga cctgttggcg ctgctggtgt ggtccccgct
     2221 gctggtcctg ctcgcctacg cggcgcgggc ctcggtgctg cgggtccgcg agcaccacgc
     2281 cgacgtgctg gtggtcgcgt ggaccggcgc cgacgacccg ttccggaccc tgccggacgt
     2341 gcggtcgccc cgcttcacca cgcacccgag tcgcgcggcc cggctcgccg tcacccagga
     2401 cccgcgcctg ctcctgcggc ccgggttctg ggcgttcttc ctcggcgggc tcacgtggca
     2461 ggtggtcgcc aacaccgcgg gcatggcgct gggcaccctg tggctgcgct cggactcggc
     2521 cggaccggcc gtgctgcggc tggcgtggtc ggccggggcg gcggcgctgg tgggcgtcgc
     2581 ggcgtggcgg ggcgcggagt acgtgcgcct gggcggtgac cggcgtcggg tgttcctcgc
     2641 gcccgggctg gggatcggcc tcgggttggg gctgggcggg ctggtcgtgc cgatggtcgt
     2701 cctcgacccg ctgggggtgc agttcgcgcc gctgaccctc tggttgcgcg ccgtcgccgt
     2761 ggtcgtggcg gtgctggtgt gtgcgtgggc cgggtggtgc gtgtcgctgg ccaggtcgag
     2821 gttccagcgg gtcgcggtgg ccgtcgccgt ggtggtcgtc tgctggagcg tgctggggtg
     2881 gctgcccacc gcgtacgggt attccgggct gtgggactcg atgctcgccc cggcgctcga
     2941 acggctcggc gacatcgcgg gcggtggtgt ggacgcggtg ctgctcgggg ccgcggcact
     3001 cccgctcttc gcggacgtcg accgggtgct gacgacggtc gcgcttggac tggtgtggct
     3061 cgtgcccgcg ctcttgggcc gtccaccccg ggcagcgttc accgttggtg cggcggggat
     3121 ggcggtggcg gccatcgccg ttctggtgat cggcggcgcg gatccgctgg tggcgaccgc
     3181 gtggcagttg gccgctgtgg ccgtggttca gctggcggtc gcgtgggtgg cgcgtcggtc
     3241 cggggtcgtc gcggcggtgg tggcggcgtg gctgaccggg atagcgggct gcttggcgat
     3301 ctgggccgcg cactggtcgg cgggcgaggt cgacgccgtc ctggcgcggc agccgatgcg
     3361 ggtcctgccg ttcaccgcct tggtcgcggc tgccctggtg gcggtggtgg ggcggcggcg
     3421 ggtggccgcc cgcccggtgc gacgggtggc gttgatcccc gtcgtcgcgc tgaccgcggc
     3481 cgtgctggtg ccgttcccgg tggccacctc ttcggcggtg gctttgttgc cgcgacagcc
     3541 caccaccggg atcgtcgacc cgcggcgggc gttgttcatc tgggcgcacg gtgggggaat
     3601 ggcgctgctc agcgacgtcg gacaggcgca gtcgcgggcg ctgttgggga tggccgagga
     3661 cgaccgggcc gcgcaggtgg cgcggtgcga ggagctgctg gaccggatcc gggtggcccg
     3721 cgagtacccg gatccgccgg agccggtcgc gcgtgggcac tggaactccg ggatggacgc
     3781 gtcgcggctc ggtgcccagg agtgcgtgcg gatcttctcc gggcccgacg gcgaccccaa
     3841 tcccgtctcc accgccttca ccgccgccgc cgatgacttc ctgcccctgc tgcgggcgat
     3901 ctcggatgtg gcgacaagcg tcccacccga gccgcccgcg ccgaccacca gcacgccgcc
     3961 accgccgccc ccacccccgc ccgcgccccc ggtcgacctg gcgacgatgc tgctcaccgc
     4021 cgcggactta ccgcgtggtg ccaaggaaaa gccgccgtcg accggtgggt cctcttcgga
     4081 catccgcacc gaaccgtcgg actgcggggt ggacgtcggc ccgcctgaac tgaccaaggc
     4141 ctcgcgcacg ttcgacatgc ccgacgggtc gtggatctcc acctcggtct accgctacac
     4201 cgacgatggc ggggaggcga tgcgcaggat cgccgagaac tacgcgcact gccaccagta
     4261 ccgcgtgttc tccgggaaca tcaagcagaa ggtcaccatc gacatcgtcg gtggcacacc
     4321 gtgggtcgcg gacatcacct acgacggcgg tttcgtggtg ttccgctcgc gccaggtgtg
     4381 gatcgtcaag ggcgagttgc tcgcttatgt tggtgtctcg ggtaagcgca agcccgatcc
     4441 gtcgcttgtg gactccttgg cggcgacgct ggccagccgg ttggtcaccc gctgagcacc
     4501 ccgcgcgaca cccgctcggc gatggcggcg accatcttgc gcgggcggcg cggggtgagg
     4561 tgcgcgttgg cggagttgag gagtccgggc acgaggtaac cccggtcgcg gtccagcgcg
     4621 cgcagggtcg cggccacgac tgctcgcgcg gtcatgaact tgccgccgat cgcggccttg
     4681 cgcccaacct cgacggtgtc gaagaactgg gtctcggtgg ggccggggca tacacaaagg
     4741 acagtggcgc ggcctttgag ctcggcgcgc agggcgaggc tgaaggtgag cacgaacgct
     4801 ttgcccgcgc cgtaggtggc gaagtacggg gtcggctgca ggcccgcggt ggaggcgacg
     4861 ttgatgaccg cgcccttgcc gtcgaggacc tgcgggatca gggcgcgggt cagcccgacg
     4921 aggctgacga cgttgaccat cagctgctcg cggtcccggc cgtcggcgat ctcctcgaag
     4981 cggcccgccg agccgaagcc cgcgttgttg accagggtgt gcacggtgac gcccctggcc
     5041 gccagctcgc gggtgatcgc cggggcggcg tcgaccgcgc tcaggtcttg ggcgatgacc
     5101 tcggcccgca cgccgtaggt gctgttcagg cgcttggcga gctcctggag ccggtgctcg
     5161 ctgcgcgcca ccagcacgac gtcgtacccc cgcgcggcga actgctcggc gaactcgacc
     5221 cccaggcccg cggacgctcc agtgaccagt gcggtgctca tgctgctctc cctctgctcg
     5281 gctaactgca tcacagttgt agcagataat gggctaactg caacagtggt gtcgcagatg
     5341 ttaggctggc tcggtggtca cccagggacg cccgctgcgc gccgacgccg aacgcagcgt
     5401 ccgcgcgatc ctggaagcgg ccgagaaggt gctggcggcg aacccggccg cgtccctgga
     5461 gcaggtcgcg gaggccgcgg gcgtcgccag gaccaccgtc caccggcgct tcgccaaccg
     5521 ccaggccctc gtcgacaccc tggtcacgac cgtcatggac cagctcgacg cggtgatcga
     5581 cgccgccaac cccgacaccg cgcccccgct ggtcgccctg caccaggtca ccgccagcgt
     5641 cctgcgcctg aaactcggct ggcccttcgc catgaccgag tccttcgccc ccgactcccg
     5701 ctggtccgaa cgccaacacc acaccgccac ccgctgcgtg accctcctgg cccgcgccca
     5761 gaccaccggc cacatcgccc ccgacgccga cctcgactgg acctgcaagg tctactacgc
     5821 cctcatcggc gaagccgccc acaacaccac cgaacccgac cccgacctcc tcgccaccaa
     5881 ggtcatcacc accctcctgc acggcgcggg cccgaggtct tgatcttcag ccggtacgct
     5941 gcgcggcatc gacctggggg gtgcggtggc ggagtccgcg cgggagaagc actacaaggt
     6001 ggcgttcgac ctgcctgacg acgtggcggc ctacgcgctc gcgtccgtgg agcgcctgtg
     6061 ggtcagccgc acggccacgc gcttccacgt cgaggtccac aacacgccgt tcttggcgtg
     6121 agaacggccg tccggttggt tcctcatcgc gtcaacggct tgtgcaatgg gaactcggct
     6181 ggacggttcg ggtgagcggt ggtcttgcgg gccggggcca agaatggttc aaccacggcg
     6241 gccagaactg gatgcggtgt gccggtggcg aactggggaa tggaagtcgc cgtcgtgtgt
     6301 agtggctggt cgtggacttg tgcgatcggc tcaccggtgg tgcggctagc acgctgccgg
     6361 aactgggcag gagtgtttcg ctcagatttc cggcacatga gcgaaatcga ccgggaaagc
     6421 cctggaccgg acttccgcga tgtgttcggc gacgaacgcg cccgggcagg ggcgggccct
     6481 gcccgggcgt gctcaggcgg tggcgcggcc cgcgacggcg gtgacctcgg ggtggtgggg
     6541 ttcggcggcg aggagggtgg cgagtttggc cctggtgtcg gacatgcggt gcgggacgtg
     6601 caggaacatg cgtatccggt ccgggccgtc gagcagccag gactgggtgt cgaagctcag
     6661 cctgcccacc tcggggtggt cgacctcctt gctgctgagc cgggcgtcga gcacctcgtg
     6721 ggtgtgccag agctgggtga acttctcgct ctgcgcgcac agggtgcgga tgaggttgtt
     6781 gaagatcggg tcgtcgtagt ggcccgcggc gctgacccgg aactgggcga cggccatcct
     6841 ggccatccgg tcggggttgg tgtagcgcga ccagatctcc tcgcggcaga agaaactggt
     6901 cagcaggttg cggtcccggt cggtcaggcc gaacaccaac cgcgcggagc ggttgctggc
     6961 caccaggttc cacaggctgt cgaccaccag cgccgggctc ggcaggcact cgtcgacgac
     7021 ctggcgcagg tcgaggttcg ggcactcgcc gacggtcgcc ttcgccgggg gcgggctgat
     7081 ccccagcagc tggtagaggt agcacaactc ggaccggttg agccgcagcg cgtgccccac
     7141 cgcacgcgcg accggctcgg agacgttgat gtcgcgaccc tgctcgagcc acgtgtacca
     7201 ggaggtgccg atgcccgcga gcaccgccac ctcctcgcgg cgcaaaccag gcgttcggcg
     7261 tctaccggag gatacggaca aaccgaaatc ggccggggat aatcgagccc tgcgcgtcgt
     7321 caggaaatga cccaactcct cgcgccgcct actggtcccc ccactctttc ccatgttcgg
     7381 agttttgcca ctttcccact cgggtgtcaa gcggtaccgc acgaggtgat catgcgatta
     7441 ccggccgtgc aactcacgcg ctgccaccgg cggatcgttg agcggccaac gatttcgaaa
     7501 agcaaagaaa ctcgtcggta gctctgattc tggcgagaaa acgaaagcgt gcgcgtggcg
     7561 tggcgagttg ccccaggcgg cgatgtgcgc aattgctggg gaacgaacgc cgaaaccggt
     7621 tcgtgatcgg cgggtgcgcc ggtcaaccgg gcggcggccg gacggcggcg ccgcgcaccg
     7681 cccacagcag caggcaggcc gccgcgagca gggcgccgac cccgcacacc gcgagccagc
     7741 ccgccgcggc gtaggcggca ccggaggcgg ccgcgccgac cgcgccaccg aggaagtagg
     7801 tgccggtgta ggccatggtg atccggctgc gcgcctcggg ccgcagctgg tagaccgccg
     7861 acaggttcgc cacctgcacg ccctgcaccc cgaggtcgag cgcgaccacg ccgagcacca
     7921 gcggcacgat ccagcgcccg ccgcccagcg ccatcaaccc ccacgagagc agcaccaagc
     7981 ccagcagcga cccggtcacc agctccccgc gaccgcggtc gacgaaccgc ccggtggccc
     8041 gcgccgcgta cgcgcccacc gctcccagga gcccgaacgc gccgatgacg cccgcgccgt
     8101 agtggtaggg ctccccggcg agcaggaacg cggtggtcgc ccagaacgcg ctgaacccgg
     8161 cgaaggacag gaacccgtag gcgcagcgca gccgcagcac cggttcctcg cgcacgatcg
     8221 ccaccaccga gcgcagcagc gccccgtagc cgagccgatc ggcgacccgc acgtccggca
     8281 gcacccgcca cagcaccgcc gcgagcagcg ccatcagcac cgcggcggcc gcgtagaccg
     8341 cccgccacgt cccggcccac tcggccacca ggccaccgcc ggtgcgggcg agcagcaccc
     8401 cgaccagcac cccgctcatg accgtcccgg tgacctggcc gcgccgctgg ggtgccgcga
     8461 gcgtcgcggc gaaggcgacc atgatgggtg cgaccaccgc gcacggcgcc agcacggccg
     8521 agaccagcat cagcacggtg atcgacggcg ctgccgacgc ggcggcctgg atgagcgcca
     8581 ccgccgagag catcgccacc accaagcgcc tgcggtcgag gatgtccgcg agcggcacga
     8641 ccaggccgag gccgaccgcg tagcccgccg tcgtgaccgt gaccagcgcc gacgccgtcg
     8701 cgctgccgac cccgaactcg gcggcgatgg cggtcagcag cggctgggcg tagtagacgt
     8761 tggccaccgc gagccccgcc gcgacggcga agagccggac caggcccgcg gacatcccac
     8821 cgccgggcgt caaccgcgcc cgaccggcca ccggcactcg accggcgggc acttctccag
     8881 gcacatcgct ccagcaggta ggtccccgaa cgccgcgggc ggcggcgtgg tcaccctcga
     8941 tcgtcgcgca ccggcccggt cgcggccagg ctgtgccgga ccctcccccc ggtggtactg
     9001 gtactggcag ggccacccag cgctgagtcc actgtggatg agcagctcat gggatgatca
     9061 tgttgtgcgc ctgcgcttcc cgatggcgca ggtgagccgc gcggtgcacg tgcgcctgcc
     9121 ggactcgtcg acgatcacga tctcgtaggt ggccgtcgcc ctgccctcgt gcagggcggt
     9181 cgcggtgccg gtgaccaggc cggacgagac ccagcggtgg tgcgtgcagg acaggtcgag
     9241 cccgacggcg cgaccccctg ggcccgcgtg cgcccaggcg gcgagggagc cgagcgtctc
     9301 ggcgaaggca gcgttggcgc cgccgtgcat gatgccgacc ggctgccggt tgccggtcac
     9361 cggcatcgtg cccaccaccc gccccggccc gcactccacg agccggatgc ccagcttggc
     9421 gatcagctgc tccgcttggt agccggggtg cgcgggcacc ccgaacacgg tgtcgacctc
     9481 cagcgccgcg gagtcctcgg acgcggcgga gcccgcgggt cgggtgggcg gggtggagtt
     9541 gatgtgcggg gtgggcgggg cggagtcgat gtgtggaacg gagccatcgg acacagtggt
     9601 caccggggac ctccagggcg tgcggaccga acaggacgaa aggggcgacc gggccacggt
     9661 ggacggacac acgcgacaca ccgcgcacac aacacggggc gccgcaaccg gttccggcgg
     9721 tttcgccgcc gaactgttgc ccgtggacac ccggaccacc aggctgggtc gaccggccgc
     9781 cgcgctgcca tcggttgtgg cacaggtcat cctggtgccc gtggtacccg gatggcggta
     9841 cccgtacaaa gcgacgcagg ttccgcgccc ggcgccggtg tagcgtcgat ctcgacagcg
     9901 gccgtgggtg ttccggttct gtccgcagca cttcgctcgc ctgccaagtt cccccagcca
     9961 cgcggaccac ctcggtggcc gcggacggga gtgcccagag atgaccaacc cagcgccgcc
    10021 gcgcccgacg gtcgacgact acctcggcga cggcgccaag cgcttcttct cggcgggcta
    10081 ccgccgagtc ggctaccact tcggaccggt cgccaccgac gtcgccagca caagcgacgc
    10141 cacggtgcgc acgcacgtgg gactgtccta cccgaccgac tggtcgaaga agtccgcggg
    10201 cgtcgacctg cgcccgcacc tgagcaccat cgacgccatc ctcttcggcg ccaccctcgc
    10261 cgaactggcc gtggtcagcg ctttcggcct ggacgagcaa gcgcgccgcg ccgcgtgggt
    10321 gcgccgggtg cgcatccggg ccgggcagag ccccgaggag gacctgcgcc ggttgccgct
    10381 ctccgcccag ctgaccgaca cgaccaccga accgggcggc ttgtccacgg tatctactgt
    10441 ggacagtcag gtcggatcca tgcgggtccg gtgcgaggtg gtgcacaccg gtggtgcggt
    10501 caccccgggc gccactgagc acgacagccc ggacgcactg ctcggacccg ccgccgaccg
    10561 ctactacggc accggtttcg cccgtgtcca ccaccacctg gacgacctcg cgctggacgt
    10621 ccccaacacc tcggccgagg ccgtcgtccg cctggagccg tccgacgcca ccgccgggat
    10681 cgagggcgcc taccagcccg cgccgaccat ggtggaggcc ttcgccgcgg gtttgcagct
    10741 cgcgcaggtc ctgctgtacg aaatggacgg tatgcgccgc agcggcagca acacgctgtg
    10801 gatgcgctcc accacgctca ccgccacgcg cccggtcgcg ggcaccggtc cgttcgccct
    10861 gcgcaccagc ctggccacca cgaacctcgt cgagatgaac ggcggcgtct ggcgcaccgc
    10921 ggacatccac accgaactgg ccggtgtccg cttcacctgc gccgtcgccc acgcgctgcc
    10981 gcgcggcatc tgaaccacac caccgagaac ccaggggaac ccatgaagct cgccatctcc
    11041 ggcacctact cctccggcaa gaccctcacc tcctacgcgc tctcgcacct ggtcgacatg
    11101 ccgcgcaccc gggcccgcac catgcgcgag ctgctgccct tcgccgtgcc cggcaagacc
    11161 ctggagcagt gcgacggcgc cgagctgatc cagctgatcg tccgccgcca cgtcgagcgc
    11221 gtcgtgcacg agagccacct gagcactggt ttcgtctccg acggctcgtc gctgcaggag
    11281 tggctctacg gctcggtccg ggtgatcgtc ggcatcaacc ccaacgactc cgtgcacctg
    11341 tcggacgtgc agaccgtcga gcgcactccc gagatgctgt tcttcgaaca cgtgatggac
    11401 cagctcgggg tggccatcaa ggagcacgtc aagaacacct acgacgtgtt cgtgcacctg
    11461 cccaacgagc tggagctggc caaggacggg caccgcccgg tcaacgagcg cttccgcagg
    11521 ctcgccgacg agggcatcgc cgcggccatc gacgagctgg gcatcccccg gcacgtcatc
    11581 ggcggcaccc tggtgcagcg gctggagggc atcgtcgagg tgctcggcct gaccccggtg
    11641 accgacgtgc acaccgcgat cgcccgcgcc caggacgagt accgaaaggt cgacatgacg
    11701 atcgagtccg accgcgcctg ggccgtggcg tcggcctgag cgggacgagc gggcggggga
    11761 ggggcgcagc gatgggacgc gccgcggtgt tggcgggtgt ggggtcggcg gtgccggacc
    11821 gggtcgtcac caacgacatg tacgccgcca ggatggacac caccgacgag tggatcagga
    11881 cgcggaccgg catccgcgag cgcaggcacc tcgagcgcgg ctcggcgacc agcgacctgg
    11941 ccgccgaggc gggcaggcgg gcgctgaagt cggcgggcgt cggcgcggtc gacgcggtcg
    12001 tgctggccac cacgaccccg gaccacccgt gcccggcgac cgcgccgacc gtggccgcgg
    12061 cgctgggcct gggcaccgtc ccggcctacg acgtcggcgc ggtgtgctcc gggttcctct
    12121 acgccctggc cagcggggcg ggcctgatcg cgctgggcac ggccgagcgg gtgctggtga
    12181 tcggcgccga ggcgttcacc acgatcatcg accagtccga ccggggcacc gcgccgatct
    12241 tcggtgacgg ggcgggcgcg gtggtgctca gcgcgggcga ccagtcgcaa cccggcgcgc
    12301 tgctggcctt cgacctgggc agcgacggcg acctggccga cctgatcatc atccccggcg
    12361 gcgggtcccg gcagcgcgcc tccgggctgc ccgccgcgcc gggcgacgag tacatggcga
    12421 tgcacggccg ggaggtgttc cggcacgcgg tgctgcggat gaccgagtcc tcccgcaccg
    12481 tgctggcccg caccggctgg gacgtcggct cgctcgactg gctggtcggg caccaggcca
    12541 acgtgcgcat cctgcgcgcg gtggccgacc acctggggct ggcccaggag cgggcgttcg
    12601 tcaacgtcga ccgctacggc aacaccgccg ccgcgtcgat cccgctcgcc ctcgacgacg
    12661 cggcgaccac cgggttgatc acgccgggcg accggatcgt gctcaccgcc ttcggtggcg
    12721 gcgccacctg gggcgcgatc gccctggagt ggccgaacct cgcggtggcc tgagcccggc
    12781 gcggtccaca tcagacaaca cgaagcaggg agatatctcg tgaacaccac gatcaacgag
    12841 cgcgtcctgg cactggtcgc ggacaaggcc gaggtgccgc ccgcgcggct gagcctggac
    12901 agcaccctgg aggacatcgg gctggactcg ctgcacctca tggagatcgc gctgtgggcg
    12961 cagaaggagt acggggtggt catcgccgag ggcgagctgc accacgagca gaccctggcc
    13021 gaggccctcg cgctgctcga cgcccgcacc ggcgccaccg cgtgacccac cggcgggccg
    13081 cgttcttcga cgtcgacggg acgctgatca cgatcaccag catcttccgg ttcctcgcct
    13141 tcgacaccgc cgagcgcggc ctgccggact ccgtccacac cggacacctg gccgagctgg
    13201 cgcgggtcaa ggcggcgggg gcgaaccggg agacggccaa ccgggcgttc taccgggcct
    13261 tcgccggtcg tcccgccgcc gacctggccg ccgccggaga gcggtggttc accgccgagt
    13321 acgccaaggg cgggctgttc gacccgcggg tgctgaccat gcttcgcgcg caccgggccg
    13381 caggcgacca cgtcgtgctg ctgtccgggt cgttcccgcc gtgcctgacc ccgatcgccc
    13441 ggttcgcctg cgcggacgtc gtgctgtgca ccgagccgga ggtcgtggcg ggcgagctca
    13501 ccggcgcggt cgggaccccg atggtcggcg cgaacaaggc catggccgtg cgcgagttcg
    13561 ccgccgcgcg ggggatcgac ctgaccgact gcttcgccta cggcgacgac cactccgacc
    13621 tgccggtgct cgaactggcc gggtgcccgg tggcggtcgg cgacgagccg gtgctgcgcg
    13681 cgcacgccga gcgggccggg tggcgccgca tccctcccct cgccggggag gactccgagc
    13741 aacgagagga agtcccatgt ccgagcagat gaccgtcatg cagacggtgg ccgccggtgg
    13801 tccggaggtg ctggtgcccg ccaccgtgcc gcgcccggtg ccgctgccca ccgaggtgct
    13861 ggtgcgggtg cacgcggccg gggtgaaccc ggtcgactgg aagatccgcg ccggggtctt
    13921 cccgcccggc gggttgggcg cgcacccgtt cacccagggc tgggacgtgg cgggcgtggt
    13981 cgagtccggc ccgcgcgtca cccgcttcca gcccggcgac gaggtgttcg gcctgctgtg
    14041 gttcccccgc caggcgggcg gctacggcga gtacgtgacc gcacccgccc ggcagttcgc
    14101 ccgcaaaccc gcgtcgctgt ccttcgccga ggccgccgcg ctgccgatgg ccgggctgac
    14161 cgcctggcag accctggtgg atgtcgcggg ggtcggggcg ggcacccgcg tcctggtcac
    14221 cgccgccgcc ggtggggtcg ggcacctggc ctgccagatc gccaagcacc ggggcgcggt
    14281 cgtcaccgga accgccagtg cgcccaagca cgagttcctc gcgggcctcg gggtcgacaa
    14341 cgccgtcgac tacaccaagg tcgacgtcag caccaccgtc cgcgaccaag acgtcgtcct
    14401 cgacctcctc ggcggcgacc acaccctcgg cctgctcgac accctccgcc cgggcggtct
    14461 cctggtgctc accatcggcc aggtcagccc ggaggtcacc cgcgccgccg aggcgcgcgg
    14521 cgtccgggtg accccgttcc tggtcgaacc ggactccacc ggcctggccg cggtggccga
    14581 cctcgtggac cgggaagccg tgcgggtgca cgtggaacac atcctgcccc tggcggaagc
    14641 gggcaaggcc cacgagatcg gcgcggccaa ccgcaccacc ggcaagatcg tcctcgccgt
    14701 caccggcacc tgacccggtg tgagtccact gtggtcaccg tgggcgccgc ccactccatg
    14761 agtcgggtgc gataggccca tcgagcgggt gtcgtgggtg tgcgcgggca ccgcgtcgcc
    14821 tcgttgatcg tgttcgccgt gatcccctct gtcgcaagga gttctgctgt cgtgtccgcc
    14881 accctccccc cggtcgagcg ccgtgccacg gcgacgatca ccctgatcgc ggtctgcgtc
    14941 gcgtgcgggt tgctgcccgc gtcgctgacc gggacgtcga tcgcgttgcc cgacatcggg
    15001 tccgacctcg gtgctgacct ggtcagcgtg cagtgggtcg tcaacgccta caacctcgcg
    15061 ttcgcgtcgg tgatgctcgc cgccggggcg ttggccgacc tgctgggccg caagcggatg
    15121 ttcaccatcg ggctgctggc cttcctgctg tgcaccgcgg gcgtcggcgc ggtgtccgac
    15181 atcgtgctgg tcgacctgtt gcgcgccttg gccggtgtcg gcgcggccat ggtgctgacg
    15241 tcggcgtcgg cgttgctggc gcaggctttc gacggtccgg cccggctcaa ggcgttcggg
    15301 ttgctcgggt cgtcgttcgg cctggggctg gcgctcgggc cgtcgacgtc cgggatgctg
    15361 gtgtcgctgt gggggtggcg cgcggtgttc ttcgcgcacg ccctcatcgc cgcggccgtc
    15421 ctgttggcac tgcccgcgtt gcgcgagtcg cgtgacccgg acgccaccgg tgtcgactgg
    15481 ccgggcacca cgaccttcag cggcgccttg gtcgcgttga ccctggccct tgtcgaaggc
    15541 ccgcagcgcg gctggggcga cgcgctggtc ctcgcgctgt tcgccgggtt cgtcgtgctg
    15601 atcgtcgcgt tcgtggcggt cgagcgcagg caggctcggc cgatgttcga tctggggctg
    15661 ttccggcagc ccaggttcgt cgcggtgtgc ctgatgccgg tgctgctggc cttcgggttc
    15721 gtctgcctgc tggtgttcct gccgtcgttc ttcatcggca tcaccggcat gggtgccaag
    15781 caggcgggcc tgaccatgct cctgctgacc gtgccggtgc tggtgttccc ggtcgtcgcg
    15841 ggcacgctcg ccaagaccat cccggccagg gtgctgctgg gggtgagcct gctgctggtg
    15901 gccgtgggcg ccgcctggct gaccgtgatc gaccgggccg cgggcgcggg cacgctgatc
    15961 gggccgctgc tggtgatcgg caccggcgtc ggcatctcct tcggcctgct cgacggcgcc
    16021 gcgatcggca gcgtcgaccc ggcgcgcgcg ggcatggcgg cgggcatgtt caacaccatg
    16081 cggctcaccg gtgaggccgt tgccatcgcg ggcatgggct cgctgctggt gagcctcacc
    16141 cggggcggtc tcggcggcct gaccgactac cccgacgcgg gcgcggtcgg cgaggtggcc
    16201 aacaaggtcg cccagggcga gatcgcggcg gtcgcagccc gggtggggga gacccaccgc
    16261 gccgcgttcg tcgacttcgt ctccggctcc tacaccagcg cgttccacac cgtgctgtgg
    16321 atcctcgccg cggtctgcgc actgggcgcg ccggtgatcg cggtgatgtt gcgcgaccgc
    16381 cccgctgtgc ccgtccacgc ctgatcccct tcactggagg cgaaacccat gtcagagaca
    16441 tccccggtcc tggtggtcgg cgcgggcccg gtcgggctca ccgccgccgc cgaactcgcc
    16501 cgccgcggcg tgccggtgcg gctggtcgac cgggccgccg aaccgagccc gttgaccaag
    16561 gcgctgatgg tctggccacg caccctggag gtgttccggc tgctcggcgg gtccgggcac
    16621 ctggacacct acgggctgcc ggtccaggcc ttccgctact actccgagag ccgcgaggtc
    16681 tgcgcgctcg ccttcgacgc cgagaccaag ccctcggtgg tgacccagcc ggacgtggag
    16741 gcgttgctgc gcaaggcact cgccgacgcg ggcggggtga tcgagtggga gaccgcggtg
    16801 accgccgtgc gccacgacgg caccggggtc gaggccgcca tcgccgctcc ggacggcacc
    16861 gagaccgtcg agcggttctc ctacctcatc ggcgcggacg gcgcgagcag cctggtgcgc
    16921 aagcagatcg ggctggagtt ccacggcgcc acgtacccca acgtgttcat cctcgccgac
    16981 gtcagcctgg acggcgacct gcagcgcgac gcggtgcact actactgctc cagcaagggc
    17041 atcatggtgc tcatcccgct ctacaacggg cggttccggg tgttcaccgc cggaccgccg
    17101 gggatgaagc cggaggagct gaccgagcag gtcctccagg actacgtcga cctgcgcggc
    17161 cccggtggtc tgcgcaccca cgacgtgtcc tggaagacga ccttcagcat ccacgccagg
    17221 cacaccgagc ggctgcgcgt cggccgggtg ttcctcgcgg gcgactccgc gcacgtccac
    17281 agcccggcgg gcggtcaggg cctcaacacc ggggtcaccg acgcgcacaa cctggcgtgg
    17341 aagctcgccc tggtccacca gggcaaggcc gacccggtgc tgctcgacac ctacgaggtc
    17401 gaacgccggt cggtggccgc cgccgtggtg cgccaggccg acgtgcagac caaggcgtgg
    17461 atgttgaaga agaagtggca gatccggtcc cgggacgtgg ccgccgggct ggccgagaag
    17521 ctgggcctgt tcgaccggta ctactcgccg tggctggccg ggttgaccaa ccactacccg
    17581 gagaacccgg cggtgaccgg accggtggcc aagcgggcgg gcaccaagcg cgaccggctg
    17641 ctcagcgggt acctggcacc ggagccgctg cgggccgtgc tgccgatcga ccgctacacc
    17701 ctggtggtgc acggttccac gaacaccgcc gaccagctcg ccgcccgcca tcccgacctg
    17761 gtcaccgtgc gcgagatcag cgaggcgggc gtggtcgacg acgccgaggg cacgccggtg
    17821 accatcggtt ggcgcccacg tcgtccgatg gccgccctcg tgcgcccgga cgggtatgtc
    17881 gccgccgtgg acaagacacc ggacctgccc gccctgcgcg cgcacctcgc tgcgctccac
    17941 ggctgagttt accgttaccc gttaaggaga atcgcattgt ccactcgcga caccgaagcc
    18001 acgatcaccg agttcttcac ccgcttcggc gccggtgacc ggcccggcat gttggaactg
    18061 ttcgccgacg gcgccgaact cgccgtcgcg ggcgccgaca ccgtgccgtg gaccggcagc
    18121 cgcgtcgagg ccgccgccat cgacgagttc ctccgcatcg ccctggagga cgtcaacacc
    18181 gaggtcttcg acatcgaccg gatcgtggtg gacggcgccg acggggtcgt gctcggctcg
    18241 ttggcgcacc ggatcaccgc gaccgacaag gtgttcgcca gcgcgttcgc cctgcacgtg
    18301 cgggtggtcg acgggcttat caccagttac cggatgttcg aggacagcca cgccgcggcg
    18361 gtctcctggg ccgggtgaaa tcggcgataa cggtcacccg ctgccctttg tgggcgcggg
    18421 tgaccgtttc gctgtgggcg gtcggcggtt agccgtcgtg gccgggttcg ccacggtgat
    18481 ctcgtggtcc tccggcggcg cgcacgccga ggtgatctac ggctacgacg cgaccaacgg
    18541 caccatcagc gtcggcgacc cgtgggccag ctacaaccgg tactggacct cgtcgtacaa
    18601 caactacctg tacaacaacc agttcgcctg gaccgactcg gtctccggga tccggagggc
    18661 ctgaccgccg atgccccggc ccacccggtt ccgactgtcc actgtggccc tcgtcgtcgc
    18721 cgcgctcgcc ctgtcggctc cgcaggccca cgcggacccg gtgcgccgcg ccgaagtggt
    18781 cccgctaccg cgcacggccc tcgccgccgc ggtagccgcg gccaccacgc cgcaggcgat
    18841 cagcatcgcc aggaccaact tcaagcaggg cggtcagccg gagcccgcga cgatcaccgt
    18901 cgcgggctcc ggcctcccgg tctacaccct cgcccccgac ttcgtccgcg gcgacccagc
    18961 cgccgccccc ggccgcttcg cctacgtcgc cgtggtcgcc accgccgacg acggccgcca
    19021 agccaccatg gccgcagtcg ccctcactgc cgtaaccgtg gcctggcgcc gcacccgctc
    19081 atcggtcagc acagtgcggc gccgtgccca gggcgccgat gccgatggcg aacagggcta
    19141 ggcggttggt tcctctacgg cgtcgtggag gggtggggtg ctccacatgg ccaggaggga
    19201 gagggcctgc tcggcgggac tggcgggttc gggggagaag gtcaccagcc gttggtcgga
    19261 ttcgccgggg aggtcgaagt tctcgaagcg gagggtgagt tcgccgacga ccgggtggcg
    19321 gaagcgcttg gtgccgtggg tgcgctgctt gacgtcccgg cccgcccaca gggtgcggaa
    19381 caggtcgctc ttcatggtca gttcgccgag cagggtggcc agggcctcgt cgtgggtgtg
    19441 gcggcccgcg gccaagcgga gggtgcccgc ggtggcccgg cagacgtcct gccagtcgac
    19501 gaagcgctcc tggctgttcg ggtcgaggaa gccgaagcgg gccaggttgc gctggcgggg
    19561 ggacgcggcg gcgaagtcga agaacagctg cccggcgagg tggttccagg cgagcacgtc
    19621 cagccggtgg ttgatcacca gggcgggcac ccggtccagg aacgacagca gctgcgccag
    19681 ctccggccgg gcccgctcgg tccgcggacc ccgggtcgcc gccgggcggg gccggaccag
    19741 ctcgtcgagg tagcggcgct ccacgtcgtc gagggtcagc gcgcgggcca gcgcctccag
    19801 caccgactcc gacggcctgc tggcgcgccc ctgctccagc cgcacgtagt actcgacgct
    19861 gatccccgcc agggacgcga cctcctcgcg ccgcagcccc gcgacccggc gcctggcgtg
    19921 cacggcgatg ccgacgtcgg ccgggtccac tcgggcgcgc cgggacttga ggaaccggcc
    19981 gagctcgttg cgatcgtcca cgccccgagt gtgcccgaga ccgccggtgc gcagcgtggt
    20041 cctgtcggta ccagtaacac caggggcctg gttgccaccc tcagcggcgg tcactgtggg
    20101 cccggtcagc tcctgaccac ctgaaaggtt cgcgcgatgt gccacagcac cgacagcagg
    20161 ccccccgctc tcgacaaccc cggtgaggtc gccgaggagg gtctgctcga gctgacctcc
    20221 gcggacggca ccgcgttctc ggcgttccgg tcgatcccgg ccgagcccaa cggggtcaac
    20281 atcgtgatcc tgcccgacat ccgcggcacc cacccgtact accaggcgct ggccaaccgg
    20341 ttcgcgcagg cgggctacac caccgcggcg atcgactact acggccgcac cgcgggcccg
    20401 ggcgtgcgcg acgacaagtt cgagtggcag ccgctgctcc cgcaggtcaa gcccgaggag
    20461 gtcgccgccg acgtgcgcgc cgcggccacc tacctcgagc agcacaacac cggtccggtc
    20521 ttcaccgtcg ggttctgctt cggcggcggc cagtcgtggc gcctgtccgc cggtgccctc
    20581 ggcgtcaccg gcgtgatcgg cttctacggc ctgcccaggc tggtcaacga cgtcgtcgac
    20641 gacatctccg cgccgctgct gctcctgctc gcgggcgagg acgtggcgac ctcgcaggag
    20701 gagttccagg agttcgcggg caagctcgac gccgcgggca aggactacga cctgcacgtc
    20761 tacgagggcg cgccgcactc cttcttcgac gccagctacg cggagtggca ggaggcctgc
    20821 gacgacgcgt gggagcgcgt ggtcgggttc atccagaagc acaccgcgcc cgtcgcggtc
    20881 tgatgccgac cgagcgcttc cgccgcggcg ccgcccggct ggccgagatg ggcggcgaca
    20941 tcgacgccat cgtcgccccg ctcgccgacg tcgccccgga cctggcccgg ttg
//
