LOCUS       NZ_CP099738            26019 bp    DNA     circular CON 27-AUG-2024
DEFINITION  Lentzea sp. HUAS12 chromosome.
ACCESSION   NZ_CP099738
VERSION     NZ_CP099738.1
KEYWORDS    RefSeq.
SOURCE      Lentzea sp. HUAS12
  ORGANISM  Lentzea sp. HUAS12
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 9676923)
  AUTHORS   Ping,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JUN-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024125735.1-RS_2024_08_27
            Annotation Date                   :: 08/27/2024 06:34:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,161
            CDSs (total)                      :: 9,080
            Genes (coding)                    :: 8,988
            CDSs (with protein)               :: 8,988
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 21 of 92
            Pseudo Genes (incomplete)         :: 77 of 92
            Pseudo Genes (internal stop)      :: 3 of 92
            Pseudo Genes (multiple problems)  :: 8 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:47:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8710684
            Orig. end                         :: 8736703
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP099738.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Ping Mo.
FEATURES             Location/Qualifiers
     region          1..26019
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="32"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..26019
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26019
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16019]"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16019
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(248..261)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.22"
                     /tool="antismash"
     misc_feature    complement(885..899)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.74"
                     /tool="antismash"
     gene            935..1681
                     /gene="atpB"
                     /locus_tag="ND450_RS40930"
                     /old_locus_tag="ND450_40930"
     CDS             935..1681
                     /EC_number="7.1.2.2"
                     /GO_component="GO:0000276 - mitochondrial
                     proton-transporting ATP synthase complex, coupling factor
                     F(o) [Evidence IEA]"
                     /GO_component="GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA]"
                     /GO_component="GO:0045264 - plasma membrane
                     proton-transporting ATP synthase complex, coupling factor
                     F(o) [Evidence IEA]"
                     /GO_function="GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA]"
                     /GO_process="GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /gene="atpB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009951074.1"
                     /locus_tag="ND450_RS40930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_40930"
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="WP_253323392.1"
                     /transl_table=11
                     /translation="MFTWHEPLGLPFDFSVTKPQALLVLSVVIILTFFLVTTRNLRLIP
                     TRWQFAAESVYDFGRNTIAREQIGAREFAPYVPLIVSIFCFVLVNNVYGLIPLVQFPTF
                     THSGFPFAIALLIIFPLYHFVGIRKFGLKGYLRNQFVIPDVPKPVLWGLLIPTEVILKF
                     FFDPVNLAIRVFAAMFAGHLLILVFTLGAEFLLFNAPIYLKPVSVLGFALAIALFFLEA
                     LVQVLQAYIFALLSAHFIGRALAEQH"
     gene            1681..2025
                     /locus_tag="ND450_RS40935"
                     /old_locus_tag="ND450_40935"
     CDS             1681..2025
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS40935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_40935"
                     /product="hypothetical protein"
                     /protein_id="WP_253323393.1"
                     /transl_table=11
                     /translation="MGMYVGVRGWLEFAQEQRAAVEEVLAAHRHDPYSDGWSVPVRPFN
                     WTLYVSYGGDVRESSVDWLRSQVAELARLRDSEGDAPAGFFLLTDERERATAWFVKDGA
                     VREGAAPAGF"
     gene            complement(2022..2636)
                     /locus_tag="ND450_RS40940"
                     /old_locus_tag="ND450_40940"
     CDS             complement(2022..2636)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.5"
                     /locus_tag="ND450_RS40940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_40940"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_089917360.1"
                     /transl_table=11
                     /translation="MNAAEVFDTLGLEYQRAWSHQPALHGTLAWFAATQPSGSRVLDIG
                     CGTGVPVARNLAKAGMKVTGLDVSPVMVDIAAEQVPDATFHKIDIRDFESPPGSWDVIC
                     AVFSLLQMTQAEIVQTLGRISTWLRPGGHFFLATVAIDVEQVTLPWMGQEIEVSSFSEE
                     NFEAHLNEAGLRVVRRSRPVFTPSYPGATPEESLHLVCQRP"
     gene            2741..5545
                     /locus_tag="ND450_RS40945"
                     /old_locus_tag="ND450_40945"
     CDS             2741..5545
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="ND450_RS40945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_40945"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_253323394.1"
                     /transl_table=11
                     /translation="MTADSDEVRTRVQNELRVSLLGALAASVDGEELALGPPRQRAVLA
                     VLALRANHVVSRSELIDAVWGEDPPASADNGIHTYVAGLRRLFEPERASRAPSSVLLST
                     DAGYLLRLSSRGSDAAVFRAHLDEAGRLRSEPLQAIRAFDAALGLWRGIALDGVPGPFA
                     AVERARLAELRLTAVEQRAALMLTVGREAEVAGELTTLVSAHPLRERLHGLLMSALYRG
                     GRQAEALAVYTDLRRLLIEELGIEPGPELRQLHEQVLVGRHDPQPEPVAPALVPVQLPH
                     EIRDFTGREKELAKLSEVVPQDHSPVLVAITGTGGVGKTALAVRFAHQVASRFPDGQLH
                     VDLRGFDSSAPPVQPGTALHQLLQSLGVPSERIPEDLPAKSALYRSVLAGKRVLVLLDN
                     ARLAEQVRPLLPGRSTSMVLVTSRNHLGGLVARDGAHSLTLSTLTRDEGLTLLTSAVGA
                     DRVAAEPAAAAKLVELCGHLPLAVRIAAERVVTRPHLTLADLAGDLADERDRLNVLATG
                     DDEDTAVRAAFSWSYLALKPDAARVFRLIGLHPGAEISLGAVAALAGVPVSRARTLLDV
                     LAGGHVLEEVARGRFRLHDLLRLYATELSATEESSGGRDEAVKRLLGWYFDTANAAGTV
                     IAPPDHPAFLLPPLSTQDFSSHDEAFTWCRTESSNLLAVARLAEEHDSPAAWQIPVALW
                     NYFIVSSALDEWTRTYRVAERAAARDGNQAARSWAVHGQGLAAFRGERFADALELFDRA
                     LAIRREIGDPVGAAWSLTGLGMAYGGLRQFDLAVDRFGEALRGHVEVGSWFGEGGTRLF
                     LSDILRSAGQFEAALESARRALELMDSHDAPHGKAMALVGIGWAQSKLGRPAEGRDSFR
                     QAIEFLRVLGDRKSLAEALHGLGATSAGQPEVARTHLLEALTIYEDYDHPLTPEVRARL
                     HELS"
     misc_feature    3257..3259
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5594..6274
                     /locus_tag="ND450_RS40950"
                     /old_locus_tag="ND450_40950"
     CDS             5594..6274
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020418107.1"
                     /locus_tag="ND450_RS40950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_40950"
                     /product="hypothetical protein"
                     /protein_id="WP_253323395.1"
                     /transl_table=11
                     /translation="MQKRARTLLVWLHVVTSVGWLSQALALFTLLLYGLKTGDADAFRM
                     ARVLDHHVLAFMGATSAFSGMMLSATTPWGYFKHWWVLGKFVITVVQLYVGIFVLSGRL
                     EAAANGDVSAWTPVGTALMVAGFAFQTWLSVAKPWGRTPWADPKVKLPTASTKAFVLAL
                     TIPLVDLGLGLWMGNPMPLTMLVTVVVYSIRRAARGRRRSSDASGRGTSARPARRGATA
                     PSPR"
     gene            complement(6171..6944)
                     /locus_tag="ND450_RS40955"
                     /old_locus_tag="ND450_40955"
     CDS             complement(6171..6944)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015104297.1"
                     /locus_tag="ND450_RS40955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_40955"
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="WP_371927559.1"
                     /transl_table=11
                     /translation="MSTPLFWRVLMVVDRGLIALTGKLEVSGDIPPELLGKPLLLASNH
                     IGNLDPMVLIAACRKIGVNPRFMLAGGLLDAPVMGPALKACGHLRVDRRSANVGEAMHR
                     AVEALNKGGDPIAVYPEGRISTDPGLWPERGKTGVARMALGGGIPVVPISQWGAHEAVY
                     WGNLSVSGWRDVLPYLTSWLRAVRKRPTFKVHFGKPVELSDLRAETAGDARRAHERIMT
                     AITEGLVPLRLDEPDVPKFHDPTRPTTGASPWRPA"
     gene            7063..9447
                     /locus_tag="ND450_RS40960"
                     /old_locus_tag="ND450_40960"
     CDS             7063..9447
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0015616 - DNA translocase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020674372.1"
                     /locus_tag="ND450_RS40960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_40960"
                     /product="DNA translocase FtsK"
                     /protein_id="WP_253323396.1"
                     /transl_table=11
                     /translation="MAGRTGTSRKTTSRGKAPAKPRARSTASRKPAARKSGGAISAVWG
                     ALGRGVGSVVRTVSRTKDLDPEHRRDGLGLLLIALAFITGAGVWWQAGGPVGQWVDVAV
                     RSSVGFPAVVVPVVLLGIGVTLMRTDPKPDARPRLIIGSFLMIIGVLGMFHLIGGLPMD
                     PLERRDAGGALGYLAGGFLAQGLTPWVAGPLLFLIFAYGLLVVTHTPIRQAPERIRSLL
                     HPGKPAEPSPFDEEEPVEEPKPVRLRRPSRRRQAVEPVAADEPQAELPLEEPVEPPPPS
                     PKPSKKAAAAPALVVRAVEGEYQLPPPDVLKDGDAPKTRSRANDQMIEAITGVLDQFSI
                     DAQVTGFTRGPTVTRYEVELGPGVKVEKITALTKNIAYAVATDNVRLLAPIPGKSAVGI
                     EVPNSDREMVRLGDVLRAPSTVKDTHPMVIGLGKDIEGHMVTANLTKMPHLLVAGSTGS
                     GKSSFVNSMLVSLLARATPDEVRMILIDPKMVELTPYEGIPHLITPIITQPKKAAAALA
                     WLVEEMEQRYQDMQVNRVRHVDDFNRKVKSGEITAPPGSERVYRPYPYIMAIVDELADL
                     MMTAPRDVEDAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTD
                     SRVILDQPGAEKLIGMGDALYLPMGAGKPVRIQGAFVGDEEISSIVEFTKNQAQPEYTD
                     GVTAQKAGEKKEIDADIGDDLELLVQATELIVTSQFGSTSMLQRKLRVGFAKAGRLMDL
                     LETRGVVGPSEGSKAREVLIKPDELENVVYLMRGGGPADDE"
     gene            complement(9449..9916)
                     /locus_tag="ND450_RS40965"
                     /old_locus_tag="ND450_40965"
     CDS             complement(9449..9916)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017981803.1"
                     /locus_tag="ND450_RS40965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_40965"
                     /product="phospholipase"
                     /protein_id="WP_253323397.1"
                     /transl_table=11
                     /translation="MSNTLRSAFAGATASLALVLTGTPALAVDVVAVTDDYLYSKSLSQ
                     FTALRAQQPDADQLDWSSDGCSYSPDNPFGFKFLPTCHRHDFGYRNYKRQARWNEANRL
                     RIDNNFKADMYNQCGSSWACKRTADLYYAAVREFGGSASSTATSIQQAGLK"
     gene            complement(10001..10654)
                     /locus_tag="ND450_RS40970"
                     /old_locus_tag="ND450_40970"
     CDS             complement(10001..10654)
                     /EC_number="1.7.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013077.5"
                     /locus_tag="ND450_RS40970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_40970"
                     /product="nitroreductase family protein"
                     /protein_id="WP_253323398.1"
                     /sec_met_domain="PF00881 (E-value: 2.6e-20, bitscore: 72.2,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDDFWAASRFSPLHQRRLGDRLRDFRPPSRLVDPLEPPTSPVPL
                     PRPNDRLQKLFRARRSTREFTGEPLSDKQLGTVLGALSDDSVPSAGGLNPLRCYAFVHG
                     RAVRYDIRRHALQDLGPAPDDLAEILGTPSAPPLTIVLVLADKDSFEKYGERAGRFGLI
                     EAGAAAQTICLRLAQEKLGGYLLGGVADNEMLHSLGLPRELRVATAIACGHMIT"
     gene            complement(10660..11814)
                     /locus_tag="ND450_RS40975"
                     /old_locus_tag="ND450_40975"
     CDS             complement(10660..11814)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014661.5"
                     /locus_tag="ND450_RS40975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_40975"
                     /product="YcaO-like family protein"
                     /protein_id="WP_253323399.1"
                     /sec_met_domain="YcaO (E-value: 1.3e-29, bitscore: 103.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVAEALVERAVGWRQGVVSQLHPVPHSLSDVDLEGWAAVPEPF
                     ATGGTSGGTTRVAAIAEALERHAAARARLEVVTEGECWPLEHFSLHTVEQRVAPNYRYR
                     KGYVDTPYTRAWTLPGNDPIRVPAGLVALDASYGLPATSSGLAAGASTTSALLRAVQEL
                     VERDAFTTTWLHSLAPQRFDADLPHGAQAFDLTPAYSPHPVVAVAGSLPIAGRSRPTLG
                     LACRATTAEAVRKAYEEWVQGTVFVEVWLARNGDGPVEEATDFDEHAAYYATHPAKWDD
                     LPWFQGFEADPPPDAQARGTTAELTELVHALDRAGVRLAYRELTTPELSAVGLHCVRVL
                     SPDLAPLHSDHRWPHLGGRAAELDWRYPHASPGAFPNPAPHPLG"
     gene            complement(11811..12344)
                     /locus_tag="ND450_RS40980"
                     /old_locus_tag="ND450_40980"
     CDS             complement(11811..12344)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS40980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_40980"
                     /product="hypothetical protein"
                     /protein_id="WP_253323400.1"
                     /transl_table=11
                     /translation="MNATAVRLPDQFSPGAAAANAATPTCCCCCCCCAVSSVGAAVHIP
                     AALHRETQDLPRPRSLLVLPAAIFPLLVVVLPFATMGAVFDLHWGWWLGGFAAALAWAA
                     ASGFLARSPNPVGSVVRLLGWSVLWFLEPFVVLFTLGPIASVDEGVAAVVGVLYVGGAL
                     ALGYWIFRRYRGKR"
     gene            complement(12316..13110)
                     /locus_tag="ND450_RS40985"
                     /old_locus_tag="ND450_40985"
     CDS             complement(12316..13110)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS40985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_40985"
                     /product="hypothetical protein"
                     /protein_id="WP_253323401.1"
                     /transl_table=11
                     /translation="MSLVADPAWHAQVRDEGLVVYAGADLAYLIPDLPRAVAVALAGLF
                     EPVLRGAARTVDENRLGEPVRQHVAQLRTLGALRPAGLPTGDAKKPMGVGTRVVGEAPA
                     GLVERLPHDEDPDLLLVVRTTGTLVDLVEVARETEVPHLLLDLAYHHTAAVGPFVVPGA
                     GACLACLAVRAGRRWGDPPPPPHPAATSYEFPISLALQAVQNIRDGSLALLDTVVTVHL
                     DEFTTTRESVLPAAGCEVCPTVEFGRVSLPWGNHERDGSAVT"
     misc_feature    complement(12321..12323)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13094..13945)
                     /locus_tag="ND450_RS40990"
                     /old_locus_tag="ND450_40990"
     CDS             complement(13094..13945)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015804500.1"
                     /locus_tag="ND450_RS40990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_40990"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_245786200.1"
                     /transl_table=11
                     /translation="MPESLTVDELAARIGLPSSTIRMYQTKGVLHAPRRQGRVAYYDAS
                     HVERLTLVQRLQQRGFSLPAIAELISAREKGESVAAVLGMGETEGPDDWVRIKVRDIRH
                     LVPMGEVQPRLLLRAMRLGLVRWKYGWPHARRWALEAGGRLAGLRVPSDDVMDSFTRLR
                     TATDAVAADFVRLFERQFWPELARKAGDENQLENVRALLVELTYTAETAVVGTLRESIR
                     DAAEEFASRHGLLPSDDYQPAWAEQPLPPIAENLMDPAGDLPSEQEIENFLKRGDEDEP
                     GR"
     gene            complement(14009..14509)
                     /locus_tag="ND450_RS40995"
                     /old_locus_tag="ND450_40995"
     CDS             complement(14009..14509)
                     /EC_number="2.3.1.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020498372.1"
                     /locus_tag="ND450_RS40995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_40995"
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="WP_256557388.1"
                     /transl_table=11
                     /translation="MTSGVVVRRARTSDVRAMKALIDGYAGKVLLAKPLVTLYEAVQEF
                     WVAEEDGELLGCGALHVMWEDLAEIRSVAVSPMALGKGVGHRIVAQLIATAKELQLARI
                     FCLTFETKFFNKHGFVEIEGTPVSPEVYEEIMRSVDEGVAEFLDLSYVKPNTLGNSRML
                     LEL"
     gene            14616..16019
                     /gene="rimO"
                     /locus_tag="ND450_RS41000"
                     /old_locus_tag="ND450_41000"
     CDS             14616..16019
                     /EC_number="2.8.4.4"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008172 - S-methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0018339 -
                     peptidyl-L-beta-methylthioaspartic acid biosynthetic
                     process from peptidyl-aspartic acid [Evidence IEA]"
                     /codon_start=1
                     /gene="rimO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015804498.1"
                     /locus_tag="ND450_RS41000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_41000"
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="WP_253323402.1"
                     /sec_met_domain="PF04055 (E-value: 1.8e-21, bitscore: 76.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPTTPRRVSLLTLGCARNEVDSEELAGRLGEGGWELVDEGADV
                     VVVNTCGFVEQAKKDSVDTLLAASDTGAKVVAVGCMAERYGKELADSLPEAAAVLGFDQ
                     YNDLAERLQDVLHGKPVESHVPVDRRTLLPITPVKRQEAKDAVQVPGHGWGPTNTPRKR
                     LDDAPVAPLKIASGCDRRCSFCAIPSFRGAFVSRHPDEIVSEAMWLAENGVKELFLVSE
                     NSTSYGKDLPREQGALEQLLPRLASVPGVERVRVSYLQPAETKPSLVAAIAKTDKVANY
                     FDMSFQHSSENVLRRMRRFGDTDSFLKLVWQIREHAPEAGIRSNFIVGFPGETEADLQE
                     LERFLTEARLDAVGIFGYSDEDGTEAEELDGKLDADVIAERVQRIGNLVEELTSQRAED
                     RVGTEVTVLIETEEDDENDCVGRAEHQAPEVDGECIVLEAEGLRRGDFVRCRVVDSEGV
                     DLIVEVVPT"
     gene            16016..16594
                     /gene="pgsA"
                     /locus_tag="ND450_RS41005"
                     /old_locus_tag="ND450_41005"
     CDS             16016..16594
                     /EC_number="2.7.8.5"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015804497.1"
                     /locus_tag="ND450_RS41005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_41005"
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="WP_253323403.1"
                     /transl_table=11
                     /translation="MTEARKVPLLNVANILTMARLALVPVFLFSLFEAGGFDTTWRLIA
                     FAIFAIASFTDHIDGTLARKHGLITDFGKIADPIADKALTGSALVGLSILDVLPWWITI
                     TIAVREIGITLLRFWVIRYGVIPASRGGKAKTLAQVIAIGLFVLPQNDVLGLIAWVIMA
                     VALVLTIVTGIDYVIHAFKMKARAGRAVL"
     gene            16591..17067
                     /locus_tag="ND450_RS41010"
                     /old_locus_tag="ND450_41010"
     CDS             16591..17067
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009153794.1"
                     /locus_tag="ND450_RS41010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_41010"
                     /product="CinA family protein"
                     /protein_id="WP_253323404.1"
                     /transl_table=11
                     /translation="MTGVVELLEARNETVATAESLTAGLLCATIVDTPGASAVVRGGLI
                     VYATELKHELAGVDQQLLDEHGAVHPDVAIQLAEGARTRCGADWGIGLTGVAGPDPQDG
                     VAPGTVHIGLSGPGVSTVRTITLSGDRAAVRSAAVEKALVLLSDTLLAVDSGNK"
     gene            17173..17595
                     /locus_tag="ND450_RS41015"
                     /old_locus_tag="ND450_41015"
     CDS             17173..17595
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006240058.1"
                     /locus_tag="ND450_RS41015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_41015"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_089917334.1"
                     /transl_table=11
                     /translation="MTVLLREAIGDRLRHARTNQRRTLREVSRTARVSLGYLSEVERGR
                     KEASSELLAAICEALELPLSELLHHVASDIGAVQQTPDTVPDTVPDGRSERGKLEGGRV
                     LPSTLSDDLSDLRLQPMLTHRLTSKIGETPKAVVAA"
     gene            17955..18806
                     /locus_tag="ND450_RS41020"
                     /old_locus_tag="ND450_41020"
     CDS             17955..18806
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015804494.1"
                     /locus_tag="ND450_RS41020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_41020"
                     /product="PspA/IM30 family protein"
                     /protein_id="WP_089917332.1"
                     /transl_table=11
                     /translation="MASPFVKFWKYLMASFSSKIDEHADPKVQIQQAIEEAQRQHQALS
                     QQAAAVIGNQRQLEMKLNRQLGDVEKLQASARQALVLADEARAKGDEQKATQFENAAQG
                     FATQLVTAEQGIEDLKTLHDQSLQAAAQAKQAVERNSMMLQQKLAERTKLLSQLEQAKM
                     QEQVSASLNQMSELAAPGNVPSLEEVRDKIEKRYSTALGSAELAQNSVQGRMLEVQAST
                     TQLAGSSRLEQIRASMHGGQSSTPQQVTAGNSAAAQIQAEIAQRVQSEQKTQQQQVPPA
                     QN"
     gene            18848..19669
                     /locus_tag="ND450_RS41025"
                     /old_locus_tag="ND450_41025"
     CDS             18848..19669
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015104287.1"
                     /locus_tag="ND450_RS41025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_41025"
                     /product="hypothetical protein"
                     /protein_id="WP_253323405.1"
                     /transl_table=11
                     /translation="MEPWRNRPNNEIVRKVVGELGASLQGHPLAEQARYRLQKWNDPVA
                     KLERKRKRTNAVLTFWLIVISMLGTLAVLGFTGVLGTWAAVTGSIGAAVPAVLAVRSGF
                     KLKELGVARQRLALSPPPRPRPPLPAHISSARVPMEKLHSAEDAMAQLLVQLDSPALTS
                     MPTESVQHARQTAQEAATAIRAVSAQLQAVERARDNAPPLERAPLVEGVRVLRIQLADG
                     VDRYCALVAEAGKALAASTQFQNPGEVLDDATDHMAGLASAMRDVSGYSAH"
     gene            19906..21090
                     /locus_tag="ND450_RS41030"
                     /old_locus_tag="ND450_41030"
     CDS             19906..21090
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943107.1"
                     /locus_tag="ND450_RS41030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_41030"
                     /product="uracil-xanthine permease family protein"
                     /protein_id="WP_371927560.1"
                     /transl_table=11
                     /translation="MSWPLTIGFGVQHLVAMFGATVIVPTATGLPVATTLLFSGLGTLL
                     FLVITKNRVPSYLGSSFAFVAPLVAAREQGIAAQLGGVVAAGLLVIVVGIAVKALGVRL
                     LESVMPPVVTGAVVILIGLNLSRQATANFGEQPLLAALTTVVILLAGVLGRGLVFRFSI
                     LIGFVAVWMGGLAFGAVPSERIAALREAAWVGLPKLYQPELRPSVVLLMLPVVIVLVAE
                     VVGHVKAVAALTGRNLDGSAGDAIIANGLSTALSGLGGGAGTTTYSENIGVMAVTRVYT
                     TAAFAFAGVFATLLAFSPKAIALFGTIPPGVLGGCTLVLYGLIVLIGVRIWMDRGVDLA
                     SPVNAMVGGAALVAGVGDLTVEIGDLEMGGMVWGSLLVVILHPVMRWLRAARRS"
     gene            complement(21263..22240)
                     /locus_tag="ND450_RS41035"
                     /old_locus_tag="ND450_41035"
     CDS             complement(21263..22240)
                     /EC_number="1.3.5.2"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006222 - UMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015104285.1"
                     /locus_tag="ND450_RS41035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_41035"
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="WP_253323407.1"
                     /transl_table=11
                     /translation="MVYKQVVRRALFGMHGGDAERVHETTLDVMARLSPLARFARGQNN
                     PRTVFGVRFPNPVGLAAGLDKDGRALPVWAALGFGFVEVGTVTWHAQPGNPKPRLFRLR
                     EDEAIINRMGFNNAGAQALAAKLDRTPLKAPLGISLGKSKVTPVEDAVQDYLNSLNALK
                     DHGDYYAINVSSPNTPGLRSLQDKGALTELVAELTKATTKPMLVKIAPDLTEDAIAEVI
                     QVCVDNGIKGLIATNTTLSREGLTSAHQNETGGLSGRPLTRRANDVVRFITKNSDLPVI
                     GVGGIATADDAKRMIDAGASLVQIYTGFIYEGPGLVSRINRALR"
     gene            complement(22278..23519)
                     /locus_tag="ND450_RS41040"
                     /old_locus_tag="ND450_41040"
     CDS             complement(22278..23519)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="ND450_RS41040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_41040"
                     /product="cytochrome P450"
                     /protein_id="WP_253323408.1"
                     /sec_met_domain="p450 (E-value: 1e-17, bitscore: 63.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVNLDALRPGFTDDPYAVLKSLRDAGPVHRVETLGVPMWLVTRY
                     PDVRAALDNPLLSSHGSALAEPLRGHPHFASWWFGDLSDHMMNSDEPNHTRLRRAVSSQ
                     LTPRRIAALRPRIEQVAASLADGFADAGRCDLIADFAAPLPIAVIMELLGVPAVDQENF
                     RYWADVVTGLADGDAASAREETSDYLRDLVTHKRTSGDDDLIGGLARATGETALTDDEL
                     ASLAFLLLVAGYTTAVDLVGNGALALLRDPEQLELLQRSSSLLPGAIEEFLRFDGPTSH
                     VVRFATKPLTIGGVQIPAGDVVLLSLASAEHDPNRYPRADQLNIERADRQHLAFGHGIH
                     FCLGAPLARLEGEIAFRTLLGRCAGLALDTSQPLGWRVSLGSRGLRALPVTFLAKPKMP
                     LDEQATIKVAKPTM"
     gene            complement(23552..24313)
                     /locus_tag="ND450_RS41045"
                     /old_locus_tag="ND450_41045"
     CDS             complement(23552..24313)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332656.1"
                     /locus_tag="ND450_RS41045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_41045"
                     /product="Fpg/Nei family DNA glycosylase"
                     /protein_id="WP_253323409.1"
                     /transl_table=11
                     /translation="MPEGDTVFLAGHRMNEALAGKTLRRGELRHPRLAALDLAGLDVLG
                     VRTYGKHMFTHFSDGNSLRSHFRMDGSWHLYRPGERWRRPAHQARAVFEVDDRQAIGFA
                     LHDMEFVPTAEEDRLISHLGPDLLAPDFDSAEAVRRLTAAPSRPIGLALLDQRVMAGVG
                     NLYRAEVCFLLRVLPTAPVSAADASRAVALSRKLLQANQWRPEQSTTGDLRVQHYVFER
                     TGKPCLRCRTRVRSDEIDGRFVYFCPKCQSG"
     gene            complement(24306..25151)
                     /locus_tag="ND450_RS41050"
                     /old_locus_tag="ND450_41050"
     CDS             complement(24306..25151)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1157: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015804487.1"
                     /locus_tag="ND450_RS41050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_41050"
                     /product="ParA family protein"
                     /protein_id="WP_089917323.1"
                     /transl_table=11
                     /translation="MHTVSVLSLKGGVGKTTVVLGLASAALRRGVRTLVIDLDPQCNAT
                     STLEPEESKASIYDVLQDPSEENLEQAIRPSRWGDGIDVLSGSEDAELLNHPDPGESRL
                     HRLKDALRTLRDMYDEFPYHLVLLDCPPSLGQLTRSALVAADRALLVTEPTMFAVAGVQ
                     RAFEAVQNERESNNADLQPLGVVVNRVRPRSHEHQFRIDELRDIFGPLVMPVALPDRLA
                     VQQAQGACMPIHEWGTPGAREVALAFNLLLARIQRISRSRRRAVHHDFDDDEIQEAVDA
                     "
     gene            25185..25904
                     /locus_tag="ND450_RS41055"
                     /old_locus_tag="ND450_41055"
     CDS             25185..25904
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015804486.1"
                     /locus_tag="ND450_RS41055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_41055"
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="WP_253323410.1"
                     /transl_table=11
                     /translation="MRPDAVHRVLDAELAAARERRGGQHPRVLDVGGGSGVWAVPLAAA
                     GCAVTVVEPSPNALATLNTRAREAGVTINAVQGDTDALGVPAGEADLVLAHGLLEVVDD
                     APAALASLAAAVAPGGAVSVVVANRFAAILHRAIAGRIVDARRLLDDDAGQLAGTRDPL
                     QRRFDVPGLEKLVLEAGLSVELLQGHGIVADLVPGVVLDANPGAADALAELELAAATRS
                     PLRDVAARLHVLARRTA"
ORIGIN
        1 agaacgaggt cctcttcgtc tccacggggt cgcagggcga gccgctgtcc gcgctgtcgc
       61 gcatggcccg cggcgagcac cgccagatct cgatccgcga gggcgacacg gtcatcctcg
      121 cgtcgtcgct gatccccggc aacgagaacg cggtcttcaa cgtcgtcaac ggcctcgcca
      181 agctcggcgc gaccgtcgtg caccagggca acgccaaggt gcacgtctcc ggccactcgc
      241 cggcaggcga actcctgttc ctctacaacg ccgtgcggcc gtccaacgtg atgcccgtgc
      301 acggcgagtg gaggcatttg agggccaacg cggctctcgc cgtcgccacc ggtgtcgccg
      361 aggaccacgt cgtgatcgcc gaggacggcg tcgtcgtgga cctgatcgac ggcaaggccg
      421 cggtctcggg ccgggtcgtc gtgggccacg tgtacgtcga cggcctgtcc gtgggcgacg
      481 tcggcgagtc gacgctgtcc gaccgcctgg tgctcggcga gggcggcttc atctcgatct
      541 cggtcgccat cgagcaggcg accggccgtg ccgtgacgtc gccgacgatc tccggccgcg
      601 gcttctccga cgaccccaag gcgctggagg ccgtggtgcc gctcgtggag atggagctgg
      661 cgcgcacgga ggccgagggc atcaccgaca cgcaccgggt cgcgcaggcc gtgcgccgcg
      721 tcgtgggccg ctgggtggcg gagacctacc ggcgccgtcc gatgatcgtt cccacggtca
      781 ttccggtctg acacttccgg gggtttccgt gaccccgctg tgatctgcgt ccccctcgtc
      841 cgataaggtc tgatcccaga ccatggacga gggggttcgc ccaatggccg atgttttcca
      901 accgccgggt aaagacgaca ttcttctccc gccgatgttc acctggcacg agccgctagg
      961 cctgccgttc gacttctccg tcaccaaacc gcaggccctg ctggtgctgt cggtggtgat
     1021 catcctgacg ttcttcctgg tcaccaccag gaacctccgg ctgatcccga cacgctggca
     1081 gttcgccgcc gagtcggtct acgacttcgg ccgcaacacc atcgcgcgtg agcagatcgg
     1141 cgccagggaa ttcgcgcctt acgtgccgtt gatcgtcagc atcttctgct tcgtgctcgt
     1201 caacaacgtc tacgggctga tcccgctcgt gcagttcccg acgttcacgc acagcgggtt
     1261 cccgttcgcg atcgcgttgc tgatcatctt tccgctctac cacttcgtgg gcatccgcaa
     1321 gttcgggctg aagggctacc tgcgcaacca gttcgtcatc ccggacgtgc cgaagcccgt
     1381 gctgtggggg ctgctcatcc cgaccgaggt catcctcaag ttcttcttcg acccggtgaa
     1441 cctcgcgatc cgggtgttcg cggcgatgtt cgcggggcac ctgctgatcc tggtgttcac
     1501 gctcggtgcc gagttcctgc tgttcaacgc gccgatctac ctcaagccgg tgtcggtgct
     1561 ggggttcgcg ctggcgatcg cgctgttctt cctggaggca ctggtgcagg tgctgcaggc
     1621 gtacatcttc gcgttgctgt cggcgcactt catcgggcgc gcgctggcgg agcagcactg
     1681 atggggatgt acgtgggcgt acggggctgg ctcgagttcg cgcaggagca gcgcgcggcg
     1741 gtcgaggagg tgctggccgc gcaccggcac gacccgtact ccgacgggtg gtcggtgccg
     1801 gtgcgaccgt tcaactggac gctctacgtg tcctacggcg gcgatgtccg cgagtcgtcg
     1861 gtggactggt tgcgctcgca ggtcgccgaa ctggcccggc tccgggactc cgagggggac
     1921 gcgccggccg gtttcttcct gctgaccgac gaacgtgagc gggcgacggc gtggttcgtg
     1981 aaggacggcg ctgtgcggga aggagcggca ccggccggct tctaggggcg ctggcacacc
     2041 aggtgcagcg actcctcggg cgtggcgccg gggtacgacg gcgtgaacac cggccggctc
     2101 cggcgcacga cccgcagccc ggcctcgttc aggtgcgcct cgaagttctc ctcggagaac
     2161 gacgacacct cgatctcctg gcccatccag ggcagggtga cctgttcgac gtcgatggcg
     2221 acggtggcga ggaagaagtg gccgccgggc cgcagccacg tcgagatgcg gccgagggtc
     2281 tgcacgatct cggcctgggt catctgcagc agcgagaaga cggcgcagat gacgtcccac
     2341 gaaccgggag gtgactcgaa gtcgcggatg tcgatcttgt ggaacgtcgc gtcggggacc
     2401 tgctccgccg cgatgtcgac catcaccggg gacacgtcga ggccggtgac cttcatgccg
     2461 gccttggcga ggttgcgggc cacgggaacg cctgtgccgc aaccgatgtc gagcacgcgc
     2521 gagcctgacg gctgggtcgc ggcgaaccag gcgagggtgc cgtgcagtgc gggctggtgc
     2581 gaccaggcgc gctggtattc cagtccgagc gtgtcgaaga cctccgccgc gttcatccgc
     2641 cgcccctcat ttcggcccaa tccacctgag tgaagtgttg agtacgtctc tgcacgcctt
     2701 ctggatggcc tctggacgaa aactgacggt aggttgctag gtgactgcgg acagcgacga
     2761 agtgagaacc agggtgcaga acgagttgcg cgtcagcttg ctgggcgcgc tcgcggcctc
     2821 ggtggacggc gaggagctcg cgctcggtcc gccgcggcag agggctgttc tcgctgtgct
     2881 cgccttgcgt gccaatcacg tcgtgtcgcg cagtgaactg atcgacgccg tgtggggtga
     2941 agatccccct gccagcgccg acaacggcat ccacacgtac gtcgccgggc tgcgcaggct
     3001 gttcgagcct gagagggcgt cgcgggcgcc gagttccgtg ttgctctcca cggacgctgg
     3061 atatttgctg aggctcagtt cgcgtggttc ggacgctgcc gtgttccgcg cgcatctgga
     3121 cgaagccgga cgcctgcgga gcgagccact gcaagccatc cgggcgttcg acgcggccct
     3181 ggggctgtgg cggggaatcg cgctcgacgg cgtgccgggg ccgttcgcgg cggtggagcg
     3241 cgcgcgtctg gccgagttac ggctcacggc cgtggagcag cgtgcggcgt tgatgctcac
     3301 ggtcgggcgt gaggccgagg tggcggggga gctcaccacg ctggtgagcg cgcatccgtt
     3361 gcgggagagg ctgcacggac tgctcatgtc cgcgctctac cgcggcggca ggcaggcgga
     3421 ggcgctcgcc gtctacacgg acctgcgccg gttgctcatc gaggagctcg gcatcgagcc
     3481 cggcccggaa ctgcgccagt tgcacgagca ggtgctcgtc ggccggcacg acccgcagcc
     3541 cgaaccggtg gcgcccgcgc tggtgcccgt ccagctgccg cacgagatcc gcgacttcac
     3601 cggccgggag aaggagctcg cgaagctctc cgaggtcgtg ccgcaggacc actcgccggt
     3661 gctcgtcgcg atcaccggca ccggtggcgt cggcaagacg gcgctggccg tccgcttcgc
     3721 ccaccaggtg gcatctcgtt tccccgacgg tcagctgcac gtcgacctgc gcgggttcga
     3781 ctcgtcggcg ccgcccgtgc agcccggcac cgcgttgcac cagctgttgc agagcctcgg
     3841 cgtgccgtcc gaacgcatcc cggaggacct gccggcgaag tccgcgctgt accgcagcgt
     3901 cctcgcgggc aaacgggtcc tggtgctgct ggacaacgcg cggctggccg agcaggtccg
     3961 cccgctgctg cccggccggt cgacgtcgat ggtcctcgtg acgtcccgca accacctcgg
     4021 cggtctcgtc gcccgcgacg gcgcgcactc gctgacgctg tcgaccctca cgcgcgacga
     4081 gggcctgaca ctgctgacgt ccgcggtggg ggccgaccgg gtggccgccg aacccgctgc
     4141 cgccgcgaag ctcgtcgagc tgtgcgggca cctgccgctg gcggtgcgga tcgcggccga
     4201 acgggtcgtc acccggccgc acctcaccct cgccgacctc gcgggtgacc tggcggacga
     4261 acgcgaccgg ttgaacgtgc tggccacggg cgacgacgag gacacggccg tacgtgccgc
     4321 cttctcgtgg tcgtacctcg cgctcaagcc cgacgccgcg cgcgtgttcc ggctgatcgg
     4381 cctgcacccc ggtgccgaga tcagcctggg cgccgtggcg gcgctcgccg gtgtgccggt
     4441 gtcgcgggcg cggacgttgc tcgacgtgct ggcgggcggg cacgtgctgg aggaggtggc
     4501 gcgcggccgg ttccggctgc acgacctgct ccgcctgtac gccaccgagc tcagcgccac
     4561 cgaggagtcg tcgggtggcc gcgacgaggc cgtgaagcgc ctgctgggct ggtacttcga
     4621 caccgcgaac gcggccggca ccgtgatcgc gccgccggac cacccggcgt tcctgctgcc
     4681 gccactgtcc actcaggact tctcctcgca cgacgaggcg ttcacgtggt gccgcacgga
     4741 gtcgtcgaac ctgctggcgg tggcgcggct cgccgaggag cacgactcgc ccgcggcgtg
     4801 gcagatcccg gtggcgctgt ggaactactt catcgtgtcg agcgcgctgg acgagtggac
     4861 ccgcacgtac cgcgtcgccg aacgggccgc ggcgcgggac ggcaaccagg ccgcccgctc
     4921 gtgggcggtg cacggccagg ggctggcggc gttccgcggt gagcgcttcg cggacgcgtt
     4981 ggagctcttc gaccgcgcac tggcgatccg gcgcgagatc ggtgatccgg tcggtgccgc
     5041 gtggagcctc acgggtctgg gcatggcgta cggaggactg cgccagttcg acctcgccgt
     5101 cgaccggttc ggggaggccc tgcgcgggca cgtcgaggtc ggctcgtggt tcggcgaggg
     5161 cggcacgcgg ttgttcctga gcgacatcct gcgatcggct ggccagttcg aggcggcgct
     5221 cgagtcggcg cggcgcgcgc tcgagctgat ggactcgcac gacgctccgc acggcaaggc
     5281 gatggcgttg gtcggcatcg gctgggcgca gtcgaagctg ggccggcctg ccgaggggcg
     5341 cgactcgttc cggcaggcga tcgagttcct gcgcgtgctc ggcgaccgca agagcctcgc
     5401 ggaggcgttg cacgggctgg gggcgacgag cgcgggccag cccgaggtgg cgcgcacgca
     5461 cctgctggaa gcgctgacga tctacgagga ctacgaccac ccgctcacac ccgaggtgcg
     5521 ggcgaggctg cacgagctct cctaggggtg atcccggatg tgctcgcgct gatgtgtagg
     5581 cacactaccc atcatgcaga agcgcgctcg aacgctgttg gtgtggctgc acgtcgtgac
     5641 gtcggtcggc tggctgagtc aggcgctcgc actgttcacg ttgctgctct acgggctcaa
     5701 gaccggtgac gccgacgcgt tcaggatggc gcgggtgctg gaccaccacg tgctcgcgtt
     5761 catgggcgcc accagcgcgt tcagcggcat gatgctcagc gccacgacgc cgtgggggta
     5821 cttcaagcac tggtgggtgc tggggaagtt cgtgatcacc gtcgtgcagc tctacgtcgg
     5881 gatcttcgtg ctgagcggca ggctcgaagc cgcggcgaac ggtgacgtca gcgcgtggac
     5941 accggtcggg accgcgctca tggtcgccgg gttcgccttc cagacgtggc tcagcgtcgc
     6001 gaagccgtgg gggcgcacgc cgtgggcgga cccgaaggtc aagctgccca cggcgagcac
     6061 caaggcgttc gtgctggcgc tgacgatccc gttggtcgac ctcggtctcg ggctgtggat
     6121 gggcaacccg atgccgctga cgatgctcgt gacggtggtc gtctactcga tcaggcgggc
     6181 cgccaggggg aggcgccggt cgtcggacgc gtcgggtcgt ggaacttcgg cacgtccggc
     6241 tcgtcgaggc gcaacggcac caagccctcg gtgatcgcgg tcatgatccg ctcgtgggcg
     6301 cgccgggcgt cccccgcggt ctcggccctg aggtccgaca gctccaccgg cttgccgaag
     6361 tgcaccttga acgtcggccg cttgcgcacc gcgcgcagcc acgacgtcag gtacggcagg
     6421 acgtccctcc agccgctgac gctgaggttg ccccagtaga cggcctcgtg cgcgccccac
     6481 tggctgatcg ggacgaccgg gatgccgccg cccagcgcca tgcgggcgac gccggtcttg
     6541 ccgcgctcgg gccacaggcc ggggtcggtg ctgatcctgc cctcggggta cacggcgatc
     6601 gggtcgccgc ccttgttcaa cgcctcgacg gcccggtgca tcgcctcgcc cacgttcgcg
     6661 gaccggcggt cgacgcgcag gtggccgcac gccttgagag ccggtcccat gaccggcgcg
     6721 tcgagcaggc cgcccgcgag catgaaccgg gggttgacgc cgatcttgcg gcacgccgcg
     6781 atgaggacca tcgggtcgag gttgccgatg tggttggagg ccagcagcaa cggcttgccg
     6841 agcagttccg gcgggatgtc gcccgagacc tcgagcttgc cggtcagcgc gatcaggccc
     6901 cggtcgacca ccatgagcac gcgccagaag agcggtgtgg acacgcgggg cagcgtacgg
     6961 cgtgtcgtga ggacaccgtg cacgatccgg tgaaccatga gctttcgcac gcgtcccggt
     7021 tgcaaacggg gctggtgggg cgcgagggac taccttgtag acatggccgg gcgcacaggg
     7081 acttcgagaa agaccacgtc acgcggcaaa gcaccagcga agccgcgggc gcgttccacc
     7141 gcgtccagaa agcccgccgc gcgcaagagc ggcggtgcca tcagtgccgt gtggggtgct
     7201 ttggggcgtg gcgtcggaag cgtcgtgcgc accgtcagcc gcaccaagga cctggacccc
     7261 gaacaccgcc gtgacggcct cggcctcctg ctgatcgcgc tggcgttcat caccggcgcg
     7321 ggcgtgtggt ggcaggccgg gggaccggtc gggcagtggg tggacgtcgc cgtgcgcagc
     7381 tccgtcgggt tcccggcggt ggtcgtgccg gtcgtgctgc tcggcatcgg cgtcacgctg
     7441 atgcgcaccg accccaagcc cgacgcgcgg ccacggctga tcatcggctc gttcctgatg
     7501 atcatcggtg tgctcggcat gttccacctc atcggcggcc ttccgatgga cccgctcgaa
     7561 cgccgtgacg ccggcggcgc cctgggctac ctcgcgggag ggttcctcgc gcagggcctc
     7621 acgccgtggg tcgccgggcc gctgctgttc ctgatcttcg cgtacggcct gctggtcgtg
     7681 acgcacacgc cgatccgcca ggcgcccgaa cggatccgct cgctgctgca ccccggcaag
     7741 cccgccgagc cgtccccgtt cgacgaggaa gagcccgtcg aggagccgaa gccggtccgg
     7801 ctgcgccgcc cgtcgcgccg ccgccaggcc gtcgagcccg tcgccgcgga cgaaccgcag
     7861 gcggagctcc cgctggagga gccggtcgag cccccgccgc cgtccccgaa gccgtcgaag
     7921 aaggccgcgg ccgcccccgc cctggtcgtg cgcgcggtcg agggcgagta ccagctgccg
     7981 ccaccggacg tgctcaagga cggcgacgcg ccgaagaccc gcagcagggc caacgaccag
     8041 atgatcgagg ccatcaccgg cgtcctcgac cagttctcga tcgacgccca ggtcaccggc
     8101 ttcacccgcg gcccgacggt cacccgctac gaggtcgagc tcggccccgg cgtgaaggtc
     8161 gagaagatca ccgcgctgac caagaacatc gcgtacgccg tggcgacgga caacgtccgc
     8221 ctgctggccc cgatccccgg caagtccgcg gtgggcatcg aggtcccgaa cagcgaccgc
     8281 gagatggtgc gcctgggcga cgtgctgcgc gcgccgtcca ccgtcaagga cacgcacccg
     8341 atggtgatcg gcctcggcaa ggacatcgag ggccacatgg tcaccgcgaa cctgacgaag
     8401 atgccgcacc tgctggtcgc gggttccacg ggttccggca agtcgtcgtt cgtgaactcg
     8461 atgctggtgt cgctgctggc tcgcgcgacg ccggacgagg tccggatgat cctcatcgac
     8521 ccgaagatgg tcgaactgac gccgtacgag ggcatcccgc acctgatcac gccgatcatc
     8581 acgcagccga agaaggccgc ggccgcgctg gcgtggctcg tcgaggagat ggagcagcgc
     8641 taccaggaca tgcaggtcaa ccgggtgcgg cacgtcgacg acttcaaccg caaggtgaag
     8701 tccggcgaga tcaccgcgcc gccggggtcc gagcgcgtct accggcccta cccgtacatc
     8761 atggcgatcg tcgacgagct ggccgacctg atgatgaccg cgccgcgtga cgtcgaggac
     8821 gcgatcgtgc ggatcacgca gaaggcccgt gccgccggca tccacctggt gctggccacg
     8881 cagcggccgt ccgtcgacgt cgtcaccggt ctgatcaaga cgaacgtgcc ttcccggctc
     8941 gcgttcgcca cgtcgtcgct gacggactcg cgggtcatcc tggaccagcc cggtgccgag
     9001 aagctgatcg gcatgggtga cgcgctgtac ctgccgatgg gggccggcaa gccggtgcgc
     9061 atccagggcg cgttcgtggg cgacgaggag atctcctcga tcgtcgagtt caccaagaac
     9121 caggcccagc ccgagtacac cgacggggtc accgcgcaga aggccggcga gaagaaggag
     9181 atcgacgccg acatcggcga cgacctcgag ttgctggtgc aggccaccga gctgatcgtg
     9241 acgtcgcagt tcggctcgac gtcgatgctg cagcgcaagc tgcgcgtcgg gttcgcgaag
     9301 gcggggcgcc tcatggacct gctggagacc cgtggcgtcg tcgggccgtc cgaggggtcg
     9361 aaggcacgcg aggtgctgat caagccggac gagctcgaga acgtggtcta cctgatgcgc
     9421 ggaggcggcc ccgccgacga cgagtgacct acttcaggcc cgcctgctgg atgctcgtgg
     9481 ccgtcgagct cgcgctgccg ccgaactcgc gcacggccgc gtagtacagg tcggccgtgc
     9541 gcttgcacgc ccagctcgag ccgcactggt tgtacatgtc ggccttgaag ttgttgtcga
     9601 tgcgcaggcg gttcgcctcg ttccagcggg cctggcgctt gtagttgcgg tagccgaagt
     9661 cgtggcggtg gcacgtcggc aggaacttga agccgaaggg gttgtccggc gagtacgagc
     9721 agccgtcgga cgaccagtcg agctggtccg cgtcgggttg ctgggcgcgc agtgctgtga
     9781 actggctgag ggacttcgag tagaggtagt cgtcggtgac cgcgacgacg tccacggcga
     9841 gggccggggt gccggtgagg acgagggcga gggaggcggt ggctcccgcg aacgccgagc
     9901 gcagggtgtt cgacatggcg agctcctctg ggtgtgagca gggtctcgcc cagttgtagc
     9961 cggtggtcga ctgtcctcgg tagacacgat ctgatgaacg tcaggtgatc atgtgcccgc
    10021 aagcgattgc tgtggccacg cgaagttctc ggggcagccc cagcgagtgg agcatctcgt
    10081 tgtcggccac tccgcccagc aggtagccgc cgagcttctc ctgcgccagg cggaggcaga
    10141 tcgtctgcgc cgcggcgcct gcctcgatca ggccgaagcg gcccgcgcgt tcgccgtact
    10201 tctcgaacga gtccttgtcc gccagcacca gcacgatcgt cagcggtggt gcggacgggg
    10261 tgccgaggat ctcggccagg tcgtccggtg ccgggccgag gtcctgcagc gcgtggcggc
    10321 ggatgtcgta gcggaccgcg cgtccgtgga cgaaggcgta gcagcgcaac gggttcagcc
    10381 cgcccgcgga ggggacgctg tcgtcggaca gggcgcccag gaccgtgccg agctgcttgt
    10441 cgctcagcgg ttcaccggtg aactcccggg tgctcctgcg tgcccggaag agcttctgca
    10501 gccggtcgtt cgggcggggg agcgggaccg gggacgtggg cggctccagc gggtcgacga
    10561 gccgggacgg cgggcggaag tcccgcaggc ggtcgcccag cctgcgctgg tgcagcggtg
    10621 agaagcggct cgcggcccag aagtcgtcga acatcggctt caccccaggg gatgcggtgc
    10681 gggattgggg aacgcgcccg gtgaggcgtg cgggtagcgc cagtcgagct ccgcggcgcg
    10741 gccgcccagg tggggccagc ggtggtccga gtgcagcggg gccaggtccg gggacaggac
    10801 ccggacgcag tgcaggccca cggccgagag ttccggtgtg gtgagctcgc ggtaggcgag
    10861 ccggacgccc gcgcggtcga gggcgtgcac cagttcggtc agttcagccg tggtgccccg
    10921 ggcctgggcg tccggcggtg ggtccgcctc gaagccctgg aaccacggga ggtcgtccca
    10981 cttcgccgga tgcgtggcgt agtaggcggc gtgctcgtcg aagtcggtgg cctcctcgac
    11041 gggaccgtcg ccgttgcgag ccagccacac ctcgacgaag accgtgccct gcacccactc
    11101 ctcgtaggcc ttgcggaccg cctccgcggt cgtcgcccgg caggccagtc cgagcgtcgg
    11161 gcgggacctg ccggcgatcg ggagcgatcc cgccacggcg accaccgggt gcgggctgta
    11221 ggccggggtg aggtcgaacg cctgggcgcc gtgcgggagg tcggcgtcga accgttgtgg
    11281 tgcaagggaa tgcagccagg tcgtggtgaa cgcgtcgcgc tccaccagtt cctggaccgc
    11341 gcgcagcagt gcgctggtcg tcgacgcgcc cgccgccagg ccggacgagg tcgcgggcag
    11401 gccgtaggac gcgtccaggg ccacgaggcc ggcggggacg cggatcgggt cgtttcccgg
    11461 gagcgtccac gcccgcgtgt acggggtgtc gacgtatccc ttgcggtagc ggtagttcgg
    11521 ggccacccgc tgttccacgg tgtgcaggct gaagtgttcg agcggccagc actcgccctc
    11581 ggtgacgacc tccagccgtg cccgtgcggc ggcgtggcgt tccagggcct cggcgatcgc
    11641 ggcgaccctg gtggtgccac cggacgtgcc acccgtcgcg aacggctcgg gcaccgcggc
    11701 ccagccttcg aggtccacat cggacaggct gtgcggcacg gggtgcagtt gcgacaccac
    11761 cccctgccgc cagccgaccg cgcgctcgac cagcgcctcc gccacggtcc tcatcgcttc
    11821 ccccggtacc gccggaagat ccagtacccg agagccagcg ccccgccgac gtagagcaca
    11881 ccgaccaccg ccgcgacacc ctcgtccacg gaggcgatcg gtcccagcgt gaacagcacg
    11941 acgaacggtt ccaggaacca caggacggac cagccgagca accggaccac gctgcccacc
    12001 ggattcggcg acctggcgag gaaaccggag gcggcggccc acgcgagcgc cgccgcgaag
    12061 ccgccgagcc accagcccca gtgcaggtcg aagacagcgc ccatcgtggc gaacggcagc
    12121 acgacgacca gcaacgggaa gatcgcggcg ggcaggacga gcaggctgcg aggtcgcggg
    12181 aggtcctgcg tctcccggtg cagcgccgcg gggatgtgca cggccgcgcc gaccgaggaa
    12241 accgcgcagc agcaacaaca acagcaacag gtgggcgtcg cggcgttcgc ggcggccgca
    12301 cccggtgaga actggtcagg taaccgcact gccgtcgcgt tcatggttcc cccaaggaag
    12361 tgacacgcgc ccgaactcga ccgtcgggca gacttcgcag ccggcggcgg gcagcacgct
    12421 ctcgcgcgtc gtcgtgaact cgtccaggtg gacggtgacg accgtgtcga gcaacgccag
    12481 cgagccgtcg cggatgttct gaaccgcttg cagggcaagg gagatcggga actcgtagga
    12541 cgtcgccgcc gggtgcggcg gaggcggcgg atccccccac cgccgccccg cccgcaccgc
    12601 gaggcacgcc aggcacgcgc cagcaccggg caccacgaag ggcccgacgg cggcggtgtg
    12661 gtggtacgcg aggtccagca acaggtgcgg gacctccgtc tcgcgcgcca cctcgaccag
    12721 gtcgaccaac gtgccggtgg tccgcacgac gagcaggagg tccgggtcct cgtcgtgcgg
    12781 caaccgctct accagcccgg cgggtgcctc cccgacgacg cgcgtgccga cccccatcgg
    12841 cttcttcgcg tcgccggtgg gcaacccggc cgggcggaga gcgcccaggg tcctcagctg
    12901 ggccacgtgc tggcgaaccg gttcccccaa ccggttctcg tcgaccgttc gagccgctcc
    12961 cctcaaaacc ggctcgaaca gtcccgccag cgccacggcc accgccctgg gcaggtccgg
    13021 gatcaggtac gcgagatccg cacccgcgta aacgacaagg ccttcgtctc gaacctgggc
    13081 gtgccaggcg ggatcagcga ccaggctcat cctcgtcccc ccgtttcagg aagttctcga
    13141 tctcctgctc gctcggcagg tcccccgccg ggtccatgag gttctcggcg atcggcggca
    13201 agggctgctc ggcccacgcg ggctggtagt cgtcgctcgg cagcaacccg tgccgtgacg
    13261 cgaactcctc ggccgcgtcc cggatcgact cccgcagcgt ccccaccacc gcggtctccg
    13321 ccgtgtacgt cagctcgacc agcaacgccc gcacgttctc gagctggttc tcgtcgcctg
    13381 ccttgcgcgc gagctcgggc cagaactgcc gctcgaacaa ccgcacgaag tccgccgcca
    13441 ccgcgtcggt cgccgtgcgc aggcgcgtga agctgtccat gacgtcatcg ctgggcaccc
    13501 gtaggccggc caaccggccg cccgcttcga gtgcccagcg acgcgcgtgc ggccagccgt
    13561 acttccaccg caccaaaccc aaccgcatag cccggaggag gagtcgcggt tggacctcac
    13621 ccatcggaac gaggtgccgg atgtcgcgca ccttgatccg aacccagtcg tcgggcccct
    13681 cggtctcgcc catgccgagc accgcggcga ccgactcgcc cttttcgcgt gccgagatca
    13741 gttccgcgat cgcgggcagc gagaaccccc gctgctgcaa ccgctgcacc aacgtcaacc
    13801 gctcgacgtg cgaggcgtcg tagtacgcca cgcgcccctg ccgtctcggc gcgtgcagca
    13861 cacccttcgt ctggtacatg cgaatggtgc tgctgggcag gccgatccgg gcggcgagct
    13921 cgtcgacggt gagcgattcg ggcacaggag tgatcctggc gccggcgggt tcgtcgagtc
    13981 aagactcttc gagtaattac tcgaagagtt acaactccag gagcatccgg ctgttgccga
    14041 gcgtgttcgg cttcacgtag ctcaggtcga ggaactcggc gacgccctcg tccaccgacc
    14101 gcatgatctc ctcgtagacc tcggggctca ccggcgtgcc ctcgatctcg acgaagccgt
    14161 gcttgttgaa gaacttggtc tcgaacgtga ggcagaagat ccgcgcgagc tgcagctcct
    14221 tggccgtcgc gatgagctgc gccacgatcc ggtggcccac gcccttgccc agcgccatgg
    14281 gggagaccgc gacgctgcgg atctcggcca ggtcctccca catcacgtgc agggcgccgc
    14341 agccgagcag ttcgccgtcc tcctcggcga cccagaactc ctggaccgcc tcgtacagcg
    14401 tgaccagggg tttggccagg agcaccttgc ccgcgtaccc gtcgatcagc gccttcatgg
    14461 cgcgcacgtc gctggtgcgg gcgcgccgca cgactacccc actggtcaca accgtcaagt
    14521 atgggccgcg cccgcacggg gctcgcgggc agaggtgggg gtggccgggc agcgcgattc
    14581 aagcgcccag acctggggcg gttacgctga gcgccgtgtc ttctcccacc actccgcgac
    14641 gcgtgtcgct gctgaccctg ggctgcgccc gcaacgaggt cgactccgaa gagctcgccg
    14701 gacgcctcgg cgagggcggc tgggagctgg tggacgaggg cgctgacgtc gtcgtcgtca
    14761 acacgtgcgg cttcgtcgag caggccaaga aggactcggt cgacacgctg ctcgccgcgt
    14821 ccgacaccgg cgccaaggtc gtcgccgtcg ggtgcatggc ggagcgctac ggcaaggagc
    14881 tcgcggacag cctccccgag gcggccgcgg tcctcgggtt cgaccagtac aacgacctgg
    14941 ccgagcggct gcaggacgtg ctgcacggca agcccgtcga gtcgcacgtg ccggtggacc
    15001 ggcggacgct gctgcccatc acgccggtga agcgccagga ggccaaggac gcggtgcagg
    15061 tgcccggcca cggctggggg cccaccaata cgccccgcaa gcgcctcgac gacgccccgg
    15121 tggcgccgct caagatcgcg tccggttgtg accgccggtg cagcttctgc gcgatcccga
    15181 gcttccgcgg cgcgttcgtg tcgcggcacc cggacgagat cgtgtccgag gccatgtggc
    15241 tcgccgagaa cggcgtcaag gagctgttcc tcgtcagcga gaactccacg agctacggca
    15301 aggacctgcc gcgtgagcag ggcgccctgg agcagctgct gccgcgcctg gcgtccgtcc
    15361 ccggcgtcga gcgcgtgcgg gtgagctacc tgcagccggc cgagaccaag ccgagcctgg
    15421 tcgccgcgat cgcgaagacc gacaaggtcg cgaactactt cgacatgtcg ttccagcact
    15481 cgagcgagaa cgtgctgcgc cgcatgcgcc ggttcggtga cacggacagc ttcctcaagc
    15541 tcgtgtggca gatccgcgag cacgcgcccg aggccggcat ccgcagcaac ttcatcgtcg
    15601 gcttccccgg tgagaccgag gccgacctgc aggagctgga gcggttcctc accgaggcgc
    15661 ggctcgacgc ggtcggcatc ttcggctact ccgacgagga cggcaccgag gccgaggagc
    15721 tcgacggcaa gctcgacgcc gacgtgatcg cggagcgcgt gcagcgcatc ggcaacctcg
    15781 tcgaggagct caccagccag cgcgcggagg accgggtcgg caccgaggtc acggtgctga
    15841 tcgagaccga ggaggacgac gagaacgact gcgtcgggcg cgccgagcac caggctcccg
    15901 aggtcgacgg cgagtgcatc gtgctggagg cggagggcct caggcgcggt gacttcgtgc
    15961 gctgccgcgt cgtcgactcc gagggcgtcg acctgatcgt cgaggtagtc ccgacatgac
    16021 cgaggcccgg aaggtcccgc tgctcaacgt cgcgaacatc ctcacgatgg cgcgactggc
    16081 gctcgttccg gtcttcctgt tctccctgtt cgaagcgggt ggcttcgaca ccacgtggcg
    16141 cctcatcgcg ttcgcgatct tcgcgatcgc gagcttcacc gaccacatcg acggcacgct
    16201 cgcgcgcaag cacgggctca tcaccgactt cggcaagatc gccgacccca tcgcggacaa
    16261 ggcgctcacc gggtccgcgc tggtggggct cagcatcctc gacgtgctgc cgtggtggat
    16321 cacgatcacc atcgcggtgc gcgagatcgg catcacgctg ctgcggttct gggtgatccg
    16381 ctacggcgtc atcccggcca gccgcggcgg caaggccaag acgctcgccc aggtcatcgc
    16441 gatcgggctg ttcgtgctcc cgcagaacga cgtgctgggg ctcatcgcct gggtgatcat
    16501 ggccgtcgcg ctcgtgctga ccatcgtcac gggaatcgac tacgtgatcc acgcgttcaa
    16561 gatgaaggcg agagcaggca gggcggtgct gtgacaggcg tcgtcgagct gctcgaagcc
    16621 aggaacgaga ccgtcgccac ggccgagtcg ctgaccgcgg gtctgctgtg cgcgacgatc
    16681 gtcgacacac cgggggcgag tgccgtggtc cgcggtgggt tgatcgtcta cgccaccgag
    16741 ctcaagcacg agctcgcggg cgtggaccag cagttgctcg acgagcacgg tgccgtgcac
    16801 cccgacgtcg cgatccaact ggccgaaggc gcccggacga ggtgcggagc ggactggggg
    16861 atcgggctca ccggggtcgc cgggccggac ccgcaggacg gtgtcgctcc ggggacggtc
    16921 cacatcggct tgagcgggcc tggagtgtcc acagtgcgga caatcacgct gagtggtgac
    16981 cgcgcagctg tccgttcggc tgccgtggaa aaagccctgg tcctgctgtc ggacacgctg
    17041 ctggccgtcg actccgggaa caaatgatga ctccgcgttc gttcgccctt ggcggacgtg
    17101 ttcggaagtc agtgcccgtt gtcggtgtcg atcggtaacg tagggacacg gccggccgga
    17161 aggaggcgcg cgatgaccgt gctgctgcgc gaggcgatcg gtgatcggct tcgccatgcc
    17221 cgcaccaacc aacgccgcac gctgcgcgag gtctctcgga ccgcccgcgt gagcctgggg
    17281 tacctgtccg aggtggagcg cggccgcaaa gaggcgtcca gcgaactcct cgcggccatc
    17341 tgcgaagcac tggaactgcc cctgtccgag ttgctgcacc acgtcgcctc cgacatcggc
    17401 gccgtccagc agacgccgga cacggtgccc gacaccgtcc cggacggtcg atcggagcgc
    17461 gggaagctgg agggtggccg cgtgctgccg tccacgctct cggacgacct gtccgacctg
    17521 cgcctgcagc ccatgctcac gcaccggctc acgagcaaga tcggcgagac gcccaaggca
    17581 gtcgtcgcgg cctgatccca tgtcctccac cgaccccgtt cgccccgtgg cgagcggggt
    17641 cgcctgcatt cgggtgaacg tcaccgggct gtggcccccg acacgtgacg gtctgcaaca
    17701 actcggaccg ttcgtacgtt caacacacaa cagacccggc gtgttgaacg acaggcaacg
    17761 gcttggcatc ggcacgctgg gtcaccgcgt cccagggcgc gggtgcgggc aggattggca
    17821 cgtcgtccga cgtgttctcc taagtcccgg ggtgggtcag ggtgttcccg gatatctccc
    17881 cgtgtcggtg gatacgccga cgcacaattg agacgatgga tccaacaccg gcaccgagaa
    17941 ggcaggcgta ggagatggcc agtccgttcg tgaagttctg gaagtacctg atggcgtcgt
    18001 tctcgtcgaa gatcgacgag cacgccgacc ccaaggtgca gatccagcag gccatcgagg
    18061 aggcgcagcg gcagcaccag gcgctctccc agcaggctgc ggccgtcatc ggcaaccagc
    18121 gccagctgga gatgaagctc aaccgccagc tcggcgacgt cgagaagctg caggcctccg
    18181 cccgtcaggc tctggtgctc gccgacgagg cgcgcgcgaa gggcgacgag cagaaggcca
    18241 cccagttcga gaacgccgcg cagggcttcg ccacccagct cgtcaccgcc gagcagggca
    18301 tcgaggacct gaagacgctg cacgaccagt cgctgcaggc cgccgcacag gccaagcagg
    18361 cggtcgagcg caactcgatg atgctgcagc agaagctggc cgagcgcacc aagctcctca
    18421 gccagctcga gcaggccaag atgcaggagc aggtctccgc gtcgctgaac cagatgagcg
    18481 agctcgcggc gcccggcaac gtgccgtcgc tggaagaggt tcgcgacaag atcgagaagc
    18541 gctactcgac cgcgctcggg tccgccgagc tggcccagaa ctcggtgcag ggccggatgc
    18601 tcgaggtgca ggcctcgacc acccagctcg ctggttcgtc gcggctcgag cagatccgcg
    18661 cgtccatgca cgggggccag tcgagcaccc cgcagcaggt gacggcgggc aacagcgcgg
    18721 ccgcgcagat ccaggccgag atcgcgcagc gcgtccagtc ggagcagaag acccagcagc
    18781 agcaggttcc tcccgcccag aactgacgtt ctgaggccgg gggagcagga ggagtcagca
    18841 ggtgatcatg gagccctgga gaaaccgtcc caacaacgag atcgtccgca aggtcgtcgg
    18901 tgagttgggt gcgtcgctcc agggccaccc gctggccgag caggcgcgct accgcctgca
    18961 gaagtggaac gacccggtcg ccaagctcga acgcaagcgc aagcgcacca acgccgtgct
    19021 gacgttctgg ctgatcgtga tctcgatgct cggcacgctc gccgtgctgg gcttcaccgg
    19081 cgtgctcggc acgtgggccg ccgtcaccgg ctcgatcggt gcggccgtgc cggccgtcct
    19141 ggccgtgcgc agcgggttca agctgaagga gctgggcgtc gcccggcagc ggctggcgtt
    19201 gtcgccgccg cctcggcccc ggccgccgct gcccgcgcac atctcgtccg cgcgcgttcc
    19261 gatggagaag ctccacagcg ccgaggacgc gatggcccag ctgctcgtgc agctcgactc
    19321 gcccgcgctg acctcgatgc cgacggagtc cgtccagcac gcccggcaga ccgcccagga
    19381 ggccgccacg gccatccgcg cggtgtcggc gcagctccag gccgtcgaac gcgctcgcga
    19441 caacgcaccg ccgctggagc gcgcgcccct ggtcgagggt gttcgcgtgc tcaggatcca
    19501 actggcggac ggcgtggacc gctactgtgc gctggtggcc gaggcgggca aggccctcgc
    19561 ggcgagcacg cagttccaga accccggcga ggtgctggac gacgccacgg accacatggc
    19621 gggtctggcg tccgctatgc gtgatgtctc aggctattca gcgcattgaa tgtaacgctc
    19681 ggtaatcgtg tgccgctatt cggcgagtct ctctggagat ctttgctgca atcgtgtgat
    19741 tatcggactg ttatctagcc gtggccgcta catggcgtgg caggatctcg gggccggtct
    19801 gcgggaagtc cggctgaatt gccgggaggc agtgcgttgg cgttgtggac cgtgcacggg
    19861 gacggtcgga tcaccgacag tgaaaccgtc gcaccccagg agagggtgag ctggccgctc
    19921 accatcgggt tcggagttca gcacctcgtc gccatgttcg gcgccacggt gatcgtcccc
    19981 accgccaccg gcctccccgt cgccaccacg ctgctgttct ccggtctggg cacgctgctg
    20041 ttcctggtga tcaccaagaa ccgggtcccg agctacctcg gctcgtcctt cgccttcgtg
    20101 gcgccgctgg tggccgcgcg cgagcagggc atcgcggcgc agctcggcgg tgtcgtcgcc
    20161 gcgggcctgc tggtgatcgt cgtcggcatc gcggtcaagg cgctcggcgt gcggctgctg
    20221 gagtcggtca tgccgccggt cgtcaccggc gccgtcgtga tcctcatcgg cctcaacctc
    20281 tcccgtcagg ccaccgcgaa cttcggtgag cagccgttgc tggccgccct gacgaccgtg
    20341 gtgatcctgc tggccggcgt gctgggcagg ggcctggtgt tccggttctc gatcctgatc
    20401 ggcttcgtgg cggtctggat gggcgggctg gcgttcggcg ccgtgccgtc cgagcggatc
    20461 gccgcgctgc gcgaggcggc ctgggtgggc ctgccgaagc tgtaccagcc cgaactgcgg
    20521 ccgtccgtgg tgctgctgat gctgcccgtg gtgatcgtgc tggtcgccga ggtcgtcggg
    20581 cacgtgaagg ccgtcgcggc gctgaccggg cgcaacctgg acggcagcgc gggggacgcg
    20641 atcatcgcga acggcctgtc gactgcgctg tcgggcctgg gcggtggcgc cggcacgacg
    20701 acgtactccg agaacatcgg cgtgatggcg gtgacccgcg tctacacgac ggcggcgttc
    20761 gcgttcgcgg gtgtgttcgc cacgctgctg gcgttctccc cgaaggccat cgcgctgttc
    20821 ggcaccatcc cgccgggcgt gctcggcggc tgcacgctgg tgctctacgg cctgatcgtg
    20881 ctgatcggcg tgcggatctg gatggatcgc ggcgtcgacc tggcgagccc cgtcaacgcg
    20941 atggtcggcg gtgccgccct ggtggccggt gtcggcgacc tgaccgtcga gatcggcgac
    21001 ctcgagatgg gcggcatggt ctggggctcg ctgctcgtcg tgatcctgca ccccgtgatg
    21061 cgctggctgc gggccgcgcg gcgcagctga ggcgtccaca ccttcgtgtg gttttgttcc
    21121 ctccacttcg gaccgatact caagttgatc ttgcaccgct cgcggtcgtt gtccttgggt
    21181 gccaacgacg cgggtcgtga tcccggcgcg cgaagaggag ccgcgcgtcg cgcgagcggt
    21241 gctgtccgtt gtggacggcg cgctaccgca gcgccctgtt gatccgcgac accagcccgg
    21301 ggccctcgta gatgaacccg gtgtagatct gcacgaggct cgcgccggcg tcgatcatgc
    21361 gcttggcgtc gtcggcggtc gcgatgccgc ccacgccgat gaccggcagg tcgctgttct
    21421 tcgtgatgaa ccggaccacg tcgttcgcgc gccgggtgag cggcctgccg ctcaggccgc
    21481 cggtctcgtt ctgatgcgcg ctcgtgaggc cctcgcggct gagggtggtg ttcgtggcga
    21541 tgaggccctt gatgccgttg tcgacgcaca cctggatgac ctcggcgatg gcgtcctcgg
    21601 tcaggtccgg cgcgatcttg accagcatcg gcttggtcgt cgccttcgtc agctccgcga
    21661 cgagctcggt cagcgcgccc ttgtcctgca ggctgcgcag gccgggagtg ttcggcgagc
    21721 tgacgttgat ggcgtagtag tcgccgtggt ccttcagcgc gttcagcgag ttcaggtagt
    21781 cctgcacggc gtcctcgacc ggcgtgacct tggacttgcc gaggctgatg cccagcgggg
    21841 ccttgagcgg cgtgcggtcg agcttcgcgg caagcgcttg cgcgcccgcg ttgttgaagc
    21901 ccatccggtt gatgatcgcc tcgtcctcgc gcaggcggaa caggcgcggt ttcgggttgc
    21961 cgggctgtgc gtgccaggtg acggtgccga cctcgacgaa cccgaacccg agcgcggccc
    22021 acaccggcag cgcgcgcccg tccttgtcga ggcccgccgc gagccccacc gggttgggga
    22081 agcggacgcc gaagacggtg cgcgggttgt tctggccgcg ggcgaacctc gccagcgggc
    22141 tcagcctggc catgacgtcg agcgtggtct cgtggacccg ctccgcgtcg ccgccgtgca
    22201 ttccgaacaa cgccctgcgc accacctgct tgtacaccac gcgcccaccc tataacgcca
    22261 gctcagggta gtcgccgtca catcgtcggc ttggccacct tgatcgtcgc ctgctcgtcc
    22321 aacggcatct tgggcttcgc gaggaacgtc accggcagcg cccgcaaccc ccggctcccg
    22381 agcgacaccc tccagccgag cggctgcgac gtgtccaggg cgaggcccgc gcagcgcccc
    22441 agcaacgtcc ggaacgcgat ctcgccctcc agccgggcca gcggcgcgcc caggcagaag
    22501 tggatgccgt ggccgaacgc caggtgctgc cggtccgccc gctcgatgtt gagctggtcg
    22561 gcccgcgggt agcggttcgg gtcgtgctcg gccgaggcca gcgacagcag cacgacgtcg
    22621 cccgccggaa tctgcacgcc gccgatcgtc agcggtttcg tggcgaaccg caccacgtgc
    22681 gaggtcggtc cgtcgaaccg caggaactcc tcgatcgcgc cgggcagcag ggacgacgag
    22741 cgctgcagca gttcgagctg ctcggggtcg cgcagcaacg ccagggcgcc gttgcccacc
    22801 aggtcgacgg cggtcgtgta gcccgccacg agcagcagga acgcgagcga ggcgagttcg
    22861 tcgtcggtca gcgcggtctc gccggtcgcg cgggccaggc cgccgatcag gtcgtcgtcg
    22921 ccggaggttc gcttgtgcgt caccaggtcg cgcaggtagt cggaggtctc ctcgcgggcc
    22981 gaggccgcgt cgccgtccgc gaggccggtg accacgtccg cccagtagcg gaagttctcc
    23041 tggtcgacgg cgggcacgcc gagcagctcc atgatcacgg cgatcggcag cggcgccgcg
    23101 aagtccgcga tcaggtcgca gcgtcccgcg tccgcgaagc cgtcggccag ggacgcggcc
    23161 acctgctcga tgcgggggcg cagcgcggcg atgcggcggg gcgtgagctg gctcgacacc
    23221 gcacggcgca aacgcgtgtg gttcggctcg tcgctgttca tcatgtggtc ggacaggtcg
    23281 ccgaaccacc acgacgcgaa gtgcggatgg ccgcgcaggg gttcggcgag cgcggagccg
    23341 tgggaggaca gcagcgggtt gtccaacgcg gcgcgcacgt cggggtagcg ggtcacgagc
    23401 cacatcggca cgccgagggt ctccacccgg tgcacgggac cggcgtcgcg caggctcttg
    23461 agcaccgcgt aggggtcgtc ggtgaagccg gggcgcaacg catccagatt taccgccata
    23521 ttggggcaca cggccgggag agcgtctcgg ttcaaccgga ttggcatttt ggacagaagt
    23581 acacgaatct gccgtcgatc tcgtccgatc ggacccttgt gcgacaccgc aaacagggtt
    23641 tgccggtccg ctcgaaaacg tagtgctgca cgcgcaggtc gccggtcgtg ctctgctcgg
    23701 gccgccactg gttggcctgc aacagcttcc gcgagagcgc aaccgcacgt gaggcgtccg
    23761 cggcggacac cggggccgtc ggcagaacgc gcaacaggaa acagacttcc gcgcggtaga
    23821 gattgccgac gcccgccatc acgcgctggt ccaacaatgc gagaccgatc ggccgggaag
    23881 gggccgcggt caaccgccga acggcctcag cgctgtcgaa gtcgggggcc aggagatcag
    23941 gtccgaggtg ggagatcaat cgatcttcct cggcggtcgg cacgaactcc atgtcgtgca
    24001 gcgcgaatcc gatggcctgc cggtcgtcca cctcgaacac ggcgcgggcc tggtgcgcgg
    24061 gacgccgcca gcgctcaccg ggccggtaga ggtgccacga gccgtccatg cggaagtggc
    24121 tgcgcaggct gttgccgtcg gagaagtggg tgaacatgtg cttgccgtac gtgcgcacgc
    24181 cgagcacgtc caggcccgcc aggtccagcg cggccagccg ggggtggcgc agttcgccgc
    24241 gccgcagcgt cttcccggcc agcgcctcgt tcatgcgatg accggccagg aagaccgtgt
    24301 ccccttcagg catccaccgc ttcctggatc tcgtcgtcgt cgaagtcgtg gtgcacggcc
    24361 cggcgccggc tccgcgagat gcgctggatg cgggcgagca gcaggttgaa cgccagcgcg
    24421 acctctcgtg cgcccggagt accccactcg tggatcggca tgcatgcgcc ctgtgcctgc
    24481 tgcacggcga gacggtccgg caacgccacc ggcatcacca acggcccgaa gatgtccctc
    24541 agctcgtcga tgcggaactg gtgctcgtgc gagcgcggac gcacgcggtt caccacgaca
    24601 ccgagcggct gcaggtcggc gttgttgctc tcgcgctcgt tctgcaccgc ctcgaacgcc
    24661 cgctgcacgc ccgccacggc gaacatcgtc ggctcggtga ccagcagcgc gcggtcggcc
    24721 gccaccagcg ccgagcgggt cagctggccc agcgacggcg ggcagtcgag cagcacgagg
    24781 tggtacggga actcgtcgta catgtcccgc aacgtgcgca acgcgtcttt cagccggtgc
    24841 agccgcgact cgcccgggtc ggggtggttg agcagctcgg cgtcctcgga cccggacagc
    24901 acgtcgatgc cgtcacccca gcggctgggg cggatcgcct gttccaggtt ctcctcggac
    24961 gggtcctgca ggacgtcgta gatgctcgcc ttggactcct ctggctccag cgtcgacgtg
    25021 gcgttgcact gcggatcgag atcgatcacc agggtgcgga caccacggcg gagggcggca
    25081 gaggccaggc cgagcaccac cgtcgtcttg ccgacgcctc ccttgaggct gagcacggac
    25141 accgtatgca cagacctact ctagggtctc ctactctgtt ggccatgcga ccggacgccg
    25201 tacacagggt gctcgacgcc gaattggccg ccgcacgcga gcgcaggggt gggcaacacc
    25261 cccgcgtgct cgacgtcgga ggcggcagcg gcgtgtgggc cgtgcccctc gccgcagcgg
    25321 ggtgcgccgt cacggtcgtg gagccttctc cgaacgcgtt ggcgacgctg aacacccgtg
    25381 cgcgcgaggc cggggtgacg atcaacgccg tccagggcga cacggacgca ctgggcgttc
    25441 ccgccggtga ggccgatctg gtgctcgcgc acgggctgct ggaggtcgtc gacgacgccc
    25501 cggccgcgct cgcctcgctg gccgccgcgg tcgcgccggg cggagcggtc tccgtggtgg
    25561 tcgcgaaccg gttcgcggcg atcctgcacc gcgcgatcgc cggtcgcatc gtcgacgcgc
    25621 ggcggttgct ggacgacgac gcgggccagc tcgcgggcac gcgcgacccg ttgcagcgcc
    25681 ggttcgacgt cccaggcctt gagaagctcg tcctggaggc cggactctcc gtcgaactgc
    25741 tgcaaggtca tggcatcgtt gcggatctcg tgcccggtgt ggtgctggac gcgaatccgg
    25801 gtgccgccga cgcgctcgcc gagctggaac tggccgccgc gaccagatcc ccgctccggg
    25861 acgtcgccgc ccggctgcac gtgctcgccc gccgtaccgc ctgacagcgt ttgcattcgg
    25921 gacttttatg accctgatga gtggtcccaa acaacgccgg ggcgaaagat aatggcttcg
    25981 ctgccgacgt agggatccga cgcgatggaa agttccgac
//
