LOCUS       NZ_CP099738            21074 bp    DNA     circular CON 27-AUG-2024
DEFINITION  Lentzea sp. HUAS12 chromosome.
ACCESSION   NZ_CP099738
VERSION     NZ_CP099738.1
KEYWORDS    RefSeq.
SOURCE      Lentzea sp. HUAS12
  ORGANISM  Lentzea sp. HUAS12
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 9676923)
  AUTHORS   Ping,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JUN-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024125735.1-RS_2024_08_27
            Annotation Date                   :: 08/27/2024 06:34:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,161
            CDSs (total)                      :: 9,080
            Genes (coding)                    :: 8,988
            CDSs (with protein)               :: 8,988
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 21 of 92
            Pseudo Genes (incomplete)         :: 77 of 92
            Pseudo Genes (internal stop)      :: 3 of 92
            Pseudo Genes (multiple problems)  :: 8 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:47:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4341983
            Orig. end                         :: 4363057
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP099738.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Ping Mo.
FEATURES             Location/Qualifiers
     region          1..21074
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="20"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..21074
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21074
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11074](+)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11074
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     gene            29..1477
                     /locus_tag="ND450_RS19195"
                     /old_locus_tag="ND450_19195"
     CDS             29..1477
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229155.1"
                     /locus_tag="ND450_RS19195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19195"
                     /product="oligosaccharide flippase family protein"
                     /protein_id="WP_253327437.1"
                     /sec_met_domain="Polysacc_synt (E-value: 1.3e-16, bitscore:
                     60.0, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGARGVRGAARPARRMTDVAVRGSLWLFAVNLVSKSSQIVVTLA
                     LALFLTEADLGAVALVVSIVNIGQVVQAMGVYDIVSRTTRDPLTTAGTVLTMSVAAGAV
                     LAAVLVATAGPLAAALGAPDAAGMLRLAALTLPFTAAGGVQMALMHRDLDFRRRMLPDA
                     GGMLLGAAVTVTLAAQGTGPSALVWGLLCTAVAQPVLAAVAGARIRPVWDRDAAAEATR
                     WLVVVGPGALIAVLLINVDYLAIGHVLGPQAVGGYSLAFRIAWVPYIMIAVVLGGVLFP
                     ICAELVRSGRSDQLPNTLGRFTTATLVITGGLYTTVALSAHGIVVLGEQWAGAARLLAL
                     LCGYGFGLGLLHVWYQVIRAAGHARQYLALEATHLVLLLTALVFTTGHGPAAVAITQVT
                     VVWLLVPVTWLVLRRNGLAFPFPVRAISSVGGAAAACWAISVLLPGSTGLAGLVTTGLV
                     LLTAYCAITLPLNRTVLIGLKERA"
     gene            1474..2541
                     /locus_tag="ND450_RS19200"
                     /old_locus_tag="ND450_19200"
     CDS             1474..2541
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229156.1"
                     /locus_tag="ND450_RS19200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19200"
                     /product="glycosyltransferase"
                     /protein_id="WP_253327438.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 9.3e-36,
                     bitscore: 122.1, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIVHVTQPVEAGVAVVVLALARAQRERGWDVSIACPDTGWLPER
                     AHKAGIPLLPWQATRSPGPRTALELRALRKILRRLNPDVVHLHSSKAGLARLVVRNGVP
                     TIFQPHLWSFRVATGVLSRACRFWEAQASRWTSLLLCVSDDELKAGREAEVTARAEVVC
                     NGVDTGRLTPRAKTNDTPTAVCVGRLAHQKGQDLLLEAWPHVLGKVPDAELLIVGDGPM
                     AAQLQARHHPHVRWHGHSDAVHTHYAEADVVVLPSRAEGMALVPLEAMACGRPVVAFDV
                     EGVAQSIGDAGEVVPPGDVKALAQAVALRLADPELAAAEGKRGRQRAETLFDRDRMTDQ
                     IVTLTARLVTEEGRR"
     gene            2538..3635
                     /locus_tag="ND450_RS19205"
                     /old_locus_tag="ND450_19205"
     CDS             2538..3635
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229157.1"
                     /locus_tag="ND450_RS19205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19205"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_253327439.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 6e-27, bitscore:
                     93.4, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRIAYLLTQDSGGPVDVTVRLAAALAESGEAEVRVFGPRPRRGA
                     ELIDPFFEETLVVRKGDMAAARQARAAIKAWRPDLVHAQDRRSGLVSAPLATTGTKIVH
                     TYHGVPDDVAEPWFRNVRGATPPPAYTRAVLAADAAVARVVHRTVVPAREMGRFLRERL
                     YVPPHRMTHIDNCVEVGAANPPARPVRKLIFVGLLVERKGLLDLLDALETTMPRDATLT
                     IVGDGPQRSQAEGRVTRRGLGDRVRFLGFRGDVPELLLGHDALVLPSTMEQQPLVVAEA
                     MAAGKPVVATDTGGVADMLGIPGDDCPKPGDVPALAARLKELFADPDPASTGDRLATRA
                     RERFTPEVCARRHLDLYRRLTAADR"
     gene            complement(3616..4851)
                     /locus_tag="ND450_RS19210"
                     /old_locus_tag="ND450_19210"
     CDS             complement(3616..4851)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640649.1"
                     /locus_tag="ND450_RS19210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19210"
                     /product="putative glycoside hydrolase family 15 protein"
                     /protein_id="WP_371927731.1"
                     /transl_table=11
                     /translation="MLSEKSLIRRFAVVALVLLSSACAVSAAESDPIITGPIPKALAPC
                     AWWYGIGDSPSAWEIRAAAKHYDVVVLNAWETAAMRKLHELNPKVKVLVYKDFSSTRNY
                     NGAVEGDRDAQYLPTGIGYNAAERTPGWFAISTLGQRIEWDGYPKHWQMTVWDPAYQKA
                     WADAVVSEVLREGWDGVLADNDFSSLKYYSPSVIAGTADAAGSDRLLRDGLDGMLELTG
                     DALEKAGKMLVPNVSESQLTPGRWSAHSRYAGAMEENFGLRGDDGTGELITFQGNQFKE
                     QRAQAALGESWLLLITHTKSDREERVGYASAALLASPHTCWTRAQPDYKNPYWSTYQDA
                     RLGEAVETANRLPSGVWNRRYSNGWVAVNPTKTSVLLTPPPGLVTLRGEPVPPQLDLPA
                     ADAVVLVNGPRR"
     gene            complement(4830..6272)
                     /locus_tag="ND450_RS19215"
                     /old_locus_tag="ND450_19215"
     CDS             complement(4830..6272)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146: sugar transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229159.1"
                     /locus_tag="ND450_RS19215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19215"
                     /product="sugar transferase"
                     /protein_id="WP_253327441.1"
                     /sec_met_domain="Bac_transf (E-value: 3.2e-61, bitscore:
                     205.0, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRFSAVAVPADPLLTHEAELLRPAQRPLKPSSVGRDVLSRVNAV
                     AVLLAFADLAALAVVCVRHGLGWGWSTAVVASVVTIRGTWRLYRRRLWLSWLQDLPRSA
                     ASTALAFALLSGAGLVGGSDQAALSGAQWAMIEFALVIEPVRWAVFAFGRWCRRRFDRC
                     DRTIIVGAGEVGVNLAKTMLEHPQFGLRPVAFADSGPDPDRRPPLLEVVEGDLADAIVR
                     LKAGTVVLAFSHTRDSPLVEAAITAHRLGCSTLVVPRMYELHPDGPGIERLRSYPLMRL
                     GTAPTSRPTWWIKRAADLVLAAFALVVLSPVIGLCALAVLVESGRPLFFRQVRVGMDDR
                     TFTLYKIRSVRQTGEDDSQSTWSVVGDSRVGPVGRFLRRTSLDELPQLWNVLRGDMCVV
                     GPRPERPGFVREFSAIHELYWARHRVPTGLTGLAQVHGLRGDTSIADRSRYDNYYIANW
                     SLWLDLRILLMTAGELCCRRNR"
     gene            6510..7334
                     /locus_tag="ND450_RS19220"
                     /old_locus_tag="ND450_19220"
     CDS             6510..7334
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103321.1"
                     /locus_tag="ND450_RS19220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19220"
                     /product="glycosyltransferase"
                     /protein_id="WP_253327442.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.9e-24,
                     bitscore: 83.5, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVDEHGIRHSAGEPVAIVQKPISTCGDVHVVLPAYNEAVALPSL
                     LARIAGTDLAPRITVWVVDDGSSDGTGACTADVRGLDVRLVTHPVNLGLGQAVQSGLMA
                     ALAEAAPDDVLIVMDADDTHDPGVFPAMLAEVKAGADVVICSRFVAGGDDSTAPQWRRL
                     LSRGARVVFGKVLHFDGVQDFTSGFRAYRVSLLRRAAAHWGERLVEERGFACMVELLLK
                     LRHCGPIVSEIPLHLRYDRKPGASKLRLGRTLKQYLLLLTRDRLAPVPFRKL"
     gene            7334..8668
                     /locus_tag="ND450_RS19225"
                     /old_locus_tag="ND450_19225"
     CDS             7334..8668
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103322.1"
                     /locus_tag="ND450_RS19225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19225"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_253327443.1"
                     /sec_met_domain="DAO (E-value: 1.5e-09, bitscore: 37.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQRVVVVGGGICGLATAHRLAREGLAVTLLEASDQLGGLGTFFT
                     SQGRSVERFYHCVMPTDAALLALLDEVGLRESVQWNPTTMGMVVEGEHRSFNSALDLLG
                     FRPLSFADRIRFGVVSVLLRRLGKGKDLDNLRTEDWLRGLYGDRIWELLLAPLFGAKFG
                     SAFGDVPALYVWQRLGRESNESVRGYPAGGYKSVIDALQASIEAHGGEVRTSAPVGRLE
                     ASQDRVLVTLIDGETIEADHAVSTVPLPALRSIADPDLAPRLPEVRLPYQGVVNALFFL
                     RKPLSGHYWAPVIRSGTDFDGVIEMTPLTGSERYGDRHLVYVMHYTDRESALYREDSDS
                     IARRWTEQLLSIHEGLTPDDVDEVRVFKAPFVEPVYPLGYLAQRPPVEVPGTRLRLATT
                     AHVYPNVTSWNSSVELSNSVTDALLRDARSSSTQEDTAWSAESAR"
     gene            8644..9600
                     /locus_tag="ND450_RS19230"
                     /old_locus_tag="ND450_19230"
     CDS             8644..9600
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016641 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013674135.1"
                     /locus_tag="ND450_RS19230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19230"
                     /product="lysyl oxidase family protein"
                     /protein_id="WP_253327444.1"
                     /transl_table=11
                     /translation="MVSRIGAVIAALTITAVNLVSSQHVQADPAPLLPDLRQAPIGCPG
                     GHDGAPLLCRAWDVCLVEDASAPRGKCMNRGGRAQAVRLRFTTSIDNVGDGPLLLHAHR
                     DSTATPTMRVRQAVQSGVDGSIAGSYNEAGRETSSSAYYEPAPTHTHWHLLNFEYFQLR
                     TPDGGVVVTDRKNGFCIGDRYTVSDDLEHRPSDPESPEGKLAQRLRGHMCEHHNPSALD
                     VMFGISVGSGDDYKYEVDFQWLDLTNVKSGTYDVVNVVNADRALLEKNYDNNAASIAIS
                     VQWPGGAVNPPATIDEAPSVRMIRSCPGKARCAKSRG"
     gene            10001..11074
                     /locus_tag="ND450_RS19235"
                     /old_locus_tag="ND450_19235"
     CDS             10001..11074
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF023417.5"
                     /locus_tag="ND450_RS19235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19235"
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_305885229.1"
                     /sec_met_domain="indole_PTase (E-value: 3.7e-94, bitscore:
                     314.7, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDFAIGQLHDLLRAVGLTNSAESATELLGEALGPGSRLPLSAVP
                     HWPSSVADDHTPVEFSVALAQNEPPAVRMIVESLAEQPGRQANVTAALRVLDGLTERHQ
                     VRLRQLDLVRDLFLPEDPQGAFAFWYSLIVGPGAPPAVKVYLNPDVRGRESATALVGEA
                     LSRLGLSAALPAVQEHALRRAGLDRFSFFALDLMEEDRARVKTYVAHDDAVVADVVRAA
                     AAVPAVDPAILADVCELACGGTGPFSRRPLMSSYTFLSGDTERPSGYSLYIPVRDYVQD
                     DLEACERVLAIMARCGLDTTPFVMALASLVQRPLGDGVGLIAHVSLRLGRPKPGVSVYL
                     SSEAYDVTPPRTKALSA"
     misc_feature    10052..10054
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    10097..10099
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11099..12460
                     /locus_tag="ND450_RS19240"
                     /old_locus_tag="ND450_19240"
     CDS             11099..12460
                     /NRPS_PKS="Domain: Beta_elim_lyase (41-417). E-value:
                     5.3e-72. Score: 234.4. Matches aSDomain:
                     nrpspksdomains_ND450_RS19240_Beta_elim_lyase.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686627.1"
                     /locus_tag="ND450_RS19240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19240"
                     /product="tryptophanase"
                     /protein_id="WP_253327445.1"
                     /transl_table=11
                     /translation="MEPYRIKVVEPIPITTREHRERRYSEAGYNQFNLTAEDVTIDLLS
                     DSGTGALSAEQQAAGMRGDETYAGSRSWFRFREVASDLTGYEHILPVHQGRAAERILFS
                     ALLKPGQISVSNTHFDTTRANVELAGGVVRDLPSPAFSDFDSDVPFKGDIDLVALEALL
                     DGPEDVGLVLITITNNGGGGQPVSMANLEAVRALCGKHGVPFILDAARFAENAWLVTQR
                     EERYRGHSPREVAKLAFRLADGCVLSLKKDGIVHIGGMLALQDADLAKQCELLLIATEG
                     FSTYGGLSGRDLDMCAQGLVEVTDPMYLRERADATAYLADCAREAGVDSVRPTGVHAVY
                     LNAARLLPHIPPSRFTGHALASELYLAGGIRCAEVGSLYLGDIDPSGELLTPAPFELVR
                     LAIPRRVYTRSHLEYVAETLAGIARDPEQVPGYRLTEVPPILRPFRCRLEQIRP"
     misc_feature    11114..11128
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     aSDomain        11222..12349
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ND450_RS19240_Beta_elim_lyase.1"
                     /evalue="5.30E-72"
                     /label="ND450_RS19240_Beta_elim_lyase.1"
                     /locus_tag="ND450_RS19240"
                     /protein_end="417"
                     /protein_start="41"
                     /score="234.4"
                     /tool="antismash"
                     /translation="DLLSDSGTGALSAEQQAAGMRGDETYAGSRSWFRFREVASDLTGY
                     EHILPVHQGRAAERILFSALLKPGQISVSNTHFDTTRANVELAGGVVRDLPSPAFSDFD
                     SDVPFKGDIDLVALEALLDGPEDVGLVLITITNNGGGGQPVSMANLEAVRALCGKHGVP
                     FILDAARFAENAWLVTQREERYRGHSPREVAKLAFRLADGCVLSLKKDGIVHIGGMLAL
                     QDADLAKQCELLLIATEGFSTYGGLSGRDLDMCAQGLVEVTDPMYLRERADATAYLADC
                     AREAGVDSVRPTGVHAVYLNAARLLPHIPPSRFTGHALASELYLAGGIRCAEVGSLYLG
                     DIDPSGELLTPAPFELVRLAIPRRVYTRSHLEYVAE"
     gene            complement(12514..13107)
                     /locus_tag="ND450_RS19245"
                     /old_locus_tag="ND450_19245"
     CDS             complement(12514..13107)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100435.1"
                     /locus_tag="ND450_RS19245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19245"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_089919432.1"
                     /transl_table=11
                     /translation="MVSVQSEQGREELSVPTSVKIVVAGGFGVGKTTMVGAVSEITPLR
                     TEELLTEAGEEIDDLYGVEGKTTTTVALDFGRITINPELVLYLFGTPGQDRFWFLWDEL
                     AIGSIGAVVLVDTRRLDAGFGAIDFFERRGIPFVVAVNCFQGSHTYTTEELRVALDVPD
                     SVPLVLCDARDRESCKAVLVRVIEHAMNRLDVMA"
     gene            complement(13088..13465)
                     /locus_tag="ND450_RS19250"
                     /old_locus_tag="ND450_19250"
     CDS             complement(13088..13465)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942553.1"
                     /locus_tag="ND450_RS19250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19250"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_089919434.1"
                     /transl_table=11
                     /translation="MSNSSDWWYDEAAGPMVRPYAMVSGRTRPKPAGEDLTLTTQVRAL
                     RTTTDQGTLSVEHLEIIKLCRKPLSVAEVAAYLHAPLVVVKVLLSDLIQRGDVITSSPS
                     TKVVPVDMNLLQKVLDGVRAI"
     gene            complement(13462..13899)
                     /locus_tag="ND450_RS19255"
                     /old_locus_tag="ND450_19255"
     CDS             complement(13462..13899)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229428.1"
                     /locus_tag="ND450_RS19255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19255"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_253327446.1"
                     /transl_table=11
                     /translation="MDDLTSGHPELNWLLEDLVARVVGARHAVVLSADGLLLAHSPELS
                     KDDSDHLSAMASAFQSLARGTGRHFGGGQVRQTIVEMERAHLFVTAAGQGACLAVVGDE
                     DADMGMIAYEMNMLVKRVGAYLSSAPRTMASPRMPNPLGLS"
     gene            complement(13926..16319)
                     /locus_tag="ND450_RS19260"
                     /old_locus_tag="ND450_19260"
     CDS             complement(13926..16319)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100432.1"
                     /locus_tag="ND450_RS19260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19260"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_253327447.1"
                     /transl_table=11
                     /translation="MVVPSVVLLAMWALFSSYTVFEGLYLQLVASGARDASIPAVQSFA
                     SLQKERELSMTSLSRSGATSSALLKQQQDTDKDVEKMKAAFGELASQAPQEIVDGINKL
                     NGLLDQLPDQRERLESGNSSKDEVYRYYNSVLDAGGSLFGTQARIVPDAETVQGALTAL
                     QAFQASDAMSRASSVAAGAIAAGKFTPEEHREYVNLVGAYHFTLNVIEPVALPDVREHY
                     KQLTGSAPYQQLVTFENRLLQNSERPVGQQVTLADFENATRAVSQEIVTMVQEQSTGAV
                     NIAMANGKEKFTTVLIGSLIALIAVIAGIFVAVRVSNRLVNKALIVRLISLKSDSLKLA
                     HERLPDIVERLRDGKHVDVAAEVPALDYGNDEIGQVADAFNAAQYTAVAAAVKESQTRE
                     GVNRVFLDIARRNQGLVHRQLKILDKLEREEENPDHLDAFFQLDHLATRARRNAENLII
                     LTGEQPGRQWRKPVRMLDVVRAAVAETEQYARVKVNPVPEVALVGAAVADTIHLIAELV
                     DNATSFSSPRSQVEIHSSEVPQGLVIEIEDHGLGIKPEDREQHNQMLEAPPDFEAMRLR
                     GESRLGLFVVARLAARRHIHVELRDCPSGGTIALVLIPSELIVGEAGAVDPADSVQMPK
                     PTFRQQTMQQAARSPEALEAAVPLQGDLTHESLPAERPTETFQLDEFWAGRAVGNGHAP
                     DPERDLDSNSGQLELPRDDRQAGAWPTDDPAEGETTRQNARPELPRRRRQQHLVPQLAN
                     DDLRPMPELAEFNPEERAERTRDGMAAFQRGTRDARQADDVVEP"
     misc_feature    16341..16355
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.69"
                     /tool="antismash"
     misc_feature    complement(16440..16454)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.86"
                     /tool="antismash"
     gene            complement(17107..18093)
                     /locus_tag="ND450_RS19265"
                     /old_locus_tag="ND450_19265"
     CDS             complement(17107..18093)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS19265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_19265"
                     /product="hypothetical protein"
                     /protein_id="WP_253327448.1"
                     /transl_table=11
                     /translation="MSRNRSGCGGCALAFLALFFWLPLALVLVSPAIALRTAVDGVPEQ
                     VFHPREWLWGAAFSVPLSVLVVRSVFRRDGRVRGAPPGKRWAGLLAHGLVLLAATNLVA
                     YQKNAPGEYVVQNSDLPFVGTASLTAVAVLVVMALWDRRARRVTVEEVREAAAQADRAL
                     KRVHAENAKVHRQAEQVQARLVKLQARAPVRNRRGEVEFHSLRVFHRESYQCADTAHLA
                     YTSAQTSLRTMSPLVRRARSAALQLTVSRRARAEMRAAATHLATSCGELRAQVDHGLGM
                     VRDLNANTSELKHEIRDNCGAQGRRWFEELEERIEQAREERRTSRTR"
     gene            complement(18090..18581)
                     /locus_tag="ND450_RS19270"
                     /old_locus_tag="ND450_19270"
     CDS             complement(18090..18581)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS19270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_19270"
                     /product="hypothetical protein"
                     /protein_id="WP_253327449.1"
                     /transl_table=11
                     /translation="MGLVTVNGKDVGFTDALSRVAEQLEPLGDAGRCVAETYALATEIR
                     RITEAAAVDDREVKLAVLHQRRRESTASLRSMRKELGRADRSAAALRECMVNMQRATVK
                     PGIELAERRAYIDLTQHFTTMLVQHHTELTGGVADVIDKVLNGSGATALAPARKPRRRR
                     "
     gene            complement(18636..19661)
                     /locus_tag="ND450_RS19275"
                     /old_locus_tag="ND450_19275"
     CDS             complement(18636..19661)
                     /NRPS_PKS="Domain: PKS_ER (13-263). E-value: 8.1e-12.
                     Score: 36.8. Matches aSDomain:
                     nrpspksdomains_ND450_RS19275_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020422704.1"
                     /locus_tag="ND450_RS19275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19275"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_089919442.1"
                     /sec_met_domain="ADH_N (E-value: 6.3e-33, bitscore: 112.0,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.3e-20, bitscore:
                     71.5, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAVQVVGYHQPLALTEVEQPKATGPFDVVVRIGGAGVCRTDLHI
                     LEGQWAEKSGVALPYTIGHENAGWVHEVGSAVTNVAVGDKVIVHPLITCGLCRACRSGD
                     DVHCAASQFPGIDTAGGYAEYLKTSARSVVKIDDALEPSDVAALADAGLTAYHAAAKAA
                     RRLRPGDRCVVIGAGGLGHIGVQVLKALTAAEIVVVDRNPDAVKLAETIGADHGVVADG
                     SHVSAVLDLTGGNGAETVIDFVGEGGATKDGVAMLRRAGDYHVVGYGENIDVPTIDIIS
                     TEINLIGNLVGSYNDLCELMVLAAQGKVTLHTQKYPLDRFQDAIDDLDAGRVRGRAILT
                     P"
     aSDomain        complement(18873..19622)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ND450_RS19275_PKS_ER.1"
                     /evalue="8.10E-12"
                     /label="ND450_RS19275_PKS_ER.1"
                     /locus_tag="ND450_RS19275"
                     /protein_end="263"
                     /protein_start="13"
                     /score="36.8"
                     /tool="antismash"
                     /translation="ALTEVEQPKATGPFDVVVRIGGAGVCRTDLHILEGQWAEKSGVAL
                     PYTIGHENAGWVHEVGSAVTNVAVGDKVIVHPLITCGLCRACRSGDDVHCAASQFPGID
                     TAGGYAEYLKTSARSVVKIDDALEPSDVAALADAGLTAYHAAAKAARRLRPGDRCVVIG
                     AGGLGHIGVQVLKALTAAEIVVVDRNPDAVKLAETIGADHGVVADGSHVSAVLDLTGGN
                     GAETVIDFVGEGGATKDGVAMLRRAGDY"
     gene            complement(19658..20314)
                     /locus_tag="ND450_RS19280"
                     /old_locus_tag="ND450_19280"
     CDS             complement(19658..20314)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659646.1"
                     /locus_tag="ND450_RS19280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_19280"
                     /product="iron-sulfur cluster assembly protein"
                     /protein_id="WP_253327450.1"
                     /transl_table=11
                     /translation="MIDTAVFQALDEVMDPELDEPITTLGFVRSVELDGDVLTVHLRLP
                     TAFCSPNFAYLMASDSKDVLRDLAPHVVVVLDDHHDSDVINRGIAADSGFVGTYGEEAS
                     RELEELRLTFQRKAHAAAMERAVRDVPVDRLRSLTLKDLPATKAAEALRRRRSALGFDT
                     SPDAPVLVDDHGVPLPAGQLPLRLRFARSVGISIEGNAHFCRGLLRTRYAMEESA"
     misc_feature    20730..20744
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
ORIGIN
        1 cgctggacgg ggtggcgctg gtggcggcgt ggctggtgct cgcggtgttc gcggtgcggc
       61 acgtccggcg cgccgcatga cggacgtggc ggtgcggggg tcgctgtggc tcttcgcggt
      121 caacctggtg agcaagagca gccagatcgt ggtgaccctc gcgctcgccc tgttcctcac
      181 cgaggccgat ctgggcgcgg tggccctggt cgtgtcgatc gtcaacatcg gccaggtcgt
      241 ccaggcgatg ggtgtctacg acatcgtcag ccgcacgacc cgcgatcccc tcaccacggc
      301 cggaacggtg ctcacgatga gcgtcgcggc gggcgcggtg ctcgccgcgg tgctcgtcgc
      361 caccgccggc ccgctcgccg ccgcgctcgg ggctccggac gcggccggga tgctgcggct
      421 cgcggcgctc accctgccgt tcaccgcggc gggcggggtg cagatggcgt tgatgcaccg
      481 ggacctcgac tttcggcgcc gcatgctccc cgacgcgggc ggcatgctcc tcggcgccgc
      541 ggtcaccgtc acgctggcag cgcagggaac cggcccctcg gcactcgtct ggggcctgct
      601 gtgcaccgcg gtcgcccagc ccgtgctggc cgccgtggcc ggagcgcgga tccgtccggt
      661 gtgggaccgc gacgccgcgg cggaggcgac ccgctggctg gtggtcgtgg ggccgggggc
      721 gttgatcgcg gtgctgctga tcaacgtcga ctacctcgcg atcgggcacg tgctcgggcc
      781 gcaggcggtg ggcggctaca gcctcgcctt ccgcatcgcc tgggtgccgt acatcatgat
      841 cgcggtcgtg ctgggcgggg tgctgttccc gatctgcgcc gaactcgtcc ggagtggacg
      901 gtccgaccag ctcccgaaca cgttggggcg cttcaccacc gcaacgctgg tgatcaccgg
      961 cggcctctac acgacggtcg cgttgtccgc ccacgggatc gtggtcctcg gcgagcagtg
     1021 ggccggcgcg gcacggctcc tcgccctcct ctgcggctac gggttcggtc tcggcctgct
     1081 gcacgtctgg taccaggtga tcagggccgc cggccacgcc cgccagtacc tcgccctcga
     1141 agccacccac ctcgtcctgc tgctgaccgc gctggtgttc accaccgggc acggcccggc
     1201 ggcggtcgcg atcacccagg tgaccgtcgt gtggctgctg gtcccggtga cctggctggt
     1261 gctccggcgc aacggcctcg cgttcccctt cccggtacgg gcgatctcga gcgtcggcgg
     1321 cgcggcggcg gcgtgctggg ccatcagcgt cctcctgccc ggcagcaccg gcctcgcggg
     1381 cctcgtcacc accgggctcg tgctgctcac cgcctactgc gcgatcaccc tccccctgaa
     1441 ccgcaccgtc ctcatcggac tgaaggagcg cgcgtgaaga tcgtccacgt gacgcagccg
     1501 gtcgaggccg gtgtcgccgt cgtggtcctg gccctcgcca gggcccagcg ggaacggggc
     1561 tgggacgtca gcatcgcctg cccggacacg ggatggctgc cggaacgagc tcacaaagcc
     1621 gggatcccac tgctcccctg gcaggcgacc cgcagccccg ggccccgcac cgcgctggaa
     1681 ctcagggccc tgcggaagat cctgcggcgg ctgaacccgg acgtcgtcca cctgcacagc
     1741 tcgaaagccg gtctggcgag gctcgtcgtg cgcaacggcg tccccacgat cttccagccg
     1801 cacctgtggt cgttccgcgt cgccaccgga gtgctgagca gggcctgccg gttctgggaa
     1861 gcgcaggcct cccgctggac gagcctgctc ctctgcgtca gcgacgacga gctgaaggcc
     1921 ggccgggaag ccgaggtcac cgcacgagcc gaggtcgtct gcaacggcgt cgacaccgga
     1981 aggctgaccc cgcgggccaa gacgaacgac acccccacgg cggtgtgcgt cggcaggctg
     2041 gcccaccaga agggccagga cctgctgctg gaagcctggc cccacgtgct cgggaaggtc
     2101 ccggacgccg aactgctgat cgtcggcgac ggtccgatgg cggcacaact gcaagcacgg
     2161 caccaccccc acgtgcgctg gcacggccac agcgacgccg tccacaccca ctacgccgag
     2221 gccgacgtcg tggtcctgcc gtcccgcgcc gagggcatgg cgctggtgcc gctggaagcc
     2281 atggcgtgcg ggcgcccggt cgtcgcgttc gacgtcgagg gagtcgcgca gagcatcggc
     2341 gacgcgggcg aagtggtgcc ccccggcgac gtgaaggcgt tggcgcaagc ggttgcgctg
     2401 aggctcgccg accccgaact cgccgcggcg gaggggaaac ggggccggca gagggccgag
     2461 accctgttcg accgcgaccg catgaccgac cagatcgtga cgctcaccgc gaggctcgtc
     2521 accgaggaag gacgacgatg acacggatcg cctacctgct cacccaggac agcggtggcc
     2581 cggtggacgt gacggtgcgc ctggccgccg cgctggccga gtcgggtgag gcggaggtgc
     2641 gcgtcttcgg cccgcggccg aggcgcggcg ccgagctgat cgacccgttc ttcgaagaga
     2701 ccctggtcgt gcgcaagggg gacatggccg ccgcgaggca ggcccgcgcg gccatcaagg
     2761 cgtggcgccc ggacctcgtg cacgcccagg accgccgctc aggactggtc agcgcgcctc
     2821 tcgccaccac cggcaccaag atcgtgcaca cctaccacgg cgtgccggac gacgtggccg
     2881 agccgtggtt ccgcaacgtc cgcggcgcca cccctccccc ggcctacacc agggcggtgc
     2941 tggccgccga cgccgccgtc gcccgcgtcg tgcaccgcac ggtcgtcccc gccagggaga
     3001 tgggcaggtt cctgcgcgaa cgcctctacg tgccaccgca ccgcatgacg cacatcgaca
     3061 actgcgtgga ggtcggcgcc gcgaacccgc ccgcccggcc ggtgcgcaaa ctgatcttcg
     3121 tgggcctgct cgtcgagcgc aaaggtctgc tggacctgct ggacgcgctc gagaccacaa
     3181 tgccgcggga cgcgacgctc acgatcgtcg gcgacggtcc acaaaggtct caggcggagg
     3241 gccgcgtcac gcgcaggggt ctcggggaca gggtccggtt cctggggttc cgcggcgacg
     3301 tccccgaact gctgctcggc cacgacgccc tggtgctgcc gtccacgatg gagcagcagc
     3361 cgctcgtggt cgcggaggcg atggcggcgg gcaaacccgt cgtcgccacc gacaccggcg
     3421 gggtcgcgga catgctgggc atccccggcg acgactgccc gaagcccggt gacgtgcccg
     3481 cgctcgccgc acggctgaag gagctcttcg cggatcccga tcccgcgagc accggggacc
     3541 ggctcgccac gagggcacgg gagcggttca ccccggaggt ctgcgcccgc aggcacctcg
     3601 acctctaccg caggctcacc gccgcggacc gttgaccagc accacggcgt cggcggccgg
     3661 caggtcgagc tggggcggca ccggttcgcc gcgcagcgtc acgaggcccg gcggaggcgt
     3721 cagcagcacg gacgtcttcg tcgggttcac ggccacccag ccgttagagt agcggcggtt
     3781 ccacaccccg ctcggcagcc ggttcgccgt ctcgaccgcc tcgccgagcc gcgcgtcctg
     3841 gtacgtcgac cagtacgggt tcttgtagtc gggctgggcc ctggtccagc aggtgtgcgg
     3901 actcgcgagg agcgcggccg aggcgtaccc gacccgctcc tccctgtccg acttcgtgtg
     3961 cgtgatcagc agcagccacg actcgccgag cgcggcctgg gcgcgctgct ccttgaactg
     4021 gttgccctgg aacgtgatca gctcgccggt gccgtcgtcg ccccgcaggc cgaagttctc
     4081 ctccatcgcg cccgcgtacc gggagtgcgc cgaccaccgc cccggtgtca gctgcgactc
     4141 cgagacgttg gggacgagca tcttccccgc cttctccagg gcgtcgccgg tcagttcgag
     4201 catgccgtcg aggccgtcgc gcagcagccg gtccgagccc gcggcgtcgg cggtgcccgc
     4261 gatcacggac ggcgagtagt acttgaggga gctgaagtcg ttgtccgcca gcacgccgtc
     4321 ccagccctcg cgcagcacct cgctgaccac ggcgtccgcc caggccttct ggtaggccgg
     4381 gtcccacacc gtcatctgcc agtgcttcgg gtagccgtcc cactcgatgc gctgcccgag
     4441 cgtgctgatc gcgaaccacc ccggcgtgcg ctccgcggcg ttgtacccga tcccggtcgg
     4501 caggtactgg gcgtcgcggt cgccctcgac cgcgccgttg tagttgcggg tgctggagaa
     4561 gtccttgtaa accagcacct tgaccttggg gttgagctcg tggagtttcc gcatggcggc
     4621 cgtctcccac gcgttgagca ccacgacgtc gtagtgcttc gcggcggctc tgatctccca
     4681 cgccgagggc gagtcgccga tgccgtacca ccaggcgcag ggggccaggg ccttcgggat
     4741 cggccccgtg atgatcgggt ccgactcggc ggcgctgacc gcacatgcac tcgaaagaag
     4801 tacgagggcg acaacggcga atcgacgaat cagcgatttc tccgacaaca caactcaccc
     4861 gctgtcatca gtagaatcct caggtcaagc cacaacgacc aattcgcgat gtagtagttg
     4921 tcgtaccgag acctgtcggc gatggaagtg tcacctcgca gtccgtgcac ctgagcgagt
     4981 cccgtcaagc cggtcggaac gcgatggcgc gcccaatata gctcgtgaat agcggaaaac
     5041 tcgcgaacga aaccgggacg ctccgggcgt ggcccgacga cgcacatgtc gccgcgcagc
     5101 acgttccaca actggggcag ctcgtcgagc gacgtgcggc gcaggaaccg gccgaccggc
     5161 ccgacccgcg agtcgccgac gaccgaccac gtggactgcg agtcgtcctc acccgtctgc
     5221 cggacgctgc ggatcttgta gagcgtgaac gtgcggtcgt ccatgcccac gcggacctgc
     5281 cggaagaaca gcggccggcc gctctcgacc agcaccgcga gcgcgcacag cccgatcacc
     5341 ggcgagagca cgaccagcgc gaacgccgcc agcacgaggt cggcggcgcg cttgatccac
     5401 caggtcggcc tgctggtcgg cgcggtgccg aggcgcatca gcgggtagct gcgcagccgt
     5461 tcgatgccgg ggccgtccgg gtgcagctcg tacatgcggg gcacgacgag cgtcgagcag
     5521 ccgagccggt gcgcggtgat cgcggcctcg accagcggtg agtcgcgggt gtgggagaac
     5581 gcgagcacga cggtgcccgc cttgagccgg acgatcgcgt cggccaggtc gccctcgacc
     5641 acctcgagca gcggcggccg ccggtcggga tcgggcccgg agtcggcgaa cgcgacgggc
     5701 cgcaagccga actgggggtg ctccagcatg gtcttggcga ggttcacgcc gacctcgccc
     5761 gctccgacga tgatcgtgcg gtcgcagcgg tcgaaccggc gccggcacca ccgcccgaac
     5821 gcgaagaccg cccacctcac gggctcgatg accagcgcga actcgatcat cgcccactgc
     5881 gcgccggaga gggcggcctg gtcggagccg ccgaccaggc ccgcgccgga cagcagcgcg
     5941 aaggccagcg cggtgctcgc ggcggaccgg ggcaggtcct gcaaccacga cagccacagc
     6001 cgccgccggt agagccgcca cgtccccctg atcgtgacca ccgaggccac gaccgcggtg
     6061 ctccagcccc accccaggcc gtgccgcacg cacaccacgg cgagcgccgc gaggtccgcg
     6121 aaggcgagca ggacagcgac cgcgttcacc cggctgagca cgtcgcggcc cacggaggac
     6181 ggcttgaggg gccgttgcgc gggccgcagg agctcagcct cgtgggtgag gagcgggtct
     6241 gctggaacgg caaccgccga gaatcgcctc atggaagatc atccgatcga aggagttaga
     6301 gccgcgagag tgcacgaaag agtgaatgag cgctgagaaa tcatctcttc aggtatcaat
     6361 atccctcttc ggtgtcacgc gtgaacgcga atggtgaggt ttcgacgttg ttcctgccct
     6421 gaactcaccc agggccgcct ccaagcttta gcacgcggtg tcaataattc acgccaccaa
     6481 ccacgagcca ccgaagaggg ggcgccagag tgagagtcga cgaacacggc atccggcatt
     6541 cggccggtga gcccgtcgcc atcgtgcaga aaccgatcag cacgtgcggc gacgtccacg
     6601 tcgtcctgcc cgcctacaac gaggccgtgg cgctcccgtc gctgctggcg cgcatcgcgg
     6661 gcaccgacct cgccccccgg atcacggtct gggtcgtcga cgacggctcg tccgacggca
     6721 ccggggcctg cacggcggac gtgcgcgggc tcgacgtccg gctggtgacg catccggtca
     6781 acctcggcct gggtcaggcc gtccaatcag gactgatggc cgcgctcgcc gaggctgcgc
     6841 ccgacgacgt cctgatcgtc atggacgccg acgacacgca cgaccccggt gtgttccccg
     6901 cgatgctggc cgaggtcaag gccggcgcgg acgtcgtgat ctgctcccgg ttcgtcgcgg
     6961 gcggcgacga ctcgacggcc ccgcagtggc ggcggctgct ctcgcgcggt gcccgcgtcg
     7021 tgttcggcaa ggtgctgcac ttcgacggcg tccaggactt cacgagcggc ttccgcgcgt
     7081 accgggtgag cctgctgcgc cgggccgccg cgcactgggg tgagcgcctc gtcgaggaac
     7141 gcgggttcgc ctgcatggtc gagctgctgc tgaagctgcg gcactgcggg ccgatcgtca
     7201 gcgagatccc gctgcacctg cgctacgacc gcaagccggg cgccagcaag ctccggctcg
     7261 gtcgcacgct caagcagtac ctgctcctgc tcacgcgtga ccgcctcgcg cccgttccgt
     7321 tccggaagct ctgatgcccc agcgcgttgt cgtcgtcggc gggggcatct gcggcctcgc
     7381 caccgcccac cggctcgccc gcgagggcct cgccgtgacc ctcctcgagg ccagtgacca
     7441 gctcggcggc ctcggcacgt tcttcacctc gcagggccgt tccgtggaac gcttctacca
     7501 ctgcgtgatg ccgaccgacg cggccctgct ggcgctgctg gacgaggtcg gcctgcgcga
     7561 gagcgtccag tggaacccca ccaccatggg catggtcgtc gagggcgagc accgctcgtt
     7621 caactcggcg ctcgacctgc tggggttccg cccgctgagc ttcgcggacc ggatccgctt
     7681 cggcgtggtc tcggtgctgc tgcgccggtt gggcaagggc aaggacctcg acaacctgcg
     7741 caccgaggac tggctgcgcg gcctgtacgg cgacaggatc tgggagctgt tgctcgctcc
     7801 tctgttcggc gcgaagttcg gctccgcgtt cggcgacgtg cccgcgctct acgtgtggca
     7861 gcgcctgggc cgcgagagca acgagtcggt gcgcggctac ccggccggtg gctacaagag
     7921 cgtgatcgac gcgcttcagg cgtccatcga ggcgcacggc ggcgaggtcc ggacctccgc
     7981 tcccgtcggc aggctggagg cctcgcagga ccgcgtgctg gtcacgctga tcgacggcga
     8041 gacgatcgag gcggaccacg ccgtctccac ggtcccgctg cccgcgctgc ggtccatcgc
     8101 agacccggac ctcgcgccgc ggctgccgga ggtccggctg ccgtaccagg gtgtcgtcaa
     8161 cgcgttgttc ttcctgcgca agcctttgtc cggccactac tgggcacccg tgatccgctc
     8221 gggcacggac ttcgacggcg tgatcgagat gacgccgctc accggctcgg agcgctacgg
     8281 cgaccggcac ctcgtgtacg tcatgcacta cacggaccgc gagtcggcgt tgtaccgcga
     8341 ggactcggac agcatcgccc gccgctggac cgagcagctg ctgagcatcc acgagggact
     8401 gacgccggac gacgtcgacg aggtgcgcgt gttcaaggcg ccgttcgtcg aaccggtgta
     8461 cccgctggga tatctcgcgc agcgcccgcc cgtcgaggtg cccggcaccc ggctgcggct
     8521 cgccaccacg gcccacgtct accccaacgt cacgagctgg aactcgagcg tcgagctgtc
     8581 caactccgtg acggacgcac tcctgcgcga cgccaggagt tcctcgaccc aggaggacac
     8641 cgcatggtca gcagaatcgg cgcggtgatc gcagcactga cgatcaccgc ggtcaacttg
     8701 gtctcctcgc agcacgtcca ggccgatccg gccccgctgc tgcccgatct ccgccaggcg
     8761 cccatcggct gtcccggcgg gcacgacggc gcgccgctgc tgtgccgcgc ctgggacgtc
     8821 tgcctcgtgg aggacgcctc ggcgccgcgt ggcaagtgca tgaaccgcgg tggcagggcc
     8881 caggccgtgc gcctgcggtt caccacctcg atcgacaacg tcggcgacgg cccgctgctg
     8941 ctgcacgcgc accgcgacag caccgccacc cccacgatga gggtccggca ggcggttcag
     9001 tccggtgtgg acggttcgat cgccgggtcg tacaacgagg ccgggcgcga gaccagttcc
     9061 agcgcctatt acgagcccgc gccgacgcac acgcactggc acctgctcaa cttcgagtac
     9121 ttccagctgc gcacacccga cggcggcgtg gtcgtgacgg accgcaagaa cggcttctgc
     9181 atcggcgacc ggtacacggt gtcggacgac ctggagcacc ggccgtccga cccggagagc
     9241 ccggaaggca agctggcaca acgacttcgc ggtcacatgt gcgagcacca caacccgtcc
     9301 gcactggacg tgatgttcgg gatctccgtc ggatcgggcg acgactacaa gtacgaggtc
     9361 gacttccagt ggctggacct cacgaacgtg aagtccggca cctacgacgt cgtgaacgtg
     9421 gtgaacgccg atcgcgcgtt gctggagaag aactacgaca acaacgcggc gtcgatcgcg
     9481 atctcggtgc agtggccggg aggcgcggtg aatccgcccg ccacgatcga cgaggcccct
     9541 tcggtccgca tgatccgcag ttgtccgggc aaagcgcggt gcgcgaagtc gcgcggctga
     9601 tcagttcccg aaacaacccc gaacgggggt gttcgctccg gcgggcgccc ccgttttctt
     9661 ttgtaccggg acaaacgggc gggatgcgga tctcgctacc atatcggccg ccaacgacac
     9721 aaaccttact ctgcgaaacc gacatctgtt gcacatagca cacccatacg cgcagacgca
     9781 attgcgctca atggcaggct caaacacccg agtcaataga ccgagtggtg caatcttcat
     9841 cacagtggag agtgtcgtat gcaaccccct tggctcttga cctggacatg tggccgcttg
     9901 agagaattca cggtgcgatt ccaccccgtc agggattgca agccgacctg attccccggc
     9961 cgatcaggag tgccccatct tgagcgcgcc atccgtctcg ttgcacgatt tcgccattgg
    10021 acaactacac gacctgctcc gcgctgtcgg tttaacgaac tcagccgaaa gcgcgacaga
    10081 actgctgggt gaagcattag gccccggttc ccggcttccc ctctccgcgg ttccccattg
    10141 gccctcatcg gtcgccgacg accacacccc ggtcgaattc tcggtggctt tggctcaaaa
    10201 cgaacccccc gccgtgcgca tgatcgtcga gtcgctcgcc gagcagcccg gccggcaggc
    10261 caacgtcacc gccgcgctgc gggtgctcga cgggctgacc gaacggcacc aggtgcggct
    10321 gcggcagctc gacctggtcc gcgacctgtt cctgcccgaa gacccgcagg gcgcgttcgc
    10381 gttctggtac tcgctgatcg tcgggcccgg tgcgcctccc gccgtcaagg tctacctcaa
    10441 ccccgacgtg cgcggccgtg agagcgcgac cgcactggtc ggcgaggcgc tgtcccgcct
    10501 cggtctgagc gcggccctgc cggccgtgca ggagcacgcg ctgcggcgcg cagggctcga
    10561 ccggttctcc ttcttcgccc tcgacctcat ggaggaggac cgggcgcggg tgaagaccta
    10621 cgtcgcgcac gacgacgccg tggtcgcgga cgtggtgcgc gccgcggccg cggtgcccgc
    10681 ggtcgacccg gcgatcctcg ccgacgtctg cgagctcgcc tgcggcggca cggggccgtt
    10741 ctcccggcgt cccctgatgt cgagctacac gttcctgtcc ggcgacacgg aacggcccag
    10801 cggctactcc ctctacatcc cggtgcgcga ctacgtgcag gacgacctgg aggcgtgcga
    10861 gcgcgtcctg gcgatcatgg ccaggtgcgg gctcgacacg acgccgttcg tgatggcgct
    10921 ggcgagcctc gtccaacgcc cgctcgggga cggcgtcggc ctgatcgccc acgtgtcgct
    10981 gcggctcggc agaccgaagc ccggtgtctc ggtctacctg tcgtcggagg cgtacgacgt
    11041 cacgccgccc cgcaccaaag cactatccgc ttagcgctgc accagaaagg ccaccgccgt
    11101 ggagccgtac cgcatcaagg tcgtcgagcc cattcccatc accacccgcg aacaccggga
    11161 acgccgctac tccgaggccg ggtacaacca gttcaacctg acggcggaag acgtcacgat
    11221 cgacctgctg agcgattccg gcaccggagc gttgtcggcg gagcagcagg ccgccggcat
    11281 gcgcggcgac gagacgtacg cgggctcgcg ctcctggttc cggttccgcg aggtggcctc
    11341 ggacctcacg gggtacgagc acatcctgcc cgtgcaccag ggccgcgctg cggaacgcat
    11401 cctgttcagc gcgttgctca aacccgggca gatctcggtc agcaacacgc acttcgacac
    11461 cacccgggcg aacgtggaac tggcgggcgg cgtggtccgc gacctcccgt caccggcctt
    11521 ctccgacttc gacagcgacg tgccgttcaa gggcgacatc gacctcgtcg cactggaggc
    11581 gttgctggac gggcccgagg acgtcggcct ggtgctcatc acgatcacca acaacggcgg
    11641 tggcggccag ccggtgtcga tggccaacct cgaggccgtg cgcgcgttgt gcggcaagca
    11701 cggcgtgccg ttcatcctcg acgcggcccg gttcgccgag aacgcgtggc tcgtgacgca
    11761 gcgcgaggag cgctaccgcg gccacagccc gcgcgaggtc gcgaagctcg cgttccggct
    11821 cgccgacggg tgcgtgctga gcctgaagaa ggacggcatc gtccacatcg gagggatgct
    11881 cgcgctgcag gacgccgatc tggccaagca gtgcgaactc ctgctgatcg cgaccgaggg
    11941 gttcagcacg tacggcgggc tctccggccg cgacctcgac atgtgcgcgc agggcctggt
    12001 cgaggtgacc gacccgatgt acctgcgcga gcgcgccgac gccacggcgt acctcgcgga
    12061 ctgcgcgcgc gaggccggtg tggacagtgt gcggccgacg ggcgtgcacg cggtctacct
    12121 caacgcggcc cggctcctgc cgcacatccc gccgagccgg ttcaccggcc acgcgctcgc
    12181 gtcggagctg tacctcgcgg gcgggatccg gtgtgcggag gtcggttcgc tctacctcgg
    12241 cgacatcgac ccgtccggcg agctgctcac gcccgcgccg ttcgagctgg tgcggctcgc
    12301 gatcccgcgc cgcgtctaca cccgcagtca cctggagtac gtggcggaga cgctggcggg
    12361 catcgcgagg gacccggagc aggtgcccgg ctaccggctc acggaggtgc cgccgatcct
    12421 gcggccgttc cggtgccggc tggagcagat caggccgtag gaacggctga agcccttggt
    12481 gtgcggcaca ccaagggctt cagcgggcct gcttcaggcc atcacgtcga gccggttcat
    12541 cgcgtgctcg atcacgcgga ccagcaccgc cttgcacgac tcgcggtcgc gggcgtcgca
    12601 cagcaccagc ggcaccgagt ccggcacgtc cagcgccacg cgcagctcct cggtcgtgta
    12661 ggtgtggctg ccctggaagc agttcaccgc cacgacgaac gggatgcccc tgcgctcgaa
    12721 gaagtcgatc gcgccgaagc ccgcgtcgag cctgcgggtg tcgaccagga cgacggcgcc
    12781 gatcgagccg atggcgagct cgtcccacag gaaccagaag cggtcctggc cgggtgtgcc
    12841 gaacaggtag agcaccagtt cggggttgat cgtgatgcgg ccgaagtcga gggcgaccgt
    12901 cgtcgtggtc ttgccctcga cgccgtagag gtcgtcgatc tcctcgccgg cctcggtgag
    12961 cagttcctcg gtccgcagcg gcgtgatctc gctgaccgcg ccgaccatcg tggtcttgcc
    13021 gacgccgaag ccgccggcca cgacgatctt cacggaggtg gggacggaga gttcttccct
    13081 gccctgctca gattgcacgg acaccatcga gcaccttctg gagtaggttc atgtcgaccg
    13141 ggaccacctt cgtggacggg ctgctggtga tgacgtcacc gcgctggatg aggtcgctca
    13201 ggagcacctt caccacgacg agcggcgcgt gcaggtaggc ggcgacctcc gccacggaaa
    13261 gcggtttccg gcagagtttg atgatctcca ggtgctcgac cgagagcgtg ccctggtccg
    13321 tcgtcgtgcg cagcgcccgg acctgggtcg tgagggtcag gtcctcgccc gcgggcttgg
    13381 gcctggtgcg accgctcacc atggcgtagg ggcggaccat ggggcccgcc gcctcgtcgt
    13441 accaccagtc ggaggagttg ctcatgacaa cccgaggggg ttgggcatcc tcggcgaggc
    13501 cattgttcgg ggtgccgagg agaggtaggc gcctacgcgc ttcacgagca tgttcatctc
    13561 gtaggcgatc atgcccatgt cggcgtcctc gtcgcccacc accgcgagac aggcgccctg
    13621 tcccgccgcg gtgacgaaga ggtgcgcgcg ttccatctcc acgatggtct ggcggacctg
    13681 cccacctccg aagtgcctcc cggtgccgcg agcgaggctc tggaacgccg acgccatcgc
    13741 cgagaggtgg tcggagtcgt ccttggagag ctcgggagag tgggcgagca gcaggccgtc
    13801 cgcggagagc accaccgcgt gccgggcacc gaccactctc gcgacgaggt cctccagcag
    13861 ccagttgagc tcggggtgcc cgctggtcag gtcgtccacg gaaatagccc tttcagtatt
    13921 cgtcatcacg gttccacgac gtcgtcggcc tggcgggcgt cacgggttcc ccgctggaac
    13981 gcggccatgc cgtcgcgggt gcgttccgcc cgttcctcgg ggttgaactc cgcgagttcg
    14041 ggcatcggcc ggaggtcgtc gttggccaac tgcggtacga ggtgctgctg ccgcctccgg
    14101 cgcggcagct cgggccgggc gttctggcgc gtcgtctcac cttccgccgg gtcgtcggtc
    14161 ggccaggcgc ctgcctggcg gtcgtcccgg ggcagctcga gctgcccgct gttgctgtcc
    14221 agatcccttt ccgggtctgg ggcgtggccg tttcccactg ccctgccggc ccagaactcg
    14281 tccagctgga acgtctcggt ggggcgctcg gccggcaggg actcgtgcgt caggtcgccc
    14341 tgcagcggga ccgcggcctc cagggcctcg ggcgagcgcg cggcctgctg catcgtctgc
    14401 tggcggaacg tcggcttcgg catctgcacc gagtccgcgg ggtccaccgc gcccgcctcg
    14461 ccgacgatca gctcggacgg gatcaggacc agcgcgatgg tgccgccgga cgggcagtcg
    14521 cgcagctcga cgtggatgtg gcggcgcgcg gccagccggg cgacgacgaa gaggcccagg
    14581 cgggactcgc cgcgcagcct catcgcctcg aagtccggcg gcgcctccag catctggttg
    14641 tgctgctcgc ggtcctcggg cttgatgccg aggccgtggt cctcgatctc gatgacgagg
    14701 ccctgcggca cctcgctgct gtggatctcg acctgcgagc gcggcgagga gaacgacgtc
    14761 gcgttgtcga cgagctcggc gatcaggtgg atcgtgtccg cgacggcggc gccgaccagc
    14821 gcgacctcgg gcaccgggtt caccttcacg cgggcgtact gctcggtctc cgcgacggcg
    14881 gcgcggacga cgtcgagcat gcgcacgggc ttgcgccact gcctgcccgg ctgctcgccg
    14941 gtcaggatga tcaggttctc ggcgttgcgg cgggcgcggg tcgcgaggtg gtcgagctgg
    15001 aagaacgcgt cgaggtggtc ggggttctcc tcctcgcgct ccagcttgtc gaggatcttg
    15061 agctggcggt gcacgagacc ctggttgcgg cgcgcgatgt cgaggaagac ccggttcacg
    15121 ccctcacggg tctgcgactc cttcacggcc gcggcgacgg cggtgtactg cgcggcgttg
    15181 aacgcgtcgg ccacctgccc gatctcgtcg ttgccgtagt cgagcgcggg gacctcggcg
    15241 gcgacgtcga cgtgcttgcc gtcgcgcagc cgctcgacga tgtccggcag ccgctcgtgg
    15301 gcgagcttca gcgagtcgct cttcaggctg atcaggcgga cgatcaacgc cttgttgacc
    15361 agtcggttcg acacgcgcac ggcgacgaag atgccggcga tgaccgcgat cagggcgatg
    15421 agggagccga tgaggacggt ggtgaacttc tccttgccgt tcgccatggc gatgttgacg
    15481 gcgccggtgg actgctcctg caccatcgtg acgatctcct gcgagaccgc gcgggtggcg
    15541 ttctcgaagt ccgccagggt gacctgctgc ccgacgggcc gttccgagtt ctgcagcagg
    15601 cggttctcga acgtcaccag ctgctggtac ggcgcgctgc cggtgagctg cttgtagtgc
    15661 tcgcgcacgt ccggcagcgc gacgggctcg atgacgttca gcgtgaagtg gtacgcgccg
    15721 acgaggttga cgtactcgcg gtgctcctcc ggcgtgaact tgcccgccgc gatcgcaccg
    15781 gcggcgaccg agctggcccg cgacatcgcg tcggaggcct ggaaggcctg caacgcggtc
    15841 agcgcgccct gcacggtctc ggcgtcgggc acgatgcggg cctgcgtgcc gaacagcgag
    15901 ccgccggcgt cgagcacgct gttgtagtag cggtagacct cgtccttgga cgagttgccg
    15961 gactcgaggc gctcgcgctg gtccggcagc tggtcgagca gcccgttgag cttgttgatg
    16021 ccgtcgacga tctcctgcgg cgcctgcgag gcgagctcac cgaaggccgc cttcatcttc
    16081 tcgacgtcct tgtcggtgtc ctgctgctgc ttgagcaacg ccgacgaggt cgcgccggaa
    16141 cggctcaggc tcgtcatgct gagctcgcgt tccttctgca gcgacgcgaa ggactgcacg
    16201 gcggggatcg acgcgtcccg cgcgccggag gcgaccagct ggaggtagag accctcgaac
    16261 accgtgtacg acgagaacag cgcccacatg gccagaagga cgacgctggg aaccaccacg
    16321 acaccagtga gccgagaacg aattgtcttg taattcgtct caggcacgtt cttcagcttc
    16381 acaacgctcc acgaccaccc gaattggcga cggaaagata gcactgcaag atcaacacta
    16441 tcaacagcga tgatcttgag gggtgagagc agagtactca gtcagatgcg cagcgcaaca
    16501 ccccctatcc gagttcaggt gacctgtcgc gttgggggaa ggcgttctga caggtagggg
    16561 cgctccccct cgaccgagcg gacgaaagcg gcaccgagct gggctttcgt tgcacgacac
    16621 tgggaacgag ccccctaatg ggcggcaact tgacacggtc gcgggccgtc ttctaagcaa
    16681 gaacgcagcg cgaccggatg ttgctttccg tcaccggcac ttattcggaa tttcgcatgc
    16741 ggatctcgcg accgagcgtg atcaactccg ccattacccc gtcgtgatct tggagttcga
    16801 caccctccgg aacgcgtcaa ttccgctggt catcgccgtg ctgagacggg cgggcaggcg
    16861 ttacggcgcg gcacacccgc ctgccgcagt gtcctgggcc acacggcgac cgccactact
    16921 ccgtccgggt aacccaccgc cacgggcacc gacactctgc gcgattcctg tccgtttcct
    16981 gcccgtaccg aaccccctaa caagaaggat tggcgtggaa tagaaaactt ctcgtcctgt
    17041 ccgggagttc ccgcaagttc tccgaccgcc gtgaacgcga gttcctttct ccttcacccg
    17101 cggccatcag cgcgtacgac ttgtacggcg ctcctcccgt gcctgctcga tgcgctcctc
    17161 cagctcctcg aaccaccgcc ggccctgtgc gccgcagttg tcgcggatct cgtgcttgag
    17221 ctcggacgtg ttcgcgttca ggtcgcggac catgcccagc ccgtggtcga cctgcgcacg
    17281 cagttcgccg cacgacgtcg ccaggtgcgt cgccgcggcg cgcatctcgg cgcgggcgcg
    17341 tctgctcacg gtcagctgga gcgccgcgct cctggcccgg cggaccagcg gcgacatggt
    17401 gcgcagcgag gtctgcgcgg aggtgtaggc gaggtgcgcg gtgtcggcgc actggtagga
    17461 ctcgcggtgg aagacgcgca gcgaatggaa ctcgacctcg ccacgccggt tccggaccgg
    17521 ggcacgagct tggagcttca ccaggcgcgc ctgcacctgt tcggcctggc ggtgcacctt
    17581 ggcgttctcg gcgtggacgc gcttgagcgc tcggtcggcc tgagcggcgg cctcccgcac
    17641 ctcctcgacg gtgacgcgac gggcacggcg gtcccacaac gccatcacga cgagcacggc
    17701 cactgcggtc agggacgcgg tacccacgaa cggcaggtcg ctgttctgca cgacgtactc
    17761 gccgggggcg ttcttctggt aggcgacgag gttcgtggcg gcgagcagga ccagaccgtg
    17821 cgccagcagc cctgcccacc gcttccccgg cggggctccg cgcaccctgc cgtcgcgccg
    17881 gaacacggac cggaccacca gcacgctcaa cggcaccgag aaggccgcgc cccacagcca
    17941 ttcgcgtggg tggaacacct gctccggcac gccgtccacg gcggtgcgca acgcgatggc
    18001 gggcgacacc aggaccagcg ccagcggcag ccagaagaac agggcgagga acgcgagcgc
    18061 gcagcccccg cagccgctcc tgttgcggct caccggcggc ggcgcggctt gcgggcgggc
    18121 gcgagcgcgg tggcaccgga tccgttgagc accttgtcga tgacgtccgc gacgccgccg
    18181 gtgagctcgg tgtggtgctg cacgagcatg gtcgtgaagt gctgggtcag gtcgatgtac
    18241 gcgcggcgct cggccagttc gatgcccggc ttcacggtcg cgcgctgcat gttcaccatg
    18301 cactcgcgca acgccgccgc gctcctgtcg gctctcccga gctccttgcg catgctgcgc
    18361 agggaggcgg tggactcgcg gcggcgctgg tgcagcaccg cgagcttgac ctccctgtcg
    18421 tccaccgccg ccgcctcggt gatccggcgg atctcggtgg ccagcgcgta cgtctccgct
    18481 acgcaccggc cggcgtcgcc gagcggttcc agctgctcgg cgacgcggga cagggcgtcg
    18541 gtgaacccga cgtccttgcc gttgacggtg accagaccca tggaccactc atccgcgcgg
    18601 cggcgcggag cgttacagcc cgaacgaggt ccggctcagg gcgtgaggat cgcgcggccc
    18661 cgcacgcgtc ctgcgtcgag gtcgtcgatc gcgtcctgga acctgtcgag cgggtacttc
    18721 tgcgtgtgca gtgtgacctt cccctgcgcc gccagcacca tcagctcgca caggtcgttg
    18781 taggagccga cgaggttgcc gatcaggttg atctccgtgg agatgatgtc gatcgtcggg
    18841 acgtcgatgt tctcgccgta gccgacgacg tggtagtcgc ccgcgcgccg cagcatcgcc
    18901 acgccgtcct tcgtcgcgcc gccctcgccg acgaagtcga tgacggtctc ggcaccgttg
    18961 ccgccggtga ggtcgaggac cgcggagacg tgcgagccgt ccgcgacgac gccgtggtcg
    19021 gcgccgatcg tctcggcgag cttcaccgcg tccgggttgc ggtccacgac gacgatctcg
    19081 gccgccgtca gcgccttcag cacctgcacg ccgatgtgcc cgaggccgcc ggcgccgatc
    19141 accacgcacc ggtcccccgg ccgcagcctg cgcgccgcct tggccgccgc gtggtacgcg
    19201 gtgaggcccg cgtcggcgag cgccgccacg tcggagggct ccagcgcgtc gtcgatcttc
    19261 acgacgctgc gggccgacgt cttcaggtac tccgcgtagc cgcccgcggt gtcgatgccg
    19321 gggaactgcg aggcggcgca gtgcacgtcg tcgccgctgc ggcaggcccg gcacaggccg
    19381 cacgtgatca gcgggtgcac gatcaccttg tcgcccacgg cgacgttcgt gacggccgag
    19441 ccgacctcgt gcacccagcc cgcgttctcg tggccgatcg tgtacggcag ggcgacgccg
    19501 gacttctccg cccactggcc ctcgaggatg tgcaggtccg tgcggcacac gcccgcgccg
    19561 ccgatgcgca cgaccacgtc gaacgggccg gtcgccttcg gctgctcgac ctcggtgagc
    19621 gccaacggct ggtggtagcc gactacctgg acggccttca tgccgattcc tccattgcgt
    19681 aacgggtgcg gagcaggccg cggcagaagt gcgcgttgcc ctcgatggaa atgccgaccg
    19741 accgggcgaa ccgcagccgc agcggcaact ggcccgcggg caggggcacg ccgtggtcgt
    19801 cgacgagcac cggcgcgtcc ggcgaggtgt cgaagccgag cgcggaccgc ctgcgccgca
    19861 acgcctccgc cgccttggtc gccgggaggt ccttcagcgt caacgacctc aggcggtcga
    19921 ccggcacgtc gcgcacggcc cgttccatcg ccgccgcgtg cgccttgcgc tggaacgtga
    19981 gccgcagctc ttcgagttct cgcgacgcct cttcgccgta cgtgccgacg aatcccgaat
    20041 ccgccgcgat gccgcggttg atcacgtccg agtcgtggtg gtcgtccagc accacgacca
    20101 cgtgcggggc caggtcgcgc agcacgtcct tcgagtccga cgccatgagg tacgcgaagt
    20161 tcggcgagca gaacgccgtc ggcagtcgca ggtggacggt cagcacgtca ccgtccagct
    20221 cgaccgagcg gacgaacccg agcgtggtga tcggctcgtc cagctcgggg tccatcacct
    20281 cgtcgagcgc ctggaacacg gcggtgtcga tcatgcgacg gccaccgcct cctgctcgac
    20341 cggcgcgacg tcgagaccgg cgggcaccgg gatgtcgtac aggtgcgccg cgttgaggcc
    20401 gaggatcttc ttcttctggg ccacggtgag cggcgcgtac tcggtcatgt cctcggggat
    20461 ctggaagtcc acgaagctct cgaccagcca gcgcggcgtc cacagcgcgt agtcgctgga
    20521 gaactggatc ctgtcctcgt tcagccagta cagcagctcg ccgatgatct gcgcgaagta
    20581 gcgcggccgg gtgtggatga acggcatcgc gaccgcgaga ccggcgtgca cgttcggttc
    20641 ctgcgtggcg atccagcaga agtcctccag gcgcggcagc ccgcagtgct cgaccacgaa
    20701 gttcatctcg gggaagtccg tcgccacgtg gtcgacgtcg gccacgtcga acgcgtcccg
    20761 gtcgagcggc cggatcgtgg gccccttgtg cacgtggatg ttgcggatgc cgagctcctg
    20821 cgcggcctcc aggtacttgt agctccacgg gtcgtcgagc cggtagccgc gcgagtcgcc
    20881 gtaccactcg gccgtgtaga gcttcactcc cttgagcccg aaccgttccg cgtcgcgctt
    20941 gagctcgtcg agccccttct gctcgcggcg cgggtcccag cagtggttgt aggtgagctt
    21001 gtccgggtgc ttcgaggtga gcgcccacgc ttcctcggtc tgcccgaaac cgttgtggta
    21061 gaaggcaccg aggt
//
