LOCUS       NZ_CP099738            22115 bp    DNA     circular CON 27-AUG-2024
DEFINITION  Lentzea sp. HUAS12 chromosome.
ACCESSION   NZ_CP099738
VERSION     NZ_CP099738.1
KEYWORDS    RefSeq.
SOURCE      Lentzea sp. HUAS12
  ORGANISM  Lentzea sp. HUAS12
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 9676923)
  AUTHORS   Ping,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JUN-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024125735.1-RS_2024_08_27
            Annotation Date                   :: 08/27/2024 06:34:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,161
            CDSs (total)                      :: 9,080
            Genes (coding)                    :: 8,988
            CDSs (with protein)               :: 8,988
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 21 of 92
            Pseudo Genes (incomplete)         :: 77 of 92
            Pseudo Genes (internal stop)      :: 3 of 92
            Pseudo Genes (multiple problems)  :: 8 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:47:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5746581
            Orig. end                         :: 5768696
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP099738.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Ping Mo.
FEATURES             Location/Qualifiers
     region          1..22115
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="28"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22115
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22115
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12115](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12115)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    8..24
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.43"
                     /tool="antismash"
     misc_feature    15..29
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.28"
                     /tool="antismash"
     gene            complement(1286..2128)
                     /locus_tag="ND450_RS26005"
                     /old_locus_tag="ND450_26005"
     CDS             complement(1286..2128)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159536.1"
                     /locus_tag="ND450_RS26005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_26005"
                     /product="ECF transporter S component"
                     /protein_id="WP_253321254.1"
                     /transl_table=11
                     /translation="MADGRGRRGGTVIAIRRRSAVALTLSGVIGLAAFTWPLVIAPSSD
                     IARGGDAPWTFALLLPLVLAVVLAELSDKGMDSKAIAMLGVLSALGAAIRPLGPGTAGI
                     ETVFFLMVLGGRVFGPGFGFVLGNTTLFASALLTGGVGPWLPFQMLGAAWVALGAGLLP
                     QWRGRAEIALLASYGVVSSLVYGFLLNLSFWPFAVGEGTSVSFDPNSSPGTNLVRLAAF
                     TLATSLGWDLMRAVTTAVLVAVTAPVLLRTLRRAARKAAFEPVPNKELAQTIDDKRDA"
     gene            complement(2092..3648)
                     /locus_tag="ND450_RS26010"
                     /old_locus_tag="ND450_26010"
     CDS             complement(2092..3648)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013230735.1"
                     /locus_tag="ND450_RS26010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_26010"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_253321255.1"
                     /transl_table=11
                     /translation="MIRFEDVTITYAERPVLAHLSLEIPEGELCLVVGRTGSGKSTFLR
                     AINGLVPHFSGGTLAGRVLVDGRDTATHPPRELADVVGFVGQDPLAGFVADNVEDELAY
                     SMESLGLPNDVMRKRVEETLDLLGLAALRDRPLATLSGGQQQRVAIGAALTAHPRVLVL
                     DEPTSALDPGAAEDVLAAVQRLVHDLGMTVVIAEHRLERVAQYADRALLLPQGELGEVG
                     EVLTRSPVAPPVVRLARLAGWTPVPVSVRDARRQAASLRARLPEPATEPVRKAEPVLEA
                     RDVVVRYGEVQAVRGVSLTAGKGERIALMGRNGSGKSSLLWAVQGSGKRTSGTVAVGGT
                     DPKALKPAERRRTVALVPQQPSDLLYLETVAEECAQADTETGRPAGTCRALLDGLVSLE
                     PQAHPRDLSEGQKLALVLAVMLTGTPDVLLLDEPTRGLDHPAKEALAKVLHDLPTTTVL
                     ATHDVEFVAEYATRVVVMAEGEVVADGPAREVVTSSPIFAPQVSKVLGPWLTVADVEAA
                     L"
     gene            complement(3645..4676)
                     /locus_tag="ND450_RS26015"
                     /old_locus_tag="ND450_26015"
     CDS             complement(3645..4676)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681366.1"
                     /locus_tag="ND450_RS26015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_26015"
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="WP_253321256.1"
                     /transl_table=11
                     /translation="MRLHSGAWWLWALGLATAASRTTNPLLLGLVLAVAGVVVVTCRAT
                     TPWAGTYGVFLKFGLLVIGLRVLVHALLGGVTGPTVLFTLPQVPLPDWAQGIRVGGPVT
                     AEGMVFALYQGLLLATILSCVGAANALANPKRLLRSLPAALYEVSVAVVVALTVAPQLV
                     ASARSVRRARQLRGDTAKGPRAIRTMLVPVLEDALDRSLVLAASMDSRGYGRTAGISRR
                     DRAWTGALVLAGLAGICIGTYGLLAGAYTGWPLLAVGGVLAVAGLKVGARRVPRTRYRP
                     DRWTPTAIAVAVSGVAGAVVLVFSADPALSPSTVPLQAPELPLVPAIGVLLALAPVGLV
                     RER"
     gene            complement(4711..5481)
                     /locus_tag="ND450_RS26020"
                     /old_locus_tag="ND450_26020"
     CDS             complement(4711..5481)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS26020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_26020"
                     /product="hypothetical protein"
                     /protein_id="WP_253321257.1"
                     /transl_table=11
                     /translation="MRRLFVALALVAAFVPVPASAAGCDGVTVVVDYRGLGGGVQQGCA
                     PGSPSSGVAALTAAGFGYTYASRQAGFVCRINGRPGTDADKCVSASPATAYWSYWHAPA
                     GGAWTYSNQGAATYVPARGTVQGWSFGAGEQPGIAPPAAPAPPQPPVRQPPAPQPPAQQ
                     PPAQQPPAQTTTAPPPSSSSVAAPSSVVPASSAEVSSVAAGETSAPAVAEKSRQVEEKP
                     GLGWVWTLLAVLVIAALVVAGLLVARRRRAVEDE"
     gene            complement(5478..5891)
                     /locus_tag="ND450_RS26025"
                     /old_locus_tag="ND450_26025"
     CDS             complement(5478..5891)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS26025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_26025"
                     /product="hypothetical protein"
                     /protein_id="WP_253321258.1"
                     /transl_table=11
                     /translation="MRRLLAVLALVAGSFAATSPASAASCAGVEVVVDFGSLGGGVQTG
                     CAAGDPATGLTALTGAGFTYSFVPRQPGFVCRINALPNPCTVPTTSAYWSYWHASPGGT
                     WSYSTSGASGYDPAPGSVEGWAFGAGVAPAATP"
     gene            complement(5891..7090)
                     /locus_tag="ND450_RS26030"
                     /old_locus_tag="ND450_26030"
     CDS             complement(5891..7090)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019298.5"
                     /locus_tag="ND450_RS26030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_26030"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_253321259.1"
                     /transl_table=11
                     /translation="MIRRSALVAVMATALVVTPQAQAAEPPSAGTWLAAQFADGDHLLQ
                     GPGIVDPGLTADGVYALAAAGVGKSTAVKAAAWLAQPDQLSFLIGDGETESYVGGLVKL
                     ALVAQTLGTDPHAFAGADLLERLAPLQEESGRFRDGTADPAAEQTNAFTQALAIIVLKR
                     AGLPTGKAVAYQVSTQCPDGGFPIAFGQATCQSDVDGTAMVLQALLTAGEKTAAPKAVQ
                     WLAAQQKADGGFPSATAGSNSNSTGLAVGALVAGGRAAEADRAVAYLKSVQVGCSGPEA
                     QRGAVAYDATGYQQYPAIRATTQAILGLARVSLADVSAASATAGVPAIDCTTAPPTSSS
                     PSPSPEPTVPAPAGPETPADPPLAATGPEQAVPLSLFGSFAVLAGAALVLVSRRRKGGA
                     "
     regulatory      complement(7124..7232)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            7300..8859
                     /locus_tag="ND450_RS26035"
                     /old_locus_tag="ND450_26035"
     CDS             7300..8859
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039462.4"
                     /locus_tag="ND450_RS26035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_26035"
                     /product="DUF6461 domain-containing protein"
                     /protein_id="WP_253321260.1"
                     /transl_table=11
                     /translation="MGDFEELVRTAAPSVEALIPAEPAAELGRHTVRRSPDRFSGGSVA
                     QQALHLFPGLIAERLLGALELGVARLDLTAPAHVVARLRPLPDGSSFMLLSANGQSAMT
                     TPMSMVNAVHPGAADLVVDQVRALLPDLGDVTGDEAAIAAKRGAAHLAVAVVVSRAVLN
                     ALGTPTAADPAAAIGIAIGAIAEVLPDVPMPAAYEQAVLEKRRAEYRGSSWSTTVPVFD
                     HEFVFAEEAAFPGTDFTATGLVAAIDTGFAVRTGIAEGTVPVSVRVVLDEPGEPDLADW
                     DEVAETSFAARRGDARFGHGGMPPWPGEFRVRVHAHGRDGDDDESHHLLIWPAPHAEPL
                     VHKKTDRVGHRLRGEPEPARAAAPEAALRWLPALLGAAATVTVVTGVADVDGFGPDAIT
                     AEVDGGVVVLELDGFAGTERAVLERLSRNGRAASHFWNGNGDRCLSFARAGRVLVSREP
                     WEHTNFGDDPEVVAALAGLDFDAWRHKEAKGVTAVTRFTGVVLPQDDLTAVIRERVSRW
                     EG"
     gene            complement(8840..9928)
                     /locus_tag="ND450_RS26040"
                     /old_locus_tag="ND450_26040"
     CDS             complement(8840..9928)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009081440.1"
                     /locus_tag="ND450_RS26040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_26040"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_253321261.1"
                     /transl_table=11
                     /translation="MKNVLISGASIGGPALAYWLRHHGFHVTVVERHRGLRPGGQAIDV
                     RGPALEVVERMGLGDRLRSSSTNMRGMNVVDADGTELFRSTTHTVSGGDLSSPDVELLR
                     DDLARMLFDAAEGVEYLFDDTITSIDGTRVTFEKAPPRDFDVVVGADGLHSQVRRLVFG
                     PESRFVSHLGTNLAVFTAPNFLGLDHWQTFQQGDVIGGGIMSARSNTECRVYMGFTGEV
                     DFDHRDVDAQRRLIAEKFEGAGWVWPTAVKHMWEAPDFHMDSMSQIRMDSWSRGTVVLL
                     GDAGYCGSPLSGQGTSMALVGAYVLAGELAKDPSTAFRRYEEILRPYVLANQDMALKNQ
                     ANGGAPTDEFAEVVNSLSLPTY"
     gene            complement(10001..12115)
                     /locus_tag="ND450_RS26045"
                     /old_locus_tag="ND450_26045"
     CDS             complement(10001..12115)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018684951.1"
                     /locus_tag="ND450_RS26045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_26045"
                     /product="germacradienol/geosmin synthase"
                     /protein_id="WP_253321262.1"
                     /sec_met_domain="T1TS (E-value: 7.4e-75, bitscore: 252.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPFQLPEFYTPHPARLNPNLDRARVHSRAWAHEMDMIGTGVWTAE
                     DLESHDYGLLCAYTHPDCDGEALDLVTDWYVWVFYFDDHFVELYKRNPDIEGAQAHLGR
                     LPLFMPLNGVIRETPANPVEKGLADLWRRTVPAHSRDWRERFAANTKHLLDESMWELHN
                     ISSNRLSNPIEYVEMRRKVGGAPWSANLVEHAVGLEMPAGIASSRPVGVLRDTFSDAVH
                     LRNDLFSYEREVLDEGELSNGVLVFEKFLGLPTQQAAEAVNDLLTSRLHQFEHTALTEV
                     PILLDEHAIDPIGRAAVLGYVKGLQDWQAGGHEWHLRSSRYSKQAPKPRPGILGSYAKT
                     MPQRIRQFSSTPKVVEPYVLPEFTTPFALTLSPHVDQARDECVAWAVEHGMTSEGVWDA
                     GKVRGFDFPLCSAGIDPDATPEELFLSGCWLTWGTYADDVYPLWFGQTRNLLGLKTQTA
                     RLKACMPLDLVQTLLPANAMELSLADLWGRTAAPMTPAFRATFRDTIDAMLDAWVWEVV
                     NMHHNRIPDPIDYVEMRRSTFGSELTTSLSRFSHSATVPPELWETRVLQTMERSAMDYC
                     TMLNDVFSYRKEIQHEGEVHNMVRVVENFLGVPQKRAFEITYALMDARLGQFVESVETD
                     LPKLFEDLALDAGARAGLTRYADELKDWIAGIVHWHEETSRYTETAEVPSFQQGPSGLG
                     TSAYRIAVRR"
     gene            complement(12260..12874)
                     /locus_tag="ND450_RS26050"
                     /old_locus_tag="ND450_26050"
     CDS             complement(12260..12874)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098743.1"
                     /locus_tag="ND450_RS26050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_26050"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_371927413.1"
                     /transl_table=11
                     /translation="MSNGIAGIRPADGGLDQGVERTMGGVPTFPHGRPLTWADLEAMPD
                     DGHRFELVDGVLVMSPSPRPVHQRVVARLLVALTAACPPELEVLPAPVDVVLADDTVFI
                     PDLVVGRREQFSKQALIGPPVLAVEVLSPRTRHVDLELKRAKFQEVGCENYWMIDYDAP
                     WLRCLHLENGVYVEQARSDGEEIIELQFPFPVKLSAQSLVR"
     misc_feature    12885..12901
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.37"
                     /tool="antismash"
     misc_feature    complement(13036..13052)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.63"
                     /tool="antismash"
     misc_feature    13040..13049
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.48"
                     /tool="antismash"
     misc_feature    13041..13054
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.8"
                     /tool="antismash"
     misc_feature    13041..13055
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.1"
                     /tool="antismash"
     misc_feature    complement(13042..13055)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.93"
                     /tool="antismash"
     misc_feature    13042..13056
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.72"
                     /tool="antismash"
     misc_feature    complement(13052..13066)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.89"
                     /tool="antismash"
     misc_feature    complement(13101..13119)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.7"
                     /tool="antismash"
     gene            complement(13356..16271)
                     /locus_tag="ND450_RS26055"
                     /old_locus_tag="ND450_26055"
     CDS             complement(13356..16271)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="ND450_RS26055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_26055"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_253321263.1"
                     /transl_table=11
                     /translation="MDVRSFGLLGPLEVVLDGRRVHVPPGKRRVVLAALLLRPGQVVPV
                     DELVELAGGSRNALQTAVGRLREVLPSLVLSRPGGYLLDVRPDEVDVHRFDHLEPREAL
                     ALWRGRPFADIGSDALERDHVPALTEKYLTALEARIEADLARGGHEQLVPELRSLTRQH
                     PVRERLWAQLVVALHRCDRQTEALQAYDDIRGRLADELGLDPGRDLQRAHQQVLTADNR
                     PRARNDLPGDIADFAGRTEDLDEILAAVPSGCVAITAIDGMAGIGKTTIAVRAAHRLAG
                     RFPDAQLFVDLHSYTAGVEPRTPSDALMALLTALGVPAQSIPDGLDARAARWRAEMAHR
                     KALVVLDNAGSAAQVRPLLPGTGLVLVTSRRRLVDLDAAHTISLDVLSEEDSLKLLASI
                     ARRTGEDCREVVRLCGYLPLAVRIVGARWRTRPAWSAQDLVRRLSEQRLVELTAGERSV
                     AGAFALSYQQLTAEQQRLFRLLGLHTGEDWDAHLAAAVIGTTRAEAERLLDELLDAHLV
                     QQKENGRYRFHDLLADQAKACVEPEERGETITRILDFYLRGAEDSARKIAPGRPKFASA
                     ITHDPVDPPVFATPVQALAWQEAERRNLKVAVYLAAYEGHYQHAWQLPSNFAHYLWLHG
                     SGRERVEVQSVALAAAHALGDLKARAEALRGLGAAYMDDGNPKAEEHLREALALMRQIG
                     DLRGEASTLGFLGMIARERRDYDTSMEHFQRGLELMREAGAPSGIAVALHNIGINHAEL
                     GQNEQALAHMWEAAALVQARGDVREFGVTLNNIAHAHFDAYQDEECLDCMERSLACYRE
                     CGDRRGEALALSDFARWRYEMGHLAAAGAMARDVARLCREYMNLPDDEAVLAAMKEVRD
                     HVGQMTLLMSLSLDALTGGRPAESIRYLRRFQELERVRRWWSDERVFQQFAAAHLELGE
                     REAAVRYAERAVEAAERGHQPRILAVARDTLAKAQSPAPPP"
     gene            complement(16262..16852)
                     /locus_tag="ND450_RS26060"
                     /old_locus_tag="ND450_26060"
     CDS             complement(16262..16852)
                     /EC_number="1.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005166896.1"
                     /locus_tag="ND450_RS26060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_26060"
                     /product="nitroreductase family protein"
                     /protein_id="WP_253321264.1"
                     /sec_met_domain="PF00881 (E-value: 2.4e-18, bitscore: 65.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFQDVVRRRRMVRKFTDEPVSDESIQRIMRNAVRGPSAGFSQGQ
                     GFLVLQGEQLQRLREMFEWWAGEDPKTAPVVVIPFSAKSVYLERYSQEDKAWTSLGDEE
                     RWPVPYWDVDTGMAALLILQTAVDEGLGAVFFGTDKETWPELRAAFGVPDAYVPIGMIA
                     IGHPAEEGISEGASPLRRKRKAFDEVVHWGQWT"
     gene            complement(16893..17420)
                     /locus_tag="ND450_RS26065"
                     /old_locus_tag="ND450_26065"
     CDS             complement(16893..17420)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983798.1"
                     /locus_tag="ND450_RS26065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_26065"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_245786438.1"
                     /transl_table=11
                     /translation="MSGEPDDQVNFGDLMSGFSFDSERIRKRGKKKAQRAPEPPPEPDP
                     YATLPFDEIPPLPSVESGYDSSSIVRAYAWTGGRTTSDVHLEIETLVSVNEFSATAVRP
                     EHQDVLALCAQPRSVAEIAALRGLPLGVTKVLLGDMAGHGLIDVHRTASSYGGDRPDGM
                     LLERVLAGLRRL"
     gene            complement(17417..17815)
                     /locus_tag="ND450_RS26070"
                     /old_locus_tag="ND450_26070"
     CDS             complement(17417..17815)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020501899.1"
                     /locus_tag="ND450_RS26070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_26070"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_253321265.1"
                     /transl_table=11
                     /translation="MSTQVDQFGWLVTNFAERTPGLEHAVVISADGLVLISTSKLPAHV
                     APQFAAIVAGVVSLAESASQCFAGEAVVRTVVQMDKGVMLLSSISDGSVLAVLASSTAD
                     VAQVAYEMTVVVRQVGQLLTPELRAELL"
     gene            complement(17812..19890)
                     /locus_tag="ND450_RS26075"
                     /old_locus_tag="ND450_26075"
     CDS             complement(17812..19890)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019974.5"
                     /locus_tag="ND450_RS26075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_26075"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_253321266.1"
                     /transl_table=11
                     /translation="MFNALVNWRNWRLPVKLAAVLIVPVIIATGVGVLQIMSYIDRADS
                     YAEFQRLVKVRASLVPVIEGVQGERRAIAEGSGAESLTDRSRRTERALEGLRGQIGQTV
                     FSDVMSARVADVTAKIGSLPRLREQAGDVPAALAGYTAVTESMLAVDEVLAGEFSDIAL
                     SRTAMGMHHALHVQEEVMNQQSIVLAGLERGQLTSAEVRALLESNVKLGYIADQFAALA
                     TPEQMTTYWTSKFNGPDIEAHRKMLAAAMLHPTSDGPGAGTRPTPLPISAADWSGASGA
                     VGKSMDSVVQGMQDDLLSTANRLRDETSDQAGTASVILFATLILAATIGFGVGRYLLRS
                     LNTLRRSALDVAWNKLPEMVATGRGNTKIEPVPVDTTEELGEVARAFDEVHKQAVKSVI
                     EQAAMRANMRNIFVNLSRRSQSLVERQLKLMEELEKYEEDPDQLANLFKLDHLATRMRR
                     NNENLMVLSGGDVARRFHKPIPLTDVLRAAAAEIEQYQRVMVHTAPNAEVVGYVASDLV
                     RLLAELLDNATAFSPPHTQVSISASIEAGGIVQIDVVDNGIGIDPEALAAVNQRLEAAG
                     EGVDVQVFREMGLFVVGRLAASHQIVVRLDAKQGKGTRAIVLVPAELAPRREESWESFR
                     GEAIERQQTSWFQQTTPAAAPPPPPAPARQTPEAARGFLNAFQRGVQRGLPENQESR"
     gene            complement(19890..20015)
                     /locus_tag="ND450_RS45755"
     CDS             complement(19890..20015)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009950189.1"
                     /locus_tag="ND450_RS45755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_256557306.1"
                     /transl_table=11
                     /translation="MSSPQENRSSTLLLIGAWLWVGLPLAYGLYRLFLNAAKLFV"
     gene            complement(<20138..21454)
                     /locus_tag="ND450_RS26080"
                     /old_locus_tag="ND450_26080"
                     /pseudo=""
     CDS             complement(<20138..21454)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1137: Major
                     facilitator superfamily MFS 1"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020666321.1"
                     /locus_tag="ND450_RS26080"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_26080"
                     /product="OFA family MFS transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGFLARERQVAPPGWNRWLVPPAALAIHLSIGQAYAWSVFKTPLE
                     KSLGITGTQSALPFQLGIVMLGLSAAVLGTTVERRGPRWAMLMSTIAFCSGLLISALGV
                     WAGQYWVVVLGYGLVGGIGLGIGYISPVSTLIKWFPDRPGMATGIAIMGFGGGALIASP
                     WSTSMLTAFGSTTTGIGQAFLVHGIAYAVFMSLGVLLIRLPSKEFTAEKEALLKDRPKA
                     TVAFNVSANNAIKTPQFWLLWVVLCFNVTAGIGILEKAAPMLVDFFKESSTPVAATAAT
                     GFVALLSAANMAGRFIWSSTSDIVGRKNIYRLYLGVGALLYLVLLTVGSTSTPLFVIAA
                     MVILSFYGAGFATVPAYLRDLFGTYQVGAIHGRLLTAWSVAGVLGPLIVNAIADAGKKA
                     GHTGPDLYATSFYIMISLLVVGFVANELIRPVNPKFHEPA"
     misc_feature    complement(21443..21445)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 cggcgtgctg gagttgtact tcatgtccag gtacgccttg ttcgcgggcg acatgacgac
       61 cttgtggccg cgcgccgccg ctgcctgcac cacggcgttg gacgtcgagg tgccccagta
      121 ctgcgggatg gtggcggtgt cggtcgtggt cttcacgaac tcgtgccagc cgagcgccgt
      181 cttgccgtac ttcttcacga tcggcagcgt ccggtccatg aacgtctggt agtcggcgtc
      241 gggcgtggag tgcgcttcgt cgccgccgat gtggaagtac gggccgggcg tgagcgcggc
      301 gatctcgcgg atcacgtcgt ccacgaactg gtaggtgatc tccttgttca cgcacagcga
      361 ggagtagccg acctcgatgt ccgtgcgcag cggcggggcc tggccgttgc agttgagctc
      421 cgcgtacgac gccagcgcgg cgttggtgtg gccgggcagg tcgatctcgg ggatcaccgt
      481 gatcttgcgc gaggccgcgt actgcacgat ctcgctgtac tgcgccttgg tgtagtaccc
      541 gccggggccg ccgccgacct gcgtgctgcc gccgtacgtc gcgaggcgcg gccagctgtc
      601 gatgacgatc cgccagccct ggtcgtcgct caggtggagg tggaagtagt tgatcttgta
      661 gagcgccagc tggtcgatgt agcgcttgac cgtctgcacg gggtggaagt gacgggcaac
      721 gtcgagcatc gcgccgcgat aggagaagcg cgggtggtcg acgaccaggg cgcccggcac
      781 ggtccacgga ccggcctgcg cggtcgtgct ctccaccttg gtgggcagca gctgccgcag
      841 cgtctgcacg cccgcgaaca ggccttccga ggtgttggcg cgcaggacga cgctgcccgt
      901 cgagacgtcg agctggtagc cctgctgacc gaccgcggcc ggcgcgcccg agagcagcag
      961 cgagatgccg tccgacggcg tgccggacgt gtcggagacc gggaacgcgt agccggtcga
     1021 gggccgcagc acgccggcca ggaaggtgcc cacgtcacgg gcggccggtg cggtgtagat
     1081 cttcgtggcg gccgtcagcg tgtgcgtgac accgctcttg gcctgcaccg acaccgggac
     1141 cggcaccagg ctctgcagtg gctccgcggc ttgcgactgc gcgctcacgg acagcgctgc
     1201 ggtgacagcg acgaccgcgg ccagaacgcg agttctcacg actcctcctc acgagtcggg
     1261 ggcggcgacc ctgcctccag cgtgctcaag catccctttt gtcgtcaatg gtctgggcca
     1321 attctttgtt cgggaccggc tcgaaagcag ccttccgggc cgcccggcgc agcgtccgga
     1381 gcagcacggg cgccgtcacc gcgacgagaa cggcggtcgt gacggcccgc atcaggtccc
     1441 agccgagcga ggtggccagc gtgaacgcgg ccagccgcac gaggttcgtg cccggtgagg
     1501 agttcgggtc gaagctgacg gacgtgccct cgccgaccgc gaacggccag aacgacaggt
     1561 tgagcaggaa cccgtagacg agcgagctca cgacgccgta gctcgcgagc agcgcgatct
     1621 cggcccggcc gcgccactgc ggcagcagcc cggcgcccag ggcgacccag gccgcgccga
     1681 gcatctggaa cggcaaccac ggcccgaccc cgccggtcag cagggccgag gcgaacaacg
     1741 tggtgttgcc cagcacgaac ccgaagcccg gcccgaacac gcggccgccg agcaccatca
     1801 ggaagaagac ggtctcgatg ccggcggtgc ccggaccgag cgggcggatc gcggcgccga
     1861 gcgcggacag cacgccgagc atcgcgatcg ccttggagtc catgcccttg tcgctgagct
     1921 cggcgagcac gaccgcgagc accagtggca ggaggagtgc gaacgtccag ggcgcgtcgc
     1981 cgccccgggc gatgtcactc gacggtgcga tgaccagcgg ccaggtgaac gcggccagcc
     2041 cgatcacccc ggagagcgtc agcgcgaccg ccgagcgcct cctgatcgcg atcacagtgc
     2101 cgcctcgacg tccgcgaccg tcagccacgg tccgaggacc ttgctgacct gcggggcgaa
     2161 gatcggcgac gacgtgacga cctcgcgcgc cggaccgtcc gcgacgacct cgccctcggc
     2221 catcacgacg acgcgggtgg cgtactcggc gacgaactcg acgtcgtgcg tggccaggac
     2281 cgtcgtggtg gggaggtcgt ggaggacctt cgccagcgcc tccttggccg ggtggtcgag
     2341 gccgcgcgtg ggttcgtcga gcagcaggac gtcgggtgtg ccggtcagca tcaccgcgag
     2401 caccagcgcg agcttctggc cttcggacag gtcgcgcggg tgggcctgcg gttccaggga
     2461 gaccaggccg tcgaggagtg cgcggcacgt tccggcgggt ctgcccgtct cggtgtcggc
     2521 ctgggcgcac tcctccgcga ccgtttcgag gtagagcagg tcggagggtt gctggggcac
     2581 gagcgcgacg gttcggcgtc gttcggcggg cttcagcgcc ttcgggtcgg tgccgccgac
     2641 cgcgacggtg ccggacgtgc gcttgccgct gccctgcacc gcccacagca gcgacgactt
     2701 gccggaaccg ttgcgtccca tgagcgcgat ccgctcgccc ttgcccgcgg tgagcgagac
     2761 tccgcgcacg gcctggactt ctccgtaccg gacgacgaca tcgcgtgctt cgaggacggg
     2821 ttccgccttc cggacgggct cggtcgcggg ttcgggcagg cgggcgcgca gggaggcggc
     2881 ctggcggcgg gcgtcgcgga ccgagaccgg caccggggtc cagcccgcga gccgggcgag
     2941 ccggacgacc ggtggcgcga ccggtgacct ggtgaggacc tcgccgacct cgccgagttc
     3001 tccctgcggc aacaggagag cgcggtcggc gtactgcgcc acgcgttcga ggcggtgctc
     3061 ggcgatcacg acggtcatgc cgaggtcgtg cacgagccgt tgcacggcgg cgagaacgtc
     3121 ctcggcggcg ccggggtcga gggcggaggt gggttcgtcg aggacgagga ccctcggatg
     3181 cgcggtgagg gcggcgccga tcgcgacccg ttgctgctgg ccgccgctga gtgtcgcgag
     3241 tggacggtcg cggagcgcgg ccaggccgag caggtccagg gtctcctcga cgcgcttgcg
     3301 catgacgtcg ttcggcaggc cgagcgactc catcgagtag gcgagctcgt cctcgacgtt
     3361 gtccgcgacg aagccggcca gcgggtcctg gccgacgaat ccgacgacgt cggccagttc
     3421 gcggggcggg tgcgtggcgg tgtcgcggcc gtcgaccagc acgcgcccgg cgagcgtgcc
     3481 gccgctgaag tgcgggacca ggccgttgat cgcgcgcagg aaggtcgact tgccggagcc
     3541 ggtgcggccg acgaccaggc agagctcgcc ctcgggaatc tccagggaga ggtgcgcgag
     3601 cacgggccgc tcggcgtagg tgatggtgac gtcctcgaac ctgatcatcg ttccctcacg
     3661 agtcccaccg gtgccagggc cagcagcacc ccgatcgccg gaaccagcgg cagttccggc
     3721 gcctgcaacg gcaccgtcga cggcgacaac gccggatcgg ccgagaacac cagcaccacc
     3781 gccccggcca ccccgctcac cgccaccgcg atcgccgtgg gcgtccaccg gtccggccgg
     3841 taccgcgtgc gcggcacccg gcgcgccccg accttgagcc ccgcgaccgc cagcactcct
     3901 ccgaccgcga gcaacggcca gccggtgtac gcaccggcga gcaacccgta ggtgccgatg
     3961 cagatcccgg ccaacccggc cagcaccaac gccccggtcc acgcccggtc ccggcgcgag
     4021 atcccggccg tgcgcccgta cccccgcgag tccatcgagg cggccagcac cagcgaccgg
     4081 tcgagcgcgt cctccagcac cggcaccagc atcgtgcgga tcgcgcgcgg ccccttcgcc
     4141 gtgtcgccgc gcaactgcct cgccctgcgc accgaccgcg cggacgcgac cagctgcggc
     4201 gccacggtca gcgcgaccac gacggccacg ctcacctcgt acagcgcggc cgggagcgac
     4261 cggagaaggc gcttggggtt cgcgagggcg ttggcggcgc cgacacaact gaggatcgtc
     4321 gcgagcaaca gaccttggta cagcgcgaaa accatgcctt cggccgtgac cgggccgccg
     4381 acgcggatgc cctgggccca gtcggggagc gggacctgcg gcagggtgaa gagcacggtc
     4441 gggcccgtga cgccgccgag caacgcgtgc acgagcaccc ggagaccgat gaccagcagg
     4501 ccgaacttga ggaagacgcc gtaggtgccg gcccacggtg tggtggcccg gcacgtcacg
     4561 acgaccacgc ccgcgacggc gaggaccagg cccagcagca acgggttcgt ggtgcggctg
     4621 gcggcggtgg cgaggccgag ggcccacagc caccacgcgc cggagtgcag cctcacgccc
     4681 gcgtcacctg aggtcgcgtg actcggggct tcactcgtct tccaccgcac ggcgccgacg
     4741 tgccacgagc aaccccgcca ccaccagtgc cgcgatcacc agcactgcca acagcgtcca
     4801 cacccacccg aggcccggct tctcctccac ctgccgcgac ttctccgcga cagccggagc
     4861 cgacgtctcc cccgccgcca ccgacgacac ctccgctgac gaagccggaa caacggacga
     4921 cggcgccgcg accgaggacg acgacggtgg aggcgccgtg gtcgtctgcg cgggcggttg
     4981 ctgggcaggc ggttgctggg cgggcggctg cggggcagga ggctgccgca ccggcggttg
     5041 cggcggcgcg ggcgcggccg gtggtgcgat gccgggctgt tcgccggcgc cgaacgacca
     5101 cccctgcacg gtgccgcgcg ccgggacgta agtcgccgcg ccctggttgc tgtacgtcca
     5161 cgcgccgcca gccggagcgt gccagtacga ccagtacgcg gtggcgggtg aggcgctgac
     5221 gcacttgtcg gcgtcggtgc ccggcctgcc gttgatgcgg cagacgaaac cggcctgccg
     5281 cgaggcgtag gtgtagccga aacccgccgc cgtcagggcc gcgacaccgg aggacgggct
     5341 gccgggtgcg cagccctgct ggacccctcc gcccaggccg cggtagtcga cgacgacggt
     5401 gacgccgtca cagcccgcgg ccgacgccgg caccggcacg aacgcggcca ccagtgccag
     5461 cgcgacgaag agcctcctca cggagtggcc gccggggcga cgcccgcgcc gaacgcccag
     5521 ccctcgaccg agccgggagc ggggtcgtaa ccgctcgcgc ccgaggtgct gtaggaccag
     5581 gtgccaccgg ggctcgcgtg ccagtacgac cagtacgcgc tggtcgtggg cacggtgcac
     5641 gggttcggga gcgcgttgat gcggcacacg aaaccgggct ggcgcggcac gaacgagtac
     5701 gtgaagccgg cgccggtcag agcggtgagg cccgtggcgg ggtcaccggc ggcgcacccg
     5761 gtctggacgc ctccgcccag cgaaccgaag tccacgacga cctcgacacc cgcgcacgag
     5821 gccgcggagg ccggtgaggt ggcggcgaac gaccccgcga ccagcgcgag gacagcgagc
     5881 agacggcgca tcacgcacca cccttccggc gacgggagac gaggacgagg gcggcaccgg
     5941 cgagcaccgc gaaggaaccg aacaggctca gcggcacggc ctgctccggt ccggtggcgg
     6001 cgagcggagg gtcggccggg gtctcggggc cggccggagc gggcaccgtc ggttcgggcg
     6061 acggagacgg cgacgacgag gtcggaggcg cggtggtgca gtcgatcgcg ggcacaccgg
     6121 ccgtggcgga cgccgcggac acgtcggcga ggctcacgcg ggccaagccc aggatcgcct
     6181 gcgtggtggc gcggatcgcc gggtactgct ggtagcccgt ggcgtcgtag gcgaccgccc
     6241 cgcgctgcgc ttccggtccg gaacacccga cctgcaccga cttcaggtaa gcgacggccc
     6301 tgtccgcctc ggcggcacga ccgcccgcga cgagcgcgcc gaccgcgaga cccgtgctgt
     6361 tcgagttcga cccggccgtc gccgacggga acccgccgtc cgccttctgc tgcgccgcga
     6421 gccactgcac ggccttggga gcagcggtct tctcccccgc tgtcagcaac gcctgcaaca
     6481 ccatggccgt tccgtctaca tcggactgac aggtcgcctg cccgaacgcg atcgggaagc
     6541 ctccgtccgg gcactgcgtg gacacctggt acgccaccgc cttcccggtc ggcagcccgg
     6601 cgcgcttcag cacgatgatc gccagcgcct gcgtgaacgc gttggtctgc tccgcggcgg
     6661 gatcggcggt gccgtcgcgg aaccgccccg actcctcctg caacggcgcg agccgctcca
     6721 gcaggtcggc tccggcgaac gcgtgcgggt cggtgccgag cgtctgcgcg accagcgcga
     6781 gcttcaccag gccaccgacg tacgactcgg tctcaccgtc cccgatcagg aacgacagct
     6841 ggtccggctg ggcgagccaa gcagcggcct tgaccgccgt cgacttgccg acccccgcgg
     6901 ccgccagcgc gtagacgccg tccgcggtca gcccgggatc gacgatgccg ggaccttgca
     6961 gcaggtggtc cccgtcggcg aactgggcgg cgagccacgt ccccgccgac ggcggttcgg
     7021 ccgcctgtgc ctgcggtgtc accacgagcg ctgtcgccat cacggcgacc aacgcggatc
     7081 tcctgatcac tgcgcctccc tgccccgctg tcctcgacgg gtcgatggag ctaccgcgcg
     7141 ccacgggcaa tcggactatc accgttgcgg gtcagtgccg gagttgcacc ggcttccccc
     7201 gcggcgtgcg gatgctgttg tcaacccagg atcgtgcggg agggatcgat tcgagtcaaa
     7261 tggctgtgag ctgggccatc caccggcaga atcggcggca tgggggattt cgaagagctg
     7321 gtccgcaccg ccgcgccctc ggtcgaggcg ctgatcccgg ctgaaccggc ggccgaactg
     7381 ggccggcaca ccgtgcgcag gagcccggac cgcttctccg gcggatcggt cgcgcagcag
     7441 gcgctgcacc tgtttcccgg gctgatcgcg gaacggctgc tgggcgcgct ggaactgggt
     7501 gtcgcccggc tggacctgac cgcgcccgcc cacgtcgtcg cgcgcctgcg gccgctgccg
     7561 gacggcagca gcttcatgtt gctgtcggcg aacgggcaga gcgcgatgac gacaccgatg
     7621 agcatggtga acgcggtgca ccccggcgcc gcagacctcg tcgtcgacca ggtgcgcgca
     7681 ctgctcccgg acctcggcga cgtcacgggc gacgaggcgg ccatcgccgc gaaacgcggc
     7741 gccgcgcacc tcgcggtggc ggtggtcgtg tcgagggccg tgctgaacgc gctgggcacg
     7801 ccgaccgcgg cggatccggc cgccgccatc gggatcgcga tcggcgcgat cgccgaggtc
     7861 ctgccggacg tcccgatgcc ggccgcgtac gagcaggcgg tgctggagaa gcggcgcgcc
     7921 gagtacaggg gctcctcctg gagcacgacc gtcccggtgt tcgaccacga gttcgtgttc
     7981 gcggaggagg cggccttccc cggcacggac ttcacggcga ccgggctcgt cgccgcgatc
     8041 gacaccgggt tcgccgtgcg caccgggatc gcggagggca ccgttccggt gtcggtgcgg
     8101 gtggtgctcg acgagccggg agagccggac ctcgccgact gggacgaggt ggccgagacg
     8161 agcttcgccg ctcgcagggg cgacgctcgg ttcgggcacg gcgggatgcc gccctggccg
     8221 ggcgagttcc gcgtccgtgt tcacgcgcac ggccgcgacg gggacgacga cgagagccac
     8281 cacctgttga tctggcccgc gccgcacgcg gaaccgctgg tgcacaagaa gaccgaccgg
     8341 gtcggccacc gcctgcgcgg ggaaccggag cccgcccgcg cggcagctcc ggaggccgcg
     8401 ctgaggtggc tgccggccct gctcggtgcg gcggcgaccg tcacggtggt caccggtgtg
     8461 gccgacgtcg acggcttcgg gccggacgcg atcaccgccg aggtcgacgg cggcgtggtc
     8521 gtgctggagc tcgacggctt cgccggtacc gaacgcgcgg tgctggaacg cctgtcccgc
     8581 aacgggaggg ccgccagcca cttctggaac ggcaacggcg acaggtgcct gtcgttcgcg
     8641 agggccggtc gcgtcctcgt ctcccgggaa ccctgggagc acacgaactt cggcgacgac
     8701 ccggaggtcg tcgccgccct cgccggactc gacttcgatg cgtggcggca caaggaggcc
     8761 aagggtgtca cggcggtgac ccgcttcacc ggcgtcgtgc tcccccagga cgacctcacc
     8821 gccgtgatcc gcgagagggt cagtaggtgg gaaggctgag gctgttcacg acctcggcga
     8881 actcgtcggt gggcgcgccc ccgttggcct ggttcttcag cgccatgtcc tggttcgcga
     8941 gcacgtaagg gcgcaggatc tcctcgtagc gccggaaagc cgtcgagggg tccttcgcca
     9001 gctctccggc aagcacgtac gcgccgacca gcgccatgct ggtgccctgc ccggacaacg
     9061 gcgagccgca gtagccggcg tcgccgagca gcacgacggt gccgcgggac caggagtcca
     9121 tccggatctg gctcatcgag tccatgtgga agtccggtgc ctcccacatg tgcttcacgg
     9181 cggtcggcca cacccagccg gcgccctcga acttctcggc gatcaaccgg cgctgcgcgt
     9241 ccacgtcgcg gtggtcgaag tcgacctcgc ccgtgaaacc catgtagacg cggcactccg
     9301 tgttcgaccg ggcgctcatg atcccgccgc cgatgacgtc gccctgctgg aacgtctgcc
     9361 agtggtcgag gccgaggaag ttcggcgcgg tgaagacggc gaggttcgtg ccgaggtgcg
     9421 agacgaaccg cgactcgggc ccgaacacga gcctgcggac ctgggagtgc aggccgtccg
     9481 cgccgacgac cacgtcgaag tcgcgcggtg gcgccttctc gaacgtgacg cgggtgccgt
     9541 cgatcgaggt gatggtgtcg tcgaagaggt actcgacgcc ctcggccgcg tcgaacagca
     9601 tgcgggcgag gtcgtcgcgc agcagttcga cgtcggggct cgacaggtcg ccgccgctca
     9661 cggtgtgggt ggtggagcgg aagagttcgg tgccgtcggc gtcgaccacg ttcatgccgc
     9721 gcatgttcgt gctggacgac cgcagccggt cgccgagacc cattcgctcg acgacctcca
     9781 gcgcgggtcc gcggacgtcg atggcctggc cgccgggtcg cagaccgcgg tggcgctcga
     9841 ccaccgtgac gtggaagccg tggtggcgca gccagtacgc gagggcgggg ccgccgatgc
     9901 tggcgccgga gatcaggacg ttcttcacgg tgttccccct gtgggtcggt ggtgcccaca
     9961 aggtgccgac cggcgctgac caccggctga ccggacgcgg tcagcgccgg acagcgatcc
    10021 ggtacgccga ggtgccgagg ccggagggcc cctgctggaa cgaggggacc tccgcggttt
    10081 cggtgtagcg gctggtctcc tcgtgccagt gcacgatgcc ggcgatccag tccttcagct
    10141 cgtcggcgta ccgggtcagg ccggcgcgcg ccccggcatc gagtgccagg tcctcgaaga
    10201 gcttcggcag atcggtctcg accgactcga cgaactggcc gaggcgggcg tccatcaacg
    10261 cgtaagtgat ctcgaaggcg cgtttctggg gcacgccgag gaagttctcg acgacgcgca
    10321 ccatgttgtg cacctcgccc tcgtgctgga tctccttgcg gtacgagaag acgtcgttga
    10381 gcatcgtgca gtagtccatg gccgaacgct ccatcgtctg caagacccgc gtttcccaca
    10441 gctccggcgg gacggtggcg gagtgcgaga agcgcgagag cgacgtcgtc agctcggagc
    10501 cgaacgtgct gcgccgcatc tccacgtagt cgatcgggtc ggggatgcgg ttgtggtgca
    10561 tgttgaccac ctcccacacc cacgcgtcga gcatcgcgtc gatcgtgtcc cggaacgtcg
    10621 cccggaacgc gggcgtcatg ggtgccgcgg tgcgccccca caggtcggcc agcgagagct
    10681 ccatggcgtt ggcggggagc agggtctgca cgaggtcgag cggcatgcac gccttgagcc
    10741 gggccgtctg cgtcttcagg ccgagcaggt tgcgggtctg gccgaaccac aacgggtaga
    10801 cgtcgtcggc gtaggtgccc caggtgagcc agcagccgga caggaacagc tcttccggcg
    10861 tcgcgtccgg gtcgatgccg gccgagcaca gcgggaagtc gaacccgcgc accttccccg
    10921 cgtcccagac gccctcgctc gtcatgccgt gctcgacggc ccacgcgacg cactcgtccc
    10981 tggcctggtc gacgtgcggg ctcagggtca gcgcgaacgg cgtcgtgaac tccggcagca
    11041 cgtacggctc gacgaccttc ggcgtgctgg agaactgccg gatccgttgc ggcatcgtct
    11101 tggcgtacga gccgaggatc cccggtcgcg gcttcggggc ctgcttgctg taccgcgacg
    11161 accgcaggtg ccactcgtgc ccgcccgcct gccagtcctg caggcccttc acgtagccca
    11221 ggacggccgc gcgcccgatg gggtcgatcg cgtgctcgtc cagcaggatc ggcacctcgg
    11281 tgagcgccgt gtgctcgaac tggtgcagcc gcgaggtcag caggtcgttg acggcctcgg
    11341 cggcctgctg ggtcgggagg ccaaggaact tctcgaacac cagcacgccg ttggacagct
    11401 cgccctcgtc gagcacctcg cgttcgtagg agaacaggtc gttgcgcagg tgcacggcgt
    11461 cgctgaaggt gtccctgagc accccgacgg gcctgctgga cgcgatgccc gccggcatct
    11521 ccaggccgac ggcgtgctcg acgaggttcg cgctccacgg cgcgcccccg accttgcggc
    11581 gcatctcgac gtactcgatg gggttggaca gcctgttgga gctgatgttg tgcagctccc
    11641 acatcgactc gtccagcagg tgcttcgtgt tggcggcgaa ccgttcgcgc cagtcgcgtg
    11701 aatgcgccgg gacggtgcgg cgccagaggt cggcgagacc tttctcgacc gggttggcgg
    11761 gggtttccct gatgacgccg ttgaggggca tgaagagcgg gaggcggccg aggtgggcct
    11821 gcgcgccctc gatgtccggg ttccgcttgt acagctcgac gaagtggtcg tcgaagtaga
    11881 agacccacac gtaccagtcg gtgacgaggt cgagcgcctc accgtcgcag tcggggtggg
    11941 tgtaggcgca gagcaacccg tagtcgtgcg actccaggtc ctcggcggtc cagaccccgg
    12001 tgccgatcat gtccatctcg tgcgcccagg cgcggctgtg gacgcgggcg cggtcgaggt
    12061 tcgggttcag ccgggccggg tggggcgtgt agaactccgg cagctggaac ggcatgtgcg
    12121 ttggacctcc gcgcgtcggg ctggacgcac tgcacgcaac cagcccggca cgcgcgaacg
    12181 ccagatggtg gcaccgtgat ccacacgagc gtggcgtggt gtcgcccgtt cagcccagcg
    12241 aggtcgcgga gggcgatact cagcgcacca gcgactgggc gctgagcttc accgggaacg
    12301 ggaattgcag ctcgatgatc tcctcgccgt cggaacgggc ctgttcgacg tagacgccgt
    12361 tttccaggtg caggcaccgc aaccacgggg cgtcgtaatc gatcatccag tagttctcgc
    12421 aaccgacttc ctggaacttc gcccgcttga gttcgaggtc cacgtgccgc gtgcgcggcg
    12481 aaaggacctc gaccgccagc accggcggtc cgatgagcgc ctgtttcgag aactgctccc
    12541 gccgccccac gaccaggtcg gggatgaaca ccgtgtcgtc ggcgagcacg acgtcgaccg
    12601 gagccgggag gacctcgagc tccggtgggc aggcagcggt cagcgccacc agcaggcggg
    12661 cgaccacgcg ctggtgcacg gggcggggtg aggggctcat gaccagcacc ccgtcgacga
    12721 gttcgaaacg gtgcccgtca tcaggcatcg cctccaggtc cgcccacgtc agcggtctgc
    12781 cgtggggaaa cgtcgggaca ccacccatgg tgcgttccac cccctggtcg aggccaccgt
    12841 ccgccggacg gatcccggcg atgccattag acaagactgg tccggttcgc acgactcgca
    12901 agcccctttt ggccgacccc acaccactgc acgcacacca ctccgtcaac accgtcccgc
    12961 agggtgagcg gtgactggtc ctgccgtgga cggcaccacc cggacggagc agcgagatgg
    13021 tttcaatcga acaagtggct aatttttgat caattttcgg gcgattttcg gtaacgcacc
    13081 ccgccccgcc aattgtccgc gaatgcgacc ctaacggaat cttacgagcg cgccaagcac
    13141 tccgttggag caatacctca cgagtacctc acactgcggt gatcaaaaca cgtcccgacg
    13201 cattccgatg aatccgtgtg atcgcggtgg ggacggcgtg gggacgggct cgcacaccct
    13261 cggtggcatc accaccgagg ggagccaggg gatgcgcagg acgtcggaca ggatcggtca
    13321 gtgggtggcc ttcgccttgg tggcggcggc cgtgatcacg gtggtggcgc tggggattgc
    13381 gctttagcga gcgtgtccct ggcgacggcg aggatccggg gctggtggcc gcgctctgcg
    13441 gcctccaccg cccgctccgc gtaccggacg gccgcctccc gctcacccag ttccaggtgc
    13501 gcagccgcga actgctggaa cacgcgttca tcgctccacc agcggcgcac cctctcgagc
    13561 tcctggaacc gcctcaggta gcggatcgac tcggcaggac ggccacccgt cagggcgtcg
    13621 agcgacaacg acatcaacag cgtcatctgc ccgacgtggt cgcgaacctc cttcatcgca
    13681 gccagcacgg cttcgtcgtc gggcaggttc atgtactccc ggcacagcct cgcgacgtcg
    13741 cgcgccatcg cgcccgcggc ggcgaggtgg cccatttcgt agcgccatcg ggcgaagtcg
    13801 gacagggcga gcgcttcacc ccgccggtca ccgcactccc ggtagcacgc gagcgaccgt
    13861 tccatgcagt cgaggcattc ctcgtcctgg taggcgtcga agtgcgcgtg ggcgatgttg
    13921 ttcagcgtca ccccgaactc gcggacgtca ccgcgcgcct gcaccagcgc ggccgcttcc
    13981 cacatgtgcg cgagggcttg ctcgttctgc cccagctccg cgtggttgat gccgatgttg
    14041 tgcaacgcga cggcgatccc gctgggcgcg ccggcttcgc gcatgagctc gagaccgcgt
    14101 tggaagtgct ccatcgacgt gtcgtagtcg cgccgttcgc gcgcgatcat gccgaggaaa
    14161 cccagcgtgg aggcctcgcc tcgcagatca ccgatctgcc gcatgagggc gagtgcttcc
    14221 cgcaggtgtt cctcggcctt cgggttgccg tcgtccatgt acgccgcccc caggccgcgc
    14281 aacgcttccg cgcgggcctt caggtcaccg agcgcgtgcg cggccgcgag cgcgacgctc
    14341 tgcacctcga ctcgttccct gcccgatccg tgcaaccaca ggtagtgcgc gaagttgctc
    14401 ggcaactgcc aggcgtgctg gtaatgccct tcgtacgcgg ccaggtacac ggcgaccttg
    14461 aggttgcgcc gttccgcctc ctgccacgcc aacgcctgca ccggtgtggc gaacaccggt
    14521 ggatcgacgg ggtcgtgggt gatcgcggac gcgaacttcg ggcggccggg ggcgattttg
    14581 cgggcggagt cctccgcgcc gcgcaggtag aagtcgagga tccgggtgat cgtctcgcct
    14641 ctctcctccg gctcgacgca cgccttcgcc tggtccgcca gcaggtcgtg gaaccggtag
    14701 cgcccgttct ccttctgctg caccaggtgc gcgtcgagca gctcgtccag cagccgttcg
    14761 gcctcggcgc gggtcgtgcc gatcaccgcc gccgccaggt gggcgtccca gtcctccccc
    14821 gtgtgcagtc ccagcaaccg gaacagccgc tgctgctcgg cggtgagttg ctggtaggac
    14881 aacgcgaacg cgcccgcgac gctgcgttcg cccgcggtca gttcgacgag gcgctgctcg
    14941 ctcaggcggc ggaccaggtc ctgcgcggac cacgccggcc tggtgcgcca gcgggcgccg
    15001 acgatccgca cggcgagcgg gaggtagccg cagagccgca cgacctcccg gcagtcctcg
    15061 ccggtcctgc gggcgatgct cgccagcagc ttcagcgagt cctcttcgga cagcacgtcc
    15121 agcgagatgg tgtgggcggc gtccaggtcc accaggcggc gcctgctggt gacgagcacg
    15181 agaccggtgc ccggcaggag tgggcggacc tgggcggcgc tgcccgcgtt gtcgaggacc
    15241 acgagtgcct tgcggtgcgc catttccgcg cgccaccggg cggcgcgggc gtccaggccg
    15301 tccgggatgc tctgcgcggg cacgccgagg gccgtgagca acgccatcag ggcgtccgac
    15361 ggggtgcgcg gctcgacgcc cgccgtgtac gagtgcaggt ccacgaagag ctgtgcgtcg
    15421 gggaaacggc ctgccaggcg gtgggcggcg cggacggcga tggtcgtctt gccgatgccc
    15481 gccatgccgt cgatcgcggt gatcgcgacg cacccggacg gcacggcggc gaggatctcg
    15541 tccaggtcct cggtgcggcc cgcgaagtcg gcgatgtcgc ccgggaggtc gttgcgggcg
    15601 cgcggtctgt tgtcggccgt gagcacctgc tggtgggctc gttgcaggtc ccggccgggg
    15661 tccaggccga gttcgtcggc gaggcggccg cggatgtcgt cgtacgcctg caacgcctcg
    15721 gtctgccggt cgcagcggtg cagcgccacg accagctggg cccacagccg ttcccggacg
    15781 gggtgctgac gggtgagcga ccgcagttcg ggcaccagct gttcgtggcc gccgcgcgcg
    15841 aggtcggcct cgatccgggc ttccagcgcc gtcaggtact tctcggtcag cgcgggcacg
    15901 tggtcgcgtt ccagggcgtc gctgccgatg tcggcgaacg ggcgcccgcg ccacaacgcg
    15961 agtgcctcac ggggttccag gtggtcgaac cggtggacgt cgacctcgtc gggccgcacg
    16021 tccagcaggt atccgccggg cctggagagc accagcgagg gcagcacctc gcgcaggcgg
    16081 ccgaccgcgg tctgcaacgc gttgcgcgaa ccaccggcca gttcgaccag ctcgtcgacc
    16141 ggaacgacct gacccggccg cagcagcaac gcggcgagca ccacgcgccg cttgcccggc
    16201 gggacgtgga cccggcgccc gtcgagcacc acctccagcg gcccgagcag gccgaacgac
    16261 ctcacgtcca ctgaccccag tgcacgacct cgtcgaacgc cttgcgcttg cgccgcagcg
    16321 gcgaggcgcc ctcggagatg ccctcctccg ccgggtgccc gatcgcgatc atgccgatcg
    16381 gcacgtacgc gtccggcacg ccgaaggccg cacgcagctc cggccaggtc tccttgtccg
    16441 tgccgaagaa gacggcaccc agaccctcgt cgacggccgt ctgcaggatc agcagcgcgg
    16501 ccatgccggt gtcgacgtcc cagtacggca ccggccagcg ctcctcgtcg ccgagcgagg
    16561 tccaggcctt gtcctcctgg gagtagcgct cgaggtagac ggacttggcc gagaacggga
    16621 tgacgacgac gggcgccgtc ttcgggtcct ccccggccca ccactcgaac atctcgcgca
    16681 gccgctgcag ctgctcaccc tgcagcacca ggaacccctg gccctgcgag aaccccgccg
    16741 acggaccgcg cacggcgttg cgcatgatcc gctggatgct ctcgtcgctg accggctcgt
    16801 cggtgaactt gcgcaccatc cgccggcgac ggaccacgtc ctggaactcc acggctaccc
    16861 ccagtcgtct cgactcgacc gtagcgcagg ggtcagagcc ggcgcaggcc cgccagcacg
    16921 cgttcgagca gcatcccgtc cggccggtcg ccgccgtagg acgacgccgt gcggtgcacg
    16981 tcgatcagcc cgtgcccggc catgtcgccg agcagcacct tggtgacgcc cagcggcagc
    17041 ccgcgcaggg cggcgatctc cgccaccgaa cggggctgtg cgcacagcgc cagcacgtcc
    17101 tggtgttccg ggcgcacggc cgtggccgag aactcgttga ccgagaccag ggtctcgatc
    17161 tccaggtgca cgtcggaggt ggtgcggccg ccggtccacg cgtaggcgcg cacgatcgac
    17221 gacgagtcgt agcccgactc gaccgacggc agcggcggga tctcgtcgaa cgggagggtc
    17281 gcgtacgggt ccggctccgg cggcggttcc ggcgcgcgct gggccttctt cttgccgcgc
    17341 ttgcggatcc gctcgctgtc gaagctgaac ccgctcatca ggtcaccgaa gttgacctga
    17401 tcgtccggtt ccccgctcac aggagctcag ccctcagctc gggagtgagc agctggccca
    17461 cctggcggac gacgaccgtc atctcgtagg cgacctgcgc gacgtcggcg gtcgaggacg
    17521 ccagcaccgc gaggaccgag ccgtcgctga tcgaggacag cagcatgacg cccttgtcca
    17581 tctgcacgac cgtgcggacg accgcctcac cggcgaagca ctgcgacgcc gactcggcga
    17641 gcgagaccac tccggccacg atcgccgcga actgcggcgc gacgtgcgcc ggcagcttcg
    17701 acgtcgagat caacaccagg ccgtccgcgg agatcaccac ggcgtgctcg agaccgggcg
    17761 tgcgttcggc gaagttggtg accagccagc cgaactggtc cacctgcgtg ctcatcgact
    17821 ctcctggttt tcgggaaggc cgcgctgcac accgcgctgg aaggcgttga ggaaacctcg
    17881 agcggcttct ggcgtctggc gtgcgggtgc ggggggaggc ggcggtgcgg cggcgggcgt
    17941 cgtctgctgg aaccacgagg tctgctgccg ttcgatcgcc tcccctcgga aagactccca
    18001 ggactcttcc cgccgtggtg ccagttcggc cggaaccaac acgatcgcgc gagtcccctt
    18061 gccttgtttc gcgtccagac gtaccacgat ctggtggctc gcggcgagcc ttccgacgac
    18121 gaagagaccc atctcccgga agacctgcac gtccacgccc tcgcccgcgg cctcgaggcg
    18181 ttggttcacc gcggcgagcg cctcggggtc gatgccgatg ccgttgtcga cgacgtcgat
    18241 ctggacgatg ccgcccgcct cgatcgacgc gctgatcgag acctgggtgt gcggcggcga
    18301 gaacgccgtc gcgttgtcga ggagctcggc gagcaggcgg accaggtcgc tcgccacgta
    18361 gccgacgacc tcggcgttgg gtgccgtgtg caccatgacc cgctggtact gctcgatctc
    18421 cgcggccgcc gcgcgcagca cgtcggtgag cgggatcggc ttgtggaacc gccgggccac
    18481 gtcgccgccg gagagcacca tcaggttctc gttgttgcgg cgcatgcggg tggcgaggtg
    18541 gtcgagcttg aagaggttcg ccagctggtc cgggtcctcc tcgtacttct ccagctcctc
    18601 catcagcttg agctggcgtt cgacgaggct ctggctgcgg cgcgagaggt tcacgaagat
    18661 gttgcgcatg ttcgcgcgca tcgcggcctg ctcgatcacc gacttcacgg cctgcttgtg
    18721 cacctcgtcg aacgcgcgcg ccacctcgcc gagttcctcg gtcgtgtcca cgggcacggg
    18781 ctcgatcttc gtgttgccgc gtccggtggc gaccatctcg gggagcttgt tccacgccac
    18841 gtcgagagcg gacctgcgca gcgtgttcag cgaacgcagc aggtagcggc ccacgccgaa
    18901 gccgatggtg gccgcgagga tcagggtggc gaacaggatg acggacgccg tgccggcctg
    18961 gtcgctggtc tcgtcgcgca gccggttcgc ggtgctgagc aggtcgtcct gcatgccctg
    19021 cacgacgctg tccatcgact tgccgaccgc gccggaggca ccgctccagt ccgccgccga
    19081 gatcggcagc ggggtgggcc tggtgccggc gcccggaccg tcggaggtcg ggtgcagcat
    19141 cgcggcggcg agcatcttgc ggtgcgcctc gatgtccggc ccgttgaact tcgacgtcca
    19201 gtaggtggtc atctgctcgg gcgtcgcgag agcggcgaac tggtcggcga tgtagccgag
    19261 cttgacgttc gactcgagca gcgcgcgcac ctcggcgctg gtcagctggc cgcgttcgag
    19321 cccggccagc acgatcgact gctggttcat cacctcttcc tgcacgtgca gggcgtggtg
    19381 catgcccatc gccgtgcggg agagcgcgat gtcgctgaac tcgccggcga ggacctcgtc
    19441 cacggcgagc atcgactcgg tgacggcggt gtaccccgcg agcgcggccg gcacgtcgcc
    19501 cgcctgctcg cgcaaccgcg gcaggctgcc gatcttcgcc gtcacgtcgg ccaccctggc
    19561 cgacatgacg tcgctgaaca cggtctggcc gatctggccg cgcagtccct ccagcgctcg
    19621 ttcggtgcgg cgcgaccggt cggtgagcga ctcggcgccc gatccctcgg cgatggcccg
    19681 ccgctctccc tgcaccccct cgatcacggg gacgagggag gcgcggacct tcaccagccg
    19741 ctggaactcc gcgtaggagt cggcccggtc gatgtaggac atgatctgca gaacgccgac
    19801 gcccgtcgcg atgatgaccg gaacgatcaa caccgcggcg agcttcaccg gcaggcgcca
    19861 gttgcgccag ttgacgagcg cgttgaacat cagacgaaga gcttggccgc gttcaggaag
    19921 agccggtaca ggccgtaggc gagcggcagg cccacccaca gccacgctcc gatcagcaac
    19981 aacgtgctcg atcggttctc ctggggtgag ctcacttctt caccgcgcct tccgcgtcct
    20041 gcttctcggc cgactcggcg gcgtccgcag cttctgcttc gttccacttg gcgaccgcgt
    20101 cctcgtcctg cgcgggcgag ggctgcgcgg tcccggccgc gggttcgtgg aacttcgggt
    20161 tgaccgggcg gatcaactcg ttcgcgacga aaccgacgac cagcagcgag atcatgatgt
    20221 agaacgacgt ggcgtacaag tcaggaccgg tgtgtcccgc cttcttgccc gcgtccgcga
    20281 tggcgttgac gatcagcggc ccgaggacgc cggccacgga ccacgccgtg agcaggcggc
    20341 cgtggatcgc gccgacctgg taggtgccga acaggtcccg caggtaggcc gggacggtcg
    20401 cgaagcccgc gccgtagaac gacaggatca ccatcgccgc gatcacgaac agcggggtgc
    20461 tggtcgagcc gacggtcagc agcaccaggt agagcagggc gccgacgccg aggtagaggc
    20521 ggtagatgtt cttgcggccc acgatgtccg aagtggacga ccagatgaag cggcccgcca
    20581 tgttcgcggc ggagagcagc gcgacgaaac cggtggcggc ggtcgcggcg accggcgtcg
    20641 aggactcctt gaagaagtcg accagcatcg gggcggcctt ctccaggatg ccgatgcccg
    20701 cggtgacgtt gaagcacagc acgacccaca gcagccagaa ctgcggcgtc ttgatcgcgt
    20761 tgttggcgga gacgttgaac gcgacggtcg ccttcggcct gtccttgagc agcgcttcct
    20821 tctccgccgt gaactccttg gagggcaggc ggatcagcag gacgccgagg ctcatgaaga
    20881 ccgcgtaggc gatgccgtgc acgaggaagg cctggccgat gcccgtcgtc gtggagccga
    20941 acgccgtcag catcgaggtc gaccacggcg acgcgatcag cgcaccgccg ccgaagccca
    21001 tgatcgcgat gccggtggcc atgcccggcc ggtcggggaa ccacttgatc agggtggaga
    21061 ccggcgagat gtagccgatg ccgaggccga tgccgccgac caggccgtag ccgagcacga
    21121 cgacccagta ctggccggcc cagacgccga gcgccgagat cagcagaccg gagcagaagg
    21181 cgatcgtgga catcagcatg gcccagcgcg ggcccctgcg ctccaccgtc gtgcccagca
    21241 cggcggcgga cagcccgagc atcacgatgc cgagctggaa cgggagtgcg gactgcgttc
    21301 ccgtgatgcc aagcgatttc tccaggggcg tcttgaagac gctccaggcg tacgcctgac
    21361 caatggagag atgaatcgcc agagccgcag gcggaacgag ccagcggttc catccgggag
    21421 gcgcgacttg gcgttcgcgc gctaagaacc ccactttatc cccaaccgtc accaataacg
    21481 tggaccgacc ggatcctagg ccaggtgcac acgtgcgaca acggtcttga ggaagccttc
    21541 aggtgttgca cgtctcgcaa cttccgcgat cagcttggta caacccccgg ttcgaaccat
    21601 ttgagacgaa tgaaaagccc gggatcctgt ccggttgtgg tccgattcgg gttcgcggtt
    21661 ggtccggttt ggcccgattc cgcgcaccac gcgacattga ctgcacacgt gagggcgcta
    21721 cagtaggcgc cgcacaccga ggggcagggc cacatgacca aggcgatgag gtcgcctggc
    21781 gaagcgcacc acgagtaccg ggaaatccgg ggtttcgcgt cgttcgacga ccccgatgct
    21841 ttgtcgtacg tcgattccga cggacgcccg aacttcgcgc tgattcagca gaccgacgaa
    21901 ttccgcgtgt tgcgtcgccg actcacgacg ttcatcttcc cgatgaccgc gcttttcctg
    21961 gcgtcctacc tgaccttcgt actgctgtcc gcgtacgcga aagacttcgt cagcaccaag
    22021 gtgatcggcg tgatcaacct cgggatcctg ctgggcctcg gacagtttgt gacttcgatc
    22081 atcatcacgc tcggttatgc ccgttacgca aagcg
//
