LOCUS       NZ_JAMTCR010000003     25055 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Actinokineospora globicatena strain DSM 44256
            LV79DRAFT_scaffold00002.2, whole genome shotgun sequence.
ACCESSION   NZ_JAMTCR010000003
VERSION     NZ_JAMTCR010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinokineospora globicatena
  ORGANISM  Actinokineospora globicatena
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Actinokineospora.
REFERENCE   1  (bases 1 to 1257332)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1257332)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUN-2022) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: AllPaths v. r46652
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 261.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024171945.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 06:43:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,731
            CDSs (total)                      :: 6,666
            Genes (coding)                    :: 6,609
            CDSs (with protein)               :: 6,609
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 8 of 57
            Pseudo Genes (incomplete)         :: 49 of 57
            Pseudo Genes (internal stop)      :: 2 of 57
            Pseudo Genes (multiple problems)  :: 1 of 57
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:43:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 433719
            Orig. end                         :: 458774
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAMTCR010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25055
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="3"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25055
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25055
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15055](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15055)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            46..606
                     /locus_tag="LV79_RS15315"
                     /old_locus_tag="LV79_003017"
     CDS             46..606
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03086.1"
                     /locus_tag="LV79_RS15315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003017"
                     /product="TIGR03086 family metal-binding protein"
                     /protein_id="WP_253836983.1"
                     /transl_table=11
                     /translation="MLNAARAEFQRRLVHLTPDNSGAATPCPEWTALDLVNHVVAGDRM
                     AADLLDGATAEAAVATLRAQWLGDDPLAAFTSAGTELDRAIAVPGALDAVVPHPVGPVP
                     GHQAVTFRVTEHLVHAWDLARALDLDDTLDPALVEHTWQTLHGMAAVIGTLGIFGTGPS
                     GTLDETSPLQDRLLDLLGRRPGA"
     gene            775..2199
                     /gene="rox"
                     /locus_tag="LV79_RS15320"
                     /old_locus_tag="LV79_003018"
     CDS             775..2199
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene="rox"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020673444.1"
                     /locus_tag="LV79_RS15320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003018"
                     /product="rifampin monooxygenase"
                     /protein_id="WP_253836985.1"
                     /transl_table=11
                     /translation="MIDVIIAGAGPTGLMLAAELRLHGVRVVVLDREPAPTEHVRALGL
                     HVRSIELMDQRGLLDRFLAEGTQYPLRGFFAGIAKPAPERLDTAHNYILGIPQPTVERL
                     LTEHATGLGAEIQRGRELVGLSQDDTGVDVDLADGARLRARWLVGCDGGRSTVRKLLGV
                     DFPGQAATVEWLLGEVEVSLSTEEMTAAAALAPESYIRFGPSPNTDGLYRFVVRTDRAI
                     EDRATTPTFDDLTQRLRDLTGTDLGIHSPRWVTRFGDATRQAERYRVNRVFLAGDAAHV
                     HPPMGGQGLNLGIQDAANLGWKLAATVNGWAPADLLDTYESERHPVAADVLTNTRAQAH
                     LLSTEPGAQAVRALITELMDIEEVNRHLIAKIVAIDIRYPLGDGHPLQGRRLRDIALKQ
                     GRLYSLTHTARGLLLDQTGTLSPTGWSDRVDHVVDISEELDTPAVLLRPDGHVAWTGDS
                     QEDLTTHLSRWFGPAT"
     misc_feature    2358..2374
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.62"
                     /tool="antismash"
     gene            2366..3088
                     /locus_tag="LV79_RS15325"
                     /old_locus_tag="LV79_003019"
     CDS             2366..3088
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (39-138). E-value: 1.1e-11. Score:
                     35.4. Matches aSDomain: nrpspksdomains_LV79_RS15325_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020420574.1"
                     /locus_tag="LV79_RS15325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003019"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_253836987.1"
                     /transl_table=11
                     /translation="MGCVSDYDGFAEAYAAGNETSLENAYYERPATLALAGDVAGRRIL
                     DAGCGAGPLSAELLSRGADVSGFDQSAEMLALARRRLGSDVDLRVADLASPLPYADDTF
                     DDVIASLVLHYLQDWAPPLAELHRILKPGGRLIASVNHPTADYCLERLSGRRPNYFTTY
                     SSPAEWTTGGQTIKVTFWNRPLHAMTDAFTTAGFRLTTLSEPQPLLTAAPLYPDGYPLL
                     TTAPSFLFFVLHAASPTG"
     aSDomain        2483..2779
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LV79_RS15325_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.10E-11"
                     /label="LV79_RS15325_oMT.1"
                     /locus_tag="LV79_RS15325"
                     /protein_end="138"
                     /protein_start="39"
                     /score="35.4"
                     /tool="antismash"
                     /translation="AGRRILDAGCGAGPLSAELLSRGADVSGFDQSAEMLALARRRLGS
                     DVDLRVADLASPLPYADDTFDDVIASLVLHYLQDWAPPLAELHRILKPGGRLIA"
     gene            3177..3308
                     /locus_tag="LV79_RS33900"
                     /old_locus_tag="LV79_003020"
     CDS             3177..3308
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS33900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_003020"
                     /product="hypothetical protein"
                     /protein_id="WP_285470135.1"
                     /transl_table=11
                     /translation="MGLKIASNGQFGAIVAIDTLHTLAQRFATFTIRLVPPPALSFA"
     gene            complement(3295..>3468)
                     /gene="cutA"
                     /locus_tag="LV79_RS34795"
                     /pseudo=""
     CDS             complement(3295..>3468)
                     /GO_process="GO:0010038 - response to metal ion [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cutA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015077.5"
                     /locus_tag="LV79_RS34795"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="divalent cation tolerance protein CutA"
                     /pseudo=""
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="WQILLKTTSGRFADLRDHLVSEHEWDNPEVTATPVTEGSAVYFDW
                     LTRAVSPDVTQS"
     gene            3923..4195
                     /locus_tag="LV79_RS15330"
     CDS             3923..4195
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS15330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_253836989.1"
                     /transl_table=11
                     /translation="MRRLLLAVCLATAGVAGALTPAAAAPPPVIHHGPYPTVTECETQA
                     QAWRDSETGRAAWASECQHRSTSQLPTGWYFRTLYAPELPIPNLP"
     misc_feature    4840..4854
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.24"
                     /tool="antismash"
     misc_feature    complement(4968..4988)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.14"
                     /tool="antismash"
     gene            5140..8082
                     /locus_tag="LV79_RS15335"
                     /old_locus_tag="LV79_003021"
     CDS             5140..8082
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044870.2"
                     /locus_tag="LV79_RS15335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003021"
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="WP_253836996.1"
                     /transl_table=11
                     /translation="MGIGLSRVPRRRGGWRRGVALAVSASLASVGLLAVGAQPAAAAVV
                     THPFAYVANSGGNTVTAYDSVTSAVVSTIVVGTTPLDLVATPDGARVYVTKNSGGVSVI
                     DTATAAVVASIGVGSQPNGIAITPDGARVVVANSGSNTVSLIATATNTVTATVPVGSHP
                     TGVAISPSGATAYVTNDASGTVSVVDLAAAAVIATINLGLHQPIGVAATPDGSTVYVAQ
                     YGNGTVAVIDTATNTVTGTIAVGAIPSGVAVTPDGARAYVSNIGPDTVSVIDTATNTVT
                     ATVSVGSNPSRVAVSGDGSTVYATNNGASSVSRIDAATNTVTTTFGVGSGPYGVTTALV
                     SQPRVTALSPTSGPLTGGTSVTVTGTDLAAATSVRFGATSASFTVVNNTTVIATAPAHA
                     AGTVDVTVATPTGTSTITAADQYTYLDPTPTITAINPATGPAAGGTLVTITGTYFTGAT
                     AVTFGSTAAVSFTVNSDTSITATAPTGTAGTVDVTVTTPAGVSATTTADDYTYVAAPTV
                     TAVSPNAGPLGGGGTVTISGTALTGATAVHFGATTASFTVTSDTSITATAPPGSAGTVD
                     VTVTTIGGTSTTSSADQYTYLAAPVVTGVSPTSGPIAGGTNVTITGTGFTGATAVRFGT
                     TAATSFTVTNSTSIAAIAPAHVAGTVDVTVTTVGGTSASTTADRYTYLDADLSVTVADS
                     TDPVALGGDPYTYTVTAANAGPTNATGVTLSTTLTGAVTINLVTASQGTCSISSLTVSC
                     SVGSVAAAGSANVAISVTPSATGTVTASSSVSATEPDSVPGNNTDTESTTVNNALGCTI
                     VGTSGNDVLNGGNGNDVICGLGGDDVINGGNNDDTIYAGAGDDVTDGGNGNDIVHGGDG
                     DDVVGGGNGADTIYGDAGNDTNYGETFWGSLLYLFDNGNDVIYGGPGNDDLDGQNGNDT
                     IVDHDGTDIMSGSNGNDTIDVLDGTGGDTANGGLGSDTCSADTGDTKTSC"
     gene            8304..8864
                     /locus_tag="LV79_RS15340"
                     /old_locus_tag="LV79_003022"
     CDS             8304..8864
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS15340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_003022"
                     /product="hypothetical protein"
                     /protein_id="WP_253836998.1"
                     /transl_table=11
                     /translation="MTSSTPGSAAPSPRRDIRTRWPVAPAALVQAVLAIFVLVTPASAA
                     SVDVESLGTFSRSFSPPVTLTPQTVTVASTFDYATCPVGSPSTGTGSLSLGCVPVTVGP
                     AAAETITWQDTTGGTSTIDWASPVITGQTVVYTGTVSAGRHAGDTATKVTSGTSYLGSV
                     IGCSFGTPISSTTGLVDSFLLTH"
     misc_feature    8965..8979
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.37"
                     /tool="antismash"
     misc_feature    complement(9069..9083)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            9224..9997
                     /locus_tag="LV79_RS15345"
                     /old_locus_tag="LV79_003023"
     CDS             9224..9997
                     /EC_number="3.4.23.43"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013632.5"
                     /locus_tag="LV79_RS15345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003023"
                     /product="prepilin peptidase"
                     /protein_id="WP_253837000.1"
                     /transl_table=11
                     /translation="MASKRVDEHPVPIDVDVLDRLVRLTTTHPHQVVHHRGRDTGLDLR
                     RQQCVAAPQLAVGVGVRGLLHWHRSKRAALGLGYRRSTDRVICDDPVVELRGHSLTQRL
                     PVGPALAAYSALAALLAPLVVIDARDQRLPTKPMIVAAATTTIMFIAFAAVDHEPGPLL
                     RALASSGTCVLLLVITYLITSGFIGGGDIRLAALLVLALGWTGWSAAARSIMIGLIIGA
                     MYSQYLRLRLRLGPLAHIPLGPALALGALSSILID"
     gene            complement(10001..10798)
                     /locus_tag="LV79_RS15350"
                     /old_locus_tag="LV79_003024"
     CDS             complement(10001..10798)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="LV79_RS15350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003024"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_253837002.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.8e-35, bitscore:
                     117.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDPEWLQISVEFTDYSKAELITADRLLPVMERAASWWFIRKAPCW
                     RLRYLPTDPTQANELRKTVSESLNSLHSAGEITDWVETIYEPEIHAFGGTNAMAAAHRL
                     FHHDSQQILSRPNELNHRREHSILLCSELLRAAGQDWYEQGDVWARVASNRPGQSPAPD
                     EQRTLATDLQRLMAVDMGRDSALVRPGGQLAHLAGWVESFRVAGESLIVFARRGQLTRG
                     LRATLAHHVIFHWNRLGLSYETQSRLAAAAREAVFGTHDQERR"
     gene            complement(10830..12029)
                     /locus_tag="LV79_RS15355"
                     /old_locus_tag="LV79_003025"
     CDS             complement(10830..12029)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007024582.1"
                     /locus_tag="LV79_RS15355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003025"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_253837004.1"
                     /sec_met_domain="LANC_like (E-value: 1.4e-44, bitscore:
                     148.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEIAVELGEPGSPATHVGNHTPRPQSLAGGSAGIALLHIERAF
                     TQPEHRAVAHTWLSTAACDDLDGSPSSCLFYGVPALAFLTHAAAEATGGYQHAQADLAT
                     ATRQVTRARLTAAHARIDRGERPALAEFDLIRGLTGLGAYLLLRSPDHRITRDVLIYLV
                     RLTESLPGDDLPGWWTEHGPTGQAPTDYPGGHGNFGMAHGITGPLTLLALALRQGVAVP
                     GHAEAIARICAWLDAWQQPHDAGSWWPRTITLAEARTGCCDQPGPAQPSWCYGTPGIVR
                     ALQVAALATHDTTRQHTAEAALLNCLNDPDQLARIIDPSLCHGAAGLLYTTWRVARDAA
                     TDELNNHLPMLATLLTDQLVTSQRNGELLEGSTGAALAIHAVVTDTRPSSQWDACLLLS
                     "
     misc_feature    complement(11385..11387)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    12014..12028
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     gene            complement(12035..15055)
                     /locus_tag="LV79_RS15360"
                     /old_locus_tag="LV79_003026"
     CDS             complement(12035..15055)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="LV79_RS15360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003026"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_253837006.1"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 3.1e-19,
                     bitscore: 65.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.9e-116,
                     bitscore: 385.7, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1e-30, bitscore:
                     103.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKVFTVVDAAMLRMATQPVTAGEWPDVAGDVPQWRGWLARAWAD
                     EQFANAVGAASPDLARRVAAVCAGKEVRPRQVRGAVLSLLRYRLRASSRATPFGLFAGV
                     APVRFGPTTLVHVGDQHHLTERVDAVWLSSLVSELERCDELITRLPVVLNNTAVERDGR
                     LIINLRQHPNPDAARTDPAEVTVRYTRAIALVVRNARTPILMSDLVDRLSNEFPDVPPT
                     TIASMVATLVEQRVLLTGLRPPMTSVDPVRHVLTALAQVDADQVPATSGIVARLHERPA
                     VVADGGTDMRVDAQVVLPETVAREVEHAANVLARLTPHPFGAPRWLDFHARFLERYGIG
                     AAVPLLELADPDLGLGYPAGYRDSLLDVPAPATNDRDVALLRLAQTAAMNRRVEVILDE
                     SAITELEAPNFGQAQLFAHAELAVRLHAPSPAALGRGDFSLVVTGAFRAAGTTAGRFLD
                     MLDESDRDRMVRAYTDLPSVNADGQRVQVSCPPLYTETENVSRHPQVLPNLIPIGEYRP
                     AFEREFAPEDLVVIGDAHRFTLWSRSTARPLEPEVFSAVEFTNFSHPLLRLVCELTTGR
                     AATWGPFSWGIATQLPFLPRLTYRRTVLAPARWTLNAADLPAKSAPWAEWNAAIDAWRE
                     SAMAPAMIYLGGNDQRLRLNLDEAAHLYLLRAQLDRHGHATMQEAPRDDAFGWIGEHAH
                     EIIVPLASTKPRAWPALPPRATPLHATTAHDGHLPGAGEWLYCKLYGHPDRHSAVLASY
                     LTELLPTLDETVQWWFLPYRDPDNHLRLRIRLTDPAQFGPVAAELGAWAMRLRQRGLIA
                     TMQMDTYLPETGRFGHGPTMAAAEDVFAADSVVALAQRTHLTSPGAVDDRALVTASLVD
                     LATGFTGDQAAAATWLIEHITTGSASAHDRRVYDQALHLSDPRAEQAAIRNLPGGEQIA
                     TAWTARRTAVANYRAALTQAGGPPPNAVLGSLLHLHSVRTLGISPDAERTSHRLARAAA
                     LSQTSYRKGRRCETSTH"
     aSDomain        complement(14324..14605)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_LV79_RS15360_Lanthipeptide_LanB_RRE.1
                     "
                     /evalue="8.20E-21"
                     /identifier="RREFam001.1"
                     /label="LV79_RS15360"
                     /locus_tag="LV79_RS15360"
                     /protein_end="244"
                     /protein_start="150"
                     /score="65.5"
                     /tool="antismash"
                     /translation="VVLNNTAVERDGRLIINLRQHPNPDAARTDPAEVTVRYTRAIALV
                     VRNARTPILMSDLVDRLSNEFPDVPPTTIASMVATLVEQRVLLTGLRPP"
     misc_feature    complement(15049..15066)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.08"
                     /tool="antismash"
     gene            complement(15133..15303)
                     /locus_tag="LV79_RS15365"
                     /old_locus_tag="LV79_003027"
     CDS             complement(15133..15303)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04363.1"
                     /locus_tag="LV79_RS15365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003027"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_253837008.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 2e-18, bitscore:
                     62.1, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNSTQSAPVQAVASGGEFDLDLTIVSSGPVVPDLMRSTDDNCGA
                     TCQSACSNSTC"
     CDS_motif       complement(15202..15303)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MLNSTQSAPVQAVASGGEFDLDLTIVSSGPVVPD"
                     /locus_tag="LV79_RS15365_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15133..15201)
                     /prepeptide="core"
                     /locus_tag="LV79_RS15365_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="0.60"
                     /molecular_weight="2142.3"
                     /monoisotopic_mass="2140.8"
                     /core_sequence="LMRSTDDNCGATCQSACSNSTC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLNSTQSAPVQAVASGGEFDLDLTIVSSGPVVPD"
                     /leader_location="[15201:15303](-)"
                     /alternative_weights="2160.3"
                     /alternative_weights="2178.4"
                     /alternative_weights="2196.4"
     misc_feature    complement(15349..15364)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.4"
                     /tool="antismash"
     gene            complement(15361..16599)
                     /gene="fxlM"
                     /locus_tag="LV79_RS15370"
                     /old_locus_tag="LV79_003028"
     CDS             complement(15361..16599)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016698391.1"
                     /locus_tag="LV79_RS15370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003028"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_253837010.1"
                     /sec_met_domain="PCMT (E-value: 2e-42, bitscore: 141.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTLRDNDTTTPDAAALRTAMVEQLRSEGELRTDPVIRAFATVPR
                     ELFAPEAPLEQVYDRDDVVITKRDENGLAVSSVSAPRIQASMLEQAEVRPGMRVLEIGS
                     GGYNAALIAELVGPDGEVTTVDIDQFVVDRARACLAEAGYDRVRVLLVDAEGGVPEHAP
                     FDRIIVTAGAWDIPPAWIDQLAPDGVLVVPLRMRGLTRSVAFVREQGRLVSRGYELCGF
                     VPIQGSGANAERLVLLHGEDVALRLDGDQAADADALSAALTSERVVRPSGVEVGGFEPF
                     DELDLYLATELDGFGLLVATPAAIEAGLAERSARMGAKTALDGVSFAYRASQATTKERT
                     AFEFVVYGHGPDADAVAFRYVELIREWDRTHRGGPGARIEVHPTGTPDTEIGEGRLIDK
                     KHTRVLISWPTSS"
     gene            16897..17766
                     /locus_tag="LV79_RS15375"
                     /old_locus_tag="LV79_003029"
     CDS             16897..17766
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.4"
                     /locus_tag="LV79_RS15375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003029"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_253837012.1"
                     /transl_table=11
                     /translation="MVASASSSPTALKWWFAVEMRRLREKADLTREEAAAAIKGSVQGV
                     GHIETMKSLPKPLELDKLLEIYGVPERAEFFQDLRVRAKRGKDWWIGFSGSVPSHLNLF
                     LGLESSAIQIESWDANLVPGLFQTPEYAHATIKAGRPELPAAEVDRLVELRMARQRQVL
                     DRDNPPLVWSVIAESALSWQVGGSDVVRGQLEHLADLTTRSYVEVQVLPLAAGAHTGTE
                     GTFTLLSAPPELENYAGCAYVEDRIKGHYYEEVEQITTYRNALTRLRVLAINPTESPEY
                     IHRLIKDL"
     gene            17772..17996
                     /locus_tag="LV79_RS15380"
                     /old_locus_tag="LV79_003030"
     CDS             17772..17996
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020636178.1"
                     /locus_tag="LV79_RS15380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003030"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_253837020.1"
                     /transl_table=11
                     /translation="MRYEDAVTALAAAANWHKSTYSGGQNGGCVEVGSVPGLVGVRDTK
                     LGANSPTLAFSSVRWAAFTDSVRCHQSDL"
     gene            18484..20313
                     /locus_tag="LV79_RS15385"
                     /old_locus_tag="LV79_003031"
     CDS             18484..20313
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024965.5"
                     /locus_tag="LV79_RS15385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003031"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_253837022.1"
                     /transl_table=11
                     /translation="MTGNDVGASSPQADEEFTADWQSCSATPDCRGVAIGDSDRCLRHV
                     DNEGRARALQAANASNRWDCLRGVQIDNELLQQIRGVAGTDRRGREEFQSLDATGAVFT
                     DYADWSGVAFTGSMVSFADATFAAGASFQGSSFPNDALFGATTFTRGADFSRAEFAGRA
                     FFKSADFDDDARFDAATFSGPLVLNGTKVQKDARFAYGKFEASVYLQLVEVGGNLDFSS
                     GRFEDGLTIEHCAVKGRFDLTKGHVAGPSAWADLTAIQMVNLSSAVFNDPLEAEITTRH
                     LAAVATNWRADVRLRLAGANAVLSHATFGEPSTISRRRNAIDFQPHWADKPDLMTCEPR
                     IVSLIGANVDKLTIADVSIAACCLTEAHNLDKLRLEGADLLARTPANRLWTSRLTISEE
                     HEWRAKHHHGRRQRDWFGAPTQPHPWENTDFSNPHPPTSPERIAETYRSLRKSREDAKD
                     EPGAADFYYGEMEMRRAALKVRLDAKERVATQRQTRRSARVEYGLLTLYWLVSGYGLRA
                     WRALAIFGVLVLLASFYFAWCGIPAGLPAAGAAYISRWGQGLLIALESATSLIRAPSKP
                     VTTAGEWAVLVLRYLGPLLLALAALAVRARVKR"
     gene            complement(20419..21297)
                     /locus_tag="LV79_RS15390"
                     /old_locus_tag="LV79_003032"
     CDS             complement(20419..21297)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101038.1"
                     /locus_tag="LV79_RS15390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003032"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_253837024.1"
                     /transl_table=11
                     /translation="MPIPVPDALAAYYAKQSPEHLPWLRALPTLADTMLERWSLKVDGP
                     ARHGMVALVIPVVRPDRTPAVLKLQPRDEENDGEPLALRHWAGNAAVHLLDHDEPTGAM
                     LLERLDASRPLSALPASEGIAVIADLLSHLHVPAPPGIRTLTDIATAMLAERPLLNRLI
                     NPTERTLAITCADATAAALSEPGNRLLHWDLHYDNVLASSRTPWLAIDPKPISGHPAFD
                     LMPALDNAYLTPTALLHRFDLLTESLSLDRPTAVAWTLARTLQNTLWSLHDGETTLDPI
                     QAAIASTLLAR"
     gene            complement(21357..23114)
                     /locus_tag="LV79_RS15395"
                     /old_locus_tag="LV79_003033"
     CDS             complement(21357..23114)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801599.1"
                     /locus_tag="LV79_RS15395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003033"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_253837026.1"
                     /transl_table=11
                     /translation="MSVPKSGRLRVLWSFARPHRARLALGLVLALAGSGVGLATPLATK
                     WVLDSLGADGGLRGPIVLMAVLLVVGAVMWTWQSVVLGTLGERIVLAARQGMVDRFFRA
                     TVPAISTRAPGELVTRVTSDTLLLRDAAAASVIGLINGVVMLVGTLVLMAALDLVLFLT
                     TVASVIAIAILFGLLMPAIAVAKEKAQAHVGALGGTLEGALRAVRTVKASRAEQRQTAT
                     IITDARGAAEQGIRAIRREAIAWAISWSGIQLAIILILGIGAWRVSDGDMAVSTLIAFL
                     LYSFGLMGPVTTLSQNVTALQNGIAAAGRIREVDDLPVETSGVSTNATVRTTGPVLELR
                     GITAAYGPDSPPAVRGIDLDVPRVGHTAIVGPSGAGKTTLFSLILRFLEPQEGSLLVNG
                     VPYRDLTHADIRAHLAYVEQETPVVPGTIRDNLLFSHPDATDDQLQSALAAVRLDTLAD
                     TLPEGLDTPLSGTSVSGGQRQRIALARAVLTDPDVLLLDEATAQVDGLTEAALHDVIRA
                     HAFHAAVVTIAHRLSTVVDADTIIVMAEGRIRARGTHAELLATDSLYRDLVESLRIPDS
                     VAKVGSMGH"
     gene            23193..23759
                     /locus_tag="LV79_RS15400"
                     /old_locus_tag="LV79_003034"
     CDS             23193..23759
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007035439.1"
                     /locus_tag="LV79_RS15400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003034"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_253837028.1"
                     /transl_table=11
                     /translation="MDLRTAADTGTKARTRRAILDAAVTVLTADPAASLGDIAAAAGVG
                     RTTVHRYFPERADLTTALQQMGWEHVVQATRRARLTEGTGADGLDRLCQEYFELGNVLM
                     LVFNYSAPDGDVTWDCDPDSQSVLDLITRGHRDGSIDSTLTGPWIRDILWALLYAAWQQ
                     SRTGVASRHQALDSCLRALHKVVAP"
     gene            23792..24502
                     /locus_tag="LV79_RS15405"
                     /old_locus_tag="LV79_003035"
     CDS             23792..24502
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016700738.1"
                     /locus_tag="LV79_RS15405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003035"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_253837030.1"
                     /transl_table=11
                     /translation="MAVYDTFDAPRDDLDAYVALVAELDARRVLDLGCGTGNLGVRLAE
                     RGIDVIGVDPAEASLAVARGREERVRWVHGDVGSAAGLDVDLVVMTGNVAQVFLTDAEW
                     TEVLAGCRAATRPGGYLVFETRRPQRRAWEEWDGQVVLDVPGIGAVSQRREVTEVRLPL
                     VSFRSTYRFPDGAVISSSTTLRFRDLDEISRDLAAHGYRVLDVREAPDRPGKEFVFVAQ
                     ASALVMNTLLGSST"
     gene            complement(24454..24921)
                     /locus_tag="LV79_RS15410"
                     /old_locus_tag="LV79_003036"
     CDS             complement(24454..24921)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018331223.1"
                     /locus_tag="LV79_RS15410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_003036"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_253837032.1"
                     /transl_table=11
                     /translation="MGELRVVVDDLSGAEVARFLEEHVEQLRAVTPPGSSHALDLEGLR
                     KPEVTFWAVRDGDVLAGCGALKELAPGHGEVKSMRTAGEYRKRGVASLVLRHIVGVATE
                     RGYERLSLETGSFEFFAPARALYAKYGFTFCGPFPPYVEDPNSVFMTKALA"
ORIGIN
        1 ggcgcaccga ggtctgttgg cccatcaccc gctaggagaa cccccgtgct caacgccgcc
       61 cgcgccgagt tccagcgccg cctcgtccac ctcactcccg acaactccgg ggccgccaca
      121 ccctgtccgg agtggaccgc gctcgacctg gtcaaccacg tcgtcgccgg agaccggatg
      181 gccgccgacc tgctcgacgg cgccaccgcc gaagccgccg tcgccacgtt gcgcgcccag
      241 tggctgggcg acgacccgct cgccgcgttc accagtgcgg gcaccgaact cgaccgggcc
      301 atcgcggtcc ccggagcgct cgacgccgtc gtgccgcacc ccgtcggacc cgtgcccggg
      361 caccaggcgg tgaccttccg cgtcaccgag cacctcgtgc acgcctggga cctcgcccgc
      421 gcgctcgacc tcgacgacac cctcgacccg gcactggtcg aacacacctg gcagaccctg
      481 cacggcatgg cggcggtgat cggcacgctc ggcatcttcg gcaccggacc cagcggcacc
      541 ctggacgaga ccagcccgct gcaggaccgg ctactcgacc tgctggggcg ccgaccgggg
      601 gcatgaggaa gggcaagggg aacgcactat ttccctcccc cttcaactta taacgcacag
      661 gggggcttgc ggcaagaccc cggtggtgcc ccagaatctg gcggccgacg cgagaacctg
      721 cggaaacgac gcgggtgtgt tctcgtcgga catcgcacaa cacgggggtt agccttgata
      781 gacgtgatca tcgccggcgc cggaccgacc ggtctgatgc tggccgcgga actgcggctg
      841 cacggcgtgc gggtcgtggt gctcgaccgc gagcccgcgc ccaccgagca cgtccgcgcg
      901 ctcggcctgc acgtgcgcag catcgaactg atggaccagc gcggcctgct cgaccggttc
      961 ctcgccgagg gcacccagta cccgctgcgg gggttcttcg ccgggatcgc caagcccgcg
     1021 ccggaacggc tcgacaccgc ccacaactac atcctgggca tcccacaacc gaccgtcgaa
     1081 cggctgctca ccgaacacgc caccggcttg ggcgccgaga tccagcgcgg ccgcgaactc
     1141 gtcgggctga gccaggacga caccggggtt gacgtcgacc tcgccgacgg agcccgactg
     1201 cgcgcccggt ggctggtcgg gtgcgacggc gggcgcagca cggtccgcaa gctgctcggg
     1261 gtcgacttcc ccggtcaggc cgcgacggtg gagtggttgc tgggggaggt ggaggtcagc
     1321 ctgagcacgg aggagatgac cgccgcggcc gcgctggcgc ccgagagcta catccggttc
     1381 gggccctcac ccaacaccga cgggctctac cggttcgtcg tgcgcaccga ccgggccatc
     1441 gaggaccgcg ccaccacccc gaccttcgac gacctcaccc agcgcctacg cgacctcacc
     1501 ggcaccgacc tcggcatcca cagcccccgc tgggtcaccc gtttcggcga cgccacccgc
     1561 caagccgagc gctaccgcgt caaccgggtg ttcctcgcgg gcgacgccgc ccacgtccac
     1621 cccccgatgg gcggccaggg cctcaacctc ggcatccagg acgccgccaa cctcggctgg
     1681 aaactcgccg ccacggtcaa cggctgggcc ccggcggacc tgctcgacac ctacgagtcc
     1741 gaacgccacc ccgtcgccgc cgacgtcctc accaacaccc gcgcccaagc ccacctgctg
     1801 tccaccgaac ccggcgccca ggccgtccgc gccctgatca ccgaactcat ggacatcgag
     1861 gaggtcaacc gccacctcat cgccaagatc gtcgccatcg acatccgcta ccccctcggc
     1921 gacggccacc ccctccaggg ccgccgccta cgcgacatcg ccctcaagca aggccgcctc
     1981 tactccctca cccacaccgc ccgaggcctc ctcctcgacc aaaccggcac cctctccccc
     2041 acaggctggt ccgaccgcgt cgaccacgtc gtcgacatca gcgaagaact agacaccccc
     2101 gcagtcctcc tccgccccga cggccacgtg gcctggaccg gcgactccca agaagacctc
     2161 accacccacc tctcccgctg gttcggcccc gccacctaac ccctttcccc gcgcggtggc
     2221 ccacccccac cgcgcggggg cccgcgtgcg cccagagccc gtctcgtatc acgccatggc
     2281 gccccgactc acctcgacga cctcaaccac tggcggtacg tcacccgttg gagggggcgg
     2341 gggcatcgcg tgcgcctatg ccacgatggg gtgcgtgtcc gactacgacg gcttcgccga
     2401 ggcatacgcg gcaggcaacg agaccagcct cgagaacgcc tactacgaac gtcccgcgac
     2461 cctggccctc gccggggatg tagcgggcag gcgaatcctc gacgccgggt gcggcgctgg
     2521 cccactgtct gcggaactgc tctcccgagg cgccgatgtg tccgggttcg accaaagcgc
     2581 cgagatgctg gcactcgccc gccgccgcct cggatccgat gtggacctac gcgtcgccga
     2641 cctcgcctca ccgttgcctt acgccgacga caccttcgac gacgtcatcg cctccctagt
     2701 gctgcactac ctccaagact gggccccacc cctggccgaa ctccaccgca tcctcaaacc
     2761 cggcggccgc ctcatcgcct cggtaaacca ccccaccgcc gactactgcc tggaacgcct
     2821 ctccggccgc agacccaact acttcaccac ctactcctcc cccgccgaat ggaccaccgg
     2881 cggccagacc atcaaagtca ccttctggaa ccgccccctc cacgccatga ccgacgcctt
     2941 caccaccgca ggcttccgcc tcaccaccct cagcgaaccc caacccctcc tcaccgccgc
     3001 ccccctctac cccgacggct acccgttgct caccaccgcc cccagcttcc tcttcttcgt
     3061 cctccacgcc gcctcgccca ccggctgacc tcgttggccc acaaacgatc ctggccgacc
     3121 tccgccgaca agggtgttct ggtcgtggaa ctcggctcga cggcccacgg gacaccgtgg
     3181 ggctgaagat cgcctcgaac ggccagttcg gcgccatcgt cgcgatagac acgctgcaca
     3241 ccctcgccca gcggttcgcc accttcacga tcaggctggt acccccacct gcgctcagct
     3301 ttgcgtgacg tccggtgaca cggcgcgggt gagccagtcg aagtagaccg cggacccttc
     3361 cgtgaccggg gtggcagtga cctcggggtt gtcccactcg tgctcggaga cgaggtggtc
     3421 ccgcaggtcg gcgaagcgcc cgctggtcgt cttgagcagg atctgccact cctcgccttc
     3481 tagtcgtgat catcagccct acaccgcctg gcgcggacgc tcctgcgtcc tcaccccggc
     3541 atggatcccc ccgaccccct cttccccgcc ctcccggagt tccgcggcga gttatcgaga
     3601 ccggcctcga ccggtatgtg ctcggcgacc gcaaaagcag tcctggctta tttggggtct
     3661 atgaaataga gcataatcgt cgcgggcgcc ctgaacgtta cggtggcggg ccgaatattt
     3721 cgatgacccg gcttcggcac gggaggtcga cctcaaatcc gattcaaggg ccgaatggcg
     3781 cgacgtcgga tcgggccatc cccgaccggt tggtcgcctc cactgatccg gtcagcccca
     3841 ctctggcgtc aaggctgcca aaggcttgtc gggtcgttgt acgttctcgc ccgtccggtc
     3901 ccgatcatcg aaaggtccca ccatgcgccg tctgctcttg gccgtctgcc tcgccaccgc
     3961 gggtgtcgcg ggggccctca cccccgccgc cgcggcacca ccgccggtca tccaccacgg
     4021 cccctacccc accgtcaccg agtgcgagac ccaggcccag gcctggcgcg actcggagac
     4081 cggccgcgcg gcctgggcca gcgagtgcca gcaccggagc acctcccagc tcccgacggg
     4141 ttggtacttc cgcaccctct acgccccgga gctccccatc cccaacctgc cctagtaccg
     4201 cgccccaccg ttcccaacgc ccccacgccc caacgcgtgg gggcgttggg ttttgacatg
     4261 gggcatggcg ccaccggggg tcgcgaccgg cgatcgtcag tagcgggttc cggtgccgtg
     4321 gggagacggc gccacgacgg cccggtgctc ggcctatggc gccgctgcct ggcgccagcc
     4381 ccggtacaag gcatcgaggt agccgagatg agcaagctgt tcgtagcggt ggccgcccgc
     4441 caaccgcgcc cccgcccagt ccgacgaccc cgacaccttc cgactcgatc gccacgacgc
     4501 gtcaacccac ctgacctccg gcgcgggtat ccacctgtgc gtcagcatga acctcgccca
     4561 cggaacgtcg tagaacgccg cgacactcag cggcaacaac tgcgccgatc gtgttgcggc
     4621 caattgtttc atttctagtt cagtccgacg ccgctcggac gtcacggcag ggaccggctg
     4681 ggaattccgg cattcttgag gtaaatccag ctgatgggga atacgaatag gccgcctttc
     4741 ggttggatta cgccatgtcg acgaatgctc acttctgccc tgtcgcgcct gtcactcctt
     4801 tgccaagtcg ggtcactctc ttgctgtcgg gtgctgtctt gacgctcgtc ttcaccgttg
     4861 tccacaatga agcgtgcggt gggcggcgac atggcctgcc tgccgcggga ccgggtcttc
     4921 ggagtattgc gtattagtcg cccaccattt ccccactgtg gcgataggag tcgtcgcgtt
     4981 gacttcaagc gtgggtgtct tgtgtggtcg ccgtcgatcc ggtcgccgat cgctcgtggt
     5041 ctcgggcgtt tcggtggtgc ggtcgtgttc gcgcgtcctg tcgcgccgcg cagggtagtt
     5101 cggggatgtc gcgggctgtc tgaaagggat ggacctcgga tgggtatcgg actgtcgcgg
     5161 gtgccgcgac gacgaggtgg ttggcggcgc ggggtggcgt tggcggtgag cgcgtcgctg
     5221 gcgtcagtgg ggttgctggc ggtgggggca cagcccgccg ccgcggcggt ggtgacgcat
     5281 ccgttcgcct acgtggccaa cagcggcggc aacacggtga ccgcgtacga ctcggtgacc
     5341 tccgctgtcg tgtcgacgat cgtggtgggt acgaccccgc tggacctggt cgccacaccg
     5401 gacggcgccc gcgtctacgt cacgaagaac agcggtgggg tgtcggtcat cgacaccgcc
     5461 accgcggccg tcgtggcctc catcggagtg ggttcgcagc cgaacgggat cgcgatcacc
     5521 cccgatggcg cgcgggtcgt ggtcgcgaac tccggctcga acacggtgtc gctgatcgcc
     5581 acggccacga acacggtgac cgcgaccgtc ccggtcggtt cacacccgac cggggtggcc
     5641 atcagtccca gcggggccac cgcgtacgtg accaacgacg cctcgggcac ggtctcggtc
     5701 gtcgacctcg ccgccgccgc ggtgatcgcc acgatcaacc tgggcctgca ccagcccatc
     5761 ggcgtggccg ccacccccga cgggtccacg gtgtacgtcg cgcagtacgg caacggcacg
     5821 gtcgcggtca tcgacaccgc caccaacacg gtgaccggca cgatcgccgt gggcgccatc
     5881 ccctcgggtg tggccgtcac ccccgacggt gcgcgtgcct atgtcagcaa catcggcccc
     5941 gacaccgtct cggtcatcga caccgccacc aacaccgtca ccgcgaccgt ctcggtcggg
     6001 agcaacccga gccgggtcgc cgtcagcggg gacggctcga cggtctacgc caccaacaac
     6061 ggggcgagtt cggtgtcgcg gatcgacgcc gcgaccaaca ccgtcaccac gaccttcggc
     6121 gtcggctccg gcccctacgg cgtgaccacc gcactcgtga gccagcctcg cgtcaccgcg
     6181 ctgagtccca cgagcggtcc gctcaccggc ggcacctcgg ttaccgtcac cggcaccgac
     6241 ctcgccgccg ccacgtcggt ccgcttcggc gcgacgtcgg cgtcgttcac cgtcgtcaac
     6301 aacaccaccg tcatcgccac cgccccggcc cacgccgcgg gcacggtcga tgtcaccgtc
     6361 gccaccccga cgggtaccag caccatcacg gccgccgacc agtacaccta cctcgacccc
     6421 acccccacca tcaccgcgat caacccggcc accggccccg ccgcgggtgg caccctggtg
     6481 accatcaccg gcacctactt caccggtgcc accgcggtca ccttcggcag cactgcggcg
     6541 gtctcgttca ccgtcaacag tgacaccagc atcaccgcca ccgcccccac cggcaccgcg
     6601 ggcacggtcg acgtcacggt caccaccccg gccggtgtca gtgccaccac cacggccgac
     6661 gactacacct acgtcgccgc acccacggtc accgccgtga gcccgaacgc gggcccgctc
     6721 ggcggcgggg gcacggtcac catcagcggc accgcgctga ccggggccac cgccgtccac
     6781 ttcggcgcga ccacggcgtc cttcaccgtc accagcgaca ccagcatcac cgccaccgca
     6841 cccccgggct cggcgggtac ggtcgacgtc accgtcacca ccatcggcgg caccagcacc
     6901 accagctccg ccgaccagta cacctacctg gccgcaccgg tcgtcaccgg cgtcagcccg
     6961 accagcggcc ccatcgcggg cggcaccaac gtcacgatca ccggcaccgg cttcaccggc
     7021 gcgaccgccg ttcggttcgg caccaccgcc gcgacatcgt tcacggtcac caactccacc
     7081 tccatcgccg cgatcgcgcc cgcgcacgtc gcgggcacgg tggacgtcac cgtcaccacc
     7141 gtcggcggca cgagcgcgtc caccaccgcg gaccggtaca catatctgga cgccgacctg
     7201 tcggtcacgg tggccgactc caccgacccg gtggccttgg gcggtgaccc gtacacctac
     7261 acggtcaccg cggccaacgc cggacccacc aacgccaccg gcgtgacgct atccaccacg
     7321 ctgaccggag ccgtgacgat caacttggtc acggcgtcgc aggggacgtg ctcgatcagc
     7381 tcgctcaccg tctcgtgctc ggtcggttcg gtcgccgccg ccgggtccgc gaacgtggct
     7441 atctcggtga caccgtcggc gacgggcacg gtcaccgcct cctcctcggt ctcggccacc
     7501 gagcccgact ccgtgccggg caacaacacc gacaccgagt ccaccaccgt caacaacgct
     7561 ctcggctgca cgatcgtggg caccagcggc aacgacgtcc tcaacggggg caacggcaat
     7621 gacgtgatct gcggcctcgg cggtgacgac gtcatcaacg gcggcaacaa cgacgacacc
     7681 atctacgcgg gtgcgggcga tgacgtgacc gatggcggca acgggaacga catcgtccac
     7741 gggggcgatg gcgacgacgt ggtcggcggt ggcaacggcg cggacaccat ctacggtgac
     7801 gcgggcaacg acacgaacta cggcgaaacc ttctggggct cgctgctgta cctgttcgac
     7861 aacggcaacg acgtcatcta cggcggcccc ggcaacgacg acctcgatgg ccagaacggc
     7921 aacgacacca tcgtcgacca cgacggcacc gacatcatga gcggctccaa cggcaacgac
     7981 accatcgacg tcctggacgg caccggcggc gacactgcca acggtggcct gggcagcgac
     8041 acctgctccg ccgacaccgg cgacaccaag accagctgct gacacccggt ccgccgcgcg
     8101 gtgccgacac cgcgcggcgg acccgggcac catcactcgc caggcaggag agcctcaccc
     8161 cagaccaagc gtcggcgcgc gccgacggac gcaccgaaga agacgttgcg gccgcgaccc
     8221 cggatggtcg cgtgctttcc cttcattcgg tctggcactc cacaccacgg cagcacgcca
     8281 cccaaggtcc taagaggaat gacgtgacgt cgtccacccc gggatcagcc gcgccgtccc
     8341 cgcgccgcga catccgcacc cgatggccgg tggcgcctgc tgccctcgtc caagccgtgc
     8401 tggcgatctt cgtcctggtc acgcccgcga gcgcggccag tgtcgacgtc gagagcttgg
     8461 gtaccttctc gcggagcttc tcccctccgg tcacgctcac cccgcagacc gtcaccgtgg
     8521 ccagcacatt cgactacgcc acgtgtcccg tgggatctcc ctcgaccggc accgggtcgt
     8581 tgtcgctggg ctgtgtcccg gtgacggtag gccccgccgc cgcggagaca atcacttggc
     8641 aggacaccac gggcggcacc agcacgatcg actgggcgtc cccggtcatc accggacaga
     8701 ccgtggtcta caccgggaca gtgagcgctg gccgccacgc gggagacacc gccaccaagg
     8761 tcacctcggg caccagctac ctcggcagcg tgatcgggtg ctcgttcggc acacccatct
     8821 ccagcaccac cggactggtt gacagtttcc tgctgaccca ctgattccct gccccctgcg
     8881 aaaccgtgca ttcgtcgtgg cgggggcggt tcgggcgccg tagccaggtg gagactcaca
     8941 actccacccc gaccacctct ccatggttct tctcggccaa gtaccgctgc catcacctgc
     9001 ggccaagccc gaggagaacg atcacgtggc agcgcgacta gcagccatcg aacgacggat
     9061 gatcgagatg gccgacgccc tcgacaggtt ccgagtcgac ctagccatga tcctccacaa
     9121 cacacgtcgc gactgacaga cttcacaggc cgtggtgcgg aacttgctgc gtgcaggcga
     9181 gtcgtcaaag cgccctgcgg ctttggcctc tagggctcgt gcgatggcca gcaagcgggt
     9241 ggacgaacac ccggtcccca ttgacgttga tgttctcgat cgactcgtgc ggctgacgac
     9301 cacccatccc caccaagtcg tccaccaccg cggccgtgac acgggcctcg acctccggag
     9361 acagcagtgt gtcgccgcgc cccagctcgc cgttggcgta ggtgtccgcg gcctcctgca
     9421 ctggcaccgc agcaagcgcg cggcgctcgg actgggttat cgccggtcga ccgaccgcgt
     9481 catctgcgat gacccggtcg ttgagctgcg cggtcacagc ttgacgcagc gcctcccagt
     9541 aggccccgcc ctggcggcct actccgctct ggccgcactc ctcgccccct tggtcgtcat
     9601 tgacgcccgc gaccagcgac tgcccaccaa gcccatgatc gtggccgctg ctaccaccac
     9661 gatcatgttc atcgccttcg ccgcagttga ccacgagcca ggacctcttc tccgcgccct
     9721 cgccagctca ggtacatgcg tgctcctgtt ggtcatcacc tacctgatca cttcagggtt
     9781 catcggaggc ggagacatcc gacttgcggc gctgctcgta ctagctctcg gctggacagg
     9841 ctggagcgcg gcagcccgca gcatcatgat tggcctgatc atcggcgcga tgtacagcca
     9901 gtacctccgg ctccgcctaa gactcggccc acttgcccat atcccgctcg gaccagcgct
     9961 cgctctcgga gcgctgagtt ccatcctcat cgactagttc tcacctcctc tcctggtcgt
    10021 gagttccgaa cacggcctct cgtgctgcgg cggcgaggcg actctgggtc tcgtaggaga
    10081 gcccaagccg gttccagtga aagatcacgt ggtgggccag cgtggctcga agacctcggg
    10141 tgagctggcc tcgtcgagca aagacgatca agctctcgcc agcgacgcgg aacgattcaa
    10201 cccacccagc aaggtgggct agctgaccac cagggcggac aagtgcgctg tctcggccca
    10261 tatcaactgc catgaggcgt tggaggtcgg tggccaacgt ccgttgttca tctggcgctg
    10321 gggattgtcc aggtcggttg ctggcgaccc gcgcccacac gtcgccttgt tcgtaccagt
    10381 cttgtcctgc tgctctgagg agttcgctgc atagcaggat gctgtgttcg cgacggtggt
    10441 tgagttcgtt ggggcggctg aggatctgtt ggctgtcgtg gtggaagagt cggtgcgctg
    10501 cggccatggc gttggtgccg ccgaaggcgt gaatctcagg ttcgtagatc gtctcgaccc
    10561 agtcggtgat ctctccggcg gagtggaggc tgttgagaga ttcgctgacg gtcttgcgga
    10621 gttcgttggc ttgagtggga tcggtcggga ggtagcgcag acgccagcaa ggtgccttgc
    10681 ggatgaacca ccatgacgcg gcccgttcca tgaccggcag cagccggtcg gctgtgatca
    10741 gctcggcttt tgagtagtcg gtgaactcga cactgatttg cagccactct ggatccatcg
    10801 actggcttct tccgttcgtg gtcggggtgt cacgagagga gaaggcaagc gtcccattgc
    10861 gaactggggc gcgtgtcggt gacaacagcg tggatggcca gcgcagcccc ggtgctgcct
    10921 tcgagtagtt cgccgtttcg ttgcgaggtc accagttgat ctgtcagcaa cgtggcaagc
    10981 ataggcaggt ggttgttgag ttcgtcggtg gcggcgtcgc gcgcgactcg ccatgtggtg
    11041 tacagcagcc ctgccgcacc gtggcacagg ctcgggtcga tgatacgggc gagctggtcg
    11101 gggtcgttca agcaattcaa cagcgcggcc tcggccgtgt gttgtcgtgt ggtgtcgtga
    11161 gtggccaatg cggcgacttg cagggcccgg acgatgccgg gtgtgccata gcaccacgat
    11221 ggttgggcag ggcctggttg atcacagcac ccggttcgcg cttcggccag tgtgatcgtg
    11281 cgaggccacc aagatcccgc gtcatgtggc tgttgccagg catccaacca ggcgcagatc
    11341 cgagcgatcg cctcggcgtg accggggact gcgactcctt ggcgtaacgc gagagcgagc
    11401 agggtcaagg ggccggtgat gccgtgcgcc atcccgaagt tgccgtgtcc gccagggtag
    11461 tcagttggtg cctgcccagt cgggccgtgt tcggtccacc accctggcag gtcgtcgccg
    11521 ggcagcgatt ccgtgagccg gacaaggtag atcagcacgt cccgggtgat gcggtgatcg
    11581 ggcgagcgaa gcaggaggta ggcgcctaga ccagtcaggc cgcggatgag gtcgaactcg
    11641 gccagtgcgg ggcgttcgcc gcggtcgatg cgggcgtgtg cggcggtgag acgggcgcga
    11701 gtgacctgtc gggtggcggt cgccaggtcg gcttgagcgt gctggtagcc gccggtggcc
    11761 tcggcggcgg cgtgagtaag gaaggcgagg gcgggcactc catagaacaa gcaggaactc
    11821 gggcttccgt caaggtcgtc gcaggcggct gtcgacagcc aggtgtgcgc cactgcgcgg
    11881 tgttcaggct gggtgaatgc gcgttcgatg tgcagaaggg cgataccggc gcttcctccg
    11941 gcgagtgact gcggtcgtgg agtgtggttg ccgacgtggg tggctggact gccgggttca
    12001 cccagttcga ccgcgatttc ctcggccaag ctggctagtg cgtggaggtt tcgcatcggc
    12061 ggcccttccg gtaactggtc tgactcaatg cggcggcgcg ggccaagcgg tggctggttc
    12121 gctcggcgtc tggtgagatg cccagggtgc ggacgctgtg caggtgcagc agcgagccca
    12181 gcaccgcgtt cggcgggggg cctcctgctt gggtgagcgc cgcacggtag ttcgctaccg
    12241 cggtccgccg tgctgtccac gcggtggcaa tctgctcacc gccgggcaag ttccggattg
    12301 ccgcctgctc agctcgcgga tctgacaggt gaagcgcttg gtcgtagacc cggcggtcgt
    12361 gtgcggaagc tgagccggtg gtgatgtgtt cgatcaacca cgtcgcagcc gcagcctggt
    12421 cgccggtgaa gccggttgcg aggtcgacca agctcgcggt gacaagcgcg cggtcgtcaa
    12481 cggcgccggg gcttgtcagg tgtgttcgtt gggcgagcgc gacgactgag tccgcagcga
    12541 acacatcttc cgctgcggcc atggtcgggc cgtgcccgaa gcggccggtc tccgggaggt
    12601 aggtgtccat ctgcatggtc gcgatcagcc cacgttggcg cagtcgcatt gcccacgcgc
    12661 cgagttcagc ggcgaccggg ccgaattgtg cggggtcggt gagccggatg cgcaggcgca
    12721 ggtggttgtc gggatcgcgg tagggcagga accaccactg caccgtttcg tccagtgtgg
    12781 gcagtagttc ggtgaggtag ctggcgagca cggcggagtg tcggtctggg tggccgtaga
    12841 gcttgcaata caaccactcg ccggcgccgg gtagatgccc gtcgtgcgcc gtggtcgcgt
    12901 ggaggggagt cgcacgaggc ggcaaagctg gccaagctcg gggtttcgtg gaggcgagcg
    12961 gcacgatgat ctcgtgggcg tgctcaccga tccagccgaa tgcgtcgtca cggggagctt
    13021 cctgcatggt ggcgtgcccg tgtcgatcaa gctgggcgcg caacaggtac aggtgagcag
    13081 cttcatcgag gttcaggcgc aagcgctggt cgtttccgcc gaggtagatc atggcgggcg
    13141 ccatcgccga ttcccgccac gcgtcgatcg ccgcgttcca ttccgcccac ggagcggact
    13201 tggcgggcag gtctgcggca ttaagggtcc agcgggccgg agccaagacg gtgcgtcggt
    13261 aggtcaagcg aggcaggaac ggtagctgtg tggcgatacc ccaggagaac ggtccccaag
    13321 ttgcggctct gccggtggtg agctcgcaga ccagacgcag tagcgggtgg gagaagttgg
    13381 tgaactcgac agcgctgaac acttccggtt ccaacggtcg tgctgtcgag cgtgaccaga
    13441 gagtgaatcg gtgcgcgtcc ccgatgacca ccaagtcctc tggcgcaaac tccctctcga
    13501 aggcaggccg gtactccccg atcggaatca ggttgggcag aacctgcgga tgacgggaga
    13561 cgttctccgt ctcggtgtag agcggtgggc aagacacttg aacgcgctgc ccatcggcgt
    13621 tgacggacgg caagtcggtg taggcgcgga ccatgcggtc ccgatcggac tcgtcgagca
    13681 tgtcgaggaa acggcccgcc gtggtgcccg ccgcccggaa cgctccggtc acgaccaggc
    13741 tgaagtcacc gcggccaagc gcggcagggc tgggcgcgtg cagccgaacg gcgagttcag
    13801 catgggcgaa tagttgggct tgaccgaagt tgggagcctc cagctcggtg atcgcggact
    13861 cgtcgaggat gacctcgact ctccggttca tggccgctgt ctgggccaat ctcagcaggg
    13921 ccacgtcccg atcgttggtt gccggtgcgg gaacgtcgag gagggagtcc cggtatccgg
    13981 ctggatagcc aaggcctaga tcggggtcgg ccagttccag cagcggtacg gcggcgccga
    14041 tgccgtaccg ctccaggaat cgtgcgtgga agtccaacca ccgtggcgcg ccgaagggat
    14101 ggggcgtcaa gcgcgccagc acgttcgcgg cgtgctcgac ttctctggcg accgtctcgg
    14161 gaagaactac ctgtgcgtcg actcgcatgt ccgttccgcc gtccgcaaca actgcggggc
    14221 gctcgtggag ccgggccacg atgccggacg tggccgggac ctgatcggcg tccacttggg
    14281 ccaaagcagt caggacgtgt cggactgggt cgacggaggt catgggtggg cgtaggccgg
    14341 tgagcagcac tcgctgttcg acgagcgtgg ccaccatcga ggcgatcgtc gttggcggca
    14401 catcggggaa ctcgttggag agtcgatcaa ccaggtcgga catgaggatc ggtgtgcgcg
    14461 cgttgcgcac gacgagggca atggcgcggg tgtagcggac ggtgacctcg gcggggtcgg
    14521 tccgggcggc atcggggttc gggtgctggc gcaggttgat gatcagcctg ccgtctcgct
    14581 cgacagccgt gttgttcagg actaccggca gccgcgtgat cagttcgtcg catcgctcca
    14641 gttcgctgac cagactggac aaccacactg cgtcaacccg ctcggtcaag tggtgctgat
    14701 caccgacgtg aacgagcgtg gtcggaccga acctgacggg tgccaccccc gcgaacagcc
    14761 cgaacggggt agcccggctg gaggcccgta gccggtagcg cagtagcgac agcaccgcgc
    14821 cacggacttg ccgaggtcgt acttccttcc cggcgcacac cgcggcgacg cggcgagcca
    14881 gatccgggct tgctgcgccc acggcgttgg cgaactgttc gtcggcccag gctcgcgcaa
    14941 gccatcctcg ccattgcggc acatcgcctg ccacgtctgg ccactcccct gctgtcaccg
    15001 gctgggtcgc cattcggagc atggccgcgt ccacgacggt gaacaccttg aacaccccct
    15061 caacatggat ggtggcctgg cgggaggtcc gctgcccctt gccgccaggc caccaccggt
    15121 cgacgccttg gatcagcagg tgctgttgga gcaggcgctc tgacaggtcg cgccgcagtt
    15181 gtcgtcggtg ctgcgcatca ggtcgggcac cacgggcccg gaggacacga tggtcaggtc
    15241 gaggtcgaac tcaccacctg acgcgaccgc ctggacgggc gccgactgcg tggagttgag
    15301 catggtggag ctccttcggg aactggtgaa tccttcgatg gggactacct ggccagaccg
    15361 tcaagacgag gtcggccagg agatcaggac gcgcgtgtgc ttcttgtcga tcaagcgccc
    15421 ctcaccgatc tcggtgtcgg gggtgccggt cgggtggacc tcgatgcggg cgccaggtcc
    15481 gccgcggtgg gtgcggtccc attcgcggat cagctcgacg taccggaagg ccacggcgtc
    15541 ggcatcaggt ccgtggccgt agacgacaaa ctcgaaggcg gtgcgctcct tggtggtggc
    15601 ctgtgaggcg cggtaggcga agctgacacc gtcgagcgcg gtcttggcgc ccatgcgcgc
    15661 cgagcgttcg gctagcccgg cctcgatcgc cgctggtgtg gccaccagca gcccgaatcc
    15721 atccagctcg gtggccaggt acaggtccag ctcatcgaac ggctcgaacc cgcccacctc
    15781 gaccccagac ggccgcacga cgcgctcgga ggtcagggca gcgctcaacg cgtcggcgtc
    15841 ggcggcctgg tcgccgtcca gccgcagggc gacgtcctcc ccgtgtagca gcaccagccg
    15901 ttcggcgttg gcgccagagc cctggatagg aacgaacccg cacagctcgt agccccggct
    15961 gaccaggcgt ccctgctcgc ggacgaatgc cactgaccgg gtgagcccgc gcatccgtag
    16021 cggaaccacc agcaccccgt cgggagcgag ctggtcgatc caggcgggcg ggatgtccca
    16081 ggccccggcg gtgacgatga tccggtcgaa cggggcgtgc tcaggcacgc ccccctcagc
    16141 gtcgaccagc agaacacgaa cgcggtcgta gccggcctca gcgaggcagg cccgcgcgcg
    16201 gtcgaccacg aactggtcga tgtccaccgt ggtgacctcg ccgtccggcc cgaccagctc
    16261 ggcgatgagc gccgcgttgt agccaccgga cccgatctcc agcacccgca tcccgggccg
    16321 gacctcggcc tgctccagca tcgacgcctg aatccgcgga gcggacaccg agctgaccgc
    16381 gagcccgttc tcgtcccgct tggtgatcac cacatcatcg cggtcataca cctgctccag
    16441 cggcgcctcc ggcgcgaaca actcacgcgg cactgtggcg aaggctcgga taacgggatc
    16501 tgtgcgcagt tccccctcgc tccgcaactg ctccaccatc gccgtcctga gcgcggcggc
    16561 gtccggggtg gtggtgtcgt tgtctcgtag tgtgttcact cggtcactct tccagtcgac
    16621 tttcgatgcc tcggcagtac gcgccgatgg gtcagagatc atcaccggtc cggctgacgc
    16681 gatgatcgtg atttccggcc agaccgcggc tacaggccgt gcagccctgc cagcacccgc
    16741 tccaacaccg ctcgacctgc ccatcgctac cctgacgttc cagactcaca gtgtccaccc
    16801 tcatagtgag cactgtataa ctgagcacgc tcagtttgcg gtacgccatt cgagtgaagt
    16861 agacaactgc acacgtcaac aaccaggagg aacccggtgg ttgcctcggc aagcagcagc
    16921 cccacggcac tcaagtggtg gttcgcggtg gagatgcgcc gtctccgcga gaaggcagac
    16981 ttgacgcgcg aagaggcggc cgccgccatc aagggcagcg ttcaaggtgt cgggcacatc
    17041 gagaccatga agtccctgcc caagccgctg gagctggaca agctgctgga gatctacggc
    17101 gtgccggaac gcgccgagtt cttccaagac ctgcgtgtcc gcgcgaagcg aggcaaggac
    17161 tggtggatcg gcttcagcgg ttcggtcccc tcccacctga acctcttcct tggcctggag
    17221 tccagcgcga tccagatcga gagctgggac gccaacctgg tgcccggcct cttccagaca
    17281 ccggagtacg cccacgcgac catcaaggcc gggcgccccg agctgcccgc ggccgaggtc
    17341 gaccggctcg tcgaactccg gatggctcgc cagcgccaag tccttgatcg agacaatccg
    17401 cccctggtgt ggtcggtcat cgccgagtcg gcgctgtcct ggcaggtagg cggctccgac
    17461 gtcgtgcgcg ggcagctcga acacctggcc gacctcacca ccagatccta cgtcgaggtg
    17521 caggttctgc cgttggcggc aggcgcgcac actggaaccg aaggcacgtt cacactgctc
    17581 tcggccccgc ccgagctgga gaactacgct gggtgtgcgt acgtcgaaga ccgcatcaag
    17641 ggccactact acgaggaggt ggagcagatc accacctacc gcaacgccct gacccggctc
    17701 cgggtcctgg cgatcaaccc gacagagtca ccggagtaca tccaccgact gataaaggat
    17761 ctgtgatcac catgaggtac gaggacgcag taaccgccct cgccgccgcg gccaactggc
    17821 acaagtccac ctacagcgga ggccagaacg gaggctgcgt cgaagtcggc tccgtacccg
    17881 gcctcgtggg agtccgagac accaagctcg gcgcgaacag ccccaccttg gccttttctt
    17941 cggtgaggtg ggcggcgttc accgacagcg tgaggtgcca tcagtccgac ctctgatcac
    18001 caggcagtgg acgccttcct ctgccaggct tcggctgccg ggccagcccc gttcctctcc
    18061 ccagcggtag ctggtgccac ggtaggagcg ccagtgtgct gtcgcgcttg gtgatgacat
    18121 gcccggcggg cagggggacc gtctggatgt tggcgggacg ggcgtggatt tgggatggag
    18181 ggtgcggtcg ttgtcccaac tgcggatctg ggacacagcc gtgcggcgag ctggtctccg
    18241 gtggggccgt gggcgtccag ctcgaagcgg gccgaggcgg cggtaagtga agtaggccag
    18301 gctgccgtcc tcggctagcg cggggctgcg ggagccgatg gccgggttgc acaggctgct
    18361 gtcgatcgcg gtctgcttgg cggcgatgcg gcaggtcgaa gtcggcagtc gtgtagcgcc
    18421 acccaccttg tacgagcagg ggacgagcga accgaaccct gccagggcct ctcggagaag
    18481 acgatgactg gcaacgacgt gggcgcatcc tcaccccagg cggacgagga gttcactgcg
    18541 gactggcaga gctgctcggc aacccctgat tgtcgtgggg tcgctatcgg ggacagcgat
    18601 cggtgtcttc gccatgtcga caacgaaggc cgcgcccgcg cgcttcaggc cgccaatgca
    18661 agtaaccgtt gggactgtct tcgtggcgtt cagatcgaca acgaactgct ccagcagatc
    18721 cggggcgtcg ctggcacgga cagacgcggg cgagaagaat ttcagagcct cgacgctact
    18781 ggtgcggtat ttaccgacta tgccgactgg tccggtgttg cgttcaccgg ctcaatggtc
    18841 agttttgccg atgccacctt cgcggctggc gcatcgtttc aagggagttc gttcccgaac
    18901 gatgcgctgt ttggtgcgac cacctttacg cgtggtgcgg acttcagtcg cgctgagttc
    18961 gccggtaggg ccttcttcaa gagtgctgac tttgacgatg atgcccgctt cgatgccgcg
    19021 accttcagtg ggccgctagt gctcaacgga accaaggtgc aaaaggatgc gaggttcgca
    19081 tacggcaagt ttgaggccag cgtctacttg cagcttgtgg aagttggagg aaatctcgac
    19141 ttttcctcag ggcgctttga ggatggactg acgatagagc actgtgctgt taagggcagg
    19201 tttgatctca cgaaggggca cgtggctggg ccatctgcgt gggcagacct caccgctatc
    19261 cagatggtca acctcagcag tgctgtcttc aacgaccccc ttgaagcaga gatcactacc
    19321 cgacacttgg cagcggtagc gacgaactgg cgtgctgacg tccggctgcg gctggcgggc
    19381 gcgaacgccg tcctcagtca tgccaccttc ggcgagccca gcaccatctc acggcgacgc
    19441 aacgccattg acttccagcc acactgggct gacaagcctg acttgatgac gtgcgagcca
    19501 cgcatcgtct cgttgatcgg tgcgaacgtc gacaagttga ccatcgccga cgtctcgatc
    19561 gctgcctgct gcctgaccga ggcacacaac ctggacaagc tccggcttga aggtgccgac
    19621 ctgcttgctc gcactccagc gaacagactg tggacgagtc ggctgaccat ctcggaagag
    19681 catgagtggc gggcaaagca ccaccacggt cgtcggcaac gcgactggtt tggcgcaccg
    19741 acgcaaccac acccatggga gaacacggac ttcagcaacc cccacccacc gacctcgcca
    19801 gagcgcatcg ccgagaccta ccgcagtctg cggaagtcac gtgaagacgc caaggacgag
    19861 cctggcgccg ccgacttcta ctacggcgag atggagatgc ggcgcgctgc gctcaaggtg
    19921 cgtcttgacg cgaaggaacg tgtagcgaca cagcgccaga cacgtcgctc agcccgcgtt
    19981 gagtacgggc tgctgaccct gtactggctt gtctccggct acggcctgcg cgcctggcgg
    20041 gcactggcga tcttcggcgt cctcgtgctg ctggcatcgt tctacttcgc ctggtgcggt
    20101 atccccgcag gtctgcccgc ggctggtgct gcttacatct cccggtgggg gcaaggactg
    20161 ctgatcgcgc ttgagtcggc cacgtcgctc atccgggcgc cgagcaagcc ggttacaacg
    20221 gcgggggagt gggctgtcct ggtgcttcgc taccttggcc cgctgctact cgcactcgca
    20281 gctcttgccg tgcgcgcacg ggtcaagcgg tagcgtccat agcagttctc gcaccacccg
    20341 tcacaaccag gtgctgacca gggaaaaccg agtcttccct ggtcagcacc tggtttggca
    20401 actttgacac ggtagtggtc aacgcgcgag caaggtgctg gcgatggcgg cttggattgg
    20461 gtcgagggtg gtttcgccgt cgtggaggga ccagagggtg ttttggagag tgcgggcgag
    20521 ggtccaggcc accgcagtag ggcggtctag ggagagggat tcagtgagga ggtcgaagcg
    20581 gtggagtagg gcggtggggg tgaggtaggc gttgtctagg gcgggcatta ggtcgaaggc
    20641 ggggtggccg gagatgggtt tggggtctat ggctagccag ggggtgcggg agctggcgag
    20701 gacgttgtcg tagtggaggt cccagtggag taggcggttg ccgggttcgc tgagggctgc
    20761 ggcggttgcg tcggcgcagg tgatggccag ggtgcgttcg gtggggttga ttaggcggtt
    20821 caacagaggg cgctcggcga gcattgcggt ggcgatgtcg gttagggtgc ggatccctgg
    20881 tggggcgggg acgtgtaggt gggatagaag gtctgcgatg acggcgatgc cctctgacgc
    20941 tgggagggcg ctcagggggc gcgaggcgtc gaggcgctct aggagcatgg cgccggttgg
    21001 ttcgtcgtgg tcgagtaggt ggaccgccgc gttgcctgcc cagtggcgca atgcaagtgg
    21061 ctcgccgtcg ttttcctcgt cgcggggctg gagcttcagg acggcgggtg tcctgtcagg
    21121 acggacaacg gggattacca aagcgaccat gccgtggcgc gcggggccgt ctaccttcag
    21181 ggaccaccgc tcgagcattg tgtcggccag cgtgggcagg gcgcgcagcc acggcaggtg
    21241 ttcagggctc tgcttcgcgt agtacgcggc aagggcgtca ggcacaggga tgggcacggc
    21301 tggatcctcc ttcgcgtgag tggacaaggc gaaggaggcg gcggcggtgc gcgaggtcaa
    21361 tggcccatgg aacccacctt agccaccgag tccgggatgc ggagggactc gaccaggtcg
    21421 cggtacaggg agtcggtggc caggagttcg gcgtgggtgc cgcgggctcg gatccggccc
    21481 tcggccatga cgatgatcgt gtcggcgtcg acgaccgtgg agagccggtg cgcgatggtg
    21541 accacggcgg cgtggaaggc gtgggcacgg atgacgtcgt gcagggcggc ctcggtcagg
    21601 ccgtcgacct gggcggtggc ctcgtccagc agcaggacgt ccgggtcggt cagcactgcg
    21661 cgggcaaggg cgatgcgttg gcgttgaccg cccgagacag acgtgcctga cagcggggtg
    21721 tccaggccct cgggcagcgt gtcggcgagg gtgtcgagcc ggacggcggc cagcgcgctc
    21781 tggagttggt cgtcggtggc gtcggggtgg gagaacagca ggttgtcgcg gatcgtgccg
    21841 gggacaaccg gtgtctcttg ctctacgtag gcgaggtggg ctcggatgtc ggcgtgggtg
    21901 aggtcccgat aaggaacacc gttgacgagc agcgagcctt cctggggctc taggaaccgc
    21961 aggatcaggg agaacaaggt ggtcttaccc gcgccggagg gccccacgat ggcggtatgc
    22021 cccacgcgcg gcacgtccaa gtcgatgccg cgcactgctg gcggggagtc gggcccgtag
    22081 gcggcggtga tgccccgaag ttccaacacc ggcccggtag tgcgaacggt ggcgttggtg
    22141 ctgacgcccg aggtctcgac cggtaggtcg tcgacctccc ggatgcgccc cgcggcggcg
    22201 atgccgttct gcagcgcggt gacgttctgg ctcagcgtgg tcaccggccc catcaggccg
    22261 aacgagtaga gcaggaacgc gatcagcgtc gacaccgcca tgtccccgtc ggacacccgc
    22321 cacgcgccga tcccgaggat caggatgatc gcgagctgga tgccgctcca cgagatggcc
    22381 caggcgatcg cctcccgccg gatcgcgcgg ataccctgct cggccgcgcc gcgtgcgtcg
    22441 gtgatgatcg tggcggtctg ccgctgctcg gcgcggctgg ccttgactgt gcgcactgct
    22501 cgcagcgcgc cttcgagggt cccaccgagc gcgccgacgt gggcctgcgc cttctccttg
    22561 gcgacggcga tcgcgggcat gagcagtccg aacaggatgg cgatggcgat cacggaggcg
    22621 accgtggtca ggaataggac caggtccagt gccgccatca gcacgagcgt gccgaccagc
    22681 atgaccacgc cgttgatcag gccgatgacg ctggcggcgg ccgcgtcgcg cagcaggagg
    22741 gtgtcggagg tgacccgggt gacgagctcg ccgggcgcgc gggtgctgat ggcggggacg
    22801 gtggcgcgga agaaccggtc gaccatgccc tggcgggcgg cgaggacgat gcgttcgccg
    22861 agggtgccca gcacgaccga ctgccaggtc cacatcacgg cgccgaccac gagcagcacg
    22921 gccatcagca cgatggggcc gcgcaggccg ccgtcggcgc ccagggagtc gaggacccac
    22981 ttggtggcca gcggggtggc caggccgacg ccggacccgg cgagggcgag caccagcccg
    23041 agagcgagtc gggcgcggtg gggacgggcg aaggaccaga ggacgcgaag ccgcccactt
    23101 ttcggaacgc tcatgctcga tagtggaaca tcgatgttcc acagcggtca agtggaatac
    23161 cgctgtgggc cgcggcgacc taggctgggc cggtggatct ccgcaccgca gccgacaccg
    23221 ggaccaaggc ccgcacccgc cgcgcgatcc tcgacgccgc ggtcaccgtg ctcaccgccg
    23281 atccggccgc gagcctgggc gacatcgccg ccgcggccgg ggtcgggcgc accaccgtgc
    23341 accggtactt cccagagcgc gccgacctga ccaccgcgct gcagcagatg ggctgggagc
    23401 acgtggtcca ggcgacccgg cgggcgcggc tcaccgaggg gaccggcgcg gacgggctgg
    23461 accggctctg ccaggagtac ttcgaactcg gcaacgtgct gatgctggtg ttcaactact
    23521 ccgcccccga cggcgacgtc acctgggact gcgaccccga cagccagtcc gtcctcgacc
    23581 tcatcacccg gggccaccgc gacggcagca tcgactccac cctgaccggc ccctggatcc
    23641 gcgacatcct ctgggccctg ctctacgccg cctggcagca gtcccggacc ggggtcgcgt
    23701 cccgccacca ggccctcgac tcgtgcctgc gcgcactgca caaggtcgtg gccccctgac
    23761 gcccgactcg gtcttcgccg acccgcgcct ggtggccgtc tacgacacct tcgacgcccc
    23821 gcgcgacgac ctcgacgcgt acgtggccct cgtcgccgaa ctcgacgcgc ggcgggtgct
    23881 cgacctgggc tgcggcaccg gcaacctggg cgttcggctc gcggaacgcg ggatcgacgt
    23941 gatcggggtc gaccctgcgg aggcgtcgct ggcggtggcg cgcggcaggg aagaacgggt
    24001 gcggtgggtg cacggggacg tcggctcggc ggcgggcttg gacgttgacc tggtcgtgat
    24061 gacgggcaac gtcgcgcagg tgttcctgac agacgcggag tggactgagg tgcttgcggg
    24121 ctgtcgggcg gcgacgcggc cgggcgggta cctggtgttc gagacccggc ggccgcagcg
    24181 gcgggcgtgg gaggagtggg acggccaggt ggtgctggac gtgccgggga tcggggcggt
    24241 ctcgcagcgg cgggaggtca ccgaggtgcg gctgccgctg gtgtccttcc gctcgaccta
    24301 tcggttcccg gacggcgcgg tgatctcctc gagcacaacc ctgcgcttcc gtgacctgga
    24361 cgagatctcg cgggatctcg ccgcgcacgg gtaccgcgtg ctcgacgtcc gtgaggcgcc
    24421 ggaccggccg ggcaaggagt tcgtgttcgt cgctcaggcc agcgctttgg tcatgaacac
    24481 gctgttgggg tcttccacgt agggcgggaa agggccgcag aaggtgaacc cgtacttcgc
    24541 gtagagggcc cgcgccgggg cgaagaactc gaacgacccc gtctccaggc tcagccgctc
    24601 gtacccgcgc tcggtcgcga ccccgacgat gtgccgcaac accaacgacg ccaccccgcg
    24661 cttgcggtac tcccccgccg tccgcatcga cttgacctcc ccatgccccg gcgccaactc
    24721 cttgagcgca ccgcacccgg cgagcacgtc cccgtcgcgg accgcccaga acgtcacctc
    24781 gggcttccgc aacccctcaa gatccaacgc gtgcgaactc cccggcggtg tcacggcccg
    24841 cagttgctcg acgtgctcct ccaggaaccg cgccacctcc gcacctgaca ggtcgtccac
    24901 caccacacgc aactcgccca tgcgggaagc atcgcaccta cggctccgct gctggtcagg
    24961 tgagaggagt gccctgccag tgccaggcgg tttggcgggg cttgcctggt aggtctatcc
    25021 ggttggtcgc ccacaacagg gctgtccatg ggtcg
//
