LOCUS       NZ_JAMYDW010000018     10173 bp    DNA     linear   CON 24-SEP-2024
DEFINITION  Bacillus subtilis strain X0416 contig18, whole genome shotgun
            sequence.
ACCESSION   NZ_JAMYDW010000018
VERSION     NZ_JAMYDW010000018.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 10173)
  AUTHORS   Xue,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-JUN-2022) Food Academy, Sichuan Agricultural
            University, Xinkang Road No. 48, Ya'an, Sichuan 625000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.0.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024128815.1-RS_2024_09_24
            Annotation Date                   :: 09/24/2024 05:23:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,267
            CDSs (total)                      :: 4,141
            Genes (coding)                    :: 4,000
            CDSs (with protein)               :: 4,000
            Genes (RNA)                       :: 126
            rRNAs                             :: 12, 14, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 3, 14, 10 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 75 of 141
            Pseudo Genes (incomplete)         :: 74 of 141
            Pseudo Genes (internal stop)      :: 17 of 141
            Pseudo Genes (multiple problems)  :: 21 of 141
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:26:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 10173
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAMYDW010000018.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            <1..3773
                     /gene="ppsC"
                     /locus_tag="NHM07_RS20740"
                     /old_locus_tag="NHM07_20740"
                     /pseudo=""
     source          1..10173
                     /collection_date="2021-12-11T16:00:00Z"
                     /db_xref="taxon:1423"
                     /geo_loc_name="China: Yaan"
                     /isolation_source="spice"
                     /mol_type="genomic DNA"
                     /organism="Bacillus subtilis"
                     /strain="X0416"
                     /submitter_seqid="contig18"
     region          1..10173
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..10173
                     /SMILES="NC(C(C)C)C(=O)N1C(CCC1)C(=O)NC(CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10173
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<4:>10173](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <5..>10173
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             <5..3773
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (211-604). E-value:
                     3.4e-115. Score: 376.9. Matches aSDomain:
                     nrpspksdomains_NHM07_RS20740_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (709-777). E-value: 2.7e-24. Score:
                     77.2. Matches aSDomain: nrpspksdomains_NHM07_RS20740_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (787-1089). E-value:
                     7e-167. Score: 548.4. Matches aSDomain:
                     nrpspksdomains_NHM07_RS20740_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1095-1249). E-value: 8.2e-53.
                     Score: 170.3. Matches aSDomain:
                     nrpspksdomains_NHM07_RS20740_TIGR01720.1"
                     /codon_start=3
                     /gene="ppsC"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389714.1"
                     /locus_tag="NHM07_RS20740"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="NHM07_20740"
                     /product="plipastatin non-ribosomal peptide synthetase
                     PpsC"
                     /pseudo=""
                     /sec_met_domain="AMP-binding (E-value: 8.4e-123, bitscore:
                     397.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.9e-16, bitscore:
                     47.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.1e-79, bitscore:
                     253.8, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="TAFLSRLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLALRTRPE
                     GGKPFVQYLQEVRETALEAFEHQDYPFEELVDKLELTRDMSRNPLFDVMFVLQNMDQES
                     LELDELCLKPAANNGHQTSKFDLTLYAQEQPHGLLTFQMEFSTDLYKKKTIEKWLQYFI
                     NMLLSIIKDNKAALGTINILNEDETHYLIHELNRTKIDYPRNETISRLFEMQAEQTPNA
                     VAIVSDTQVFTYEDLNSWANQIASVLQIKGVGPDSVVALLTGRTPELIAGMLGILKAGG
                     AYLPIASDLPVERIAYMLSDSGAALLLQSEKTEKQLLDIECEQIIIEDIQKQGETKNID
                     SSAGPHSLAYIIYTSGSTGKPKGVMIEQRSVIRLVKNSNYITFTPEDRLLMTSSIGFDV
                     GSFEIFGPLLNGAALHLSDQQTFLDSHQLKRYIEHQGITTIWLTSSLFNHLTEQNEQTF
                     SQLKHLIIGGEALSPSHVNRIRNVCPEVSIWNGYGPTENTTFSTCLHIQKTYELSIPIG
                     RPVGNSTAYILNQWRVLQPVGAVGELCVGGDGVARGYLGRPDLTKEKFVPHPFAPGDRL
                     YRTGDLARWLPDGTIEYVGRIDDQVKVRGYRVELGEIESALRQIDGVKEAAVLARTAQT
                     GSKELFGYISVKAGTNAEQVRSLLARSLPNYMIPAYIIEMETLPLTSNGKLNRKALPEP
                     NFTSKQTYAPPRNDLEDQLVLIWQEVLGIQRIGIEDSFFELGGDSIKALQVSARLGRYG
                     LSLQVSDLFRHPKIKDLSPFIRKSERIIEQGPVQGDVPWTPVQQWFFSQDIEERHHFNQ
                     SVMLFHSGRLSENALRPALKKLAEHHDALRMVYRNDGRRWIQINQGIHESQLYSLRTSD
                     LSQSESGWETQIKQEVADLQQSINLQEGPLLHAALFKTLTGDYLFLAIHHLVVDGVSWR
                     ILLEDLSAGYQQAASGQTIQLPPKTDSYQEYARRIQEYAQSSKLIREEAYWRSVEEQQA
                     AELPYEIPHHVNIDSSKRDSLSFSLTEADTAVLLQNVNYAYGTDTQDILLTAASLAICE
                     WTGGSKLRIAMEGHGREHILPELDISRTVGWFTSMYPALISFENHRDELGTAVKTVKDT
                     LGRIPNKGVGYGMLKYLTHPENKSITFSKTPEISFNYLGQFNDIERQDTFRPSSLGSGK
                     DITHTWKREQIIEMSAMAADKKLHFNLSYPPACFHKNTMEQLINRIEHFLLDIMKHCAG
                     QQKAEKTLSDFSSQSLTAEDLDSISSLVEEL"
     CDS_motif       39..128
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20740_0001"
                     /evalue="1.40E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="41"
                     /protein_start="11"
                     /score="49.6"
                     /tool="antismash"
                     /translation="DIIVGSPIAGRPHKDLEPILGMFVNTLALR"
     CDS_motif       177..296
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20740_0002"
                     /evalue="9.00E-23"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="97"
                     /protein_start="57"
                     /score="72.8"
                     /tool="antismash"
                     /translation="RETALEAFEHQDYPFEELVDKLELTRDMSRNPLFDVMFVL"
     aSDomain        639..1817
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NHM07_RS20740_AMP-binding.1"
                     /evalue="3.40E-115"
                     /label="NHM07_RS20740_AMP-binding.1"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="604"
                     /protein_start="211"
                     /score="376.9"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEMQAEQTPNAVAIVSDTQVFTYEDLNSWANQIASVLQIKGVGPD
                     SVVALLTGRTPELIAGMLGILKAGGAYLPIASDLPVERIAYMLSDSGAALLLQSEKTEK
                     QLLDIECEQIIIEDIQKQGETKNIDSSAGPHSLAYIIYTSGSTGKPKGVMIEQRSVIRL
                     VKNSNYITFTPEDRLLMTSSIGFDVGSFEIFGPLLNGAALHLSDQQTFLDSHQLKRYIE
                     HQGITTIWLTSSLFNHLTEQNEQTFSQLKHLIIGGEALSPSHVNRIRNVCPEVSIWNGY
                     GPTENTTFSTCLHIQKTYELSIPIGRPVGNSTAYILNQWRVLQPVGAVGELCVGGDGVA
                     RGYLGRPDLTKEKFVPHPFAPGDRLYRTGDLARWLPDGTIEYVGRIDDQVKVR"
     aSModule        639..3752
                     /complete
                     /domains="nrpspksdomains_NHM07_RS20740_AMP-binding.1"
                     /domains="nrpspksdomains_NHM07_RS20740_PCP.1"
                     /domains="nrpspksdomains_NHM07_RS20740_Epimerization.1"
                     /domains="nrpspksdomains_NHM07_RS20740_TIGR01720.1"
                     /locus_tags="NHM07_RS20740"
                     /monomer_pairings="Val -> D-Val"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       825..863
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20740_0003"
                     /evalue="1.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="286"
                     /protein_start="273"
                     /score="14.9"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPI"
     CDS_motif       1050..1106
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20740_0004"
                     /evalue="1.10E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="367"
                     /protein_start="348"
                     /score="33.3"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVMIE"
     CDS_motif       1611..1700
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20740_0005"
                     /evalue="4.40E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="565"
                     /protein_start="535"
                     /score="57.3"
                     /tool="antismash"
                     /translation="PVGAVGELCVGGDGVARGYLGRPDLTKEKF"
     CDS_motif       1782..1847
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20740_0006"
                     /evalue="1.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="614"
                     /protein_start="592"
                     /score="39.0"
                     /tool="antismash"
                     /translation="YVGRIDDQVKVRGYRVELGEIE"
     aSDomain        2133..2336
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NHM07_RS20740_PCP.1"
                     /evalue="2.70E-24"
                     /label="NHM07_RS20740_PCP.1"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="777"
                     /protein_start="709"
                     /score="77.2"
                     /tool="antismash"
                     /translation="EDQLVLIWQEVLGIQRIGIEDSFFELGGDSIKALQVSARLGRYGL
                     SLQVSDLFRHPKIKDLSPFIRKS"
     aSDomain        2367..3272
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NHM07_RS20740_Epimerization.1"
                     /evalue="7.00E-167"
                     /label="NHM07_RS20740_Epimerization.1"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="1089"
                     /protein_start="787"
                     /score="548.4"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDG"
                     /tool="antismash"
                     /translation="GDVPWTPVQQWFFSQDIEERHHFNQSVMLFHSGRLSENALRPALK
                     KLAEHHDALRMVYRNDGRRWIQINQGIHESQLYSLRTSDLSQSESGWETQIKQEVADLQ
                     QSINLQEGPLLHAALFKTLTGDYLFLAIHHLVVDGVSWRILLEDLSAGYQQAASGQTIQ
                     LPPKTDSYQEYARRIQEYAQSSKLIREEAYWRSVEEQQAAELPYEIPHHVNIDSSKRDS
                     LSFSLTEADTAVLLQNVNYAYGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGREHIL
                     PELDISRTVGWFTSMYPALIS"
     CDS_motif       2379..2405
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20740_0007"
                     /evalue="3.40E-03"
                     /label="NRPS-E1"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="800"
                     /protein_start="791"
                     /score="10.6"
                     /tool="antismash"
                     /translation="WTPVQQWFF"
     CDS_motif       2460..2543
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20740_0008"
                     /evalue="5.70E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="846"
                     /protein_start="818"
                     /score="12.3"
                     /tool="antismash"
                     /translation="SGRLSENALRPALKKLAEHHDALRMVYR"
     CDS_motif       2748..2813
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20740_0009"
                     /evalue="1.30E-12"
                     /label="NRPS-E2"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="936"
                     /protein_start="914"
                     /score="39.7"
                     /tool="antismash"
                     /translation="LFLAIHHLVVDGVSWRILLEDL"
     CDS_motif       3219..3266
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20740_0010"
                     /evalue="6.00E-09"
                     /label="NRPS-E5"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="1087"
                     /protein_start="1071"
                     /score="27.8"
                     /tool="antismash"
                     /translation="DISRTVGWFTSMYPAL"
     aSDomain        3291..3752
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NHM07_RS20740_TIGR01720.1"
                     /evalue="8.20E-53"
                     /label="NHM07_RS20740_TIGR01720.1"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="1249"
                     /protein_start="1095"
                     /score="170.3"
                     /tool="antismash"
                     /translation="ELGTAVKTVKDTLGRIPNKGVGYGMLKYLTHPENKSITFSKTPEI
                     SFNYLGQFNDIERQDTFRPSSLGSGKDITHTWKREQIIEMSAMAADKKLHFNLSYPPAC
                     FHKNTMEQLINRIEHFLLDIMKHCAGQQKAEKTLSDFSSQSLTAEDLDSI"
     CDS_motif       3315..3377
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20740_0011"
                     /evalue="1.20E-09"
                     /label="NRPS-E6"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="1124"
                     /protein_start="1103"
                     /score="30.3"
                     /tool="antismash"
                     /translation="VKDTLGRIPNKGVGYGMLKYL"
     CDS_motif       3417..3446
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20740_0012"
                     /evalue="4.00E-03"
                     /label="NRPS-E7"
                     /locus_tag="NHM07_RS20740"
                     /protein_end="1147"
                     /protein_start="1137"
                     /score="9.7"
                     /tool="antismash"
                     /translation="PEISFNYLGQ"
     aSDomain        3799..3888
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NHM07_RS20745_NRPS-COM_Nterm.1"
                     /evalue="2.00E-18"
                     /label="NHM07_RS20745_NRPS-COM_Nterm.1"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="30"
                     /protein_start="0"
                     /score="57.3"
                     /tool="antismash"
                     /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDS"
     gene            3799..>10173
                     /gene="ppsD"
                     /locus_tag="NHM07_RS20745"
                     /old_locus_tag="NHM07_20745"
                     /pseudo=""
     CDS             3799..>10173
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 2e-18.
                     Score: 57.3. Matches aSDomain:
                     nrpspksdomains_NHM07_RS20745_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-305). E-value:
                     9e-119. Score: 387.9. Matches aSDomain:
                     nrpspksdomains_NHM07_RS20745_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (469-866). E-value: 4e-104.
                     Score: 340.4. Matches aSDomain:
                     nrpspksdomains_NHM07_RS20745_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (972-1041). E-value: 4.9e-24. Score:
                     76.3. Matches aSDomain: nrpspksdomains_NHM07_RS20745_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1055-1334). E-value:
                     5.4e-103. Score: 336.0. Matches aSDomain:
                     nrpspksdomains_NHM07_RS20745_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1500-1901). E-value:
                     1.2e-113. Score: 371.7. Matches aSDomain:
                     nrpspksdomains_NHM07_RS20745_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2003-2072). E-value: 1.8e-25.
                     Score: 80.9. Matches aSDomain:
                     nrpspksdomains_NHM07_RS20745_PCP.2"
                     /codon_start=1
                     /gene="ppsD"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1209: polyketide synthase associated protein papA3"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389713.2"
                     /locus_tag="NHM07_RS20745"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="NHM07_20745"
                     /product="plipastatin non-ribosomal peptide synthetase
                     PpsD"
                     /pseudo=""
                     /sec_met_domain="Condensation (E-value: 1.7e-89, bitscore:
                     286.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.5e-123, bitscore:
                     398.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.3e-17, bitscore:
                     50.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKV
                     NPQFFQNSINALVERHDIFRTIFISQNVSSPQQVVLRERNIIVLEEDITHLNEAEQSQF
                     IEQWKEKDRDRGFHLQKDVLMRIALIQTGESQYSCIWTFHHIMMDGWCLSIVLKEFLHI
                     YASYVNASPITLKPVQPYGKYIKWLMEQDKEQAVSYWDHYLSGHEQQTVLPKQKKKTKG
                     RSRQEHVTFSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISG
                     RPAEIEGIEHMVGLFINTMPVRVQGAKTLFLQLIKDMQKDRLAAEAYSYHPLYEIQSRS
                     AVKQGLIDHILVFENYPVQQEIQMLNKQEHATDLFQIHNFTVADETNYSFYLMVAPGEE
                     IHIKMNYDAEQHDRSFVLSVKEHLLNAVSQILNNPNLPPEEIDITTDTEKRQLIGEITD
                     RTPVYETIHAMFEKQAEKTPDAHAVIDQACSLTYRELNKAANRLARHLRMKGVVRQEPV
                     AIMMDRSAAFISGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSHVVSQAHLSSSLE
                     DNYIITHPEEIESKVDGSNIKSVNDADDLLYMIYTSGSTGKPKGVQFEHRNMANLLKFE
                     YTHSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEDIKRDVPQLFTFINKHQ
                     TNIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQNVLRERGIHLHNHY
                     GPSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISGASV
                     ARGYVNHDKLTSDKFSSDPFRPGVIMYRTGDLARRLEDGNIEYIGRADNQVKIRGYRIE
                     PQEIEVTLMNHPDISEAAILIWQDQNGEHELCAYYCSVQKLNAIDLRSYMASELPEYMI
                     PAKWVWVDSIPLTPNGKVDRAALPEPDASISGNPYTAPRNLLEAKLSQLFEDVLKNGHV
                     GIQDNFFDNGGHSLKATVLMSRIAKEFHVQVSLKDIFAHPTVEGLALIIREAEQNPYAA
                     IEPAEKRDTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVCKELISRH
                     EPLRTSFVSGADDEPVQRIHTEVPFTLSKETTIEGFVRPFDLSQAPLFRAGIIEVSNEK
                     HVLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQKFKKGDSYQKQ
                     ETYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQLDKEITARIKRLAHKNRSTLYM
                     TLLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRPAGNKTFEEF
                     LKEVRQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVLQNMEQQKLKMNDVQL
                     QWNDLVHPISKFDISLYVTEHDSELFCQFEYSTALFEKETIQRWASLFTTLVEHTAASP
                     ETELDNIPILTKEEERDFIESCHLFEETGYSMNQTLHYALEQQAAKTPDQTAVVFEDGA
                     MTYKELNEQANRIAWELIGRGVKSETTVAIMGRRSPEMLIGIFGILKAGGAYLPIDPDY
                     PEERISFLLEDSGTNILLLQSDGLHVPAFAGEIVYLNQTNSGLKHRLSNPNVDVLPQSL
                     AYVIYTSGSTGRPKGVEVEHRSAVNFLNSLQSRYQLNQSDVIMHKTSYSFDASIWELFW
                     WSYAGASVYLLPQGGEKEPEVIAQAIEEQKITAMHFVPSMLHVFLEHIKYRSVPIKTNR
                     LKRVFSGGEQLGTHLVSRFYELLPNVSITNSYGPTEATVEAAFFDCPPQEKLERIPIGK
                     PVHHVRLYILNQNQRMLPAGCIGELYIAGAGVARGYLNRPALTEEHFLEDPFYPGERMY
                     KTGDVARWLPDGNVEFLGRTDDQVKIRGYRVEPGEIEAALRSIEGVREAAVTVRTDSGE
                     PELCAYVEGLQRNEVRAQLERLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAAD
                     AETYTAPRNVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQV
                     PLKDVFAHPTVEGLATVIREGTDSPYEAIKPVEKQETYPVSSAQKRIYVLQQLEDGGTG
                     YNMPAVLELEGKLNP"
     aSDomain        3820..4713
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NHM07_RS20745_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="9.00E-119"
                     /label="NHM07_RS20745_Condensation_DCL.1"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="305"
                     /protein_start="7"
                     /score="387.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIMMDG"
                     /tool="antismash"
                     /translation="QDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKVNPQFFQN
                     SINALVERHDIFRTIFISQNVSSPQQVVLRERNIIVLEEDITHLNEAEQSQFIEQWKEK
                     DRDRGFHLQKDVLMRIALIQTGESQYSCIWTFHHIMMDGWCLSIVLKEFLHIYASYVNA
                     SPITLKPVQPYGKYIKWLMEQDKEQAVSYWDHYLSGHEQQTVLPKQKKKTKGRSRQEHV
                     TFSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGRPAEIEG
                     IEHMVGLFINTMPVRVQ"
     aSModule        3820..6921
                     /complete
                     /domains="nrpspksdomains_NHM07_RS20745_Condensation_DCL.1"
                     /domains="nrpspksdomains_NHM07_RS20745_AMP-binding.1"
                     /domains="nrpspksdomains_NHM07_RS20745_PCP.1"
                     /locus_tags="NHM07_RS20745"
                     /monomer_pairings="Pro -> Pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3829..3870
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0001"
                     /evalue="1.00E-04"
                     /label="C1_DCL_004-017"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.3"
                     /tool="antismash"
                     /translation="YPLSYMQEGMLFHS"
     CDS_motif       3892..4005
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0002"
                     /evalue="1.40E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="69"
                     /protein_start="31"
                     /score="49.5"
                     /tool="antismash"
                     /translation="AYVEQASFTIEGKVNPQFFQNSINALVERHDIFRTIFI"
     CDS_motif       4225..4290
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0003"
                     /evalue="5.60E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="164"
                     /protein_start="142"
                     /score="34.8"
                     /tool="antismash"
                     /translation="FHHIMMDGWCLSIVLKEFLHIY"
     CDS_motif       4336..4374
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0004"
                     /evalue="1.40E-02"
                     /label="C4_DCL_171-183"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="192"
                     /protein_start="179"
                     /score="8.5"
                     /tool="antismash"
                     /translation="PYGKYIKWLMEQD"
     CDS_motif       4612..4707
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0005"
                     /evalue="1.10E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="303"
                     /protein_start="271"
                     /score="62.8"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPAEIEGIEHMVGLFINTMPVR"
     CDS_motif       4753..4869
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0006"
                     /evalue="2.10E-20"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="357"
                     /protein_start="318"
                     /score="65.2"
                     /tool="antismash"
                     /translation="QKDRLAAEAYSYHPLYEIQSRSAVKQGLIDHILVFENYP"
     aSDomain        5206..6396
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NHM07_RS20745_AMP-binding.1"
                     /evalue="4.00E-104"
                     /label="NHM07_RS20745_AMP-binding.1"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="866"
                     /protein_start="469"
                     /score="340.4"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="FEKQAEKTPDAHAVIDQACSLTYRELNKAANRLARHLRMKGVVRQ
                     EPVAIMMDRSAAFISGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSHVVSQAHLSS
                     SLEDNYIITHPEEIESKVDGSNIKSVNDADDLLYMIYTSGSTGKPKGVQFEHRNMANLL
                     KFEYTHSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEDIKRDVPQLFTFIN
                     KHQTNIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQNVLRERGIHLH
                     NHYGPSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISG
                     ASVARGYVNHDKLTSDKFSSDPFRPGVIMYRTGDLARRLEDGNIEYIGRADNQVKIR"
     CDS_motif       5392..5433
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0007"
                     /evalue="5.90E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="545"
                     /protein_start="531"
                     /score="13.3"
                     /tool="antismash"
                     /translation="LGILKAGGAIVPVD"
     CDS_motif       5617..5673
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0008"
                     /evalue="7.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="625"
                     /protein_start="606"
                     /score="27.8"
                     /tool="antismash"
                     /translation="YMIYTSGSTGKPKGVQFEH"
     CDS_motif       6055..6081
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0009"
                     /evalue="4.80E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="761"
                     /protein_start="752"
                     /score="4.0"
                     /tool="antismash"
                     /translation="YGPSETHVV"
     CDS_motif       6190..6279
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0010"
                     /evalue="7.20E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="827"
                     /protein_start="797"
                     /score="40.7"
                     /tool="antismash"
                     /translation="PCGVPGELYISGASVARGYVNHDKLTSDKF"
     CDS_motif       6361..6426
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0011"
                     /evalue="7.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="876"
                     /protein_start="854"
                     /score="37.2"
                     /tool="antismash"
                     /translation="YIGRADNQVKIRGYRIEPQEIE"
     CDS_motif       6634..6660
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0012"
                     /evalue="4.80E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="954"
                     /protein_start="945"
                     /score="3.9"
                     /tool="antismash"
                     /translation="GKVDRAALP"
     aSDomain        6715..6921
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NHM07_RS20745_PCP.1"
                     /evalue="4.90E-24"
                     /label="NHM07_RS20745_PCP.1"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="1041"
                     /protein_start="972"
                     /score="76.3"
                     /tool="antismash"
                     /translation="EAKLSQLFEDVLKNGHVGIQDNFFDNGGHSLKATVLMSRIAKEFH
                     VQVSLKDIFAHPTVEGLALIIREA"
     aSDomain        6964..7800
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NHM07_RS20745_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.40E-103"
                     /label="NHM07_RS20745_Condensation_LCL.1"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="1334"
                     /protein_start="1055"
                     /score="336.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="DTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVC
                     KELISRHEPLRTSFVSGADDEPVQRIHTEVPFTLSKETTIEGFVRPFDLSQAPLFRAGI
                     IEVSNEKHVLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQKFKK
                     GDSYQKQETYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQLDKEITARIKRLAHK
                     NRSTLYMTLLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRP"
     aSModule        6964..10014
                     /complete
                     /domains="nrpspksdomains_NHM07_RS20745_Condensation_LCL.1"
                     /domains="nrpspksdomains_NHM07_RS20745_AMP-binding.2"
                     /domains="nrpspksdomains_NHM07_RS20745_PCP.2"
                     /locus_tags="NHM07_RS20745"
                     /monomer_pairings="Glu -> Glu"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7030..7143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0013"
                     /evalue="7.50E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="1115"
                     /protein_start="1077"
                     /score="47.3"
                     /tool="antismash"
                     /translation="AYNMPAVLELEGALDVAKLSAVCKELISRHEPLRTSFV"
     CDS_motif       7315..7380
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0014"
                     /evalue="1.90E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="1194"
                     /protein_start="1172"
                     /score="30.0"
                     /tool="antismash"
                     /translation="MHHIISDGVSVQLLIREFTDLY"
     CDS_motif       7411..7443
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0015"
                     /evalue="3.60E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="1215"
                     /protein_start="1204"
                     /score="13.2"
                     /tool="antismash"
                     /translation="QYKDYAVWQQK"
     CDS_motif       7702..7791
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0016"
                     /evalue="2.90E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="1331"
                     /protein_start="1301"
                     /score="51.8"
                     /tool="antismash"
                     /translation="DIVIGSPIAGRPHADLEAVLGMFVNTLALR"
     CDS_motif       7840..7959
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0017"
                     /evalue="7.00E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="1387"
                     /protein_start="1347"
                     /score="66.7"
                     /tool="antismash"
                     /translation="RQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVL"
     aSDomain        8299..9501
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NHM07_RS20745_AMP-binding.2"
                     /evalue="1.20E-113"
                     /label="NHM07_RS20745_AMP-binding.2"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="1901"
                     /protein_start="1500"
                     /score="371.7"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="LEQQAAKTPDQTAVVFEDGAMTYKELNEQANRIAWELIGRGVKSE
                     TTVAIMGRRSPEMLIGIFGILKAGGAYLPIDPDYPEERISFLLEDSGTNILLLQSDGLH
                     VPAFAGEIVYLNQTNSGLKHRLSNPNVDVLPQSLAYVIYTSGSTGRPKGVEVEHRSAVN
                     FLNSLQSRYQLNQSDVIMHKTSYSFDASIWELFWWSYAGASVYLLPQGGEKEPEVIAQA
                     IEEQKITAMHFVPSMLHVFLEHIKYRSVPIKTNRLKRVFSGGEQLGTHLVSRFYELLPN
                     VSITNSYGPTEATVEAAFFDCPPQEKLERIPIGKPVHHVRLYILNQNQRMLPAGCIGEL
                     YIAGAGVARGYLNRPALTEEHFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRTDDQVK
                     IR"
     CDS_motif       8485..8526
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0018"
                     /evalue="6.50E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="1576"
                     /protein_start="1562"
                     /score="16.2"
                     /tool="antismash"
                     /translation="FGILKAGGAYLPID"
     CDS_motif       8713..8772
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0019"
                     /evalue="3.10E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="1658"
                     /protein_start="1638"
                     /score="31.9"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVEVEH"
     CDS_motif       9157..9186
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0020"
                     /evalue="4.60E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="1796"
                     /protein_start="1786"
                     /score="6.9"
                     /tool="antismash"
                     /translation="SYGPTEATVE"
     CDS_motif       9295..9384
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0021"
                     /evalue="7.10E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="1862"
                     /protein_start="1832"
                     /score="53.5"
                     /tool="antismash"
                     /translation="PAGCIGELYIAGAGVARGYLNRPALTEEHF"
     CDS_motif       9466..9531
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0022"
                     /evalue="1.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="1911"
                     /protein_start="1889"
                     /score="39.0"
                     /tool="antismash"
                     /translation="FLGRTDDQVKIRGYRVEPGEIE"
     CDS_motif       9727..9753
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NHM07_RS20745_0023"
                     /evalue="5.20E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="1985"
                     /protein_start="1976"
                     /score="3.8"
                     /tool="antismash"
                     /translation="GKLDRNALP"
     aSDomain        9808..10014
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NHM07_RS20745_PCP.2"
                     /evalue="1.80E-25"
                     /label="NHM07_RS20745_PCP.2"
                     /locus_tag="NHM07_RS20745"
                     /protein_end="2072"
                     /protein_start="2003"
                     /score="80.9"
                     /tool="antismash"
                     /translation="EMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFD
                     VQVPLKDVFAHPTVEGLATVIREG"
ORIGIN
        1 acaccgcgtt cttgtcacgc ttaagcggac aggaagatat catcgtcggc tcgccaattg
       61 ccggccggcc gcacaaggat cttgagccga tactcggcat gtttgtgaac acgctggcgc
      121 ttcggacgcg cccggagggc gggaagccat tcgtacagta tttgcaggaa gtgcgtgaga
      181 cagcattgga agcctttgaa caccaagatt acccgttcga agagcttgtt gataagcttg
      241 aattgacacg ggatatgagc agaaatccgc tgtttgacgt aatgtttgtt cttcaaaaca
      301 tggatcagga atcgttggaa ctggatgaac tttgtctcaa acctgcagca aacaatgggc
      361 atcaaacgtc caaatttgat ttaaccctat atgcccagga acagccccac ggtttgctga
      421 cgttccaaat ggagtttagt actgacttat ataagaaaaa aacgatagaa aagtggcttc
      481 aatacttcat caatatgtta ctctccatca tcaaagacaa caaagccgct ctcggaacaa
      541 taaatatcct gaatgaggat gagacccatt accttatcca cgagctcaat cgtacaaaaa
      601 tagattatcc aagaaatgaa accatcagca gactctttga aatgcaggct gaacaaacgc
      661 ctaatgctgt agcaattgtc agcgacaccc aagtattcac ttacgaggac ctgaacagct
      721 gggcaaatca aattgcctca gttctacaga ttaagggtgt agggcctgat agtgttgtag
      781 ccttgttgac aggcagaaca ccagaactca ttgcaggaat gctgggcatt ctgaaagccg
      841 ggggagccta tctgcctatt gcttctgatc tgcctgttga acgaatagct tatatgctgt
      901 cagacagcgg ggcggcatta ctccttcaat ctgaaaaaac agaaaaacag ctattagaca
      961 ttgaatgtga acaaatcata atcgaagata ttcaaaagca aggagaaacg aagaacattg
     1021 attcttcagc agggccacat tcacttgcat atatcattta tacctctggt tcaaccggta
     1081 aaccaaaggg tgtcatgatt gagcagcgaa gtgtaattcg tcttgttaaa aatagcaatt
     1141 atattacatt tacacctgaa gaccgccttc ttatgacatc atcaatcggt ttcgacgttg
     1201 ggtcatttga aattttcgga ccgctgctaa atggtgccgc tttgcatctg tctgatcaac
     1261 aaacatttct cgattcccat cagcttaaga ggtacataga acatcaagga atcacaacga
     1321 tttggctgac atcttctcta ttcaatcatt tgacagagca aaatgaacaa acattttcac
     1381 agctgaaaca tttgattatt ggcggagaag ctttgtcgcc gagccacgtc aatcgaatca
     1441 gaaatgtctg ccctgaagta tctatatgga atggatatgg ccctaccgaa aatacaactt
     1501 tttcgacatg ccttcacatt caaaaaacat atgaactttc cattccgatc gggcggccgg
     1561 ttggtaattc caccgcttat atcttaaatc aatggagagt gctgcagccg gtcggagctg
     1621 tcggtgaact ttgtgtcggc ggagatggcg tcgccagagg atatttgggc cgtcctgatc
     1681 taacgaaaga gaaatttgtc ccacatccat ttgcacctgg cgatcgactg tatcgcacag
     1741 gtgatctggc gcgctggctt cctgatggca caattgaata cgttgggcgt attgatgatc
     1801 aagtaaaagt cagaggctat cgggtggagc tgggtgaaat cgaatcagca cttcgtcaaa
     1861 tagacggggt caaagaagcc gcagtgttag cacgtacagc ccagaccggg agcaaagagc
     1921 tgtttggcta tatcagcgta aaagcaggca cgaatgctga acaagtacgt tcacttctcg
     1981 cgcgttcgct gccaaactat atgatcccgg cgtacattat tgaaatggag actctcccgc
     2041 tcacatcaaa cggcaaattg aaccgaaaag cacttcctga accaaatttc acatctaaac
     2101 aaacgtacgc tccacctcga aatgaccttg aagaccaact tgtgttgatc tggcaggaag
     2161 ttctcggcat ccagaggatc ggaatagagg attcgttttt tgaattgggt ggagattcaa
     2221 tcaaagccct tcaagtttct gcacgccttg ggcgctatgg actaagcttg caggtaagtg
     2281 atttattccg tcatccaaag ataaaggact tatcaccatt tatccgtaag tcagagagaa
     2341 tcatagagca aggacccgtt cagggagacg ttccttggac gcctgttcag caatggtttt
     2401 tttcacagga tattgaagaa agacaccatt tcaatcagtc tgtcatgcta ttccattctg
     2461 gacgtttgtc tgaaaacgcc cttagaccag ccttgaaaaa actggcggag catcatgatg
     2521 cgcttcggat ggtttatcgc aacgatggca ggcgatggat tcaaatcaac caaggcattc
     2581 atgagtcaca gctatacagc ttaagaacct ctgatctttc acagtcagaa agcggctggg
     2641 agacgcaaat caaacaagaa gttgcagatc ttcagcaaag catcaatttg caggaaggac
     2701 cgttgttgca cgccgctttg tttaaaacac tgaccggaga ttacttgttc cttgcgatcc
     2761 atcaccttgt cgttgatggt gtctcatggc ggattttgct ggaggatttg tcagccggat
     2821 atcaacaagc tgcttcaggc cagacgatcc agcttccgcc taaaacggat tcctaccagg
     2881 aatacgcaag acgcatacag gaatatgccc aaagcagtaa gctgattcgc gaagaggcgt
     2941 attggcgaag tgtagaagaa cagcaagccg cagaactgcc atatgaaata ccgcatcatg
     3001 tgaacatcga ctccagcaaa agggactcat taagcttttc actgactgaa gcagacaccg
     3061 ccgtcttgct gcaaaacgtc aattacgcct atggcacaga tacacaagat attctgttaa
     3121 ccgcagcatc cttggcgatt tgtgaatgga caggcggaag caagctccgt atcgctatgg
     3181 aaggacacgg gagagaacac attctgccag agttagatat cagcaggacg gtcggctggt
     3241 ttacatccat gtacccggcc ctcataagct ttgaaaatca tagagatgag ctcggaaccg
     3301 cagtaaaaac cgttaaagat acactgggcc ggataccaaa caaaggggta ggttacggta
     3361 tgctgaaata ccttacacat cctgaaaata aaagcattac gttttcaaaa acacctgaaa
     3421 tcagctttaa ctatttgggc cagttcaacg acatcgaaag acaggacacc ttccgcccat
     3481 caagccttgg tagcggaaag gatatcactc atacatggaa gcgtgagcaa atcatcgaga
     3541 tgagcgcaat ggcagcagac aaaaagctcc atttcaatct tagttatccg ccagcctgct
     3601 ttcacaaaaa cacaatggag cagcttatta acaggattga acactttttg ctggacatta
     3661 tgaaacactg cgccggtcaa cagaaagcag aaaagacact gagcgatttc agcagtcaat
     3721 cattaacggc agaggacttg gacagcatat ccagcttggt ggaagaattg tagaaaatcg
     3781 tgacagggag acatgaacat gacaaaagcg aattcaattc aggatattta tccgctgtct
     3841 tacatgcagg aagggatgct tttccattcc ctcctgcaaa aagattcaca ggcgtatgtt
     3901 gagcaagctt cttttacaat agaaggaaaa gtcaacccgc agttttttca aaacagcatc
     3961 aacgctcttg tagaaagaca tgatattttc agaacgattt ttatcagcca aaatgtttcc
     4021 tccccccagc aggttgttct gagagaacga aatatcatcg tcctggaaga agacattact
     4081 catttaaacg aggcggagca atcacagttt atcgagcaat ggaaagaaaa ggaccgggac
     4141 cgggggtttc atttgcaaaa ggatgtgctc atgcgcatcg ctctgattca aacaggagag
     4201 agccagtact cttgcatttg gacctttcat catatcatga tggacggttg gtgcctcagc
     4261 attgtgctaa aggagtttct gcatatttac gcatcttatg taaatgcatc ccctataaca
     4321 ttgaagccgg tccagccata cggaaagtat atcaaatggc tgatggagca agacaaagag
     4381 caggcggttt cttattggga ccattatctt tccggccacg aacagcaaac cgtgctcccg
     4441 aagcagaaga aaaaaacaaa gggaagaagc aggcaggaac acgttacatt ttcattctct
     4501 aaggaagaaa gcagcagact ttcagagctt gctgcaagag aagaagtgac actcagtacg
     4561 atttttcata ctatttgggg cattctgctg caaaaatata ataataacga tgacgccgta
     4621 ttcggttctg ttatttcagg aagacccgca gaaatcgaag gcattgaaca tatggtaggt
     4681 cttttcatta atacgatgcc ggttcgggtg cagggggcaa aaacgctatt tcttcaactt
     4741 ataaaagata tgcaaaaaga ccgtcttgcc gctgaagcgt acagctacca ccctttatat
     4801 gagattcaat cccgctcagc tgttaagcaa gggctgattg atcatattct cgtatttgaa
     4861 aactatccgg tgcagcaaga gattcaaatg ctgaacaaac aggaacatgc tactgatctt
     4921 tttcagattc ataatttcac tgtcgcagat gaaaccaact acagctttta tcttatggtg
     4981 gcgccagggg aagaaattca tatcaaaatg aactatgatg cggagcagca cgatcggtct
     5041 tttgtgctct ctgtcaaaga gcatcttctg aatgctgtat cacaaatctt aaataatccg
     5101 aatcttccac ctgaagaaat cgatatcacg acagatactg aaaagcggca gctgattgga
     5161 gaaatcacag atcgaacacc agtttacgaa accatccatg ccatgtttga aaagcaagcg
     5221 gaaaagacac cagatgctca tgctgtaatt gatcaagcct gctcattaac atacagagaa
     5281 ctgaataaag cggctaacag attggcacgg catttacgaa tgaaaggcgt tgtgagacag
     5341 gaacccgttg cgattatgat ggatcgctct gcggcgttta tcagcggcgt tcttggaatc
     5401 ttaaaggcag gcggcgccat tgttcccgtt gatccgcatt acccggctga cagaatccgt
     5461 tatattctgc atgattgcgg ctgttcgcat gttgtttcac aagcgcatct ttcctcatcg
     5521 ttagaagaca attacattat cactcatcca gaagaaatcg aaagcaaagt agacggcagt
     5581 aacataaagt cagtcaacga tgctgacgat ctgctgtata tgatttatac atcaggctca
     5641 acaggtaaac caaagggtgt tcaatttgag catcgaaaca tggctaactt gctgaaattc
     5701 gaatatactc actccggcat tgactttgaa gcagatgttc tgcaatttgc gacaccttcc
     5761 ttcgacgtct gctatcaaga aatattttct gcgcttctga aaggcggcac actccacatc
     5821 gttccagaag acataaaaag agatgtgcct cagctgttta catttataaa caagcatcag
     5881 acgaatattg tgtttctccc aactgctttt atcaaaatga ttttcagcga gcgagaactt
     5941 gcgaactcgt ttcctgatgg cgtcaaacac ctgatcgcag ccggggaaca attaatgatt
     6001 tcagaccttt tccaaaatgt gttgcgtgaa cgcggcatac acctgcacaa tcattacgga
     6061 ccttcagaaa ctcatgtggt atctacgtat accattcatc ctggagaccc tattcctgag
     6121 cttccgccaa tcggtaaacc gataggctgt actgatctat atattttgaa tcatcaaaaa
     6181 cagcttcagc catgcggcgt accaggcgaa ctctatattt ccggcgcaag tgttgccaga
     6241 ggatatgtca atcacgataa actgacaagc gacaaatttt catccgaccc attcaggcct
     6301 ggtgtgatta tgtaccggac aggtgatttg gccagacggc ttgaagacgg caacatcgaa
     6361 tatatcggac gggcagacaa tcaagtgaaa atcagaggtt atcgaattga gccgcaagaa
     6421 atcgaagtca cgctaatgaa tcatccggac attagtgagg ctgccattct catctggcaa
     6481 gatcaaaacg gtgaacatga attatgcgct tactattgca gtgtacaaaa gctgaatgca
     6541 atagatttac gcagttatat ggctagtgag ctcccagaat acatgattcc ggcgaaatgg
     6601 gtatgggttg acagcatacc tcttacccca aacggaaaag tagatcgcgc agcacttccg
     6661 gagccagatg cttcaatcag cggaaaccca tatactgccc ctcgaaatct gttagaggca
     6721 aagctttcgc aactatttga agatgtgcta aagaatgggc atgtaggcat ccaagacaac
     6781 ttttttgaca atggcggcca ctcgttaaaa gcaacagtgc ttatgtcacg gatcgcaaag
     6841 gaattccatg tgcaagtttc acttaaggac atctttgctc atccgactgt tgaaggatta
     6901 gctttaatca ttcgagaggc agaacaaaat ccgtatgcag caattgaacc agcagaaaaa
     6961 agggatacat atcctgtatc ttcggcccaa aaacgaatct atgtgcttca acagcttgat
     7021 gagggtgtcg cctataacat gcctgcggtc ttagaactgg aaggtgcact ggatgtcgcc
     7081 aaactgtctg ctgtatgtaa agaactgatc agccggcatg agccgcttcg aacttccttt
     7141 gtatccggag ctgatgacga gccggttcag cgtatccaca ccgaagtgcc gtttacgtta
     7201 agtaaagaga ccactatcga gggatttgtc cgtccctttg atctcagcca ggcgccatta
     7261 tttagagcag gcattataga agtgtcaaac gagaagcatg tattgctggt ggatatgcac
     7321 catatcattt cagatggcgt atccgttcag ctcctaatcc gagaatttac cgatctttat
     7381 gcaaaccggc agcttaagcc attgcggatc caatataaag attacgccgt atggcagcag
     7441 aaatttaaaa agggagactc gtaccaaaag caggagactt actggcagca gcagtttagc
     7501 ggggatcttc ctatactgga gcttccaaca gataaacgac gtccggcaga acggcaattc
     7561 ataggcggaa aagtaacctt tcaattggac aaagagatca cggcccgcat aaagcggctc
     7621 gcccataaaa acagaagcac gctttatatg acgcttctcg ctttgtattc agcctttttg
     7681 tctcggttaa gcggtcagga tgatatcgtg attggttcac ctatcgccgg acggccccat
     7741 gccgaccttg aagctgttct tgggatgttc gtcaatacac tggctctccg cacacgcccg
     7801 gcgggtaata agacgtttga ggaatttctg aaagaagtca gacagacggc actagaagcg
     7861 tatgagcatc aggattaccc gtttgaagag cttgtggaca aactcggtgt gcagcgggaa
     7921 atgagccgga atcctttgtt tgacacaacg ctagtccttc agaatatgga acagcaaaag
     7981 ctaaaaatga atgatgtaca gcttcagtgg aacgacttgg tgcacccaat atcaaaattt
     8041 gatatttccc tatacgttac agaacatgat tccgagcttt tctgtcagtt tgaatacagt
     8101 acagctttgt ttgagaaaga aaccatccaa aggtgggcca gccttttcac cacgcttgtg
     8161 gaacatacag ctgccagtcc tgaaacagaa ttggacaata ttccaatctt aacaaaagaa
     8221 gaagagcgag atttcattga atcatgccat ctgtttgagg agacgggcta ttcaatgaat
     8281 caaacgctcc actatgcact cgaacagcag gcagcaaaaa cgcctgatca gacggctgtt
     8341 gtttttgaag atggagcgat gacctacaaa gaattgaatg aacaggctaa ccgtatcgcc
     8401 tgggagctga tcggacgagg agtaaaatct gaaacaacag ttgccattat gggaaggcgt
     8461 tctcctgaaa tgctgattgg catttttggc attcttaaag ctggcggcgc ttatctgccc
     8521 attgacccgg attatccgga agaacgaatc agctttctgc tggaggacag cggtacaaac
     8581 attctcctgc ttcagtctga cggcctgcat gttccggcat ttgcagggga gattgtctat
     8641 ctcaatcaga caaatagcgg gctgaaacat cgtttgtcca atccgaatgt ggacgttctc
     8701 ccgcaatctt tagcatatgt catctataca tccggctcta ccgggaggcc taagggtgtt
     8761 gaagttgaac atcgatcagc ggtgaatttt ttgaattccc ttcagtcccg ttatcaactg
     8821 aaccaatcag atgtgattat gcataaaaca tcttattcat ttgacgcttc aatatgggaa
     8881 ctgttttggt ggtcttatgc cggtgcttct gtttatctgc ttcctcaggg aggcgaaaaa
     8941 gaacctgaag tgatcgcgca ggctatagag gaacaaaaga tcacagctat gcattttgtg
     9001 ccttcaatgc ttcatgtatt tttagaacat ataaaatatc gctctgtacc gattaagaca
     9061 aacagactca agcgagtgtt ttctggagga gaacagctgg ggacccatct tgtctcccga
     9121 ttttacgagt tgcttccaaa tgtttcaata accaattcct atgggccaac ggaagcaacc
     9181 gtagaagctg cattctttga ttgtccgccg caagaaaaac ttgaacggat tccaattgga
     9241 aaacctgttc atcatgtcag attgtatatc ctgaatcaga atcagcggat gctgccagct
     9301 ggatgtatcg gcgaactgta cattgccgga gcaggtgttg ccagaggtta tttgaatcgg
     9361 ccggcattaa cggaggagca ttttctagaa gacccgtttt acccgggtga acgcatgtac
     9421 aaaacaggag atgtggcgcg ctggctccct gacgggaatg ttgaattcct cgggcgtacg
     9481 gatgatcagg tgaaaattcg cggctaccgg gttgaaccgg gagaaattga agcggcacta
     9541 agaagtatag aaggtgtaag agaggcggcc gttaccgtac ggacagacag cggcgagccg
     9601 gaattatgcg cttatgtaga agggctccaa agaaacgaag tgcgggcaca gcttgagaga
     9661 ctgttgccgg gctacatggt cccagcctat atgatagaga tggaacagtg gccggttacg
     9721 ccaagcggaa aactcgaccg aaacgccctg ccagctcctg gcggagcggc agatgcggag
     9781 acctacacag cgccgagaaa cgtgactgag atgaagcttt ctcagctgtg ggaggacgtg
     9841 ctgaaaaatg gccctgtcgg gattcacgac aacttttttg accgcggggg acattcctta
     9901 aaagcaacgg cgcttgtctc acggattgcc aaagaattcg atgtacaggt gccgctaaaa
     9961 gatgtatttg cccatccgac agtcgaaggg ctggctaccg ttatccgtga aggaacagac
    10021 agtccatatg aagcgattaa gcccgttgaa aaacaggaaa cctatccggt ttcctctgcc
    10081 caaaagcgga tttatgtcct tcagcagctg gaggacggag ggacaggcta caatatgccg
    10141 gctgtgttag agctcgaagg gaagctcaac cct
//
