LOCUS       NZ_CP099738            31430 bp    DNA     circular CON 27-AUG-2024
DEFINITION  Lentzea sp. HUAS12 chromosome.
ACCESSION   NZ_CP099738
VERSION     NZ_CP099738.1
KEYWORDS    RefSeq.
SOURCE      Lentzea sp. HUAS12
  ORGANISM  Lentzea sp. HUAS12
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 9676923)
  AUTHORS   Ping,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JUN-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024125735.1-RS_2024_08_27
            Annotation Date                   :: 08/27/2024 06:34:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,161
            CDSs (total)                      :: 9,080
            Genes (coding)                    :: 8,988
            CDSs (with protein)               :: 8,988
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 21 of 92
            Pseudo Genes (incomplete)         :: 77 of 92
            Pseudo Genes (internal stop)      :: 3 of 92
            Pseudo Genes (multiple problems)  :: 8 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:47:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2908070
            Orig. end                         :: 2939500
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP099738.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Ping Mo.
FEATURES             Location/Qualifiers
     region          1..31430
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="16"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..31430
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31430
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:21430]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..21430
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     misc_feature    complement(700..713)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.74"
                     /tool="antismash"
     misc_feature    complement(835..846)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.75"
                     /tool="antismash"
     gene            complement(1463..2317)
                     /locus_tag="ND450_RS12755"
                     /old_locus_tag="ND450_12755"
     CDS             complement(1463..2317)
                     /NRPS_PKS="Domain: PKS_KR (3-163). E-value: 1.5e-12. Score:
                     39.8. Matches aSDomain:
                     nrpspksdomains_ND450_RS12755_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332893.1"
                     /locus_tag="ND450_RS12755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12755"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_253326350.1"
                     /transl_table=11
                     /translation="MSRVVIVTGAGRGIGRAHALAFGAAGCRVVVNDLSAAVAGEVADQ
                     IGPRAVVNTDDVGTWAGARRLVETAVSSFGGLDVLVNNAGIVRDRMVVGCSEDEWDEVV
                     RVHLKGHFATLHHAAAHWRGVAKAGGAVSGRVINTSSGAGLFGSVGQANYSAAKAGIAS
                     MTLVAAAELARYGVTVNAIAPAARTRMTEATFADMMAPPEDGFDAMAPENISPLVVWLG
                     SEEAGDVTGRMFEVDGGRVCVVHGWRRGPEVDKGARWSVEELGAVVRKLVADDHPVPVY
                     GAE"
     aSDomain        complement(1829..2308)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ND450_RS12755_PKS_KR.1"
                     /evalue="1.50E-12"
                     /label="ND450_RS12755_PKS_KR.1"
                     /locus_tag="ND450_RS12755"
                     /protein_end="163"
                     /protein_start="3"
                     /score="39.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVIVTGAGRGIGRAHALAFGAAGCRVVVNDLSAAVAGEVADQIGP
                     RAVVNTDDVGTWAGARRLVETAVSSFGGLDVLVNNAGIVRDRMVVGCSEDEWDEVVRVH
                     LKGHFATLHHAAAHWRGVAKAGGAVSGRVINTSSGAGLFGSVGQANYSAAKAGIAS"
     CDS_motif       complement(1847..1903)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ND450_RS12755_0001"
                     /evalue="5.70E-07"
                     /label="PKSI-KR_m4"
                     /locus_tag="ND450_RS12755"
                     /protein_end="157"
                     /protein_start="138"
                     /score="22.1"
                     /tool="antismash"
                     /translation="TSSGAGLFGSVGQANYSAA"
     gene            complement(2314..3072)
                     /locus_tag="ND450_RS12760"
                     /old_locus_tag="ND450_12760"
     CDS             complement(2314..3072)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (10-160). E-value: 3.8e-09.
                     Score: 28.6. Matches aSDomain:
                     nrpspksdomains_ND450_RS12760_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020671816.1"
                     /locus_tag="ND450_RS12760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12760"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_253326351.1"
                     /sec_met_domain="adh_short (E-value: 1.3e-31, bitscore:
                     109.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4.4e-36, bitscore:
                     124.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVELDLHGAVVLVTGGVRGVGLGITRAFLSAGATVVTCARRPAE
                     VDGASFVPCDVRDADQVSELVSGIVAEHGRVDVVVNNAGGAPFALADKASPRFHSKIVE
                     LNLLAPLLVSQAANEVMQEQGSGSIVNVSSVSGRRPSPGTAAYGAAKAGLDSLTSSLAV
                     EWAPKVRVNALAVGMVRTEQSHLHYGSEAGIEAVARTVPLGRLASPDEVGACAVFLASP
                     LASYVSGATLVVHGGGEAPAFLTAADGGTA"
     aSDomain        complement(2593..3042)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ND450_RS12760_PKS_KR.1"
                     /evalue="3.80E-09"
                     /label="ND450_RS12760_PKS_KR.1"
                     /locus_tag="ND450_RS12760"
                     /protein_end="160"
                     /protein_start="10"
                     /score="28.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVLVTGGVRGVGLGITRAFLSAGATVVTCARRPAEVDGASFVPCD
                     VRDADQVSELVSGIVAEHGRVDVVVNNAGGAPFALADKASPRFHSKIVELNLLAPLLVS
                     QAANEVMQEQGSGSIVNVSSVSGRRPSPGTAAYGAAKAGLDSLTSS"
     CDS_motif       complement(2599..2676)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ND450_RS12760_0002"
                     /evalue="1.30E-04"
                     /label="PKSI-KR_m4"
                     /locus_tag="ND450_RS12760"
                     /protein_end="158"
                     /protein_start="132"
                     /score="14.5"
                     /tool="antismash"
                     /translation="SSVSGRRPSPGTAAYGAAKAGLDSLT"
     CDS_motif       complement(2962..3042)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ND450_RS12760_0001"
                     /evalue="3.50E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="ND450_RS12760"
                     /protein_end="37"
                     /protein_start="10"
                     /score="10.0"
                     /tool="antismash"
                     /translation="VVLVTGGVRGVGLGITRAFLSAGATVV"
     gene            3136..3903
                     /locus_tag="ND450_RS12765"
                     /old_locus_tag="ND450_12765"
     CDS             3136..3903
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (7-210). E-value: 5.9e-47. Score:
                     152.0. Matches aSDomain:
                     nrpspksdomains_ND450_RS12765_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019809646.1"
                     /locus_tag="ND450_RS12765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12765"
                     /product="enoyl-CoA hydratase family protein"
                     /protein_id="WP_253326352.1"
                     /transl_table=11
                     /translation="MGISSSHTENGIIEVTVDYPPVNAIPSQGWFELARAVTAAGEDPD
                     ARVVVLRAENRGFCAGVDLKEIQRAEGYNALVAANRGCAKAFAAVYDCEVPVIAAVNGF
                     CLGGGVGLVGNADIIVASDDATFGLPEVDRGALGAATHLARLVPQHLMRTLYYTARNVS
                     AQTLHHHGSVVEVVPRAQLDEAAREIAGEIAKKDTSVIRAAKEAINGIDPQRVHQSYRF
                     EQGFTFELNLTGVSDHARQAFLDGHHARQANDG"
     aSDomain        3157..3765
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ND450_RS12765_ECH.1"
                     /evalue="5.90E-47"
                     /label="ND450_RS12765_ECH.1"
                     /locus_tag="ND450_RS12765"
                     /protein_end="210"
                     /protein_start="7"
                     /score="152.0"
                     /tool="antismash"
                     /translation="TENGIIEVTVDYPPVNAIPSQGWFELARAVTAAGEDPDARVVVLR
                     AENRGFCAGVDLKEIQRAEGYNALVAANRGCAKAFAAVYDCEVPVIAAVNGFCLGGGVG
                     LVGNADIIVASDDATFGLPEVDRGALGAATHLARLVPQHLMRTLYYTARNVSAQTLHHH
                     GSVVEVVPRAQLDEAAREIAGEIAKKDTSVIRAAKEAING"
     misc_feature    3160..3171
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.43"
                     /tool="antismash"
     gene            3878..4675
                     /locus_tag="ND450_RS12770"
                     /old_locus_tag="ND450_12770"
     CDS             3878..4675
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033633.1"
                     /locus_tag="ND450_RS12770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12770"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_253326353.1"
                     /transl_table=11
                     /translation="MRDKRMTADEVVGTIKDGMTVGIGGWGSRRKPMTLVKALLKSPAT
                     DLTVVTYGGPDAGLLCAAGKVRKLVYGFVSLDSIPYDPWFKRARETGAIEVLELDEGMF
                     QTGLRAAAHRLPFLPIRAGLGSDVLKYAPELKTVRSPYDDGEELVAMPALKLDVALVHL
                     NRADKHGNAQYLGPDPYFDDLFCLAADRRYVSCEQVVESFDGPPQTLLLNRMMVDGVVQ
                     APGGAGFTSCVPDYGRDEALQREYANAATDLEQWPDFYERFLE"
     gene            4672..5385
                     /locus_tag="ND450_RS12775"
                     /old_locus_tag="ND450_12775"
     CDS             4672..5385
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033634.1"
                     /locus_tag="ND450_RS12775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12775"
                     /product="CoA-transferase subunit beta"
                     /protein_id="WP_253326354.1"
                     /transl_table=11
                     /translation="MSDITRAEVCVAACADLFLGAGETLASPMGLIPSLGAKLARLTDE
                     PDLLLSDGEAFLLTPESTVEGWLPYRKVFDVVAHGRRHVVMGANQVDRFGNQNISAIGD
                     HARPTRQLLGFRGAPGNTVNHRTSYWVPRHSPRVLVEAVDVVSGVGYDRAAGPFHDVHR
                     VVTNLAVLDFGTPDHSMRIVSVHPGVSVDEVQKQTSFPLVAEDVGETRLPTGGELDLIR
                     TRLDPQGKRDKEVPS"
     gene            5382..6431
                     /locus_tag="ND450_RS12780"
                     /old_locus_tag="ND450_12780"
     CDS             5382..6431
                     /EC_number="1.13.12.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033635.1"
                     /locus_tag="ND450_RS12780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12780"
                     /product="nitronate monooxygenase family protein"
                     /protein_id="WP_253326355.1"
                     /transl_table=11
                     /translation="MRTALTELVGVRHPVVQTGMGWVAGPRLVSATAEAGGLGILASAT
                     MTYPELEAAIKETRSRTSAPFGVNLRADAHDAPERIDLLIREQVKVASFALAPKPDMIA
                     KLNDAGVVVIPSIGAARHAEKVAQWGAHAVIVQGGEGGGHTGGVATTLLLPSVLDAVDI
                     PVVAAGGFFDGRGLAAALAYGAAGIAMGTRFLLTRESTVPDAVKHAYLHRDLNGTVVTT
                     RVDGLPHRVLRSDLVEHLERSGRISGLARAVANAARFRQHTGLTWRAMIREGLAMKHGR
                     DLTWSQVVMAANTPMLLRAGLVEGRTDAGVLASGQVAGLLGDLPTCADLVEGIVKDAEA
                     AIDRLRDVR"
     gene            complement(6415..7560)
                     /locus_tag="ND450_RS12785"
                     /old_locus_tag="ND450_12785"
     CDS             complement(6415..7560)
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033648.1"
                     /locus_tag="ND450_RS12785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12785"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_253326356.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 5.8e-07, bitscore:
                     28.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEAYIIEAVRTPAGRRGGELSHVHPADLGAHVITALLNRVDVDP
                     TDVDDVIFGCVDTVGPQAGDIARTSWLAAGFPEQVPGVTVDRQCGSSQQALHFAAQAVM
                     SGTADVVVAGGVQNMSQVPIGSAMTAGSQVGSPFEGCEGWQHRYGDEEVSQFRAADLIA
                     VRWDLSRREMEDFALQSHLRAITAIKEGRFDREIAPVNGIAADECPRPDTSAEKMAKLQ
                     PLRPGGRTTAALSSQISDGASAVLVVSEQAVREHKLTPRARVHHMSARGSDPIYMLTAP
                     IRATKYALERAGMSISDIDLFEINEAFASVAMAWAKELKVDLGRVNVNGGALALGHPIG
                     ATGTKLFTTLLHELERTGGRYGLQTMCEGGGQANVTIIERL"
     gene            complement(7579..8175)
                     /locus_tag="ND450_RS12790"
                     /old_locus_tag="ND450_12790"
     CDS             complement(7579..8175)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009153717.1"
                     /locus_tag="ND450_RS12790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12790"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_256557497.1"
                     /transl_table=11
                     /translation="MSTRRQELLALAARMFAERGYGQTTVRDIADAAGILSGSLYHHFD
                     SKESMVDEILRTFLDELFTRYREIVDAGLGPKQTLKALVVASFESIDTRHAAVAIYQNE
                     AKHLTGLERFSYIDDRSVEFRKLWTVLLEEGISAGVFRADLDVDVAYRFIRDTVWVAVR
                     WYRPDGELRAEAVADQYLAILLDGIATGRRKNSKT"
     gene            complement(8189..8932)
                     /locus_tag="ND450_RS12795"
                     /old_locus_tag="ND450_12795"
     CDS             complement(8189..8932)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (20-167). E-value: 2.2e-14.
                     Score: 45.7. Matches aSDomain:
                     nrpspksdomains_ND450_RS12795_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020495484.1"
                     /locus_tag="ND450_RS12795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12795"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_253326357.1"
                     /sec_met_domain="adh_short (E-value: 2.9e-34, bitscore:
                     117.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 6.2e-32, bitscore:
                     110.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGHDLLRDKVVVVTAAAGTGIGSATARRCLEEGATVVISDWHER
                     RLKETHKALGTAHAVPCDVTDEQQVQHLVDETVERYGRIDVMVNNAGLGGEKSVLDMTD
                     DEWAKVLDVTLNGTFRCTRAALRRMVVQRSGVVVNNSSVIGWRAQKGQAHYAAAKAGVM
                     ALTRCAAMDVAEHGIRVNAVAPSLAAHPFLTKVTSEELLTELASREAFGRAAEPWEVAN
                     VIVFLASDYSSYLTGEVVSVSSQHP"
     aSDomain        complement(8432..8872)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ND450_RS12795_PKS_KR.1"
                     /evalue="2.20E-14"
                     /label="ND450_RS12795_PKS_KR.1"
                     /locus_tag="ND450_RS12795"
                     /protein_end="167"
                     /protein_start="20"
                     /score="45.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="GIGSATARRCLEEGATVVISDWHERRLKETHKALGTAHAVPCDVT
                     DEQQVQHLVDETVERYGRIDVMVNNAGLGGEKSVLDMTDDEWAKVLDVTLNGTFRCTRA
                     ALRRMVVQRSGVVVNNSSVIGWRAQKGQAHYAAAKAGVMALTR"
     misc_feature    complement(8555..8557)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8929..10002)
                     /locus_tag="ND450_RS12800"
                     /old_locus_tag="ND450_12800"
     CDS             complement(8929..10002)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020495485.1"
                     /locus_tag="ND450_RS12800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12800"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_253326358.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.2e-12, bitscore:
                     46.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7.5e-27, bitscore:
                     92.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.8e-20, bitscore:
                     72.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESFRREVREWLSANLVGEFAELRGLGGPGREHEAFEGRLRWHRH
                     LARSGWTCLGWPGDRSVEEQVVFHEEYAEADAPAKVDIVGEGLLGPTLLAFGTPEQKAR
                     FLPKIRALDELWCQGYSEPGAGSDLASVQTRATLDGDRWVINGQKIWTSNAHYSDWIFV
                     LCRTEPGSQRHHGLSYLLVPMNQPGVEVRPIRQLTGTSEFNEVFFDEAVTARTNVVGEP
                     GEGWKIAMATLGFERGTAMLGHQVGFRRQLDAIMATNPDDERLTRAWLELHVMRSHTMR
                     TLNDEPGPEASVLKLFWGSWHRRLGELAMDSLGPESMIDDNEWQRLFLFSRAETIYGGS
                     DEIQREIIAHRVLGLPR"
     gene            10001..11521
                     /locus_tag="ND450_RS12805"
                     /old_locus_tag="ND450_12805"
     CDS             10001..11521
                     /NRPS_PKS="Domain: AMP-binding (29-410). E-value: 2.9e-90.
                     Score: 294.7. Matches aSDomain:
                     nrpspksdomains_ND450_RS12805_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009153714.1"
                     /locus_tag="ND450_RS12805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12805"
                     /product="FadD3 family acyl-CoA ligase"
                     /protein_id="WP_256557498.1"
                     /sec_met_domain="AMP-binding (E-value: 7.5e-96, bitscore:
                     320.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGHTLTYQALALEGVVAVDPSRQTVSAVLDRAAASYIDAEALVDG
                     EVRLSWLELRSAVLDAARALVGTGVRPGDRVALCAPNSARWVVAALGALRAGAALVPIN
                     TRFTATETLDVLRRSAARVLVVEGEFLGRDREAELRALSPELPAVVRLPATWVPADVDL
                     PELSGEALCDVMFTSGTTGRSKGAMSAHRQSIGVAEAWAACGELTSADRYLVVNPFFHT
                     FGYKAGILACLLTGATIVPQPVFDVVETMRLVERERITVLPGPPTIFQTLLDHPDRGSF
                     DLSSLRLAVTGAAVVPVVLIERMRAELSLTVLTAYGLTEAVVATMCRPGDSPETVADTC
                     GAPMAGFELRLGARDEVLLRGPNVMLGYLDDPVATAEAVDADGWLHTGDVGRLDSRGYL
                     SITDRLKDMYICGGFNVYPAEVEQALARLPGVAEVAVVGRADARLGEVGLAFVVTAPGS
                     SLSESDVIAFCRERLANYKVPRAVEFVPALPRNAMGKVLKTQLRKENA"
     aSDomain        10088..11230
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ND450_RS12805_AMP-binding.1"
                     /evalue="2.90E-90"
                     /label="ND450_RS12805_AMP-binding.1"
                     /locus_tag="ND450_RS12805"
                     /protein_end="410"
                     /protein_start="29"
                     /score="294.7"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="DRAAASYIDAEALVDGEVRLSWLELRSAVLDAARALVGTGVRPGD
                     RVALCAPNSARWVVAALGALRAGAALVPINTRFTATETLDVLRRSAARVLVVEGEFLGR
                     DREAELRALSPELPAVVRLPATWVPADVDLPELSGEALCDVMFTSGTTGRSKGAMSAHR
                     QSIGVAEAWAACGELTSADRYLVVNPFFHTFGYKAGILACLLTGATIVPQPVFDVVETM
                     RLVERERITVLPGPPTIFQTLLDHPDRGSFDLSSLRLAVTGAAVVPVVLIERMRAELSL
                     TVLTAYGLTEAVVATMCRPGDSPETVADTCGAPMAGFELRLGARDEVLLRGPNVMLGYL
                     DDPVATAEAVDADGWLHTGDVGRLDSRGYLSITDRLKDMYI"
     CDS_motif       10271..10309
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ND450_RS12805_0001"
                     /evalue="7.20E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ND450_RS12805"
                     /protein_end="103"
                     /protein_start="90"
                     /score="10.1"
                     /tool="antismash"
                     /translation="LGALRAGAALVPI"
     CDS_motif       10442..10480
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ND450_RS12805_0002"
                     /evalue="2.70E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ND450_RS12805"
                     /protein_end="160"
                     /protein_start="147"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="AVVRLPATWVPAD"
     CDS_motif       10520..10573
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ND450_RS12805_0003"
                     /evalue="1.80E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="ND450_RS12805"
                     /protein_end="191"
                     /protein_start="173"
                     /score="17.5"
                     /tool="antismash"
                     /translation="VMFTSGTTGRSKGAMSAH"
     CDS_motif       10586..10612
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ND450_RS12805_0004"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ND450_RS12805"
                     /protein_end="204"
                     /protein_start="195"
                     /score="-3.3"
                     /tool="antismash"
                     /translation="GVAEAWAAC"
     CDS_motif       10688..10723
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ND450_RS12805_0005"
                     /evalue="1.30E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="ND450_RS12805"
                     /protein_end="241"
                     /protein_start="229"
                     /score="6.2"
                     /tool="antismash"
                     /translation="LACLLTGATIVP"
     CDS_motif       10871..10894
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ND450_RS12805_0006"
                     /evalue="1.20E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ND450_RS12805"
                     /protein_end="298"
                     /protein_start="290"
                     /score="0.4"
                     /tool="antismash"
                     /translation="TGAAVVPV"
     CDS_motif       11066..11197
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ND450_RS12805_0007"
                     /evalue="1.30E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="ND450_RS12805"
                     /protein_end="399"
                     /protein_start="355"
                     /score="17.6"
                     /tool="antismash"
                     /translation="EVLLRGPNVMLGYLDDPVATAEAVDADGWLHTGDVGRLDSRGYL"
     gene            11518..12348
                     /locus_tag="ND450_RS12810"
                     /old_locus_tag="ND450_12810"
     CDS             11518..12348
                     /NRPS_PKS="Domain: ECH (4-231). E-value: 2e-30. Score:
                     97.8. Matches aSDomain: nrpspksdomains_ND450_RS12810_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332869.1"
                     /locus_tag="ND450_RS12810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12810"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_253326360.1"
                     /transl_table=11
                     /translation="MTVSYERRDAVAVVTMNRPEYRNAQNSAMTYALDEAFTRAVDDDE
                     VKVIVLAGAGDHFSAGHDIGSPGRDVDVSFERRAVMWWDHVGREGGDLRFAREMEVYLG
                     MCRRWREIPKPTIAMVQGACVAGGLMLAWVCDLIVASEDAFFADPVVRMGIPGVEYFAH
                     PWVLGPRAAKEVLFTGDRFSAQRAYEWGMVSRVVPRASLESSVFELAGRISAMPRFGLA
                     LAKKAVNQSEDLMGLRAGMDSVFGLHHFAHAHNAEVSSDALAGMDARAMKKASG"
     aSDomain        11530..12210
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ND450_RS12810_ECH.1"
                     /evalue="2.00E-30"
                     /label="ND450_RS12810_ECH.1"
                     /locus_tag="ND450_RS12810"
                     /protein_end="231"
                     /protein_start="4"
                     /score="97.8"
                     /tool="antismash"
                     /translation="YERRDAVAVVTMNRPEYRNAQNSAMTYALDEAFTRAVDDDEVKVI
                     VLAGAGDHFSAGHDIGSPGRDVDVSFERRAVMWWDHVGREGGDLRFAREMEVYLGMCRR
                     WREIPKPTIAMVQGACVAGGLMLAWVCDLIVASEDAFFADPVVRMGIPGVEYFAHPWVL
                     GPRAAKEVLFTGDRFSAQRAYEWGMVSRVVPRASLESSVFELAGRISAMPRFGLALAKK
                     AVNQS"
     gene            12348..13439
                     /locus_tag="ND450_RS12815"
                     /old_locus_tag="ND450_12815"
     CDS             12348..13439
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020419906.1"
                     /locus_tag="ND450_RS12815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12815"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_253326361.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.6e-15, bitscore:
                     56.1, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7.1e-17, bitscore:
                     60.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6.2e-15, bitscore:
                     54.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLSLDAETLSFQAEVRAWLAAHVRSLSSMDTAGGFEEHRAWERS
                     LAAERLSVVSWPAVYGGREASLLQWLVFEEEYHASGAPGRVSQNGIFLLAPTLFAHGTD
                     EQRARILPAMARADEVWAQAWSEPEAGSDLASLRSTATRCDGGWLLRGQKTWSSRAAFA
                     DRAFGLFRTGPGERHRGLTYLLFDLRSDGVTVRPIDQLDGEPGFAEIFLDDVFVPDHDV
                     VGEVGDGWRVAMSTAGNERGLTLRSPGRFTAAASRLVELYRKNPDPALRDRVVDAWIGA
                     QAYRLHTFGALASPLSGPAASVTKVFWSELDVALHETALDLLGEVAPGWRDGWLFSLSG
                     PIYAGTNEIQRNVIAERLLGLPR"
     gene            13436..14251
                     /locus_tag="ND450_RS12820"
                     /old_locus_tag="ND450_12820"
     CDS             13436..14251
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020671791.1"
                     /locus_tag="ND450_RS12820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12820"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_253326362.1"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4e-24, bitscore:
                     84.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMFTLSAEQTDFASVLHDFLGAGGTDLASLGVDEVTDPVDLVVLF
                     EEVGHHAVAGPLVETLAVVPALIGSSGGSSCSVAFPPLLPHALEADRYLLVDGETLREG
                     TPTTELDSVDPTRRLVELTPGPVIATGAPTARAFDLGVLTTSAQLLGLGRALLEMTTEH
                     AKARTQFGTPIGRFQAVKHHLANVLIGLELARPLVFGAAVTMSARDVSAAKVATSDAAW
                     QAARVALQVHGAIGYTAEHGLGRFLLQTRALRTAWGSPSMHRARVLEAL"
     gene            14248..15201
                     /locus_tag="ND450_RS12825"
                     /old_locus_tag="ND450_12825"
     CDS             14248..15201
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637475.1"
                     /locus_tag="ND450_RS12825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12825"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_253326363.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.2e-16, bitscore:
                     60.4, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.9e-21, bitscore:
                     75.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPEQLALRDAVRSLLEKHSDVRAAIETPHGYDKDLWARLTDIGV
                     LPIPERYGGSGATRAETTIALEELGRTLTPSPLLASMLAVEALLAAENEEACERLLPRI
                     ADGTVATLIWPWHGTEYDLDGPARYVLNGDTAEIVLATDGTDLYEVDPGAAREHTPTMD
                     QTRRLATVTPSGATRLGPWDPQIRDIALAALCAEQVGTAARALELTVEYTKTRVQFGRP
                     IGSFQALKHRMADMHVLVETARSAAGAVTDEISAAVAKVYCSEALFEVAAEMVQLHGGI
                     AITWEHDAHLYLKRAHGSGQLFGSPVVHLERLKAKI"
     gene            15205..15777
                     /locus_tag="ND450_RS12830"
                     /old_locus_tag="ND450_12830"
     CDS             15205..15777
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686765.1"
                     /locus_tag="ND450_RS12830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12830"
                     /product="hypothetical protein"
                     /protein_id="WP_253326364.1"
                     /transl_table=11
                     /translation="MDVKTYAVVTDLCARFAGRLDDDALNSVRVHYFAGEPALAEATLL
                     LTLANEDIGITREEHDLIRSASDDPDLAAVRIIDQLPPLAYRFSPTGPADAPDPARADQ
                     VLADEAARYGGRVLRRAWRDPLPGAPDTAKWTYLLHTDDADVLGVYAGLSGRLRVTLEE
                     RWPLEVVHTNVSPYQAAASLAPRIWVA"
     gene            complement(15748..16152)
                     /locus_tag="ND450_RS12835"
                     /old_locus_tag="ND450_12835"
     CDS             complement(15748..16152)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005413733.1"
                     /locus_tag="ND450_RS12835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12835"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_253326365.1"
                     /transl_table=11
                     /translation="MDSAEIGIGEVVRRSGVPASTLRYYEERGLIASVRRQGLTRVFTP
                     AVLEQLALIAVCRTAGFSLDEITLMFSPDGRPSPNREMLAAKADELDATIQKLALMRDD
                     LRHAAACPAPTHLECPRFRSLLGHPDPRGQ"
     gene            16195..16998
                     /locus_tag="ND450_RS12840"
                     /old_locus_tag="ND450_12840"
     CDS             16195..16998
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.5"
                     /locus_tag="ND450_RS12840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12840"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_253326366.1"
                     /transl_table=11
                     /translation="MTSNSAQAELWNAAGQGWANAQDIVGLMLRPFQDVLVDAAARRPR
                     TSVLDVGCGTGAVTRAIAEATGAACVGVDIAESMLEAARAHGKAEYVRADAQVHTFDRT
                     FDLVVSRFGVMFFDDPTAAFANLLKACTGELCFITWRGRDENPFMTTASEVAATLAPDA
                     PAPDLNGPGPHAFADPGHTRAVLADAGWTGIDVEPVDRTCTIPENLLATYLSNLGPISR
                     ALAAVPAEDRPGMLAGVRSAFDGFVHGDEVRVPAACWQVTASAPL"
     gene            complement(16984..17535)
                     /gene="hsaB"
                     /locus_tag="ND450_RS12845"
                     /old_locus_tag="ND450_12845"
     CDS             complement(16984..17535)
                     /EC_number="1.5.1.36"
                     /GO_function="GO:0036382 - flavin reductase (NADH) activity
                     [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="hsaB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657922.1"
                     /locus_tag="ND450_RS12845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12845"
                     /product="3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,
                     17-dione monooxygenase reductase subunit"
                     /protein_id="WP_253326367.1"
                     /transl_table=11
                     /translation="MRSEVTARYRSVLGHFCTGVTVVTGMSPDGPVGFACQAFAALSLD
                     PPLVVFCPQRTSRSWTAMASSGSFCVNVLAEDQREISTVFGRAGADKFAGVSWTPSATG
                     APVLDGALTWVDCQVSVVHDAGDHHMVVGSVVELGPVREAQPLLFYRGRYASHAELDPR
                     GWSGEVLDTLLTWQRQSEWS"
     gene            complement(17535..18437)
                     /gene="hsaC"
                     /gene_synonym="bphC"
                     /locus_tag="ND450_RS12850"
                     /old_locus_tag="ND450_12850"
     CDS             complement(17535..18437)
                     /EC_number="1.13.11.25"
                     /GO_function="GO:0047071 -
                     3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,
                     17-dione 4,5-dioxygenase activity [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="hsaC"
                     /gene_synonym="bphC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983763.1"
                     /locus_tag="ND450_RS12850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12850"
                     /product="iron-dependent extradiol dioxygenase HsaC"
                     /protein_id="WP_253326368.1"
                     /transl_table=11
                     /translation="MGIRSLGYLRIEATDLDRWREFGLKVLGMVEGRGSTPGALYLRMD
                     DFPARLVIVPGEEDRLQASGWEAATEAELEEVAKRLASAGVSYVEGSAEDLAERRVTGL
                     IRFEDPSGNTLEVFHGAALEHRRVVSPYGHRFVTEEQGLGHVVLSTSDDEAALHFYRDV
                     LGFRLRDSMRLPPQFVGRPADGPPAWLRFFGCNPRHHSLAFLPMPTPSGIVHLMVEVEN
                     TDDVGLTLDRALRRKVPMSATLGRHVNDLMLSFYMKTPGGFDVEFGCEGRQVDDEDWIA
                     RESTAVSLWGHDFSVGHQK"
     gene            complement(18437..19246)
                     /gene="hsaD"
                     /gene_synonym="bphD"
                     /locus_tag="ND450_RS12855"
                     /old_locus_tag="ND450_12855"
     CDS             complement(18437..19246)
                     /EC_number="3.7.1.17"
                     /EC_number="3.7.1.8"
                     /GO_function="GO:0102296 -
                     4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),
                     2-diene-4-oate hydrolase activity [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (17-254). E-value:
                     1.1e-34. Score: 112.1. Matches aSDomain:
                     nrpspksdomains_ND450_RS12855_Abhydrolase_1.1"
                     /codon_start=1
                     /gene="hsaD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="bphD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020495449.1"
                     /locus_tag="ND450_RS12855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12855"
                     /product="4,5:9,10-diseco-3-hydroxy-5,9,
                     17-trioxoandrosta-1(10),2-diene-4-oate hydrolase"
                     /protein_id="WP_253326369.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.1e-22, bitscore:
                     79.8, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.3e-24, bitscore: 86.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVRLHYHEAGADNAETLVMLHGGGPGASALSNFRANIPVFAKSF
                     RVLAVDMPGYGQSDKPAEHDQYFSFASRALLDLLDELGVERAHVLGNSLGGGTAVRFAL
                     DHGKRAGRLVLMGPGGLSLNVFSPDPTEGVRKLSAFARTPTREKIEEFLRIMVFDQSLI
                     TEELVDERFEAARQPESLRAMAALGRSFSGPDFEQGMLWREAYKLRQRVLLVWGREDRV
                     NPLDGALLATKLIPRAQLHVFGGCGHWAQLEKFDEFNRLALDFLTEA"
     aSDomain        complement(18485..19195)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ND450_RS12855_Abhydrolase_1.1"
                     /evalue="1.10E-34"
                     /label="ND450_RS12855_Abhydrolase_1.1"
                     /locus_tag="ND450_RS12855"
                     /protein_end="254"
                     /protein_start="17"
                     /score="112.1"
                     /tool="antismash"
                     /translation="LVMLHGGGPGASALSNFRANIPVFAKSFRVLAVDMPGYGQSDKPA
                     EHDQYFSFASRALLDLLDELGVERAHVLGNSLGGGTAVRFALDHGKRAGRLVLMGPGGL
                     SLNVFSPDPTEGVRKLSAFARTPTREKIEEFLRIMVFDQSLITEELVDERFEAARQPES
                     LRAMAALGRSFSGPDFEQGMLWREAYKLRQRVLLVWGREDRVNPLDGALLATKLIPRAQ
                     LHVFGGCGHWAQLEK"
     gene            complement(19257..20423)
                     /gene="hsaA"
                     /locus_tag="ND450_RS12860"
                     /old_locus_tag="ND450_12860"
     CDS             complement(19257..20423)
                     /EC_number="1.14.14.12"
                     /GO_function="GO:0036383 -
                     3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione
                     monooxygenase activity [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="hsaA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020645002.1"
                     /locus_tag="ND450_RS12860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12860"
                     /product="3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,
                     17-dione monooxygenase oxygenase subunit"
                     /protein_id="WP_253326370.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 6.1e-06, bitscore:
                     25.9, seeds: 790, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEEILGKVRELLPTLAERAGEAEELRRVPPETIKTLQETGFFRM
                     LQPARYGGFESHPLDFYTAVRLIASACGSTGWVASVLGVHPWHVGLFDDRAQAEVFGED
                     QDTRISSSYAPTGRAKAVEGGFRFSGRWSFSSGCDHATWVLLGGLVMNDEGKPVDFRTF
                     LLPIADYTINDVWDTVGLRGTGSNDIVVDDVFVPEYRALSMANTARCKCPGQEVNPGPL
                     FRMPYGTIHPYAVTAPIIGMATGAYALHVGATRDRVRAAYLGEKSVDDPFAQVRIATAA
                     ADIDVAWWTLEKDITEEWAHAVADTKIPLDLRLRARRDQVLGSGRALGAIDLLFESAGG
                     KAINAGLPLPRFWRDAHAARVHAGNDPERVLVLYGKNELGIQVRDGLF"
     gene            complement(20420..21430)
                     /gene="dmpG"
                     /locus_tag="ND450_RS12865"
                     /old_locus_tag="ND450_12865"
     CDS             complement(20420..21430)
                     /EC_number="4.1.3.39"
                     /GO_function="GO:0008701 - 4-hydroxy-2-oxovalerate aldolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dmpG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020486785.1"
                     /locus_tag="ND450_RS12865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12865"
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="WP_253326371.1"
                     /sec_met_domain="HMGL-like (E-value: 2.1e-51, bitscore:
                     174.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLRLTDTSLRDGSHHKRHQFTADDVRSIVAALDGAGVPVIEVTH
                     GDGLGGSSFNYGFSHTPEQELIKIAAETATQARIAVLMLPGVGVKDDILISQDNGASIV
                     RIATHCTEADVSVQHFRLARERGLETVGFLMMAHSQPPEALAKQARIMADAGCQCVYVV
                     DSAGALVLEQVSERVEALVAELGKDAQVGFHGHENLGLSVANSVAAARAGAEQIDGSVR
                     GFGAGAGNTPLEAFVGVCDKLGFETGVDFFKIVDAAEDVVRPVMPDECLLDRMALMMGY
                     AGVYSSFLKHAYTQAQRYGVSGAQILVRAGERKLVGGQEDQLIDIALELSRENVR"
     gene            complement(21396..22274)
                     /locus_tag="ND450_RS12870"
                     /old_locus_tag="ND450_12870"
     CDS             complement(21396..22274)
                     /EC_number="1.2.1.10"
                     /GO_function="GO:0008774 - acetaldehyde dehydrogenase
                     (acetylating) activity [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019807469.1"
                     /locus_tag="ND450_RS12870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12870"
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="WP_253326372.1"
                     /transl_table=11
                     /translation="MKAAIVGSGNIGTDLLYKLLRSDALEPRWMVGVDPASEGLRRAAD
                     LGLEVSVDGAEWLLRQDELPDVVFEATSAAVHRANAPRYAEAGVRAIDLTPAAVGPYVV
                     PPVNLGEHADAPNINLITCGGQATIPMVHAVSRVVPVSYAEIVASVASVSAGPGTRANI
                     DEFTRTTSRGIEEIGGASRGKAIIVLNPADPPMIMRDTIFCAIPEDTDPDPITDSIARM
                     ETDIRSYVPGFRLLREPQYDAGRVAIFVEVAGAGDFLPEYAGNLDIMTAAATKVGEEIA
                     NAAAAHRHVTA"
     misc_feature    complement(22263..22272)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(22284..23054)
                     /locus_tag="ND450_RS12875"
                     /old_locus_tag="ND450_12875"
     CDS             complement(22284..23054)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020495035.1"
                     /locus_tag="ND450_RS12875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12875"
                     /product="2-keto-4-pentenoate hydratase"
                     /protein_id="WP_089921233.1"
                     /transl_table=11
                     /translation="MLTIQSREAAAELLRTAERDRVPIKPLVELYPEIDVVDAYEIQLL
                     NVRHRNRDVIGHKVGLSSLAMQQMMGVDEPDYGHLLDDMQLAGTADASAYLYPRVEVEI
                     AFLLARDLPGEGCTVQDVLEATEFVVPAIELIDSRIENWRIGLQDTIADNASSAGFMLG
                     SERVRPSELDIGAVAATLRRNGEVVAEGRGDAVLGDPAIAVAWLAAKVAGFGVRLLAGD
                     IVLPGSCTRAIDARPGDEFHAEFAGLGSVDLKFE"
     gene            complement(23048..24505)
                     /locus_tag="ND450_RS12880"
                     /old_locus_tag="ND450_12880"
     CDS             complement(23048..24505)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075397.1"
                     /locus_tag="ND450_RS12880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12880"
                     /product="FAD-binding protein"
                     /protein_id="WP_253326373.1"
                     /sec_met_domain="DAO (E-value: 1.4e-13, bitscore: 50.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTADVVVIGFGAAGACAAVEAAASGASVVVLDRFGGGGATALS
                     GGVVYAGGGTRQQVEAGVPDSVDAMYSYLRHEVRDAVSPETLRRFCEDSAKMLAWLEDQ
                     GVPFDARLSPFKTSYPTDDYYLYLSGSEDAWPDPAPRGHRTRAKGTSGREFFTRLAEAT
                     RRAGVRIMPQTRAVELVQENGRVTGVRCRALTGLPRVLHSALSKAGAKPWLYYPPLGRR
                     LFGLAARLERFSRPLVITAGQGVVIAAGGFIADRALVHEHAPAHRGGLALGTPGDDGGG
                     IRLGVAAGGRTARMDRISVWRFVTPPSALQRGVLVDSAGQRFGDARLYGAANGSEIVAR
                     GGKAWLLVDDEILQVARAQVRTQTAPFQRWQVRHLLGRGLVTAPTIEEVARKAGIATPE
                     PFGTPPYSLINVSVRAGFGYPCPMLTLGGLVVDEDTGQVQGVPGLYAAGRSAVGVCSES
                     YVSGLALADCVFSGRRAGSHVAKEARC"
     misc_feature    complement(24600..24620)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.39"
                     /tool="antismash"
     gene            24638..26209
                     /locus_tag="ND450_RS12885"
                     /old_locus_tag="ND450_12885"
     CDS             24638..26209
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003092799.1"
                     /locus_tag="ND450_RS12885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12885"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_253326374.1"
                     /sec_met_domain="DAO (E-value: 6.7e-13, bitscore: 48.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYDVIVVGSGAAGMTAALCTAQHGLRTLIIEKAAHYGGSTARSGG
                     GIWVPNNAVVAASGVSDSPERAGTYLGHIAPEVPAELRQAFLDAGPAMLAFVRAHTPLE
                     FRWVRDYSDYYPEAPGGQPRGRSVEPLPFKTKLLGEEVEDLEPPYVPTPAGIVITQTDY
                     RWLTLIGRHPRGIATAAKVFVRRFLPGRRLTMGQALTAGLRAGLKALNVEIRLNTAMTD
                     LHHENGRVAGVLVGEKLILAKHVVLACGGFEHNEQMRKQHQNIGTEWTVGAKANTGDGI
                     EAGQRAGAAVGLMDDAWWGPSVPLPRGPFFLLAERSLPGCVLVDKTGRRFVNESAPYID
                     VVNAMTGDTWLVFDHSYRGRYPFCGIPPRRPLPRRWKDSVLTAPSLEELAQQADLPELV
                     DTVRRFNTLSVAGEDTDFHRGDSAYDRYYGDPRTKPNPNLAPLTTGPFYAVRIVPGDLG
                     TKGGLRTDASARVLREDGSVIEGLYAAGNTSASVMGHTYAGAGATLGPAMTFGYLAGLD
                     ITGGER"
     gene            26206..27342
                     /locus_tag="ND450_RS12890"
                     /old_locus_tag="ND450_12890"
     CDS             26206..27342
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020644999.1"
                     /locus_tag="ND450_RS12890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12890"
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="WP_253326375.1"
                     /transl_table=11
                     /translation="MTQDGVRTIDAGAPPARFARGWHCLGLASHFRDGKPHAVEAFGTK
                     LVVFASEDGEINVLDGYCRHMGGDLTQGTVKGNTLACPFHDWRWAGNGRCVDIPYAKRV
                     PLRARTRSWITLEENKQLFVWNDPQGNPPPEHVTIPRIDAAFSTEWSNWTWDSVVIDNA
                     NCREIIDNVVDMAHFFYIHFAFPIYFKNVMEGHVASQYLTTRGRPDVAMGSNYTGDVEV
                     RSEAAYYGPSYMIDYLWNDYKGLEIETVLINCHYPISPTSFKLQWGAIVKKLPGVDDEH
                     ADKIAAKFARGIGVGFLQDVEIWQNKSRVDNPLLCEEDGPVYQLRRWYEQFYVDVEDVS
                     DDMVRRFEFEVDTSRAIEVWEKEVAENLARQQPQEQAT"
     gene            27339..27578
                     /locus_tag="ND450_RS12895"
                     /old_locus_tag="ND450_12895"
     CDS             27339..27578
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003092805.1"
                     /locus_tag="ND450_RS12895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12895"
                     /product="hypothetical protein"
                     /protein_id="WP_371927698.1"
                     /transl_table=11
                     /translation="MSERDEFLKGGMVPVGCDCGNRVLVKKNSPQHTSVQWLSDTRNCP
                     ELCGARAALVPTCLRLRDSIEKAVREGTLEVADG"
     gene            27571..28533
                     /locus_tag="ND450_RS12900"
                     /old_locus_tag="ND450_12900"
     CDS             27571..28533
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637494.1"
                     /locus_tag="ND450_RS12900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12900"
                     /product="ferredoxin--NADP reductase"
                     /protein_id="WP_253326376.1"
                     /transl_table=11
                     /translation="MAEVHRLRVDAVIEETADARSFVLSGADFSPRPGQFLTVRAGEVA
                     RCYSLSSAPGEPLKITVKRTPDGYGSLWMCSELRAGMELDVLAPAGVFTPSSLDGSLLA
                     FAAGSGITPVMSIIRAVLHGGSGQVFLFYANRDESSVIFAGELSELARAHPDRLTVVHW
                     LESVQGLPHGLRAFVRPCDEAFVCGPVPFMEAARKALHDVPVVHVEKFVSLSSDPFGAE
                     EPIADGRPDAVVEVSLDGERHRFPWPARTKLLDLLLERGLDAPYSCREGACSACACRLV
                     EGEVKMLNNDVLDSEDIAEGIVLACQSVPVTDNVKITYE"
     gene            28544..29377
                     /locus_tag="ND450_RS12905"
                     /old_locus_tag="ND450_12905"
     CDS             28544..29377
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033673.1"
                     /locus_tag="ND450_RS12905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12905"
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="WP_253326377.1"
                     /transl_table=11
                     /translation="MPIDPSVAVGAELPEVKFSWTESDVLLYHLALGATELRYVYERGL
                     RVLPTFGVVAPRFHETAAPVVSFPGVDIDLARVLHGTQEIAVHSPLPASGEAVLRTRIS
                     DVWDKGKAAVIVQEATAVAPDGTALFTTRSSIFARGEGGFGGDRGPSGRVEVPAHEPDF
                     LIETATLPQQAYLYRLCGDRNPLHADPEFASRAGFDAPILHGLCTYGVVCKAVIDALLD
                     GPEQVSSFSAKFAGVVFPGETLTTRVWRDGTRLVVSTSAGDRPVLSDAVLQLAED"
     gene            complement(29357..30499)
                     /locus_tag="ND450_RS12910"
                     /old_locus_tag="ND450_12910"
     CDS             complement(29357..30499)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019807664.1"
                     /locus_tag="ND450_RS12910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12910"
                     /product="lipid-transfer protein"
                     /protein_id="WP_253326378.1"
                     /transl_table=11
                     /translation="MNAAIVGIGATDFSKDSGRSELQLAAEAVRAALEDAGLTPSDVDG
                     LVSFTMDTNAEIAVARELGIPELTFFSRVHYGGGAACATVQQAAMAVETGAAEVVVCYR
                     AFNERSGHRFGQVQTAAAANIDNSWSYPMGLGTPAAMVAMFAQRYMHEYGATSEDFGRI
                     AVIDRKHAATNPHAWFHERPITLDDHQSSRWIAEPLRLLDCCQESDGGVALVVTSAQRA
                     KDLPNKPAHVKAATQGSGADQFTMTSYYRDDLTRLPEMGVVARGLWERSGITRSDVDVA
                     VLYDHFTPFVLVQLEELRFCGRGEAKDFIRTGALELDGDLPLNPHGGQLGEAYLHGMNG
                     IAEGVRQIRGTAVNQVANVGHVLVTAGTGVPTSGLILGQL"
     gene            complement(30496..30879)
                     /locus_tag="ND450_RS12915"
                     /old_locus_tag="ND450_12915"
     CDS             complement(30496..30879)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657909.1"
                     /locus_tag="ND450_RS12915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_12915"
                     /product="MaoC family dehydratase"
                     /protein_id="WP_253326379.1"
                     /transl_table=11
                     /translation="MRIGDSLPEWHVEATPTFVISTALATRDFQDVHHDRDLAVQRGSK
                     DIFINILTTTGLVQRYVTDWAGPQALVRQVNIRLGAPCFAYDTLKFFGQVVGREQQDLT
                     IEVVGRTAHGDHVTGTVKIEVPA"
ORIGIN
        1 ggcctgcacg ccgccgagct cctcggtgcg gcacaacgag gtcttcttga caggacaggc
       61 ctcgatccgt ccaccgtcga acaggtcatc ggcggctgcg tcacccaggc gggcgaacag
      121 tcgagcaaca tcacccggac ggcctggctg cacgcgggcc tgccgcagac caccggcgcc
      181 accacgatcg acgcccagtg cggctcggcc cagcagtcca cgcacctcgt cgccggcctg
      241 atcgccgcgg gcgcgatcga cgccggcatc gcgtgcggcg tggaggcgat gagccgcgtc
      301 ccgctgcgca gcaacatcgg cgagaccggc atgccgcgcc ccgagtcgtg gacgatcgac
      361 ctgcccaacc agttcgtggc agccgaacgc gtcgccgccc gccgcggcat cggacgcgag
      421 gaggtggacc gcttcggcgt ccagtcgcag aaccgggcac gggcggcgtg ggcggcgggc
      481 aggttcaccg ccgaggtcgt gccggtgaag gtcggggagg acctggtgga caccgaccag
      541 ggactccgcg agacgtcact ggaggcactc gcgacgctga agccggtcgt gccggacggt
      601 gtgcacaccg cgggcacgtc gtcgcagatc tccgacggcg cctcggccgt gatggtcgtg
      661 gacgaggagt tcgcacgagc gcacggcctg aaaccccgcg cacggatcgt gacgcagtgc
      721 ctggtcggct cggacccgta ctaccacctg gacggcccgg tcgacgccac cgcgcggctg
      781 ctgaagcgca gcggcatgaa gatggcggac atcgacctgt tcgaggtcaa cgaggcgttc
      841 gcgtccgtcg tgctgtcgtg ggcggcggtg caccggccga acctcgaccg ggtcaacgtc
      901 aacggcggcg ccatcgccct cggccatcct gtgggcagca ccggcacgcg gctcatcacc
      961 acggcgttgc acgagttgga gcggcgggac gcgagtacgg cgttgatcac gatgtgcgcg
     1021 ggtggggcca tggcgtccgg gacgatcatc gaacggatct gaggtcggcc gccgggtacg
     1081 gggttcgcct gctctcgtgc tggaagcgga ggagtccact cacaccccgg tccacctcca
     1141 acggcggttg gcacgtcgtg cagggctctg agcacggcaa ccaggacgac acgacgccgg
     1201 cgccgcagtc cctcggtgcg ccgctccggc gccggatctc cgcggtcgac agccgctcca
     1261 gcctccaggg ccacgtgtgc cgaggtgcgg cgaacggtcg gtgatccatc aacggtgtgc
     1321 gtcgcggtcg cgcaccagca gtcggtctcc cacagctcac gtcagatcga cagctgctct
     1381 cgtcgcctca tcgtcgtcgg ctcgcaggtg agttcaacgg gacacggcgg cgtgtgcggc
     1441 gagacgggtc acatgatcga acctactcgg ccccgtagac cggcaccggg tggtcgtccg
     1501 cgaccagctt gcgcaccacc gcccccaact cctccaccga ccagcgcgcg cccttgtcga
     1561 cctccggccc gcgccgccac ccgtgcacca cgcacacgcg cccgccgtcg acctcgaaca
     1621 tccgccccgt cacgtccccg gcctcctcgc tgccgagcca cacgaccagc ggcgagatgt
     1681 tctccggcgc catcgcgtcg aagccgtcct ccggtggcgc catcatgtcc gcgaacgtcg
     1741 cctcggtcat gcgggtgcgg gcggccgggg cgatcgcgtt gaccgtgacg ccgtagcggg
     1801 ccagttcggc ggccgcgacc agcgtcatcg aggcgatgcc cgccttggcc gccgagtagt
     1861 tcgcctggcc aacgctgccg aagaggcccg cgccggacga cgtgttgatc acgcggcccg
     1921 acaccgcgcc gccggccttc gcgactccgc gccagtgggc ggcggcgtgg tgcagggtgg
     1981 cgaagtggcc cttgaggtgg acgcggacga cctcgtccca ctcgtcctcg ctgcagccga
     2041 cgaccatgcg gtcgcgcacg atgccggcgt tgttgaccag cacgtcgagg ccgccgaacg
     2101 aggacaccgc ggtctcgacc aaccgccgcg cgcccgccca ggtgccgacg tcgtcggtgt
     2161 tgacgacggc cctcggaccg atctggtccg ccacctcgcc cgctacggcc gcggacaggt
     2221 cgttcaccac gaccctgcac ccggcggcgc cgaacgccag cgcgtgggcc cggccgatgc
     2281 cccggcccgc tcccgtcacg atcacgaccc ggctcatgcg gtacccccat cggcagcggt
     2341 caggaacgcg ggtgcctctc ccccgccgtg aacgaccaag gtcgcgccgc tcacgtagga
     2401 cgccagcggt gacgccagga acacggcgca cgcgccgacc tcgtccggtg acgcgagacg
     2461 ccccaacgga acagtgcgag ccacggcctc gatcccggcc tcggagccgt agtgcaggtg
     2521 cgactgctcc gtgcgcacca tgcccacggc cagcgcgttg acccgcacct tcggcgccca
     2581 ctcgacggcc agcgacgacg tcaggctgtc cagaccggcc ttcgcggcgc cgtaggcggc
     2641 ggtaccaggt gagggacgcc gtccgctcac gctgctcacg ttgacgatcg agccggagcc
     2701 ttgctcctgc atgacctcgt tggccgcctg ggacaccagc aggggcgcca gcaggttcag
     2761 ctcgacgatc ttcgagtgga agcgcggcga ggccttgtcc gccaaagcga acggcgcccc
     2821 tcccgcgttg ttcaccacca cgtccacccg accgtgctcg gcgacgatcc cggacaccag
     2881 ctcggacacc tggtcggcgt cccgcacgtc gcacggcacg aacgacgcgc cgtcgacctc
     2941 cgcggggcgt cgcgcacatg tcacgacggt cgcgcccgcg gacaggaacg cgcgggtgat
     3001 gccgagaccg acaccccgca cgcctcccgt caccaggacc actgctccgt gaaggtccag
     3061 ttccaccagc acctaccccg gtcgcttcgg cactgctaaa ttaccaagca atcgcttggt
     3121 tcggaaggcg gctccatggg aatctccagc agccacaccg aaaacggcat catcgaggtc
     3181 accgtcgact acccgccggt caacgccatc ccgtcacagg gctggttcga gctggccagg
     3241 gccgtgacgg ccgcgggcga ggacccggac gcgcgggtgg tggtcctcag ggccgagaac
     3301 cgcggtttct gcgcgggcgt cgacctcaag gagatccagc gcgccgaggg ctacaacgcg
     3361 ctcgtggcgg cgaaccgggg ctgcgccaag gcgttcgcgg ccgtgtacga ctgcgaggtg
     3421 ccggtgatcg ccgcggtgaa cgggttctgc ctcggcggcg gtgtcgggct ggtcggcaac
     3481 gcggacatca tcgtcgcctc ggacgacgcc acgttcggcc tgcccgaggt cgatcgcggg
     3541 gccctcggcg cggcgacgca cctggccagg ctcgtgccgc agcacctcat gcggacgctg
     3601 tactacaccg cgcgcaacgt cagcgcgcag acgttgcacc accacgggag cgtcgtcgag
     3661 gtcgtgccac gcgcacagct ggacgaggcg gcccgcgaga tcgccggaga gatcgcgaag
     3721 aaggacacgt cggtgatccg cgcggccaag gaggccatca acggcatcga cccgcagcgc
     3781 gtgcaccaga gctaccgctt cgagcagggc ttcaccttcg agctcaacct caccggtgtg
     3841 tcggaccacg cccggcaggc cttcctggac ggacaccatg cgcgacaagc gaatgacggc
     3901 tgacgaggtc gtcggcacca tcaaggacgg gatgaccgtc ggcatcggcg gctggggctc
     3961 gcggcgcaag ccgatgacgc tggtcaaagc gttgctgaag agtccagcca cagacctgac
     4021 cgtggtcacg tacggcggcc cggacgccgg gttgctgtgc gcggcgggca aggtccgcaa
     4081 gctcgtctac gggttcgtct cgctcgactc gatcccgtac gacccgtggt tcaaacgggc
     4141 gcgcgagacc ggcgcgatcg aggtcctcga actggacgag ggcatgttcc agacggggct
     4201 gcgggccgcg gcgcaccggt tgccgttcct gccgatcagg gcgggcctcg gctcggacgt
     4261 gctgaagtac gcgccggagc tcaagaccgt gcggtcgccg tacgacgacg gcgaggaact
     4321 ggtcgcgatg ccggcgttga agctcgacgt cgccttggtc cacctgaacc gcgccgacaa
     4381 gcacggcaac gcccagtacc tcgggcccga cccgtacttc gacgacctgt tctgcctggc
     4441 cgcggaccgg cgttacgtct cgtgcgagca ggtcgtggag tcgttcgacg ggccgccgca
     4501 gacgttgctg ctcaaccgga tgatggtcga cggcgtggtg caggcgcccg gtggagcggg
     4561 gttcacgagc tgcgtgcccg actacggccg cgacgaggcc ctccagcgcg agtacgccaa
     4621 cgccgccacg gacctggagc agtggccgga cttctacgag aggttcctcg aatgagcgac
     4681 atcacgcgag cagaggtctg cgtcgccgcg tgcgccgacc tgttcctcgg cgccggtgag
     4741 acgctcgcca gcccgatggg cctcatcccg tcgctcgggg cgaaactggc caggctgacg
     4801 gacgaacccg acctgctgct gagcgacggc gaggcgttcc tgctcacgcc cgagtccact
     4861 gtggagggct ggctgccgta ccggaaggtg ttcgacgtcg tcgcgcacgg ccgccggcac
     4921 gtcgtgatgg gcgcgaacca ggtcgaccgg ttcggcaacc agaacatctc cgccatcggc
     4981 gaccacgcga ggcccacccg gcaactcctg ggcttccgcg gcgcaccggg caacaccgtc
     5041 aaccaccgca ccagctactg ggtgcctcgg cacagccccc gtgtgctggt cgaggccgtg
     5101 gacgtggtgt ccggtgtcgg ctacgaccgc gcggccgggc cgttccacga cgtccaccgc
     5161 gtggtcacga acctcgccgt gctcgacttc ggcacccccg accactcgat gcgcatcgtc
     5221 tccgtgcacc ccggcgtatc cgtcgacgag gtgcagaagc agacgtcgtt cccgctcgtc
     5281 gccgaggacg tcggcgagac ccgcctgccg accggcgggg aactggacct gatcaggacg
     5341 aggctcgacc cgcagggcaa gcgggacaag gaggtcccgt catgaggacg gccctgaccg
     5401 agctggtcgg cgtgcggcac ccggtcgtgc agaccggcat ggggtgggtc gcgggcccgc
     5461 ggctggtctc cgcgaccgcc gaggccggtg ggctcggcat cctggcctcc gcgaccatga
     5521 cctaccccga gctcgaagcc gccatcaagg agacccgctc ccgcacgtcg gcgcccttcg
     5581 gcgtgaacct cagagccgac gcgcacgacg ccccggaacg gatcgacctg ctgatccgcg
     5641 aacaggtgaa ggtcgcctcc ttcgcgctgg ccccgaaacc cgacatgatc gcgaagctga
     5701 acgacgccgg ggtcgtggtg atcccgtcga tcggtgcggc gaggcacgcc gagaaggtcg
     5761 cgcagtgggg cgcgcacgcg gtgatcgtgc agggcggcga gggcggcggg cacaccggcg
     5821 gtgtcgcgac gacgttgctg ctcccgagcg tgctggacgc cgtcgacatc ccggtggtcg
     5881 cggccggcgg cttcttcgac ggccgcgggc tcgcggcggc gctcgcgtac ggcgcggccg
     5941 gcatcgcgat gggcacgagg ttcctgctca cccgggaaag caccgttccg gacgcggtca
     6001 aacacgccta cctccaccgg gatctcaacg gcacggtcgt gaccacccgc gtcgacggac
     6061 tcccgcaccg cgtcctgcgc tcggacctgg tcgagcacct cgagaggtcc ggccggatca
     6121 gcggcctggc gcgagccgtc gcgaacgcgg ccaggttccg gcagcacacc gggctgacgt
     6181 ggcgcgcgat gatccgcgag ggcctggcca tgaagcacgg cagagacctc acctggtcgc
     6241 aggtcgtcat ggcggcgaac acgccgatgc tgctgcgggc aggcctcgtc gagggccgca
     6301 ccgacgccgg cgtgctcgcg tccggccagg tcgccggact gctcggcgac ctgccgacgt
     6361 gcgcggacct ggtcgagggg atcgtgaagg acgccgaggc ggcgatcgac cggctcagag
     6421 acgttcgatg atcgtcacgt tcgcctgacc accgccctcg cacatcgtct gcagcccgta
     6481 ccggccgccc gtccgctcca gctcgtgcag caaggtggtg aacagcttcg tgccggtcgc
     6541 gccgatcggg tgacccagcg cgagcgctcc cccgttcacg ttcacgcgcc cgagatcgac
     6601 cttcagctcc ttggcccacg ccatggccac cgacgcgaac gcctcgttga tctcgaacag
     6661 gtcgatgtcc gaaatggaca tcccggcgcg ctccagcgcg tacttcgtcg cccggatcgg
     6721 cgcggtgagc atgtagatcg ggtccgagcc gcgggcggac atgtggtgca cgcgggctcg
     6781 tggcgtcagc ttgtgctcgc gcacggcctg ttccgacacg accagcaccg ccgaggcgcc
     6841 gtcggagatc tgcgacgaca acgccgccgt cgtccgcccg ccgggacgca acggctggag
     6901 cttcgccatc ttctcggcgc tggtgtccgg acgtgggcac tcgtcggccg cgatgccgtt
     6961 gaccggcgcg atctcgcggt cgaaccggcc ctccttgatc gcggtgatcg cccgcaggtg
     7021 gctctgcagc gcgaagtcct ccatctcgcg ccgcgacagg tcccaccgga cggcgatcag
     7081 gtcggccgcc cggaactggc tgacctcctc gtcgccgtag cggtgctgcc agccctcgca
     7141 gccctcgaac gggctgccca cctgcgaacc ggccgtcatc gccgagccga tcggcacctg
     7201 cgacatgttc tgcacaccgc ccgcgacgac gacgtcggcc gtgccgctca tcaccgcctg
     7261 cgccgcgaag tgcagcgcct gctggctcga cccgcactgg cggtcgaccg tcacgcccgg
     7321 cacctgctcc gggaacccgg cggccagcca ggacgtccgc gcgatgtcgc ccgcctgcgg
     7381 gccgacggtg tccacgcaac cgaagatcac gtcgtccacg tccgtcgggt cgacgtccac
     7441 gcggttgagc agcgccgtga tcacgtgcgc gccgagatct gccgggtgga cgtggctcag
     7501 ctcgccacca cgcctgcccg ccggggtccg cacagcctcg atgatgtacg cctcggccac
     7561 gaggggccct ccttcaagct atgtcttgga gttcttccgg cggcccgtgg cgatgccgtc
     7621 gagcaggatc gcgaggtact ggtcggccac cgcctccgcg cgcagttcgc cgtccggccg
     7681 gtaccagcgc acggccaccc acaccgtgtc gcggatgaac cggtacgcca cgtccacgtc
     7741 gaggtcggcg cggaacacgc ccgcgctgat cccctcctcc agcagcaccg tccacagctt
     7801 gcggaactcc acgctgcggt cgtcgatgta ggagaaccgc tccaggccgg tgaggtgctt
     7861 ggcctcgttc tggtagatcg cgacggcggc gtgccgggtg tcgatcgact cgaacgacgc
     7921 cacgaccagg gccttcaacg tctgcttggg gccgagcccg gcgtcgacga tctcccggta
     7981 ccgcgtgaac agctcgtcca ggaacgtccg caggatctcg tccaccatcg actccttgga
     8041 gtcgaagtgg tggtagaggc tgccggacag gatccccgcc gcgtccgcga tgtcgcgcac
     8101 ggtcgtctgc ccgtacccgc gttcggcgaa catcctcgcc gccaacgcga gcagttcctg
     8161 ccttctggtg ctcacggtct taccttcctc acgggtgctg actgctcacc gagacgacct
     8221 cgcccgtcag gtaggacgag tagtcgctgg cgaggaacac gatcacattc gcgacctccc
     8281 acggctcggc ggcgcgcccg aaagcctccc gggacgccag ttccgtcagc aactcctcac
     8341 tggtgacctt ggtcaagaac gggtgcgccg ccaagctcgg cgcgaccgcg ttcacccgga
     8401 tgccgtgctc ggcgacgtcc atcgcggcgc acctcgtcag cgccatgacg cccgctttcg
     8461 ctgcggcgta atgggcttga cccttctggg cgcgccagcc gatcacactg gagttgttaa
     8521 cgacgacacc gcttcgttgg acgaccattc ggcgtaacgc ggccctggtg cagcggaagg
     8581 tgccgttcag cgtgacgtcg aggactttcg cccactcgtc gtcggtcatg tccaggacgg
     8641 acttctcgcc gcccagaccg gcgttgttga ccatcacgtc gatgcggccg tagcgctcga
     8701 ccgtctcgtc gaccaggtgc tgcacctgct gctcgtcggt gacgtcgcac gggacggcgt
     8761 gggcggtgcc gagagccttg tgcgtctcct tgaggcggcg ctcgtgccag tcgctgatga
     8821 ccaccgtggc gccctcttcg aggcacctcc tggcggtcgc gctgccgatg ccggtgcccg
     8881 ctgcggccgt gaccacgacg accttgtccc ggagcaggtc gtggccggtc atcgcggcag
     8941 tcccaggacg cggtgggcga tgatctcgcg ctggatctcg tccgagccgc cgtagatcgt
     9001 ctccgcgcgg ctgaacagga acaggcgctg ccactcgttg tcgtcgatca tcgactcggg
     9061 cccgagcgag tccatcgcga gctcgccgag ccggcggtgc cagctccccc agaacagctt
     9121 cagcacggac gcctccgggc ccggttcgtc gttcagggtc ctcatggtgt gcgaacgcat
     9181 cacgtgcagt tcgagccacg ccctggtgag gcgttcgtcg tccgggttcg tggccatgat
     9241 cgcgtcgagc tggcggcgga agcccacctg gtggccgagc atcgccgtgc cgcgttcgaa
     9301 gccgagggtg gccatggcga tcttccagcc ctcaccgggt tcgcccacga cgttggtgcg
     9361 cgccgtcacc gcttcgtcga agaagacctc gttgaactcc gacgtgccgg tgagctggcg
     9421 gatcggccgg acctcgacgc cgggctggtt catcggcacg agcaggtacg agaggccgtg
     9481 gtgccgttgc gaaccgggtt cggtgcggca cagcacgaag atccagtccg agtagtgcgc
     9541 gttcgacgtc cagatcttct ggccgttgat cacccaccgg tcgccgtcca gggtggccct
     9601 ggtctgcacg gacgcgaggt ccgagccggc gccgggttcg gagtagccct ggcaccacag
     9661 ctcgtcgagc gcgcggatct tcggcaggaa gcgcgccttc tgctccggtg tgccgaaggc
     9721 gaggagcgtc gggccgagca ggccctcgcc cacgatgtcg accttcgccg gcgcgtcggc
     9781 ctccgcgtac tcctcgtgga agaccacctg ctcctccacg ctgcgatcgc cgggccagcc
     9841 gaggcacgtc cacccgctcc gcgcgaggtg gcggtgccac cgcagcctgc cctcgaacgc
     9901 ctcgtgctcg cgacccggtc cacccaggcc gcgcagctca gcgaactcac cgacgaggtt
     9961 ggcggacaac cattcccgca cctcgcgccg gaaggactcc atgggccata ctctaaccta
    10021 ccaagcactt gctttggagg gcgttgtggc cgtagatcca agcaggcaaa cggtttcagc
    10081 cgtgctcgac cgcgctgctg cttcgtacat cgacgcggag gcgttggtgg acggggaggt
    10141 ccgcctcagc tggctcgagc tccgctcggc ggtgctcgac gcggcgcgcg ccctcgtggg
    10201 gacgggcgtc cgtccgggtg atcgggtggc cctgtgcgcg cccaactcgg cgcggtgggt
    10261 ggtcgcggcg ctcggggcgt tgcgggcggg cgccgcactc gtgccgatca acacccggtt
    10321 caccgcgacg gagacgctgg acgtgctccg ccgcagtgcc gctcgggtgc tggtcgtgga
    10381 gggcgagttc ctcggccgcg accgggaggc ggaactccgt gcgctgtccc cggaactgcc
    10441 cgcggtggtg cgactgccgg ccacgtgggt tccggccgac gtcgatctgc ccgagctttc
    10501 cggggaagcg ttgtgcgacg tcatgttcac ctccggcacg acggggcgca gcaagggggc
    10561 gatgagcgcg caccggcagt cgatcggggt ggccgaggcc tgggcggcct gtggcgagct
    10621 gacctccgcg gaccggtacc tggtcgtcaa ccccttcttc cacaccttcg ggtacaaggc
    10681 ggggatcctc gcctgcctgc tcaccggcgc gacgatcgtg ccgcagccgg tgttcgacgt
    10741 cgtcgagacg atgcggctgg tcgagcggga gcggatcacc gtgctgccgg ggccgccgac
    10801 gatcttccag acgctcctcg accacccgga ccgcggctcg ttcgacctgt cgagcctgcg
    10861 gctcgccgtc accggcgccg cggtcgttcc ggtggtgctg atcgaacgga tgcgggcgga
    10921 gctctcgctg accgtgctca ccgcgtacgg gctgaccgag gcagtggtcg ccacgatgtg
    10981 ccgtccgggt gactcgccgg agacggtcgc ggacacctgc ggggcgccga tggcggggtt
    11041 cgaactgcgg ctgggcgcac gggacgaggt gctgttgcgc ggccccaacg tgatgctcgg
    11101 gtacctcgac gacccggtcg ccaccgccga ggccgtcgat gccgacggct ggttgcacac
    11161 cggtgacgtc ggacggctgg actcccgcgg ctacctgtcc atcaccgacc ggctcaagga
    11221 catgtacatc tgcggcgggt tcaacgtcta ccccgccgag gtcgagcagg cactggcccg
    11281 gttgcccggg gtcgccgagg tggccgtggt cggcagggcg gatgcgcggc tcggcgaggt
    11341 ggggctcgcc ttcgtcgtga cggcgccggg gtcctcgctc agcgagtccg acgtgatcgc
    11401 gttctgccgc gaacggctgg ccaactacaa ggtgccgcgc gcggtcgagt tcgtgccggc
    11461 actcccccgc aacgcgatgg gcaaggtcct caaaacccaa ctgcgcaagg agaacgcgtg
    11521 acagtctcgt atgagcggcg ggacgcggtc gccgtcgtga ccatgaaccg ccccgagtac
    11581 cgcaacgcgc agaactcggc gatgacctac gcgttggacg aggccttcac ccgcgcggtc
    11641 gacgacgacg aggtcaaggt gatcgtcctg gcgggcgccg gcgaccactt ctccgcgggc
    11701 cacgacatcg gttctcccgg ccgtgacgtc gacgtctcct tcgagcgcag ggccgtgatg
    11761 tggtgggacc acgtcggccg cgagggcggt gacctccggt tcgcccgcga gatggaggtc
    11821 tacctcggca tgtgccggcg gtggcgggag atcccgaagc cgacgatcgc gatggtgcag
    11881 ggcgcgtgcg tggccggcgg cctgatgctc gcctgggtgt gcgacctgat cgtcgcctcc
    11941 gaggacgcgt tcttcgccga tcccgtggtg cgcatgggga tcccgggcgt cgagtacttc
    12001 gcccacccgt gggtgctcgg gccgcgcgcc gccaaggagg tgctcttcac cggcgaccgg
    12061 ttctccgccc agcgcgccta cgagtggggc atggtctcgc gcgtcgtgcc gcgtgcctcg
    12121 ctggagtcgt ccgtgttcga gctggccggt cggatctcgg cgatgccgcg gttcgggctg
    12181 gcgctcgcca agaaggcggt caaccagtcc gaggacctga tgggcctgcg cgccggcatg
    12241 gactcggtgt tcgggctgca ccacttcgcg cacgcgcaca acgccgaggt gagctccgac
    12301 gcgctggcgg ggatggacgc ccgcgcgatg aagaaggcct ccggctgatg gacctctcgt
    12361 tggatgcgga gaccctgtcg ttccaggccg aggtgcgcgc ctggctggcc gcacacgtgc
    12421 gttcactgtc ctcaatggac accgccgggg gcttcgagga acaccgcgct tgggaacgtt
    12481 cgctggccgc cgagcggctg tcggtggtgt cgtggcccgc ggtctacggc ggccgggagg
    12541 cctcgctgct gcagtggctg gtgttcgagg aggagtacca cgcctcgggc gcgccgggac
    12601 gcgtgtcgca gaacggcatc ttcctgctgg cgccgacgtt gttcgcgcac ggcaccgacg
    12661 agcaacgcgc gcggatcctt cccgcgatgg cccgcgccga cgaggtgtgg gcgcaggcct
    12721 ggtcggaacc cgaggcgggg tcggacctgg cgtcgttgcg cagcacggcc acccgctgcg
    12781 acggcggctg gctgctgcgc ggccagaaga cctggagctc ccgcgcggcg ttcgcggacc
    12841 gcgcgttcgg cctgttccgc accggccccg gcgaacgcca ccgcggcctg acctacctgc
    12901 tcttcgacct gcgttcggac ggcgtcaccg tgcgcccgat cgaccagctc gacggcgagc
    12961 cgggcttcgc cgagatcttc ctggacgacg tgttcgtgcc ggaccacgac gtcgtcggcg
    13021 aggtcggcga cggctggcgc gtggcgatga gcaccgcggg caacgagcgt ggcctcaccc
    13081 tgcgctcacc gggccgtttc accgccgcgg cctcccgcct ggtcgagctc taccgcaaga
    13141 acccggaccc ggccctgcgc gaccgcgtcg tcgacgcgtg gatcggcgca caggcctacc
    13201 gcctccacac cttcggtgcc ctggcctcgc cgttgagcgg accggccgcg agcgtgacga
    13261 aggtgttctg gtcggagctg gacgtcgccc tgcacgagac ggcgctcgac ctcctgggcg
    13321 aggtggcgcc ggggtggcgg gacgggtggc tgttctcgtt gtcggggccg atctacgcgg
    13381 gcaccaacga gatccagcgc aacgtgatcg ccgaacgact cctggggctg ccgcgatgat
    13441 gttcacgctc tcggcggagc agaccgactt cgcctccgtg ctgcacgact tcctgggggc
    13501 gggcgggacg gacctggcgt cgctcggggt ggacgaggtg acggacccgg tcgacctggt
    13561 ggtgctgttc gaggaggtgg ggcaccacgc ggtggcggga ccgctggtgg agacgctcgc
    13621 ggtggttccg gcgctgatcg ggtcgtcggg cggatcgagc tgttccgtgg cgttccctcc
    13681 cctgctcccc cacgccctcg aagccgaccg ctacctcctg gtcgacggcg agaccctccg
    13741 cgagggcact cccaccaccg aactcgactc cgtcgacccc acgcgccgcc tggtcgaact
    13801 cacccccggc ccggtgatcg cgaccggcgc gcccaccgcc agagcgttcg atctgggcgt
    13861 cctcaccacc tccgcccagc tcctgggcct cggccgcgcc ctgctcgaga tgaccaccga
    13921 gcacgccaag gcccgcaccc agttcggcac gccgatcggc cggttccagg cggtcaagca
    13981 ccacctcgcg aacgtcctca tcggactcga gctcgcccgg ccgctggtgt tcggcgccgc
    14041 cgtgaccatg agcgcgcggg acgtgtccgc cgccaaggtc gccacctccg acgccgcgtg
    14101 gcaggccgct cgcgtcgcgt tgcaggtgca cggggcgatc gggtacaccg ccgagcacgg
    14161 gctcgggcgg ttcctgctgc agacccgagc cctgcgcacg gcgtggggca gtccgtcgat
    14221 gcaccgagca cgtgtgctgg aggcgttgtg acaccggaac aactggctct cagggacgcc
    14281 gtccgcagcc tgctggagaa gcactcggac gtgcgcgcgg ccatcgagac cccgcacggc
    14341 tacgacaagg acctgtgggc ccggctcacc gacatcggcg tgctgccgat ccccgagcga
    14401 tacggcggtt cgggcgcgac acgagccgag accaccatcg cgctcgaaga gctcggccgc
    14461 accctcacgc cctcgccgct gctggcgtcg atgctggccg tcgaggcgct gctggccgcg
    14521 gagaacgagg aggcgtgcga gcggttgttg ccgcggatcg cggacgggac ggtcgccacg
    14581 ctcatctggc cctggcacgg caccgagtac gacctcgacg gtccagcgcg ctacgtgctg
    14641 aacggcgaca ccgccgagat cgtcctcgcg accgacggca ccgacctgta cgaggtcgac
    14701 cccggcgccg cccgcgagca caccccgacc atggaccaga cccgccgcct cgccaccgtc
    14761 acacccagcg gcgccacccg cctgggtccg tgggatccgc aaatccgcga catcgcattg
    14821 gccgcgttgt gcgccgaaca ggtcggcacg gccgcgcgag ccctggagct caccgtcgag
    14881 tacaccaaga ccagggtcca gttcggcagg ccgatcggct cgttccaggc gttgaagcac
    14941 cgcatggccg acatgcacgt tctggtggag accgcgaggt cggccgcggg agcggtcacc
    15001 gacgagatct cggcggcggt ggcgaaggtg tactgctcgg aggcgttgtt cgaggtcgcg
    15061 gccgagatgg tccagttgca cggcggcatc gcgatcacgt gggagcacga cgcgcacctc
    15121 tacctgaagc gggcgcacgg cagcggacag ctgttcggca gccctgtcgt gcacctcgaa
    15181 cgcctcaagg ccaaaatctg acaggtggac gtcaagacct acgcggtggt cacggacctg
    15241 tgcgcgcggt tcgcgggccg gctggacgac gacgcgctga actcggtgcg ggtgcactac
    15301 ttcgccgggg agcccgcgct ggcggaggcg acgctgctgc tcaccctggc gaacgaggac
    15361 atcggcatca cgcgggagga gcacgacctc atccggtccg cctcggacga ccccgacctg
    15421 gccgctgtgc gcatcatcga ccagctaccg ccgctcgcct accgcttcag ccccaccggt
    15481 cccgcggacg cgccggaccc ggccagggcc gaccaggtgc tggccgacga ggcggcgcgg
    15541 tacggcggcc gcgtgctccg gcgcgcgtgg cgcgacccgt tgcccggcgc tccggacacc
    15601 gcgaagtgga cgtacctgct gcacaccgac gacgccgacg tgctcggggt gtacgcgggc
    15661 ctgtccggac ggctccgggt cacgctggag gagaggtggc cgctggaggt ggtgcacacc
    15721 aacgtgtccc cgtaccaggc cgccgcctca ctggccccgc ggatctgggt ggcctaggag
    15781 gctccggaac ctggggcact ccaggtgcgt cggcgccggg cacgccgccg cgtgccgcag
    15841 gtcgtcgcgc atcaacgcca gcttctggat cgtcgcgtcc agttcgtcgg ccttcgcggc
    15901 gagcatctcg cggttcggcg acgggcggcc gtcgggcgag aacatcagcg tgatctcgtc
    15961 gagcgagaac cccgccgtgc ggcagaccgc gatcaacgcc agctgttcca gcacggccgg
    16021 ggtgaacacg cgcgtcaggc cttgccgtcg cacggaggcg atcaggccgc gctcctcgta
    16081 gtagcgcagg gtcgaggccg gcacgcccga acggcggacc acctcgccga tgccgatctc
    16141 agcggaatcc acgacacttg acctcaagcc gacttgaagt aggacggtag gaccatgaca
    16201 tccaacagcg cccaggccga gttgtggaac gccgcggggc agggctgggc gaacgcgcag
    16261 gacatcgtgg gtctgatgct gcggcccttc caggacgtgc tcgtcgacgc cgcggcccgg
    16321 cgcccgcgca ccagcgttct cgacgtcggg tgcggcacgg gtgccgtcac gagggcgatc
    16381 gccgaggcca ccggggcggc ctgcgtgggc gtcgacatcg ccgagtcgat gctcgaagcc
    16441 gctcgcgcgc acggcaaggc ggaatacgtc cgggcggacg cgcaggtgca cacgttcgac
    16501 cggaccttcg acctggtggt gagccggttc ggggtcatgt tcttcgacga cccgaccgcc
    16561 gcgttcgcga acctgttgaa ggcgtgcacc ggcgaactgt gcttcatcac ctggcgcggc
    16621 agggacgaga acccgttcat gaccaccgcc tccgaagtcg cggcgacgct ggcaccggac
    16681 gcaccggcac ccgacctgaa cggtcccggc ccgcacgcgt tcgccgaccc cggacacacc
    16741 cgcgccgttc tcgcggacgc gggctggacg ggaatcgacg tcgagccggt cgatcggacc
    16801 tgcacgatcc ccgagaacct gctcgccacg tacctgagca acctcggccc catctcccgc
    16861 gcgctcgccg ccgtgcccgc agaggaccgc ccggggatgc tggccggcgt ccggagcgcg
    16921 ttcgacggct tcgtgcacgg cgacgaggtg cgggtgcccg ccgcgtgctg gcaggtcacc
    16981 gcgtcagctc cactctgact ggcgctgcca cgtcaggagg gtgtcgagca cctcgccgga
    17041 ccagccgcgc gggtccagct cggcgtgcga ggcgtaccgg ccgcggtaga acagcagcgg
    17101 ctgcgcctcg cgcaccggac ccagctcgac cacggaaccg acgaccatgt ggtggtcgcc
    17161 ggcgtcgtgc accaccgaca cctggcagtc gacccacgtg agggcgccgt cgagcaccgg
    17221 agcgccggtg gccgacggcg tccacgacac cccggcgaac ttgtccgcgc ccgccctgcc
    17281 gaacaccgtg gagatctccc gctggtcctc cgccagcacg ttcacgcaga acgagccgga
    17341 cgacgccatc gccgtccagc tccgcgaagt ccgctgtgga cagaacacca ccagcggcgg
    17401 gtccagcgac agagcggcga acgcctggca ggcgaacccg acgggaccgt ccggggacat
    17461 gcccgtcacc acggtcaccc cggtgcagaa gtggccgaga accgagcggt agcgggccgt
    17521 tacctctgac cgcattattt ctggtggcca acgctgaagt cgtgtcccca caggctcacc
    17581 gccgtgctct cgcgtgcgat ccagtcctca tcgtccacct gccgtccctc gcagccgaac
    17641 tcgacgtcga agccaccggg cgtcttcatg tagaacgaca gcatcaggtc gttgacgtgc
    17701 cggcccaggg tcgccgacat cggcaccttg cgccgcaggg cgcggtccag cgtcaggccc
    17761 acgtcgtcgg tgttctcgac ctcgaccatc aggtgcacga tcccgctcgg cgtcggcatc
    17821 ggcaggaacg cgaggctgtg gtggcgcggg ttgcagccga agaaccgcag ccacgcgggt
    17881 ggtccgtcgg cggggcggcc gacgaactgc ggtggcaggc gcatcgagtc gcgcaaccgg
    17941 aaccccagca cgtcgcggta gaagtgcagc gcggcctcgt cgtccgaagt ggacagcacg
    18001 acgtgcccga gcccctgctc ctccgtcacg aaccggtgcc cgtacggcga caccacgcgc
    18061 cggtgctcca aagccgcgcc gtggaacacc tccaaggtgt tcccggacgg gtcctcgaac
    18121 cggatcagcc cggtgacgcg ccgttcggcc agatcttctg ccgagccctc gacgtacgag
    18181 acaccggcgg aggccaggcg tttcgcgacc tcttcgagtt cggcctcggt ggccgcctcc
    18241 cagccggagg cctgcaaccg gtcctcctcg cccggcacga tcacgagccg tgccgggaag
    18301 tcgtccatcc gcaggtagag cgcgccgggt gtcgaacccc tgccctccac catgccgagg
    18361 accttcaacc cgaactcgcg ccaccggtcc aggtcggtgg cctcgatccg gagatacccc
    18421 agcgaccgga tgcccatcac gcctccgtca ggaaatcgag ggcgagcctg ttgaactcgt
    18481 cgaacttctc gagctgcgcc cagtgcccgc accctccgaa cacgtgcagc tgtgcccgcg
    18541 ggatcagttt cgtcgccagc aacgcgccgt cgagcgggtt gacccggtcc tcccggcccc
    18601 acacgagcag aacccgctgg cgcagcttgt aggcctcgcg ccagagcatg ccctgctcga
    18661 agtcgggacc ggagaacgac ctgcccaagg ccgccatcgc gcgcagcgac tccggttgcc
    18721 gggccgcctc gaaccgttcg tcgaccagct cctcggtgat cagcgactgg tcgaagacca
    18781 tgatccgcag gaactcctcg atcttctccc gcgtgggcgt gcgggcgaac gcgctgagct
    18841 tgcgcacgcc ctcggtcggg tcgggcgaga agacgttgag cgacaaccca cccggcccca
    18901 tcagcaccag ccggcccgcg cgtttcccgt ggtcgagagc gaatcggacc gcggtaccac
    18961 cgcccagcga gttgcccagg acgtgcgccc gctccactcc caactcgtcg agcaggtcca
    19021 gcaacgccct ggaggcgaag gagaagtact ggtcgtgctc ggccggcttg tccgactggc
    19081 cgtagcccgg catgtcgacc gccagcaccc ggaacgactt cgcgaacacc gggatgttcg
    19141 cgcggaagtt cgacagcgcc gacgcaccgg gcccgccgcc gtgcagcatg accagtgtct
    19201 cggcgttgtc cgcgcccgcc tcgtggtagt gcaaccgcac gctcatcaac gccccctcag
    19261 aagagcccgt cgcggacctg gatgccgagc tcgttcttgc cgtacagcac gagcacgcgt
    19321 tccgggtcgt tgcccgcgtg cacccgtgcg gcgtgcgcgt cgcgccagaa ccggggcaac
    19381 ggcagtccgg cgttgatcgc cttgccgccc gcgctctcga agagcaggtc gatcgcgccg
    19441 agcgcccgcc cgctgccgag cacctggtcg cgccgggccc gcaggcgcag gtcgagcggg
    19501 atcttcgtgt cggcgacggc gtgcgcccac tcctcggtga tgtccttctc gagcgtccac
    19561 cacgccacgt cgatgtcggc cgccgcggtc gcgatcctga cctgcgcgaa cgggtcgtcg
    19621 accgacttct cgcccaggta cgccgcccgg acgcggtcgc gggtcgcgcc gacgtgcagc
    19681 gcgtacgcgc cggtcgccat gccgatgatc ggcgccgtca ccgcgtacgg gtggatcgtc
    19741 ccgtacggca tgcggaacaa cgggccgggg ttgacctcct ggccggggca cttgcagcgc
    19801 gcggtgttcg ccatgctcag cgcccggtac tccggcacga acacgtcgtc caccacgatg
    19861 tcgttgctgc ccgtgccgcg caggccgacg gtgtcccaga cgtcgttgat cgtgtagtcc
    19921 gcgatcggca gcaggaacgt gcggaagtcg accggcttgc cctcgtcgtt catgacgagc
    19981 ccgccgagca gcacccaggt cgcgtggtcg cagccggacg agaagctcca cctgccgctg
    20041 aaccggaacc cgccctcgac cgccttcgcc cggcccgtcg gcgcgtagga ggacgagatg
    20101 cgcgtgtcct ggtcctcgcc gaagacctcg gcctgcgcgc ggtcgtcgaa cagcccgacg
    20161 tgccacgggt gcacgcccag cacggacgcg acccaacccg tcgagccgca cgcgctcgcg
    20221 atcaggcgca cggcggtgta gaagtcgagc gggtgcgact cgaagccgcc gtaccgcgcg
    20281 ggttgcagca tccggaagaa gccggtctcc tgcaacgtct tgatggtctc cggcggcacc
    20341 ctgcgcagct cctccgcctc gcccgcgcgt tcggccagcg tcggcagcag ttcccgcacc
    20401 ttgccgagga tttcctcgct catcggacgt tctccctgct cagctccagt gcgatgtcga
    20461 tcagctggtc ctcctgcccg ccgacgagct tgcgctcgcc cgcgcggacg aggatctgcg
    20521 cgccggacac gccgtagcgc tgtgcctgcg tgtaggcgtg tttgaggaag ctggagtaga
    20581 cgcccgcgta gcccatcatc agcgccatcc ggtcgagcag gcactcgtcg ggcatgacgg
    20641 gccggacgac gtcctcggcc gcgtccacga tcttgaagaa gtcgacgccc gtctcgaaac
    20701 cgagcttgtc gcacacgccg acgaacgcct ccagcggcgt gttccccgct cccgcaccga
    20761 atccgcgcac gctgccgtcg atctgctcgg cacccgcccg tgccgcggcg acggagttcg
    20821 cgacgctcag cccgaggttc tcgtgcccgt ggaagccgac ctgggcgtcc ttccccagtt
    20881 ccgcgaccaa cgcctcgacg cgctcggaga cctgttccag caccagggct ccggccgagt
    20941 cgaccacgta gacgcactgg cagcccgcgt cggccatgat ccgcgcctgc ttcgccagcg
    21001 cctccggcgg ctgcgagtgg gccatcatca ggaacccgac ggtctccagc ccgcgttcgc
    21061 gtgccagccg gaagtgctgc acggacacgt cggcctcggt gcagtgcgtg gcgatccgga
    21121 cgatcgacgc gccgttgtcc tgggagatga ggatgtcgtc cttcaccccg acacccggca
    21181 gcatcagcac ggcgatcctg gcctgcgtcg cggtctcggc cgcgatcttg atcaactcct
    21241 gctccggcgt gtggctgaag ccgtagttga acgacgaccc gcccagcccg tcgccgtgcg
    21301 tcacctcgat caccggcacc ccggcgccgt cgagtgccgc gacgatcgag cgcacgtcgt
    21361 ccgccgtgaa ctggtgtcgc ttgtggtgcg agccgtcacg cagtgacgtg tcggtgagcc
    21421 gcagctgcat tggcgatctc ctcccccacc ttggtcgcgg cggccgtcat gatgtcgagg
    21481 ttcccggcgt actcgggcag gaagtcgccc gctccggcga cctcgacgaa gatcgcgacg
    21541 cgaccggcgt cgtactgcgg ctcgcgcaac aaccggaatc ccggcacgta cgaacggatg
    21601 tccgtctcca tgcgcgcgat cgagtcggtg atcgggtccg gatcggtgtc ctcggggatc
    21661 gcgcagaaga tcgtgtcgcg catgatcatc ggcgggtcgg ccgggttcag cacgatgatc
    21721 gccttgcccc tggaggcacc cccgatctcc tcgatgcccc ggctggtcgt gcgggtgaac
    21781 tcgtctatgt tggcccgcgt gcccggcccc gccgacaccg acgcgacgct cgcgacgatc
    21841 tcggcgtacg acaccggcac gacccgggac accgcgtgca ccatggggat cgtggcctga
    21901 ccgccgcacg tgatcaggtt gatgttgggc gcgtccgcgt gctcaccgag gttgaccggc
    21961 ggcacgacgt acggcccgac cgcggccggt gtcaggtcga tcgcccgcac gcccgcctcg
    22021 gcgtagcgcg gcgcgttggc ccggtgcacc gccgcggacg tcgcctcgaa cacgacgtcc
    22081 ggcagttcgt cctggcgcag caaccactcc gcgccgtcca ccgagacctc gagccccagg
    22141 tcggccgcgc gccgcagccc ctcgctggcc gggtcgacgc ccaccatcca gcgcggttcc
    22201 agcgcgtccg agcgcaggag cttgtagagc aggtcggtgc cgatgttgcc ggagccgacg
    22261 atggccgcct tcacccagtc acctcattcg aatttcaggt cgacggagcc gagtccggcg
    22321 aactcggcgt ggaactcgtc gccgggcctg gcgtcgatgg cacgggtgca cgacccgggc
    22381 agcacgatgt cgcccgccag cagccggacg ccgaagcccg cgaccttcgc cgcgagccac
    22441 gccacggcga tcgccggatc gcccagcacg gcgtcacccc gcccttcggc gaccacctcg
    22501 ccgttgcgcc gcaacgtggc cgcgacagcg ccgatgtcca gttcggacgg acgcacgcgc
    22561 tccgacccga gcatgaaccc ggccgacgac gcgttgtcgg cgatggtgtc ctgcaggccg
    22621 atccgccagt tctcgatccg gctgtcgatc aactcgatgg cggggacgac gaactcggtc
    22681 gcctccagca cgtcctgcac ggtgcacccc tcgcccggca ggtcgcgggc cagcaggaac
    22741 gcgatctcca cctccaccct cgggtagagg tacgccgagg cgtccgcggt gccggcgagc
    22801 tgcatgtcgt cgagcaggtg gccgtagtcg ggctcgtcga cgcccatcat ctgctgcatc
    22861 gccaacgacg acaggccgac cttgtgcccg atgacgtcgc ggttgcgatg gcggacgttc
    22921 agcagctgga tctcgtacgc gtcgacgacg tcgatctcgg gatacagctc caccagcggt
    22981 ttgatgggca cgcggtcgcg ttccgccgtg cgcagcagtt cggcggccgc ctccctggac
    23041 tggatcgtca gcacctggcc tccttcgcga cgtgacttcc cgcccggcga ccggagaaga
    23101 cgcagtcggc gagcgcgagg ccgctgacgt aggactccga gcacacgccg accgccgacc
    23161 ggccggccgc gtacagcccc ggaaccccct gcacctggcc cgtgtcctcg tccacgacga
    23221 gcccgccgag cgtgagcatc gggcacgggt aaccgaaccc cgcgcgcacc gacacgttga
    23281 tcaacgaata gggcggcgtc ccgaacggct cgggcgtcgc gataccggcc ttcctggcca
    23341 cttcctcgat cgtgggcgcg gtgacgaggc cacggccgag caggtggcgg acctgccagc
    23401 gctggaacgg cgcggtctgg gtgcggacct gggcacgggc gacctggagg atctcgtcgt
    23461 cgaccagcag ccaggccttg ccgccccgcg cgacgatctc gctcccgttg gcggcgccgt
    23521 acaacctcgc gtcaccgaag cgctgtcccg ccgagtcgac caggacaccg cgctgcaagg
    23581 cactgggcgg cgtgacgaac cgccacaccg agatcctgtc catccgcgcg gtcctccccc
    23641 cggcggcgac gccgagccgg atcccgccgc cgtcgtcgcc cggcgtgccg agcgcgagtc
    23701 cgccgcggtg ggccggtgcg tgctcgtgca ccagggccct gtcggcgatg aagccgccgg
    23761 ccgcgatgac cacgccctgc ccggcggtga tcaccagcgg ccggctgaac cgttcgagcc
    23821 gtgcggccag cccgaacagc ctcctgccca acggcgggta gtacagccac ggtttggcgc
    23881 ccgccttgga caacgcgctg tgcaggacgc gcggaagacc ggtgagcgca cggcaccgca
    23941 cgcccgtcac gcggccgttc tcctggacca gctctacggc gcgggtctgc ggcatgatcc
    24001 gcacgcccgc gcgccgggtc gcctcggcca gccgggtgaa gaactccctg cccgacgtgc
    24061 ccttcgccct ggtccggtgc ccgcggggcg ccgggtcggg ccaggcgtcc tcgctgccgg
    24121 acaggtagag gtagtagtcg tcggtcgggt acgaggtctt gaacggcgac agccgcgcgt
    24181 cgaacgggac gccctggtcc tcgagccagg ccaacatctt cgcgctgtcc tcgcagaagc
    24241 gccgcagggt ctccggcgac acggcgtcgc ggacctcgtg ccgcaggtag gagtacatcg
    24301 cgtcgaccga gtccggcacg cccgcctcga cctgctgccg cgtcccgcca cccgcgtaga
    24361 cgaccccgcc ggacaacgcg gtcgcgcccc cgccaccgaa ccggtccagc accaccacgg
    24421 acgcaccgga cgcggcggcc tcgacggcgg cgcacgcgcc ggccgcgccg aagccgatga
    24481 cgacgacgtc cgcggtgacc tccacgcaac cctcctggaa caggctcttg gccagaaaca
    24541 ggttcttggt gagtcgactt gcctggaact cctacaccat agcgccaaac cgcctcagaa
    24601 ctataacctg ttctagtctt agcttccggg aggtgcgatg tacgacgtga tcgtcgtcgg
    24661 cagcggcgcg gcgggcatga cagccgcgct ctgcaccgct caacacggcc tgcggacctt
    24721 gatcatcgag aaggccgcgc actacggcgg gtccaccgcg aggtccggtg gcggcatctg
    24781 ggtgccgaac aacgccgtgg tcgccgccag cggcgtcagc gactcaccgg agcgggccgg
    24841 cacctacctg gggcacatcg cgcccgaggt ccccgccgag ctgcgccagg cgttcctgga
    24901 cgcgggaccg gccatgctgg cgttcgtccg cgcgcacaca ccgctggagt tccgctgggt
    24961 ccgcgactac tccgactact acccggaggc gcctggcggg cagccgcgcg gccggtcggt
    25021 cgagccgttg ccgttcaaga cgaagctgct cggcgaggag gtcgaggacc tcgaaccgcc
    25081 gtacgtgccg acgcccgcgg gcatcgtgat cacccagacc gactaccgct ggctgacgct
    25141 gatcggacgg cacccgcgcg gaatcgccac cgcggccaag gtgttcgtcc gccggttcct
    25201 gccgggccgc cgcctcacca tgggccaggc cctgaccgcg ggactgcgtg ccggtctgaa
    25261 agcactgaac gtcgagatca ggctcaacac ggcgatgacc gaccttcacc acgagaacgg
    25321 ccgcgtcgcc ggagtgctcg tcggggagaa gctcatcctg gcgaagcacg tggtgctggc
    25381 gtgcggtggc ttcgagcaca acgagcagat gcgcaagcag caccagaaca tcggtaccga
    25441 gtggacggtc ggcgccaagg ccaacacggg tgacggcatc gaggcaggcc aacgcgccgg
    25501 cgcggccgtc gggctgatgg acgacgcctg gtggggaccg tccgtcccgt tgccgcgcgg
    25561 cccgttcttc ctgctggcgg aacggtcgct gcccggctgc gtgctggtcg acaagaccgg
    25621 ccgccggttc gtcaacgagt cggcgcccta catcgacgtg gtcaacgcga tgaccggcga
    25681 cacctggctc gtgttcgacc actcctaccg cggccgctac ccgttctgcg gcatcccgcc
    25741 acggcgtccg ctcccccggc ggtggaagga ctccgtcctc accgctccca gcctcgaaga
    25801 actcgcgcag caggccgatc tgccggaact cgtggacacc gtgcggcggt tcaacacgct
    25861 ctcggtcgcc ggcgaggaca ccgacttcca ccgcggcgac agtgcctacg accgctacta
    25921 cggcgatccc cgcaccaagc ccaaccccaa cctggcgccg ctgaccaccg gaccgttcta
    25981 cgcggtcagg atcgtgcccg gcgacctcgg caccaagggc ggcctgcgca ccgacgcctc
    26041 cgcgcgggtg ctgcgcgagg acggttcggt gatcgagggc ctgtacgcgg cgggcaacac
    26101 cagcgcttcc gtcatgggcc acacctacgc gggcgcgggc gccaccctcg gaccggcgat
    26161 gacgttcgga tacctcgccg gcctcgacat cactggagga gagcgatgac gcaggacggt
    26221 gtgcggacga tcgacgcggg cgcgcccccg gcccggttcg cgcgcggctg gcactgcctc
    26281 ggcctcgcga gccacttccg cgacggcaag ccccacgccg tcgaggcgtt cggcacgaag
    26341 ctcgtggtgt tcgcctcgga ggacggcgag atcaacgtgc tcgacgggta ctgccggcac
    26401 atgggcggcg acctcaccca gggcacggtc aagggcaaca ccctcgcctg cccgttccac
    26461 gactggcgct gggcgggcaa cggccgctgc gtcgacatcc cctacgccaa gcgcgtcccg
    26521 ctgcgggcgc gcacccggtc gtggatcacg ctggaggaga acaagcagct cttcgtgtgg
    26581 aacgacccgc agggcaaccc gccgcccgag cacgtcacga tcccgcgcat cgacgcggcg
    26641 ttctcgaccg agtggagcaa ctggacctgg gactccgtcg tcatcgacaa cgcgaactgc
    26701 cgcgagatca tcgacaacgt cgtcgacatg gcccacttct tctacatcca cttcgcgttc
    26761 ccgatctact tcaagaacgt gatggagggc cacgtcgcct cgcagtacct gaccacgcgc
    26821 ggccgtccgg acgtggcgat gggctcgaac tacaccggag acgtggaggt ccggtcggag
    26881 gccgcgtact acgggccgtc gtacatgatc gactacctgt ggaacgacta caagggcctc
    26941 gagatcgaga cggtcctgat caactgccac tacccgatct cgccgacgtc gttcaagctc
    27001 cagtggggcg cgatcgtgaa gaagctgccg ggcgtggacg acgagcacgc cgacaagatc
    27061 gcggcgaagt tcgcgcgcgg catcggggtc gggttcctgc aggacgtcga gatctggcag
    27121 aacaagtcgc gcgtcgacaa cccgttgctg tgcgaggagg acggtccggt ctaccagctc
    27181 cggcgctggt acgagcagtt ctacgtcgac gtcgaggacg tcagcgacga catggtgcgg
    27241 cgcttcgagt tcgaggtcga cacgagcagg gcgatcgagg tgtgggagaa ggaggtcgcc
    27301 gagaacctgg ccaggcagca gccccaggag caggcgacgt gagcgagcgc gacgagttcc
    27361 tgaagggcgg catggttccc gtgggctgcg actgcgggaa ccgggtgctg gtgaagaaga
    27421 acagcccgca gcacaccagc gtgcagtggc tctccgacac caggaactgc cccgagttgt
    27481 gcggtgcgcg ggccgccttg gtgccgacct gcctgcggtt gcgcgacagc atcgagaagg
    27541 ccgtgcgcga ggggacgctg gaggtcgccg atggctgagg tgcaccggct gcgggtcgac
    27601 gccgtgatcg aggagaccgc cgacgcgcgt tcgttcgtgc tgtcaggcgc ggacttctca
    27661 ccacggcccg gccagttcct gaccgtgcgg gcgggcgagg tggcgcgctg ctactcgctg
    27721 tccagcgcgc cgggcgaacc gttgaagatc accgtcaagc gcacgcccga cgggtacggg
    27781 tcgctgtgga tgtgttcgga actgcgggcc ggcatggaac tcgacgtgct ggcaccggcc
    27841 ggggtgttca cgccctcgtc gctggacggg tcgctgctcg cgttcgccgc gggcagcggg
    27901 atcacgccgg tcatgtcgat catcagggcc gtgctgcacg gcggctccgg gcaggtgttc
    27961 ctcttctacg ccaaccggga cgagtcctcg gtgatcttcg ccggcgaact gtccgagctg
    28021 gctcgcgcgc acccggaccg gctgaccgtc gtgcactggc tcgaatcggt gcaggggctg
    28081 ccgcacggcc tgcgggcgtt cgtccgcccc tgcgacgagg cgttcgtgtg cgggccggtg
    28141 ccgttcatgg aggccgcgcg caaggcactg cacgacgttc cggtcgtgca cgtcgagaag
    28201 ttcgtgtcgc tgtccagcga tccgttcggc gcggaggagc cgatcgcgga cggacggccg
    28261 gacgccgtcg tcgaggtgtc gctggacggt gagcggcacc ggtttccgtg gcccgcccgg
    28321 acgaagctgc tggacctgtt gctggagagg ggactcgacg cgccctactc gtgccgggag
    28381 ggcgcgtgca gcgcgtgtgc ctgccggctg gtcgagggcg aggtcaagat gctcaacaac
    28441 gacgtgctcg actccgagga catcgccgag ggcatcgtgc tggcgtgcca gtcggttccg
    28501 gtcacggaca acgtgaagat cacctacgag tgaggggcgc ctgatgccga tcgatccttc
    28561 cgtcgccgtc ggcgcggagc ttcccgaggt caagttctcg tggaccgagt cggacgtgct
    28621 gctctaccac ctcgcgctgg gggcgacgga actccggtac gtctacgagc gggggctgcg
    28681 ggtgctgccg acgttcggcg tggtggcgcc ccgcttccac gagaccgcgg cgccggtcgt
    28741 gtcgttcccc ggtgtggaca tcgacctcgc gcgggtgctg cacggcacgc aggagatcgc
    28801 cgtgcactcg ccgctgcccg cgtccgggga ggcggtgctg cggacgcgga tctccgacgt
    28861 gtgggacaag ggcaaggccg cggtgatcgt gcaggaggcc actgccgtgg caccggacgg
    28921 gacggcgttg ttcacgaccc ggtccagcat cttcgcccgc ggtgagggcg ggttcggcgg
    28981 cgaccgcgga ccgtccggca gggtggaggt gcccgcccac gagccggact tcctgatcga
    29041 gaccgcgacc ctgccgcagc aggcctacct gtaccggctt tgtggtgacc ggaacccgct
    29101 gcacgccgat cccgagttcg cctcgcgggc cgggttcgac gcgccgatcc tgcacgggct
    29161 gtgcacgtac ggagtggtgt gcaaggccgt catcgacgcg ctgctggacg ggccggagca
    29221 ggtgtcgtcg ttctcggcca agttcgccgg ggtggtgttc cccggcgaga cgctgacgac
    29281 gcgggtgtgg cgggacggta cccggctcgt ggtgtcgacc tcggccgggg accgtcccgt
    29341 gctctccgac gccgtcctac agctggccga ggattagacc gctggtcggg acgccggtgc
    29401 cggcggtgac caggacgtgg ccgacgttcg cgacctggtt caccgcggtg ccgcggatct
    29461 gccgcacccc ctcggcgatg ccgttcatcc cgtgcaggta ggcctcgccg agctggccgc
    29521 cgtgcgggtt gagcggcagg tcgccgtcga gttcgagcgc gccagtgcga atgaagtcct
    29581 tggcctcgcc ccggccgcag aagcgcagtt cttcgagctg gaccagcacg aacggggtga
    29641 agtggtcgta gagcacggcc acgtccacat cggaccgcgt gatgcccgac ctctcccaca
    29701 gtccgcgcgc caccacgccc atctcgggca gacgcgtcag gtcgtcgcgg tagtagctgg
    29761 tcatcgtgaa ctggtcggcg ccgctgccct gcgtcgccgc cttgacgtgg gcgggcttgt
    29821 tgggcaggtc cttggcacgt tgtgccgagg tgaccacgag cgcgaccccg ccgtcgctct
    29881 cctggcagca gtcgaggagc ctcagcggtt cggcgatcca gcgcgacgac tggtggtcgt
    29941 ccagcgtgat cggccgctcg tggaaccagg cgtgcgggtt cgtggcggcg tgcttgcggt
    30001 cgatcaccgc gatccggccg aagtcctcgg acgtggcccc gtactcgtgc atgtacctct
    30061 gcgcgaacat ggcgaccatc gcggccggcg tgcccagccc catcgggtac gaccagctgt
    30121 tgtcgatgtt cgccgcggcc gcggtctgga cctgcccgaa ccggtgcccg gaccgttcgt
    30181 tgaaggcccg gtagcacacg acgacctccg ccgccccggt ctccacggcc atcgcggcct
    30241 gctggacggt cgcgcacgcc gccccgccgc cgtagtgcac ccggctgaag aacgtgagct
    30301 ccgggatgcc gagttctctc gccaccgcta tctcggcgtt ggtgtccatg gtgaagctga
    30361 ccaggccgtc cacatcggac ggtgtcagcc cggcgtcttc gagcgcggcc ctcacggcct
    30421 ccgcggcgag ctggagctcg ctgcggccgg agtccttgga gaagtcggtc gcgccgatcc
    30481 ccacgatggc ggcgttcacg cgggcacctc gatcttcacg gttccggtga cgtggtcgcc
    30541 gtgcgcggtc cggccgacga cctcgatggt caggtcctgt tgctcgcgtc cgacgacctg
    30601 gccgaagaac ttcagggtgt cgtaggcgaa gcacggcgcg ccgagccgga tgttcacctg
    30661 ccgcacgagc gcctgcgggc ccgcccagtc cgtgacgtag cgctgcacga gcccggtcgt
    30721 ggtgaggatg ttgatgaaga tgtccttcga cccgcgctgg accgcgagat cccggtcgtg
    30781 gtggacgtcc tggaagtcgc gggtggccag ggcggtgctg atcacgaacg tcggcgtggc
    30841 ctcgacgtgc cactcgggca gggaatcacc gatccgcacg gggcctccag ctcggcatcg
    30901 tcaactcttc gtcgaccttc gtgaacacga cctcgacccg ttgcccgatc gagggttcgc
    30961 cgtcgaactc gccgagcacg cgcacgccct cgtccagttc gaccagggcg atgacgaacg
    31021 gggtctgcct gcccggcacc tgcgggtggt ggtgcacgac gtagctgtag atcacgccgt
    31081 tgccgtcgga gacgaggtac ttcggtttgg tggcaccgca ttcgggacac atcggacccg
    31141 gcgggtggcg caggaggccg cagccgccgc agcgctggat gcggagctcg tgctgccggg
    31201 tgccctccca gaagtactcg gtgtcgcggt tgacggaggg gcggatggcc tgtgccttcg
    31261 gcgcctcggg tcgtggtccg ggtttctgcg cgggcttgaa cttcagcacc cggaagcgca
    31321 tctccgccac ggcctcgtcc ccgacccacc acgtgctccg ggtcgtgacg aaccacccct
    31381 cccccagccc ggtccgcttc ggcccggtca cgtcctccag gctcgtcgtc
//
