LOCUS       NZ_CP099738            21152 bp    DNA     circular CON 27-AUG-2024
DEFINITION  Lentzea sp. HUAS12 chromosome.
ACCESSION   NZ_CP099738
VERSION     NZ_CP099738.1
KEYWORDS    RefSeq.
SOURCE      Lentzea sp. HUAS12
  ORGANISM  Lentzea sp. HUAS12
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Lentzea.
REFERENCE   1  (bases 1 to 9676923)
  AUTHORS   Ping,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JUN-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_024125735.1-RS_2024_08_27
            Annotation Date                   :: 08/27/2024 06:34:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,161
            CDSs (total)                      :: 9,080
            Genes (coding)                    :: 8,988
            CDSs (with protein)               :: 8,988
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 21 of 92
            Pseudo Genes (incomplete)         :: 77 of 92
            Pseudo Genes (internal stop)      :: 3 of 92
            Pseudo Genes (multiple problems)  :: 8 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:47:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2407433
            Orig. end                         :: 2428585
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP099738.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Ping Mo.
FEATURES             Location/Qualifiers
     region          1..21152
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="13"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21152
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21152
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11152](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11152)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            719..2026
                     /locus_tag="ND450_RS10575"
                     /old_locus_tag="ND450_10575"
     CDS             719..2026
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659159.1"
                     /locus_tag="ND450_RS10575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10575"
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="WP_253325959.1"
                     /transl_table=11
                     /translation="MRFTDRSQAGRLLGGRLDHLRDQNAVVLAVPRGGVPVAVEVANAL
                     EAPLDVVVVRKLGLPFQPDVAAGAIAEGGVRVLDQRVSRLSGLTRSELAAVEHDQRREL
                     LRRLRRFRRHRPVPLKGRVAVVVDDGAATGASARAACRVARARGAARVVLATPVCPADV
                     VGLLLQDADEVVALTTPPDFDAVGRHYDDFRQVGDAEIVHALTPATGGPPPRRRVTRQR
                     SIEIPVGRIRLQADLAVPQHPVSVVVFAQAGCSARHSSRVRYLAAELNRAGVATVLAGL
                     LTQEEELDRAAVTDVSLLGHRLTAVTRWARSEPGHRSLPVGCFGTGCAAAAALRAGADP
                     RAGLAAVLGLSGHLDLAEPWLGRVRPPTLLVVGSGDAAGIAVHERLVPRLRCEHRFVVV
                     HRANGRFDEPEALDTVSRLAHDWFTAHLTSSARPSA"
     gene            2023..3126
                     /locus_tag="ND450_RS10580"
                     /old_locus_tag="ND450_10580"
     CDS             2023..3126
                     /EC_number="6.3.2.2"
                     /GO_function="GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042398 - cellular modified amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1165: carboxylate-amine ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009946332.1"
                     /locus_tag="ND450_RS10580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10580"
                     /product="glutamate--cysteine ligase"
                     /protein_id="WP_253325960.1"
                     /transl_table=11
                     /translation="MIAALSMGVEEEYLVVDAVTRRPVAAASSILAGLSEEDFHPEFSA
                     TQAEFSTRVCLDLGSLRRELERGRTSLALAARHHGALLVASGTPPLGRPGPPPVAPGAR
                     YRRMAAVYGALVEDQGVCGCHVHVGVPDPDHAIRASNHIRPWLPALLVLSANSPFSDGR
                     DTRHASWRTSIWSRWPVSGVPPRFHSAAHYEDLVGRLVDAGVIIDPGMVYYYVRPSRHA
                     PTVEVRIADVAATVDEALLQAALTRALVSTALISSAEEPAPDAVLRAACSRAALAGLEG
                     RCLDPASGRPCTGWDLVDRLVAHVRLALRDTGDLGFVERRLSWLRRCGGGATRQRRVLD
                     ERGDLGAVVDHLAVVPSERQWPTAPHT"
     gene            3189..3443
                     /locus_tag="ND450_RS10585"
                     /old_locus_tag="ND450_10585"
     CDS             3189..3443
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681593.1"
                     /locus_tag="ND450_RS10585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10585"
                     /product="DUF4342 domain-containing protein"
                     /protein_id="WP_253325961.1"
                     /transl_table=11
                     /translation="MTVEHEDKVRLRGEALAEKVKQLIHEGNVRRLILKNDKGHTVMEI
                     PVTAGVVAAIAAPVVTAIGAIAAFANEWSIVVERQGEQP"
     gene            3440..4093
                     /locus_tag="ND450_RS10590"
                     /old_locus_tag="ND450_10590"
     CDS             3440..4093
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007033116.1"
                     /locus_tag="ND450_RS10590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10590"
                     /product="LiaF domain-containing protein"
                     /protein_id="WP_253325962.1"
                     /transl_table=11
                     /translation="MKPVRLWVGLVLLALGVFGILDAVDVLESGEVIAAWWPAAVVVLG
                     LVAMAAQRRVSVGPVVIAVLGLVLLANTLDWTSGDLLVPSVLAGVGVAVLVGLRRHHGT
                     RTPFALFGGASTKDRSKHLRHADVSAIFGGATLDLREAQIDSTADIEAFALFGGVDVLV
                     PHGWRVSVGGLPFMGGIDDKTDNDERKLPEDAPLLTVNGTALFGAVVVSNQPKP"
     gene            complement(4340..4741)
                     /locus_tag="ND450_RS10595"
                     /old_locus_tag="ND450_10595"
     CDS             complement(4340..4741)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012780.5"
                     /locus_tag="ND450_RS10595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10595"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_253325963.1"
                     /transl_table=11
                     /translation="MVGEDGALVGLVSGEGLVREQLRARRVARRVEDAMTPLVVAVDAE
                     TPVGEVARQLLGHHYRSLPVVCDGVVIGVVSREDLLRVHTSQDEVLAARASRLLCDNVE
                     ARSWDRAGGAVRRGGALHVPGLTRKPDGG"
     gene            4980..5450
                     /locus_tag="ND450_RS10600"
                     /old_locus_tag="ND450_10600"
     CDS             4980..5450
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018184.5"
                     /locus_tag="ND450_RS10600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10600"
                     /product="GyrI-like domain-containing protein"
                     /protein_id="WP_253325964.1"
                     /transl_table=11
                     /translation="MTYDVTLTELASTTTCHQRVHTTAAGIAGAVGRGLQELYEFAADC
                     SAAPTGPPQLALAGPLTDGDVTLDLYLPISATPAARGPIDVVVLPEGPAAQTFHHGRYE
                     DVPAAYEAVFAWIREHGRHQAGPPRELYLTGPDTATNPADYLTEVVVPLRRD"
     gene            complement(5411..6793)
                     /locus_tag="ND450_RS10605"
                     /old_locus_tag="ND450_10605"
     CDS             complement(5411..6793)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020639773.1"
                     /locus_tag="ND450_RS10605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10605"
                     /product="DUF4389 domain-containing protein"
                     /protein_id="WP_253325965.1"
                     /transl_table=11
                     /translation="MTTAATGYPVHVHARLDPGLSRWLWLVKWFLAIPHYLVLAFLWLG
                     FAVFSLVAFFAILFTGRYPRVLFDFNVGVLRWSWRVAYYTYGALATDRYPPFSLGPEPG
                     YPATLDIEYPEHLSRGLVLVKWWLLAIPHYLVVGVFVSGGSYIAYQTGQIIYNSGGGLV
                     GLMALFAGVALLFTGRYPKGLFDFVLGMDRWALRVAAYAGLMTDTYPPFRFDSGGDEPG
                     ATTIEQAPPPDLGHRGWSAGRVIAVVIGALLLLTGGAVAGTGGFGLWADSTQRDQAGFL
                     STGQESFRGEGYALEFGTLELRWTDADWALADGWLGEVRLRADDDVFIGIGRTDDVNRY
                     LSGVEHDEVTTTGPAATYRHRGGGAPADPAVQTFWASSGTGQVTWRAEQGSWSAVVLNA
                     DRSRVVDTRLSAQAEVPALRPVSIGLLVGGGVLLLLGLVVMLVAALSAGQSRRNGTTTS
                     VR"
     gene            complement(6804..7256)
                     /locus_tag="ND450_RS10610"
                     /old_locus_tag="ND450_10610"
     CDS             complement(6804..7256)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103010.1"
                     /locus_tag="ND450_RS10610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10610"
                     /product="universal stress protein"
                     /protein_id="WP_089920371.1"
                     /transl_table=11
                     /translation="MSTENAPIVVGVDGTPASDQALRWAVDEATYRKRPLHVVNAWNFE
                     PLVDWDETSAQKRLRESEALVAGAVEKALSGRVDRPVVEPRSLRGDAAEVLEEASKGAA
                     LLVVASHTGHRLRQIVLGSTSMHCVRHSSVPVVVIPVNEHSASDET"
     gene            complement(7253..7675)
                     /locus_tag="ND450_RS10615"
                     /old_locus_tag="ND450_10615"
     CDS             complement(7253..7675)
                     /EC_number="1.11.1.-"
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014608.5"
                     /locus_tag="ND450_RS10615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10615"
                     /product="OsmC family protein"
                     /protein_id="WP_253325966.1"
                     /transl_table=11
                     /translation="MTPAHRQPVLHRLVVRHVRDDEFVIRLRDHELHTDQPDSDRALSP
                     VELFVASLATCVAHYTGTFLRRHGLSREGHVVKAEYAMAIDRPARVARIHLTVHVDTSL
                     TAPQQAALQAVANHCTVHNTLRHPPEIQIRVEEELP"
     gene            complement(7721..8155)
                     /locus_tag="ND450_RS10620"
                     /old_locus_tag="ND450_10620"
     CDS             complement(7721..8155)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800749.1"
                     /locus_tag="ND450_RS10620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10620"
                     /product="universal stress protein"
                     /protein_id="WP_253325967.1"
                     /transl_table=11
                     /translation="MSDNELRPIVVGVDGSAAGAAAFRWAAAEARRWGCSLDAISVWHM
                     DYGVMTNPRAAASGLDPTSIEAENRSVLEAATADAEDADVRRILIEGDAKRLLVEMSRD
                     ARMLVVGNRGRGTVSELLLGSVSAYCVHHATCPVVVVKTP"
     gene            complement(8228..8788)
                     /locus_tag="ND450_RS10625"
                     /old_locus_tag="ND450_10625"
     CDS             complement(8228..8788)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016836.5"
                     /locus_tag="ND450_RS10625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10625"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_089920366.1"
                     /transl_table=11
                     /translation="MNAADVMSSPAIAVSPGTTVRAASAMLGDHGFSALPVVDDDGRLV
                     GIVSGADLLLAGMSPETAQAPVSKVMRGSVVSASATASPAELTATMLAKRLRCLPIVTE
                     EQVLVGVVSRSDLLRILTPADAVLAARVETTLRAYSGGPRWTVAVRDGEVSVSGTFADQ
                     AERKVVEALVRTVPGVRGTRVAC"
     misc_feature    complement(8855..8868)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
     misc_feature    8856..8869
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            complement(8867..9745)
                     /locus_tag="ND450_RS10630"
                     /old_locus_tag="ND450_10630"
     CDS             complement(8867..9745)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009154294.1"
                     /locus_tag="ND450_RS10630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10630"
                     /product="universal stress protein"
                     /protein_id="WP_253325968.1"
                     /transl_table=11
                     /translation="MRSPSAPVVAGVDGSASALAAVSWAAAECARHHLPLRLVHGYMLP
                     TSGYPEMVITGPEARQAVEQQARDWLTEAAAAARATAPDVEITTEVFCCGAGGLLVEES
                     RKARLVVVGSRGLGTVTGLLVGSTAVALAAHGHSPVVVVRGTQTPGGPVVVGVDGSPTS
                     EAAVAFAFEAASLRGAVLTAVMTTQDFTLDRAYNVSRMAVDWAQVEEDARRLLAQRLAG
                     WQDRYPDVEVRRVVVRDRPARALVRHGSEAQLLVVGSHGHGGFAGMLIGSTSQALVHHS
                     PCPLAIVRAAR"
     gene            9910..10041
                     /locus_tag="ND450_RS45700"
     CDS             9910..10041
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS45700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_256557484.1"
                     /transl_table=11
                     /translation="MRWYDTPDWEGFMAAVLMLLLWAALTAAATIIVTWWHETHHRR"
     gene            complement(10001..11152)
                     /locus_tag="ND450_RS10635"
                     /old_locus_tag="ND450_10635"
     CDS             complement(10001..11152)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103007.1"
                     /locus_tag="ND450_RS10635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10635"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_253325969.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 3.1e-47, bitscore:
                     160.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRIVIAGGGMSGLSLAAHLAVADHRHPVVVVDDGSRPVEDGAWA
                     SWSAGAGLLDAAAHRWFDKIRVHAGGRTTVLPLGRYRYRVVRGRDLAEVVHRYTDPLPG
                     FTRQRGHVDGFTDGGLVVDGRFVRARWVFDSVVGPGETPPLDAQLVFRGWRVSSERGVF
                     DAEIPTLFDFRTPQTHGASFVYVLPEDAHHALVEHTAFVAPGAAQDETAQREALAEYLA
                     EVAGATGYEVEREEHAVLPLCAAQPPRAHGHVLTIGARGGMLKASTGFAYQRVQRDSAA
                     IAWSMSRHGHPFDLPRAPGRFPLLDSVLLDVVTREPVQLERAFAALFRFRTAEPALRFL
                     DEETTLSQEMRLFAGMPAATYLAAARRRLTFSAGGASRATTSR"
     gene            11261..11863
                     /locus_tag="ND450_RS10640"
                     /old_locus_tag="ND450_10640"
     CDS             11261..11863
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS10640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_10640"
                     /product="hypothetical protein"
                     /protein_id="WP_253325970.1"
                     /transl_table=11
                     /translation="MSTKLTTGVWRAWFVWVTAGEFTGFLAPAITGALTSSGPLLVLAG
                     GIEGAVLGAAQGFALRRIIPRLSSPDWIAVTALGAVFAWSVAMLAVHYGQPLGTLPLAV
                     LLPLAAVAGMGVLLSIGLGQWFVLRRHADHAFRWVWATGIGWCAGLVVFTAFTTPLWQP
                     GEPTALVLLVGAAGGLLMAATMSAITGAALVHLLGKP"
     gene            11944..14205
                     /gene="pflB"
                     /locus_tag="ND450_RS10645"
                     /old_locus_tag="ND450_10645"
     CDS             11944..14205
                     /EC_number="2.3.1.54"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pflB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801247.1"
                     /locus_tag="ND450_RS10645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10645"
                     /product="formate C-acetyltransferase"
                     /protein_id="WP_253325971.1"
                     /transl_table=11
                     /translation="MRPGTVIEAPAHDFAWRGFRAGHWRDAIDVRDFIQANHSPYDGDA
                     AFLTGPTPRTTAVWNRLTGMFAEERARGVHDVDAHTPSSITAHAPGYIDREHELVVGLQ
                     TDAPLKRAIMPQGGLRIVESGLKTYGYELDPQVREIFTRYRKTHNDGVFDAYTAEILRA
                     RKAGVITGLPDAYGRGRIIGDYRRVPLYGVDRLIEAKRDERAALDELWSTEDVIREREE
                     LAEQIRALGELRQMAASYGYDISGPAGTGREALQWLYFAYLAAVKEQNGAAMSLGRTST
                     FLDVYLQRDLDEGRLTEREAQELVDDLVIKLRIVRFLRTPEYDQLFSGDPTWVTESIGG
                     MGSDGRPLVTRTSFRFLQTLYNLGPAPEPNLTVLWSPRLPEGFKRFCAKVSIETSSIQY
                     ENDELIRPRFSDDTAIACCVSAMRVGEQMQLFGARVNLAKALLYAVNGGRDEISGVQVT
                     PPFPPITSEYLDYDEVRAAFDRTTDWLAKTYVEALNIIHAMHDKYAYERIEMALHDHPV
                     QRLLGCGIAGLSVVADSLSAIRYARVRVVRDASGLAVDYVVEGDFPKYGNNDDRADAIA
                     VDLVESFMSKVRRHPAHRGAVHTQSVLTITSNVVYGRHTGNTPDGRRAGEPFAPGANPM
                     NGRDRHGLVAAALSVAKLPYDQAQDGISLTASITPTGLGRTPDEQVTNLVGVLDAYTDA
                     GGFHLNANVLNRETLLDAMAHPENHPQLTIRVSGYAVNFIRLTPEQQRDVINRTFHESL
                     "
     gene            14202..14933
                     /gene="pflA"
                     /locus_tag="ND450_RS10650"
                     /old_locus_tag="ND450_10650"
     CDS             14202..14933
                     /EC_number="1.97.1.4"
                     /GO_function="GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pflA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801246.1"
                     /locus_tag="ND450_RS10650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10650"
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="WP_253325972.1"
                     /sec_met_domain="Fer4_12 (E-value: 9.8e-17, bitscore: 60.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 7.5e-24, bitscore: 84.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 6.6e-08, bitscore: 31.3,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISTGSVHSWDVSTAVDGPGTRFVLFLSGCPLRCLYCHNPDTWHM
                     RDGHRTTVDEVAGEMAKFRRFIEVAGGGMTISGGEPLLQSDFTAAVLRRAKELGLHTAL
                     DTSGFLGARATDELLADTDLVLLDIKSWDPVTYRHVTGGEVTPTLEFARRLSAMRKPMW
                     IRFVLVPGHTDAWDNVEGIACFVSTLDAVERVEVLPFHKLGAPKYAALGIPFPLDDVPT
                     PDAVLLERVRRQFSERGLPTH"
     gene            14954..16177
                     /locus_tag="ND450_RS10655"
                     /old_locus_tag="ND450_10655"
     CDS             14954..16177
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0045017 - glycerolipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014998.5"
                     /locus_tag="ND450_RS10655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10655"
                     /product="wax ester/triacylglycerol synthase
                     domain-containing protein"
                     /protein_id="WP_253325973.1"
                     /transl_table=11
                     /translation="MIDRTSPADLMSLASGMQVGAVLVLQRDPGDVESLLAQRVLSVPR
                     LRRRLVATPFGGGRPIWVDDAGFDITGHVHRVVCPAPGDEAALLDIASSLVIRPLPHSA
                     PLWSATIVTGLAENRAALVVVFHHVLSDGIGGLAVLANLVDGSPAIEAEPFPAPAPSRL
                     ELVKDAWAARLRFPEHVPLAGFRWPSRGTRCSLNQPTGPRRRQTIARTSVSRLHAAAHR
                     CGATINDALLSSVMAALGTVLAKRGEDVDDLVVSVPVSTRRSTTAAHLGNSTGVMPVAL
                     PTGGDTWSRLTRIAATTRSHKKTATPMTPVFRLLQGLGIADWFMNHQHMVNTVVTNVHG
                     PDRPVRLGGVPVVGLIPLSATTGNVTVAFAALSYAGTFTVTVVADPDRTPDLAAITEAL
                     QAELDLLG"
     gene            complement(16280..17206)
                     /locus_tag="ND450_RS10660"
                     /old_locus_tag="ND450_10660"
     CDS             complement(16280..17206)
                     /NRPS_PKS="Domain: PKS_KR (39-168). E-value: 4.8e-09.
                     Score: 28.3. Matches aSDomain:
                     nrpspksdomains_ND450_RS10660_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658954.1"
                     /locus_tag="ND450_RS10660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10660"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_253325974.1"
                     /transl_table=11
                     /translation="MLDIIADRLVVPGYSKWGYRLREKSWTDLEPGALRGRRAVVTGAG
                     SGIGKATALGLARLGADVVLAVRDERKGEAARREIVAEVPGATIEVRHCDVSSPESVRR
                     FAAEMDRLDVLVHNAGVLPKERTVTADGHELTFATHVLGPLLLTDLLRPLLAASPDARV
                     VFVSSGGMYTQRLYADDPEYREGTFKGATAYARTKRMQVTLVPLLTERYACDGVAVHGM
                     HPGWADTPGVAGSLPGFHRLTRAFLRTPEEGADTVVWLAAVTPAPRAGRFWHDRRERPA
                     HVLPTTAEKPGDVAAFWRYSTSAAGLR"
     aSDomain        complement(16703..17089)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ND450_RS10660_PKS_KR.1"
                     /evalue="4.80E-09"
                     /label="ND450_RS10660_PKS_KR.1"
                     /locus_tag="ND450_RS10660"
                     /protein_end="168"
                     /protein_start="39"
                     /score="28.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVTGAGSGIGKATALGLARLGADVVLAVRDERKGEAARREIVAEV
                     PGATIEVRHCDVSSPESVRRFAAEMDRLDVLVHNAGVLPKERTVTADGHELTFATHVLG
                     PLLLTDLLRPLLAASPDARVVFVSS"
     CDS_motif       complement(17021..17089)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ND450_RS10660_0001"
                     /evalue="5.60E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="ND450_RS10660"
                     /protein_end="62"
                     /protein_start="39"
                     /score="6.2"
                     /tool="antismash"
                     /translation="VVTGAGSGIGKATALGLARLGAD"
     gene            complement(17225..17833)
                     /locus_tag="ND450_RS10665"
                     /old_locus_tag="ND450_10665"
     CDS             complement(17225..17833)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013228181.1"
                     /locus_tag="ND450_RS10665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ND450_10665"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_253325975.1"
                     /transl_table=11
                     /translation="MGGTSAAAASGRRPIIDVAIEMTARDGWAAVTMTRLAEQAGVSRQ
                     TVYNEIGSKNSLADAMLAHELGRFLTAIGTAFDRHPGDLVEAIHDAVRDVLDLARGNLL
                     VRAIASATHGADTELVPLLTTQAETLLTEVKAMLTARVEAYGTGLSGEQVEVLIDLMTR
                     TVLSHVVQPSGTPAATADGLAWLASRVLEEPARKPLRFG"
     gene            complement(17844..19232)
                     /locus_tag="ND450_RS45845"
     CDS             complement(17844..19232)
                     /EC_number="1.14.19.-"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020664814.1"
                     /locus_tag="ND450_RS45845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="fatty acid desaturase"
                     /protein_id="WP_305885215.1"
                     /transl_table=11
                     /translation="MKATVPVGSTEQWTDGKRYLWLLGLVVPSLAFLAIGMHAVTGWGV
                     WFWIGPVVVLLIVPAIDLVAGLDRGNPPDDVIERLENDRYYRWITYLYLPIQYVGFVVA
                     FWFIARGDLSVVDKIGLAVSIGCIGGIGINTAHELGHKKESHERWLSKIALAQSFYGHF
                     YIEHNRGHHVRVATPEDPASSRVGESFYRFWPRTVFGSVKSAWRLERKRYGRRDRHPYR
                     LGNDVLNAWLMSAVLWAAMIVWLGVGIVPYLLIQAVIGFSLLEVVNYMEHYGMLRQMVG
                     APGRRRYERVDPSHSWNSNNIATNVLLYHLQRHSDHHANPTRRYQTLRDFAESPVLPTG
                     YAGMILLALVPPLWRRVMDPRVQAHFGGDIGRANIQPGKRREVLARYGGTEASEVVVAD
                     SRGDATAGGMCPGCGYVYDESTGDPREGFPAGTPWSAIPDSWCCPDCGVREKIDFVAPG
                     RVTT"
     misc_feature    19293..19308
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.69"
                     /tool="antismash"
     gene            complement(19297..19590)
                     /locus_tag="ND450_RS10680"
                     /old_locus_tag="ND450_10680"
     CDS             complement(19297..19590)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ND450_RS10680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ND450_10680"
                     /product="hypothetical protein"
                     /protein_id="WP_253325976.1"
                     /transl_table=11
                     /translation="MSSCRHRVVQLRTPLSEDERLSLVEQTVLCHPAVHSVELFADEEV
                     HAEVVVWRGGSPQRTVRDISAALEAVLGEVAVTLTVVAIAHRRRDRVLWVYI"
     misc_feature    complement(20052..20065)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
ORIGIN
        1 tctcgcccgt gctgtggctg gcagtcacca acggcgtcct ggccgtgttc aacctggtgc
       61 ccgcggcgcc gctggacggc gggcgggtgc tcgccgccgc ggtgtggtgg cgcacgggtg
      121 acgagcgccg cggcaccgcg gtggcggccg tggcgggcaa ggccttcgga ctggtgctcg
      181 ccgcggccgg tctcgcgcag gtgttcgccg gcgcggtgtc cggcctctgg ctggtgctgc
      241 tcggcgccta cctggtggtc agcggagcgg cggagcagtc cgccggcgag gttcggcacc
      301 gcctcggtgg tctgctggtg cgcgacgtca tgacggcgga tccgatgatc gcgccggggt
      361 ggtggaccgt gcggagcttc ctgcgcggtc tcgtctccgg gccgcaccgg cgggtcttcc
      421 ccgtcgtgtc gttcgacgga acggtcctcg gcgtggtcag cctcgcggag ctcgcgcgag
      481 tggacgaccc gctcaccacg cggatctcgg acgcgtgccg ggcactgccg gacgtaccgg
      541 tcgcctcccc ggaggagccg ctgctcgacc tgctcgcccg gacaccgctc gggcgggatc
      601 gcgacgtcgt gctggtgctg cgcggcccga atctcgccgg cgtcgtggga cccgaggacg
      661 tggcctgggc gctggagctg tcccggagcg tgccgatcga acaccacgag gtgacgtcat
      721 gaggttcacc gaccgcagcc aggcgggccg cctgctcggt ggccggctcg accacctccg
      781 cgaccagaac gccgtcgtgc tcgcggtacc gcgcggcggt gtcccggtcg cggtggaggt
      841 ggcgaacgcc ctcgaagctc cgctggacgt cgtcgtcgtc cgcaagctgg ggctgccgtt
      901 ccagcccgac gttgccgccg gcgccatcgc cgaaggcggg gtgcgggtgc tcgaccagcg
      961 cgtgtcgcgg ctgtccggcc tgaccaggtc cgagctcgcc gccgtcgaac acgaccagcg
     1021 ccgggaactg ctgcgccggc tccgccgctt ccgccgtcac cgcccggtgc ctctgaaagg
     1081 acgcgtcgcg gtcgtcgtcg acgacggtgc cgccacgggc gcgtcggcgc gcgccgcctg
     1141 ccgggtcgcc cgtgcccgcg gggcggcgcg ggtggtcctc gcgacaccgg tgtgcccggc
     1201 ggacgtggtc ggtctcctgc ttcaggacgc cgacgaggtc gtggcgctca cgacgcctcc
     1261 ggacttcgac gcggtcggcc ggcactacga cgacttccgc caggtcggcg acgcggagat
     1321 cgtccacgcc ctcaccccgg ccaccggggg acctcctccc cggcggcgcg tgacccggca
     1381 acgctcgatc gagatacccg tcggcaggat ccggctccag gcggacctgg cggtgcccca
     1441 gcaccccgtc tccgtcgtgg tgttcgccca ggccggctgc agcgccaggc acagttcccg
     1501 cgtccggtac ctcgccgccg agctcaaccg ggccggagtg gcgacggtgc tggcgggcct
     1561 gctgacccag gaggaggagc tcgaccgcgc cgcggtgacc gacgtcagcc tgctcggtca
     1621 ccggctgacc gccgtgacga ggtgggcgag gagcgagccc ggccaccgat cactgcccgt
     1681 cgggtgcttc ggcacggggt gcgcagcggc ggcggctctg cgggcgggag cggatccgcg
     1741 ggccgggctc gccgccgtgc tcggcctgag cggtcacctc gacctcgccg agccgtggct
     1801 cggccgtgtc cggccaccga ccctgctcgt cgtcggcagc ggtgacgcgg ccggcatcgc
     1861 ggtgcacgaa cgcctcgttc cacgacttcg gtgcgaacac cggttcgtgg tggtgcaccg
     1921 ggcgaacggg cggttcgacg aaccggaggc gctcgacacc gtctcccgcc tcgcccacga
     1981 ctggttcacc gcccacctca cctcgtccgc acggccgagc gcatgatcgc cgcgctgtcg
     2041 atgggcgtcg aggaggagta cctggtcgtc gacgccgtga ccagacgccc ggtcgccgcg
     2101 gcctcctcga tcctcgcggg actgtccgaa gaggacttcc accccgagtt ctccgccacg
     2161 caggccgagt tctcgacgag ggtgtgcctc gatctcgggt cgctgcggcg cgagctcgaa
     2221 cgaggccgca cctcgctcgc gctcgcggcc cggcaccacg gcgcactcct cgtcgcgagc
     2281 ggcactcccc cgctgggccg gcccggccca ccaccagtgg cccccggcgc ccgttatcgg
     2341 cgcatggcgg cggtgtacgg cgcgctggtc gaggaccaag gtgtctgcgg ctgccacgtg
     2401 cacgtcggcg taccggaccc ggaccacgcc atccgcgcga gcaaccacat ccgcccgtgg
     2461 ctcccggccc tgctcgtgct gagcgccaac tcaccgttct ccgacggcag ggacacccgg
     2521 cacgccagct ggcgcacgag catctggtcc cggtggcccg tgtccggtgt accgccccgc
     2581 ttccacagcg ccgcccacta cgaggacctc gtcggacggc tcgtcgacgc cggggtgatc
     2641 atcgatccgg gaatggtcta ttactacgtt cgcccgtcac gccacgcccc gaccgtcgag
     2701 gtgcggatcg cggacgtcgc ggcgacggtg gacgaagcgc ttctgcaggc ggcgctcacg
     2761 cgggcgctcg tcagcaccgc cctgatctcc tccgcggagg agccggcgcc ggatgccgtg
     2821 ctgcgcgccg cctgctcccg tgcggcgctg gccggcctgg agggccggtg cctcgatccc
     2881 gcgtccggcc ggccctgcac ggggtgggac ctggtcgacc ggttggtggc gcacgtgcgg
     2941 ctcgcgctgc gggacaccgg tgacctcggc ttcgtcgaac gacgtctgtc atggctgcgc
     3001 aggtgtggcg gaggcgcgac gcgacaacgg cgggtcctcg atgaacgagg cgacctgggc
     3061 gccgtcgtcg accacctcgc cgtcgtgccg tcggagcggc agtggccgac ggccccgcac
     3121 acatgaccga aggacactgc tcgcggcacg cgccgcggga catcgttgtg gtggaaggga
     3181 gaaacgtcat gactgtcgaa cacgaggaca aggtccgcct gcggggcgag gcgctcgccg
     3241 agaaggtcaa gcagctcatc cacgagggca acgtccggcg tctgatcctc aagaacgaca
     3301 aggggcacac ggtgatggag atcccggtga ccgcgggtgt ggtcgccgcg atcgccgcgc
     3361 ccgtcgtcac ggcgatcggc gccatcgccg cgttcgcgaa cgagtggtcg atcgtcgtgg
     3421 aacggcaggg agaacagccg tgaaacccgt gcggctctgg gtcgggctgg tgctgctcgc
     3481 gctcggcgtg ttcggcatcc tcgacgcggt cgacgtgctc gagtcgggcg aggtcatcgc
     3541 ggcctggtgg cccgccgccg tggtggtcct cggtctcgtg gcgatggccg cgcagcgccg
     3601 cgtgtccgtc gggcccgtcg tgatcgcggt gctcggcctc gtgctgctcg cgaacacgct
     3661 cgactggacg agcggcgacc tgctggtgcc gtcggtgctc gcgggcgtcg gggtcgccgt
     3721 gctcgtcggc ctgcgccggc accacggcac ccgcacgccg ttcgcgctgt tcggcggtgc
     3781 cagcaccaag gaccgctcga agcacctccg gcacgccgac gtgtcggcca tcttcggtgg
     3841 cgcgacgctc gacctgcgcg aggcgcagat cgactccacc gccgacatcg aggcgttcgc
     3901 gctcttcggc ggcgtcgacg tcctggtccc gcacggctgg cgggtgtcgg tcggcgggct
     3961 gccgttcatg ggcggcatcg acgacaagac ggacaacgac gagcgcaagc tgcccgagga
     4021 cgctcccctg ctgacggtga acggcaccgc gctgttcggc gccgtggtgg tctcgaacca
     4081 gccgaaaccg tgaccgccgc cccggggagg cggcgaccgc gcggatgacg gcgcggcagg
     4141 tggggcactg tggtcgcggc accggcgaac accggtccgt ccgcccgcgt caccgaccgg
     4201 cgccgaggtc gccgcccgcc tcggcgccgg tcggtacccg gtgccagggg gccacttccc
     4261 cgtgccggca gctgactggt gtgtcctttc aggacatcat ctgactccac cctcaccgag
     4321 ctgccggcac gacctgccgt cagccgccgt ccggcttgcg ggtcagcccg ggaacgtgca
     4381 gggctccacc acgacggacc gcacccccag cacggtccca cgaacgcgcc tcgacgttgt
     4441 cgcacaacaa cctgctcgcc ctcgcggcga ggacctcgtc ctgcgaggtg tgcacccgca
     4501 gcaggtcctc ccggctcacc acaccgatca cgacgccatc gcacaccacc ggcaacgagc
     4561 ggtagtggtg gccgagcaac tgccgggcga cctcgcccac gggcgtctcg gcgtccaccg
     4621 ccaccacgag cggggtcatc gcgtcctcga cccgccgcgc cacccgccgg gcccgcagct
     4681 gttcgcgcac caggccctcg ccggacacca ggccgaccag agcgccgtcc tcaccgacca
     4741 cgggcagcgc gcggcgaagc cgtgcgctgc cacaagagcc gcggccgcct cgatcctggt
     4801 ccgccccgtc accgtcagcg cgggagagga cgtcacgtcg aaagcccgca ccgcgaccac
     4861 ctcctcggct ccgcggccag cgtcccgcct caccgggtgt gcctccaccg tcgagtggcc
     4921 ctcgtccccg agacgttcga ctctgccccg ccgcctgccc gcgaccgatt ctcggagcca
     4981 tgacgtacga cgtgacgctg acggagctgg catccacgac cacctgccac caacgggtcc
     5041 acaccaccgc ggccggaatc gccggtgcgg tcggcagagg actgcaggag ctgtacgagt
     5101 tcgccgccga ctgctcggct gcgccgaccg ggccaccgca gctcgccctt gccggtcccc
     5161 tcaccgacgg cgacgtcacg ctcgacctct acctgccgat ctcggccact cccgcggcgc
     5221 gggggccgat cgacgtcgtg gtcctgccgg aaggcccggc ggcgcagacg ttccaccacg
     5281 gccgctacga ggacgtcccg gccgcgtacg aggccgtgtt cgcgtggatc cgcgaacacg
     5341 gccgccacca ggcgggcccg ccccgggagc tctacctcac cgggccggac accgcgacga
     5401 accctgccga ctacctcacc gaggtggtgg tcccgttgcg ccgggactga ccggcggaca
     5461 acgcggccac cagcatcacg acgagaccca gcaggagcag cacgcctccg ccgacgagca
     5521 gcccgatcga caccgggcgc agcgcgggca cctcggcctg cgcggagagc cgggtgtcca
     5581 cgacccgcga gcggtcggcg ttcagcacca ccgcgctcca gctgccctgc tccgcccgcc
     5641 aggtcacctg tcccgtgccg gacgacgccc agaacgtctg gaccgccggg tccgcgggtg
     5701 cgccaccacc gcggtgccgg tacgtcgccg ccggcccggt cgtggtcacc tcgtcgtgct
     5761 ccacacccga caggtagcgg ttgacgtcgt cggtcctgcc gatgccgatg aacacgtcgt
     5821 cgtcggccct gagccgcacc tcaccgagcc agccgtccgc gagcgcccag tccgcgtcgg
     5881 tccagcgcag ctcgagcgtg ccgaactcca gcgcgtaccc ctcaccgcgg aacgactcct
     5941 ggccggtgct gaggaacccg gcctggtcgc gttgcgtcga gtcggcccac aggccgaacc
     6001 cgccggtgcc ggcgacagcg ccaccggtca gtagcaacag cgccccgatc acgaccgcga
     6061 tgacgcgtcc cgctgaccag ccgcggtgcc cgagatcggg cggtggtgcc tgttcgatcg
     6121 tcgtcgcgcc cggttcgtca ccgccggagt cgaacctgaa cggcggatag gtgtcggtca
     6181 tcagcccggc gtacgccgcc acgcgcagcg cccaccggtc catgccgagc acgaagtcga
     6241 acagcccctt ggggtaccgg ccggtgaaca gcagggccac gccggcgaac agggccatca
     6301 gtccgacgag tcccccgccg gagttgtaga tgatctgccc ggtctggtag gcgatgtagc
     6361 tgcccccgct gacgaagacc ccgacgacga ggtagtgcgg gatcgcgagc aaccaccact
     6421 tcaccagcac caggccgcgc gacaggtgct cggggtactc gatgtcgagc gtggccgggt
     6481 agccgggctc gggccccagg ctgaacggcg ggtagcggtc ggtcgcgagg gcgccgtagg
     6541 tgtagtacgc gacgcgccag gaccagcgca gcaccccgac gttgaagtcg aacagcaccc
     6601 gcggatagcg gccggtgaac aggatcgcga agaacgcgac gaggctgaac acggcgaacc
     6661 cgagccacag gaaggcgagc accaggtagt gcgggatcgc gaggaaccac ttcaccagcc
     6721 acaaccaccg gctcaggccg gggtcgagcc gggcgtgcac gtgcaccgga tagccggtcg
     6781 cggccgtggt catcgtcgtc acctcacgtc tcgtcgctcg ccgagtgctc gttcaccggg
     6841 atcacgacca ccggcacgga cgagtgccgc acgcagtgca tgctggtcga ccccagcacg
     6901 atctggcgca accggtgccc ggtgtgcgag gcgaccacca gcagcgccgc gcccttcgac
     6961 gcctcctcca gcacctcggc cgcgtcaccg cgcaggctgc gcggttcgac caccggccgg
     7021 tccacccgtc cggacaacgc cttctccacc gcaccggcca cgagcgcttc ggactcgcgc
     7081 aagcgcttct gagcactcgt ctcgtcccag tcgaccaaag gctcgaagtt ccacgcgttc
     7141 accacgtgca gcgggcgctt gcggtaggtc gcctcgtcca ccgcccagcg caacgcctgg
     7201 tcggatgcgg gcgttccgtc gacaccgacg acgatcggcg cgttctcggt gctcatggca
     7261 actcctcttc gacacggatc tggatctccg gcggatgccg gagcgtgttg tggacggtgc
     7321 agtggttggc gaccgcctgc agcgcggctt gctgcggtgc ggtgagcgag gtgtcgacgt
     7381 gcacggtgag gtggatcctg gccaccctcg cgggccggtc gatcgccatc gcgtactcgg
     7441 ccttcacgac gtggccttct cgcgagagtc catggcggcg caggaacgtg ccggtgtagt
     7501 gagcgacgca cgtcgcgagg gacgccacga acagttcgac cggtgacaac gcccggtcgc
     7561 tgtcaggctg gtcggtgtgc agttcgtggt ctcgcagccg gatgacgaac tcgtcgtcgc
     7621 ggacgtgccg gactaccagc cggtgcagca cgggctggcg gtgagctggt gtcatgactc
     7681 ggtcctccgc tggtgaacgg atctttcgcg acggcgtccg ctacggcgtt ttgaccacca
     7741 cgacggggca ggtggcgtgg tgcacgcagt aggcgctcac cgaccccagg agcagttcgg
     7801 agaccgtgcc gcgcccgcgg ttgcccacga cgagcatccg cgcgtccctg gacatctcga
     7861 cgaggagcct cttcgcgtcg ccctcgatga ggatccggcg cacgtccgcg tcctccgcgt
     7921 ccgccgtcgc ggcttcgagc acggaccggt tctcggcctc gatgctcgtg gggtcgagac
     7981 ccgaggcggc cgcgcggggg ttcgtcatca cgccgtagtc catgtgccac acggagatgg
     8041 cgtcgaggga gcacccccac cggcgcgctt ccgcggcggc ccagcggaac gcggcggcac
     8101 cggccgccga cccgtcgacg ccgaccacga tggggcggag ttcgttgtcg ctcatggtct
     8161 cagcgtctcg gtccgggcac actccggtca gtgcccgggg acctgggtgg tccgggacct
     8221 tcgtccgtca gcaggccacc cgtgtgccgc gcacgccggg caccgtgcgc accagggctt
     8281 cgaccacctt gcgctccgcc tggtcggcga acgtgccgga cacgctgacc tccccgtccc
     8341 gcaccgcgac cgtccacctg ggaccaccgc tgtacgcccg caacgtcgtc tccaccctgg
     8401 ccgccagcac ggcgtccgcc ggggtgagga tccggagcag gtcactgcgg ctcacgaccc
     8461 cgacgagcac ctgctcctcc gtcacgatcg gcaggcaccg cagccgcttc gccagcatcg
     8521 tcgcggtgag ttccgccggc gaggccgtcg cggacgcgct gaccacggag ccgcgcatca
     8581 ccttcgacac cggtgcctgg gccgtctccg gggacatgcc cgccagcagg aggtcggctc
     8641 cggagacgat cccgaccagc ctgccgtcgt cgtccaccac cggcagggcg gagaacccgt
     8701 ggtcgcccag catcgcgctc gccgcgcgga ccgtggtgcc gggactcacc gcgatcgccg
     8761 ggctggacat cacatctgca gcgttcatgc cgttgagcgt gtgcccccgc tccggctgtc
     8821 cggcagagcg ggaggccacg caggggcagt gacgttggac cctgtctcac cgcgccgcgc
     8881 ggacgatcgc cagtggacag ggtgagtggt gcacgagcgc ctggctggtc gagccgatca
     8941 gcatgcccgc gaatccgccg tgcccgtggc tgccgacgac caggagctgc gcctcggaac
     9001 cgtggcgcac gagggctcgt gcgggccggt cccgcaccac gacgcgacgc acctcgacgt
     9061 cggggtacct gtcctgccag ccggcgagcc gctgtgcgag caaccggcgt gcgtcctcct
     9121 cgacctgcgc ccagtcgacc gccatccggg agacgttgta ggcgcggtcg agggtgaagt
     9181 cctgagtcgt catgaccgcc gtcagcaccg cgccgcgcaa cgaggccgcc tcgaacgcga
     9241 acgcgacggc cgcctcgctg gtcggtgacc cgtcgacacc cacgaccacg ggacctccag
     9301 gtgtctgcgt gccacgcacg acgaccaccg ggctgtgccc gtgggccgcc agcgccaccg
     9361 ccgtggagcc gacgagaagc cccgtgacgg tgccgagccc gcgggacccg accacgacga
     9421 gccgtgcctt cctcgactcc tcgacgagca gccctcccgc accgcagcag aacacctcgg
     9481 tcgtgatctc cacgtcgggt gctgtcgcgc gcgcggccgc ggcggcctcg gtcagccagt
     9541 cgcgggcctg ctgttcgacg gcctggcgcg cctcggggcc ggtgatcacc atctccgggt
     9601 agccgctggt gggcagcatg tacccgtgca ccagccgcaa cggcaggtgg tgccgggcgc
     9661 actcggccgc ggcccagctg acggcggcga gcgccgaggc ggagccgtcg acgcccgcga
     9721 cgaccggtgc ggacggtgat ctcatgtcgt cacccgcgga agttcctcgc atgccgtcca
     9781 cgattcgccc ctgtgccgac gccccggcag ggcggacgtg cccaggccgc gcgggccctt
     9841 cgcccctcct gcccgcccgt gccgaccgcg agtctcggcg tgtcgagttc gcgacccgag
     9901 gagcgttcga tgcgctggta cgacacgccc gactgggagg gcttcatggc cgccgtgctc
     9961 atgctgctgc tgtgggccgc cctcaccgcc gcggcgacga tcatcgtgac gtggtggcac
    10021 gagacgcacc accggcgctg aaggtgagac ggcgccgcgc ggccgcgagg tacgtcgccg
    10081 ccggcatgcc cgcgaagagc cgcatctcct gcgacagcgt ggtttcctcg tcgaggaacc
    10141 gcagcgcggg ttccgccgtg cgaaagcgga acagggcggc gaacgcgcgt tcgagctgca
    10201 ccggctcgcg ggtgacgacg tcgagcagca cggagtccag cagggggaac cgccctggcg
    10261 cccgcggcag gtcgaaagga tggccgtgcc ggctcatcga ccaggcgatc gcggcgctgt
    10321 cccgttgcac gcgctggtag gcgaatccgg tggacgcctt cagcatgccg ccccgcgctc
    10381 cgatcgtgag cacgtgcccg tgtgcgcggg gaggctgcgc cgcgcacagc ggcagcaccg
    10441 cgtgctcctc ccgctcgacc tcgtacccgg tggcacccgc gacctccgcg aggtactcgg
    10501 cgagcgcctc ccgctgtgcc gtctcgtcct gcgcggctcc cggtgcgacg aacgccgtgt
    10561 gctcgaccag cgcgtgatga gcgtcttcgg gcagcacgta gacgaagctc gccccgtgcg
    10621 tctggggcgt gcggaagtcg aacaacgtgg ggatctccgc gtcgaacaca ccccgctcgc
    10681 tcgacacccg ccagccgcgg aagacgagct gggcgtcgag gggcggcgtc tcgccgggcc
    10741 cgaccacgct gtcgaacacc cagcgggcgc gcacgaaccg gccgtccacg acgaggccgc
    10801 cgtcggtgaa cccgtcgacg tgcccgcgct gacgggtgaa gcccggcagc ggatcggtgt
    10861 accggtggac gacttcggcg aggtcccgtc cccgcacgac gcggtaccgg taccgcccca
    10921 gcggcagcac ggtggtccgg ccgcccgcgt gcacccggat cttgtcgaac caccggtgtg
    10981 cggcggcgtc gagcagcccg gctcccgcgc tccaggacgc ccacgccccg tcctcgaccg
    11041 ggcgggagcc gtcgtcgacg acgaccacgg gatgccggtg gtccgcgacg gccaggtgcg
    11101 ccgcgaggct cagcccgctc atccccccac cggcgatcac gatgcgcgtc atgcccacca
    11161 ctctcaccac cgccgcgcgg cagggggaac ggcttgggga ccccggaacc gaggaccttc
    11221 gtccctgtga ccggcccggc cacccgacca tcgtggggcg atgagcacca agctgacgac
    11281 cggcgtgtgg cgggcgtggt tcgtctgggt caccgccggg gagttcaccg gtttcctcgc
    11341 gcctgccatc acgggcgcgt tgacgtcctc agggcctctg ctggttctcg cgggagggat
    11401 cgagggcgcg gtgctcggtg cggcgcaggg tttcgccctc cgccgcatca tccccaggct
    11461 gagctcgccg gactggatcg cggtcaccgc gctgggcgcc gtgttcgcct ggtcggtcgc
    11521 gatgctcgcc gtccattatg gacagccgct cggcaccctg ccgctcgcgg tgctgcttcc
    11581 gctggccgcg gtcgcgggca tgggggtcct gctgtcgatc ggtctcgggc agtggttcgt
    11641 gctgcgccgc cacgccgacc acgcgttccg gtgggtgtgg gccacgggga tcgggtggtg
    11701 tgcggggttg gtcgtgttca ccgccttcac cactcccctg tggcagcccg gtgaacccac
    11761 cgcgctcgtc ctgctcgtcg gcgccgccgg aggcctgctg atggccgcca cgatgtccgc
    11821 gatcaccggc gccgccctcg tgcacctgct gggcaagccc tgacggggcc gggaccatgg
    11881 tcccgggccc gtcacccccc acggcccctg tcccccgcgt cccggcggga cgaccgtgga
    11941 ggtatgagac ctggcaccgt gatcgaggca cccgcgcacg acttcgcctg gcgaggcttc
    12001 cgcgcgggac actggcgcga cgcgatcgac gtccgcgact tcatccaggc caaccactcg
    12061 ccctacgacg gtgacgccgc gttcctgacc ggcccgacgc cgcgcacgac cgcggtgtgg
    12121 aaccggctca ccggaatgtt cgccgaggaa cgcgcccgcg gcgtccacga cgtcgacgcg
    12181 cacaccccgt cgtccatcac ggcccacgca ccgggctaca tcgaccgcga gcacgagctc
    12241 gtcgtgggat tgcagaccga cgcgccgctc aagcgcgcga tcatgcccca aggcgggctg
    12301 cgcatcgtgg agtcgggcct caagacgtac ggctacgagc tcgacccgca ggtccgggag
    12361 atcttcaccc ggtaccgcaa gacgcacaac gacggcgtgt tcgacgccta caccgccgag
    12421 atcctgcgcg ccaggaaggc cggcgtcatc accggactcc ccgacgccta cggccgcggc
    12481 cggatcatcg gcgactaccg ccgcgtcccg ctctacggcg tcgacaggct gatcgaggcg
    12541 aagagggacg aacgcgccgc gctcgacgaa ctctggtcga ccgaggacgt catccgggag
    12601 cgcgaggagc tcgccgagca gatccgcgca ctcggggaac tgcggcagat ggccgcctcc
    12661 tacggttacg acatctcggg accggccggc accggccgcg aagccttgca gtggctgtac
    12721 ttcgcctacc tcgccgccgt gaaggagcag aacggcgccg cgatgtcgct cggccgcacc
    12781 tcgacgttcc tcgacgtgta cctccagcgc gacctcgacg agggccggct caccgagcgc
    12841 gaggcccagg agctcgtcga cgacctcgtg atcaagctgc gcatcgtccg gttcctgcgc
    12901 acgcccgagt acgaccagct gttctccggt gatcccacct gggtcaccga gtccatcggc
    12961 ggcatgggat ccgacggccg cccgctcgtc acccgcacca gcttccggtt cctgcagacc
    13021 ctgtacaacc tgggtcccgc tcccgagccc aacctgaccg tgctctggtc gccgcgcctg
    13081 ccggagggct tcaagcggtt ctgcgcgaag gtctccatcg agaccagctc catccagtac
    13141 gagaacgacg aactgatccg gccgaggttc agcgacgaca ccgccatcgc ctgctgcgtc
    13201 tccgcgatgc gcgtcggcga gcagatgcag ctgttcggtg cccgcgtcaa cctggccaag
    13261 gccctgctgt acgccgtcaa cggcggccgg gacgagatct ccggcgtcca ggtgacaccg
    13321 cccttcccgc cgatcacctc cgagtacctc gactacgacg aggtccgcgc cgcgttcgac
    13381 aggacgaccg actggctggc gaagacctac gtggaggcgc tgaacatcat ccacgcgatg
    13441 cacgacaagt acgcctacga gcgcatcgag atggccttgc acgaccaccc cgtccagcgc
    13501 ctgctgggct gcggcatcgc cggcctctcg gtcgtcgccg acagcctctc cgccatccgg
    13561 tacgcgcggg tgcgggtggt ccgcgacgcg tccggtctgg cggtcgacta cgtcgtcgag
    13621 ggcgacttcc cgaagtacgg caacaacgac gaccgggccg acgcgatcgc cgtcgacctc
    13681 gtcgagagct tcatgagcaa ggtgcgccgc caccccgccc accggggcgc cgtgcacacc
    13741 cagtccgtcc tgaccatcac ctcgaacgtg gtctacggca ggcacaccgg caacaccccc
    13801 gacggtcgcc gcgccggcga accgttcgcc cccggcgcca acccgatgaa cggccgggac
    13861 aggcacggcc tcgtcgccgc cgccctgtcc gtcgccaaac tcccctacga ccaggcgcag
    13921 gacggcatct cgctcaccgc cagcatcacc cccaccggtc tcggccgcac ccccgacgaa
    13981 caggtgacca acctggtcgg tgtgctggac gcgtacaccg acgcgggcgg gttccacctc
    14041 aacgccaacg tgctcaaccg ggagacgctc ctcgacgcca tggcccaccc cgagaaccac
    14101 ccgcagctga ccatccgcgt ctcgggttac gcggtgaact tcatccgcct cacgcccgag
    14161 cagcaacgcg acgtcatcaa ccgcaccttc cacgagtcgc tgtgatcagc accggatcag
    14221 tccactcgtg ggacgtctcc accgcggtcg acggaccggg cacccgcttc gtgctcttcc
    14281 tgagcgggtg cccgctgcgg tgcctgtact gccacaaccc cgacacctgg cacatgcgcg
    14341 acggccaccg cacgaccgtc gacgaggtgg cgggcgagat ggcgaagttc cgcaggttca
    14401 tcgaggtggc cggtggcggc atgaccatca gcggcggaga accgttgctg caatcggact
    14461 tcacggcggc tgtgctgcgc cgtgccaagg agctcggcct gcacaccgcc ctcgacacct
    14521 ccggtttcct gggtgcacga gcgaccgacg aactcctcgc cgacaccgac ctcgtgctgc
    14581 tggacatcaa gtcctgggac ccggtcacct accggcacgt gaccggcggt gaggtcaccc
    14641 cgacgctgga gttcgcgcgc aggctgtcgg cgatgcgcaa gccgatgtgg atccggttcg
    14701 tgctggttcc cggacacacc gacgcgtggg acaacgtcga aggcatcgca tgcttcgtga
    14761 gcaccctcga cgccgtcgag cgcgtggagg tgctcccctt ccacaagctc ggcgcgccga
    14821 agtacgccgc gctgggaatc ccgttcccgc tcgacgacgt gcccacgcct gatgccgtgc
    14881 tgctggagcg agttcgccgt cagttctccg aacgagggct gcccacgcac tgacgcggct
    14941 gaggagcgtt tcgatgatcg accggaccag ccccgccgac ctgatgtcgc tcgcctcggg
    15001 catgcaggtg ggcgcggtcc tggtgctgca acgcgatccc ggcgacgtcg aatccctgct
    15061 cgcccagcgc gtcctgtctg ttccccggtt gcgccgacga ctggtcgcaa ctccgttcgg
    15121 aggtgggcgc cccatctggg tcgacgacgc cgggttcgac atcaccggac acgtgcaccg
    15181 cgtggtctgc ccggctcccg gtgacgaagc ggcactgctg gacatcgcct cctcactcgt
    15241 gattcgtccc ctcccgcatt cggctccgct ctggtccgcg acgatcgtca ccgggctggc
    15301 ggagaaccga gcggcgttgg tcgtggtctt ccaccacgtg ttgtccgatg gcatcggcgg
    15361 gctcgccgtg ctggcgaacc tggtcgacgg atcaccggcc atcgaggccg aaccctttcc
    15421 agcacccgcg ccgtcccgcc tcgaactcgt gaaggacgca tgggcggccc ggttgaggtt
    15481 cccggagcac gttccgctcg caggtttccg gtggccctca cgtggcacac gctgttcctt
    15541 gaaccaaccg accgggccac gcagacggca gaccatcgcc cggaccagcg tctcccgctt
    15601 gcacgccgcc gcgcaccgct gcggtgccac gatcaatgac gccctgctca gctccgtcat
    15661 ggctgccctg ggcacggtcc tggccaagcg cggggaggac gtggacgacc tggtggtctc
    15721 cgttcccgtg tcgacgcggc gatccacgac ggccgcgcac ctcggcaaca gcaccggcgt
    15781 catgcccgtc gcactgccga ccggcggcga cacctggtcg cggctgaccc gcatcgccgc
    15841 cacgaccagg tcgcacaaga agacggccac cccgatgaca cccgtcttcc ggctgttgca
    15901 gggcctcggg atcgcggact ggttcatgaa ccaccagcac atggtgaaca ccgtcgtgac
    15961 caacgtgcac ggccctgatc gtcccgtgcg gctgggtggt gtgcctgtcg tcgggctgat
    16021 cccgttgtcc gccaccacgg gcaacgtgac cgtggcgttc gccgccctgt cctacgccgg
    16081 cacgttcacc gtcaccgtgg tcgccgaccc cgatcgcaca cccgacctgg cggcgatcac
    16141 cgaggcgctg caggccgaac tggacctgct cggctgaatc ccgcaggctg gatctgcgac
    16201 tctgcccttc cacgaggatc aaccaggcat cgcgaacgtg ttcatcaccc gtgctcccac
    16261 gatgctccac ctgggaacgt catctgagac ccgcagcgga cgtgctgtac cgccagaacg
    16321 cggcgacgtc cccgggcttc tccgcggtgg tgggcagcac gtgcgccgga cgctcccggc
    16381 ggtcgtgcca gaaccgtccg gcacgcggag cgggtgtcac cgcggcgagc cagacgacgg
    16441 tgtccgcacc ctcctccggt gtgcgcagga acgccctggt caggcggtgg aaccccggca
    16501 gcgagccggc gacacccggc gtgtcggccc agccggggtg catgccgtgc accgcgaccc
    16561 cgtcgcaggc gtagcgctcg gtcagcagcg ggacgagcgt gacctgcatg cgtttcgtgc
    16621 gcgcataggc cgtcgcgccc ttgaaggtgc cctcgcggta ctcggggtcg tcggcgtaca
    16681 ggcgttgcgt gtacatgcct cccgaggaga cgaacacgac acgcgcgtcc ggagaagccg
    16741 cgagcagcgg gcgcagcagg tcggtcagca gcaacgggcc cagcacgtgc gtggcgaacg
    16801 tcagctcgtg gccgtccgcg gtgaccgtgc gttccttcgg caggaccccg gcgttgtgca
    16861 ccagaacgtc caatcggtcc atctccgcgg cgaaccgccg cacggactcc ggactcgaca
    16921 cgtcgcagtg ccggacttcg atcgtggcac cgggtacctc ggccacgatc tcccggcgcg
    16981 cggcctcgcc cttgcgttcg tcgcgcacgg ccagcacgac gtccgcgccg agacgggcga
    17041 ggcccagcgc cgtcgccttg ccgatgccgc tgccggcccc ggtcacgacg gcccggcggc
    17101 cgcgcagtgc gccgggctcc aggtccgtcc aactcttctc gcgcagccgg tagccccact
    17161 tcgagtagcc ggggacgacg agccggtccg cgatgatgtc gagcacgctc acctccggtg
    17221 ttcgtcagcc gaagcgcagc ggtttcctcg cgggctcctc cagcacgcgt gacgcgagcc
    17281 acgccaggcc gtcggccgtg gcggcggggg tgcccgacgg ctggacgacg tggctgagga
    17341 ccgtgcgggt catgaggtcg atcagcacct cgacctgctc gccgctcagg ccggtgccgt
    17401 acgcctcgac ccgtgccgtg agcatcgcct tgacctcggt gagcagggtt tcggcctggg
    17461 tggtcagcag cggcacgagt tcggtgtcgg cgccgtgcgt cgcggaggcg atcgcacgga
    17521 ccaggaggtt gccgcgggcg aggtcgagga cgtcccggac ggcgtcgtgg atcgcctcga
    17581 ccaggtcacc ggggtggcgg tcgaacgcgg tgccgatagc cgtgaggaac cggccgagct
    17641 cgtgcgcgag catcgcgtcg gcgagggagt tcttggagcc gatctcgttg tagacggtct
    17701 ggcggctgac cccggcctgc tcggcgagcc gcgtcatggt gaccgcggcc cagccgtcac
    17761 gggcggtcat ctcgatcgcc acgtcgatga tcggccgcct gccggaggcc gctgccgcag
    17821 aagtcccgcc catgcgtcgg atcctaggtc gtcacacggc ccggcgcgac gaagtcgatc
    17881 ttctcgcgca ccccgcagtc cgggcagcac cacgagtccg ggatggccga ccacggcgtt
    17941 ccggcgggga agccctcgcg cgggtcgccg gtgctctcgt cgtagacgta cccgcagccc
    18001 gggcacatgc cgcccgcggt cgcgtcaccc cggctgtcgg ccacgacgac ctcgctcgcc
    18061 tcggtgccgc cgtagcgggc gaggacctcc cgccgtttgc ccggctggat gttggcgcgg
    18121 ccgatgtcgc cgccgaagtg ggcctgcacg cgcgggtcca tcacgcgccg ccacagcggg
    18181 ggcaccaggg cgagcaggat catgcccgcg tacccggtcg gcagcaccgg ggactcggcg
    18241 aagtcgcgca acgtctggta gcgccgggtc gggttggcgt ggtggtcgct gtgccgctgc
    18301 aggtggtaca gcagcacgtt cgtggcgatg ttgttggagt tccagctgtg gctggggtcc
    18361 acgcgctcgt agcgcctgcg gcctggtgcg ccgaccatct gccgcaacat cccgtagtgc
    18421 tccatgtagt tgacgacctc caggagcgag aagccgatca ccgcctggat gagcaggtac
    18481 ggcacgatgc cgacgcccag ccacacgatc atcgccgccc acagcaccgc cgacatcagc
    18541 cacgcgttga gcacgtcgtt gcccagccgg tacgggtgcc ggtcgcgacg cccgtaccgc
    18601 ttgcgttcga gccgccacgc cgacttgacc gacccgaaca ccgtgcgcgg ccagaagcgg
    18661 tagaagctct cgcccacgcg actgctcgcc gggtcctccg gggtggcgac ccgcacgtgg
    18721 tggccgcggt tgtgctcgat gtagaagtgg ccgtagaagc tctgcgcgag cgcgatcttc
    18781 gacagccacc gctcgtggct ctccttcttg tgccccagtt cgtgcgcggt gttgatgccg
    18841 atgccgccga tgcacccgat cgacaccgcg aggccgatct tgtccacgac ggacaggtca
    18901 ccacgggcga tgaaccagaa cgccaccacg aacccgacgt actggatcgg caggtacagg
    18961 taggtgatcc agcggtagta gcggtcgttc tccagccgtt cgatcacgtc gtcgggcggg
    19021 ttgccgcggt cgagcccagc gaccaggtcg atcgccggga cgatcagcag gaccacgacc
    19081 gggccgatcc agaaccacac gccccagccc gtgacggcgt gcatcccgat cgccaggaac
    19141 gccagggacg gcacgaccag tcccagcagc cacaggtacc gcttgccgtc cgtccactgc
    19201 tcggttgagc cgacgggcac cgttgccttc atgtcgctct cctccgggag gttgacagaa
    19261 aggtagggga tgtaaagccc gtttgacaat aggcctctag atgtaaaccc agaggacccg
    19321 gtcgcgcctg cggtgggcga ttgccacgac cgtcagggtc acagccacct caccgagcac
    19381 ggcctccaga gccgcggaga tgtcgcgaac ggtccgctgc ggcgaaccgc cgcgccacac
    19441 cacgacctcg gcgtggacct cctcgtcggc gaacagctcg acgctgtgca ccgccggatg
    19501 gcacaggacg gtctgctcga cgagcgacag ccgttcgtcc tcggacagcg gcgtgcgcaa
    19561 ctggacgact cggtggcggc agctggacaa cggaactcct cgatcagcgc gggtggcttc
    19621 ggtccgaaga gcacgcgaga tccggaaatg tcacgcacgt tcaccgaatc ggggtacgac
    19681 gccccgcagt cgcaggtagg cgagcaacgg ctgggagtgg ctgtgcaggt tcgcgacggg
    19741 gtacgcctgc atcgccgtgc cgaactccgg caacgcccac gtctcgccgg gccggtcgct
    19801 gtccggtgcg aggtagcagt cggggccgga cagcgtgccg gtccacacgt ccggatacgc
    19861 ggccgtgtgc gcgtgcagcg tcatgcgccg ccactcgtcc cacgccaggt cctcgtcgtg
    19921 cagggacgcc gcccagacca gcgtcatgtt caccgagaac cacacctggc cctgtgcgcc
    19981 ggcgggagtg ggccagcggt ggcgggcgcc cagcggtgac ccggcgcggc acgtctcgtc
    20041 gatcgtggtg agcaacgcgc gtgcctggtc cggagtcgct gcgccgcaca ggatcgccca
    20101 cggctgcatc tcgagccaca ggtcgttctc gccgaccacc gcgttccccg ggccgcgggc
    20161 gcggcggaac cagcggccgt tccactcctg cgcgaccagc tcgcggaggg cggcggcacg
    20221 gtggcgtgcc tcggaagccg tcgcggcgtc acccacccgt tcggcgagct cggcgtagac
    20281 ggggagcacc caggccgcca tggccgagtt cagcaccgac tcgccgctct tgaccatcag
    20341 ctcacggtcc actccggact cccggatggc gaggtcgctc cagtcggcgt tgaggatccg
    20401 gacgtggccg tgctcgccca ccccgacctc gtcggcgaag aaccggaact ggcgcctcag
    20461 gttctcgccg agcgggacgg cttcggcgcc gtggcacggg tggtacggca cgggttcgtg
    20521 gaacgcggcg aggtcaccgg tctcggcggc gtactcggcg gcgagccaga gcgcccagag
    20581 gttctggtcg gacgggcgga acagctgcgt ccacggctgt ttgcggccgt cgagcgcgta
    20641 cgggaggtcg ccgtccgggc tgccccaggc gcaggtgttg cgcagcaccg acagggcgag
    20701 gtccggttcg aggtgcacca gcggcagcgc gtgttgcagc ggatcccttg cggcgccgtt
    20761 gaaaccgtga cggaacgagt aggccgagcc ctggttcagg gtgtgaccgc cgagaagacc
    20821 gtcggtgcac gcgcccccgg tcagcagtgc cgcgtgccag cggatctcgt ccggcgcgga
    20881 cgggagtcgc cggcggaggg cggccaggct cgtctcgtag accgcctccg ggtccacggg
    20941 tccgtcgagc agcccgaacc ggaaccacgc ggtggtccgc tcccccggcg ccagttccag
    21001 cgggatcccg acggtcaggg ttccggcggt cgtccgcacc cgctcgcctc cggcgtgctc
    21061 cagcgccacg acgggtgcgt ccggcggagg atctccccgc accggcccga actccaggtt
    21121 cacctcgcgc ggccgcacct cccactcctc gg
//
