LOCUS       NZ_CP099468            26721 bp    DNA     linear   CON 04-JUL-2024
DEFINITION  Streptomyces phaeoluteigriseus strain Qhu-M197 chromosome, complete
            genome.
ACCESSION   NZ_CP099468
VERSION     NZ_CP099468.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces phaeoluteigriseus
  ORGANISM  Streptomyces phaeoluteigriseus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1  (bases 1 to 9026270)
  AUTHORS   Zhang,B., Xiang,X. and Fan,J.
  TITLE     Complete genome sequence of soil microorganisms Streptomyces sp.
            Qhu-M197 isolated from Alpine meadows habitats on the Tibetan
            Plateau
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9026270)
  AUTHORS   Zhang,B., Xiang,X. and Fan,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2022) Faculty of Eco-Environmental Engineering,
            qinghaiuniversity, No. 251 Ningda Road, Chengbei District, Xining
            City, Qinghai Province 810000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Hifiasm v. v0.14; Circlator v. v1.5.5; Pilon v.
            v1.22
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 68.51291x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023923245.1-RS_2024_07_04
            Annotation Date                   :: 07/04/2024 06:06:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,100
            CDSs (total)                      :: 8,006
            Genes (coding)                    :: 7,707
            CDSs (with protein)               :: 7,707
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 299
            CDSs (without protein)            :: 299
            Pseudo Genes (ambiguous residues) :: 0 of 299
            Pseudo Genes (frameshifted)       :: 130 of 299
            Pseudo Genes (incomplete)         :: 241 of 299
            Pseudo Genes (internal stop)      :: 34 of 299
            Pseudo Genes (multiple problems)  :: 90 of 299
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:40:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2830435
            Orig. end                         :: 2857156
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP099468.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26721
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26721
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26721
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16721](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16721
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(204..217)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.03"
                     /tool="antismash"
     gene            complement(239..1174)
                     /locus_tag="NFX46_RS12615"
                     /old_locus_tag="NFX46_12615"
     CDS             complement(239..1174)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339288.1"
                     /locus_tag="NFX46_RS12615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12615"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_073495851.1"
                     /transl_table=11
                     /translation="MGAGHDHGHTHVPTTGTAAAAYRGRLRAALSITLTVMVVEIVGGV
                     LADSLALIADAAHMATDALGLGMALLAIHFAGRPPTGNRTFGYARAEILAALANCLLLL
                     GVGGYVVYEAVQRFFTPAPTEGGLMIVFGGIGLAANMVSLSLLMRGQADSINVRGAFLE
                     VAADALGSVAVLVSAVVILTTGWQAADPVASLVIGLMIVPRTVKLLRETLDVLLEAAPK
                     GVDMAEVRTHMLALDGVEDVHDLHAWTITSGMPVLSAHVVVRSDVLDAIGHEKMLHELQ
                     GCLGDHFDVAHCTFQLEPSGHAQHEARLCH"
     misc_feature    1247..1261
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     misc_feature    complement(1276..1290)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.57"
                     /tool="antismash"
     gene            complement(1312..2283)
                     /gene="galE"
                     /locus_tag="NFX46_RS12620"
                     /old_locus_tag="NFX46_12620"
     CDS             complement(1312..2283)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (65-182). E-value:
                     2.7e-12. Score: 38.3. Matches aSDomain:
                     nrpspksdomains_NFX46_RS12620_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676194.1"
                     /locus_tag="NFX46_RS12620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12620"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_252548850.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.4e-17, bitscore:
                     62.6, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.2e-10,
                     bitscore: 39.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMTGAGERVVVLDDLSAGVPGRLPADV
                     PLVAGSALDAGLLKRVLAEHAVTGVVHLAARKQVAESVAQPTRYYRENVGGLATLLEAV
                     AEAGVRRFLFSSSAAVYGNPDVDLITEDTPCSPVNPYGETKLAGEWLVRAAGEAHGIAT
                     TCLRYFNVAGAAEPALADTGVFNIVPMVFDRLTRDEAPRIFGDDYPTPDGTCVRDYIHV
                     ADLAEAHLAAARRLTAPDVRGDLTVNIGRGEGVSVRELVTLIGKVTGDPRPALVEGRRP
                     GDAPRAVASAALAARELGWTASRGMREMVASAWRGWQLHHGG"
     aSDomain        complement(1738..2088)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NFX46_RS12620_NAD_binding_4.1"
                     /evalue="2.70E-12"
                     /label="NFX46_RS12620_NAD_binding_4.1"
                     /locus_tag="NFX46_RS12620"
                     /protein_end="182"
                     /protein_start="65"
                     /score="38.3"
                     /tool="antismash"
                     /translation="AVTGVVHLAARKQVAESVAQPTRYYRENVGGLATLLEAVAEAGVR
                     RFLFSSSAAVYGNPDVDLITEDTPCSPVNPYGETKLAGEWLVRAAGEAHGIATTCLRYF
                     NVAGAAEPALADT"
     CDS_motif       complement(2194..2280)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NFX46_RS12620_0001"
                     /evalue="1.40E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="NFX46_RS12620"
                     /protein_end="30"
                     /protein_start="1"
                     /score="17.8"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMTGAGERVVVL"
     misc_feature    2374..2388
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     gene            2583..4394
                     /locus_tag="NFX46_RS12625"
                     /old_locus_tag="NFX46_12625"
     CDS             2583..4394
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="NFX46_RS12625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12625"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_252548853.1"
                     /transl_table=11
                     /translation="MSTAILTGQPVPGSSIEADLRSLGFDVRTATDAADAETLLAAVPG
                     DQRVAVVDTRFVGHRHALRLGLTDPRFPLAAVPGAVTAQPAGRQALTRALARENSANGG
                     TVLAVDSLADRIVTALDADGGEVHRPELGSLVAAVPADPQARNEARQAVSAVDDEAVRL
                     KSAVKARDGFFTTFCISPYSRYLARWCARRGLTPNQVTTASLITALIAAGCAATGTRGG
                     YVAAGLLLLFSFVLDCTDGQLARYSLQYSTLGAWLDATFDRAKEYAYYAGLALGAARGG
                     DDVWALALGAMVLQTCRHVVDFSFNEANVDSTAATANTSPTAALSGKLDSVGWTVWARR
                     MIVLPIGERWAMIAVLTAATTPRITFYVLLVGCAFAATYTTAGRLLRSLTRKARRTDRA
                     AQALADLADSGPTAGLLVRFLPAGARPTATLSAAAGAVLVTLGAWLWGPSWWVVLMAGA
                     YVLLSAEAVARPLKGALDWLVPPVFRAAEYGTVLILAAKADVNGALPAAFGLVAAVAYH
                     HYDTVYRIRGNAGAPPAWLVRAVGGQEGRTLLVAVLAAVLTARQFTVALTVLAVAVALV
                     VLAESIRFWVAAHRAGAPSVHDEGEPA"
     gene            4391..5143
                     /locus_tag="NFX46_RS12630"
                     /old_locus_tag="NFX46_12630"
     CDS             4391..5143
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="NFX46_RS12630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12630"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_073495855.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.9e-10, bitscore:
                     39.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDSLPKALVPVGPAGIEGEPTVLDLTLG
                     NFAEIGLTEVAVIVGYRKEAVYERKAALEAKYGLKLTLIDNDKAEEWNNAYSLWCGRDA
                     LKDGVILANGDTVHPVSVERTLLAARGEGRKIILALDTVKSLADEEMKVVVDPAKGMTK
                     ITKLMDPAEATGEYIGVTLIEGDAAPELADALKTVWETDPQQFYEHGYQELVNRGFRID
                     VAPIGDVSWVEIDNHDDLARGREIACQY"
     gene            5131..6192
                     /locus_tag="NFX46_RS12635"
                     /old_locus_tag="NFX46_12635"
     CDS             5131..6192
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494151.1"
                     /locus_tag="NFX46_RS12635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12635"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_252548855.1"
                     /sec_met_domain="Fe-ADH (E-value: 9.2e-20, bitscore: 69.6,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.5e-07, bitscore:
                     29.7, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRPGALDDLVGVLADERISHSGKLAIAVSG
                     GSGARLRERLSPSLPGATWYEVGGGTLDDAVRLAGDIKAGHYDAVVGLGGGKIIDCAKF
                     AAARVGLALVAVPTNLAHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVIREAPVRY
                     VRAGIGDAVSNISAIADWELAHRVKGEKIDGLAAAIARQAGEAVLRHPGGIGDTGFLQV
                     LAEALVLSGIAMSVSGDSRPSSGACHEINHAFDLLYPKRAAAHGEQCGLGAAFAMYLRG
                     AHEESLYMAEVLRRHGLPVLPDEIGFTTDEFVKVVEFAPQTRPGRYTILEHLDLKTEQI
                     KDTYADYVKAIGS"
     gene            6170..6949
                     /locus_tag="NFX46_RS12640"
                     /old_locus_tag="NFX46_12640"
     CDS             6170..6949
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="NFX46_RS12640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12640"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_073495870.1"
                     /transl_table=11
                     /translation="MSRPSVAELRPVVHPAGVKDRRSGEHWMGRLYMREVSLRVDRYLV
                     NTRVTPNQLTYLMTVFGVLAAPALLVPGITGAVLGLVCVQMYLLLDCVDGEIARWKKQY
                     SLGGVYLDRVGAYLTDAAVLVGFGLRAADLWGTGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQGGLPPVKETASEPRSSGMALARRAAAALKFHRLVLGMEASLLILVLAIVDQ
                     TRGDLFFSRLGVAVLAGIALLQTVLHLVSILASSRLR"
     gene            6958..7839
                     /locus_tag="NFX46_RS12645"
                     /old_locus_tag="NFX46_12645"
     CDS             6958..7839
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="NFX46_RS12645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12645"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_252556375.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.1e-13,
                     bitscore: 47.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGAVIITMGNRPEELRALIDSVAKQDGDPVEVVVVGNGSPVPD
                     VTEFSTHVRTVELPENLGIPGGRNVGMEAFGPSGRDVDILMFLDDDGLLARHDTARLCR
                     EAFAADPELGIISFRIADPDTGVTQRRHVPRLRAADPMRSSRVTTFLGGANAVRTRVLA
                     EVGGLPDEFFYAHEETDLAWRALDAGWMIDYRSDMVLHHPTTAPSRHAVYHRMVARNRV
                     WLARRNLPAPLVPVYLGVWLLLTLLRRPSRSALKAWFGGFREGWATPCGPRRPMKWRTV
                     WRLTRLGRPPVI"
     gene            7936..8865
                     /locus_tag="NFX46_RS12650"
                     /old_locus_tag="NFX46_12650"
     CDS             7936..8865
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="NFX46_RS12650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12650"
                     /product="ABC transporter permease"
                     /protein_id="WP_073495860.1"
                     /transl_table=11
                     /translation="MSETTHDGAVAVSAPPSPDEGLTAAQLAAKYGLAVSGARPPLREY
                     VGRLWGRRHFILAFSQAKLTAQYSQAKLGQLWQVATPLLNAAVYFMIFGVILNASRGME
                     KEVYIPFLVTGVFVFTFTQSSVMSGVRAISGNLGLVRALHFPRAALPISFALQQLQQLL
                     YSMIVLFLVVIGFGSYPDASWILIVPALVLQFCFNTGLALVFARAGAKTPDLAQLMPFV
                     MRTWMYASGVMFSIPVFLADKPQWMANVLQWNPAAIYMDLVRFALIDEYGSENLPQHVW
                     AVAGGWAALFAIGGFVYFWQAEERYGRG"
     gene            8858..9640
                     /locus_tag="NFX46_RS12655"
                     /old_locus_tag="NFX46_12655"
     CDS             8858..9640
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330378.1"
                     /locus_tag="NFX46_RS12655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12655"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_252548857.1"
                     /transl_table=11
                     /translation="MAEQAPGTRVPTVIAEDVHIVYRVNGARTGKGSATAALSRIVKRG
                     GEERGVRKVHAVRGVSFVAHRGEAIGLIGSNGSGKSTLLRAIAGLLPPESGKVYTDGQP
                     SLLGVNAALMNDLTGERNIVLGGLAMGMSREQIKERYQEIVDFSGINEKGDFVTLPMRT
                     YSSGMQARLRFSIAAAKDHDVLMIDEALATGDAKFRKRSEERIRELRGQAGTVFLVSHS
                     NKSIRDTCDRVLWLERGELRMDGPTEEVLREYEKFSGK"
     gene            10001..10894
                     /gene="hpnC"
                     /locus_tag="NFX46_RS12660"
                     /old_locus_tag="NFX46_12660"
     CDS             10001..10894
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042802.1"
                     /locus_tag="NFX46_RS12660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12660"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_252556378.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 1e-39,
                     bitscore: 135.4, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 2.7e-38, bitscore:
                     130.6, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPGTADAERGTLAKAADENFPVAPFFLPRDWREDLVAVYGFAR
                     LVDDIGDGDLAPGGADARLLGVPADEAEDRLVLLDAFEADLRRVFDGTPRHPLLRRLRP
                     TVRRRSLTPEPFLGLIAANRQDQVVTRYETYDDLLAYCELSANPVGRLVLAVTGTTTPE
                     RVRLSDAICTALQIVEHLQDVAEDLGRDRVYLPAADMKRFHVQEADLAAVTAGASVRAL
                     VAFEAQRARDLLNEGAPLVGSVHGRLRLLLAGFVAGGRAALHAIAAAQHDVLPGPPKPG
                     KLRLLREVGVTLRGEG"
     gene            10891..11841
                     /gene="hpnD"
                     /locus_tag="NFX46_RS12665"
                     /old_locus_tag="NFX46_12665"
     CDS             10891..11841
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994383.1"
                     /locus_tag="NFX46_RS12665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12665"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_252548858.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.6e-54, bitscore:
                     182.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.6e-66,
                     bitscore: 223.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTVESPPPVSAPVLAAYGYCETVTGQQARNFAYGIRLLPTAKR
                     RAMSALYAFSRRVDDIGDGALDGEVKSARLQDTRALLTRVRAGEVEEDDTDPVAVALAH
                     SARVFPIPLGGLDELIDGVLMDVRGETYETWDDLRTYCRCVAGAIGRLSLGVFGTEAGA
                     RGADRAPEYADTLGLALQLTNILRDVREDALGGRTYLPADDLAKFGCSAGFDGPTPPEG
                     SDFAGLVHFEVRRARALFAEGYRLLPLLDRRSGACVAAMAGIYRRLLDRIERDPEAVLR
                     GRVSLPGREKAYVAVRGLSGLDTRHVSRLSGRRQI"
     gene            11841..11996
                     /locus_tag="NFX46_RS40615"
     CDS             11841..11996
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039420.3"
                     /locus_tag="NFX46_RS40615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6380 family protein"
                     /protein_id="WP_353850158.1"
                     /transl_table=11
                     /translation="MDPRGDNDVDQGDAAGEKRHATLRRGAASLTATARRAEFDRHGGR
                     TGEGAR"
     gene            11993..13450
                     /gene="hpnE"
                     /locus_tag="NFX46_RS12670"
                     /old_locus_tag="NFX46_12670"
     CDS             11993..13450
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994384.1"
                     /locus_tag="NFX46_RS12670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12670"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_252548860.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.2e-06, bitscore:
                     26.9, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 8.6e-09, bitscore: 34.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDEPRSDIPETSGRDAVVIGGGLAGITAALTLADAGVRVTLLES
                     RPRLGGLAFSFQRDGLTVDNGQHVYLRCCTAYRWFLDRIEGTALAPIQNRLDVPVVDLA
                     KPEGRRLGRLRRDALPVPLHLGRSLATYPHLSLADRARVGRAALALKGLDLADPALDAQ
                     DFGSWLTAHGQSARAVEALWDLVGVATLNAVAGDTSLALAAMVFKTGLLSDPGAADIGW
                     AHVPLGELHDRLARKALDSAGVRTEIRTRVTSVSAEDNGSWTVQVPGETLRADAVVLAV
                     PQRETYDLLPDGALDAPERLLDIGTAPILNLHVVYDRKVLDVPFLTALGTPVQWVFDRT
                     DASGLSTGRPEGPDEGRGGRRSGQYLAVSQSAAHEDIDAPVAALRERYLPELERLLPAA
                     RGATVRDFFVTRERTATFAPTPGVGRLRPGARTKASGLYLAGAWTATGWPATMESAVRS
                     GVSAADAALGALGRPRPRRLFAVEEAA"
     gene            13525..14589
                     /locus_tag="NFX46_RS12675"
                     /old_locus_tag="NFX46_12675"
     CDS             13525..14589
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972234.1"
                     /locus_tag="NFX46_RS12675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12675"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_252556381.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-57, bitscore:
                     194.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPAEKAARRTAVDVTALLERGRTLATPVLRAAVDRLVSPMDTVA
                     AYHFGWIDAQGNPTDGDGGKAVRPALAVLSAQVTGAAPEVGVPGAVAVELVHNFSLLHD
                     DLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALAGEVLLELGTVEAGRAARRLTTASR
                     ALIDGQAQDMSYEHRDRVSVEECLEMEGNKTGALLACASSIGAVLGGADARTADTLERY
                     GHHLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRKKSLPVVAALAAGGPASEQLGEML
                     AADAKRQDFANFSEEEFAARAALIEEAGGREWTAGEARRQHTVAIEALNAVDMPEQVRD
                     QFTALADFVVVRKR"
     gene            14709..16721
                     /gene="shc"
                     /locus_tag="NFX46_RS12680"
                     /old_locus_tag="NFX46_12680"
     CDS             14709..16721
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019985322.1"
                     /locus_tag="NFX46_RS12680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12680"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_252548862.1"
                     /sec_met_domain="T2TS (E-value: 4.6e-146, bitscore: 486.4,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGALPPRAAAASETRIDIPAAAGVQEAAVRAVQRATD
                     FLLARQDVEGWWKGDLETNVTMDAEDLLLRQFLDIQDESTTRAAALFIRGEQRGDGTWA
                     TFHGGPGDLSATIEAYVALRLAGDEPHAPHMAKASAWVRDQGGIAAARVFTRIWLALFG
                     WWKWEDLPELPPELLYFPKWFPLSIYNFGCWARQTIVPLTVVSAKRPVRPAPFPLDELH
                     TDPADPNPPRPLAPVASWDGLFQRLDKVVRGYRKVAVRRLRKAALNSAARWIVERQEND
                     GCWGGIQPPAVYSVIALYLLGYDLEHPVMREGLKSLDRYAVWREDGARMIEACQSPVWD
                     TCLATIALADAGVPADHPKLVKAADWMLGEQIVRPGDWSVRRPGLPPGGWAFEFHNDNY
                     PDIDDTAEVVLALRRVRHHDPDRVESAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNR
                     LPFCDFGEVIDPPSADVTAHVVEMLAFEGLSHDPRTRRGITWLLAEQEPEGSWFGRWGV
                     NYIYGTGSVVPALTAAGLPARHPAIRRAVGWLERVQNEDGGWGEDLRSYQDSTRWSGRG
                     ASTASQTAWALMALLAAGEKDSKAVERGVAWLAETQREDGSWDEPQFTGTGFPWDFSIN
                     YHLYRQVFPLTALGRYVHGEPLVVKAPSPAEAEGR"
     gene            16721..17362
                     /locus_tag="NFX46_RS12685"
                     /old_locus_tag="NFX46_12685"
     CDS             16721..17362
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431357.1"
                     /locus_tag="NFX46_RS12685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12685"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_252548864.1"
                     /transl_table=11
                     /translation="MNAQPASAPLLIACALGIEHLALRMGDRGGAGGPVTVLRTGMGPK
                     AAERSVTRVLADPVLGGAAVLATGFCAGLAPGMHPGDLVVAEETRDPLGTVPCVNTDLL
                     VKELVRTLPGRTVHTGPLTGSDHVVRGPERSDLLATGAIAVDMESAATLLSAVRAGTRP
                     VAAVRVVVDAPEHELVRIGTVRGGISAFRVLRSVLPAFFEWHRNVLLPRR"
     gene            17368..18390
                     /gene="hpnH"
                     /locus_tag="NFX46_RS12690"
                     /old_locus_tag="NFX46_12690"
     CDS             17368..18390
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386169.1"
                     /locus_tag="NFX46_RS12690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12690"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_252548866.1"
                     /sec_met_domain="PF04055 (E-value: 1.5e-17, bitscore: 63.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2.2e-08, bitscore: 32.7,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIKVATYLAEQKLRKREKFPLIVELEPLFACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIHEIVRQLVARKKYVF
                     LCTNAMLMRKKMDRFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAIKEAKRRGF
                     RVTTNSTFFNTDTPQTIIEVLNFLNDDLKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFSGGNRRRWRLNHSPLFLDFLEGKVDFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELIEETDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAMRETVSGNRD
                     "
     gene            18395..19552
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="NFX46_RS12695"
                     /old_locus_tag="NFX46_12695"
     CDS             18395..19552
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031167.1"
                     /locus_tag="NFX46_RS12695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12695"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_252548868.1"
                     /transl_table=11
                     /translation="MTAISLGIPEVPVRPIAARRVSRRIQVGPVAVGGGAPVSVQSMTT
                     TRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALATIARKSQIPVIADIHFQPKYV
                     FAAIEAGCAAVRVNPGNIKQFDDKVKEIAKAANEHGTPIRIGVNAGSLDRRLLQKYGKA
                     TPEALVESALWEASLFEEHDFRDIKISVKHNDPVVMVEAYRQLAAQCDYPLHLGVTEAG
                     PAFQGTIKSAVAFGALLSQGIGDTIRVSLSAPPAEEVKVGIQILESLNLRQRGLEIVSC
                     PSCGRAQVDVYKLAEEVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQI
                     FVKGEVVKTVPESRIVETLIEEAMKIAQRMEQDGVASGGPAVTVS"
     gene            19581..21482
                     /gene="dxs"
                     /locus_tag="NFX46_RS12700"
                     /old_locus_tag="NFX46_12700"
     CDS             19581..21482
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386171.1"
                     /locus_tag="NFX46_RS12700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12700"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_252548870.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.2e-109,
                     bitscore: 364.6, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.7e-06, bitscore:
                     24.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILENIRQPRDLKALSEVELGELCCEIREFLVHAVARTGGHLGP
                     NLGVVELTVALHRAFESPVDRILWDTGHQSYVHKLLTGRQDFSKLRGKGGLSGYPSREE
                     SEHDVIENSHASTALGWADGLAKARQVRGEKGHVVAVVGDGALTGGMAWEALNNIAAAK
                     DRPLIIVVNDNERSYAPTIGGLADHLATLRTTDGYEKVLAWGKDVLLRTPVVGHTVYES
                     LHGAKKGFKDAFAPQGMFEDLGLKYVGPVDGHDIGAVESALRRAKRFHGPVLVHCLTEK
                     GRGYEPALAHEEDHFHTVGVMDPLTCAPLAPAGAPSWTSVFGDEIVRIGEERDDVVAIT
                     AAMLHPVGLGEFAARFPGRVWDVGIAEQHAAVSAAGLATGGLHPVVAVYATFLNRAFDQ
                     LLMDVALHRCGVTFVLDRAGVTGVDGASHNGMWDMSVLQVVPGLRIAAPRDADQLRAQL
                     REAVAVDDAPTLIRFPKESVGPRIPAVGHVGGMDVLHRGAAPEVLLVAVGVMAPACLRA
                     AELLEARGIDCTVVDPRWVKPVDPALPGLAAEHRLVAVVEDNSRAAGVGSAVALALGDA
                     EVDVPVRRFGIPEQFLAHAKRAEVLADIGLTPVEIAGRISASLAVRDAGGPVKETTQ"
     misc_feature    19587..19601
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.87"
                     /tool="antismash"
     gene            21479..22864
                     /locus_tag="NFX46_RS12705"
                     /old_locus_tag="NFX46_12705"
     CDS             21479..22864
                     /NRPS_PKS="Domain: Aminotran_3 (41-363). E-value: 1e-88.
                     Score: 289.5. Matches aSDomain:
                     nrpspksdomains_NFX46_RS12705_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494124.1"
                     /locus_tag="NFX46_RS12705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12705"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_252548872.1"
                     /sec_met_domain="Aminotran_3 (E-value: 5.1e-86, bitscore:
                     287.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTEFDLGALLAERGAERYELHARYLNHQLPRMLHTIGFDKVYER
                     GEGAYFWDADGNDYLDMLAGFGVMGLGRHHPVVRKALHDVLDASLADLTRFDCQPLPGL
                     LAEKLLAHSPHLDRVFFGNSGTEAVETALKFARYATGKPRVLYCDHAFHGLTTGSLSVN
                     GEGGFRDGFAPLLPDTAVPLGDLDALARELRKGDVAALIVEPIQGKGVHEAPPGYLRAA
                     QELLHRHRALLIADEVQTGLGRTGDFYAYQHEDGVEPDLVCVAKALSGGYVPVGATLGK
                     DWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMENEQIVAGARLTGDLLKSRLT
                     ALIDKYELLADVRGRGLMIGIEFGKPRSLKLRSRWAMLQAARKGLFAQMVVVPLLQRHR
                     ILTQVSGDHLEVIKLIPPLVVGEPEVNRFVDAFTEVMDDAHNGGGLVWDFGRTLIKQAV
                     ANR"
     aSDomain        21602..22567
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NFX46_RS12705_Aminotran_3.1"
                     /evalue="1.00E-88"
                     /label="NFX46_RS12705_Aminotran_3.1"
                     /locus_tag="NFX46_RS12705"
                     /protein_end="363"
                     /protein_start="41"
                     /score="289.5"
                     /tool="antismash"
                     /translation="VYERGEGAYFWDADGNDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DASLADLTRFDCQPLPGLLAEKLLAHSPHLDRVFFGNSGTEAVETALKFARYATGKPRV
                     LYCDHAFHGLTTGSLSVNGEGGFRDGFAPLLPDTAVPLGDLDALARELRKGDVAALIVE
                     PIQGKGVHEAPPGYLRAAQELLHRHRALLIADEVQTGLGRTGDFYAYQHEDGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMENE
                     QIVAGARLTGDLLKSRLTALIDKYELLADVRGRGLMIGIEF"
     misc_feature    22880..22895
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.09"
                     /tool="antismash"
     misc_feature    22920..22940
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     gene            22946..23569
                     /locus_tag="NFX46_RS12710"
                     /old_locus_tag="NFX46_12710"
     CDS             22946..23569
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133819.1"
                     /locus_tag="NFX46_RS12710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12710"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_073499747.1"
                     /transl_table=11
                     /translation="MSHPASEPGPEPADDLGVVAPQLRALRRRASLTLEAAARAAGLSP
                     AHLSRLETGQRQPSLPMLLALARVYGTTVSELLGERVADRDAVVRAADMEPTHAGGWTY
                     WQSGASGRGMQALRVQVPYGSQGDIVRVHPGEEWLHVLRGRLRLRLGDTTHLLGAGDSA
                     HFDSLTPHRIAAQDPDGVDLLFVHTLLQSPTAALCLGPTPGETP"
     gene            23566..23688
                     /locus_tag="NFX46_RS12715"
                     /old_locus_tag="NFX46_12715"
     CDS             23566..23688
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009329167.1"
                     /locus_tag="NFX46_RS12715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12715"
                     /product="DUF6126 family protein"
                     /protein_id="WP_073499749.1"
                     /transl_table=11
                     /translation="MTDIEEKFPRSLWIRLIIYIAVGHVFAGFLWLLFEVGAKR"
     gene            complement(23715..24512)
                     /locus_tag="NFX46_RS12720"
                     /old_locus_tag="NFX46_12720"
     CDS             complement(23715..24512)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="NFX46_RS12720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_12720"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_252548874.1"
                     /transl_table=11
                     /translation="MTQQIPSTEPELAGVRNFRDVGGLPTVDGRRVRHGVLFRSGHLAH
                     ATDEDVAFLSSLGLHTVFDFRNAADQKLEGPDVELPGVRNVNLPLSDPADGAEFWKMVR
                     EGDIEQLREILGDGRAAGRMIASYRSIMKERTGEHSRVLHSLAEDSVPALMHCAAGKDR
                     AGLSIAVTLLALGVERDAILADYLESSAKHRRYKVRRSGTSAAAYSPEVMELLDPLFDA
                     RAEYLTAAFETVEETWGGVDTYLEQGLGLTPRTRERLRERLLD"
     misc_feature    complement(24765..24778)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     misc_feature    complement(25505..25518)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.75"
                     /tool="antismash"
     regulatory      25644..25801
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(25807..25822)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.08"
                     /tool="antismash"
ORIGIN
        1 cggtggcagg tgtgatcggc atacccatcc ttaacatcgg tcctcgcgcc cccagtctgc
       61 cgtacgcgca cggcactccc ggcacttccg cgcgcacgcc cgcatgtccc gccgcccggc
      121 gcgaccacgg ccgccgccac ccggtctccg gaaacggggc ccggtgggtg atcttgcccg
      181 gcgccgcgcg cccggaaccg tccggaacgc atgtgcgaac ccggtgccgc ccggccggtc
      241 agtggcagag ccgtgcctcg tgctgcgcgt gcccgctcgg ctccagctgg aaggtgcagt
      301 gcgccacgtc gaagtgatcg cccagacagc cctggagctc gtgcagcatc ttctcgtggc
      361 cgatcgcgtc cagcacgtcg gaacgcacca ccacgtgcgc cgacagcacc ggcatgccgg
      421 aggtgatcgt ccaggcgtgc aggtcgtgca cgtcctccac gccgtccagg gcgagcatgt
      481 gggtgcgcac ctccgccatg tcgacgccct tcggagccgc ctccagcagc acgtccagcg
      541 tctcgcgcag cagcttcacc gtccggggca cgatcatcag gccgatgacg agcgaggcga
      601 ccgggtcggc ggcctgccag ccggtcgtca ggatcaccac cgccgagacc agcaccgcga
      661 ccgagcccag cgcgtccgcc gccacctcaa ggaaagcgcc ccgcacgttg atgctgtccg
      721 cctggccgcg catcagcagg ctcagcgaga ccatgttggc ggccaggccg atcccaccga
      781 acacgatcat cagcccgccc tcggtcgggg ccggcgtgaa gaaccgctgg acggcctcgt
      841 acacgacgta cccgcccacg ccgagcagca gcagacagtt ggcgagcgcg gccaggatct
      901 cggcgcgggc gtacccgaag gtgcggttcc cggtcggcgg gcggcccgcg aagtggatgg
      961 cgagcagcgc catgcccagg ccgagggcgt cggtcgccat gtgcgccgcg tcggcgatca
     1021 gggcgaggga gtcggcgagc acaccgccga cgatctccac caccatgacg gtgagcgtga
     1081 tcgagagcgc ggcgcgcagt ctgccgcggt acgccgccgc ggccgtaccc gtggtcggca
     1141 cgtgcgtgtg gccgtggtcg tgcccagccc ccatgagaaa cagcctcctg tgatccgccc
     1201 gggctcccag tgaactacgg gtggggggta tccggcaacg cggcactgaa caccgttgtc
     1261 atgtgccctg acctgcgaaa acgaaatgca ggtcagcggc ctggcgccgg ctcacccgcc
     1321 gtggtgcagc tgccatcccc gccaggccga cgcgaccatc tcgcgcatcc cgcgcgaggc
     1381 ggtccagccc agttcccggg cggccagcgc ggccgaggcc accgcgcgcg gggcgtcccc
     1441 ggggcgtcgt ccctcgacca gggcgggccg ggggtcgccg gtgaccttgc cgatcagcgt
     1501 gaccagctcg cgcaccgaga ctccctcgcc ccggccgatg ttcaccgtca gatcgccgcg
     1561 cacgtccggc gcggtgagcc gccgggccgc cgcgagatgc gcctcggcca ggtcggcgac
     1621 gtggatgtag tcccgtacac aggtgccgtc cggcgtcggg tagtcgtcgc cgaagatccg
     1681 gggggcctcg tcgcgggtga gccggtcgaa gaccatcggg acgatgttga agacgccggt
     1741 gtcggccagg gcgggctcgg ccgccccggc cacgttgaag tagcgcaggc acgtcgtcgc
     1801 gatgccgtgc gcctcgcccg ccgcccgcac cagccactcc ccggcgagct tggtctcgcc
     1861 gtacgggttg accggggagc agggggtgtc ctccgtgatg aggtccacgt ccgggttgcc
     1921 gtacacggcc gccgacgagg agaacaggaa ccggcggaca ccggcctcgg cgaccgcctc
     1981 cagcagggtg gccagaccgc cgacgttctc ccggtagtag cgcgtgggct gcgccaccga
     2041 ctcggcgacc tgcttgcgcg ccgccaggtg caccaccccg gtcaccgcgt gctcggccag
     2101 cacccgcttc agcagccccg cgtcgagcgc cgagcccgcc acgagcggca cgtccgcggg
     2161 cagccggccg ggcacgccgg ccgacaggtc gtccaggacg acgacgcgct cgccggcgcc
     2221 ggtcatggcc cgcgccacat gtgcccctat gtatccggcc ccgccggtga tcagccacgt
     2281 catggccgcc caccctatgc cgagccccca ggtccgtgcg caatgtcccg gatgtccgcc
     2341 accggggagc gcggtttgtg ggcggggccg ccgatcacac atgatgatct cggcgacggc
     2401 cggtccggac cgtgtggatc ggacctgaac ggccggtgaa cacggccttc ccggcatccg
     2461 atagcctctg ccgaatgccg cgcccggtgc cctcaccggt gccgccaagg ggcgcccgcc
     2521 atgcagagcc caccatgcag acgaccggcg cgcacgcgcc gggacccagg gagtgagttc
     2581 ggttgtcgac cgccatcctc accggtcagc cggtccccgg ttcgtcgatc gaggcagacc
     2641 tgcggtccct cggcttcgac gtccggaccg ccaccgatgc cgccgacgcg gagacgctcc
     2701 tcgcggccgt cccgggtgac cagcgggtcg ccgtcgtcga cacccgcttc gtgggccatc
     2761 gccacgcgct gcgcctcggc ctcaccgacc cccgcttccc gctcgccgcg gtccccggcg
     2821 ccgtcaccgc gcagccggcc ggccggcagg ccctgacccg cgccctggcc cgcgagaact
     2881 cggcgaacgg cggcaccgtc ctcgccgtgg acagcctcgc cgaccgcatc gtcaccgccc
     2941 tcgacgccga cggcggcgag gtgcaccggc ccgagctggg cagcctggtc gccgccgtcc
     3001 cggccgaccc gcaggcccgc aacgaggcac ggcaggccgt cagcgccgtc gacgacgagg
     3061 ccgtacgcct gaagtcggcc gtgaaggccc gcgacggctt cttcacgacg ttctgcatca
     3121 gcccctactc gcgctacctc gcccgctggt gcgcccgccg ggggctcacc cccaaccagg
     3181 tcaccaccgc ctcgctgatc accgcgctga tcgcggcggg ctgcgcggcc accggcaccc
     3241 gcggcggata cgtcgccgcc ggactgctgc tcctcttctc cttcgtgctg gactgcaccg
     3301 acggccagct cgcccgctac tccctccagt actccaccct cggagcctgg ctggacgcca
     3361 ccttcgaccg ggccaaggag tacgcctact acgccggact cgccctcgga gcggcgcgcg
     3421 gcggcgacga cgtctgggcc ctggccctcg gcgcgatggt cctccagacc tgccggcacg
     3481 tcgtggactt ctccttcaac gaggcgaacg tcgacagcac cgccgccacc gcgaacacca
     3541 gtcccaccgc ggccctctcc ggcaagctgg acagcgtcgg ctggacggtc tgggcgcgcc
     3601 ggatgatagt cctgcccatc ggcgaacgat gggccatgat cgccgtcctc accgcggcca
     3661 ccaccccccg catcaccttc tacgtcctgc tcgtcggctg cgccttcgcc gcgacgtaca
     3721 ccacggcggg ccgcctcctg cgctccctca cccgcaaggc gcggcgcacg gaccgggccg
     3781 cgcaggcctt ggcggacctc gcggacagcg ggccgacggc cggtctgctg gtccggttcc
     3841 tgcccgccgg ggcgcggccg acggcgaccc tcagcgccgc cgccggtgcc gtgctcgtca
     3901 cgctcggcgc ctggctgtgg ggaccgagct ggtgggtcgt gctgatggcc ggcgcctatg
     3961 tcctgctgtc cgccgaagcc gtcgcccgcc ccctcaaggg cgccctcgac tggctcgtgc
     4021 cgccggtgtt ccgcgccgcc gagtacggca cggtgctgat cctcgcggcg aaggcggatg
     4081 tgaacggagc gctaccggcg gctttcgggc tggttgccgc cgtcgcctac catcactacg
     4141 acacggtgta ccgcatccgc ggcaacgccg gagcgccgcc ggcctggctg gtgcgcgctg
     4201 tcgggggaca ggaggggcgg acgctgctcg tggccgtact ggccgcggtg ctcaccgccc
     4261 ggcagttcac ggtcgcgctc acggtgctcg ccgtggccgt cgccctcgtg gtgctcgccg
     4321 agagcatccg cttctgggtc gccgcccacc gggcaggcgc cccgtccgta cacgatgaag
     4381 gagaacccgc atgatcggcc tcgtgctggc ggccggcgcc ggacggcgtc tgcgccccta
     4441 caccgacagc ctgcccaagg cgctggtgcc ggtggggccc gcgggcatag agggcgagcc
     4501 cacggtgctg gacctgaccc tcggcaactt cgccgagatc ggtctgaccg aggtcgcggt
     4561 catcgtcggc taccgcaagg aagccgtgta cgagcgcaag gcggccctgg aggcgaagta
     4621 cggcctcaag ctgaccctca tcgacaacga caaggccgag gagtggaaca acgcctactc
     4681 cctgtggtgc gggcgtgacg ccctcaagga cggtgtgatc ctcgccaacg gcgacaccgt
     4741 gcacccggtc tccgtcgaga ggaccctgct cgccgcccgc ggcgagggca ggaagatcat
     4801 cctcgccctc gacaccgtga agtccctcgc ggacgaggag atgaaggtcg tcgtcgaccc
     4861 cgcgaagggc atgacgaaga tcaccaagct gatggacccc gccgaggcca ccggcgagta
     4921 catcggcgtc accctcatcg agggcgacgc cgcccccgaa ctggccgacg cgctgaagac
     4981 cgtgtgggag accgacccgc agcagttcta cgagcacggc taccaggaac tggtgaaccg
     5041 aggcttccgg atcgacgtgg ccccgatcgg cgacgtcagc tgggtcgaga tcgacaacca
     5101 cgacgatctc gcccgtggac gggagatcgc gtgccagtac tgacccggct gatcccctcg
     5161 ccggtcgtcg tcgacatccg tccgggtgcc ctcgacgacc tcgtcggggt cctcgccgac
     5221 gagcgcatct cgcactcggg caagctcgcg atcgccgtca gcggcggctc gggcgcccgg
     5281 ctgcgcgagc gcctctcccc ctccctgccc ggcgccacct ggtacgaggt cggcggcggc
     5341 accctcgacg acgccgtgcg gctcgccggt gacataaagg ccggccacta cgacgcggtc
     5401 gtgggcctgg gcggcggcaa gatcatcgac tgcgccaagt tcgccgcggc acgggtgggc
     5461 ctcgcgctcg tcgccgtacc gacgaacctc gcgcacgacg gcctgtgctc cccggtcgcc
     5521 actctcgaca acgacgcggg ccgcggctcc tacggggtgc cgaacccgat cgcggtcgtg
     5581 atcgacctgg acgtcatccg cgaggcaccg gtgcgctacg tgcgggccgg catcggcgac
     5641 gccgtctcca acatctccgc gatcgccgac tgggagctgg cccaccgcgt caagggcgag
     5701 aagatcgacg gcctcgccgc cgcgatcgcc cggcaggcgg gcgaggcggt cctcaggcac
     5761 ccgggcggca tcggcgacac cggcttcctc caggtgctcg ccgaggcact cgtcctcagc
     5821 ggcatcgcga tgtcggtgtc cggcgactcc cgcccctcct ccggcgcctg ccacgagatc
     5881 aaccacgcct tcgacctgct gtatcccaag cgtgccgccg cccacggcga gcagtgcgga
     5941 ctcggcgcgg ccttcgcgat gtacctgcgc ggagcccacg aggagtccct ctacatggcc
     6001 gaggtgctgc gccggcacgg gctgccggtg ctgcccgacg agatcggctt cacgaccgac
     6061 gagttcgtca aggtcgtcga gttcgccccg cagacccgcc ccggccgcta cacgatcctc
     6121 gaacacctcg acctcaagac cgaacagatc aaggacacct acgccgacta tgtcaaggcc
     6181 atcggtagct gaactcagac cggtcgtcca ccccgcgggg gtgaaggacc ggcgcagcgg
     6241 tgagcactgg atgggacgcc tctacatgcg tgaggtgtcc ctgcgggtcg accgctacct
     6301 ggtcaacacc agggtcacgc ccaaccagct cacgtacctg atgaccgtct tcggtgtgct
     6361 cgcggccccg gccctgctgg tgccggggat cacgggcgcc gtgctcggcc tggtctgcgt
     6421 ccagatgtac ctgctgctgg actgcgtgga cggcgagatc gcccgctgga agaagcagta
     6481 ctcgctcggc ggtgtctacc tcgaccgggt cggggcctac ctgaccgacg ccgcggtgct
     6541 cgtcggcttc ggccttcgcg ccgccgacct gtggggcacc ggccgtatcg actggctgtg
     6601 ggccttcctc ggcaccctgg ccgcgctcgg cgccatcctg atcaaggcgg agaccgatct
     6661 cgtcggcgtc gcccgccacc agggcggact gccgccggtc aaggagacgg cgtccgagcc
     6721 gcgctcctcc ggcatggcgc tggcccgccg ggccgccgcc gcgctcaagt tccaccgcct
     6781 ggtcctcggg atggaggcct cgctgctcat cctggtcctg gcgatcgtgg accagacgcg
     6841 cggggacctc ttcttctccc ggctcggcgt cgccgtactc gccggcatcg cactgctcca
     6901 gaccgtgctg cacctggtgt ccatcctcgc gtcgagcagg ctgcggtgag cgcgcccatg
     6961 aaggtcggcg cggtgatcat caccatgggc aaccggcccg aggaactgcg cgcgctgatc
     7021 gactcggtcg ccaagcagga cggcgacccg gtcgaggtcg tcgtggtcgg caacggctcc
     7081 ccggtcccgg acgtcaccga gttctccacg cacgtgcgca ccgtcgagct gcccgagaac
     7141 ctcggcatcc ccggcggccg caacgtcggc atggaggcct tcggccccag cggccgcgac
     7201 gtcgacatat tgatgttcct cgacgacgac gggctgctcg cccggcacga caccgcccgg
     7261 ctgtgccgcg aggccttcgc ggccgacccc gagctgggca tcatcagctt ccgcatcgcc
     7321 gaccccgata ccggggtcac ccagcgccgc cacgtgcccc ggctgcgcgc cgccgacccg
     7381 atgcgctcct cccgggtcac caccttcctc ggcggcgcca acgcggtgcg cacccgggtc
     7441 ctcgcggagg tcggcggtct cccggacgaa ttcttctacg cccacgagga aaccgacctg
     7501 gcatggcggg ccctcgacgc gggctggatg atcgactacc ggtccgacat ggtgctgcac
     7561 cacccgacga ccgcgccctc gcggcacgcg gtctaccacc gcatggtcgc ccgcaaccgg
     7621 gtctggctgg cccggcgcaa cctccccgcg cccctcgtcc cggtctacct cggggtctgg
     7681 ttgctgctca ctctgctgcg ccgcccctcg cgctcggccc tgaaggcgtg gttcggtggt
     7741 ttccgggaag ggtgggccac accgtgcgga ccgcgcaggc ccatgaagtg gcgtacggtg
     7801 tggcggctga cccgactggg ccggcctccc gtcatctgac aagctcgtcc ccgagggccc
     7861 gggccgttcc gcggcccccc ggcacgtgcc ggcccggttc aggccgcgca tcccgaagac
     7921 gaaagtttcc tactggtgag tgagacaacg catgacggcg cagtcgcggt gagtgcgccg
     7981 ccgtcgcccg acgagggcct cacggcggcg cagctggccg ccaagtacgg gttggccgtg
     8041 agcggtgccc ggcccccgct gcgggagtac gtcggccggc tctggggacg ccgtcacttc
     8101 atcctggcct tctcccaggc gaagctgacc gcccagtaca gccaggccaa gctggggcag
     8161 ctgtggcagg tggccacacc gctgctgaac gccgccgtgt acttcatgat cttcggcgtg
     8221 atcctcaacg ccagccgcgg catggagaag gaggtgtaca tcccgttcct cgtcacgggt
     8281 gtgttcgtct tcaccttcac ccagtcctcg gtgatgagcg gcgtccgcgc gatctccggc
     8341 aacctcggcc tggtccgcgc cctgcacttc ccgcgggccg cgctgccgat ctccttcgcg
     8401 ctccagcagc tccagcagct gctgtactcg atgatcgtgc tgttcctggt ggtgatcggt
     8461 ttcggcagct acccggacgc ctcctggatc ctgatcgtcc cggcgctggt gctccagttc
     8521 tgcttcaaca ccggtctggc actggtgttc gcacgggccg gcgccaagac cccggacctg
     8581 gcgcagctga tgccgttcgt gatgcggacc tggatgtacg cctccggcgt catgttctcc
     8641 atccccgtct tcctcgccga caagccgcag tggatggcga acgtcctgca gtggaacccg
     8701 gccgccatct acatggacct ggtgcgcttc gccctcatcg acgagtacgg ctccgagaac
     8761 ctgccccagc acgtgtgggc cgtcgccggc ggctgggccg cgctgttcgc gatcggcggc
     8821 ttcgtctact tctggcaggc ggaggagagg tacggccgtg gctgagcagg cgccgggcac
     8881 ccgggtcccc accgtcatcg ccgaggacgt gcacatcgtc taccgcgtca acggcgcccg
     8941 gacggggaag ggcagcgcca ccgcggccct cagccggatc gtcaaacgcg gcggcgagga
     9001 gcggggcgtg cgcaaggtgc acgcggtacg cggcgtctcc ttcgtcgccc accgcggcga
     9061 ggccatcggc ctgatcggct ccaacggctc cggcaagtcc accctgctgc gcgccatcgc
     9121 cggcctgctg ccgcccgaga gcggcaaggt ctacaccgac ggccagccct cgctgctcgg
     9181 cgtgaacgcc gccctgatga acgacctgac cggcgagcgc aacatcgtgc tcggcgggct
     9241 cgccatgggc atgtcccggg agcagatcaa ggagcgctac caggagatcg tcgacttctc
     9301 cggcatcaac gagaagggcg acttcgtcac cctgcccatg cgcacctact cctccggcat
     9361 gcaggcccgt ctgcggttct ccatcgccgc ggccaaggac cacgacgtcc tgatgatcga
     9421 cgaggcgctg gccaccggcg acgcgaagtt ccgcaagcgc tccgaggaac gcatccggga
     9481 gctgcgcggg caggccggga cggtgttcct ggtcagccac agcaacaagt cgatccggga
     9541 cacctgcgac cgcgtgctgt ggctggagcg cggtgagctg cgcatggacg gaccgaccga
     9601 agaggtcctg cgggagtacg agaagttctc cgggaagtga cccggtgccg tcggggcccc
     9661 gccggaactg tccggcgggg ccccgcgtct gcaaaggagg cgtcaactcc tgcccgccgt
     9721 aggaagcttg acgccgatcg gtgtgttgtt gtgatctgcg ggacacccgg gcgtacctcg
     9781 ccgcgttgta caacgtaagc tgtggcgggt cccgaaacgc gtcaagtggg gcgataatgc
     9841 gcgacacctc cgggcacggc tgccacgcgg gcggccgggc ggcgtgtccg aaatagtggg
     9901 tgtcgggttg tcggtgtaga acgggagatg tgacggcaat ggctacggaa actccccagc
     9961 tcaacgcagc atgcgccgtc cctgccccgg gcagccgacg atgacggcgc cgggcaccgc
    10021 ggacgcggag cgcggcaccc tcgccaaggc cgccgacgag aacttccccg tggccccctt
    10081 cttcctgccc cgggactggc gcgaggacct ggtggccgtg tacggcttcg cccgcctcgt
    10141 cgacgacatc ggtgacggcg acctggcacc cggcggcgcc gacgcccgcc tgctgggcgt
    10201 gccggccgac gaggccgagg accgcctggt cctcctcgac gccttcgagg ccgacctgcg
    10261 gcgcgtcttc gacggcacgc cccgccaccc cctgctgcgt cgcctgaggc ccaccgtgcg
    10321 ccgccgctcg ctcacccccg agcccttcct cggcctgatc gccgccaacc gccaggacca
    10381 ggtcgtcacc cggtacgaga cctacgacga cctgctggcc tactgcgagc tgtccgccaa
    10441 ccccgtgggc cgcctggtcc tcgccgtcac cggcaccacg acccccgagc gcgtccgcct
    10501 ctccgacgcg atctgcaccg cgctccagat cgtcgagcac ctccaggacg tggccgagga
    10561 cctcggccgc gaccgtgtct accttcccgc cgcggacatg aagcgttttc acgtccagga
    10621 ggcggatctc gcagcggtca ccgcgggcgc gtcggtgcgc gccctggtcg ccttcgaagc
    10681 ccaacgcgcc cgcgacctcc tgaatgaagg cgcccccctc gtgggtagcg tccacggcag
    10741 gctgaggctg ctgctcgcgg gcttcgtggc gggaggaagg gcggcgctcc acgcgatcgc
    10801 cgccgcccag cacgacgttc ttcccggccc gcccaagccc ggcaagctcc ggctgctgcg
    10861 cgaggtgggc gtgaccctgc gaggagaggg gtgatccgga ccgtggagtc accgccaccc
    10921 gtgtccgcgc cggtactcgc cgcctacggc tactgcgaga ccgtcacggg ccaacaggcg
    10981 cgcaacttcg cctacggcat ccggctgctg cccaccgcga agcggcgtgc gatgtcggcg
    11041 ctgtacgcgt tctcgcgccg cgtcgacgac atcggcgacg gcgcgctgga cggcgaggtc
    11101 aagagcgccc ggctccagga cacgcgggcg ctgctcaccc gggtccgcgc gggcgaggtc
    11161 gaggaggacg acaccgaccc cgtcgcggtc gccctcgcgc actccgcgcg ggtcttcccg
    11221 atcccgctgg gcggcctgga cgagctgatc gacggcgtcc tgatggacgt ccgcggcgag
    11281 acctacgaga cctgggacga cctgaggacg tactgccgct gcgtggcggg cgccatcggg
    11341 cggctctccc tgggcgtgtt cggcacggaa gcgggggcgc gcggcgccga ccgggcgccg
    11401 gagtacgccg acaccctcgg cctcgccctc caactgacca acatcctcag ggacgtccgc
    11461 gaggacgccc tcggcgggcg tacctatctg cccgccgacg acctcgccaa gttcggctgc
    11521 tcggccgggt tcgacgggcc gacgccgccg gagggctccg acttcgcggg cctcgtgcac
    11581 ttcgaggtgc gacgcgcccg cgccctgttc gccgagggct accggctgct tcccctgctc
    11641 gaccggcgca gcggcgcctg tgtggccgcg atggccggca tctaccgccg cctcctcgac
    11701 cgcatcgagc gcgaccccga ggccgtcctg cgcggccggg tctcgctgcc cggccgggag
    11761 aaggcctacg tcgccgtccg cggcctctcc ggtctggaca cccgccatgt gtcccggctg
    11821 tccggcagga ggcagatctg atggacccac ggggtgacaa cgacgtggac cagggcgatg
    11881 ccgccggaga aaagcggcac gcaaccctcc gccgcggcgc ggcgtccctg actgcgacgg
    11941 cccgccgcgc ggagttcgac cgtcacggtg ggcgcacagg ggagggtgca cgatgagcga
    12001 cgagccgcgc tccgacatcc cggaaacctc cgggcgggac gccgtcgtga tcggcggcgg
    12061 gctcgccggc atcaccgccg cgctaacgct cgccgacgcg ggcgtgcgcg tcaccctgct
    12121 cgagagtcgg ccccggctcg gcggactggc cttctccttc cagcgcgacg gactcaccgt
    12181 cgacaacggc cagcatgtgt acctgcgctg ctgcaccgcc taccgctggt tcctcgaccg
    12241 catcgagggc acggcgctgg caccgatcca gaaccgcctc gacgtgcccg tcgtcgacct
    12301 cgccaagccc gagggacgac ggctcggcag actgcggcgc gacgcgctgc cggtccccct
    12361 ccacctgggg cgcagcctcg ccacgtatcc gcacctctcg ctcgccgacc gcgccagggt
    12421 cggccgggcc gcgctcgcgc tcaagggact cgatctcgcc gatccggccc tggacgcgca
    12481 ggacttcggc agctggctga ccgcgcacgg tcagtcggcg cgtgccgtcg aggccctgtg
    12541 ggacctggtc ggcgtcgcca ccctcaacgc ggtcgcgggc gacacctccc tggcactcgc
    12601 cgcgatggtg ttcaagaccg gcctgctgtc cgacccgggc gccgccgaca tcggctgggc
    12661 ccatgtcccg ctgggcgaac tgcacgaccg gctggcccgc aaggccctcg actccgcggg
    12721 cgtgcgcacc gagatccgta cccgtgtcac ctccgtctcc gccgaggaca acggcagttg
    12781 gaccgttcag gtgcccggcg agacgctccg cgcggacgcc gtcgtgctcg ccgtaccgca
    12841 gcgtgagacg tacgacctgc tgccggacgg ggcgctcgac gcccccgagc ggctgctgga
    12901 catcgggacg gcgccgatcc tgaacctgca cgtcgtctac gaccgcaagg tgctcgacgt
    12961 ccccttcctc accgcgctgg gcacccccgt gcagtgggtg ttcgaccgca ccgacgcctc
    13021 cgggctgtcg acaggccgcc ccgaagggcc tgacgagggc cgtggcgggc gacggtcggg
    13081 acagtacctc gccgtctcgc agtccgccgc gcacgaggac atcgacgcac ccgtcgccgc
    13141 cctgcgcgag cgctacctgc ccgaactgga gcggctgctg ccggccgccc gcggcgccac
    13201 ggtgcgggac ttcttcgtga cccgggagcg cacggccacc ttcgctccca cccccggcgt
    13261 cggacggctc aggcccggcg cccgcaccaa ggcatccggc ctgtacctgg ccggagcgtg
    13321 gaccgccaca gggtggcccg cgaccatgga gagtgcggtc cgcagcggcg tcagtgcggc
    13381 ggacgccgcc ctcggcgccc tcggccggcc ccgcccccgc cgcctcttcg ccgtcgagga
    13441 ggccgcctga tgaccgatca gcacggctcg gcacaccccc gcaccccctc cggtaacgcg
    13501 acaagaggag aaactgtgcc cactgtgccc ccggccgaga aggccgctcg gaggaccgcg
    13561 gtggacgtga ccgcgctgct ggagcgcggc cggaccctgg ccacaccggt gctgcgcgcg
    13621 gccgtcgacc gcctggtgtc tcccatggac acggtcgccg cctaccactt cggctggatc
    13681 gacgcccagg gcaacccgac cgacggggac ggcggcaagg ccgtacgtcc cgcgctcgcg
    13741 gtgctctccg cccaggtcac cggagccgcg cccgaggtgg gcgtgcccgg ggcggtcgcc
    13801 gtcgaactgg tccacaactt ctccctcctg cacgacgacc tgatggacgg cgacgagcag
    13861 cgccgtcacc gcgacaccgt ctggaaggtg cacggccccg cccaggccat cctggtcggc
    13921 gacgccctgt tcgccctcgc aggcgaggtc ctcctcgaac tcggcacggt cgaggcgggc
    13981 cgggccgccc ggcggctgac caccgcctcc cgcgccctga tcgacggcca ggcccaggac
    14041 atgtcctacg agcaccgcga ccgtgtcagc gtcgaggagt gcctggagat ggagggcaac
    14101 aagaccggcg ccctgctggc ctgcgccagc tcgatcggcg ccgtgctggg cggcgcggac
    14161 gcgcgcaccg ccgacaccct ggagcgttac ggccaccacc tcggcctggc cttccaggcc
    14221 gtcgacgacc tcctcggcat ctggggagac ccggaggcca ccggcaagca gacctggagc
    14281 gatctgcgtc agcgcaagaa gtccctgccg gtcgtggccg ccctcgccgc cggcggcccc
    14341 gcctccgagc agctcgggga gatgctcgcc gccgacgcca agcgccagga cttcgcgaac
    14401 ttctccgagg aggagttcgc ggcccgcgcc gcgctcatcg aggaggccgg cggccgcgag
    14461 tggaccgccg gggaggcacg ccgtcagcac accgtcgcca tcgaagccct gaacgccgtc
    14521 gacatgcccg agcaggtgcg ggaccagttc acggcgctcg ccgacttcgt cgtcgtacga
    14581 aagagatgat cactatcggt cgaataaccc tcgcgtagtc gccggccggt gtcgcgggaa
    14641 gagacgcacc ggccgacggc ggacccacag cagacgcaac gccatgcaca ctgcacgaag
    14701 gggaagccat gacagcgacg accgacggaa gcaccggggc cctcccgccc cgcgctgccg
    14761 cggccagcga aacccgtatc gacatccccg cggcggccgg ggtacaagaa gccgccgtgc
    14821 gcgcggtcca gcgcgcgacc gacttcctgc tcgcccggca ggacgtcgag ggctggtgga
    14881 agggcgacct cgagacgaac gtcaccatgg acgccgagga tctgctgctc cgtcagttcc
    14941 tggacatcca ggacgagtcg acgacccgtg ccgccgccct cttcatccgc ggcgaacagc
    15001 gcggggacgg aacctgggcc accttccacg gcggccccgg cgacctctcc gccaccatcg
    15061 aggcgtacgt cgccctgcgg ctggccgggg acgagcccca cgcgccgcac atggccaagg
    15121 cctccgcctg ggtccgcgac cagggcggga tcgccgccgc ccgggtcttc acccggatct
    15181 ggctggcgct gttcggctgg tggaagtggg aggacctgcc cgaacttccg ccggaactcc
    15241 tctacttccc gaagtggttc ccgctcagca tctacaactt cggctgctgg gcccggcaga
    15301 ccatcgtgcc gctcaccgtc gtctccgcga agcgcccggt gcgtccggcg cccttcccgc
    15361 tcgacgaact gcacaccgac ccggccgatc ccaacccgcc caggcccctg gcgccggtgg
    15421 ccagttggga cgggttgttc cagcggctgg acaaggtcgt gcgcggctac cgcaaggtcg
    15481 cggtgcgcag actgcgcaag gccgccctga actccgccgc ccgctggatc gtcgagcggc
    15541 aggagaacga cggctgctgg ggcggcatcc agccgccggc cgtgtactcg gtcatcgccc
    15601 tgtacctgct cggctacgac ctcgaacacc ccgtgatgcg agagggcctc aagtcgctgg
    15661 accggtacgc ggtgtggcgc gaggacgggg cccggatgat cgaggcctgc cagtcacccg
    15721 tgtgggacac ctgcctcgcc accatcgcgc tggccgacgc gggggtgccg gccgaccacc
    15781 ccaaactggt caaggcggcc gactggatgc tgggcgagca gatcgtgcgg cccggcgact
    15841 ggtccgtacg gcggcccggg ctcccgcccg gtggctgggc cttcgagttc cacaacgaca
    15901 actaccccga catcgacgac accgccgagg tggtcctcgc gctgcgccgg gtccgccacc
    15961 acgacccgga ccgggtggag agcgcgatcg ggcgcggggt gcgctggaac ctcggcatgc
    16021 agtccaggaa cggcgcctgg ggcgcgttcg acgtcgacaa caccagcccc tttcccaacc
    16081 gcctgccgtt ctgcgacttc ggcgaggtca tcgacccgcc gtccgcggac gtcaccgcgc
    16141 acgtcgtcga gatgctcgcg ttcgagggcc tctcccacga tccgcgcacc cggcgcggca
    16201 tcacctggct gctcgccgaa caggagccgg aaggctcgtg gttcgggcgc tggggcgtca
    16261 actacatcta cggcaccggc tcggtggtgc ccgcgctcac cgccgccgga ctgcccgccc
    16321 ggcacccggc gatccggcgg gcggtcggct ggctggagcg ggtacagaac gaggacggcg
    16381 gctggggcga ggacctgcgc tcttaccagg actcgacacg ctggagcggc cggggcgcct
    16441 ccaccgcctc ccagaccgcc tgggcgctga tggcgctgct ggcggccggg gagaaggact
    16501 ccaaggccgt cgagcggggc gtcgcctggc tcgccgagac ccagcgcgag gacggttcct
    16561 gggacgagcc gcagttcacc ggcaccggct tcccgtggga cttctccatc aactaccacc
    16621 tgtaccggca ggtgttcccg ctgaccgcgc tcggccggta cgtccacggc gagcccctcg
    16681 tcgtgaaggc accgtctccc gccgaggccg aaggacgctg atgaacgccc agcccgcctc
    16741 cgccccgctg ctgatcgcct gcgcgctcgg catcgagcac ctcgcgctgc gcatgggcga
    16801 ccgcggcggg gccggcgggc cggtgaccgt cctgcgcacc ggcatggggc cgaaggcggc
    16861 cgagcgctcc gtcacccggg tcctcgccga cccggtgctc ggcggggcgg ccgtgctcgc
    16921 caccggcttc tgcgcgggac tggcccccgg catgcacccc ggcgacctcg tcgtcgccga
    16981 ggagacccgc gacccgctcg gcaccgtgcc gtgcgtgaac accgacctgc tcgtcaagga
    17041 actcgtgcgc accctgcccg ggcgcaccgt ccacaccggc cccctgaccg gctccgacca
    17101 cgtggtgcgc ggcccggagc ggtccgacct gctcgccacc ggcgcgatcg cggtcgacat
    17161 ggagtcggcg gccacgctgc tgagcgccgt ccgcgcgggc acgcgcccgg ttgcggccgt
    17221 ccgggtggtc gtggacgctc ctgaacatga actcgtccgg atcggcacgg tacgcggtgg
    17281 aatatcggcg ttccgcgtcc ttcgttccgt cctgcctgca ttcttcgaat ggcaccgcaa
    17341 tgtgctgctc ccccggaggt gagccagatg gccatgccgc tgcgccagtc catcaaggtc
    17401 gctacgtact tggctgaaca gaagctccgc aagcgggaaa agtttccgct catcgtcgag
    17461 ctggaacccc tcttcgcctg caacctggcg tgcgagggct gcggcaagat ccagcacccg
    17521 gccggtgtgc tgaagcagcg catgccggtc gcccaggccg tgggcgcggt actcgagtcc
    17581 ggtgcgccga tggtctccat cgccggcggc gagccgctga tgcatcctca gatccacgag
    17641 atcgtacggc agttggtggc gaggaagaag tacgtcttcc tctgcaccaa cgccatgctg
    17701 atgcgcaaga agatggacag gttcacgccc tcgccctact tcgccttcgc ggtgcacatc
    17761 gacggtctgc gcgagcggca cgacgagtcc gtcgccaagg agggcgtgtt cgacgaggcg
    17821 gtggaggcga tcaaggaggc caagcggcgc ggcttccggg tcaccaccaa ctcgaccttc
    17881 ttcaacaccg acaccccgca gaccatcatc gaggtgctca acttcctcaa cgacgacctc
    17941 aaggtcgacg agatgatgat ctcgcccgcc tacgcctacg agaaggctcc cgaccaggag
    18001 cacttcctcg gcgtggagca gacccgggag ctgttcaaga aggccttctc cggcggcaac
    18061 aggcgccgct ggcggctcaa ccactcgccg ctcttcctgg acttcctgga gggcaaggtc
    18121 gatttcccgt gcacggcctg ggcgatcccg aactactccc tcttcggctg gcagcggccc
    18181 tgctacctga tgagcgacgg ctatgtgccg acgtaccggg aactgatcga ggagaccgac
    18241 tgggacaagt acggccgcgg caaggaccca cgctgcgcga actgcatggc gcactgcggc
    18301 tacgagccca ccgccgtcct cgccaccatg ggctcgctca aggagtcgct gcgggccatg
    18361 cgcgagaccg tctccggaaa ccgcgactag cgctgtgacc gccatctcct tgggcattcc
    18421 cgaggtaccg gtccggccga tcgccgcgcg gcgcgtgtcg cggcggatcc aggtcggacc
    18481 ggtggcggtc gggggcgggg ctccggtgtc ggtgcagtcg atgacgacga cccggacgtc
    18541 cgacatcggc gcgacgctcc agcagatcgc cgagctgacg gcgtccggct gccagatcgt
    18601 gcgcgtcgcc tgcccgaccc aggacgacgc cgacgccctc gccaccatcg cccgcaagtc
    18661 ccagatcccg gtgatcgcgg acatccactt ccagccgaag tacgtgttcg ccgcgatcga
    18721 ggccggctgt gccgctgtcc gcgtcaaccc gggcaacatc aagcagttcg acgacaaggt
    18781 caaggagatc gcgaaggccg cgaacgagca cggcaccccg atccgcatcg gcgtcaacgc
    18841 cggctccctc gaccgccgcc tgctccagaa gtacggcaag gcgacccccg aggccctcgt
    18901 cgagtccgcc ctgtgggagg cgtccctctt cgaggagcac gacttccgcg acatcaagat
    18961 ctccgtcaag cacaacgacc cggtcgtgat ggtcgaggcc taccggcaac tggccgccca
    19021 gtgcgactac ccgctgcacc tcggggtgac cgaggcgggt ccggcgttcc aggggacgat
    19081 caagtcggcc gtggccttcg gggcgctgct ctcgcagggg atcggggaca cgatccgggt
    19141 gtcgctgagc gcgccgcccg cggaggaggt caaggtcggc atccagatcc tggagtcgct
    19201 gaacctcagg cagcgtgggc tggagatcgt ctcctgcccg tcctgcggcc gcgcccaggt
    19261 cgacgtctac aagctggccg aggaggtcac cgcggggctg gagggcatgg aggtcccgct
    19321 ccgggtcgcg gtcatgggat gtgtggtcaa cggccccggc gaggcgcggg aggcggacct
    19381 gggagtcgcc tccggcaacg gcaaggggca gatcttcgtc aagggcgagg tcgtcaagac
    19441 cgtgcccgag tcgaggatcg tggagaccct catcgaggag gcgatgaaga tcgcccagcg
    19501 gatggaacag gacggcgtcg cctccggagg gccggccgtc accgtgagtt gaacagcacg
    19561 gaccgagagg gggcccgagc gtgacgattc tggagaacat tcggcagccg cgcgacctga
    19621 aggcgctgtc cgaggtggaa ctcggcgaac tgtgctgcga gatcagggag ttcctggtgc
    19681 acgccgtcgc caggaccggc ggacacctcg ggcccaatct gggcgtggtg gaactgaccg
    19741 tcgccctgca ccgggccttc gagtcgccgg tcgaccgcat cctgtgggac accggccatc
    19801 agagttatgt gcacaagctt ctgacaggac gtcaggactt ctccaagctg cggggcaagg
    19861 gcggcctgtc cggctacccc tcgcgcgagg agtccgagca cgacgtcatc gagaacagcc
    19921 acgcctccac cgccctcggc tgggccgacg gcctcgccaa ggcccgccag gtgcggggcg
    19981 agaagggcca cgtcgtcgcg gtcgtcggcg acggcgcgct caccggcggc atggcctggg
    20041 aggcgctcaa caacatcgcg gccgccaagg accggccgct gatcatcgtc gtcaacgaca
    20101 acgaacgctc ctacgccccg accatcggcg gcctcgccga ccacctggcc accctgcgca
    20161 ccaccgacgg ctacgagaag gtgctggcct gggggaagga cgtactgctg cgcacgcccg
    20221 tcgtcggcca caccgtctac gagtcgctgc acggcgcgaa gaagggcttc aaggacgcct
    20281 tcgcgccgca ggggatgttc gaggacctgg gcctgaagta cgtcggtccc gtcgacgggc
    20341 acgacatcgg ggccgtcgag tcggcgctgc ggcgggccaa gcgcttccac gggccggtgc
    20401 tggtgcactg cctgaccgag aagggccgcg gctacgagcc cgctctcgcg cacgaggagg
    20461 accacttcca caccgtcggg gtgatggacc cgctgacctg cgcaccgctc gccccggccg
    20521 gcgccccctc ctggacgtcc gtgttcggcg acgagatcgt gcggatcggc gaggaacgcg
    20581 acgacgtcgt ggcgatcacc gccgccatgc tgcacccggt cggcctcggt gagttcgccg
    20641 cccgcttccc cggccgggtg tgggacgtcg ggatcgccga acagcacgcg gcggtgtccg
    20701 cggccgggct ggccaccggg ggcctgcacc ccgtcgtcgc cgtgtacgcc accttcctca
    20761 accgggcctt cgaccagttg ctgatggacg tggccctgca ccgctgtggg gtcacgttcg
    20821 tcctcgaccg cgccggggtg accggggtgg acggcgcctc ccacaacggc atgtgggaca
    20881 tgtccgtcct ccaggtcgtc cccggcctca ggatcgcggc cccgcgcgac gccgaccaac
    20941 tgcgcgcgca actgcgggag gcggttgccg tggacgacgc gcccaccctg atccgcttcc
    21001 cgaaggagtc ggtcggaccg cggatcccgg ccgtcggcca cgtcggcggc atggacgtac
    21061 tgcaccgcgg cgcggcgccg gaggtcctcc tggtcgccgt cggcgtcatg gcaccggcct
    21121 gcctcagggc cgccgaactg ctggaggccc ggggcatcga ctgcacggtg gtggacccgc
    21181 gctgggtgaa acccgtcgac ccggccctgc ccggcctcgc cgccgagcac cgtctggtgg
    21241 ccgtcgtcga ggacaacagc cgtgcggcgg gcgtcggttc ggccgtcgct ctggccctcg
    21301 gagacgccga ggtcgacgtg cccgtacggc ggttcggcat cccggagcag ttcctcgccc
    21361 acgccaagcg ggccgaggtg ctcgccgaca tcggcctcac gcccgtcgag atcgccggac
    21421 ggatcagcgc gagcctggcc gtccgcgacg ccggcggccc cgtcaaggag acaacgcaat
    21481 gagcacggag ttcgacctcg gcgcgctgct ggccgagcgc ggagccgaac gctacgagct
    21541 gcacgccaga tacctcaacc accaactgcc gcgcatgctg cacaccatcg gcttcgacaa
    21601 ggtctacgag cggggcgagg gcgcgtactt ctgggacgcg gacggcaacg actacctgga
    21661 catgctcgcc gggttcgggg tgatgggcct gggccgccac caccccgtcg tccgcaaggc
    21721 gctgcacgac gtcctcgacg catcgctcgc cgacctcacg cgcttcgact gccagccgct
    21781 gcccggactg ctggccgaga agctgctcgc ccacagtccg cacctggacc gggtgttctt
    21841 cggcaacagc ggcacggagg ccgtggagac cgccctgaag ttcgcccggt acgccaccgg
    21901 gaagccgagg gtcctgtact gcgaccacgc cttccacggg ctcaccacgg ggtccctgtc
    21961 ggtcaacggc gagggcgggt tccgcgacgg cttcgcgccg ctgctgcccg acaccgccgt
    22021 acccctcggc gatctcgacg cgctggcacg ggagttgcgg aagggcgacg tggccgcgct
    22081 gatcgtcgag ccgatccagg gcaagggggt gcacgaggcc ccgcccggtt atctgcgtgc
    22141 cgcccaggag ctgctgcacc ggcacagggc gctgctcatc gccgacgagg tgcagaccgg
    22201 cctcggccgg accggcgact tctacgccta ccagcacgag gacggcgtcg aaccggacct
    22261 ggtgtgcgtc gccaaggccc tctccggcgg ctatgtgccg gtcggcgcca cgctcgggaa
    22321 ggactggatc ttcaagaagg tctactcgtc catggaccgg gtgctggtcc actcggcgag
    22381 cttcgggtcc aacgcacagg ccatggcggc cgggctcgcc gtgctgtccg tcatggagaa
    22441 cgagcagatc gtcgcgggcg cccgcctgac cggcgacctg ctgaagtccc ggctcacggc
    22501 gctgatcgac aagtacgagc tgctcgccga cgtccgtggc cggggcctga tgatcggcat
    22561 cgagttcgga aagccccgat ccctgaaact gcgcagtcgc tgggccatgc tccaggcggc
    22621 gcgcaagggg ctgttcgcgc agatggtggt cgtcccgctg ctccagcggc accgcatcct
    22681 cacccaggtc tccggcgacc acctggaggt gatcaagctg atcccgccgc tggtggtggg
    22741 cgagccggag gtgaaccggt tcgtggacgc cttcaccgag gtgatggacg acgcgcacaa
    22801 cgggggcggt ctggtctggg acttcggcag gacactgatc aagcaggcgg tggccaaccg
    22861 gtaggtcctc ccgcccctgc cgacgccttt ttgcctctga ggcaacaagt ttgccccaga
    22921 ggcaaagttc cggctgaatg gaggcatgag ccaccccgcc tccgagcccg ggcccgaacc
    22981 ggcggacgac ctgggcgtcg tcgcgcccca gctccgcgcc ctgcgccggc gcgcctccct
    23041 caccctggag gccgcggccc gcgccgccgg gctgtcaccg gcccacctct cccgcctgga
    23101 gaccgggcag cgccagccct cgctgcccat gctgctcgca ctcgcccgcg tctacggtac
    23161 gaccgtctcc gaactcctcg gtgagagggt cgccgaccgg gacgccgtcg tacgcgccgc
    23221 cgacatggag cccacccacg ccggcggctg gacctactgg cagtccggcg cctccgggcg
    23281 gggcatgcag gcgctgcgcg tgcaggtgcc gtacggctcg cagggcgaca tcgtgcgggt
    23341 gcatccgggc gaggagtggc tgcacgtcct gcggggacgg ctgcggctgc gcctcgggga
    23401 caccacgcac ctgctcggcg cgggggacag cgcgcacttc gactcgctga ccccgcaccg
    23461 catcgccgca caggaccccg acggggtcga cctgctgttc gtccacaccc tgttgcagag
    23521 cccgacggcc gcgctgtgcc tcggccccac ccctggagag acgccatgac cgacatcgag
    23581 gagaagttcc ccaggagcct gtggatccgg ctgatcatct acatcgcggt ggggcatgtc
    23641 ttcgccgggt tcctgtggct gctgttcgag gtcggcgcca agcggtagcc gacggccctc
    23701 ggccggcggg gtgctcagtc gagcaggcgc tcgcggagcc gctcgcgggt ccgaggcgtc
    23761 aggccgaggc cctgctccag gtaggtgtcg acaccgcccc aggtctcctc gacggtctcg
    23821 aacgcggccg tcaggtactc ggcacgggcg tcgaagaggg ggtcgagcag ctccatgacc
    23881 tcgggggagt acgccgcggc ggaggtgccg ctgcggcgca ccttgtagcg gcggtgcttg
    23941 gcgctggact ccaggtagtc ggccaggatc gcgtcgcgct ccacacccag ggcgagcagg
    24001 gtcacggcga tggacaggcc ggcgcggtcc ttgcccgccg cgcagtgcat cagcgccggg
    24061 acgctgtcct ccgcgaggga gtgcaggacg cgggagtgct cgcccgtgcg ctccttcatg
    24121 atcgagcggt aggaggcgat catccggccg gccgccctgc cgtcgccgag gatctcgcgc
    24181 agctgctcga tgtcgccttc gcggaccatc ttccagaact cggcgccgtc cgcagggtcg
    24241 gagagcggca ggttcacatt gcgcacgccc ggcagctcga cgtcggggcc ctccagcttc
    24301 tggtccgccg cgttgcggaa gtcgaagacc gtgtgcaatc ccagcgagga gaggaacgcg
    24361 acgtcctcgt cggtggcgtg cgcgaggtgg ccgctgcgga acagcacgcc gtggcggacg
    24421 cgccggccgt cgacggtcgg caggccgccc acgtcccgga agttgcgcac tccggccagc
    24481 tcgggctcgg tcgacgggat ctgctgcgtc acgggggctc ctcccggtct tcggtcccgg
    24541 ccggcgcggc tcgagatggc caccggaaca cctcattgac catacgacat ggatgcccgg
    24601 ggcaaacggg ttgtccacag ggggctccgg tggttgtgcg gcgcctggcg cgtacgtcgg
    24661 accggggcgg gcgggggaga gggcggctcg gggtgtccgg ctggggcggg gtgcggtgaa
    24721 cgagggttgc cggggaaggg gtggtgggcg gggtggcggg gcgcctgatc ggggtcacct
    24781 gggctgagcg aggccctcgg ccggtggctc gaggggcggc acccgggcga gtgatgcccc
    24841 ttgcgggcgg gggagtgctg gctgtggggc ccggccaggg tggcgggtgg ccggggtggc
    24901 ggtccgcgtg tgagggggcg ggggcccgtg gcgagaggag ccgcccgggc ggcggtgccg
    24961 gatcctggtg ggatcagtcg ggcgatgacc tcgcccgact gtggtgcccg agtggcggcc
    25021 ttcgagaggg agttgcccga gcggggctcg gccaggtcgg agggtcgccc gggcgatgac
    25081 ggccggtgac agtaggcttc ccgggccccc ggccgggtgc ggttccagcc cggatgaaag
    25141 cggacggaac tgtgcaatca actcgtactg caccccgcgc gccaggacgt ccaggagcgc
    25201 cggggctcga tccggcaacg gtgtgcgaat gccgcgaaac gggcgaagtt gaccgaggcg
    25261 cgatactgct gcgccactgg ttgcgcaccg ggccgcaagg tggccttgat gcgtcggtta
    25321 tccggcagcg tcgcatctgg gagttctgtc cgaattggat ccttcgtaat aactcgctct
    25381 ggaataaggg gctctgggga catgtcacgt gagcagcgtc atattcgtga ctatgagtcg
    25441 cccgtcatgt gcacgtaata cggctgtttc tcaagggtgt ttgtgggaag agcggcctct
    25501 cgatacacgc agggtgaccg ggaattctca caggggatca agagaagcgc gcggtgagtg
    25561 caaccttcgc ttgtacctgt gcgtcgtggt cgcttacgtt ccacccaatc cggacggacg
    25621 cccaatcctg ccgccgcccg gagaccgcac actcacccgt gaacggcagg agcgggggac
    25681 ccacaggcag taccgcctgt tccggtctcc ggaacggcta ggggtaaagc cgcgcctcgg
    25741 cgcggccgga catctccagt ccgcacccga cagctcacct cgcaggcgcc ggagaggaat
    25801 tcgtcatgcc cgccaagggt aagcaccgtc gtccgaagtc ccagcgcttc acccgttcca
    25861 tcgccgtcgc cggaaccggt ggcgccgcgc tcgccctccc gttgatgggg gccaccggcg
    25921 cgcaggccgc accgtcccag tcggcgacgc agtcggtttc cgccgcctcc gccgtttcct
    25981 cccttccctc ccattcctct gtttcggaaa aggccgccga gaccgtttcc gtgacgcaga
    26041 agtccgggaa gtccgccacg ggcgccaaga cctacacggt gcagtcgggc gactacctct
    26101 ccaagatcgc ggacgagcag aacgtcagtg gcggctggag ccggctctac gcggacaacc
    26161 gtgaggccgt cggcgaggac ccgtcgctga tccacccggg actgaagctc tcgatcggcg
    26221 agaaggccgc gaccggcacg accaagtcgc cgtccacgtc gtccggttca tctacgtcgt
    26281 ccgggtcgtc gacctcgccg aagcagtcct cgggctcctc cgcgaagtcg tcctcctcgg
    26341 actcgggctc ttcggactcc gcgaagtcct cctcgtcgaa ggcgtccacg gcgcaggtcg
    26401 ccgagaaggc caccacctcc agtggcttcg ccctcccggt ggcgggtgcg accgtcggca
    26461 ccccgtacaa gatgtccggc agcatgtggt ccagcggtta ccacaccggc gtcgacttcg
    26521 tcgtcccgac cggcacctcg ctcaaggccg tcggcgcggg cacggtcgtc tccgcgggct
    26581 ggggcggcgc gtacggcaac caggtcgtca tcaagctcgc cgacggctac tacgcccagt
    26641 acgcccacct gtcctcgctc tccgtctcgg ccggccagtc cgtctccggc gggcagcaga
    26701 tcggcctgtc cggtgcgacc g
//
