LOCUS       NZ_CP099738            22535 bp    DNA     circular CON 27-AUG-2024
DEFINITION  Lentzea sp. HUAS12 chromosome.
ACCESSION   NZ_CP099738
VERSION     NZ_CP099738.1
KEYWORDS    RefSeq.
SOURCE      Lentzea sp. HUAS12
  ORGANISM  Lentzea sp. HUAS12
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 9676923)
  AUTHORS   Ping,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JUN-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024125735.1-RS_2024_08_27
            Annotation Date                   :: 08/27/2024 06:34:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,161
            CDSs (total)                      :: 9,080
            Genes (coding)                    :: 8,988
            CDSs (with protein)               :: 8,988
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 21 of 92
            Pseudo Genes (incomplete)         :: 77 of 92
            Pseudo Genes (internal stop)      :: 3 of 92
            Pseudo Genes (multiple problems)  :: 8 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:47:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4370801
            Orig. end                         :: 4393336
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP099738.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Ping Mo.
FEATURES             Location/Qualifiers
     region          1..22535
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="21"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22535
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22535
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12535](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12535
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            980..1168
                     /locus_tag="ND450_RS19320"
                     /old_locus_tag="ND450_19320"
     CDS             980..1168
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS19320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_19320"
                     /product="hypothetical protein"
                     /protein_id="WP_253327457.1"
                     /transl_table=11
                     /translation="MTSREEAERLLSSLGDEDLVEIDSNGKIYAVGKSPAAASGKSIAG
                     ISDQRGEYGKAGRWTSG"
     gene            1165..1605
                     /locus_tag="ND450_RS19325"
                     /old_locus_tag="ND450_19325"
     CDS             1165..1605
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS19325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_19325"
                     /product="hypothetical protein"
                     /protein_id="WP_253327458.1"
                     /transl_table=11
                     /translation="MTRSLLVSATPDGRLAAEKKILAAHFPQFTLSTRTDAFAVARGQL
                     ETFTGRKYRVEITADSSYPHSLPEIHPVGWTLRPNPHIIRGGLCVMRANQWASFMSVAF
                     LVAKSALWLNKYEVFLDKGIWPGPEQHEHGPIYKVRKWWHEL"
     gene            1595..2437
                     /locus_tag="ND450_RS19330"
                     /old_locus_tag="ND450_19330"
     CDS             1595..2437
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013094.5"
                     /locus_tag="ND450_RS19330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19330"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_253327459.1"
                     /sec_met_domain="ThiF (E-value: 1.1e-29, bitscore: 102.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSDTSFDTSRIDYLVSGAGLRDRKVVVVGLGSGGAVVLERLGMT
                     GVGRWSLYDPDALDPVNLVKHPARRSDLGRAKTDIARTWLLDRNPACTIERIGGNVVGD
                     EGFPADVAGADLVVCAVDTPEARSFVNEVCVRERTPCVFGSVFRTGMGGEVYAYLPGEA
                     GCHDCKVRFSLEQGRDVENWLDLTDEETRRIYGVGEADFSASGLAADISVVASYHAHYV
                     ISLLAGRGSRYLTVPSFNWLTLSLRRVDGLFNAMYDTSRVLLRPRAECHLRCGGGEGR"
     gene            2473..3567
                     /locus_tag="ND450_RS19335"
                     /old_locus_tag="ND450_19335"
     CDS             2473..3567
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS19335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_19335"
                     /product="hypothetical protein"
                     /protein_id="WP_253327460.1"
                     /transl_table=11
                     /translation="MIVPVQVAERFTKEINDHPHVEVGGKYVGFIRGVARHDTLEERLR
                     AVPGLTFEVVDYIDDGPAAQRTAGFHRGDPDWQTAEFRRLEAARPDIEQLGSWHSHHPN
                     GLRELSSGDVHGYQETVDDLGHNHDYFFVSLGVDLKGFVTARHYLFIRGSKKYVELPMS
                     AFQITDGAPDPAVPRETEPEAPGSPAPPEPREQAGPEAPRTEETPEPAPDPPPREVPRQ
                     ARTQPRAETGEHLSVRGWTDSRPGLDALRAEREQLRSPEFAHVRLSIGQGRLLARGWLD
                     TKAGRVSMSLLYPSAIGGDDGLLKLSTLDVPGIDVTLSGPQTRNLVTARVLIGHFIRYA
                     DVHRPLMRKDPDRQSLLQSIKNWF"
     gene            3585..4256
                     /locus_tag="ND450_RS19340"
                     /old_locus_tag="ND450_19340"
     CDS             3585..4256
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS19340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_19340"
                     /product="hypothetical protein"
                     /protein_id="WP_253327461.1"
                     /transl_table=11
                     /translation="MEHNEPPDFPGSAIGSGMDLLAELSSPWTTARAITAPGLTRQLLA
                     HEQGFAVLSPEHLTAVANTLTFLFQHTKVWSLLWAESVAGPATFRDTRTVRWGVGVEKS
                     RELARTAGLKVEAEGDVWVAKASAELSAEWSKLTQSTVRIDVETETTRELEFDVPAGGM
                     DIALWQLESRLTRRLVLRPRRHLPPEPLPHWVETAIATPVRSIVMPVNLTRSTTRTPVD
                     A"
     gene            4520..5626
                     /locus_tag="ND450_RS19345"
                     /old_locus_tag="ND450_19345"
     CDS             4520..5626
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015983.5"
                     /locus_tag="ND450_RS19345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19345"
                     /product="radical SAM protein"
                     /protein_id="WP_253327462.1"
                     /sec_met_domain="PF04055 (E-value: 1.6e-13, bitscore: 50.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.8e-09, bitscore: 36.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLVRGENGWWCIGRSATALLPDRLVRGGDLTAEGREQVAGAGLD
                     AVPEPDHYSLTVVTSTGCNLGCSYCFQNTPDGRRRIAPARLDARTVARCVEFTEKKMAE
                     LGVRRLELLLFGGEPLLNPAGCLQVLRAFGARMPVTASMISNGVLLTPRTAARLHEAGL
                     GHLQVTLDGERDRHDRTRVTRGGRPTFDLILANVASAQRHTGLRFTVRVNVTPDVLPHL
                     GTLLDQAAAVLDVPRTSLAIAPVLDYGAGVPAPDARAAEQAVQACARAAELGFRLVRPR
                     DDHCDFCSETDGRLGAVVAPDGTLFSCWDAVGEDHLAVGELDSGYSSRSRARWRRCGGE
                     LPRTQAFSDALDAGVLDVIRARKEVTRP"
     gene            5931..7235
                     /locus_tag="ND450_RS19350"
                     /old_locus_tag="ND450_19350"
     CDS             5931..7235
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007031739.1"
                     /locus_tag="ND450_RS19350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19350"
                     /product="pitrilysin family protein"
                     /protein_id="WP_253327463.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 6.6e-19, bitscore:
                     67.4, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 3.4e-20,
                     bitscore: 71.9, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQRTHQHLVRTQLANGLRVLLAPDRTVPVVAVAVHYDVGMRSEPE
                     GRTGFAHLFEHLMFQGSELLPKLDHAHYVQASGGIFNGSTHLDYTQYHNVLPSNALERA
                     LFLEADRMRAPNLNAENLRVQIDVVKEEIRANVTNKPYGCFPWVTLPGVLFDSFANSHD
                     GYGSFDDLDSATVEDARQFFDRYYAPANALLTLCGDFDADEALAMVERHFGPIPFRPRP
                     SRPDFAEPEITGERRTVKYDPHAPLPAVAAGWRVPDPIGQWDEYLPYLLLADVMSDDGP
                     ACRLHRRLVRQDGLATSHRCYLGMLGDPLDTGHPTALVCSARQTPGTSSQQVLDAVAEE
                     FALVARHGPEERELNRIASRLTTRLLVETDSVLARTQALASLELRHGRAELLGELPALL
                     TAITPEQVARAAARITPDRRAVVELLPASYQEEAA"
     gene            7232..8560
                     /locus_tag="ND450_RS19355"
                     /old_locus_tag="ND450_19355"
     CDS             7232..8560
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017044.5"
                     /locus_tag="ND450_RS19355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19355"
                     /product="pitrilysin family protein"
                     /protein_id="WP_253327464.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 3.2e-07, bitscore:
                     29.5, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 3e-16, bitscore:
                     59.0, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASVVPALRPWPEIISPDVTEDRCANGLRLLALQRPGAPLAEIR
                     LSVPFGSMAPGHLARAWLLSETVLAGTAATGRIGLAERVGELGASLRAEVDHDRLLFSG
                     TVLADRFEDLLAVLAEVVREATYPDREVLAERGRLASRLTAARSQAAIRAREILHRHLY
                     GDHPYGASIPTGAEVDAISAGQLRALHAERVVPDHAVLVVVGLVDPDRAVTAMRRHFAD
                     WRPGGLPVPDLPPLPDEAPAGASRLFHRPGSVQSSIRIGGPALRRDDPLFPALHLANLI
                     YGGYFSSRLVANIREDKGYTYTPRSRIMHSSAGSTLVIEADVATDVTAPALLEMWYELG
                     RLSTLRPSAQELRDVRQFAAGNLAMSIATRSGLATTLVTLLGVGLDLDWIRRSPDLLAE
                     VTASDIYHVGVHLLAPKLLAAVVIGDATKCEEPLQAFGPWVVE"
     gene            8723..9688
                     /locus_tag="ND450_RS19360"
                     /old_locus_tag="ND450_19360"
     CDS             8723..9688
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS19360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_19360"
                     /product="hypothetical protein"
                     /protein_id="WP_253327465.1"
                     /transl_table=11
                     /translation="MSLRDLGFDALQEGVYRSLLADPLRDNSTLASLLLTDETAVRNAL
                     AGLLALGVVEVAATAPCGYAPGDPEVVVGELIERLEQETLRRQQKIGGTRTELAGLAAG
                     FRHDARTVEVEHITEPERIRERLAELCFFTRSSVYAVQPARASSEAARAEASRLDNRSL
                     GRGVTMRIIYDERVLRAERTRARLGERTASGAQIRFLPGPLARLILLDERIAIVPSDPT
                     DAGSGALVVHQPGIVSELVGRFRQLWDGAQDFAEPAGAPSDDDRSVLRMLASGLTDELV
                     ARQIGVSVRHLRRRIARLMDELGADSRFQAGMAAARRGWI"
     misc_feature    complement(9996..10010)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.14"
                     /tool="antismash"
     gene            10001..12535
                     /gene="lanKC"
                     /locus_tag="ND450_RS19365"
                     /old_locus_tag="ND450_19365"
     CDS             10001..12535
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="ND450_RS19365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19365"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_253327466.1"
                     /sec_met_domain="micKC (E-value: 7.4e-127, bitscore: 423.5,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 4.8e-08, bitscore: 31.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 0.00057, bitscore:
                     17.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSISLVHADPEFYAPLSRTTRRGTEYTATGMPADWSRHHQDVWTG
                     WYPPHKLGGVTDGWKIHLSARANRAQHVLDVAAPIFAAHGVGFKHLSCSLYFVVTHHKH
                     AERSQSGKFCAAYPPDAATAEALMRDLAAAFDGEEGPYVLSDRRFGDSRVVHYRYGAFV
                     ARRRLTAQGWHELLVLDAAGRSVPDVRGTRFSTPEGITDPFAESSVDAPKRTGAPEFGG
                     VRFEKALRHSNGGGAYQGTDVATGRTVFVKESRGHHGLVSPTSASQDRLRNEYEVLREL
                     HRAGSGFAPEPVRYFRHLENEFLVTEFVPGRSLRSWWVEHNPIIWSTATDDDFLAYYAR
                     AAKILDQLTAQLERLHGLGYAFIDLSPDNVLVDDEDRVRLIDFETAARLGGPLTPIGTP
                     GFFPADPLRFADDPVRYDDYALSSIALALIAPITTTADLFPGVLAHLKAQLDPHGLVPR
                     KMWALATQVREPDPVPSADEVTSNPWNCLKALRDGLITGLRDTGHPDGVVPLGPRSYAT
                     NRLGFGHGLAGVVHALHVAGTPSDELLDRLCARALAEADDLPPGLVAGQAGVARVLAEH
                     GRIAEAQELLARADEHPLLHGSATLGFGSAGVGLAHLALYRHTGDRAHLDQAVRHAHEI
                     PGSPTELLGRHNAAGLVDGRTGLALFHHHLGVLTGDEDHLARGLGLLHEELDRAELSEG
                     GLLFGVSDRDRRLMPYLSTGTAGVLMVASRYLATTGDERVAAAIPGLLTGLNCSFTHYG
                     GLFDGMAGLSLALHDHGRRHGDQASLDRAQTLAQRLFLYAVPHETGTYVPGEHALRLSG
                     DLWFGSAGVLTVLAGVLDDHPDPLFALDEVER"
     CDS             12561..12674
                     /gene="allorf_4383362_4383475"
                     /locus_tag="allorf_4383362_4383475"
                     /protein_id="allorf_4383362_4383475"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSDVNELQNLADDENTEAGYTNPVEVEPGKSTASIVC"
     CDS_motif       12561..12626
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSDVNELQNLADDENTEAGYTN"
                     /locus_tag="allorf_4383362_4383475_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12627..12674
                     /prepeptide="core"
                     /locus_tag="allorf_4383362_4383475_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-2.10"
                     /molecular_weight="1461.7"
                     /monoisotopic_mass="1460.8"
                     /core_sequence="PVEVEPGKSTASIVC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSDVNELQNLADDENTEAGYTN"
                     /leader_location="[12560:12626](+)"
                     /alternative_weights="1479.7"
                     /alternative_weights="1497.7"
     CDS             12737..12850
                     /gene="allorf_4383538_4383651"
                     /locus_tag="allorf_4383538_4383651"
                     /protein_id="allorf_4383538_4383651"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSDINELQNLADDENTEAGYTNPVEVEPGKSTASIVC"
     CDS_motif       12737..12802
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSDINELQNLADDENTEAGYTN"
                     /locus_tag="allorf_4383538_4383651_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12803..12850
                     /prepeptide="core"
                     /locus_tag="allorf_4383538_4383651_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-2.10"
                     /molecular_weight="1461.7"
                     /monoisotopic_mass="1460.8"
                     /core_sequence="PVEVEPGKSTASIVC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSDINELQNLADDENTEAGYTN"
                     /leader_location="[12736:12802](+)"
                     /alternative_weights="1479.7"
                     /alternative_weights="1497.7"
     gene            12967..14205
                     /locus_tag="ND450_RS19370"
                     /old_locus_tag="ND450_19370"
     CDS             12967..14205
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.5"
                     /locus_tag="ND450_RS19370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19370"
                     /product="MFS transporter"
                     /protein_id="WP_253327467.1"
                     /transl_table=11
                     /translation="MSRDFRYYWSAEVSSTFGSTFTTMAIATLGVIVFNASPSELGFVS
                     AAAILPACVFGLLAGVLGDRLRRPRRVLIGCNAAAASLVLVVALGIGTGAATIWWLAAL
                     CFVLGCIATVVETVYFTHLRSLVPPDRLTAGRARLQTGEYGARTAGQALAGVLISVLGG
                     AFALVVDALTYLVSLVLLTRITAPDQGAPPADAPRSLHREIGEGFRQVAKYPFLRTFGV
                     FTAVRSMSVGALATIVAPFLLRDLHVPLELYGALFAVSGLAGLVGSLAAGRLAERMSLH
                     SLAVLGSAGTVGAAFVLPSAGGPLPVALTIAVLGLALPTVFGAIANVGLSGALTELVPE
                     NALGRAIASLRTIATTAQILGALGGGLLADALGLRPTAWVCAGLALLGCVPLLRAVVVT
                     RGPAPVEEPAVLV"
     gene            14202..15920
                     /locus_tag="ND450_RS19375"
                     /old_locus_tag="ND450_19375"
     CDS             14202..15920
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024846.5"
                     /locus_tag="ND450_RS19375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19375"
                     /product="FAD/NAD(P)-binding domain-containing protein"
                     /protein_id="WP_253327468.1"
                     /transl_table=11
                     /translation="MTAVLAIIGAGPRGTGLLERLAANASLLPAGCEIHVVDPHPAGAG
                     RVWRPDQSPLMLMNSRAADVTMFTDDSVRCAGPITPGPTLAEWSGLDDDVFPTRRQGGA
                     YLRWCFDRAVRAFPRVVRVFVHRTSAVALSDGPRQTVALANGTHVVADVVVLAQGNVGG
                     HRTPGQLAHQDFAARTGGTYLPPSCPGDEDLDRLPAGEAVLVSGMGLAFVDLVVLLTQG
                     RGGRFTRGRDGTLTYHPSGREPVLHAGSRRGVPYLPKPVPPPLADRAPRFFTPALLARA
                     TTPGELVGAACRELVWAHYRELFAAHAERTRMPRDAFASAFAALPITDPALEVLVAQAV
                     PDPADRADTSFLRAPLTRSFPDQAALNTWMRDHMGHAVARATDPRHSAHAAVLHGLLTV
                     SEVLEQAAPTPATARTAAVLSRFAAYLGSGPPPHRLEQLQALTRAGLLHFLGAGLRVTR
                     TDAFTAHTDSLPFAVSARHFVEARLPDPDARTHPLLLPLAHNRTRVPVDPDTFHVLDDT
                     GDAHPRRLALGLFAGGGALGAFSRPGRNAPFFRQNDDTARRVLAELNARTPALTP"
     gene            complement(16321..17817)
                     /locus_tag="ND450_RS19380"
                     /old_locus_tag="ND450_19380"
     CDS             complement(16321..17817)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS19380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_19380"
                     /product="hypothetical protein"
                     /protein_id="WP_253327469.1"
                     /transl_table=11
                     /translation="MASADTGGDGLLGGVGDAVHSIVNGGNGGDSGKGGDATSSNNARS
                     GDSGDSGNSGSTGGNSAYGLCVLAECHTNVSSGDSGDTGATGSTGDASNHSATAGGNSG
                     SAGDGGDATAAGRSGDSGANAGNGGNSGDGGNASSSNNATSGNSGDSGNSGDTGGNSAY
                     GVCVLAECHTNVSSGDSGDTGATGATGDASNHSTTVGGNSGSAGDGGDATAVSKDQKWG
                     HNNNGSTEATAGNGGNSGNGGNATSSNNATTGDSGDSGSSGDTGGNKAVVRTTGSEQGH
                     GWNRDEKSWDGDKSWTTVTSGDSGDTGATGSTGDAWNHSTTVGGNSGPAGDGGDAWAVT
                     EQGKSWKHHGKWSKHSDNGSTEATAGNGGDSGKGGNATSSNNATTGDSGDSGNSGDTGG
                     NSAVVKNENKNNGWKHDSWKKHSWKHDGWKHDGWKHDGWKNHGTQSWTEVTSGDSGDTG
                     ATGSTGDASNHSTTTGGHSGPAGDGGDAASWTHGKHSVKA"
     misc_feature    17908..17922
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            complement(17948..18736)
                     /locus_tag="ND450_RS19385"
                     /old_locus_tag="ND450_19385"
     CDS             complement(17948..18736)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS19385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_19385"
                     /product="hypothetical protein"
                     /protein_id="WP_253327470.1"
                     /transl_table=11
                     /translation="MKLTCSTALKRTFGVAGFLIGFGLLSAGVASADDGGSPGPLGGVA
                     GLVAPVTDSVAPLTRDVTAVAEPVLEPVLEAAEPVTEPVLEPLAPVVDTATRALDPVLE
                     PLRPVTAPLLTPVVNAVRDVPLVPRIAEPLVAQPSAAAEVPPPVSVAPETPDVPVVVPQ
                     THVVALPEQVAVAGTPQRQPISAPEAAPPTEAPSPPSPGVPFAPTGTTGSASSTGSTGL
                     ALSDLPAERGVHAGDGSLVVVTDHQVHGSWCYYYGRNHPS"
     misc_feature    18848..18861
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.25"
                     /tool="antismash"
     misc_feature    18850..18864
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.15"
                     /tool="antismash"
     misc_feature    18852..18865
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.53"
                     /tool="antismash"
     misc_feature    18852..18866
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.8"
                     /tool="antismash"
     misc_feature    complement(18853..18866)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.74"
                     /tool="antismash"
     misc_feature    complement(18854..18867)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.21"
                     /tool="antismash"
     misc_feature    18854..18868
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.9"
                     /tool="antismash"
     misc_feature    18953..18968
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.83"
                     /tool="antismash"
     gene            complement(19096..21390)
                     /locus_tag="ND450_RS19390"
                     /old_locus_tag="ND450_19390"
     CDS             complement(19096..21390)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.5"
                     /locus_tag="ND450_RS19390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19390"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_253327471.1"
                     /transl_table=11
                     /translation="MSPMPDTPLLLDDGTARTLERARGADHVVLTGPAGCGKTTLLRAF
                     AQPIAVDDGHALGEDEADRLLDEVRAGGRLVLAHRPWPDNRALGRLVGALPGTVVRVRL
                     RPLTQGQVRSLAARVLGAEVSDEVAGRLHERTGGTPGFVLDELSPEPRGAFARHLDELP
                     VAANDLLLARALGAPFDVELLAAVLALDPHVVSESAEALRSAGLLRIDGAPLPVAAEAA
                     EALAPAEQRADLLRRLALTQVERSQPVAGYARPLLELGVVDPGLADVFIAAGHEVVDDD
                     PALAARVFAAAGPGSSALLARARALSGDLDGAVDVVDLEHADADALLVAATVLTLRGQV
                     GRGGELLRRSDNGLALGFAVTGLLGAGRLEEARAVQSGAHPAASLTDTLGHRLAGVVLD
                     TVTGPPMAAVAAAVATAGVNQAGSRASVQPDSPTALAALVCVHAGELSVARSLLAKAVR
                     GDDGRGLHADRHQLLLACVDLFRGDVEEARRLSRPDLSREPREALFAAALELGVTRRAG
                     DLHALRAAWEPAQQALVVHPVDLYTLLPLTEIAVAAARIGQFHRVETHLDEAWTLLGDL
                     GDPPLWTVLPRWNAFHAALLLGDHPAAEEHLAALDTAADALPFGRALATAAHCWSEAGH
                     GDVDHLRVESAARELHAHGLRADAARLAGHAAMHTTDRRAMTQLLDIARQFHGTNGGQG
                     NGGAEVLSDREQEVAALVRDGLTYREVGDALFISAKTVEHHVTRIRNKLGARNRRELER
                     ALEDVSLPAPR"
     gene            21625..22398
                     /locus_tag="ND450_RS19395"
                     /old_locus_tag="ND450_19395"
     CDS             21625..22398
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038175.1"
                     /locus_tag="ND450_RS19395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19395"
                     /product="IniB N-terminal domain-containing protein"
                     /protein_id="WP_253327472.1"
                     /transl_table=11
                     /translation="MTLPQTLHDFTLNLLSDPEARSAFQLDPQGSLDAAGLGDVHPADI
                     QELLPLVLDFAPVTSLGDFGSTISGLDLDQQLDLMSTLQNTVGQQLDDNTVLGAVSGLT
                     AAVHGVTNGFDVLSDPSSALDVVAGTEITDVTKTVTDLDVTNTVGDITNGTDVLDTTHV
                     TDVVGDVTSGVQTGDLGVNDVLSGDVTSAIGTVTGNDLSLDHVGNVTDVVSHVGNVGDV
                     TGVGSVGDLGKIGDISGELGDVNVGGVLNDLDLSL"
ORIGIN
        1 gcggcgggcg accacccggc cctggccgcg ttcatcacgc agatgcagga cacctcgagc
       61 ggcttcccgt cctaccacgt ggtgcgcacc cggtacttcg acgaccggat caggtacgcg
      121 ctggacaacg gcgtgcggca ggtcgtggcc ctcgcctcgg gcgtggacgg ccgcacgacc
      181 cgcctgccgt gcccgcgcga cacccgctgg ttcgagctcg acctgccggc catgaccgag
      241 ttcaagacga ccctggtcga gcagtccggc ctgactccca cctgcgagcg gatcggggtg
      301 gccgccgacc tcaggacgga ctgggccgcg ccgctgcggg cggcggggtt cgacccccgc
      361 aggcccaccg cgtggctggt cgagggcgtg ctgatgtacc tcacgcccga cgagggtgac
      421 gcgctcctgg acgcggtgac cgcgctgtcc gcccccggca gccacctgct gctcgaacac
      481 ctgcaggtct cgatgctcgg cgaccggggc acgcgggtgc ggggcgggct gggcaagcac
      541 ggggtcgtgt tcaccgcggc ccgcgacgac ctggaggact ggctgggcgc gtccgggtgg
      601 cgggcggcgg tgcacgcggg tgtggatccc gcgatcgggc acggccggtc cgtcgcgccg
      661 gtgcccgcgg cctggctggc ggccgcgacg cgcgccgccc gcgcgggacg ctgaccgcgg
      721 cacgccgtcc ccgaccgcgg tccggttccg tccactgtgg tctgaacaac gcccggtgtg
      781 aacggccatc gcgcccaccg gaacgacttt gtccacatcg gacggaattt caccgtgcgc
      841 gcccgcccgc gaagatcgtt gtcccgaagg caaattccac gtggacgcga acgtaacacc
      901 gcgcctgtac tcggcgactg accggtcgac tccaaggtga agacggccga acgggcgcac
      961 acgaaccgaa ggaaatccca tgaccagcag agaagaggcc gagagactcc tctcctccct
     1021 cggagacgag gacctcgtcg aaatcgactc caacgggaag atctacgcgg tcggcaagtc
     1081 cccggccgcc gcgtcgggca agtcgatcgc gggcatctcc gaccagaggg gcgagtacgg
     1141 gaaggcgggc cggtggactt ccgggtgacg aggtcgctcc tcgtcagcgc cacccccgac
     1201 ggccgcctcg ccgccgagaa gaagatcctc gccgcgcact tcccgcagtt cacgctctcc
     1261 accaggaccg acgctttcgc cgtggcccgc gggcagctcg agacgttcac cgggcggaag
     1321 taccgcgtcg agatcacggc ggactcgtcc tacccgcact cgctgcccga gatccacccg
     1381 gtcggctgga ccctcaggcc gaacccgcac atcatccgcg gcgggctgtg cgtgatgcgc
     1441 gcgaaccagt gggcctcgtt catgtccgtg gcctttctcg tcgcgaagtc cgctctgtgg
     1501 ctcaacaagt acgaggtgtt cctcgacaag ggcatctggc cgggtccgga gcagcacgag
     1561 cacggcccga tctacaaggt gaggaagtgg tggcatgagc tctgacacca gcttcgacac
     1621 gtcccggatc gactacctgg tgagcggggc cggactgcgc gacaggaagg tcgtcgtcgt
     1681 cggactgggc agcggcggcg ccgtcgtgct ggagcggctc ggcatgaccg gcgtcgggag
     1741 gtggtcgctc tacgacccgg acgcgctgga cccggtgaac ctcgtcaagc acccggcgcg
     1801 gcggtcggac ctcgggcgcg cgaagaccga catcgcgcgg acctggctcc tcgacaggaa
     1861 cccggcctgc acgatcgaac ggatcggcgg gaacgtggtg ggggacgaag ggttccccgc
     1921 cgacgtggcc ggcgcggatc tcgtggtgtg cgcggtcgac acgcccgagg cgcgcagctt
     1981 cgtgaacgaa gtctgcgtgc gcgaacggac gccctgcgtc ttcggttccg tgttccgcac
     2041 cgggatgggc ggcgaggtct acgcctacct gccaggggag gccggctgcc acgactgcaa
     2101 ggtgcggttc agcctcgaac aggggcgcga cgtcgagaac tggctcgacc tcaccgacga
     2161 ggagacccgg cggatctacg gggtcggcga ggcggacttc tccgcgtccg gcctggccgc
     2221 cgacatctcg gtcgtggcgt cctaccacgc ccactacgtg atctcgctgc tcgcgggacg
     2281 ggggtcgcgg tacctcacgg tgccgtcctt caactggctg accctctcgc tgcgtcgcgt
     2341 cgacggtctc ttcaacgcca tgtacgacac ctcacgcgtc ctgctgcgcc cgcgggcgga
     2401 atgccacctg cggtgcggcg gcggggaagg gagatgaccg gcgtgggcgc gagaggtccc
     2461 ggagcccctc aggtgatcgt gccggtgcag gtcgccgagc ggttcacgaa ggagatcaac
     2521 gaccacccgc acgtcgaggt gggcgggaag tacgtcggct tcatcagggg agtcgcgcgg
     2581 cacgacaccc tcgaggagcg gctgcgcgcc gtgcccgggc tgacgttcga ggtcgtggac
     2641 tacatcgacg acgggccggc ggcgcagcgg accgcggggt tccaccgcgg agacccggac
     2701 tggcagaccg ccgagttccg caggctcgag gcggcgcggc cggacatcga gcaactgggc
     2761 agctggcaca gccaccaccc gaacggactg cgggagctga gttcggggga cgtgcacggc
     2821 taccaggaga cggtcgacga cctgggccac aaccacgact acttcttcgt gagcctgggc
     2881 gtcgacctga aggggttcgt cacggcgagg cactacctct tcatccgcgg cagcaagaag
     2941 tacgtggaac tgcccatgtc ggcgttccag atcacagacg gcgcaccgga tccggcggtc
     3001 ccgcgggaga cggaaccaga agcccccgga tccccggcgc ctcccgaacc gcgggagcag
     3061 gcgggacccg aggcgccccg taccgaggag actcccgaac cggcgccgga cccgccgccg
     3121 cgagaggtac cccggcaggc gcggacgcag ccgcgcgccg agaccgggga gcacctgtcg
     3181 gtgcggggct ggaccgactc ccggccgggc ctggacgcgc tgcgcgccga gcgcgaacag
     3241 ctgcgcagcc ccgagttcgc ccacgtccgg ctgagcatcg gccagggccg cctgctggca
     3301 cggggctggc tcgacacgaa ggcgggccgg gtgtcgatgt ccctgctcta cccgtccgcg
     3361 atcggcggcg acgacgggct cctcaagctc agcacgctgg acgtgcccgg catcgacgtg
     3421 accctgtccg ggccgcagac caggaacctc gtcaccgcga gagtgctgat cggccacttc
     3481 atccgttacg cggacgtgca ccgcccgctg atgcggaagg acccggacag gcagtcgttg
     3541 ctccaatcga tcaagaactg gttctgaacg gaaggacgac ccgcgtggag cacaacgagc
     3601 caccggactt ccccggctcc gccatcggaa gcgggatgga cctgctggcg gagctctcgt
     3661 caccgtggac gacggcgcgt gccatcacgg cgccggggct gacccgccag ttgctggcgc
     3721 acgagcaggg cttcgccgtg ctgtccccgg agcacctcac cgcggtggcg aacacgctga
     3781 ccttcctctt ccagcacacc aaggtgtggt cgctgctgtg ggcggagtcc gtcgccggac
     3841 ccgcgacgtt cagggacacc cgcaccgtgc gctggggagt gggcgtcgag aagagcaggg
     3901 agctggcgag gaccgcgggg ctcaaggtcg aggcggaagg cgacgtgtgg gtcgccaagg
     3961 cgtcggccga actgtctgcg gagtggtcga agctcaccca gtccaccgtc cgcatcgacg
     4021 tggagacgga gaccacccgg gagctcgagt tcgacgtgcc ggcgggcggc atggacatcg
     4081 cgttgtggca gctcgagtcc cggctgacgc ggcgcctggt cctccgcccc cggcgccacc
     4141 tcccgccgga gcccctgccg cactgggtgg agaccgccat cgcgacgccc gtgcgttcga
     4201 tcgtgatgcc ggtcaacctc acgcggagca ccacccgcac gccggtggac gcctaggagc
     4261 ggttccgcca ccaggtccgc aagctgccat cacggcgtcc cctacctgcc gttcgatccg
     4321 ctgtcccccg ccctcccccc aggcgacagt ggaggagacg aacgagcgga aggaggtggg
     4381 atcagatgct caagaccccg gacttcggtg acgagtacgg cgaccaggac gtgcgctgcg
     4441 tcggcaccgg tggctaccac gacctcggcg actactacgg gatctgatcc acccgcggat
     4501 gccgagggag gtgcgggacg tgcgactggt gcgaggcgag aacggctggt ggtgcatcgg
     4561 ccggtcggcg acggcgttgc tgccggaccg gttggtgcgg ggcggtgacc tcaccgcgga
     4621 aggccgggag caggtggccg gggcaggcct ggacgcggtg ccggaaccgg accactacag
     4681 cctcaccgtc gtgacgtcca ccggctgcaa cctcgggtgc tcctactgct tccagaacac
     4741 cccggacggc aggcggcgca tcgctcccgc acgactcgac gcgcgcaccg tcgcgcgctg
     4801 tgtcgagttc accgagaaga agatggccga actgggcgtg cggcggctgg agctgctcct
     4861 gttcggtggt gagccgttgc tcaaccccgc cgggtgtctg caggtgctgc gggcgttcgg
     4921 tgcgcggatg ccggtcaccg cgagcatgat cagcaacggc gtgctgctca cccctcggac
     4981 ggccgcacgg ctgcacgagg ccgggctcgg gcacctccag gtcaccctgg acggcgagcg
     5041 cgatcggcac gacaggacac gcgtgacgcg cgggggcagg cccacgttcg acctcatcct
     5101 ggcgaacgtg gcctcggccc agcggcacac cggcctccgc ttcaccgtgc gcgtcaacgt
     5161 gacaccggac gtcctgcccc acctcggaac gctcctcgac caggcggccg cggtgctcga
     5221 cgtccccagg accagcctcg cgatcgctcc cgtgctcgac tacggcgccg gcgtcccggc
     5281 accggacgca cgggccgcgg aacaagcggt gcaagcctgc gccagggcgg cggaactcgg
     5341 gttccggctc gtccgcccgc gcgacgacca ctgcgacttc tgctccgaga ccgacggccg
     5401 cctgggcgcg gtcgtggccc cggacggcac gttgttcagc tgctgggacg cggtcggcga
     5461 ggaccacctc gccgtcggtg agctcgactc gggctacagc agccgatccc gtgcgcgctg
     5521 gcgccgctgc ggcggcgaac tcccgcgcac acaagcgttc tccgacgcac tcgacgccgg
     5581 agtgctcgac gtcatccgcg cgcgcaagga ggtgacccga ccatgaccga acccgagcac
     5641 cacgacgacg agacgccctc ggcgccgaac ttcatcgaac tgctcgaggc cgacgaggag
     5701 ctgaccggcc ccggcctctg cgttccgttc cgctagtagt ggtgtgtccc aggaggttgg
     5761 cgaggtaatt cacgctcagc agggcgcctc gcggcaccgc ccccacgccc ccgtaccacc
     5821 agtacgacga cgtgggggcg gcaccacgat gcacccgtct gaccgcgaat tcccccggca
     5881 acctcctgcg ccacaccact cccccacacg agcaccggaa ggagacggcc gtgcaaagaa
     5941 cacaccagca cctggtccgc acccagctgg ccaacgggct gcgggtgttg ctcgcacccg
     6001 accgcaccgt cccggtcgtc gccgtcgcgg tgcactacga cgtgggcatg cgctccgagc
     6061 cggagggccg caccgggttc gcgcacctct tcgagcacct gatgttccag ggttcggagc
     6121 tgctgccgaa gctcgaccac gcgcactacg tgcaggcgtc cggcgggatc ttcaacggca
     6181 gcacccacct cgactacacg cagtaccaca acgtgttgcc cagcaacgcg ttggagcgcg
     6241 cgctgttcct cgaagccgac cggatgcgcg cgccgaacct caacgcggag aacctgcgcg
     6301 tgcagatcga cgtcgtgaaa gaggagatcc gcgccaacgt caccaacaag ccgtacggct
     6361 gcttcccgtg ggtgacgttg ccgggagttc tcttcgacag cttcgcgaac tcgcacgacg
     6421 gttacggctc gttcgacgac ctggactcgg cgaccgtcga ggacgcgcgc cagttcttcg
     6481 accgctacta cgccccggcg aacgcgctgc tgacgttgtg cggcgacttc gacgcggacg
     6541 aggcgctcgc gatggtggaa cgccacttcg ggccgatccc gttccgcccc aggccttccc
     6601 ggccggactt cgcggaaccg gagatcaccg gcgagcgccg cacggtcaag tacgacccgc
     6661 acgcgccgct gcccgccgtg gccgcggggt ggcgggtgcc cgacccgatc ggccagtggg
     6721 acgagtacct gccgtacctg ctgctcgccg acgtgatgtc cgacgacgga cccgcgtgcc
     6781 ggctgcaccg caggctggtg cgccaggacg gcctcgccac gagccaccgc tgctacctcg
     6841 gcatgctcgg cgacccgctc gacacgggcc acccgacggc gctcgtgtgc agtgcccggc
     6901 agacgcccgg cacgagctcg cagcaggtgc tcgacgcggt cgcggaggag ttcgccctgg
     6961 tggcgcggca cggtccggag gaacgcgagc tgaacaggat cgcgagccgc ctcaccaccc
     7021 ggttgctggt cgagacggac tcggtgctcg cgcgcacgca ggcgctggcg tcgctggaac
     7081 tccgccacgg ccgtgccgaa ctgctcgggg agctgcccgc cctgctcacc gcgatcacgc
     7141 ccgagcaggt ggctcgggcg gccgcgcgca tcacccccga ccgccgggcc gtggtcgaac
     7201 tgctgcccgc ctcgtaccag gaggaggcag catgacggcg agtgtcgttc ccgcgttgcg
     7261 gccgtggccg gagatcatct ccccggacgt cacggaagac cgctgtgcca acgggttgcg
     7321 gctcctcgcg ctgcagcggc cgggcgcgcc gctggccgag atccggctga gcgtcccgtt
     7381 cggttcgatg gcgccgggtc acctggcccg cgcgtggctg ctgtcggaga cggtgctggc
     7441 gggcaccgcg gccaccggcc ggatcgggct cgccgaacgc gtcggcgagc tgggggcgag
     7501 cctgcgggcc gaggtcgacc acgaccggct gctgttcagc ggcaccgtgc tcgcggaccg
     7561 gttcgaggac ctgctggccg tgctcgcgga ggtcgtgcgg gaggcgacct accccgaccg
     7621 ggaggtgctg gccgaacgcg ggcggctcgc gtcgcggctg acggcggcgc ggtcgcaggc
     7681 cgccatccgg gcgcgagaga tcctgcaccg gcacctgtac ggcgaccacc cctacggcgc
     7741 gagcatcccg accggcgccg aggtcgacgc gatctccgcc ggacagctgc gggcgctgca
     7801 cgccgaacgg gtcgtgcccg accacgcggt gctggtcgtc gtcggcctgg tcgatccgga
     7861 ccgggccgtc acggcgatgc gccgccactt cgcggactgg cggcccggcg ggctccccgt
     7921 gccggacctg ccgccgctgc cggacgaggc ccccgcgggg gcgtcccggc tgttccaccg
     7981 gcccggctcg gtgcagtcgt cgatccggat cggcgggccc gcgctgcgcc gcgacgaccc
     8041 gctgttcccc gccctgcacc tcgcgaacct gatctacggc gggtacttct cgtcgcggct
     8101 ggtggcgaac atccgcgagg acaaggggta cacctacacc ccgcgcagcc ggatcatgca
     8161 cagcagcgcg gggtccacgc tcgtgatcga ggccgacgtc gccaccgacg tgaccgcgcc
     8221 cgcgttgctc gagatgtggt acgagctggg caggttgtcg acgttgcggc cgagcgccca
     8281 ggagctgcgc gacgtccgcc agttcgccgc cggcaacctc gcgatgtcga tcgccaccag
     8341 gtcgggtctc gccacgaccc tggtgacgct gctgggggtc ggcctcgacc tcgactggat
     8401 ccggcgcagc cccgacctgc tcgccgaggt gaccgcgtcc gacatctacc acgtgggcgt
     8461 gcacctgctg gcccccaaac tcctcgcggc cgtcgtcatc ggggacgcga cgaagtgcga
     8521 ggagccgctg caggcgttcg gcccctgggt ggtcgagtag ccgttctacc tgcgcaaagc
     8581 ccggtcctgc ccccgcggga ccgggctttt gcgtgttccg cccccacacc ccgcagcgaa
     8641 tatggggagc cactacccat gtgaccgcgc aaccaggtga cgcacagtct cctcaggcgg
     8701 tggaactgat cggggtggtg ggatgtcgct gcgtgacctc ggcttcgacg cgctccagga
     8761 gggcgtgtac cggagcctgc tggccgatcc gttgcgggac aacagcaccc tcgcgtcgct
     8821 cttgctcacg gacgagaccg ccgtgcggaa cgcgctggcc ggactgctcg ccctcggtgt
     8881 cgtggaggtg gccgcgaccg ccccgtgcgg gtacgcgccc ggtgaccccg aggtcgtggt
     8941 cggcgagctg atcgaacggc tggagcagga gaccttgcgg cgccagcaga agatcggcgg
     9001 cacgcgcacc gaactggcgg gcctcgcggc ggggttccgg cacgacgcgc gcacggtcga
     9061 ggtcgagcac atcaccgagc ccgaacggat ccgcgagcgg ctcgcggagc tgtgcttctt
     9121 cacccggtcc agcgtgtacg cggtgcagcc ggcgcgggcg tccagcgagg cggcccgcgc
     9181 ggaggcgtcc cggctcgaca accgcagcct gggccgcgga gtgacgatgc ggatcatcta
     9241 cgacgagcgg gtgctgcgcg ccgaacgcac ccgtgcccgg ctcggtgagc gcacggcgtc
     9301 cggcgcgcag atccggttcc tgccgggtcc gctcgcgcgg ctgatcctgc tggacgaacg
     9361 gatcgcgatc gtgccgtccg atccgaccga cgcgggctcc ggcgcgctgg tcgtgcacca
     9421 gcccgggatc gtgagcgagc tggtcgggcg gttccggcag ttgtgggacg gcgcccagga
     9481 cttcgccgaa cccgccggcg cgccgtccga cgacgaccgg tccgtgctgc ggatgctcgc
     9541 ctccggactg accgacgagc tcgtcgcccg gcagatcggc gtgtccgtgc ggcacctgcg
     9601 ccggcggatc gcgcggctca tggacgaact cggggcggac agccggttcc aggcgggaat
     9661 ggcggccgcg cggcgcggct ggatctgaga cctcattgcc ctgacaacag caggtgacac
     9721 tgttcaggag gaaacatggt gcgcaaggcg ggatcgaacg ggatcggcga ggacgacgac
     9781 gtgatcggcg cgttcggctg ggactgatag accggcgcgg accaagggcg ggtacctgcg
     9841 ggtgcccgcc cttttcgtca cccgcaacgg ggtcatcttg ttgtccgcga acggtccgga
     9901 agctgacgcg ccacgacctt ccgaacccgt tggcaggcaa gcagaattgt ttccagagca
     9961 agggaaaagc ccgaaggaat ccggagaggg gaacgagaaa atgagcatct cactcgtgca
    10021 cgccgatccg gagttctacg ccccgctcag ccgcacgacc cggcgtggca ccgagtacac
    10081 cgcgacgggc atgccggcgg actggagccg gcaccaccag gacgtgtgga cggggtggta
    10141 cccgccgcac aagctcggcg gcgtcaccga cggctggaag atccacctgt cggcccgtgc
    10201 gaaccgcgcc cagcacgtgc tggacgtcgc cgcgccgatc ttcgcggcgc acggcgtggg
    10261 gttcaagcac ctgagctgct cgctgtactt cgtggtgacg caccacaagc acgccgaacg
    10321 cagccagtcg ggcaagttct gcgccgccta cccgccggac gccgcgaccg ccgaggcgct
    10381 catgcgcgac ctcgccgccg cgttcgacgg tgaggaaggt ccttacgtgc tcagcgatcg
    10441 ccggttcggc gactcgcggg tcgtgcacta ccgctacggc gcgttcgtcg cccggcgcag
    10501 gctcaccgcg cagggctggc acgagctgct ggtcctcgac gcggccgggc ggagcgtccc
    10561 ggacgtgcgc ggcacgaggt tcagcacgcc cgaaggcatc accgacccgt tcgccgagtc
    10621 ctctgtggac gcgccgaaac gcactggcgc gccggagttc ggcggtgtgc ggttcgagaa
    10681 ggcgttgcgc cacagcaacg gcggcggcgc ctaccagggc accgacgtcg ccaccgggcg
    10741 cacggtgttc gtgaaggaga gccggggcca ccacggcctg gtgagcccca ccagcgcgag
    10801 ccaggaccgg ctgcgcaacg agtacgaggt gctgcgggag ctgcaccgcg ccggttccgg
    10861 cttcgccccc gaaccggtgc ggtacttccg ccacctggag aacgagttcc tggtcaccga
    10921 gttcgtgccg ggacgatcgc tgcgctcgtg gtgggtcgag cacaacccga tcatctggtc
    10981 caccgcgacc gacgacgact tcctggccta ctacgcacgg gccgcgaaga tcctcgacca
    11041 actgaccgcg cagctggaac ggttgcacgg cctgggttac gccttcatcg acctgagccc
    11101 ggacaacgtg ctcgtggacg acgaggacag ggtccggctc atcgacttcg agacggccgc
    11161 ccgcctcggc ggaccgctga cgccgatcgg cacgccgggg ttcttcccgg ccgacccgct
    11221 gcggttcgcc gacgacccgg tgcgctacga cgactacgcg ctctcctcga tcgcgctggc
    11281 gttgatcgcg ccgatcacca cgacggccga cctgttcccc ggcgtgctcg cccacctgaa
    11341 ggcgcagctc gacccgcacg gcctggtgcc gcggaagatg tgggcgctgg cgacgcaggt
    11401 ccgcgagccc gaccccgtcc cgtccgcgga cgaggtcacc tcgaacccct ggaactgcct
    11461 gaaggcgttg cgcgacggcc tgatcacggg tctgcgcgac accgggcacc ccgacggcgt
    11521 ggtgccgctc ggtccccggt cctacgccac caacaggctc ggcttcggcc acgggctggc
    11581 gggcgtcgtg cacgccctgc acgtggcggg aacgccgtcg gacgaactgc tggaccggct
    11641 gtgcgcccgt gcgctggcgg aggcggacga cctgcctccc ggactcgtcg cgggacaggc
    11701 gggcgtggcc cgcgtcctcg cggagcacgg caggatcgcc gaggcgcagg agctcctggc
    11761 ccgggcggac gagcacccgc tgctgcacgg gtccgcgacg ctcggcttcg gctccgccgg
    11821 cgtcggactc gcccacctcg cgctgtaccg gcacaccggc gaccgcgccc acctggacca
    11881 ggcggtccgg cacgcccacg agatccccgg ctcgccgacc gagctgctcg gccggcacaa
    11941 cgccgccgga ctcgtcgacg gacggaccgg gctcgcgttg ttccaccacc acctcggtgt
    12001 gctgaccggg gacgaggacc acctcgcgcg gggactgggt ctcctgcacg aggaactgga
    12061 ccgcgccgaa ctctccgagg gcggactgct gttcggggtc tcggaccgcg accgcaggct
    12121 gatgccgtac ctgagcaccg gcaccgcggg tgtgctgatg gtggcgagcc gctacctggc
    12181 cacgaccggc gacgagcgcg tcgccgccgc gatcccgggc ctgctgacgg ggctcaactg
    12241 ctcgttcacc cactacggcg gcctgttcga cggcatggcg ggactgagcc tcgccctgca
    12301 cgaccacggc cgcaggcacg gcgaccaggc gagcctggac cgtgcgcaga ccttggcaca
    12361 gcgtcttttc ctctacgccg tgccgcacga gaccgggacg tacgtccccg gtgagcacgc
    12421 actgcgcctc agcggcgacc tgtggttcgg gtccgccggg gtgctgacgg tgctcgccgg
    12481 agtgctggac gaccacccgg atcccctgtt cgccctcgac gaagtcgagc ggtagcaaga
    12541 aaacccctga ggaggcagtc atgtccgacg tcaacgagct ccagaacctc gccgacgacg
    12601 agaacaccga ggccggctac accaacccgg tcgaggtcga gcccggcaag agcaccgcca
    12661 gcatcgtctg ctgacctggc cccacccgct cttcccgcac cacagcaagc acttcacctc
    12721 aacgaaggag acggacatgt ccgacatcaa cgagctgcag aacctcgccg acgacgagaa
    12781 caccgaggcc ggctacacca acccggtcga ggtcgagccg ggcaagagca ccgccagcat
    12841 cgtctgctga cctgaccttc cacaggtcac gccgtgccac ggggcggagg cgggggaact
    12901 cccccgctct ccgccccgaa gctctttccg cccaggatga cttctccgcg tcgcaggagg
    12961 accagcgtga gccgcgattt ccgctactac tggtcggccg aggtgagctc caccttcggt
    13021 tcgacgttca ccacgatggc gatcgccacc ctcggcgtca tcgtgttcaa cgcgtcgccg
    13081 agcgagctcg gcttcgtcag cgcggccgcg atcctgcccg cctgcgtctt cggcctgctg
    13141 gccggtgtcc tcggcgaccg cctgcgccga ccgcgccgcg tgctgatcgg ctgcaacgcc
    13201 gcggccgcct ctctggtgct cgtcgtcgcg ctcggcatcg gcaccggtgc cgccacgatc
    13261 tggtggctcg ccgcgctgtg cttcgtgctc ggctgcatcg cgaccgtcgt cgagaccgtc
    13321 tacttcacgc acctgcgcag cctcgtgccg ccggaccggc tgaccgcggg ccgcgcccgg
    13381 ttgcagacag gcgagtacgg cgcccgcacg gccgggcagg cgctcgcggg tgtgctgatc
    13441 tccgtgctgg gcggcgcttt cgcgctcgtg gtcgacgcgc tgacctacct cgtcagcctc
    13501 gtcctgctga cccgcatcac cgcacccgac cagggcgccc cgcccgccga cgcgccgcgg
    13561 tcgctgcacc gcgagatcgg cgagggtttc cgccaggtgg cgaagtaccc gttcctgcgc
    13621 acgttcggcg tgttcacggc ggtgcgttcg atgagcgtcg gcgcgctcgc gaccatcgtc
    13681 gcgcccttcc tgctgcgcga cctgcacgtg ccgctggagc tctacggcgc gttgttcgcg
    13741 gtcagcggcc tggcggggct cgtcggctcg ctggcggccg ggcgcctcgc cgagcgcatg
    13801 agcctgcact cgctggcggt gctgggaagt gcgggcaccg tcggtgccgc cttcgtgctg
    13861 ccgtcggcgg gcgggccgct gcccgtcgcc ctcacgatcg ccgtgctggg cctggcgctg
    13921 ccgaccgtgt tcggcgcgat cgccaacgtc ggcctcagcg gcgcgctgac cgagttggtg
    13981 cccgagaacg cgctcggccg cgccatcgcg agtctgcgca cgatcgccac gacggcccag
    14041 atcctcggcg cgctgggcgg cggcctgctc gccgacgcgc tcggcctgcg ccccacggcg
    14101 tgggtgtgcg cgggcctcgc cctgctcggc tgcgtgcccc tgctgcgggc cgtggtggtc
    14161 acccgcgggc ccgcgccggt cgaggaaccg gcggtgctcg tatgaccgcc gtgctcgcga
    14221 tcatcggtgc cggcccgcgc ggcaccggtc tgctggaacg gctggcggcc aacgcctccc
    14281 tgctcccggc ggggtgtgag atccacgtgg tcgacccgca cccggcggga gcgggccgcg
    14341 tgtggcgccc cgaccagtcc ccgctgatgc tgatgaactc gcgcgcggcc gacgtcacga
    14401 tgttcaccga cgacagcgtc cgctgcgccg gcccgatcac cccgggcccg acgctcgccg
    14461 agtggtccgg gctggacgac gacgtcttcc cgacccgccg gcagggtggc gcctacctga
    14521 ggtggtgctt cgaccgagcc gtgcgcgctt ttccgcgcgt tgtcagggtt ttcgtgcacc
    14581 ggaccagcgc cgtggccctc tcggacggcc cgcgccagac cgtcgcgctg gcgaacggca
    14641 cgcacgtggt cgccgacgtg gtcgtgctgg cgcaggggaa cgtgggcggt caccgcaccc
    14701 cgggccagct ggcgcaccag gacttcgccg cccgcaccgg cggcacgtac ctgccgccgt
    14761 cgtgccccgg tgacgaggac ctcgaccgcc tgcccgcggg cgaggcggtc ctggtgtccg
    14821 gcatgggtct ggcgttcgtg gacctggtcg tcctgctgac gcagggccgg ggcggccgct
    14881 tcacccgcgg ccgcgacggc acgctgacct accacccgag cggccgggaa ccggtgctgc
    14941 acgcgggatc ccgccgaggc gtcccctatc tgccgaagcc ggtgccgccc ccgctggccg
    15001 accgtgctcc ccgcttcttc accccggcgc tcctcgcccg cgccaccaca ccgggcgaac
    15061 tggtgggcgc cgcgtgccgc gaactcgtct gggcgcacta ccgcgagctc ttcgccgcgc
    15121 acgccgaacg gacccgcatg ccgcgggacg ccttcgcgtc ggcgttcgcc gcgctgccga
    15181 tcaccgaccc ggcgctggag gtcctggtcg cgcaggccgt tcccgacccg gccgaccgcg
    15241 cggacacgag cttcctgcgc gctccgctga cccgctcgtt cccggaccag gcggcgctga
    15301 acacgtggat gcgcgaccac atgggccacg cggtggcccg cgccaccgac ccccgtcaca
    15361 gcgcacacgc cgcggtcctg cacggactcc tgaccgtgag cgaggtgctc gaacaggcgg
    15421 cgcccacccc ggcgaccgcg cgcacggccg cggtcctgtc gcgcttcgcc gcctacctgg
    15481 ggtccggtcc tcccccacac cgcttggagc aactccaagc cctgacgcgc gcaggcctgc
    15541 tccacttcct gggagcaggg ctgcgcgtca cccgcaccga cgccttcacc gcgcacacgg
    15601 actccctgcc gttcgcggtc agcgcgaggc acttcgtcga ggcccgcctg cccgaccccg
    15661 acgcccgcac gcacccgttg ctcctcccgc tggcgcacaa caggacccgc gtgccggtgg
    15721 acccggacac gttccacgtc ctcgacgaca cgggcgacgc acatccgcgc cgcctggcgc
    15781 tgggcctctt cgccggcgga ggggcactgg gcgcgttctc ccgtcccgga cgcaacgccc
    15841 cgttcttccg ccagaacgac gacacggccc gccgcgtcct cgccgaactg aacgccagga
    15901 ccccggcgct cacgccctga gctagtggtg cgtcccagaa ggtcggcgag gtaatccaca
    15961 ctcagcaggg cgcctcgcgg caccgccccc acgcccccgt actaccagta cgaggacgtg
    16021 ggggcggcac cacgatgcac ccgtctgacc gcgaattccc ccggcaacct tctgcgccac
    16081 accactagcc gacccgcggg ccggagtccg tgacgacggc acctctgctg aggtgcccgg
    16141 tgacggatcc cgtgttcgcg gggctcggcg ggcgctgttc cggcagcccg cgtggagctg
    16201 cggtggccat ggcccgagac atccgccgaa ggccgtccga acgcaccgcc accacggccc
    16261 gcggcacagc gcaaggcggg accggtcgga accggccccg ccttggtgat cacctcgtgg
    16321 tcacgccttc acggagtgct tcccgtgggt ccaggacgcg gcgtcgccgc cgtcgcccgc
    16381 cggaccggag tggccaccgg tcgtggtgct gtggttggag gcgtcgccgg tcgaacccgt
    16441 ggcaccggtg tcaccggagt cgcccgaggt gacctcggtc caggactgcg tgccgtggtt
    16501 cttccagccg tcgtgcttcc acccgtcgtg cttccacccg tcgtgcttcc agctgtgctt
    16561 cttccagctg tcgtgcttcc agccgttgtt cttgttctcg ttcttcacca ccgccgagtt
    16621 gccgccggtg tcaccggagt tcccggagtc gcccgagtca ccggtcgtgg cgttgttcga
    16681 gctcgtggcg ttgccgccct tgcccgagtc accgccgttg cccgcggtgg cctcagtgga
    16741 gccgttgtcg ctgtgcttgc tccacttgcc gtggtgcttc caggacttgc cctgctcggt
    16801 caccgcccag gcgtcaccgc cgtcaccggc cggaccggag ttcccgccca ccgtggtgct
    16861 gtggttccac gcgtcaccgg tcgagccggt ggcacccgtg tcgccggagt cgcccgacgt
    16921 gacggtcgtc caggacttgt cgccgtccca ggacttctcg tcccggttcc agccgtggcc
    16981 ctgctccgaa ccggtcgtgc gcacgacggc cttgttgccg ccggtgtcac ccgagctacc
    17041 ggagtcgccc gagtcaccgg tcgtggcgtt gttcgagctc gtggcgttgc cgccgttgcc
    17101 cgagttgccg ccgttgcccg cagtggcctc agtggagccg ttgttgttgt ggccccactt
    17161 ctggtccttg ctcacggccg tcgcgtcgcc gccgtcaccg gcggaaccgg agttcccacc
    17221 cacggtggtg ctgtggttgg aagcgtcacc ggtcgccccc gtcgcgcccg tgtccccgga
    17281 gtcacccgag ctcacgttcg tgtggcactc agcgagcacg cagacgccgt aggcgctgtt
    17341 gccgccggtg tcacccgagt tgcccgagtc accggagttc ccggacgtgg cgttgttcga
    17401 gctggaggcg ttgccgccgt cgcccgagtt gccgccgttg cccgcgttcg cgccggaatc
    17461 gcccgagcgg cccgccgcgg tggcgtcgcc gccgtcgccg gcggaaccgg agttcccacc
    17521 cgcggtggcg ctgtggttgg aggcgtcacc ggtcgatccg gtcgcgcccg tgtccccgga
    17581 gtcacccgag ctcacgttcg tgtggcactc ggccagcacg cacaggccgt aggcgctgtt
    17641 gccgccggtg gaaccggagt tccccgagtc gcccgagtcg ccggacctgg cgttgttcga
    17701 gctcgtggcg tcgccgccct tgcccgagtc accgccgttg ccgccgttga cgatcgagtg
    17761 cacggcgtcg ccgacgccgc ccaggaggcc gtcgccaccc gtgtcggcgc ttgccatcgc
    17821 cgttccgaac aggaggaagc ctcccgagaa cgctgcggcc accagaccgc gtcgcacaga
    17881 gctgtgcatt gtcgaacctt cctgttgatc aagcttggtg atctgccggc ttggtcgtca
    17941 ggactgctca actgggatgg ttccggccgt agtagtagca ccacgacccg tggacctggt
    18001 ggtcggtgac caccacgagg gacccgtcgc ccgcgtgaac tccccgttcc gccgggaggt
    18061 ccgagagcgc gaggcccgtc gatccggtcg aggacgccga tcccgtggtg ccggtcggag
    18121 cgaacggcac gccaggtgac ggcggggaag gcgcctcggt cggcggcgcc gcttcaggcg
    18181 cggagatcgg ttgccgctgc ggcgttcccg ccaccgcgac ctgttcgggc agagccacca
    18241 cgtgtgtctg tggcacgacc accggaacgt ccggtgtctc cggtgccacg gacaccggcg
    18301 gcgggacctc cgccgcggcg gagggctgtg ccaccagcgg ttccgcgatc cgcgggacca
    18361 gcggcacgtc ccgcaccgcg ttcaccacgg gggtgagcag cggcgcggtc acgggccgca
    18421 ggggctcgag caccgggtcc agcgcccgcg tcgccgtgtc gacgaccggc gcgagcggtt
    18481 ccagcaccgg ttcggtcacc ggctcggcgg cctccagcac cggttcgagc accggctcgg
    18541 ccaccgccgt cacgtccctc gtcagcggcg cgaccgaatc ggtcaccggc gcgacgagtc
    18601 cggcgacacc gcccagcgga ccgggcgacc cgccgtcgtc agcactcgcg acccccgccg
    18661 agagaaggcc gaatccgatg aggaaaccgg ccacgccgaa agtccgcttg agcgctgtgg
    18721 agcatgtcaa cttcatgcaa tcaccccctc tcaccgaatg agcacctgta cgtcaaggca
    18781 ttcgggttcc cccaagaggg tggattgcac aaaagtgcga gaaatttgtt ctccgcaggt
    18841 cacgagaact aattattttg aaacattcat ttccgactac tttgtgatga agagtcgcgc
    18901 gtccgatgtc gacggacggt gatcacgtgg tggaggcgcc gcgtccctgt gcgtccacag
    18961 gtgtgaacgc acagggaccc gcgtggcgcc gtcccgagcc ggctgaaccg catctggcgg
    19021 atcctcgcgc accacatccg taccccgcag cggttccgga tcggtgttcg aggcccattg
    19081 cacctgatcg agtgatcacc ggggtgcggg aagtgagacg tcctccaaag cgcgttcgag
    19141 ctcgcgccgg ttccgcgcgc cgagtttgtt gcggatgcgc gtgacgtggt gttccacggt
    19201 cttcgcggag atgaagagcg cgtcgccgac ctcgcggtag gtgagcccgt cccgcaccag
    19261 cgcggcgacc tcctgctcgc ggtcgctcag gacctccgcg cccccgttgc cctggccgcc
    19321 gttcgtgccg tggaactggc gggcgatgtc gagcagctgc gtcatggccc tgcggtcggt
    19381 ggtgtgcatc gccgcgtgcc cggcgagccg tgccgcgtcg gcgcgcaggc cgtgggcgtg
    19441 cagttcccgc gccgccgact cgacgcgcag gtggtccacg tcgccgtgac cggcctcgct
    19501 ccagcagtgc gcggcggtcg cgagcgcgcg gccgaacggc aacgcgtccg ccgcggtgtc
    19561 cagcgccgcg aggtgctcct cggcagcggg gtggtccccg aggagaagtg ccgcgtggaa
    19621 ggcgttccag cgcggcagca ccgtccacag gggagggtcg cccaggtcgc cgagcaacgt
    19681 ccacgcctcg tccaggtgcg tctcgacccg gtggaactgc ccgatcctgg ccgccgcgac
    19741 ggcgatctcg gtcagcggga gcagcgtgta gaggtcgacg gggtgcacga cgagcgcctg
    19801 ctgggccggt tcccacgccg cgcgcagggc gtggaggtcc ccggcgcggc gggtgacgcc
    19861 gagctccagc gccgccgcga acagggcctc ccgcggctcc cgggagaggt cgggacgcga
    19921 aagtcgtcgt gcctcttcga cgtcaccgcg gaacaggtcc acgcaggcga gcagcagctg
    19981 gtgccggtcc gcgtgcagtc cccggccgtc gtcgccccgc accgccttgg ccagcaacga
    20041 cctcgccacc gacagctctc ccgcgtggac gcagaccaac gcggcgagtg cggtgggact
    20101 gtccggttgc accgacgccc tggagcccgc ctggttcacc cccgccgtgg ccaccgcggc
    20161 ggcgacggcg gccatcggcg ggccggtgac cgtgtcgagg acgacgcccg ccagccggtg
    20221 cccgagcgtg tcggtgagcg acgctgcggg gtgcgcgccg gactggacgg cacgcgcctc
    20281 ctccagccgt ccggcaccga ggagaccggt cacggcgaag cccagcgcga ggccgttgtc
    20341 cgagcgccgg agcagttcgc ccccgcggcc gacctgcccg cgcagcgtca gcacggtcgc
    20401 ggcgaccagc agcgcgtccg cgtcggcgtg ttcgaggtcc accacgtcca cggccccgtc
    20461 gaggtcgccg ctgagcgcgc gggcccgcgc gaggagtgcg gaggagcccg gaccggcggc
    20521 ggcgaacacc cgcgccgcga gcgccgggtc gtcgtcgacc acctcgtgtc ccgccgcgat
    20581 gaacacgtcc gcgagcccgg ggtccacgac gccgagttcc agcagcggcc gcgcgtaccc
    20641 ggccaccggc tgcgaccgtt ccacctgggt cagggcgagc ctgcgcagca ggtccgcgcg
    20701 ctgttccgcc ggagcgagcg cctcggccgc ctcggcggcg acgggcagcg gtgccccgtc
    20761 gatccggagc aggccggccg atctgagggc ctcggcggac tccgacacca cgtgggggtc
    20821 cagcgcgagg accgccgcga gcagttccac gtcgaacggg gcgccgagcg cacgggccag
    20881 cagcaggtcg ttcgccgcga cgggcagttc gtcgaggtgg cgggcgaacg cgccgcgcgg
    20941 ctcgggcgac agctcgtcca gcacgaaccc cggcgtgccc ccggtccgct cgtgcagccg
    21001 tcccgcgacc tcgtcgctca cctcggcgcc gagaacgcgc gcggcgagcg accggacctg
    21061 cccctgcgtc agcggccgga gccgcacgcg gaccacggtc cccggcaacg cgccgaccag
    21121 tcgccccagc gcgcggttgt ccggccacgg ccgatgcgcg agcacgagcc ggccgcccgc
    21181 acggacctcg tccagcagcc ggtcggcctc gtcctccccg agcgcgtgcc cgtcgtcgac
    21241 ggcgatcggc tgtgcgaagg cgcgcagcaa cgtggtcttg ccgcacccgg cgggcccggt
    21301 cagcacgacg tggtccgcgc cgcgcgcccg ttcgagcgtc cgggccgtcc cgtcgtcgag
    21361 caacaagggc gtgtccggca tcggggacat gagcgcgtga acctcctggt ggccgacctc
    21421 taccggggta cttcggttca tcacccgttc aggcttggtc tcgaccggaa gatcgggaaa
    21481 caccccctat ccccctacac gcggtagccc caacccccga tccgtccccc acctacagga
    21541 ccaggcacgt cacccgatgc ggtgatcaac ccgctcttcg tagctttcag tggcacaagc
    21601 acaacgacgc acctggagtt cgacgtgacc ctgccgcaga cgctgcacga cttcaccctc
    21661 aacctgctga gcgacccgga ggcccgctcg gccttccagc tcgacccgca gggctcgctc
    21721 gacgcggccg gcctcggtga cgtgcacccg gcggacatcc aggagctcct gccgctcgtg
    21781 ctcgacttcg ccccggtcac ctcgctcggc gacttcggct cgacgatctc cggcctcgac
    21841 ctcgaccagc agctcgacct catgagcacg ctgcagaaca ccgtcggcca gcagctcgac
    21901 gacaacacgg tcctcggcgc cgtctcgggc ctcaccgccg ccgtgcacgg cgtcaccaac
    21961 ggcttcgacg tgctcagcga cccgtcgagc gccctggacg tcgtcgccgg gaccgagatc
    22021 accgacgtca ccaagaccgt caccgacctc gacgtcacca acaccgtcgg cgacatcacg
    22081 aacggcaccg acgtcctcga caccacgcac gtcaccgacg tcgtcggcga cgtcacgagc
    22141 ggcgtgcaga ccggcgacct gggcgtgaac gacgtgctca gcggcgacgt cacctccgcc
    22201 atcggcaccg tgacgggcaa cgacctctcc ctcgaccacg tcggcaacgt caccgacgtc
    22261 gtctcgcacg tgggcaacgt cggcgacgtg accggcgtcg gctccgtcgg cgacctcggc
    22321 aagatcggcg acatctccgg cgagctgggc gacgtcaacg tcggcggcgt cctgaacgac
    22381 ctcgacctga gcctctgacc cacccgcacg tgcaggccgc cccgaccgcg ccccggggcg
    22441 gccttgcggc gttcgccagg tcttcggagc cgcaatcccc accggtcgcg gctccgaaga
    22501 cctggtgtga aacaaggaga caccgccccc gactt
//
