LOCUS       NZ_JAMTCR010000002     22486 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Actinokineospora globicatena strain DSM 44256
            LV79DRAFT_scaffold00001.1, whole genome shotgun sequence.
ACCESSION   NZ_JAMTCR010000002
VERSION     NZ_JAMTCR010000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinokineospora globicatena
  ORGANISM  Actinokineospora globicatena
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Actinokineospora.
REFERENCE   1  (bases 1 to 3058629)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3058629)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 3058629)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUN-2022) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
REFERENCE   4  (bases 1 to 3058629)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Wang,J., Palaniappan,K.,
            Ritter,S., Chen,I.-M., Stamatis,D., Reddy,T., O'Malley,R., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUN-2022) Prokaryote Super Program, DOE Joint Genome
            Institute, 1 Cyclotron Road, Mail Stop: 91R0183, Berkeley, CA 94720,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: AllPaths v. r46652
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 261.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024171945.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 06:43:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,731
            CDSs (total)                      :: 6,666
            Genes (coding)                    :: 6,609
            CDSs (with protein)               :: 6,609
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 8 of 57
            Pseudo Genes (incomplete)         :: 49 of 57
            Pseudo Genes (internal stop)      :: 2 of 57
            Pseudo Genes (multiple problems)  :: 1 of 57
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:43:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 254098
            Orig. end                         :: 276584
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAMTCR010000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22486
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22486
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22486
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12486]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12486
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(224..1444)
                     /locus_tag="LV79_RS01235"
                     /old_locus_tag="LV79_000241"
     CDS             complement(224..1444)
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005466189.1"
                     /locus_tag="LV79_RS01235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000241"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_253831333.1"
                     /transl_table=11
                     /translation="MPEAVIVSAVRSPIGRAGKGSLVDIRPDDLTAQMVRAALDRVPAL
                     DPADIDDLMLGCGLPGGEQGNNMGRVVAVLLGYDSLPACTVTRYCASSLQTTRMALHAI
                     KAGEGEVFISAGVEAVSRFAKGSSDSWPDTHNPIFAEAEARTAAVAESGADEWHDPRLD
                     GRVPNAYIAMGQTAENLALAKGITREEMDHFGVRSQNRAEQAIESGFWAREITPVTLPD
                     GRVVETDDGPRAGITYEKTATLKPVFRPDGRVTAGNCCPLNDGAAALVIMSDRKAAELG
                     LTPLARIVSTGVSGLSPEIMGLGPVEASRQALARAGLSISDIDLVEINEAFAAQVIPSA
                     RELGVDEDRLNVNGGAIAVGHPFGMTGARIATTLINSLQWHDKQFGLETMCVGGGQGMA
                     MVLERLS"
     gene            complement(1528..2340)
                     /locus_tag="LV79_RS01240"
                     /old_locus_tag="LV79_000242"
     CDS             complement(1528..2340)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018683239.1"
                     /locus_tag="LV79_RS01240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000242"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_253831334.1"
                     /transl_table=11
                     /translation="MLWIRGLWVAAVAAGSVGGLSGAAYTLLQSQSRQARSVIGVPRDL
                     PFNADGGYLPDGSGPLTVTDPLTFGIFGDSTAAGLGAESPEALPGVQLAKGLAEESNRP
                     VQLTTYAVVGSRSTHLADQIDRALLDPPKAAVVMVGGNDVTARLGVNACAELLGQQVRR
                     LVAAGTGVVVGTCPDLGAVRPIPQPLRSLAQRWSLALGRAQARELAGSGAAVVPMTLVS
                     RHFARRPDELFSPDRFHPNGAGYGLAASVILAPLCAVAGVCHSAVTPG"
     misc_feature    complement(1954..1956)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            2510..3889
                     /locus_tag="LV79_RS01245"
                     /old_locus_tag="LV79_000243"
     CDS             2510..3889
                     /EC_number="4.2.1.22"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004122 - cystathionine beta-synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019343 - cysteine biosynthetic process via
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229841.1"
                     /locus_tag="LV79_RS01245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000243"
                     /product="cystathionine beta-synthase"
                     /protein_id="WP_253831335.1"
                     /sec_met_domain="PALP (E-value: 7.3e-71, bitscore: 236.2,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYVEHIIDLVGDTPLVKLNSLADGLAPTVLAKVEYFNPGGSVKD
                     RIALRMVEAAEASGELRPGGTIVEPTSGNTGVGLALVAQRKGYKCVFVCPDKVSEDKRN
                     VLKAYGAEVVVCPTAVAPEHPDSYYNVSDRLVREIDGAWKPNQYANPENPESHYRSTGP
                     ELWQQTDGKITHFVAGVGTGGTISGTGRYLKEVSGGKVQVIGADPEGSVYSGGTGRPYL
                     VEGVGEDFWPETYDRSVADEIIAVSDSESFEVTRRLAREEGLLVGGSCGMAAAAALRLA
                     KRLGPDDVVVVLLPDGGRGYLSKVFNDSWMAQYGFLPPEHSGATVGDVLRRKSASGTTI
                     PDFVHAHPTETVADAVAILREFGVSQMPVVNAEPPVMAAEVVGAVNERDLLDALFTGKA
                     ALADRLDRHMSGPLPTIGAGEQVSVAMKALTDADGALVLVDGKPAGVVTRQDLLGFLAG
                     R"
     gene            4009..5280
                     /locus_tag="LV79_RS01250"
                     /old_locus_tag="LV79_000244"
     CDS             4009..5280
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009083189.1"
                     /locus_tag="LV79_RS01250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000244"
                     /product="hypothetical protein"
                     /protein_id="WP_253831336.1"
                     /transl_table=11
                     /translation="MSAPQPPNQPWQGGQPQQWPGQPGQDQQPYGQQPGGYPPPQPHYA
                     PPPGDTTGADGVERTQAIRPGQTPPGGEEEGVDRTQVVRPGQGDATQMVPPGSVPQSPP
                     YAPPPSAADQASPPGGFHQPYGQQPPPQQQYGQPGGFGQQQGYGQQQPGGYPGQPGGFA
                     QQPGLGGAPGAGGQGQNTGMIALIVLGAVAVLGLIALIMSISLMSNLSTISGLCGDVSG
                     LGGLASSYCPSGFNTFLAFVQIAGAGVAIAGAVLLALKKNLNIAHLLVVGGGGALVVAA
                     IINGATFSFVGQIMTPLVFGLLIAGAGALAFFPQTKDYLLGSSPLSSLSGGGGHGGPGG
                     PGSSGGPGGFGQQQGFGQPQQQQQYGQPGGYGQQQPPQQQGYGQPGGYGQQQQPGYGQQ
                     PPPPPPGGGFGQQPPGGQQPPQQW"
     gene            5363..5866
                     /locus_tag="LV79_RS01255"
                     /old_locus_tag="LV79_000245"
     CDS             5363..5866
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS01255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_000245"
                     /product="hypothetical protein"
                     /protein_id="WP_253831337.1"
                     /transl_table=11
                     /translation="MNYQAQGYYPQFQQTSPGSPGTSVLAGIGALGIAAGMGGASAYFL
                     AEVPTARDIFALPAGLQSLLIGRMVLAALALIGAILLFTRRRAGVPLVALTAVASVASL
                     PLEPLISELLRGIGITVSGYFEALLEFNDTYTILLAVGAATGLIAFLFAILPATSRWLR
                     TPRY"
     misc_feature    complement(5387..5403)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.12"
                     /tool="antismash"
     misc_feature    complement(6163..6180)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.66"
                     /tool="antismash"
     misc_feature    6258..6273
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: medium, score: 25.01"
                     /tool="antismash"
     misc_feature    6305..6323
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.37"
                     /tool="antismash"
     misc_feature    complement(6402..6416)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.26"
                     /tool="antismash"
     misc_feature    complement(6415..6429)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 21.93"
                     /tool="antismash"
     misc_feature    6416..6430
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 23.21"
                     /tool="antismash"
     gene            6470..7627
                     /locus_tag="LV79_RS01260"
                     /old_locus_tag="LV79_000246"
     CDS             6470..7627
                     /EC_number="2.5.1.48"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /NRPS_PKS="Domain: Beta_elim_lyase (55-182). E-value:
                     6.3e-07. Score: 20.8. Matches aSDomain:
                     nrpspksdomains_LV79_RS01260_Beta_elim_lyase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020631466.1"
                     /locus_tag="LV79_RS01260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000246"
                     /product="cystathionine gamma-synthase"
                     /protein_id="WP_253831338.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.7e-12,
                     bitscore: 44.6, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADETSRWGFETRAIHAGQEPDPRTGAVIVPIYATSTFVQDGVGG
                     VRDGGYEYSRSANPTRTALEQALAALEGGKHGLAFASGLAASDVALRSMTRPGDHVILG
                     NDAYGGTFRLLDKVLTQWGVEYTSVDLADLTATRAALRPTTKVIWSETPTNPLLGVADI
                     AALAAVAAEGGAKLVIDNTFATPYLQSPLGLGADVVLHSTTKYLGGHSDVVGGALITSD
                     DELRDKFTFLRNAAGAVPSPFDAWLVLRGAKTLALRMERHSDNAERIVEVLLGHQKVTK
                     VYYPGLPEHPGHEIAAKQMRRFGGMVSFSVAGGEEAALAIAARTKLFLLAESLGGIESL
                     IEHPGKMTHASTTGSPLQIAGDILRLSVGIEDGTDLVNDLLKALD"
     aSDomain        6635..7015
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LV79_RS01260_Beta_elim_lyase.1"
                     /evalue="6.30E-07"
                     /label="LV79_RS01260_Beta_elim_lyase.1"
                     /locus_tag="LV79_RS01260"
                     /protein_end="182"
                     /protein_start="55"
                     /score="20.8"
                     /tool="antismash"
                     /translation="SANPTRTALEQALAALEGGKHGLAFASGLAASDVALRSMTRPGDH
                     VILGNDAYGGTFRLLDKVLTQWGVEYTSVDLADLTATRAALRPTTKVIWSETPTNPLLG
                     VADIAALAAVAAEGGAKLVIDNT"
     gene            complement(7703..7954)
                     /locus_tag="LV79_RS01265"
                     /old_locus_tag="LV79_000247"
     CDS             complement(7703..7954)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS01265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_000247"
                     /product="hypothetical protein"
                     /protein_id="WP_253831339.1"
                     /transl_table=11
                     /translation="MATSRRTMPLAGAAAAALVLAGVAVFTVSNAGCASAGEFVQRGQG
                     LELVGGCVDPADLPAAPSTPTVGTNPGSAVERFHQTSP"
     gene            complement(8079..9281)
                     /gene="hppD"
                     /locus_tag="LV79_RS01270"
                     /old_locus_tag="LV79_000248"
     CDS             complement(8079..9281)
                     /EC_number="1.13.11.27"
                     /GO_function="GO:0003868 - 4-hydroxyphenylpyruvate
                     dioxygenase activity [Evidence IEA]"
                     /GO_process="GO:0006559 - L-phenylalanine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hppD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009950489.1"
                     /locus_tag="LV79_RS01270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000248"
                     /product="4-hydroxyphenylpyruvate dioxygenase"
                     /protein_id="WP_253831340.1"
                     /transl_table=11
                     /translation="MTGTLNRGDQGMDEVSFDQLRQLVGLVEYDESKDPFPVRAMDAVV
                     FVVGNATQTALFYQSAFGMTQVAYSGPETGNRDHKAYVLKSGSARFVIKGGVDPKSPLL
                     DHQRAHGDGVVDLALEVTDVDKCLAHARAQGAIVLEEAHDVTDEHGTIRVGAIATYGKT
                     RHTLVDRSRYNGVYLPGYVEKAGSYKKPEGAPKRIFQAVDHCVGNVELGKMDYWVDWYN
                     RVMGFVNMAEFVGDDIATEYSALMSKVVANGNHRVKFPLNEPAIAKKKSQIDEYLEFYG
                     GPGCQHIALATNDIIATVTAMRAAGVEFLDVPDSYYEDPELRERIGNVRVPIEQLKEHA
                     ILVDRDEDGYLLQIFTKPTGDRPTVFYEMIERHGSLGFGKGNFKALFEAIEREQDRRGN
                     L"
     misc_feature    complement(9294..9305)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.75"
                     /tool="antismash"
     gene            9436..9924
                     /locus_tag="LV79_RS01275"
                     /old_locus_tag="LV79_000249"
     CDS             9436..9924
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005167940.1"
                     /locus_tag="LV79_RS01275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000249"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_253831341.1"
                     /transl_table=11
                     /translation="MTEESPGIDDLDARLLLLLTDEPRLGVLECSRRLGVARGTVQARM
                     DRLDRRGVLTGFPPAVDLAAMGYGLTAFAVLEIAQGKRGEVATRLHAIPEVCEVHATTG
                     EGDLLVRMVAQNNADLQRVIDRVVNVEWVRRTSTSIALSTPIPPRVRPLLERAVRQSG"
     gene            complement(10001..11074)
                     /locus_tag="LV79_RS01280"
                     /old_locus_tag="LV79_000250"
     CDS             complement(10001..11074)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="LV79_RS01280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000250"
                     /product="hypothetical protein"
                     /protein_id="WP_253831342.1"
                     /sec_met_domain="T1TS (E-value: 1.1e-44, bitscore: 150.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNSSHPGAGLRYGMTYRLPALPTRSPLALHPEFTATAPRVLAWL
                     RPHLVDYFGESEQDSPITDRYLRQDLHRWGALCMPHTRPDRFFAQQLWMNAAALLDDAF
                     SAPWLREQPARDLLARQLCAAVEAAPGGATPLARLLSDVHALLLPDSGSLRQRLIDVGK
                     TVVIDNANQNTVEEFDDLDAYLGSSRRVNAYGFWILALAEWALGIDLDGLASQDPLVHK
                     ACTLAIDHWVLVNDLYSFAKEIEEGEKINAVWVLLGQGAPLQEALDAIAARAVATEERF
                     IATRDRVATGPLRHRDDVARFLVEVGHMISGNLRHARESSRYHGDGRRIDDDLAGNTSA
                     EHRTLHRIGTVHEPLVD"
     misc_feature    complement(10304..10306)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    11066..11079
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.12"
                     /tool="antismash"
     misc_feature    11087..11100
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.74"
                     /tool="antismash"
     misc_feature    complement(11088..11101)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.83"
                     /tool="antismash"
     misc_feature    complement(11089..11102)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.64"
                     /tool="antismash"
     misc_feature    11093..11108
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 21.05"
                     /tool="antismash"
     misc_feature    complement(11304..11318)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.89"
                     /tool="antismash"
     gene            11476..12486
                     /locus_tag="LV79_RS01285"
                     /old_locus_tag="LV79_000251"
     CDS             11476..12486
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944750.1"
                     /locus_tag="LV79_RS01285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000251"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_253831343.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 8.6e-57, bitscore:
                     189.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGPGTEQLLATSRAAVLPALRAAVDSLPPAMRRIACYHFGWVDAC
                     GAPIEADSGKMVRSALTLLSAEAVGGDPADAVPAAVAIELVHNFSLLHDDIMDGDRTRR
                     HRGTAWAVFGVPAALLAGDALWALALRVLAAGPHADRALPLLTEALWRLMDGQSADADF
                     PHRHSVTLAECEAMAAGKTGAVMACATALGALFGGATPDQLALLRDMGEHLGLAFQLVD
                     DLLGIWGDPTTTGKPGADLVHRKRSLPVVAALTSNTPAGAELATLYLATDHPMTTPEQT
                     RAATLITTAGGRTWATTQAELHLAQATTALRRTNPPAPALANLLALADHFAHRTS"
     gene            complement(13240..14112)
                     /locus_tag="LV79_RS01290"
                     /old_locus_tag="LV79_000252"
     CDS             complement(13240..14112)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS01290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_000252"
                     /product="hypothetical protein"
                     /protein_id="WP_253831344.1"
                     /transl_table=11
                     /translation="MGPQQDHPEFGVSRHGYDRTQVKRYLGTLADQHAAITAERDEALA
                     RAEEVDGQLQLARREIAALTERLDKIGNAAAASSAPNAAERAARTIATAEAQAREITAR
                     AEAAADTAWSAAEAASVALRDRYRALMADAEKRHAELHTAHAEFMAETRTKVDDMTTAA
                     TARQRTTDDQAERDRQRLEQAFQQELATRRSDLDTEVTTARATATAEAAALVQAATDEA
                     DKRIATATSQVERLTALREQLAGRLRGTSELLTQSSQLLQPLEAESELDETTANAPTAK
                     NLPLPQTTS"
     gene            complement(14258..15217)
                     /locus_tag="LV79_RS01295"
                     /old_locus_tag="LV79_000253"
     CDS             complement(14258..15217)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009073109.1"
                     /locus_tag="LV79_RS01295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000253"
                     /product="ATP-binding protein"
                     /protein_id="WP_253831345.1"
                     /transl_table=11
                     /translation="MKIAFVGKGGSGKTTLASLFLRHLAAETPTPPLLGIDADINQHLA
                     AALGAADDHTQPTLGEHLTAIKDHLRGDNPLVHSAADMIKTTPPGRGSRLIGIDDDNPL
                     YARFVRRVDGVRLAATGPFAESDLGVSCYHSKVGAVELLLNHMVDGAGEYAVVDMTAGA
                     DSFASGLFTRFDVTFLVCEPTLRSVGVYRQYLDYARDFDVRVAVVGNKVIDADDVAFLR
                     QHVGADLLTWIGRSDHVRAAERGDIRPVERLEPANREALRAMRALVDGVEQDWPKFHRQ
                     TVEFHLRNASAWANGRAGRDLAEQVDPGFVPGPVSLAG"
     misc_feature    complement(15258..15273)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.53"
                     /tool="antismash"
     misc_feature    15261..15276
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.57"
                     /tool="antismash"
     misc_feature    complement(15266..15279)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.78"
                     /tool="antismash"
     misc_feature    15266..15280
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.56"
                     /tool="antismash"
     misc_feature    15267..15280
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.63"
                     /tool="antismash"
     gene            complement(15305..16432)
                     /locus_tag="LV79_RS01300"
                     /old_locus_tag="LV79_000254"
     CDS             complement(15305..16432)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018683243.1"
                     /locus_tag="LV79_RS01300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000254"
                     /product="polysaccharide deacetylase"
                     /protein_id="WP_253831346.1"
                     /transl_table=11
                     /translation="MTTRRRWEIVAVGVALALAFVILVVVGTVRPQPQTRVLEAEPHPQ
                     ASAGPPKWMRKLNPGEKPPQFVLFSFDGAGSHEHWQKFLPLARSVNAHFSGFLSGIYLL
                     TDEQKAEYTGPGHKPGRASIGFGGTQQDVQALIGDLNAAVDQGNEVGTHYNGHFCQGAE
                     PGVGRWDAAQWNSELDQFFAFVDRGRAQGLKVDPKAIKGGRTPCLEGQFDVLLPVLASR
                     GMTYDTSQVSDGLAWPTTQHGVWEFAMPSVRVPGLKYKKTIMMDYNFWYLLNKAKDDPS
                     RAPEFTAVVQETYERAYQAAFDGNRAPMVVGNHFNNWSGGAFTAATEKFMGSVCAKPET
                     VCATYSEVVEWLALQDPAVLDAFRAMPNAQIAQPS"
     gene            complement(16572..17333)
                     /locus_tag="LV79_RS01305"
                     /old_locus_tag="LV79_000255"
     CDS             complement(16572..17333)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018683244.1"
                     /locus_tag="LV79_RS01305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000255"
                     /product="class F sortase"
                     /protein_id="WP_253831347.1"
                     /transl_table=11
                     /translation="MARRSSTLAPPAVAGGAGVLVLLVCGLTFASPTPVQGLPLPAQPG
                     LQLTAIRKAANESDAALAGLRSQIKPKPAEPAPSVEPSAPPPTSTTTPPAAEAPPPPRQ
                     PVAGQRPGTLRLAKGGTATLVRKELGPDATLPVPSGVKEATWWGAGLDAPTGASVFAGH
                     VNWKGATGPFSELWSSRVGDLVSVVDDKGTQWRYRVTRVETVSKHDLPARAEEFFGQTG
                     PHRVVLVTCGGQWVGGSDGYESNRVVIAVPA"
     gene            complement(17340..18812)
                     /locus_tag="LV79_RS01310"
                     /old_locus_tag="LV79_000256"
     CDS             complement(17340..18812)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028852.1"
                     /locus_tag="LV79_RS01310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000256"
                     /product="collagen binding domain-containing protein"
                     /protein_id="WP_253831348.1"
                     /transl_table=11
                     /translation="MRRSTLGARLSSAVATVATLSAALLVVGAPPAAAEYKKGPGIGVA
                     LQPYKDPPREATEDWLGSYLVNGKQVWCVKFAFKEPDTNEVYQPSDVLKTKYGAALDPV
                     HAADISYLLLRYADTKDTAESAALAHLLHQWTAAPRTPADLDPATNGFRTIAYNVPFHE
                     RALEEKLPGAMRTVAKLRADATANHGPWTPLLTKPTKPQVIGTPDTWPIEVRGAGGSGV
                     GKVPVKVVLTDATSGGKTELTATTKDNGGPIALEVVPTGPKPSVSISLLAPADQPVVQH
                     AVEDGTQSVVSTGGEKELKAAADTTAVTAPGQVAVAKVDEKTGQGIASVSLKVTGADKT
                     TPAVDQDGKPLVGADGKPLVVVTGADGKATVPNLRTPQEVCVTEVAAPPGYEQSYDPNN
                     PPSACGKLEPGKTVELRLVNKPNVPTVPQTIPAGDGPANAAAVLDAGGPSTGLLVALGA
                     LLLFAAGAGTALVRKGRGPIVVGRRMRKDWGH"
     misc_feature    complement(18741..18743)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19223..20032
                     /locus_tag="LV79_RS01315"
                     /old_locus_tag="LV79_000257"
     CDS             19223..20032
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156027.1"
                     /locus_tag="LV79_RS01315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000257"
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="WP_253831349.1"
                     /transl_table=11
                     /translation="MRSTSNPAFRNLPQGGYAGFQPQAQGYQDQGYPPGYGSPSAPAGT
                     GDRPMTVDDVVTKTAATLGVALVVGIITAVLVLGKDISPYPPMIIGAIVGLVISLVIIF
                     KKTPSPALVLTYSAAEGLFLGAITGVFEMFVPGIAFQAILGTALVFITMLVVYKTGAIK
                     VTPKLTKWIIGATVGAAGLMLVNLVLSMFGVNMGIRDAGPLGIGISLLFIGIAAFNFLL
                     DFDMADQMIRSGTPSKFAWYVAFGLMTTLVWLYLEILRLLYMLQSSD"
     gene            20105..20491
                     /locus_tag="LV79_RS01320"
                     /old_locus_tag="LV79_000258"
     CDS             20105..20491
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LV79_RS01320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LV79_000258"
                     /product="hypothetical protein"
                     /protein_id="WP_253831350.1"
                     /transl_table=11
                     /translation="MRALISWLLCLAGVAVVGFGAFRPWYEGRAGNTLPLSDLFSGVSR
                     ESAPVLGSLTLPLAIGVLLAVVGMFRAKGILQLGGVILAATMIGWVVQAREVVDLGDLQ
                     LGAWNALFGSLLVLASGIMRPGRV"
     gene            complement(20496..22250)
                     /locus_tag="LV79_RS01325"
                     /old_locus_tag="LV79_000259"
     CDS             complement(20496..22250)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (35-286). E-value:
                     2.6e-22. Score: 71.5. Matches aSDomain:
                     nrpspksdomains_LV79_RS01325_Abhydrolase_1.1"
                     /NRPS_PKS="Domain: PKS_KR (323-481). E-value: 7.8e-11.
                     Score: 34.1. Matches aSDomain:
                     nrpspksdomains_LV79_RS01325_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018683248.1"
                     /locus_tag="LV79_RS01325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LV79_000259"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_253831351.1"
                     /sec_met_domain="PF00561 (E-value: 2.9e-15, bitscore: 53.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.8e-14, bitscore:
                     51.1, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 6.8e-32, bitscore:
                     108.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSEPRPLPATGPRRRTVSNDGVELAVFSEGDPASPTILLVHGFP
                     DTHRLWDGLAERLIGDYHVVRYDVRGAGASTAPRKTAEYRTELLAEDLFAVADAVSPNR
                     PVHVVAHDWGSIQAWAAVTAPRAKARIASFTSVSGPNLDHVGQWVRRRVTRPTPANLRQ
                     VVAQLTHSWYIALFHIPVLPGLAWRTVVGPRWGHLLRRMEGVEATPAPTIGTDAANGVR
                     LYRANMLSRRSRPAPSPAEVPIQVVLPTRDRFVTAALAEDLERWIPRLWRRRLVAGHWV
                     PLSHPEALARVVEDFVEHVSGAPMTRSLQRARAGRDEGFTNRLVVVTGAGKGIGRATAL
                     AFAARGAEVVVADIDIEAARRTAAEIGPAAYPHPVDVSDADAVRAFAEDITDQHGAPDI
                     VVNNAGIGMAGPFLATTAQDWRRVTDVNLLGVVNGCREFGALMAEAGEGGHIVNISSAA
                     AYTPSRSLSAYAASKAAVLALSDCVRAEFADHGIGVTAICPGVVATDITNTTTFTGTDD
                     LGQQRMRQQATKAYARRGFTPDRVAEEIVRAVERGTPVVAVTPEAKLARAGARFFPGLM
                     RRVARVLG"
     aSDomain        complement(20808..21281)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LV79_RS01325_PKS_KR.1"
                     /evalue="7.80E-11"
                     /label="LV79_RS01325_PKS_KR.1"
                     /locus_tag="LV79_RS01325"
                     /protein_end="481"
                     /protein_start="323"
                     /score="34.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LVVVTGAGKGIGRATALAFAARGAEVVVADIDIEAARRTAAEIGP
                     AAYPHPVDVSDADAVRAFAEDITDQHGAPDIVVNNAGIGMAGPFLATTAQDWRRVTDVN
                     LLGVVNGCREFGALMAEAGEGGHIVNISSAAAYTPSRSLSAYAASKAAVLALSD"
     misc_feature    complement(20820..20822)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       complement(21198..21275)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LV79_RS01325_0001"
                     /evalue="2.40E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="LV79_RS01325"
                     /protein_end="351"
                     /protein_start="325"
                     /score="13.8"
                     /tool="antismash"
                     /translation="VVTGAGKGIGRATALAFAARGAEVVV"
     aSDomain        complement(21393..22145)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LV79_RS01325_Abhydrolase_1.1"
                     /evalue="2.60E-22"
                     /label="LV79_RS01325_Abhydrolase_1.1"
                     /locus_tag="LV79_RS01325"
                     /protein_end="286"
                     /protein_start="35"
                     /score="71.5"
                     /tool="antismash"
                     /translation="PTILLVHGFPDTHRLWDGLAERLIGDYHVVRYDVRGAGASTAPRK
                     TAEYRTELLAEDLFAVADAVSPNRPVHVVAHDWGSIQAWAAVTAPRAKARIASFTSVSG
                     PNLDHVGQWVRRRVTRPTPANLRQVVAQLTHSWYIALFHIPVLPGLAWRTVVGPRWGHL
                     LRRMEGVEATPAPTIGTDAANGVRLYRANMLSRRSRPAPSPAEVPIQVVLPTRDRFVTA
                     ALAEDLERWIPRLWRRRLVAGHWVPLSHP"
ORIGIN
        1 agtacgagct ccccaacggc aagacccaga aggtcaccct gaccagggcg gtcccgtacg
       61 gcggctgaca caagccacag caacagcgag acggccaccc cacgtgccga tggggtggcc
      121 gtcttgttgt gtcagggcaa ccgctcggac ccgacggtgc caagccggga acgatgccgg
      181 gcggcgacga gggggcgggc ggcgggaggg gagttagaca gatttagctc aaccgctcca
      241 ggaccatggc catgccctgg ccgccgccga cgcacatggt ctccaggccg aactgcttgt
      301 cgtgccactg cagcgagttg atcagggtgg tggcgatcct ggcgccggtc atgccgaacg
      361 ggtggccgac cgcgatggcg ccgccgttga cgttgagccg gtcctcgtcc acgcccagtt
      421 cccgcgccga cgggatgacc tgggcggcga acgcctcgtt gatctcgacc aggtcgatgt
      481 ccgagatgga cagcccggcg cgcgcgagcg cctgccggga cgcctcgacc ggcccgaggc
      541 ccatgatctc cggggacagc ccggacaccc cggtggacac gatgcgcgcc agcggcgtca
      601 accccagctc ggcggccttg cggtcggaca tgatcaccag cgccgccgcg ccgtcgttga
      661 gcgggcagca gttgcccgcg gtgacccggc cgtcggggcg gaacaccggc ttgagggtgg
      721 ccgtcttctc gtaggtgatc ccggcgcgcg gaccgtcgtc ggtctccacg acgcgaccgt
      781 ccgggagggt caccggggtg atctccctgg cccagaagcc gctctcgatg gcctgctcgg
      841 cgcggttctg cgagcgaacg ccgaagtggt ccatctcctc gcgggtgatc cccttggcca
      901 gcgccaggtt ctccgcggtc tggcccatgg cgatgtaggc gttgggcacc cggccgtcga
      961 gccgggggtc gtgccactcg tcggcgccgg actcggcgac cgcggcggtg cgcgcctcgg
     1021 cctcggcgaa gatcgggttg tgcgtgtcgg gccaggagtc ggagctgccc ttggcgaagc
     1081 gcgagacggc ttccacgccc gcggagatga agacctcgcc ctcgcccgcc ttgatcgcgt
     1141 gcagcgccat ccgcgtggtc tgcagcgagg aggcgcagta gcgggtgacg gtgcaggcgg
     1201 gcagcgagtc gtagccgagc agcaccgcga cgacgcggcc catgttgttg ccctgctcgc
     1261 cgccgggcag gccgcagccg agcatgaggt cgtcgatgtc cgcggggtcg agcgcgggca
     1321 cccggtccag ggcggcgcgg accatctgcg cggtcaggtc gtcgggtcgg atgtcgacca
     1381 gcgaaccctt gcccgcccgg ccgatcggcg agcggacagc ggagacgatg actgcctctg
     1441 gcatggcggg tgctccttcg cggtaggtcg tccagcacga caccgctgag gttacccaca
     1501 ggtaactcac ccgtggagcc acgctgctca gccgggtgtc accgcactgt ggcacacccc
     1561 ggccaccgcg cacagtgggg cgaggatcac gctcgccgcc aggccgtacc cggcgccgtt
     1621 ggggtggaac cggtccgggc tgaacagctc gtccggcctg cgcgcgaagt gccgcgacac
     1681 cagcgtcatg ggcaccaccg ccgcgccgct gcccgccagc tcgcgggcct gggcccggcc
     1741 gagcgccagg ctccagcgct gggcgagcga gcgcagcggc tgcgggatcg ggcggaccgc
     1801 gcccaggtcg gggcaggtgc cgacgacgac cccggtaccg gccgcgacca gccgccggac
     1861 ctgctggccg aggagctccg cgcacgcgtt gacgccgagc cgggctgtca cgtcgttgcc
     1921 gccgaccatg accaccgcgg ccttcggcgg gtctaacagt gcgcgatcga tctgatcggc
     1981 gaggtgggta ctacgggaac cgacgacggc gtaggtcgtg agctgcaccg gtcggttgga
     2041 ctcttcagcc aatcccttcg cgagctgcac gccgggtaga gcttccggtg actccgcacc
     2101 cagccccgcg gcggtggagt caccgaagat tccgaaggta agagggtcgg tgacggttag
     2161 agggccagag ccgtcgggta ggtaaccgcc gtccgcgttg aaaggcaggt cccggggtac
     2221 accgatgacg ctgcgcgcct gccgggactg cgactgcagc agcgtgtacg ccgcgccgga
     2281 caggccgccc acggagcccg ccgcgacagc ggccacccag agcccacgga tccacaacat
     2341 cgcctgcccc cctccgacca aaggtgactg tcttagacct atcgccgtct tcgacctcct
     2401 ctttaccaaa cgcggcgatt acttcgccgc cgctggagcc gggatacgct cccccacgag
     2461 caggtcaacg acgcgaaccc ccaacgcgac cccacgaagg agcccctcgg tggagtacgt
     2521 cgagcacatc atcgatctcg tcggcgacac gcccctggtg aagctgaact cgctggccga
     2581 cgggctcgcc ccgaccgtgc tggcgaaggt cgagtacttc aacccgggcg gcagcgtcaa
     2641 ggaccggatc gcgctgcgca tggtcgaggc ggccgaggcc tccggtgagc tgcgccccgg
     2701 cggcacgatc gtcgagccca catcgggcaa caccggcgtc ggcctggccc tggtcgccca
     2761 gcgcaagggc tacaagtgcg tgttcgtctg cccggacaag gtcagcgagg acaagcgcaa
     2821 cgtgctcaag gcctacggcg ccgaggtcgt ggtctgcccg accgccgtcg ccccggagca
     2881 cccggactcc tactacaacg tgtccgaccg gctggtccgc gagatcgacg gcgcgtggaa
     2941 gcccaaccag tacgccaacc cggagaaccc ggagagccac taccgctcca ccggcccgga
     3001 gctgtggcag cagaccgacg gcaagatcac ccacttcgtg gcgggcgtcg gcaccggcgg
     3061 caccatctcc ggcaccggcc gctacctcaa ggaggtctcc ggcgggaagg tccaggtcat
     3121 cggcgccgac ccggagggct ccgtctactc gggcggcacc ggtcggccgt acctggtcga
     3181 gggcgtcggc gaggacttct ggccggagac ctacgaccgc tcggtggccg acgagatcat
     3241 cgcggtgtcg gactccgagt cgttcgaggt cacccgcagg ctcgcccgcg aggagggcct
     3301 gctggtcggc gggtcgtgcg ggatggcggc cgcggcggcg ctgcggctgg ccaagcggct
     3361 gggcccggac gacgtcgtgg tcgtgctgct gcccgacggc ggccgcggct acctgtccaa
     3421 ggtgttcaac gactcgtgga tggcgcagta cgggttcctg ccgcccgagc actccggtgc
     3481 caccgtcggt gacgtgctgc ggcgcaagag cgcctccggc accaccatcc ccgacttcgt
     3541 gcacgcccac ccgaccgaga cggtcgccga cgcggtggcc atcctgcgcg agttcggcgt
     3601 cagccagatg ccggtggtca acgccgagcc gccggtgatg gccgccgagg tggtcggcgc
     3661 ggtcaacgag cgcgacctgc tcgacgcgct gttcaccggc aaggccgcgc tggccgaccg
     3721 gctcgaccgg cacatgtccg gcccgctgcc caccatcggc gccggtgagc aggtgtcggt
     3781 ggcgatgaag gcgctgaccg acgccgacgg cgcgctggtg ctcgtggacg gcaagcccgc
     3841 gggtgtggtc accaggcaag atctcctggg cttcctggcc gggcggtgac gccctatggt
     3901 caccccgcat gccgcgaacc gcgcaccgat atcgcgtccg atagcgttac ccgcagagtt
     3961 gtctgtttcg ccaactgata gtccaggtca aaaggggtgg gaaacccgat gagtgctccc
     4021 caaccgccga accagccatg gcagggcggt cagccccagc agtggcctgg tcaacccggt
     4081 caggaccagc agccgtacgg ccagcagccg ggcgggtacc ccccgccgca gccgcactac
     4141 gcgccaccgc ccggtgacac caccggcgcc gacggcgtcg agcggacgca ggccatccgc
     4201 ccgggtcaga ccccgcccgg tggcgaggag gagggcgtcg accgcaccca ggtcgtgcgc
     4261 ccaggtcagg gtgacgcgac ccagatggtg ccgcccggct ccgtcccgca gtcgccgccg
     4321 tacgccccgc cgcccagcgc cgccgaccag gcgtcgcccc ccggtgggtt ccaccagccc
     4381 tacggccagc agccgccgcc ccagcagcag tacggccagc ccggtgggtt cggccagcag
     4441 cagggttacg gccagcagca gcccggcggc taccccggtc agccgggtgg cttcgcccag
     4501 cagcccggtc tcggcggcgc tcccggcgcg ggcggtcagg gccagaacac cggcatgatc
     4561 gcgctgatcg tgctcggcgc cgtcgcggtg ctcggcctga tcgcgctgat catgagcatc
     4621 tcgctgatgt ccaacctctc caccatcagc ggcctctgcg gcgacgtgag cgggctcggc
     4681 gggctggcct cgagctactg cccgagcggc ttcaacacgt tcctggcgtt cgtccagatc
     4741 gcgggcgcgg gcgtggcgat cgcgggcgcg gtcctgctgg cgctgaagaa gaacctgaac
     4801 atcgcccacc tgctcgtcgt gggcggcggt ggcgccctgg tggtcgccgc gatcatcaac
     4861 ggcgcgacct tcagcttcgt cggccagatc atgaccccgc tggtgttcgg cctgctcatc
     4921 gccggtgccg gtgcgctggc gttcttcccg cagaccaagg actacctgct cggcagctcc
     4981 ccgctcagct cgctcagcgg cggcggtggc cacggtggtc ctggtggtcc cggcagctcg
     5041 ggtggccccg gcgggttcgg ccagcagcag ggcttcggtc agccgcagca acagcagcag
     5101 tacggccagc cgggtgggta cggccagcag cagcccccgc agcagcaggg ctacggccag
     5161 cccggtgggt acggccagca gcagcagccg ggatacgggc agcagccccc gccgcccccg
     5221 cccggtggtg gtttcggcca gcagcccccc ggagggcagc agccaccgca gcagtggtga
     5281 cgaactgagt tgataggccc cggcaacccg ccggggccta tccgcgtctt tggggtcgat
     5341 aacacagacg cgagggggaa acatgaacta ccaggctcag ggctactacc cgcaattcca
     5401 gcagacgtcc ccgggaagcc ccggaacatc ggtgctcgcg ggcatcggcg cgctcggcat
     5461 cgccgccgga atgggcggcg cctcggcgta cttcctcgcc gaagtcccca ccgcgcgcga
     5521 catcttcgcc ctccccgcgg gcctccagtc cctgctcatc ggccgcatgg tgctcgccgc
     5581 cctggccttg atcggcgcca tcctgctgtt cacccgccgc cgagcaggcg tccccctggt
     5641 cgccctgacc gcggtggcga gcgtcgcgtc cctgcccctg gaacccctga tctccgaatt
     5701 gctccgcggc atcggaatca ccgtcagcgg ctacttcgaa gcactcctcg agttcaacga
     5761 cacctacaca atcctgttgg ccgtcggcgc cgcaaccggc ctgatcgcct tcctcttcgc
     5821 gatcctcccc gccaccagcc gctggctccg caccccgcgc tactgacccg cgttgctggg
     5881 cacccaggtg tcgcacactc cgccacctga cccgccgtac cggcgccgct tgctcaccgg
     5941 atccgcgccc accagccagc cttcaaccgc gaaccccaca accgcactca aacggggcca
     6001 accccagcca aacccgttgt cccccaacga aaacacgccc cacaacgcca gcctcgcgcg
     6061 cgcgaaaagc gagtgcccgg cccgcaccct ctccgggggg cgtccctggg ccagtctacc
     6121 gacacccccc gacagtcgat cttgaaacag gccccgcaga gatccacatg tggataactt
     6181 ctgtcaccca gaagcatgga tattgggggc gggacaaggg cagatccgca ggtcacagca
     6241 ccaaggggtc agcgtcgacg ccaagagcga ccaagtcgct cggcgagtga tcatccggcc
     6301 ggccagaatg tccacagtgg acacaacacc ccaccagggg gcgcgacggg cgggtgggtt
     6361 ctactacacc aacgcccgtt ctgggatcgc tcgatcagtg aaatattcct aatagtggga
     6421 acggtcccac atggtggtcg gatcggctgt tccccgtaac cttggggaca tggctgacga
     6481 gacgtcccgt tggggttttg agaccagggc gatccacgct gggcaggagc ccgatccgcg
     6541 caccggtgcg gtgatcgtgc cgatctacgc gacctccacc ttcgtccagg acggggttgg
     6601 cggggtgcgg gacggcgggt acgagtactc gcgcagcgcg aacccgacca ggacggcgct
     6661 ggagcaggcg ctggccgcgc tggagggggg caagcacggg ttggccttcg cctccgggtt
     6721 ggccgcctcc gatgtcgcgc tgcggtcgat gaccaggccg ggcgaccacg tcatcctcgg
     6781 caacgacgcg tacggcggga cgttccggct gctcgacaag gtcctcaccc agtggggcgt
     6841 cgagtacacc tcagtcgacc tggccgacct gaccgcgacc cgggccgcgc tgcgcccgac
     6901 caccaaggtc atctggtcgg agacgccgac caacccgctg ctcggggtcg ccgacatcgc
     6961 cgcgctggcc gccgtcgccg ccgagggtgg cgcgaagctg gtcatcgaca acaccttcgc
     7021 caccccgtac ctgcagtcgc cgctgggtct cggcgcggac gtggtgctgc actcgaccac
     7081 caagtacctc ggcggccact ccgatgtcgt cggcggcgcg ctgatcacct cggacgacga
     7141 gctgcgcgac aagttcacct tcctgcgcaa cgccgcgggc gcggtgccca gcccgttcga
     7201 cgcctggctg gtgctgcgcg gcgcgaagac gctggcgctg cgcatggagc ggcacagcga
     7261 caacgcggag cggatcgtcg aggtgctgct cgggcaccag aaggtcacca aggtctacta
     7321 ccccggtctg ccggagcacc ccgggcacga gatcgccgcc aagcagatgc gccgcttcgg
     7381 cgggatggtg tcgttctcgg tcgccggtgg cgaggaggcc gcgctcgcga tcgccgccag
     7441 gaccaagctg ttcctgctcg cggagtcgct cggcggcatc gagtcgctga tcgagcaccc
     7501 cggcaagatg acgcacgcca gcaccaccgg gtcgccgctg cagatcgcgg gcgacatcct
     7561 gcgcctgtcg gtcggcatcg aggacggcac cgacctggtc aacgacctgc tcaaggccct
     7621 cgactagcac cggccggacc cgctcgaacg ccgagaggcc cgatcccgcg aaccggggat
     7681 cgggcctctc gcgttgccaa gatcaggggc tggtctggtg gaaccgctcc acggcgctgc
     7741 ccgggttggt gcccaccgtc ggcgtgctcg gcgccgcggg caggtcggcc gggtcgacgc
     7801 agccgccgac gagctcgagg ccctggccgc gctgcacgaa ctcccccgcg ctggcgcacc
     7861 cggcgttgct caccgtgaag acggccaccc cggcgagcac cagtgccgct gcggcggcgc
     7921 cagccagcgg catcgtcctg cgtgaggtgg ccatggttct ccccgagtgg atatcgccct
     7981 ggggcgagcg tacccgcccg tccgccaccg cacctgagca gtagctgagt gtggcccccg
     8041 cccgggatcc ggacgggggc cacaccacgg gctctgggtt acaggttgcc ccggcggtcc
     8101 tgctcgcgct cgatcgcctc gaacagggcc ttgaagttgc ccttgccgaa gccgagggag
     8161 ccgtgccgct cgatcatctc gtagaagacc gtcggccggt cgccggtggg cttggtgaag
     8221 atctgcagca ggtagccgtc ctcgtcccgg tcgaccagga tggcgtgctc cttgagctgc
     8281 tcgatcggca cccgcacgtt gccgatgcgc tcgcgcagct ccgggtcctc gtagtaggag
     8341 tccggcacgt cgaggaactc gacaccggcg gcgcgcatgg cggtcacggt ggcgatgatg
     8401 tcgttggtgg ccagcgcgat gtgctggcag cctgggccgc cgtagaactc caggtactcg
     8461 tcgatctgcg acttcttctt cgcgatcgcg ggctcgttga gcgggaactt cacccggtgg
     8521 ttgccgttgg cgaccacctt gctcatcagc gccgagtact cggtggcgat gtcgtcgccg
     8581 acgaactccg ccatgttcac gaagcccatg acgcggttgt accagtcgac ccagtagtcc
     8641 atcttgccga gctcgacgtt gccgacgcag tggtcgacgg cctggaagat gcgcttcggg
     8701 gcaccctcgg gcttcttgta cgagcccgcc ttctcgacgt agccgggcag gtagacgccg
     8761 ttgtagcggg agcggtcgac cagggtgtgc cgggtcttgc cgtaggtcgc gatggcgccg
     8821 acgcggatgg tgccgtgctc gtcggtgacg tcgtgcgcct cttcgagcac gatcgcaccc
     8881 tgggcgcggg cgtgcgccag gcacttgtcc acgtcggtga cctcgagcgc gaggtcgacg
     8941 acgccgtcgc cgtgcgcgcg ctggtggtcg agcagcgggc tcttggggtc gacgccgccc
     9001 ttgatgacga agcgggccga gccggacttg agcacgtagg ccttgtggtc gcggttgccg
     9061 gtctcgggac cggagtacgc gacctgggtc atgccgaacg ccgactggta gaacagcgcg
     9121 gtctgggtgg cgttgccgac gacgaagacg acggcgtcca tggcccgcac cgggaacggg
     9181 tccttgctct cgtcgtactc cacgaggccg acgagctggc ggagctggtc gaagctcacc
     9241 tcgtccatgc cctggtcacc gcggttcagc gtgcccgtca tggcgttcct cctgcgttcg
     9301 cgtcctgcac ctgccccacg agcatgggta cttccgagca tcctgcgcaa cacttaggaa
     9361 gatcactgga caacatgact aggtattaac ggggcgtgtc tggcaaactg aacactctgc
     9421 tcagggaggg gctcgatgac cgaggagagt ccggggatcg acgacctgga cgcgcggctg
     9481 ctgttgctgc tcaccgacga gccgcgactg ggggtgctgg agtgctcgcg caggctcggc
     9541 gtcgcgcgcg gcacggtgca ggcgcggatg gaccggctcg accggcgggg ggtgctgacc
     9601 ggcttcccgc ccgccgtcga cctcgccgcg atgggctacg gcctcaccgc gttcgccgtc
     9661 ttggagatcg cccagggcaa gcgcggggaa gtcgccaccc ggctgcacgc catccccgag
     9721 gtgtgcgagg tgcacgccac caccggcgag ggcgacctgc tggtgcggat ggtcgcccag
     9781 aacaacgccg acctgcagcg ggtgatcgac cgggtggtca acgtcgagtg ggtgcgccgc
     9841 acatcgacct cgatcgcgct gtccacgccg atcccgcccc gggtccggcc gctgctggaa
     9901 cgcgcggtcc ggcagtccgg ctgagtggcg gacccggggg cgcgcgtgcg ctcggtcagg
     9961 ccgcgggacg ccctcgtcga cgtgtgcgtg gcggttctcg ctagtcgacc aggggttcgt
    10021 gcacggtgcc gatgcggtgc agggtgcggt gctcggcgga ggtgttgccc gccaggtcgt
    10081 cgtcgatccg gcggccgtcg ccgtggtagc ggctgctctc cctggcgtgc cggaggttgc
    10141 cggagatcat gtggccgacc tcgaccagga accgggcgac gtcgtcgcgg tggcgcagcg
    10201 gaccggtggc gacccggtcg cgggtggcga tgaaccgctc ctcggtcgcc acggcgcggg
    10261 cggcgatggc gtcgagcgcc tcctgcagcg gcgcgccttg tcctaagagg acccacacgg
    10321 cgttgatctt ctcgccctcc tcgatctcct tggcgaagga gtagaggtcg ttgaccagca
    10381 cccagtggtc gatggcgagg gtacaagcct tgtgcaccaa cgggtcttgg ctggccagcc
    10441 cgtcgaggtc gatgccgagc gcccactcgg cgagggccag gatccagaac ccgtaggcgt
    10501 tcacccggcg gctggagccg aggtaggcgt ccaggtcgtc gaactcctcg acggtgttct
    10561 ggttcgcgtt gtcgatcacc acggtcttgc cgacgtcgat gaggcgttgc cgcagcgagc
    10621 cgctgtcggg cagcagcagg gcgtgcacgt cgctgagcag cctggccagc ggggtcgcgc
    10681 cgccgggggc cgcctcgacg gccgcgcaca actgccgggc gagcaggtcc cgcgcgggtt
    10741 gctcgcgcag ccacggcgcg gagaaggcgt cgtcgagcag cgcggcggcg ttcatccaca
    10801 gctgttgcgc gaagaaccgg tccggcctgg tgtgcggcat gcacagggcg ccccagcggt
    10861 gcaggtcctg gcggaggtac cggtcggtga tcggactgtc ctgttcggac tcgccgaagt
    10921 agtcgaccag gtgcggccgc agccaggcca gcacccgcgg cgcggtggcg gtgaactccg
    10981 ggtgcagcgc gagcggggac cgggtgggca gcgcgggcag ccggtaggtc atcccgtaac
    11041 ggagtccggc gccgggatgg gaagaatttt tcacaccaac tcctccattt tattgttcaa
    11101 ttgtaaacgc ggtggattgt ttcgctccat ccggctcatg cggatgccgc agcggttcac
    11161 ctgtgcggac gcacggtcgt cacggtgtgc acggcgtcga tgctccacac cggtgatctt
    11221 gaccggtacc cgccgaacgg gttcaaccgg ggcgtggtcg tcgcttcctt aatcacgaac
    11281 gggtgacggc cacatcaccc gagtgtgaat ggctttcacc tgtgcggcag cgctcccggc
    11341 acccagtgcg gccgggcttg cgccatgcgg gggaaggttc ggccggagat cacccgaaaa
    11401 gatcaccgtc ggtcgtgcag gtgcacggga tcattcaagg agcgccatcg gccgtcgacg
    11461 gaggaagcac caggcatggg tcccggtacc gagcagctgc ttgccaccag ccgggccgcg
    11521 gtactgcctg cgctgcgtgc cgccgtcgac tcgctgccgc ctgccatgcg gcggatagcg
    11581 tgctaccact tcggatgggt cgacgcctgc ggcgccccga tcgaggcgga tagcggcaag
    11641 atggtccgct ccgcgctgac cctgttgtcg gcggaggcgg tcggcggcga cccggcggac
    11701 gccgtcccag cggcggtggc gatcgaactc gtgcacaact tctcactgct gcacgacgac
    11761 atcatggacg gcgaccggac caggcggcac cggggcacgg cgtgggcggt gttcggcgtc
    11821 ccggccgccc tgctcgctgg cgacgccttg tgggcactgg cgttgcgggt gctcgccgcc
    11881 ggaccgcacg cggaccgagc gcttcccttg ctcaccgagg ctttgtggcg gctcatggac
    11941 ggccagagcg ccgacgccga cttcccgcac cggcactcgg tgaccctcgc cgagtgcgag
    12001 gccatggccg cgggcaagac cggcgccgtc atggcctgcg ccaccgccct cggcgccctc
    12061 ttcggcggcg ccacccccga ccaactcgcc ctcctgcgcg acatgggcga acacctcggc
    12121 ctggccttcc aactggtcga cgacctgctc ggcatctggg gcgaccccac aacaacgggc
    12181 aaacccggcg ccgacctggt ccaccgcaag cgctccctgc ccgtggtcgc cgccctcact
    12241 tcgaacaccc ccgcgggcgc cgaactggcc accctctacc tggccaccga ccaccccatg
    12301 accaccccgg aacaaacccg cgccgccacc ctcatcacca ccgcgggcgg ccgcacctgg
    12361 gccaccaccc aggccgaact ccacctggcc caagccacca ctgccctgcg ccgcaccaac
    12421 ccacccgccc ccgccctggc caacctcctg gccctggccg accacttcgc ccaccgcacc
    12481 agctgatccc acgatcgtcc acacaggact cttttgcctc gcaacggctt caatggcctc
    12541 caatggcgcc aatagtccac atcggacttt cacctgcgag agcaaacccc gctgctcgcc
    12601 gcacccggcc ccaccagccg ccacaaccgg aggccgcccc cgcaaacccc ggcccccacc
    12661 ctgtcccggg gggcgtcccc aggcccagtg taccgggccc ctatcgcccg aaggggtgac
    12721 ggcgaaaacc tgtggacaac tggggggcct gtggacaact tgatctgggg agatggtcgg
    12781 cggcgagaag tgggctgggg gaaatcaccc ggtggagggg ctccggggag gggcggcctg
    12841 ctggtcgaaa cgcaagggcg accagggttc ggtgcacgtg ggcggacgct ggcccggggt
    12901 gcgggagagg cgcgggcaga acgaagccca gctcgcgcga caccgggcgg ccagggcggg
    12961 catagggccg agggttgggc gcctacggct cgcggcaggg cacgcccagg aggggcgcgc
    13021 gcccggtgag ggcacgagac cacagcgccg cgggtgtgca ggaagcaccc gaagcgccag
    13081 gcgcggcagg aaccgcccga aggtccgcgc accacaggaa cggcccgaag gtccgggcgc
    13141 ggcaggaacc gcctgaggtg ccgggcgcag caggaaccgc cgaagtgccg ccgggcggcg
    13201 ggcggcgggc ggcgggcgac ccaggaaacc caggaagagc tagctggtcg tctgtggcag
    13261 cggcaggttc ttggccgttg gcgcgttggc ggtggtttcg tccagttcgg actcggcttc
    13321 gaggggttgg aggagttggg agctctgcgt cagcagctcc gaggtgcccc gcaaccgccc
    13381 ggccaactgc tcgcgcaggg ctgtcagccg ctccacctgg ctggtggccg tggcgatgcg
    13441 cttgtcggct tcgtcggtcg cggcctggac gagcgcggcg gcctcggcgg tggccgtggc
    13501 gcgggcggtg gtgacctcgg tgtcgaggtc ggagcggcgg gtggcgagtt cctgctggaa
    13561 ggcctgctcg agccgctggc ggtcgcgttc ggcttggtcg tcggtggtgc gctggcgggc
    13621 cgtggcggcg gtggtcatgt cgtcgacctt ggtgcgggtc tcggccatga actcggcgtg
    13681 cgcggtgtgc agttcggcgt ggcgcttctc ggcgtcggcc atcagggcgc ggtagcggtc
    13741 gcgcagggcc acggaggcgg cctcggcggc ggaccacgcg gtgtcggcgg cggcctcggc
    13801 gcgggcggtg atctccctgg cctgcgcctc ggcggtggcg atggtgcggg cggcccgctc
    13861 ggcggcgttg ggggccgagg acgcggcggc ggcgttgccg atcttgtcga ggcgctcggt
    13921 gagggcggcg atctcgcggc gggccagctg gagctggccg tcgacctcct cggcgcgcgc
    13981 cagtgcctcg tcccgctcgg cggtgatcgc ggcgtgctgg tcggcgaggg tgccgaggta
    14041 gcgcttcacc tgggtccggt cgtagccgtg ccgcgacacg ccgaactcgg ggtgatcctg
    14101 ctgggggccc atggcgacga ccgtacccgc gaggccaccg gcggcaacat gaaggccgct
    14161 cgaccgggtg acacatcacc ccgcagaggg ggtccaacag ccccgggatg ccgcagcggc
    14221 acctgcctgc cgggagccgt tgaccaccgg gaccccctca gccagccagc gacaccggac
    14281 cgggcacgaa ccccgggtcg acctgctcgg ccaggtcgcg gcccgcgcgc ccgttggccc
    14341 acgcggaagc gttgcgcagg tggaactcca cggtctgccg gtggaacttc ggccagtcct
    14401 gctcgacccc gtcgaccagg gcgcgcatcg cgcgcaacgc ctcgcggttg gccggttcga
    14461 gccgctcgac cggccggatg tcaccgcgct cggcggcccg gacgtggtcg gagcggccga
    14521 tccaggtgag caggtcggca ccgacgtgct ggcgcaggaa cgccacgtca tcggcatcga
    14581 tgaccttgtt gccgaccacc gcgacccgca cgtcgaagtc ccgcgcgtag tccaggtact
    14641 gccggtagac gccgacgctg cgcagcgtgg gctcgcacac caggaaggtg acatcgaatc
    14701 gggtgaacag gccggaagcg aatgaatcgg cgcccgcggt catgtcgacc accgcgtact
    14761 cgcctgcgcc gtcgaccatg tggttgagca gcagctcgac cgcgccgacc ttcgagtggt
    14821 agcaggacac cccgaggtcg gactcggcga acgggccggt cgcggccagc cggacgccgt
    14881 cgacccggcg gacgaaccgg gcgtagagcg ggttgtcgtc gtcgatgccg atcagccggg
    14941 agccccggcc gggcggggtc gtcttgatca tgtcggcggc cgagtgcacc agcgggttgt
    15001 ccccgcgcag gtggtccttg atggccgtca ggtgctcacc gagggtgggc tgggtgtggt
    15061 cgtcggcggc gccgagggcg gcggcgaggt gctggttgat gtcggcgtcg atgccgagca
    15121 gcggcggtgt gggggtctct gcggccaggt ggcgcaggaa cagcgacgcc agcgtggtct
    15181 tgccgctgcc gcccttgcct acgaaggcga tcttcacggg ggtctccggt ggtgctggtg
    15241 gatcggaccc cactactggt atcggttatc attatccaaa gcaagcggga tcacccgaat
    15301 gtgatcagct cggttgggcg atctgcgcgt tgggcattgc ccggaacgcg tcgagcaccg
    15361 ccgggtcctg caaggcgagc cattccacga cctccgagta ggtggcgcac accgtctcgg
    15421 gtttcgcgca caccgaaccc atgaacttct ccgtcgccgc ggtgaacgcg ccgccggacc
    15481 agttgttgaa gtggttgccc accaccatcg gcgcccggtt cccgtcgaac gcggcctggt
    15541 aggcgcgttc ataggtctcc tggacgacgg cggtgaactc gggcgcccga ctcgggtcgt
    15601 ccttcgcctt gttcagcagg taccagaagt tgtagtccat catgattgtc ttcttgtact
    15661 tcagccctgg cacccgaacc gagggcatgg caaattccca caccccgtgc tgtgtcgtgg
    15721 gccaggcgag tccgtcgctg acctggctgg tgtcgtaggt catcccgcgg ctggcgagca
    15781 ccggcagcag cacgtcgaac tggccctcca ggcacggtgt ccgaccgccc ttgatggcct
    15841 tcgggtcgac cttgaggccc tgcgccctgc cccggtccac gaaggcgaag aactggtcca
    15901 gctcggagtt ccactgcgcg gcgtcccacc ggccgacgcc gggctcggcg ccctggcaga
    15961 agtgcccgtt gtagtgggtg ccgacctcgt tgccctggtc gacggcggcg ttgaggtcgc
    16021 cgatgagcgc ctggacgtcc tgctgcgtgc cgccgaaccc gatcgacgcg cggccgggtt
    16081 tgtggccggg gccggtgtac tcggctttct gctcgtcggt cagcaggtag ataccggaca
    16141 agaagcccga gaaatgcgcg ttcacacttc tcgccaatgg caagaacttc tgccagtgct
    16201 cgtgcgagcc cgcgccgtcg aaggagaaca ggacgaactg cggtggtttc tcacccgggt
    16261 tcagcttccg catccacttc ggcggaccgg cggatgcctg cgggtgtggt tccgcttcga
    16321 gcacgcgcgt ttgcggttgc ggacgcacgg taccgacgac gaccagaatg acgaatgcca
    16381 acgccagtgc caccccgacg gcgacgatct cccaacgcct tctcgttgtc atccgcgttc
    16441 cctccccggt tgtccgccgc tccccaccgg aatagacgcg cgacgggatg actcgttgcc
    16501 accggtgatt cgccgtcccc cggacgtgac cgatcgcccc ggttcaggga cacccagccg
    16561 gggggacgac ctcaggcggg tacggcgatg accacccggt tggactcgta gccgtccgac
    16621 ccgccgaccc actggccacc gcaggtgacc aggacgaccc ggtgcggacc ggtctgcccg
    16681 aagaactcct cggccctggc aggcaggtcg tgcttgctga ccgtctccac ccgggtcacc
    16741 cggtagcgcc actgggtgcc cttgtcgtcg acgaccgaga cgaggtcacc gacccgcgag
    16801 ctccacagct cggagaacgg ccccgtggcg cccttccagt tgacgtgccc ggcgaacacg
    16861 gaggcgcccg tgggcgcgtc gagccccgcg ccccaccagg tggcctcctt gaccccgctc
    16921 gggaccggca gcgtggcgtc cgggccgagt tccttgcgca ccagggtcgc ggtgccgccc
    16981 ttggcgagcc gcagcgtgcc ggggcgctgc ccggccaccg gctggcgcgg cggcgggggt
    17041 gcttcggcgg cgggcggcgt ggtggtcgag gtcggtggtg gcgcgctcgg ctccaccgac
    17101 ggcgcgggtt cggccggctt cggcttgatc tgggaccgca gaccggccag tgccgcgtcg
    17161 ctctcgttgg cggccttgcg gatggcggtg agctgcagac ccggttgggc gggcagcggc
    17221 aacccctgga ccggggtcgg cgacgcgaag gtcaacccgc agaccaggag cacgagcacg
    17281 cccgccccac ccgcgacggc gggtggggcg agcgtcgagc tacggcgagc catgcccggt
    17341 cagtgccccc agtccttgcg catccggcgg ccgaccacga tcggcccgcg gcccttgcgc
    17401 accagggcgg tgccggcacc ggcggcgaac agcagcagcg cgccgagggc gaccagcagc
    17461 ccggtggacg ggccaccggc gtcgagcacg gcggcggcgt tggccgggcc gtcaccggcc
    17521 gggatggtct gcgggacggt gggcacgttc ggcttgttga ccagccgcag ttccaccgtc
    17581 ttgcccggtt cgagcttccc gcacgcggac ggcgggttgt tcgggtcgta ggactgctcg
    17641 tagcccggcg gcgccgcgac ctcggtgacg cagacctcct gcggggtgcg caggttgggc
    17701 acggtggcct tgccgtcggc gccggtcacc acgaccagcg gcttgccgtc cgcgccgacc
    17761 aggggtttgc cgtcctggtc gaccgcgggg gtcgtcttgt cggcgccggt gaccttcagc
    17821 gacaccgagg cgatgccctg cccggtcttc tcgtcgacct tggccaccgc gacctggccg
    17881 ggcgcggtga cggcggtggt gtcggccgcc gccttgagct ccttctcgcc gccggtggac
    17941 accacgctct gcgtgccgtc ctcgacggcg tgctggacga ccggctggtc ggccggggcg
    18001 agcagcgaga tcgacaccga tggcttcggc ccggtcggca cgacctccag cgcgatgggg
    18061 ccgccgttgt ccttggtggt cgcggtcagc tcggtcttgc cacccgaggt ggcgtcggtc
    18121 agcacgacct tgaccgggac cttgccgacg ccgctgccgc ccgcgccgcg cacctcgatg
    18181 ggccaggtgt ccggggtgcc gatgacctgc ggcttggtcg gcttggtcag cagcggggtc
    18241 cacgggccgt ggttggcggt ggcgtcggcc ctgagcttgg cgacggtccg catcgcgccg
    18301 gggagcttct cctccagcgc acgctcgtgg aagggaacgt tgtaggcgat cgtgcggaat
    18361 ccgttggtgg ccgggtcgag gtcggccggg gtgcgcgggg ccgccgtcca ctggtgcagc
    18421 aggtgcgcca gggcggccga ctcggcggtg tccttggtgt cggcgtagcg cagcagcagg
    18481 taggagatgt cggcggcgtg gaccgggtcg agcgcggcgc cgtacttggt cttgagcacg
    18541 tcactgggct ggtagacctc gttggtgtcg ggctccttga acgcgaactt gacgcaccag
    18601 acctgcttgc cgttcacgag gtaggacccg agccagtcct cggtggcttc cctcggcggg
    18661 tccttgtagg gctgcagggc caccccgatg ccggggccct tcttgtactc ggcggcggcg
    18721 ggtggggcgc cgacgacgag taacgccgcc gacagggtgg ccaccgtcgc caccgcagag
    18781 ctcagccggg caccgagtgt ggatcgccgc atgggtcgtc ggctccttgc cgcgccgggg
    18841 cagcgcacgg ccgtcggcgc ttgaagtgcg ggactttcct ggcggtgcgg cccgccaagg
    18901 gagacggttg gggaccgggg ggcgcacctc gtgcgagcct gctaggcggg cggggggccg
    18961 ggcaatccgc ccaacgggtg gagatgatca tggttaccct gcggcgttcc cccaggtcgg
    19021 tgccaggtcc ggaccagggt gggggtatcg gacggcgtag ggtgcacctc ggccggtcac
    19081 gcacggtgtg gtgcgcggga atcgacggtg cccgcactgc gttgctccga atgtgggtaa
    19141 agtgggtttt acccagcggg aaccggtcgg ccgggtcgat cgttgaccgt cagcaggcgc
    19201 catccaggcc caggaggatc aggtgcgttc taccagcaac cccgcgttcc gtaacctgcc
    19261 gcagggcggt tacgcgggct tccagcccca ggcccagggc taccaggacc agggctaccc
    19321 gcccgggtac ggcagcccga gcgcgccagc gggcaccggc gaccggccga tgaccgtcga
    19381 cgacgtcgtc accaagaccg cggccaccct cggcgtcgcc ctcgtggtgg gcatcatcac
    19441 cgcggtgctc gtgctcggca aggacatcag cccgtacccg ccgatgatca tcggcgccat
    19501 cgtcggcctg gtcatctcgc tcgtcatcat cttcaagaag accccgagcc ccgcgctcgt
    19561 gctgacctac tcggcggccg agggcctgtt cctcggtgcc atcaccggtg tcttcgagat
    19621 gttcgtcccc ggcatcgcct tccaggcgat cctgggcacc gcgctggtgt tcatcaccat
    19681 gctggtggtc tacaagaccg gcgccatcaa ggtcaccccg aagctgacca agtggatcat
    19741 cggtgccacc gtcggcgccg ctggcctgat gctggtcaac ctggtgctct cgatgttcgg
    19801 cgtgaacatg ggaatccgcg acgccggacc gctgggcatc ggcatcagcc tgctgttcat
    19861 cggcatcgcc gcgttcaact tcctgctcga cttcgacatg gccgaccaga tgatccgctc
    19921 cggcaccccg tcgaagttcg cctggtacgt cgccttcggc ctgatgacca ccctggtctg
    19981 gctgtacctg gagatcctgc gcctgctcta catgctgcag agcagcgact gatcgcactg
    20041 actcgtgagg ggcgcccgac cggctggttg ggcgcccctt ccgtttggcc ttagagtcga
    20101 tctcgtgcgc gcactcatct cgtggctgct gtgcctggcc ggggtcgccg tggtcgggtt
    20161 cggggcgttc cggccgtggt acgagggccg ggcgggcaac acgctgccgt tgtcggacct
    20221 gttcagcggg gtcagccggg agagcgcgcc ggtgttgggg tcgttgacgc tgccgttggc
    20281 catcggggtg ctgctggcgg tggtggggat gttccgcgcc aaggggatcc tgcagctggg
    20341 tggggtcatc ctggcggcga cgatgatcgg gtgggtcgtg caggcgcgcg aggtcgtgga
    20401 cctgggtgac ctgcaactgg gggcgtggaa cgcgctgttc ggcagcctgc tggtgctggc
    20461 ctccgggatc atgcgccccg ggcgggtctg acggctcagc cgagcaccct ggccacgcgg
    20521 cgcatcaggc cggggaagaa ccgggcgcct gcgcgggcga gcttggcctc cggggtgacc
    20581 gcgacgaccg gggtgccgcg ttcgacggcg cggacgatct cctcggcgac ccggtccggg
    20641 gtgaacccgc ggcgcgcgta ggccttggtg gcctgctgcc gcatccgttg ctgcccgagg
    20701 tcatcggtgc cggtgaacgt cgtcgtgttg gtgatgtcgg tggccaccac acccgggcag
    20761 atcgcggtga cgccgatgcc gtggtcggcg aactcggcgc gaacgcagtc agacagtgct
    20821 aacaccgccg ctttgcttgc tgcgtaagcg gagagggagc ggctgggggt gtacgcggcc
    20881 gccgacgaga tgttgacgat gtggccgccc tcccccgctt cagccatcag cgcgccgaac
    20941 tcgcggcagc cgttgacgac gccgagcagg ttgacgtccg tgacgcggcg ccagtcctgc
    21001 gcggtggtgg ccaggaacgg ccccgccatg ccgatcccgg cgttgttgac cacgatgtcg
    21061 ggggcgccgt gctggtcggt gatgtcctcg gcgaacgcgc gaacggcatc ggcgtcggac
    21121 acgtcaaccg ggtgcggata ggcggctggc ccgatctcgg cggcggtgcg gcgtgcggcc
    21181 tctatgtcga tgtcagcgac cacgacctcc gctcccctag cggcgaacgc gagcgcggta
    21241 gccctaccga tgcccttgcc cgccccggtg acgacgacca ggcggttggt gaagccctcg
    21301 tcccggcccg cacgggcgcg ttgcaggctg cgggtcatcg gggcgccgga gacgtgctcg
    21361 acgaagtcct cgaccacgcg ggccagcgcc tcggggtgcg acagcggcac ccagtgcccg
    21421 gcgacgagcc tgcgccgcca cagccggggg atccagcgct ccaggtcctc ggcgagggcc
    21481 gcggtgacga accggtccct ggtcgggagc acgacctgaa tcggcacctc ggcggggctg
    21541 ggcgctgggc gggaccggcg gctgagcatg ttggcccggt acagccgcac gccgttggcc
    21601 gcgtcggtgc cgatcgtcgg cgcgggggtg gcctcgacgc cctccatgcg gcgcaggagg
    21661 tggccccagc ggggtccgac gaccgtgcgc caagcgaggc cgggcaggac ggggatgtgg
    21721 aacagcgcga tgtaccagga gtgggtgagc tgcgcgacga cctggcgcag gttcgccggg
    21781 gtcggccggg tgacccggcg gcgcacccac tgcccgacgt ggtccaggtt cgggccggag
    21841 accgaggtga acgacgcgat cctggccttg gcgcgcggcg cggtgaccgc cgcccaggcc
    21901 tggatcgagc cccagtcgtg cgcgacgacg tgcacgggcc ggttcgggct gaccgcgtcg
    21961 gcgacggcga acaggtcctc ggccagcagt tcggtgcggt actcagcggt cttgcgcggg
    22021 gccgtggagg ctcccgcgcc gcgcacgtcg tagcggacca cgtggtagtc gccgatcagg
    22081 cgctcggcga ggccgtccca gaggcggtgc gtgtcgggga agccgtgcac cagcaggatc
    22141 gtcggcgagg cggggtcgcc ctcgctgaac acagccagct cgacgccgtc gttgcttacg
    22201 gtgcggcggc gcggcccagt ggcgggcagt gggcgcggtt cgctgaccat ggcggctcct
    22261 gccctaccgg gttacgcgac aatgacgaac gttacaatcg ccattgtcac agtgcaaggg
    22321 tgtcactcgg cccgctccct ggcccgctcg gccagcgcga tcagccggtc cccgagcacc
    22381 tcggggatga cccggcgcgc ggagcggtcc accgccgcgc ccaccgcgga catcaccagc
    22441 gggtgcagcc gggagatgac gtcggcgaag tgcggcagct cctcgc
//
