LOCUS       NZ_JAMTCR010000003     22014 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Actinokineospora globicatena strain DSM 44256
            LV79DRAFT_scaffold00002.2, whole genome shotgun sequence.
ACCESSION   NZ_JAMTCR010000003
VERSION     NZ_JAMTCR010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinokineospora globicatena
  ORGANISM  Actinokineospora globicatena
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Actinokineospora.
REFERENCE   1  (bases 1 to 1257332)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1257332)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUN-2022) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: AllPaths v. r46652
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 261.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024171945.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 06:43:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,731
            CDSs (total)                      :: 6,666
            Genes (coding)                    :: 6,609
            CDSs (with protein)               :: 6,609
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 8 of 57
            Pseudo Genes (incomplete)         :: 49 of 57
            Pseudo Genes (internal stop)      :: 2 of 57
            Pseudo Genes (multiple problems)  :: 1 of 57
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:43:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 827907
            Orig. end                         :: 849921
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAMTCR010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22014
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="8"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22014
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22014
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12014](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12014)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     gene            complement(273..623)
                     /locus_tag="LV79_RS17080"
                     /old_locus_tag="LV79_003369"
     CDS             complement(273..623)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016331182.1"
                     /locus_tag="LV79_RS17080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003369"
                     /product="hypothetical protein"
                     /protein_id="WP_253837879.1"
                     /transl_table=11
                     /translation="MAQNPTTVLWRPTGPEELDLVRQADWRAWPPRRPDQPIFYPVLNE
                     DYAIKIARDWNVPHHGVGYVTRFHVDTDYLQRYPVQQAGGRTILELWVPAADLAEFNTH
                     LVGPIELVHEFR"
     gene            complement(689..1231)
                     /locus_tag="LV79_RS17085"
                     /old_locus_tag="LV79_003370"
     CDS             complement(689..1231)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680407.1"
                     /locus_tag="LV79_RS17085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003370"
                     /product="hypothetical protein"
                     /protein_id="WP_253837882.1"
                     /transl_table=11
                     /translation="MLSSPVWRGSPAVAFRVGLLLGGAITAMVLVLFGSLVRAPLPWWA
                     RWALVGAVLVLVALKEFGVVAMRFPENRRLVPEGVFRLGRHLGPLQFGIEMGTGARTYL
                     PSGLPYIAATAVLLTASLPQALLVGAGFGLGRALMTTANLNHPDDWHLAWTRHAALLTP
                     LLAGAFLVSLLGAVHAT"
     gene            complement(1390..1932)
                     /locus_tag="LV79_RS17090"
                     /old_locus_tag="LV79_003371"
     CDS             complement(1390..1932)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013224803.1"
                     /locus_tag="LV79_RS17090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003371"
                     /product="hypothetical protein"
                     /protein_id="WP_253837884.1"
                     /transl_table=11
                     /translation="MALTLEQIPDHESGPGRSVALSALKTTGKRRTVLRAITLGALTLG
                     TVALTFPRRAKAEVGPNALSGWDRTDCRDAYPVGYDEDQDTSGDHVNAYGACVGGAWRS
                     SDFCESGWHKYGTYTEGDVQVDHTAVSTTCGTTTMKNAWRWTTPDGKTYRCSDGFSTYW
                     GPDQAGYTYLTICRSRL"
     gene            complement(1904..2365)
                     /locus_tag="LV79_RS17095"
                     /old_locus_tag="LV79_003372"
     CDS             complement(1904..2365)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680410.1"
                     /locus_tag="LV79_RS17095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003372"
                     /product="hypothetical protein"
                     /protein_id="WP_253837886.1"
                     /transl_table=11
                     /translation="MTAFLVITWVAIVVLFLGLAAVLREVRLLRATVARDPGGFASAGA
                     EIDLGARFAGRVVVAADTGCPLCREVVGQLTGAVVLTHEPAEAWDTELEVVSDREAWRA
                     VSHLAPPVLMLVGTNGVVRRVALPVRAGQVDEVLDDWGVRGGAHAGTDS"
     gene            complement(2371..3051)
                     /locus_tag="LV79_RS17100"
                     /old_locus_tag="LV79_003373"
     CDS             complement(2371..3051)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680411.1"
                     /locus_tag="LV79_RS17100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003373"
                     /product="hypothetical protein"
                     /protein_id="WP_253837888.1"
                     /transl_table=11
                     /translation="MTTAQRLDLVAPSGARVAITLPGPEPVSSVAAAIRFAGGSYGTGF
                     QIGPRGYHAFAGTHVAPATTTDRFLVHGREVIVAEAHDGHSSTAALIGDHHELLTVYAG
                     PAPRHDRVFALFNSLRVTDSPRGMIVTPRRSTLLDTMSEHLVLAVRGYGQIAIPGPAQA
                     HTHIPTHAGARTDHGEVWKVPLAGSGHMFVLGFPAGVAEVQLAGHTQPHLDWLNAINVS
                     WATP"
     misc_feature    3039..3051
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            complement(3489..5075)
                     /locus_tag="LV79_RS17105"
                     /old_locus_tag="LV79_003374"
     CDS             complement(3489..5075)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006236527.1"
                     /locus_tag="LV79_RS17105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003374"
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="WP_253837892.1"
                     /transl_table=11
                     /translation="MRVIATAGHVDHGKSTLVRLLTGMEPDRWEQERRRGLTLDLGFAW
                     TSLPGVGDVAFVDVPGHERFVPTMLAGVGPAPAVLFVVSADSPWMPQAEEHLAAIDALG
                     VAHGLLVITRADLADPAPIRRDALARIARTSLGTVPSVVANDGVDGLRSAVADLVGRLP
                     VPDVDGDVRLWVDRSFTVAGAGTVVTGTLQAGTIRPGDELLLRGTPVRVRGVQALGEAR
                     SAVSAVARVGINLRGVDRSDVERGDALLTRGAWWDARVVDVTAAGLPRQVVLHIGAAAV
                     PARAHVLPTGSRLFLSRPLPLRVGDRVLLRNPGSHDIVGATVVDLDRLGRSPLFMASQR
                     KPLGRTGRLVAGEWYTDDWDSLAARARTELAAWRAGHPLEVGLPTETLRQKLRLPSVEL
                     VAPLLAGHDEVELPQSVVVAMAALSVDFATNPFGAPDATRLRQLGLGGREIAAAVRAGR
                     LLKLADGIVVLPGAPDRAAKVLSGLAQPFTTSQARQALGTTRRVVLPLLAFLDRTGVTK
                     RLPDDTRQLRQ"
     misc_feature    complement(4089..4091)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4176..4178)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4272..4274)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5092..5745)
                     /locus_tag="LV79_RS17110"
                     /old_locus_tag="LV79_003375"
     CDS             complement(5092..5745)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013228615.1"
                     /locus_tag="LV79_RS17110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003375"
                     /product="DUF899 family protein"
                     /protein_id="WP_253837893.1"
                     /transl_table=11
                     /translation="MNRPPVVSQQEWQAARDELLVKEKVLTHALDALAAERRRLPMFQV
                     RADHRFTAPDGGTVDFAALFDGKRQLVVYHFMLPAGADSICGGCATFTDNIPDLPHLAA
                     RDTRLILMAPAPQDEIEPVRARFGWTTPWYSSHGNGLYEEIGLGGGFALSVFLRDGDDI
                     FRTYATTSRGVDRLRTDFNLLDLTPYGRQEAWEDSPEGWPQTPTMQWLRLRDEY"
     gene            complement(5769..6746)
                     /gene="selD"
                     /locus_tag="LV79_RS17115"
                     /old_locus_tag="LV79_003376"
     CDS             complement(5769..6746)
                     /EC_number="2.7.9.3"
                     /GO_function="GO:0004756 - selenide, water dikinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0001887 - selenium compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="selD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417019.1"
                     /locus_tag="LV79_RS17115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003376"
                     /product="selenide, water dikinase SelD"
                     /protein_id="WP_253837895.1"
                     /transl_table=11
                     /translation="MTDRLTQYAHGGGCACKIPPGELERVVAGLHRTPTDPHGELIVGL
                     ENGDDAAVVGLGGDLALVATTDFFTPVVDDAYDWGRIAAANALSDVYAMGGRPVVALNL
                     LGWPRDVLPVELAGEVLRGGADVVASAGCHLGGGHSVDDPEPKYGLAVTGVVDVKHVMR
                     NSTGRAGLPLSLTKPLGLGVLNNRHKATGEVFPQAVEVMTTLNRDAAAAAVAAGVNCAT
                     DVTGFGLLGHLHKLARASGVTAVIDSTAVPYVEGAREALRDGFVSGGTRRNLDWVAPHV
                     SLGPDSLLLADAQTSGGLLIVGEIPGATVIGELLPSDCHTVVVR"
     tRNA            6782..6873
                     /anticodon=(pos:834723..834725,aa:Sec,seq:tca)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="LV79_RS17120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Sec"
     gene            6782..6873
                     /locus_tag="LV79_RS17120"
     gene            6895..8169
                     /gene="selA"
                     /locus_tag="LV79_RS17125"
                     /old_locus_tag="LV79_003377"
     CDS             6895..8169
                     /EC_number="2.9.1.1"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004125 - L-seryl-tRNA(Sec) selenium
                     transferase activity [Evidence IEA]"
                     /GO_process="GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="selA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680413.1"
                     /locus_tag="LV79_RS17125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003377"
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="WP_253837897.1"
                     /transl_table=11
                     /translation="MTDPRRQVPRTDAVLSAMTTEVDAHGRDAVKAAIHSAQDQVRAGI
                     IDPNQVISHARAALRTGPRPVINATGVLVHTNLGRAPLSTAARTAIQAAAGTTDVEFDL
                     ATGARRQRGRSTMDALRAAVPAADDAHVVNNNAAALLLCAIVLAGSRDIVVSRGELVEI
                     GDGFRIPDLLRSTGARLRGVGTTNRTTVRDYTDAISSDTGFVLKVHPSNFVVSGFTSTP
                     EVADLAGLGVPLVVDIGSGLLAPHPTLPDEPDVATMLRAGASLVTASADKLLGGPQAGL
                     LLGAAALIERLRRHPAARAMRVDKLTLAALEATLRGPRPPVVSALEADLTELGSRADRL
                     AAALSERGIDAVAVSSLAVVGGGGAPGVELPSAAVSLPESYAQPLRVGVTPVVGRIEQG
                     RCLLDLRSVMESDDDAILNAVLSVD"
     misc_feature    7318..7320
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7372..7374
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7411..7413
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8156..8941)
                     /locus_tag="LV79_RS17130"
                     /old_locus_tag="LV79_003378"
     CDS             complement(8156..8941)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.5"
                     /locus_tag="LV79_RS17130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003378"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_253837899.1"
                     /transl_table=11
                     /translation="MQVSVLGPLTAAGATASAAPSATKPKQVLALLALRANTVVSTARL
                     IDELWGARPPQSAVVTVQTYVLRLRRLLTPLSDVPIRSVLTTATGGYSLCLDDSQLDYG
                     RFRQRSALGVDALACGDFARAALLLHGALALWRGPALSDVRVGRLLEAHVTTMEQERLS
                     VLEQRIDADLRLGRHLGVLGELAGLTRELPLHENLHAQYMVALYQAGRRYQALEVFRQL
                     RQALADELGLSPTGWVERVHRAILTSDEVGLPILEVSRR"
     gene            complement(9144..10004)
                     /gene="pqqB"
                     /locus_tag="LV79_RS17135"
                     /old_locus_tag="LV79_003379"
     CDS             complement(9144..10004)
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020631257.1"
                     /locus_tag="LV79_RS17135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003379"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_253837901.1"
                     /transl_table=11
                     /translation="MRVVVLGTAAGGGLPQWNCACELCERSREGDPAVLPRLQDCVAVS
                     ATGRNWYLLNASPDLRAQIIATPELTPGPGRRQTPVRGALLTDAELDHTLGLALLREGP
                     LTVWAPPPVLDAVAVRPVVAHYQHWDWYPAEGVFRLDEGRLECAVFPLSGKRPRYARDA
                     ADAPDWVVAYRLTDVTTGGSLVYAPCLARWPEGFDEFVSGATLGLLDGTFLGPDEMSRT
                     TGRDDQVGMGHLPIAESLPLLGSTRWHYTHLNNTNPVVARDCAARGRIEAAGAAIAEDG
                     ARFDL"
     gene            complement(10001..11065)
                     /gene="pqqE"
                     /locus_tag="LV79_RS17140"
                     /old_locus_tag="LV79_003380"
     CDS             complement(10001..11065)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003079635.1"
                     /locus_tag="LV79_RS17140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003380"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_253837909.1"
                     /sec_met_domain="PF04055 (E-value: 3.4e-22, bitscore: 75.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.2e-10, bitscore:
                     37.7, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1e-11, bitscore: 41.2,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPQPPLGMLAELTHRCPLHCSYCSNPLDLVRRERELTTDQWRSA
                     LTQARELGVLQVHLSGGEPLARRDLPSLVSHAHGLGCYVNLVTSGLGLSEARMVDLARR
                     GVEHVQLSVQAADEDRADIIAGARAAKHKKAAAAAIRAAGLPLTINVVLHRRNHDQLGA
                     IIDLAEEWGADRLELANTQFYGWAMRNRAALMPTRAQLDAAEPVVRAARQRLAGRVEVV
                     YVLADYQDRHPKPCMHGWGARQLTVAPDGTVLPCPSAHVITGLRFDNVTERPLAEIWYE
                     SSSFNAYRGEDWMRDPCRTCDRRGVDLGGCRCQAFLLTGAAENTDPVCVLSPHHDVVEQ
                     AVVPAADVPFVMRR"
     gene            complement(11062..11331)
                     /gene="pqqD"
                     /locus_tag="LV79_RS17145"
                     /old_locus_tag="LV79_003381"
     CDS             complement(11062..11331)
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03859.1"
                     /locus_tag="LV79_RS17145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003381"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_253837911.1"
                     /sec_met_domain="PqqD_RRE (E-value: 1.3e-20, bitscore:
                     69.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.7e-11, bitscore: 40.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEWAPRLRRGARLGFDPVRRTPVVLYPEGVVVLNGTARAVLGAC
                     DGVATVPDIVAAMTARYRGVRPDDVLSLLRGLVARGVLHPEEAG"
     aSDomain        complement(11080..11319)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_LV79_RS17145_PqqD_RRE.1"
                     /evalue="3.40E-22"
                     /identifier="RREFam006.1"
                     /label="LV79_RS17145"
                     /locus_tag="LV79_RS17145"
                     /protein_end="84"
                     /protein_start="4"
                     /score="69.0"
                     /tool="antismash"
                     /translation="APRLRRGARLGFDPVRRTPVVLYPEGVVVLNGTARAVLGACDGVA
                     TVPDIVAAMTARYRGVRPDDVLSLLRGLVARGVLH"
     gene            complement(11328..12014)
                     /gene="pqqC"
                     /locus_tag="LV79_RS17150"
                     /old_locus_tag="LV79_003382"
     CDS             complement(11328..12014)
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336983.1"
                     /locus_tag="LV79_RS17150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003382"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_372495348.1"
                     /sec_met_domain="TIGR02111 (E-value: 2.6e-77, bitscore:
                     255.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGRDEFLGALRALEGRYWGTHPFHERMHAGALTPAELRTWAANR
                     WYYQAALPRKDAAIISNCPLPDVRRLWLDRIVYHDGAKEGEGGREDWLRLCEALGLDRA
                     EVLDERHVLPPVRFAVDAYVTFARTQPWVIAVASGLTEMFAGHLMRRRVVDVLAHYPWI
                     APQDLAYFTTRVEAVSGEGVQTVELVLEHCRTRAEQDAAVAALAFKCDVLWSMLSAIAG
                     GTAGNR"
     gene            complement(12015..12107)
                     /gene="pqqA"
                     /locus_tag="LV79_RS17155"
     CDS             complement(12015..12107)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019813815.1"
                     /locus_tag="LV79_RS17155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_253837915.1"
                     /transl_table=11
                     /translation="MGDERELWVVPEFEDYDTPMEVTAYVARQD"
     gene            complement(12460..16548)
                     /locus_tag="LV79_RS17160"
                     /old_locus_tag="LV79_003383"
     CDS             complement(12460..16548)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013508.5"
                     /locus_tag="LV79_RS17160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003383"
                     /product="hypothetical protein"
                     /protein_id="WP_253837917.1"
                     /transl_table=11
                     /translation="MTRRSGAKVAVVLLVLATLVSTGGPVLADPDPVDPAQVEVAGEAA
                     TATEVSDPASPTPATEESPVDPPAQTPPAEQSPSETAPVDEAPSGEPQEEPTIEEAPIV
                     EDAPSGQEADPRATVDLALSVYAPEAANAGAPISWTLTVRNNGPGSASSFTVTDTVPDS
                     VTGVSSPTAGCAVSGNVVSCGGGALAAGSSATFRINANTPTPFTFPLVNSASVATGPTD
                     SDANTGNNVATTVTTTAAPAPSVALLASASLNDTNGNGVGDVGENITYALEAHNQGNVT
                     LFNLSVQHNGAGTVTCASTTLSLGQSTTCSAPAHVVNAADVTAGQVVTTSTASATAPDG
                     ELVASAPTVTNIPTFAAAPAIELVRTANLIDTNGDTVGEVGEEIDYRFLVSNSGNVPLT
                     GVVVTGDDLVANPCAGVITTLQPNQTVECVRPTRYVITAQDAVNGSVAHTATASGVAPS
                     GTTVTSAPSTSSTPTFVPAPALTISQTYTPGDENSDGHIEAGETVRFQSTITNNGNVAL
                     SNVDVVIVTGSQSPSGCAPGLTVQAGATVVCTQSIPYVVTPQDAAAGVVTRTVRARGTS
                     AGGVVALSEPVTSSIPVFVPSPSIGLTHTATLIDANGNGLGDLGEQIQFSVTINNTGNV
                     VLTDVIVEGVLSGNAETLCPQAAMLPEASASCPRGLYTINQHDVDVGAVLGIGTAVGTA
                     PNGTRVRSVPITVNIPVFDPAPVLGLVKDDILVDANANGLADAGEAINYTFAVTNVGNV
                     TVTGLNIVDPLLTGTTCPKTTLIPQESTTCTSNAPHITTAADVAAAEVVNVATARGTAP
                     DSSTVISLESRTNTPTFVAVPGLALDKIAVLGDTNGNGLADLGENIQWSFLVVNNGTTP
                     LFRLHIVDPVAGVVTCPSTDLAVLAVTTCVATAPHQVTESDILLGEVTNTAIAVADLGD
                     AVQTQVVSPPDSTTTPTAGPNPGLTLTKRADLVDTNENDLADKGEIILYSFVLTNTGNL
                     TLSQLRVDDPKAGVVTCPVAILAPGASTTCTAAPYLVTGDDIAAGIVRNVAVGYGTPPV
                     GPEVQTPPAIAEVPIAYPGLTLDKIATLDDVDEDGFASVGETIVYTFVLVNIGNVPMTD
                     IKVDDPKAGVVTCPVTTLQPGETTTCSSEPYEVTEADVAIGVVHNEATASGQPPGTDPP
                     YVTPPDTEDVPTTEIVSGEDPNEAADAPAITLVKSAALRDTDGDDLADEGELIDYTFLV
                     TNTGDVALANIRVDDPKITGVVCPDTTLDPGESVTCAKLGYVVTAADIAAGTVHNVATS
                     SGDTGGGDTVTSQPSAVDVPVDDSIPGGGDAEEAEPAAQGGLAATGTTATIALFGWSLV
                     FLAAGVLVLFSSRDRRKKA"
     gene            complement(16883..17293)
                     /locus_tag="LV79_RS17165"
                     /old_locus_tag="LV79_003384"
     CDS             complement(16883..17293)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.5"
                     /locus_tag="LV79_RS17165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003384"
                     /product="ATP-binding protein"
                     /protein_id="WP_253837920.1"
                     /transl_table=11
                     /translation="MTTHQDLAVFSTTVPARAEHLAPLRRRVWGWLDGLRVPTPVRQDV
                     VLAAHEALSDAIDQPREGRDTTVSLLWDREVVVLTAVDHFTWTARAQHGDQPGERRLRA
                     IARIAERVDLDVDDEQGTLTAYFAVPPTDTGR"
     gene            complement(17426..18415)
                     /locus_tag="LV79_RS17170"
                     /old_locus_tag="LV79_003385"
     CDS             complement(17426..18415)
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014869.5"
                     /locus_tag="LV79_RS17170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003385"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_253837922.1"
                     /transl_table=11
                     /translation="MSLLAATPSAAQPSGTGTGAWNQNPVPVVTTLSGSTYVMRDPRWI
                     GLDCVDAVTGVVFSGPDDVWGNGDPTDRETGCVDAYYAAQNFQRMTVRWLGRNGAEGNG
                     RPGFGLRVGDSRLGLGVVAGRISVGRNSAGQWVGSLDLIGREYGRLIDQTTPGGLSRNG
                     TGEFIADAFGTANEWFAGQTAGDVPDLLVGERPSTPRDMSNPAATGGINCYTSAVPTAE
                     VYSAAGVGNHWFALLAAGSRPTNGLPPSPTCEGTTVTGIGVDRAIRILYTAMQFKVSGM
                     TYQKYRIATLKAAQLLTPGNCTDYNAVKAAWNAVNVPAQVGEPTVVCD"
     misc_feature    18416..18434
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.68"
                     /tool="antismash"
     misc_feature    complement(18614..18629)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.31"
                     /tool="antismash"
     gene            18656..19297
                     /locus_tag="LV79_RS17175"
                     /old_locus_tag="LV79_003386"
     CDS             18656..19297
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020636677.1"
                     /locus_tag="LV79_RS17175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003386"
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="WP_372495349.1"
                     /transl_table=11
                     /translation="MGIRRAATAVVAMTGALLASTVLVAAPAMAHGSMGNPVSRIYQCF
                     TEGPENPRSAACKAAVQVGQSWPIYDWDEVNQPNANGNSRQIIPDGKLCSAGRDKYKGL
                     DLPRADWPATTLPTGAYTFTYKATAPHPGTFELYVTKQGYDPTKPLKWSDLEATPFYKQ
                     LNPPRASGSYQLKATIPSGRTGRHLIFSIWQRHKPDSGEAFYSCSDVLFN"
     gene            complement(19338..19763)
                     /locus_tag="LV79_RS17180"
                     /old_locus_tag="LV79_003387"
     CDS             complement(19338..19763)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025786.5"
                     /locus_tag="LV79_RS17180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003387"
                     /product="Imm1 family immunity protein"
                     /protein_id="WP_253837924.1"
                     /transl_table=11
                     /translation="MTKPDEPITHRGAIAIDEIPAGVDVVAEVCALNSAGVDVPWLWEF
                     TRTRQSSPNDEQPILTAGVNNSVGVLEWRQGQDVWVPASGANPDWTDYAAAGLHPYAVR
                     PHTGVPIDAVYAAIMEFITTGDRPAGIEWRGGISIFD"
     gene            19940..20854
                     /locus_tag="LV79_RS17185"
                     /old_locus_tag="LV79_003388"
     CDS             19940..20854
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013775.5"
                     /locus_tag="LV79_RS17185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003388"
                     /product="phosphotransferase family protein"
                     /protein_id="WP_253837925.1"
                     /sec_met_domain="APH (E-value: 1.3e-18, bitscore: 63.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRWLTECSVDTVRDALRVVAPGLAELPITLPDLVGRDEPLWMASS
                     AAVGEEFVAKVAWSAPAARRLAHEIGVLTALSVPFMPEVVASSTEPVLLVTRRMPGKSL
                     FAVVDSIDRDHAGRQLAQFLVALHDPSTRAAVERALGPLPAPRAEASTDEIRARLGRWV
                     RPDQHAAVTTWCAWADEVLAEPRPSVLVHGDLHGDNQVWNGDRLSLVVDFETTSAAEPE
                     YDLRAFPSTGPDCELLTATTQHYEHLSGRSLSLDRIMAWHLRTTLDDLLWRSEARVPLP
                     GHHSPTTWINDLTTRFAKLQIGP"
     misc_feature    19949..19964
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.36"
                     /tool="antismash"
     gene            complement(20885..21256)
                     /locus_tag="LV79_RS17190"
                     /old_locus_tag="LV79_003389"
     CDS             complement(20885..21256)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS17190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_003389"
                     /product="hypothetical protein"
                     /protein_id="WP_253837927.1"
                     /transl_table=11
                     /translation="MDFIGIQPFGETSQIDVVLDELGEIDLRNDGAVVGIRFVAGAKAL
                     SVVVDFSIEGRAVSLEFVEAEVIQVEPDLPIIVDPTYGHALLIGLWAWTAPGGRRGCTV
                     DTTMMSIDLYATRVIANVE"
     misc_feature    21258..21271
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.49"
                     /tool="antismash"
     gene            complement(21425..21706)
                     /locus_tag="LV79_RS17195"
                     /old_locus_tag="LV79_003390"
     CDS             complement(21425..21706)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS17195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_003390"
                     /product="hypothetical protein"
                     /protein_id="WP_253837929.1"
                     /transl_table=11
                     /translation="MATLAKVLVLAVLLTGMVQTPASAADYTVPRSATVVAVGQAPAIA
                     KANAQRRARAEVLEAGVDCVDWVVTEVASGWVPPKYYHTAKATALCVS"
     misc_feature    complement(21730..21745)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.73"
                     /tool="antismash"
     misc_feature    complement(21882..21893)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
ORIGIN
        1 gaccgtccgc catgctccct cctcgcgccg cccgaccgcg aacaccgcct cggcggcgcc
       61 gcgcgcgtgt agccgcaacg cctcctctgt gatccgctgc ctgccgagaa cctcacggac
      121 ctcggggtgt gtcagcgcct cgtcgaggag gctgtcgaag aaggcgtctc ggtcgagtcg
      181 atccgggtgc cacggctgcg ggtagtcggc cacaaccgta tgtgcgtgga cctggccgtc
      241 gcgttacggg tggcggccag gtccggggtg ggtcagcgga actcgtggac cagttcgatg
      301 gggccgacga ggtgggtgtt gaactcggcg aggtcggcgg cggggaccca cagctcgagg
      361 atcgtccggc caccggcctg ttggacgggg tagcgctgga ggtagtcggt gtcgacgtgg
      421 aagcgggtca cgtagccgac gccgtggtgg gggacgttcc agtcgcgggc gatcttgatg
      481 gcgtagtcct cgttgaggac cgggtagaag atcggctggt ccgggcgccg cggcggccag
      541 gcgcgccagt cggcctggcg gacgaggtcg agttcctcgg ggccggtggg acgccacagc
      601 acggtggtgg ggttctgggc cacggtgcac ctctcctcgg ttcgcggaag gcaacctatc
      661 gagcgctcac gggccgtggc caagggtttt aggtcgcgtg gacggcaccg agcagggaga
      721 cgaggaacgc gcccgccagc agtggggtga ggagggcggc gtggcgggtc cacgcgaggt
      781 gccagtcgtc ggggtggttg aggttggcgg tagtcataag agcgcggccg agtccgaagc
      841 ccgcgccgac gagcagtgcc tgcgggagcg acgcggtgag caggacggcg gtggcggcga
      901 tgtagggcag gccactgggc aggtaggtgc gggcgccggt gcccatctcg atgccgaact
      961 ggagcgggcc caggtgtcgg ccgaggcgga agacgccctc gggcaccagc cgccggttct
     1021 cggggaagcg catggccacc acgccgaact ccttgagcgc gacgagcacc agcaccgcgc
     1081 cgaccaacgc ccaccgtgcc caccagggca gcggggcgcg cacaagcgac ccgaacagga
     1141 ccagcaccat cgcggtgata gcgccaccga ggaggagtcc gacgcggaac gcgacagcgg
     1201 gagaacctcg ccagaccggc gagctcagca cgtgtgctga gttccgactt caagtggagc
     1261 ccgaggtcgc gaacccggct gttgcaccga ggaacaccca tggcacccac agcgccccac
     1321 cgacggccgc gagagttagc cctaccgcga ggatgatggg gtgccaccag ctacggggtt
     1381 ggcgcatggt caaagccggg agcggcagat ggtcaggtag gtgtatccgg cctggtcggg
     1441 gccccagtag gtgctgaagc cgtcggagca gcggtaggtc ttgccgtcgg gggtggtcca
     1501 gcgccaggcg ttcttcatgg tcgtggtgcc gcaggtggtg gagacggccg tgtggtcgac
     1561 ctggacgtcg ccctcggtgt aggtgccgta cttgtgccag ccggactcgc agaagtcgct
     1621 gctgcgccag gcgccgccga cgcacgcgcc gtaggcgttg acgtggtcgc cgctggtgtc
     1681 ttggtcctcg tcgtagccga cggggtaggc gtcgcggcag tcggtccggt cccagccgct
     1741 cagggcgttc gggccgacct ccgccttggc gcgacggggg aaggtcaggg cgacggtgcc
     1801 gagtgtgagg gcgcccaggg tgatcgcgcg caggacagtg cggcgcttgc cggtggtctt
     1861 gagcgcgctg agcgcgaccg acctgccggg gccggactcg tggtcaggaa tctgttccag
     1921 cgtgagcgcc accgcgcacc ccccagtcgt cgagcacctc gtccacctgc ccggcccgga
     1981 ccggtagcgc tacccgtcgc accactccgt tagtgccgac cagcatcaac accggcggcg
     2041 ccaagtgcga taccgcccgc cacgcctcgc ggtcgctgac gacctccagc tcggtgtccc
     2101 acgcttccgc cggttcgtga gtcagtacta ccgcgccggt caattgcccg acgacctcgc
     2161 ggcacagcgg gcatcccgtg tccgccgcga ccacgacccg ccccgcgaac cgcgccccca
     2221 agtcgatctc ggccccagcg gaggcgaacc cacccgggtc cctggcgacg gtcgcccgca
     2281 gtagccgcac ctcgcgcagc actgccgcca accccaggaa caacaccacg atcgcgaccc
     2341 acgtgatcac caggaacgcg gtcatcgggg tcatggggtg gcccaggaga cgttgatggc
     2401 gttgagccag tcgaggtggg gttgggtgtg gcccgcgagt tggacctcgg cgacgcccgc
     2461 ggggaagccg aggacgaaca tgtggccgga cccggccagc ggcaccttcc acacctcgcc
     2521 gtggtcggtg cgggcgcccg cgtgggtggg gatgtgggtg tgggcctggg cggggccggg
     2581 gatggcgatc tggccgtagc cgcggaccgc caggaccagg tgctcgctca tggtgtcgag
     2641 cagggtggag cgccgggggg tgacgatcat gccgcggggg ctgtcggtca cgcgcaggga
     2701 gttgaacagg gcgaacacgc ggtcgtgacg gggcgcgggg cctgcgtaga cggtgaggag
     2761 ttcgtggtgg tcaccgatca gcgcggctgt ggaggagtga ccgtcgtggg cttcggcgac
     2821 gatcacttcg cggccgtgga ccaggaagcg gtcggtggtt gtggcgggcg cgacgtgggt
     2881 gcccgcgaag gcgtggtagc cgcgggggcc gatctggaag ccggtgccgt acgagccgcc
     2941 cgcgaagcgg atggcggcgg ccacgctgga caccggttcg gggccgggga gcgtgatggc
     3001 gacccgggca ccgctgggcg ccaccaggtc tagccgctgt gccgtggtca cgcggcatga
     3061 cgctagagca gcgggaacac gcgatcaact agttccaccg aatgtcggat tccctttccc
     3121 agtagggcgt ctagcgtgat gtcgtgctgg gaaccgtcgc cgctggtggg gcgatcctgt
     3181 tgttgctggc ggcgttcgac cacgctaccg accgtcggtg gctggcgggt ctagaggtag
     3241 cggttgccgc gtcagtgttc ggaacccgtt atgccgtagt ggttctctat gcggctttca
     3301 cgttctatct cgttgaccgt aagagacgca gacctggtgc tccatgtggt tgcttccgag
     3361 ccgagggccc gatcacgtgg ctgaccgtgg ctagagcggt gttcttcgcc gtaggggccg
     3421 ctgtggagcc agaactgccg gtcgcggtag cgctagcggg tgggttcgtg ctggcgatgg
     3481 tgtggtggct actgcctcag ctgacgggtg tcgtcaggca gccgcttggt cacgcccgtg
     3541 cggtcgagaa acgccaatag cggcaacacg acgcggcgag tcgtaccgag tgcttggcgt
     3601 gcctggctcg tggtgaacgg ctgcgcaaga ccagacagga ccttcgccgc ccgatccggc
     3661 gcgcctggca acacgacgat gccgtcggcg agcttcagca gccgcccggc ccgcacggct
     3721 gccgcgatct cgcggcctcc tagacccaac tgccgcaacc gagtcgcgtc cggagcgccg
     3781 aacgggttgg tcgcgaagtc cacactcaac gcggccattg cgaccacgac ggactgcggt
     3841 agctctacct cgtcgtgacc ggccaacagt ggcgccacga gttcgacgct gggcagcctt
     3901 agcttctggc gcaacgtctc cgtcggtagc cctacctcga gcggatggcc agcacgccaa
     3961 gcagccagct ctgtccgggc ccgtgccgcc aacgagtccc agtcgtcggt gtaccactcc
     4021 cccgcgacca accgtcccgt gcgccccaac ggcttgcgtt gactggccat gaacagcggt
     4081 gaccggccta agcggtccag gtcgacaacc gtggcgccga cgatgtcatg gctaccggga
     4141 ttgcgcagca gcacacgatc ccccacacgc agcggtaagg gccgcgagag gaacagcctg
     4201 ctcccggtag gcagcacgtg cgcgcgggca ggaacagcgg cagccccgat atggagcacg
     4261 acctgtcggg gtaaaccggc ggcggtgacg tcaacgacgc gggcatccca ccacgcgcct
     4321 ctagtcagca acgcgtcgcc gcgttcgacg tcggaccggt ccacaccgcg caggttgatc
     4381 cccacacgcg cgaccgccga caccgccgaa cgcgcctccc ccagcgcttg caccccgcgc
     4441 acccgcaccg gggtcccccg cagcagaagc tcgtcgcccg ggcggatcgt gcccgcctgc
     4501 agggtccccg tcacgacggt gcccgccccc gcgacggtga acgaccggtc cacccacaac
     4561 cggacatcac cgtcgacatc gggcaccggt agccgtccga ccaggtccgc caccgccgag
     4621 cgcagcccgt caaccccgtc gttggccacg accgagggca ccgtccccag cgaggtccgc
     4681 gcgatcctgg ccagcgcgtc ccggcggatc ggcgcgggat cggccaggtc ggcgcgggtg
     4741 atcaccagca gcccgtgcgc caccccgagc gcgtcgatgg cggccaggtg ttcctcggcc
     4801 tgcggcatcc acggcgagtc ggcggacacg acgaacagca cggcgggcgc ggggccgacc
     4861 ccggcgagca tcgtcgggac gaaccgctcg tgcccgggga cgtcgacgaa cgcgacatcg
     4921 cccacgcccg gcaacgaggt ccaggcgaac cccaggtcga gtgtcagccc ccggcggcgc
     4981 tcctgctccc agcggtcggg ttccatgccg gtgagcagcc ggacgagggt cgacttgccg
     5041 tggtcgacgt gcccggccgt cgcgatcacc cgcactcgac cacccccggg gctagtactc
     5101 gtcgcgcagg cgcagccact gcatggtggg ggtctgcggc cagccctcgg gcgagtcctc
     5161 ccacgcctcc tgccgcccgt acggggtcag gtcgaggagg ttgaagtcgg tccgaagccg
     5221 gtcgacgccg cgcgaggtgg tggcgtaggt gcggaagatg tcgtcgccgt cgcgcaggaa
     5281 caccgacagg gcgaagccgc cgccgagacc gatctcttca tagaggccgt tgccgtgact
     5341 ggagtaccag ggcgtggtcc agccgaagcg ggcgcgcaca ggctcgatct cgtcctgggg
     5401 cgcgggtgcc atgaggatca gtcgggtatc gcgggcggcg aggtgcggga ggtcggggat
     5461 gttgtcggtg aacgtggcgc agccgccaca gatcgagtcg gcgcccgcgg gcagcatgaa
     5521 gtggtagacg accagttgac gtttaccgtc gaacagcgcc gcgaagtcca ctgtgccgcc
     5581 gtcgggcgcg gtgaaccggt ggtcggcgcg cacctggaac atgggcaggc gcctgcgttc
     5641 ggcggccaag gcgtccagcg cgtgggtcag caccttctcc ttcaccagca gctcgtcgcg
     5701 cgcggcctgc cattcctgct gggacacgac cgggggtcgg ttcacgggtc ctccttcgtc
     5761 gggagcgttc atcgcaccac gacggtatga cagtcgctgg gcaacagttc gccgatgacg
     5821 gtcgcaccgg ggatctcgcc gacgatcagc agtccgccgg aagtctgggc gtcggcgagg
     5881 agaagtgagt ccggtccaag tgagacgtgt ggcgctaccc agtccaggtt gcgtcgagtg
     5941 ccgccgctga cgaaaccgtc gcgtagagcc tcgcgcgcgc cctcgacgta agggacggcg
     6001 gtggagtcga tgaccgcggt gacgccgcta gcacgtgcca gcttgtggag gtgtccgagc
     6061 agaccgaacc cggttacgtc tgtcgcgcag ttgaccccgg cggctaccgc tgctgctgcg
     6121 gcatcccggt tgagcgttgt catcacctcg actgcttgcg ggaacacctc cccggtcgcc
     6181 ttgtggcggt tgttgagcac gccgagccct agaggcttgg ttagcgatag gggcaaaccc
     6241 gcgcgaccag tcgagttccg catgacgtgc ttgacgtcga cgacaccagt aacagccagc
     6301 ccgtacttgg gctccgggtc gtcaacgctg tgcccgcccc ctagatgaca acccgcggag
     6361 gccacgacgt ccgcaccccc gcgcagaacc tcgcccgcca gctctaccgg cagcacgtcg
     6421 cggggccagc ccagcaggtt caacgccacc accggccgtc cacccatggc gtacacatcg
     6481 gacagggcgt tcgcggcggc gatgcggccc cagtcgtagg cgtcatcgac cacgggggtg
     6541 aagaagtccg tggtggccac cagcgcgaga tcaccaccga gccccaccac cgcggcgtcg
     6601 tccccgttct ccaagccgac gatcagctca ccgtgcgggt cggtcggggt gcggtgcagc
     6661 ccggcgacga cccgctccaa ctccccaggc gggatcttgc acgcgcagcc gccaccgtgg
     6721 gcgtactggg tcagccgatc ggtcacaccc ggcagtgtgt catgatcact gagtgttcag
     6781 gggaggcgtc tccggcctgg tggccggctc ggtcttcaac accggtgagc gacaggtcct
     6841 gccgctggcg ggttcgattc ccgtccgcct ccgccgcccg gtcccggtcg accggtgacc
     6901 gatccacgca ggcaggtgcc gcgcaccgac gccgtcctca gcgcgatgac caccgaggtc
     6961 gacgcccacg gccgagacgc cgtgaaggcc gcgatccact ctgcccagga ccaggtccgc
     7021 gccgggatca tcgatcccaa ccaggtgatc agccacgcca gagcggccct gcgcaccggg
     7081 ccgcgtccgg tcatcaacgc caccggggtc ttggtgcaca ccaacctcgg ccgcgctccc
     7141 ctgtcgaccg ccgcgcgtac cgcgatccag gcagcggcgg ggacgacaga cgtcgagttc
     7201 gacctcgcga ccggggcacg acgccaacgc ggccgcagca cgatggacgc gctaagagcg
     7261 gccgtgcccg cagccgacga cgcgcacgtc gtcaacaaca acgccgccgc tttgctctta
     7321 tgcgcgatcg tcctcgcggg cagcagggac atcgtggtca gcagaggcga gttagtggag
     7381 atcggcgacg ggttccgcat ccccgacctc ttacgctcga ccggcgcgcg cctgcgtggg
     7441 gtcggcacca cgaaccgcac caccgtgcgc gactacaccg acgcgatcag cagtgacacc
     7501 gggttcgtgc tcaaggtcca cccgtccaac ttcgtcgtct ccgggttcac cagcacgccc
     7561 gaggtcgcgg acctggccgg gctgggggtg ccgctggtgg tcgacatcgg ctccggcctc
     7621 ctcgccccgc acccgacgct gccggacgag cccgacgtgg ccacgatgtt gcgggcgggt
     7681 gcctcactgg tcacagcgag cgcggacaag ctgctcggcg gcccgcaggc cggtctgctg
     7741 ctgggcgcgg cagcgctcat cgagcggctg cgcaggcacc cggcggcccg cgcgatgcgc
     7801 gtcgacaagc tgaccctggc agccctcgag gcaacactgc gcggaccgcg cccacccgtc
     7861 gtctccgcgc tagaagccga cctcaccgaa ctcggcagcc gagccgaccg gcttgcggcg
     7921 gcactgtccg agcgcggtat cgacgcggtc gccgtgtcgt ctctggcggt ggtcggcggc
     7981 ggaggcgccc cgggcgtaga gctccccagc gctgcggtga gcttgcctga gtcttacgcg
     8041 caacctctcc gagtcggcgt gacgcccgtg gtcggacgga tcgaacaggg ccgttgcctc
     8101 ttggacctcc gcagcgtcat ggagtccgac gacgacgcga tcctcaacgc cgtcctcagc
     8161 gtcgactgac ctcgagtatc ggcagcccta cctcgtccga cgtcaggatc gcccggtgca
     8221 cgcgttcgac ccaacctgtc ggcgatagcc ccaactcgtc tgccagggcc tgtcggagct
     8281 gccggaacac ctccagcgcc tggtagcggc gaccggcttg atagagggcg accatgtact
     8341 gggcgtgcag gttctcgtgc aacggcagct ccctggtgag cccagccaac tcccccagca
     8401 cgcccaggtg ccgcccgagc cgcagatccg catcgatccg ctgctcgagc acgctgagcc
     8461 gctcctgttc catcgtcgtc acatgcgcct ccagcaaccg tcccactcgg acatccgaca
     8521 gcgccggacc acgccacagg gccaacgcac cgtgcagcag caacgcggct ctggcgaagt
     8581 ccccgcaggc gagcgcgtcg acgccgaggg ccgagcgctg ccggaaccgc ccgtagtcga
     8641 gctgggaatc gtccaggcac aacgagtacc cgccggtcgc ggtggtgagg accgagcgga
     8701 tgggaacgtc cgacagcggt gtcaacaacc gacgtagacg caaaacatag gtctgcacag
     8761 tcacaacggc gctctgcggc ggccgggcgc cccacagctc gtcgatgagc cgagcggtcg
     8821 acacgacggt gttggcgcgc aacgcgagca gggcgaggac ctgtttgggc ttggtggcgc
     8881 tgggcgcggc actggcggtg gcaccggcgg cggtgagcgg accgagcacg ctgacctgca
     8941 tgagtaaccc ctggatggtg gcgggacacg acctggcggg gacggggcag caggacaccg
     9001 gaccgccgtc gttgccgggt accgtgacgg cggtccagtc agtggaacct tcccgatccc
     9061 ggcagtcaat cggctacgcg tggagacggc aaccgccatt ggcccctgac ttcaccccgg
     9121 ccggtcggcg taggctccgc cgatcacagg tcgaaccgcg cgccgtcctc ggcgatcgcg
     9181 gccccagccg cctcgatccg cccccgcgcg gcgcagtccc gcgcgacgac cgggttggtg
     9241 ttgttcaggt gcgtgtagtg ccagcgggtc gatcccagca gcggcaacga ctcggcgatc
     9301 ggcaggtgcc ccatcccgac ctggtcgtcg cggccggtcg tccgcgacat ctcgtccgga
     9361 ccgaggaagg tgccgtcgag cagcccgagg gtcgcgccgg agacgaactc gtcgaagccc
     9421 tcgggccacc tggccaggca cggcgcgtac accaacgacc cgccggtggt gacgtcggtg
     9481 agccggtagg cgaccaccca gtccggcgcg tcggcggcgt cccgcgcgta ccgcggtcgc
     9541 ttgccggaca acgggaacac cgcgcactcc agccgaccct cgtccagccg gaacacgccc
     9601 tcggccgggt accagtccca gtgctggtag tgcgcgacga ccggccggac cgcgacagcg
     9661 tcgagcaccg gcggcggcgc ccacaccgtc agcggaccct cgcgcagcag ggccaagccc
     9721 agggtgtggt caagttcggc gtcggtcagc aaggccccgc gcaccggggt ctggcgccta
     9781 ccggggccgg gcgtcaactc gggtgtggcg atgatctggg cgcgcaggtc gggggaagcg
     9841 ttgagcaggt accagtttcg gccggtagcg ctaacggcca cgcagtcctg caagcgtggg
     9901 agcacggcag ggtcaccttc gcgggaacgc tcgcagagct cacacgcgca gttccactgc
     9961 ggcaaaccgc ccccagccgc cgtaccgagg accacgaccc tcatcggcgc atcacgaacg
    10021 gcacgtccgc cgcgggtacg accgcctgct cgaccacgtc gtggtgcggg gacagcacgc
    10081 acaccgggtc ggtgttctcc gccgccccgg tcagcaggaa cgcctggcag cggcatccac
    10141 ccaggtcgac tccccgtcga tcgcacgtgc ggcacgggtc gcgcatccag tcctcgcccc
    10201 ggtaggcgtt gaacgacgat gactcgtacc agatctcggc cagcgggcgc tcggtcacgt
    10261 tgtcgaagcg cagcccggtg atcacgtgcg ccgacgggca gggcaacacg gtgccgtcag
    10321 gcgcaacggt gagctgacgg gcgccccacc cgtgcatgca cggcttcggg tgccggtcct
    10381 ggtagtcggc gagcacgtag accacctcca cccggcccgc gagccgctgc ctggccgccc
    10441 gcaccaccgg ttcggcggcg tcgagctggg cgcgggtcgg catcaacgcg gcccggttgc
    10501 gcatcgccca cccgtagaac tgggtgttgg ccaactccaa gcggtctgcg ccccactcct
    10561 ccgccaggtc gatgatcgcg ccgagctggt cgtggttgcg gcggtgcagg acaacgttga
    10621 tggtcagcgg cagcccagcg gcccggattg cggccgcggc ggccttcttg tgcttggccg
    10681 cccgcgctcc cgcgatgatg tcggcccggt cctcgtccgc ggcctgcacc gagagctgca
    10741 cgtgctcgac accgcgccgg gccaggtcga ccatgcgcgc ctcggacaga ccgagtccgc
    10801 tggtgaccag gttgacgtag caaccgaggc cgtgcgcgtg gctgaccaag ctgggcagat
    10861 cacgccgggc cagcggctcg ccgccggaga ggtgcacctg cagcacgccg agctcccggg
    10921 cctgggtcaa cgccgagcgc cactggtcgg tggtcaactc ccgctcgcgg cggaccaggt
    10981 cgagcgggtt ggagcagtac gagcagtgca gcgggcagcg gtgggtcagc tcggcgagca
    11041 tgccgagcgg gggctgcggg gtcatccggc ctcctcgggg tgcagcacgc cgcgcgcgac
    11101 caacccgcgc agcagggaca gcacgtcatc ggggcgcaca ccgcggtagc gcgcggtcat
    11161 cgccgcgacg atgtcgggca ccgtcgccac gccgtcgcac gcgccgagca cggcccgggc
    11221 ggtgccgttg aggaccacga cgccctcggg gtagagcacg accggggttc gccgcaccgg
    11281 gtcgaacccc agccgcgctc cgcgccgcaa ccggggcgcc cactcgctca ccggtttccc
    11341 gccgtcccgc ctgcgatggc gctgagcatg gaccagagca catcgcactt gaacgcgagc
    11401 gcggccacgg cggcgtcttg ctctgccctc gtccggcagt gctctaggac gagttcgaca
    11461 gtttggaccc cttcgccgga cacagcctct acgcgcgtgg tgaagtacgc gaggtcttgc
    11521 ggcgcgatcc aggggtagtg cgcgaggaca tcgaccaccc gacggcgcat caggtgaccg
    11581 gcgaacatct cggtgagccc ggaggccacc gcgatcaccc agggctgcgt tcgcgcgaag
    11641 gtgacgtaag cgtcgaccgc gaaccgcacc ggtgggagga cgtgccgctc gtcgagcacc
    11701 tcggcgcggt cgagacctag cgcctcacag agccgcagcc agtcctcgcg gccgccttcg
    11761 ccctccttgg cgccatcgtg atagacgatc cggtccagcc agagcctgcg gacatccggg
    11821 agcgggcagt tgctgatgat cgcggcgtcc ttgcggggca acgcggcctg gtagtaccac
    11881 cggttcgccg cccaggtccg cagctcggca ggggtaagag ctcccgcgtg catgcgctcg
    11941 tggaatggat gagtccccca gtaccggccc tctagcgccc gcaacgcccc gaggaactcg
    12001 tcccgaccca acacctagtc ctgccgcgcc acgtacgcgg tcacctccat cggcgtgtcg
    12061 tagtcctcga actccggcac cacccacaac tcccgctcgt cacccatgcc cgctcctctc
    12121 ggttagcgcc aactccccca gcttgacccg gtcccttgga gccctcttgg acccctgctg
    12181 gaccggcccc tctcgacccg agcatccacg ccgaaccggc ttccatgtcg tcctggcgct
    12241 tttgtcttgt tcttgttttg tggctctgac ctcgtgagca agagctagta aatatctcga
    12301 tagtacataa tggataccga gaccgagact gtaaacccgg gttggaccgg gggcgatcga
    12361 ccttcggaca ggcggaaacg ctgtggcccg cgggggtgga gatccccgcg ggccacagcg
    12421 tcaccacatc cggcgtggcc ggacgcgtgc tttctgcggt tatgccttct tgcgcctgtc
    12481 cctgctgctg aacaggacca gcacgcccgc cgcgaggaac accagggacc acccgaacag
    12541 ggcgatggtc gcggtggtgc cggtggcggc gagaccaccc tgggcagcgg gttcggcttc
    12601 ctcggcgtcg ccgccacccg ggatggagtc gtccacgggg acgtcgaccg ccgagggctg
    12661 ggaggtcacc gtgtcgccgc cgccggtgtc accggaggag gtggcgacgt tgtggacggt
    12721 gcccgcggcg atgtcggccg cggtgaccac gtagcccagc ttggcgcagg tgaccgactc
    12781 gcccgggtcg agcgtggtgt ccgggcagac gacgccggtg atcttcgggt cgtcgacccg
    12841 gatgttcgcc agcgccacgt caccggtgtt ggtgaccagg aaggtgtagt cgatcagctc
    12901 gccctcgtcg gcgaggtcgt cgccgtcggt gtcgcgcagc gcggccgact tgaccagggt
    12961 gatcgccggg gcgtccgcgg cctcgttcgg gtcctcaccg gagacgatct cggtggtggg
    13021 cacgtcctcg gtgtcgggcg gcgtcacgta cggcgggtcg gtgcccggcg gctggccgga
    13081 cgcggtcgcc tcgttgtgca cgaccccgat cgcgacgtcg gcctcggtga cctcgtaggg
    13141 ctccgaggag cacgtcgtgg tctcccccgg ctgcagggtc gtcaccgggc aggtgaccac
    13201 accggccttc gggtcgtcga ccttgatgtc ggtcatcggc acgttgccga tgttgaccag
    13261 cacgaaggtg tagacgatgg tctcaccgac gctggcgaag ccgtcctcgt ccacgtcgtc
    13321 gagggtggcg atcttgtcca gggtcagacc cgggtacgcg atcgggacct cggcgatggc
    13381 gggcggggtc tgcacctcgg ggccgaccgg cggggtgccg tagccgaccg cgacgttgcg
    13441 cacgatcccg gcggcgatgt cgtcaccggt gaccaggtac ggcgccgcgg tgcaggtggt
    13501 gctggcgccg ggggccagga tcgccaccgg gcaggtcacc accccggcct tggggtcgtc
    13561 cacccgcaac tggctcagcg tcaggttgcc ggtgttggtg agcacgaacg agtacaggat
    13621 gatctcgccc ttgtcggcga ggtcgttctc gttggtgtcg accaggtccg cccgcttggt
    13681 cagggtcaac ccggggttcg ggcccgcggt gggcgtggtg gtcgagtcgg gcggtgagac
    13741 gacctgtgtc tgcacggcgt caccgaggtc ggcgacggcg atggcggtgt tggtgacctc
    13801 accgagcagg atgtcgctct cggtgacctg gtgcggcgcg gtggccacgc aggtggtgac
    13861 ggcgaggacc gccaggtcgg tgctcgggca ggtgaccacc ccggccaccg ggtccacgat
    13921 gtgcagccgg aacagcggcg tggtgccgtt gttgaccacc aggaacgacc actggatgtt
    13981 ctcgcccagg tcggcgaggc cgttgccgtt ggtgtcgccg agcaccgcga tcttgtcgag
    14041 cgcgaggccc gggaccgcga cgaaggtcgg cgtgttggtc cgcgactcca acgagatgac
    14101 ggtggagctg tccggcgcgg tgccccgggc cgtcgcgacg ttgacgacct cggctgcggc
    14161 cacgtcggcg gcggtcgtga tgtgcggggc gttggacgtg caggtggtgc tctcctgcgg
    14221 gatcagcgtc gtcttcgggc aggtcgtgcc ggtgagcagc gggtcgacga tgttcaggcc
    14281 cgtgaccgtc acgttgccga cgttggtcac cgcgaaggtg tagttgatgg cctcgcccgc
    14341 gtcggcgagc ccgttggcgt tggcgtcgac gaggatgtcg tccttgacca ggcccagcac
    14401 cggcgccggg tcgaacaccg ggatgttgac ggtgatcggg accgagcgga cccgggtgcc
    14461 gttgggggcc gtgccgaccg cggtgccgat gcccagcacc gcgccgacgt cgacgtcgtg
    14521 ctggttgatc gtgtagagcc cgcgcgggca ggaggcactg gcctccggga gcatggccgc
    14581 ctgcgggcac agcgtctccg cgttgccgct gagcacgccc tcgacgatga cgtcggtcag
    14641 caccacgttg ccggtgttgt tgatggtgac gctgaactgg atctgctcac cgaggtcgcc
    14701 gaggccgttg ccgttggcgt cgatgagggt cgcggtgtgc gtgaggccga tcgacgggct
    14761 cggcacgaac accgggatgc tggaggtgac cggctcggac agcgccacga cgccgcccgc
    14821 cgaggtgccc ctggcccgga ccgtgcgggt gaccacaccg gccgcggcgt cctggggtgt
    14881 cacgacgtac gggatggact gggtgcagac cacggtggca ccggcctgga ccgtgaggcc
    14941 cggcgcgcag ccggacgggg actgcgaccc ggtgacgatg acgacgtcga cgttgctgag
    15001 cgccacgttg ccgttgttgg tgatggtcga ctggaaccgg acggtctcac cggcctcgat
    15061 gtggccgtcg ctgttctcgt cgccgggggt gtaggtctgc gagatggtga gcgccggggc
    15121 gggcacgaag gtcggtgtgc tcgaggtcga cggcgcggag gtgacggtgg taccgctcgg
    15181 cgcgacgccg ctggccgtcg cggtgtgggc gaccgagccg ttcaccgcgt cctgcgcggt
    15241 gatgacgtag cgggtcgggc ggacgcactc gacggtctgg ttgggctgca gcgtggtgat
    15301 gacacccgcg caggggttgg ccaccaggtc gtcgccggtg acgacgacgc cggtgagcgg
    15361 cacgttgccc gagttcgaca ccaagaaccg gtagtcgatc tcctcgccga cctcgcccac
    15421 ggtgtcgccg ttggtgtcga tcaggttcgc ggtgcggacc agctcgatcg cgggggcggc
    15481 ggcgaaggtc gggatgttgg tgacggtggg cgcggaggcg accagttcac cgtcgggggc
    15541 ggtcgcgctc gcggtgctgg tcgtgacgac ctgacccgcg gtgacgtcgg cggcgttgac
    15601 cacgtgcgcg ggcgcggagc aggtagtgct ctgccccagc gacagcgtgg tggacgcgca
    15661 ggtgacggta ccggcgccgt tgtgctgcac ggagaggttg aacagggtca cgttgccctg
    15721 gttgtgcgcc tctagcgcgt aggtgatgtt ctcgccgacg tcgccgacac cgttgccgtt
    15781 ggtgtcgttg aggctggcgg aggccagcag cgccacggag ggcgcggggg cggcggtagt
    15841 ggtgacggtc gtggccacgt tgttgccggt gttggcatcg ctgtcggtcg ggcctgtcgc
    15901 cacggaggcg ctattcacca gggggaaggt gaacggcgtc ggggtgttcg cgttgattcg
    15961 gaacgtcgcg gaggaacccg ccgcgagtgc gccgccaccg caagagacaa cattgcctga
    16021 aaccgcgcag cccgcggtag ggctagagac gccggtaacc gaatcgggca cggtgtcagt
    16081 aacagtgaaa gacgatgcag aaccgggacc gttatttcga acggtgaggg tccaggagat
    16141 cggggcaccc gcgttagcgg cctcgggggc gtaaacgctc aaagcgaggt cgacggtcgc
    16201 gcggggatca gcctcttggc cgctgggcgc gtcctccacg atcggtgctt cctcgatcgt
    16261 gggttcctcc tgcggctcac ccgagggcgc ctcgtcgacc ggggcggtct cgctcgggga
    16321 ttgctccgcg ggaggggttt gcgccggggg gtccactggg gactcctcgg tcgcgggggt
    16381 gggggacgcg ggatcggaga cctcggtcgc ggtggccgcc tcgcccgcga cctccacttg
    16441 ggccgggtcg accgggtccg ggtcggcgag cacgggacca cccgtggaca ccagggtcgc
    16501 cagcaccagc agcacgaccg cgactttcgc gcccgatctg cgggtcaatg ggggtaggaa
    16561 agacctgccc cccgcttctg gggacgactt gcgtttgagc atcccgcacc tcaccacatg
    16621 gtcggaccaa ccaggaagtt ccctgggtgg attcaaagac tagggccggt ggggcggcga
    16681 acaacgcggg tgaccactgt ccacccggaa gagtggccag tagtgatgag agtgcggcta
    16741 cttgtcaccg atctattcta aattcggccg ggcgagctaa cccgatttcc cgtccttgca
    16801 ccggatcgag cgagatcgcc actgtaacgc ttccatgatc agcgcgattg gatcactcgt
    16861 cccgctcggg cggggacccg tgctaccggc cggtatcggt cggcgggacc gcgaagtagg
    16921 cggtcagcgt gccctgctcg tcgtcgacgt cgaggtcgac ccgctcggcg atcctggcga
    16981 tggcccgcag cctgcgctcg ccgggctggt cgccgtgctg ggcgcgcgcg gtccaggtga
    17041 agtggtcgac ggcggtgagc acgacgacct cgcggtccca gagcaggctg acggtggtgt
    17101 cgcggccctc cctcggctgg tcgatggcgt cgctgagcgc ctcgtgggcg gccagcacga
    17161 cgtcctggcg caccggggtg ggcacgcgca ggccgtcgag ccagccccag acgcggcggc
    17221 gcagcggcgc caggtgttcg gcccgcgcgg gcacggtcgt gctgaacacg gccaagtcct
    17281 ggtgggtcgt catgccagag gactgcccac cgtcgccctg cgccacaccc gatggttcaa
    17341 ccaatcacat cggggctgca ctgatcgggt gagtggacag ggcgcgctgt caccgcgtga
    17401 gcgggcgaga cggtgtacgc acgctctagt cgcagacgac cgtgggttct cctacctggg
    17461 ctgggacgtt gacggcgttc cacgcggcct tcactgcgtt gtagtcagtg cagttgcctg
    17521 gagtaagaag ctgcgcggcc ttaagcgtcg cgatgcggta cttctggtag gtcatgccgg
    17581 acaccttgaa ctgcatcgcg gtgtagagga tccggatagc cctatcgacg ccgatgccgg
    17641 tgacagtcgt accctcgcag gtggggcttg gcgggaggcc gttggtaggg cgggatcctg
    17701 ccgctagaag cgcgaaccag tggttgccga cgcccgctgc ggagtacacc tcggcggtgg
    17761 ggacggcgct ggtgtagcag ttgataccac cggtggcggc tgggttcgac atgtcgcgcg
    17821 gggtgctcgg tcgttcgccg accaagaggt ctggcacgtc cccagctgtt tgaccggcga
    17881 accactcgtt ggccgtgccg aacgcgtccg cgatgaactc gccggtgccg ttgcgcgaca
    17941 ggccgcccgg agtggtctgg tcgatcaacc ggccgtactc acggccgatg aggtccagcg
    18001 agccgaccca ctggcccgcg gagttgcggc cgaccgagat ccgcccggcg acaacaccca
    18061 gtcccaggcg cgaatccccc acgcggaggc cgaagccggg gcggccgttg ccctcggcgc
    18121 cgttgcggcc caaccagcgc acggtcatcc gctggaagtt ctgcgccgcg tagtaggcgt
    18181 cgacgcaccc ggtctcgcgg tcagtcgggt cgccgttgcc ccagacgtcg tccggaccgc
    18241 tgaagaccac gccggtgacg gcgtccacgc agtccaagcc gatccaccgc gggtcgcgca
    18301 tcacgtaggt ggagccggac aacgtcgtca ccaccggcac cgggttctgg ttccacgcgc
    18361 cggtccccgt gcccgagggt tgcgctgctg acggtgtggc cgcgagcagg ctcaccactg
    18421 caccaatgac cagtccacgc gtgtggattg tccgtttccc cacgatgtcc cccaggttcg
    18481 ccgcctcggc tccagggtcg accggaatgg cttgcggcac aagagatccc ggccatgaac
    18541 agataaccac ccggaacgct cacgcgggtt ggcgaattcc caacagtgga ctcgaggtgg
    18601 gtcggcgggt catgatggtc tagacctttg ttccctgccg cagaggagac caccgatggg
    18661 gatccgtcgc gccgccaccg ccgtggtggc catgaccggg gcgctgctcg cctcgaccgt
    18721 gctcgtcgcc gcgccagcca tggcccacgg gtcgatgggc aacccggtca gccgcatcta
    18781 ccagtgcttc accgagggac cggagaaccc gaggtcggcc gcgtgcaagg cggccgtgca
    18841 ggtcggccag agctggccga tctacgactg ggacgaggtg aaccagccca acgccaacgg
    18901 caacagccgc cagatcatcc ccgacggcaa gctctgcagc gcgggccgcg acaagtacaa
    18961 gggcctggac ctcccccgcg ccgactggcc cgccaccacc ctccccacgg gcgcgtacac
    19021 gttcacctac aaggccacgg cgccgcaccc gggcaccttc gagctctacg tcaccaagca
    19081 gggctacgac cccaccaagc ccctcaagtg gtccgacctc gaggccaccc cgttctacaa
    19141 gcaactcaac cccccgcgcg ccagcggctc ctaccagctc aaggccacca tcccgtccgg
    19201 ccgcaccggc cgccacctca tcttctccat ctggcaacgc cacaagcccg acagcggcga
    19261 agccttctac agctgctccg acgtcctctt caactaaccc acccaggccg cgggacaccg
    19321 tcccacccgc ggtcaggtca gtcgaatatc gagatcccgc cgcgccactc gatgccggcg
    19381 ggtcggtcgc ccgtggtgat gaactccatg atggcggcgt ataccgcgtc gatgggtact
    19441 cctgtgtgcg gtcggaccgc gtaggggtga agacccgcgg ccgcatagtc ggtccagtcc
    19501 ggattagcgc cggacgcagg tacccacacg tcctgaccct gccgccattc caggacgccg
    19561 acagagttgt tcacacccgc ggtcaagatg ggctgctcgt cattgggcga gctctgccgg
    19621 gtccgcgtga actcccacag ccacggcacg tcaacccccg cggagttcag cgcacacacc
    19681 tcggccacga cgtccacacc ggcgggaatc tcgtcgatcg cgatcgcgcc gcggtgggtg
    19741 atcggttcat cgggcttggt cacctcgtcg cctctccgtg gtaggtccgc ttgaaggggg
    19801 gcccgcgggc gtcggtcccc aggaccgtga gctcgcccgc gaatcgtttc gaagtctcca
    19861 tctccggcgg cgacatctaa cacaaggcgc tgatgtaagc atctggcgcg cctctcccac
    19921 gtgcggaacc atcaggctcg tgcggtggtt gaccgagtgc tcagtggaca cagtgcggga
    19981 cgcgctgcgg gttgtcgcgc ccgggttggc tgagctcccg atcacgctgc ccgatctggt
    20041 ggggcgggac gagccgctgt ggatggcgtc gagtgctgct gtgggcgagg agttcgtggc
    20101 gaaggtggcg tggtcggctc cggcggcgcg gcgattggct catgagatcg gtgtgttgac
    20161 ggcgttgtcg gtgccgttca tgcccgaggt cgtcgcgagt agcaccgagc cggtgttgct
    20221 ggtcaccagg cggatgccgg gaaagtcgct gttcgctgtg gtggactcca tcgaccgtga
    20281 tcacgccggc aggcagctgg cgcagttcct ggtggcactg cacgacccga gtacgcgcgc
    20341 ggccgtcgag cgagcactcg gcccgctacc cgccccacga gcggaggcct cgaccgacga
    20401 gatccgtgcc cgtctcggcc gatgggtccg ccccgaccaa cacgccgccg tcaccacctg
    20461 gtgtgcctgg gccgacgagg ttctggccga accgcgccca tccgtactgg tgcacggcga
    20521 cctccacggc gacaaccagg tctggaacgg cgaccgactg tccctcgtgg tcgacttcga
    20581 aaccacgtcc gccgccgaac cggaatacga cctgcgcgcc ttccccagca ccggccccga
    20641 ctgcgagctg ctgaccgcca caacccagca ctacgaacac ctcagcggcc ggtccctctc
    20701 cctcgaccgc atcatggcct ggcacctccg caccaccctg gacgacctcc tttggcgcag
    20761 cgaagccaga gttcccctcc ccggccacca ctcccccacc acctggatca acgacctcac
    20821 cacccggttc gccaagctcc agatcggccc ttgagcaagc gacgagtagg tgcaggtccg
    20881 cgcgttactc gacgttggcg atcacccggg tcgcgtacag gtcgatcgac atcatcgtcg
    20941 tgtcgaccgt gcagccgcgt ctcccacccg gagcggtcca agcccagagg ccgatcagga
    21001 gcgcgtgtcc gtaggtcggg tcgacgatga tcggcaggtc tggttcgacc tggatcacct
    21061 cggcctcgac gaactccagc gacacggccc gaccctcgat ggagaagtcg accaccaccg
    21121 acagcgcttt ggcaccggcg acgaaccgga taccgaccac cgcgccatcg ttgcggaggt
    21181 cgatctcccc cagttcgtcg agcacgacgt cgatctggct cgtctcgccg aagggctgga
    21241 taccgatgaa gtccacgtgg acagtctcta gttcctcagg tgccgccgat agccgcagtg
    21301 cggatcgcgc cacccaacca ttggcaccgc gaccggggga tcgcgcaggt tcttcccctc
    21361 ggtgaacttg tgcgcgatct ctattggggg cggtggctac ctggtgtttg aagcgcaggg
    21421 cacctcagct gacgcacagt gctgtggcct tggccgtgtg gtagtacttc ggcgggaccc
    21481 acccggacgc cacctcggtc accacccagt cgacgcagtc gacaccagcc tccagcacct
    21541 cggcccgagc ccgccgctgg gcattcgcct tggcgatggc aggcgcctga ccgaccgcga
    21601 ccaccgtcgc ggaccggggc accgtgtagt ccgcggccga tgccggagtc tggaccatcc
    21661 cggtcagcag aacagcgagc acgagcacct tcgcgagtgt ggccatcaca ccatgctcgc
    21721 aggacatgat cgaccaggca atcgaccgat cggaccgcga tgcacgttcc ttggtcatgc
    21781 ccctcggttc gggtcaggcc gtagctcggg tgtactggtc ggcgaaggcg cacagcttgt
    21841 ccatgagttg gtggtgcgct ccgatgtaga cctcacgcgg ggcgttcttg tccgaccagc
    21901 gctgccacga tccgctgacc aggaactgcc ccgcataccg ggtcaccagg cgcgagtcca
    21961 ggtgcagcaa cgcgcccatc gcccaggtct ggtcgtagta cctgtcgacc gcca
//
