LOCUS       NZ_CP099468            23668 bp    DNA     linear   CON 04-JUL-2024
DEFINITION  Streptomyces phaeoluteigriseus strain Qhu-M197 chromosome, complete
            genome.
ACCESSION   NZ_CP099468
VERSION     NZ_CP099468.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces phaeoluteigriseus
  ORGANISM  Streptomyces phaeoluteigriseus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1  (bases 1 to 9026270)
  AUTHORS   Zhang,B., Xiang,X. and Fan,J.
  TITLE     Complete genome sequence of soil microorganisms Streptomyces sp.
            Qhu-M197 isolated from Alpine meadows habitats on the Tibetan
            Plateau
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9026270)
  AUTHORS   Zhang,B., Xiang,X. and Fan,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2022) Faculty of Eco-Environmental Engineering,
            qinghaiuniversity, No. 251 Ningda Road, Chengbei District, Xining
            City, Qinghai Province 810000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Hifiasm v. v0.14; Circlator v. v1.5.5; Pilon v.
            v1.22
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 68.51291x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023923245.1-RS_2024_07_04
            Annotation Date                   :: 07/04/2024 06:06:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,100
            CDSs (total)                      :: 8,006
            Genes (coding)                    :: 7,707
            CDSs (with protein)               :: 7,707
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 299
            CDSs (without protein)            :: 299
            Pseudo Genes (ambiguous residues) :: 0 of 299
            Pseudo Genes (frameshifted)       :: 130 of 299
            Pseudo Genes (incomplete)         :: 241 of 299
            Pseudo Genes (internal stop)      :: 34 of 299
            Pseudo Genes (multiple problems)  :: 90 of 299
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:40:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2609299
            Orig. end                         :: 2632967
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP099468.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23668
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="indole"
                     /product="hydrogen-cyanide"
                     /region_number="7"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..23668
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="neighbouring"
                     /product="indole"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..21167
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21167
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11167](+)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11167
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     misc_feature    complement(115..126)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    complement(177..192)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.45"
                     /tool="antismash"
     misc_feature    541..555
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     misc_feature    complement(890..908)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.56"
                     /tool="antismash"
     misc_feature    893..911
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 23.37"
                     /tool="antismash"
     misc_feature    complement(897..915)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.09"
                     /tool="antismash"
     misc_feature    complement(910..928)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 23.03"
                     /tool="antismash"
     misc_feature    919..934
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.2"
                     /tool="antismash"
     gene            1024..2154
                     /gene="sucC"
                     /locus_tag="NFX46_RS11620"
                     /old_locus_tag="NFX46_11620"
     CDS             1024..2154
                     /EC_number="6.2.1.5"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sucC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994200.1"
                     /locus_tag="NFX46_RS11620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11620"
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="WP_252556342.1"
                     /transl_table=11
                     /translation="MDLYEHQARELFEEHGIAVPRAEVTDSSKEAREIARRLGGRALVK
                     AQVKTGGRGKAGGVKLAADPASAELTARHILGMDIKGHTVATVMLAQPVDIESEFYVSY
                     VLDRAAGRFLAIASAEGGMEIEEVAARRPDAVARVHIDPARGVTSAKAGEIVAAAGLPA
                     QAVDVLVRLWQVLVREDALLVEVNPLVRTRQGRLVALDGKVTLDDNASFRQSRRGGAAA
                     EYGDPLEEEAAAKGLNYVKLDGEVGIIGNGAGLVMATLDVVAGCGARPANFLDIGGGAS
                     AGVMADGLAVILSDPAVKSVFVNVFGGITACDAVAEGIVRGLDTVRLTKPLVVRLDGNN
                     AARGRAILDEHRHPLVEQATTMDGAARRAARLATAA"
     gene            2164..3048
                     /gene="sucD"
                     /locus_tag="NFX46_RS11625"
                     /old_locus_tag="NFX46_11625"
     CDS             2164..3048
                     /EC_number="6.2.1.5"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sucD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019065002.1"
                     /locus_tag="NFX46_RS11625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11625"
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="WP_252548476.1"
                     /transl_table=11
                     /translation="MAVYLTKDSKVLVQGMTGGEGMKHTRRMIAAGTDVVGGVNPRKAG
                     RTVDFGDRAVPVFGSVADGIRSTGADVTVVFVPPAFAKSAVTEAADAGIGLAVVITEGI
                     PVHDSVAFTTYARARGTRLIGPNCPGLISPGQSNAGIIPADITKPGRVGLVSKSGTLTY
                     QLMYELRDVGFSTCVGIGGDPVVGTSHIDCLAAFEDDPDTDLVVLIGEIGGDAEERAAA
                     YVRDHVTKPVVGYIAGFTAPEGRTMGHAGAIVSGSSGTAQAKKEALEAAGVRVGSTPTG
                     TAQLVLDLLGNRT"
     gene            3168..4709
                     /locus_tag="NFX46_RS11630"
                     /old_locus_tag="NFX46_11630"
     CDS             3168..4709
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004980893.1"
                     /locus_tag="NFX46_RS11630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11630"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_252548479.1"
                     /sec_met_domain="Aldedh (E-value: 2.3e-98, bitscore: 328.6,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASTLTLKSGTSWADAWRRCLTAAPEAFREDRVLNLWNGAWQADG
                     RTLPATSPVDGSPVTGPPRLDRDTAHQAVRASLDQHRAWRHLPLTERRARVAATLDALA
                     AHRELLALLLVWEIGKPWRLAQADVDRAVDGVRWYVDGIEPMLAGRAPLDGPVSNIASW
                     NYPMSVLVHAVLVQALAGNAVIAKTPTDGGVACLTLACALAAREGIPVTLVSGSGGELS
                     DALVRAPEIGCVSFVGGRDTGAAVATAVTDLGKRHILEQEGLNTWGIWNHSDWDTLAAL
                     VPKLFDYGKQRCTAYPRFVVQRELFDAFLAAYLPAVRTLTVGHPLAVEKRDDPYPRLDF
                     GPVINAAKAKELHDQVAEAVDRGAVPLYRGDLADARFLPGQDTSAYVRPVTLLNPPPSS
                     PLHHAEPFGPVDTIVLVDTEAELLAAMNASNGALVATLSTDDRATYERLAPQIRAFKVG
                     HGTPRSRGDRDELFGGFGASWRGAFVGGELLVRAVTRGPTDERLPGNFPDYQLMP"
     gene            4785..5273
                     /locus_tag="NFX46_RS11635"
                     /old_locus_tag="NFX46_11635"
     CDS             4785..5273
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073062.1"
                     /locus_tag="NFX46_RS11635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11635"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_252548481.1"
                     /transl_table=11
                     /translation="MVRDRDPHPPPLELRHPGPLLGRAQSRLTGITTETLVSHGVDGRE
                     PAGLAVPADGAELSQADATARPGVDRTTMVSLTDGPEDHGLVERRPSPYDRRRNVVALT
                     APGEECLLQAERARRAAEHRFLAPPSEEAATALLPALRTPAAEEDPATGRPSLSAHAG"
     tRNA            5407..5491
                     /anticodon=(pos:2614739..2614741,aa:Leu,seq:gag)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="NFX46_RS11640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="NFX46_11640"
                     /product="tRNA-Leu"
     gene            5407..5491
                     /locus_tag="NFX46_RS11640"
                     /old_locus_tag="NFX46_11640"
     misc_feature    5592..5608
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.49"
                     /tool="antismash"
     misc_feature    5596..5605
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.4"
                     /tool="antismash"
     gene            5932..7104
                     /locus_tag="NFX46_RS11645"
                     /old_locus_tag="NFX46_11645"
     CDS             5932..7104
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971679.1"
                     /locus_tag="NFX46_RS11645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11645"
                     /product="ATP-binding protein"
                     /protein_id="WP_252548484.1"
                     /transl_table=11
                     /translation="MTDYIQNPVLWALLIAVLAAVALIVRQRRAARTLRQEFADLRARH
                     DELENGYAKSVEAAQERADEATKTVLKSAMRTLQGLAAEQQLIVSRLQKKYGESVILQD
                     LLEIDHTNSQFGRRAQSIAVLCDGWLGRQRDVASVYDVVRSAQGRIRHYRRVEILSQVD
                     FGITSRAVEPVALALAEMLDNATSYSSPDTVVEINIRTVPKGICIVVDDAGVGMNDEER
                     ARAEKLLSSDRVSGVSRLGNPPQFGFAVIGVLAERFGFEVSVDSTSPYGGVRAVLLLPH
                     DLLTNAPEQKEPTPAAPAVAAPTRGGPEPGPAPSTTVDGLPKRRRKRPMAIVPGSAPTA
                     AAPSRSGAETAAIMGAFQRGTQSGRRATPADPAEQSSSTRGASSEGHEFS"
     misc_feature    5937..5955
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.58"
                     /tool="antismash"
     misc_feature    6031..6033
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7101..7502
                     /locus_tag="NFX46_RS11650"
                     /old_locus_tag="NFX46_11650"
     CDS             7101..7502
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971678.1"
                     /locus_tag="NFX46_RS11650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11650"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_073497663.1"
                     /transl_table=11
                     /translation="MNDDLSWMLDSALEIPGALHAVLISADGLLMARTQDIGKDDADRV
                     AAAMSGVQSLSRSLAFFCEDAQQRWRQTLVEFDGGWVFLISAGEGAYLGVSASPDVDMA
                     DITFRMQQLVGQLGKALTTPPRENLGVRS"
     gene            7499..7876
                     /locus_tag="NFX46_RS11655"
                     /old_locus_tag="NFX46_11655"
     CDS             7499..7876
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971677.1"
                     /locus_tag="NFX46_RS11655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11655"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_073497661.1"
                     /transl_table=11
                     /translation="MTGFDELEPQTPELVRPYVITKGRGLPDEEQLSLITLVTAVADRQ
                     QRPTRLSPEEQSLLELCSAGYLSVAEIAGHTQLPLGVVKILLAALTEGGYLITRPPVQR
                     APVADREILEEVLNGLRAKFG"
     misc_feature    7538..7540
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7851..8444
                     /locus_tag="NFX46_RS11660"
                     /old_locus_tag="NFX46_11660"
     CDS             7851..8444
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358089.1"
                     /locus_tag="NFX46_RS11660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11660"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_073497659.1"
                     /transl_table=11
                     /translation="MVSGPSLDEQAYVREGASQTAVKILVVGHFAVGKTTFIGAISEIP
                     PLSTEETMTRAAEAVDDLKGVQGKTTTTVAMDFGRLTISDRVVLYLFGTPGQQRFVQMW
                     EDMARGALGALVLVDPERLADSFAVIDLIEQYGLDYAIAVNHFDGSPLRDETALRDALD
                     LLDDTPVVTCDARDEQSSAEALITLVRHLQDRAH"
     gene            8453..9793
                     /locus_tag="NFX46_RS11665"
                     /old_locus_tag="NFX46_11665"
     CDS             8453..9793
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125674.1"
                     /locus_tag="NFX46_RS11665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11665"
                     /product="cytochrome P450"
                     /protein_id="WP_252548486.1"
                     /transl_table=11
                     /translation="MDQPTAPVPPPGCPAHNSGARVPLHGPEFAADPQAYYSYLRHYGP
                     TAPVELAPGVEATLVTDYATALQLLQDSGSFRKDARRWRHFNEGKISPDSPVAPVLAYR
                     PNCMFSDGAEHLRLRQAVTDSMARIDTRKLSHSTEQVSNYLISQFASRGSADLLGDYAK
                     QLPLFVFNELFGCPPDIGDRVVYGITGMFDGINPARAMEVLFGAVGELVALKRVKPGED
                     VTSWLMEHQAALTDEEMVHQLALLLVGGNEPLRNLIGNTLHRLLTHDAYANQGGLIDEA
                     IDDTLWENPPMQNLAPHYPAADMEFAGQQLQAGDLLLVSFAAANTGPALTAARQAGSNR
                     AHLAWSAGPHACPSKDPARQITVTALENLLNKLPDVELAVPEESLTWRPGPFNRGLIAL
                     PARFTAVTERKPAPEARTEAARPEQPQPGTRAERSGVWSQFLNWLTR"
     misc_feature    9816..9831
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.79"
                     /tool="antismash"
     misc_feature    9898..9912
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.1"
                     /tool="antismash"
     gene            10001..11167
                     /locus_tag="NFX46_RS11670"
                     /old_locus_tag="NFX46_11670"
     CDS             10001..11167
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388029.1"
                     /locus_tag="NFX46_RS11670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11670"
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_252548488.1"
                     /sec_met_domain="indole_PTase (E-value: 2.3e-133, bitscore:
                     443.4, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGEPVTAARPGGPRRSGTETLGGHTSRQLRNLCEIVGLTAHDGE
                     VYARTLTEMLGAAAERPLDLPPPNPTFLSDDHTPVEFSLSFVPGAAPTLRVLLEPGCAA
                     GGLARNGRLGLRAVRETTARWGFATDRLDELEDLFLPPSPEGPLALWCALELRPGGVPK
                     VKVYLNPAAGGQKRAAATVGEALRRLGHRDAFAALPPHDRHLFFALDLGDWAEPRVKVY
                     LAHQDLSAAEAGALSRMEGGPLAAESEEFFRIASGQDGDEEGGGTASAPVVRRPVQSCH
                     AFTETASGLPSGFTLYVPVRDYARHDGDALTRATALLGRYGQDPAPLLGAVSAVTDRSP
                     EDGVGLVAYLALAHQQGQPPRVTAYVSSEAYEVRPPAGLLPAEPATVR"
     cand_cluster    10732..23668
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    10732..23668
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[15731:18668](-)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(15732..18668)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="2"
     gene            complement(11356..12642)
                     /locus_tag="NFX46_RS11675"
                     /old_locus_tag="NFX46_11675"
     CDS             complement(11356..12642)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FMO-like"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014136892.1"
                     /locus_tag="NFX46_RS11675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11675"
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_252548491.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.3e-10, bitscore:
                     37.9, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FMO-like (E-value: 6.9e-76, bitscore:
                     254.6, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVCVIGAGLSGLAAARALETAGVDFVCLERSGDVGGIWRRPEAG
                     ERGPGYLSLHLNTTKGLTGYADYPMPASYPVYPRHSQVASYLRAFAEWADVLDHIELGT
                     SVESVRQEADGSWTVVAVDAGGTRGARSFSHVVVASGHNTEPSLPAPPPGSDTFTGTIL
                     HALDYRDGSDYAGQRVVVVGLGASAVDIAADLSRYAATTLLSVRRGLHILPKQLFGIPL
                     DEVAEAPWWTSMSLAEQRRFIEQALLVARGRLSDYGLPEPDHPVFASAVTISDEILTRI
                     RHGGVVPKPAIASLDRDRVVFTDGSSARADAIVHCTGYRMAFPFLPSGCPIGERGSVEL
                     YKRVVAPGHAGLYFVGLVRPHGSITRLVEAQSRWIARIVSGAAVLPEPEVMRKEVAIYL
                     SGIAGQYGQAEGASIQVNVAPYLQELQDV"
     gene            complement(12768..13466)
                     /locus_tag="NFX46_RS11680"
                     /old_locus_tag="NFX46_11680"
     CDS             complement(12768..13466)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069837.1"
                     /locus_tag="NFX46_RS11680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11680"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_094102520.1"
                     /transl_table=11
                     /translation="MAAPRSISPSPAAPALPVLGGRRSSYRERVADALRAALIAGELRP
                     GQVYSAPTLAARFGVSATPVREAMLDLAKEGLVDAVPNKGFRVTDVSDRQLDEYTHVRA
                     LIEIPTVVALATTADPVSLEALRPAAREIVTAAVAGDLIAYVEADTRFHLGLLALAGNS
                     HLVEVVRDLRGRARLYGLTALSASGRLLASAEEHLELLDALLARDERAVRTVMTRHLGH
                     VRGLWASADA"
     misc_feature    13515..13525
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: strong, score: 22.05"
                     /tool="antismash"
     gene            complement(13711..14712)
                     /locus_tag="NFX46_RS11685"
                     /old_locus_tag="NFX46_11685"
     CDS             complement(13711..14712)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358096.1"
                     /locus_tag="NFX46_RS11685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11685"
                     /product="proline racemase family protein"
                     /protein_id="WP_252548493.1"
                     /transl_table=11
                     /translation="MRSKLVLHAVDSHTEGMPTRVITGGIGTIPGATMNERRLYLREHR
                     DEVRQLLMNEPRGHSAMSGAVLQPPTRADCDWGVVYIEVSGYLPMCGHGTIGVATVLVE
                     TGMVEVVEPVTTIRLDTPAGLVVAEVAVRDGAATAVTLHNVPSFAVALDREITLPDGRT
                     VTYDLAYGGNFYAILPLEEFGLPFDRSRKDDILRAGLSLMEAINAEGEPVHPQDPSIHG
                     CHHVHLYAPGATARHSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGELPLHTEFVNES
                     FIGTRFTGRLLGRTEVAGVPAVLPSFTGRAWVTGTAQYLLDPTDPFPAGFTL"
     gene            complement(14737..15627)
                     /locus_tag="NFX46_RS11690"
                     /old_locus_tag="NFX46_11690"
     CDS             complement(14737..15627)
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525029.1"
                     /locus_tag="NFX46_RS11690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11690"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_252548495.1"
                     /transl_table=11
                     /translation="MTTPRPWHGVLVATALPLRDDLSVDLDRYAEHCAWLVANGCDGVV
                     PNGSLGEYQVLTPEERAAVVRTAVAAIGGERVMPGVAAYGSAEARRWAEQAREAGCGAV
                     MLLPPNAYRADEGAVVAHYTEVAQAGLPVVAYNNPIDTKVDLVPELLARLHGEGLIHGV
                     KEFSGDVRRAYRIAELAPELDLLIGADDVLLELAVAGAKGWVAGYPNALPRASVNLYRA
                     AVAGDLTTALPLYRQLHPLLRWDSRVEFVQAIKVSMDVVGRYGGPCRPPRVPLPPEQEA
                     AVRAATEKAVAAGLA"
     misc_feature    complement(15661..15671)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 19.65"
                     /tool="antismash"
     gene            complement(15732..17171)
                     /locus_tag="NFX46_RS11695"
                     /old_locus_tag="NFX46_11695"
     CDS             complement(15732..17171)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676293.1"
                     /locus_tag="NFX46_RS11695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11695"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_252548498.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.2e-26, bitscore:
                     89.9, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 1.6e-11, bitscore:
                     43.3, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTERRQVLAVIGAGPAGLAAALAAAARGVRVVLVDSAAEPGGQFY
                     RQPAPGLGARRPQALHHQWRTWERLRDGLATHLAAGRVTYVSDHHVWCVERDSGRFAVL
                     ALLGPEQREPASVRADGVVLATGGYEKVWPFPGWTLPGVITAGGAQAMLKGGLTLPGRT
                     VVVAGTGPLLLPVATGLAAAGARVAALVESAAPTTLVRRSAHPREAVRVARALAAHPGK
                     LAEAGGYAAQLLRHRIPVRVRRAVVEAHGRDRLESVTVAVLGPDGRPVPGTAQRLDCDT
                     LAVGHGLLPHTDLADGLGCRLDGAGVHVDDEQRTDVPGVWAAGEATGIGGAALSLAEGH
                     IAGRSAAARLNGAAPDPRSWASAARSRTRLRTFFAELDRAYAAPVRWAENVPDATVVCR
                     CEEVTAGAVREAVGSLGAGDLRTVKLLTRAGMGWCQGRMCEPGVAGVAGCDLTPGRRPL
                     ARPVPLGVLAAPPPPDAGTSP"
     gene            complement(17164..17463)
                     /locus_tag="NFX46_RS11700"
                     /old_locus_tag="NFX46_11700"
     CDS             complement(17164..17463)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133599.1"
                     /locus_tag="NFX46_RS11700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11700"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_252548499.1"
                     /sec_met_domain="Fer2_4 (E-value: 2.1e-27, bitscore: 93.8,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPLELVGARPGAPFTVTFDGREIEVLPGQTIAAALWSAGVVAWR
                     TTREGGRPRGVFCGIGVCFDCLVTVDDRPGRRACLTPATPGADIRTQEGTGHDD"
     gene            complement(17460..18668)
                     /locus_tag="NFX46_RS11705"
                     /old_locus_tag="NFX46_11705"
     CDS             complement(17460..18668)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996369.1"
                     /locus_tag="NFX46_RS11705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11705"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_252548501.1"
                     /sec_met_domain="DAO (E-value: 1.9e-58, bitscore: 197.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNQSSCDVVVVGAGMIGAACALYAVRAGLDVVVVDRGPVAGGTT
                     GAGEGNLLVSDKEPGPELELALLSCRLWREITEHRRPDNHRPPTRGHGLAPGLGRAVEF
                     EPKGGLVVASTPGALTALTELAVGQRAAGVETVAVDADQLRELEPYLAPGLAGGVLYPQ
                     DAQVMPTLAAAHLLRASGARVETGRTVTGVLRGAGGAVRGVRTDRGHLLAPAVVNAAGT
                     WGAEVAALADVSLPVLPRRGFVLVTEPLPRRVRHKVYSADYVADVASDSAALQTSPVVE
                     GTAAGPVLIGASRERVGFDRSFSLPVVRALAAGATRLFPFLEHVRAMRAYVGFRPYLPD
                     HLPAIGPDPRAPGLFHACGHEGAGIGLATGTGHLIAQTLTGRTPDVDLTPFRPDRFAEE
                     AAP"
     gene            complement(18840..19694)
                     /locus_tag="NFX46_RS11710"
                     /old_locus_tag="NFX46_11710"
     CDS             complement(18840..19694)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004982493.1"
                     /locus_tag="NFX46_RS11710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11710"
                     /product="hypothetical protein"
                     /protein_id="WP_252556343.1"
                     /transl_table=11
                     /translation="MATGALLATAACSSGDDGAAADSETAAAVAERSVAAQTATPAPTI
                     TESVSATPTATATSPTGTESPSAPLSETGARNALITAADIEDNWVQVKDPQTWRDKLLI
                     GEVDTAQFVTGKADAADCQRLVDALYDETLLGRPSGASALNGFQEGQSRLLYQVAAYEK
                     ASLDKSMDWLTKLPDTCDQFTLTGGDSGERTVQVVEASLPEEGDARQGLTVTVKGTANG
                     DPVTLTLDVAVVRVGDDAITITNGGLDGADEDTTRTAVEQGTERLREVQAGRTPTPTPS
                     NLD"
     gene            20310..21008
                     /locus_tag="NFX46_RS11715"
                     /old_locus_tag="NFX46_11715"
     CDS             20310..21008
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116949.1"
                     /locus_tag="NFX46_RS11715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11715"
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_252548504.1"
                     /transl_table=11
                     /translation="MSVQNVLLSGVVGSTAYGLAHAGSDVDRLGLFAAPTEELHGLHPP
                     KESHVSTAPDRTLHEAAKWCRLALGGNPTVTELVWLPADLYEVRTPLGDELVGIRTTFL
                     SARRVRDAYLGYATQQFRRLLARDDGSFSADTRKRTAKHARHLKRLCGQGYELYTTGRL
                     SIRVDDPESFHRFGEQVADDPETALPLLRRYETAFDEARSVLPEQPDERAADAWLRRVR
                     RHFYTSARSS"
     misc_feature    complement(21042..21057)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.19"
                     /tool="antismash"
     misc_feature    21195..21209
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.84"
                     /tool="antismash"
     misc_feature    complement(21374..21389)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.46"
                     /tool="antismash"
     gene            21427..23472
                     /gene="fusA"
                     /locus_tag="NFX46_RS11720"
                     /old_locus_tag="NFX46_11720"
     CDS             21427..23472
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fusA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125685.1"
                     /locus_tag="NFX46_RS11720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_11720"
                     /product="elongation factor G"
                     /protein_id="WP_252548507.1"
                     /transl_table=11
                     /translation="MRNNLDRHLAAVRNLGILAHVDAGKTTVTERILFATGTTHKRGEV
                     HDGTTVTDFDPQERDRGITIFAAAVSCDWDGHRINLIDTPGHVDFADEVERSLRVLDGA
                     VAVFDAVAGVEPQSESVWRQADRHGVPRIAFVNKLDRTGADLDTAVASIRERLHPVPLV
                     VQLPIGIEDAFTGVVDLLRMRALTWGDGAEAAVEGTVPEELREEALRRRRLLEEAVAER
                     HPAALEEFCDRETLSAETLAEALRDLTRTGDGVVVLCGSAYRNRGIEPLLDAVVAYLPS
                     PLDVPAVRGMHEGVDERRPADPAAPFAALAFKVNATPTGRLTYLRVYSGTIEKGDTVWD
                     ASAGRGERVGRILRVQADRHAQLERAVAGDIVAVIGLKAARAGSTLCAPDAPLVLEPPG
                     VADPVVSVAVEPRRGTDADRLASALARLAEEDPSLTVRTDAETGQTVLSGMGELHLEVA
                     VEKIRRALGLEVNVGRPRVTYRETVGRGVSALVFRHVKQDGGAGQFAHVVLDVEPLEDG
                     FDFRSAVVGGRVPQEYVRAVEAGCRDALAEGPLGGHAVTGLRVTLTDGATHVKDSSEMA
                     FRTAGRLGLREALRACTMVLLEPVVEVTVTVPEDAVGGVLGDLAARRGRVTGSEVRGGA
                     AVVTATVPLAELFGYATRLRSRTQGRGTFTARPTGYAPAPALTAAP"
ORIGIN
        1 cggaagtcga agggggtgcc gacgatgacg atgacgtcgg cgttcgagaa ggcgtagcgg
       61 cgtgagagct ggaagtggtg cgggtcgccg ggagggaggg tgccgcggcc ggcgccgttc
      121 atgtacgccg ggatgttcag ggtgcggacc agttcgacgg ccgcctccgt gccgcgggtg
      181 gtccacacct ggctgcccag caggatggcg ggcttcgagg cgtgggtgag gaggtcggcg
      241 agcttctcga cggcgtcggg gtcgccggcc gagcgggtgg aggcgcggta ggcgccggcc
      301 tgcggcaccc gggccttcgc ggcgggcacc ttggcgtcga ggacgtcgcg cgggatctcc
      361 aggaaggagg ggccgggcgc gccgtggtag cactcgcgga acgccatgga caccatgtcc
      421 gcggcgcgtg cggtgtcggg cacggtcgcc gagaacttgg tgatcggcgc catcatgtcg
      481 acgtgcggca ggtcctggag ggaccccatc ttgtgctggc tgagcgcgcc ctgaccaccg
      541 atcagcagca tcggtgactc ggcgcggaag gcgttggcga caccggtgac ggcgtcggtg
      601 gtaccggggc cggccgtgac gaccgcgcag ccgggcttgc cggtgatgcg ggcgtaaccg
      661 tcggcggcgt gggcggcgac ctgctcgtgg cggacgtcga cgacttctat gccctcgtcg
      721 acgcagccgt cgtagatgtc gatgatgtgg ccgccgcaca gggtgtagat gcgctcgacg
      781 ccctcggctt tgagtgcctt ggcaacgaga tgaccaccgg aaatggcgtc ctgggtgtcg
      841 tcgggcatgg cgaagtcccg tcccttcgta gggggtggaa agctctcgcg gtacattgca
      901 tacagtcgac gaatactgta tgaagcttgt tatcccgcat ccggtgggtg gtgtccaggg
      961 ggcgtgcggc actttcagtc atcggagttc ggcctcgcga tgacttcgca gacgggagcc
     1021 gagatggacc tgtacgagca ccaggcaagg gaactcttcg aggaacacgg catcgcggtg
     1081 ccgcgggcgg aggtgaccga ctcatccaag gaagcgcgcg agatcgcccg caggctcggc
     1141 ggccgcgccc tcgtgaaggc gcaggtcaag acgggtgggc gcggcaaggc gggtggcgtc
     1201 aagctcgccg cggaccccgc ttccgccgaa ctgaccgctc ggcacatcct cggcatggac
     1261 atcaagggcc acacggtcgc cacggtcatg ctggcccagc cggtcgacat cgagagcgag
     1321 ttctacgtct cctacgtcct cgaccgcgcg gccggacgct tcctggcgat cgcctccgca
     1381 gagggcggca tggagatcga ggaggtcgcc gcccgtcgcc cggatgccgt cgctcgtgta
     1441 cacatcgacc cggcccgggg cgtcacgtcg gcgaaggcgg gcgagatcgt cgccgcggcc
     1501 ggactgccgg cgcaggccgt cgacgtcctg gtccggctct ggcaggtgct ggtccgagag
     1561 gacgccctcc tcgtcgaggt caacccgctc gtgcgcaccc ggcagggccg gctggtcgcc
     1621 ctcgacggca aggtcaccct cgacgacaac gcatccttcc ggcagtcccg tcggggcggg
     1681 gccgccgccg agtacggcga cccgctggag gaggaggccg ccgcgaaggg cctcaactac
     1741 gtgaagctgg acggcgaggt cggcatcatc ggcaacggcg cgggcctggt catggccaca
     1801 ctcgacgtgg tcgccggctg cggcgcccgc cctgccaact tcctggacat cggcggggga
     1861 gcgtcggccg gcgtcatggc ggacggactg gcggtcatcc tgtccgaccc ggccgtcaag
     1921 tcggtcttcg tcaacgtctt cggcggaatc accgcctgtg acgcggtagc cgaaggcatc
     1981 gtgcgcggcc tggacaccgt acggctgacc aagccgctcg tcgtccggct cgacggcaac
     2041 aacgcggccc ggggccgcgc gatcctcgac gagcaccggc atcccctggt cgaacaggcc
     2101 accaccatgg acggcgccgc ccgccgcgcc gcccgactcg ccaccgcagc ctgaggagcc
     2161 accatggccg tctacctcac caaggacagc aaggtcctcg tccagggcat gaccggcggc
     2221 gagggcatga agcacacccg gcgcatgatc gccgccggca ccgacgtggt cggcggcgtc
     2281 aacccccgca aggcgggtcg caccgtcgac ttcggcgacc gcgccgtacc ggtcttcggg
     2341 tcggtcgccg acggcatacg gtcgaccggc gccgatgtca ccgtcgtctt cgtcccgccc
     2401 gccttcgcca agtcggccgt caccgaggcc gccgacgcgg gcatcgggct cgccgtcgtc
     2461 atcaccgagg gcatcccggt ccacgactcc gtcgccttca ccacgtacgc cagggcgcgc
     2521 ggcacccgcc tcatcggccc caactgcccc ggcctgatca gcccgggcca gtccaacgcc
     2581 ggcatcatcc ccgccgacat caccaaaccc ggccgcgtcg gtctggtctc caagtcgggc
     2641 acgctgacgt accagctcat gtacgaactc cgcgacgtcg gcttctccac ctgtgtgggc
     2701 atcggtggcg acccggtcgt cgggaccagt cacatcgact gcctggccgc cttcgaggac
     2761 gacccggaca ccgatctcgt cgtcctcatc ggggagatcg gcggcgacgc ggaggaacgg
     2821 gccgccgcct atgtccgcga ccacgtcacc aaacccgtcg tcggctacat cgccggcttc
     2881 accgcgcccg agggcaggac catgggccac gccggcgcga tcgtctccgg ctcctcgggg
     2941 accgcgcagg cgaagaagga ggcgctggaa gcggccgggg tgcgagtggg gagcacaccg
     3001 acggggacgg cgcagctcgt gctcgacctg ctcggcaacc ggacctgacg tccctcaccg
     3061 cgcgggcacc gaccggcgcc cgcgcccacc ccttccccct cgtccccttc ccctcctttc
     3121 ccctcccccc tttcctctcg accgtgcacc gagagcggag tgaccgcatg gcatccaccc
     3181 tcaccctcaa atccggcacc tcctgggccg acgcctggcg gcgctgcctc accgccgccc
     3241 ccgaggcctt ccgcgaggac cgcgtcctca acctctggaa cggtgcctgg caggccgacg
     3301 gcaggaccct gcccgccacc agcccggtgg acggcagtcc cgtcaccgga ccgccgcgcc
     3361 tggaccggga caccgcccac caggcggtcc gcgcctccct ggaccagcac cgcgcctggc
     3421 gccacctccc gctgaccgaa cgccgcgccc gcgtcgccgc caccctcgac gccctcgccg
     3481 cccaccgcga actcctcgcg ctgctgctcg tctgggagat cggcaaaccc tggcggctcg
     3541 cgcaggcgga cgtcgaccgg gccgtcgacg gggtgcgctg gtacgtcgac ggcatcgagc
     3601 cgatgctggc cggccgggcc ccgctggacg gcccggtgtc caacatcgcg agctggaact
     3661 acccgatgag cgtgctcgtt cacgcggtac tggtccaagc actcgcgggc aacgcggtca
     3721 tcgccaagac cccgaccgac ggcggcgtcg cctgtctcac cctggcctgc gccctcgccg
     3781 cccgcgaggg catcccggtc accctcgtca gcggcagcgg gggcgagctg tcggatgcgc
     3841 tggtgcgggc gcccgagatc ggctgcgtct ccttcgtcgg cggtcgcgac accggcgccg
     3901 ccgtcgccac cgccgtgacg gacctcggca aacgccacat cctcgaacag gagggactca
     3961 acacctgggg catctggaac cactcggact gggacaccct cgcggccctc gtccccaagc
     4021 tcttcgacta cggcaagcag cgctgcacgg cgtacccgcg cttcgtcgtc cagcgcgagc
     4081 tgttcgacgc cttcctcgcg gcgtacctcc cggcggtgcg cactctgacg gtcggccacc
     4141 ccctggccgt ggagaagcgc gacgacccct acccccgcct ggacttcggg ccggtcatca
     4201 acgcggccaa ggccaaggaa ctgcacgacc aggtcgccga ggccgtcgac cggggagccg
     4261 tcccgctgta ccgcggcgac ctggcggacg cgcgcttcct gcccggccag gacacctccg
     4321 cctacgtccg tccggtcacg ctcctcaacc cgccgccgtc gtcgccactg caccacgcgg
     4381 aacccttcgg cccggtcgac accatcgtcc tggtcgacac ggaggcggaa ctgctcgccg
     4441 ccatgaacgc ctccaacggg gcgctggtcg ccaccctgtc caccgacgac cgcgccacct
     4501 acgagcgact ggccccgcag atccgcgcct tcaaggtcgg ccacggcacg cctcgctccc
     4561 gcggcgaccg cgacgaactg ttcggcggct tcggggcctc ctggcgtggc gcgttcgtgg
     4621 gcggtgagct gctcgtgcgg gcggtgaccc gaggaccgac ggacgagcgg ctgccgggga
     4681 acttccccga ctaccagctg atgccctgaa gcgggccgcg gggcggcgca cctgacgggc
     4741 gccgccccga gtcaccctcg tgcaccagcg gttaccctcc ctgcgtggtc cgtgaccgcg
     4801 acccccaccc gccgcccctc gaactgcgtc acccgggccc actgctagga cgggcccaga
     4861 gccggctgac cgggatcacc acggagacgc tcgtatcgca cggggtggac gggcgcgagc
     4921 cggcgggcct cgccgtgccg gccgacgggg cggagctgtc gcaggccgac gccaccgccc
     4981 ggcccggagt cgaccgcacc acgatggtgt cgctcaccga cggaccggag gaccacgggc
     5041 tcgtggagcg gcggcccagt ccgtacgacc gccgcaggaa cgtcgtcgcg ctgacggcgc
     5101 cgggcgagga gtgcctgctc caggcggagc gggcgcgccg cgcggcggag catcgcttcc
     5161 tcgcaccgcc gagcgaagaa gcggcgacgg ccctgctgcc ggcgctgcgc acgccggccg
     5221 cggaggagga tcccgccacc ggacgcccgt cactgtccgc acacgccggg tgaccccggg
     5281 agccggaccc tgcccggaca cccgcgcagg cccccggcca gcggatactc gggtgaaacg
     5341 cactccgaaa gcttggtatc gttgtccatg tcgccacggg ggaacacccg cggcggcaga
     5401 cacctggtcc gggtggcgga atggcagacg cgctagcttg aggtgctagt gccctttatc
     5461 gggcgtgggg gttcaagtcc cccctcggac acttatcacc ctccgtatcc agcggtttcc
     5521 gctcggtgag gaaagtgcgc ggagagctgc cgtgcagaag tcacccgcat ccgggattcc
     5581 cgggtgcggt tttgtcgttt ctttacccgg tggtttccgg gaaatcgttc cgaacgcctc
     5641 gattgcctcc cgaatgccgc ggaagcccgt ttatcggttg cgtcggaagc ggcccgcccc
     5701 gtggtcactg acgaaccgtc aatgttcatc tggggcaccc acgttggctg tctgtgatcg
     5761 catcgtgtgg tgatacgatc acggcgcttg tagagcgggc ggatgggtga aggacgacat
     5821 ccccgactac ggggacagtc cgggcggtgg ccccgatgcg ggcggtcccg ccggtccacc
     5881 cgcattgacg ggaattcagc atctggccgt cagtcgcctg aagagagtct tatgactgat
     5941 tacatacaga acccggtact ctgggctctc ctcatcgccg tactcgccgc cgtcgccctc
     6001 attgttcgtc agcggagggc ggcgcggacg ttaaggcagg agttcgcaga tctcagggct
     6061 cggcacgacg agctggagaa cgggtacgcg aaatccgtcg aggcagctca ggaaagagcc
     6121 gacgaggcta cgaaaacagt cctgaagtcc gccatgcgga cccttcaggg ccttgccgcg
     6181 gaacagcagt tgattgtctc ccggctccag aagaaatacg gcgagtcggt catcctccag
     6241 gaccttctgg agatcgacca cacgaactcc cagttcggcc gccgggccca gtccatcgcc
     6301 gtcctctgtg acggctggct gggtcgtcag cgcgatgtgg cgtcggtcta cgacgtggtc
     6361 cgcagcgcgc agggcaggat ccgccactac cggcgggtgg aaattctctc gcaggtcgat
     6421 ttcggcatca ccagccgtgc ggtggaaccg gtcgcactgg ccctcgccga aatgcttgac
     6481 aatgcgacca gctattccag cccggacacg gttgtcgaaa tcaacattcg taccgtgccc
     6541 aagggtatct gtatcgtcgt ggacgacgcc ggtgtcggca tgaacgacga ggagcgggcc
     6601 cgcgcggaga aactcctctc cagcgaccgc gtctcgggcg tctcccggct cggcaacccg
     6661 ccgcagttcg ggttcgcggt gatcggtgtc ctcgccgagc gcttcggctt cgaggtgtcg
     6721 gtggactcca cgtcgcccta cggcggcgta cgcgcggtcc ttctcctgcc gcacgacctg
     6781 ctcaccaacg cacccgagca gaaggaaccg acgccggccg ctcccgccgt cgccgcaccc
     6841 acccgcggcg gtcccgagcc cggcccggcc ccgagcacca ccgtcgacgg gctgcccaag
     6901 cggcgccgca aacggccgat ggccatcgtg cccggcagtg ccccgaccgc cgccgcgccc
     6961 tcccgctcgg gtgcggagac cgcggcgatc atgggcgcct tccagcgagg cacccagtcg
     7021 ggccggcggg ccacccctgc ggaccccgcg gaacagtcca gcagtacacg tggcgcaagc
     7081 agcgaagggc atgagttctc gtgaacgacg atctgtcatg gatgcttgac agcgccctgg
     7141 agattcccgg ggccctgcac gccgtcctga tatccgccga cggcctgttg atggcccgga
     7201 cgcaggacat cgggaaggac gatgcggacc gcgtggccgc cgccatgagc ggggtccagt
     7261 cactcagccg ctccctggcc ttcttctgcg aggacgccca gcagcggtgg cggcagacac
     7321 tggtcgagtt cgacggcggc tgggtcttcc tcatctccgc cggcgagggc gcctacctcg
     7381 gcgtctccgc ctcgcccgat gtcgacatgg cggacatcac gttccggatg cagcagctcg
     7441 tcggccagct cggcaaggcc ctgacgacac cgccgcgcga gaacctcggc gtgcggtcat
     7501 gaccggtttc gacgaactgg agccccagac gccggagtta gttcgtccgt acgtcatcac
     7561 caagggacgc ggactgcccg acgaggagca gctctccctc atcactctgg tgacggcggt
     7621 cgccgaccgc cagcagcggc cgacccggct gtccccggag gagcagagcc tgctcgagct
     7681 gtgctcggcc ggctacctgt cggtcgccga gatcgcgggg cacacccaac tgcccctcgg
     7741 cgtggtgaag atcctcctcg ccgcgctcac cgagggcggc tacctcatca cccgcccgcc
     7801 ggtgcagcgg gcgcctgtcg ccgaccggga gatcctggag gaggtgctga atggtctcag
     7861 ggccaagttt ggatgaacag gcgtacgtcc gtgagggcgc gtcgcagacg gccgtgaaga
     7921 tcctcgtcgt cggccacttc gcggtgggca agaccacgtt catcggggcg atctccgaga
     7981 tccccccgct gtccaccgag gagacgatga cgcgggccgc ggaggccgtc gacgacctca
     8041 agggggtcca gggcaagacc accaccacgg tcgccatgga cttcgggcgc ctgaccatca
     8101 gcgaccgggt cgtgctgtac ctgttcggga cgcccggcca gcagcggttc gtgcagatgt
     8161 gggaggacat ggcccgcggc gcgctcggcg ccctggtcct cgtcgacccc gaacggctcg
     8221 cggactcgtt cgccgtgatc gacctgatcg agcagtacgg gctcgactac gccatcgccg
     8281 tcaaccactt cgacggctcc cccctgcggg acgagaccgc cctgcgtgac gcgctggacc
     8341 tgctcgacga cacccccgtc gtcacctgcg acgcgcgcga cgagcagtcg tcggccgaag
     8401 cgctcatcac tctcgtccgc cacttgcagg accgtgccca ctaggagcag aaatggacca
     8461 acccaccgct ccggtgcccc cgcccgggtg cccggcgcac aacagcggcg cgcgagtgcc
     8521 gctccacggc cccgagttcg cggctgaccc gcaggcctac tacagctatc tgcgccacta
     8581 cgggccgacc gccccggtcg aactcgcccc cggcgtcgag gccacccttg tcaccgacta
     8641 cgccaccgcc ctgcaactcc tgcaggactc gggctcgttc cgcaaggacg cgcgccgctg
     8701 gcggcacttc aacgagggca agatctcccc cgacagcccc gtcgcgcccg tgctggccta
     8761 ccggcccaac tgcatgttca gcgacggcgc cgagcacctg aggctgcgcc aggccgtcac
     8821 ggacagcatg gcccgcatcg acacgcgcaa gctgagccac agcaccgagc aggtctccaa
     8881 ctacctgatc tcccagttcg cttcgcgcgg ctcggccgac ctgctcggcg actacgccaa
     8941 gcagctcccg ctgttcgtgt tcaacgaact cttcggctgc cccccggaca tcggcgaccg
     9001 cgtcgtctac ggcatcaccg gcatgttcga cggcatcaac cccgcccgcg cgatggaggt
     9061 gctgttcggc gccgtcggcg aactcgtcgc gctcaagcgg gtcaagcccg gcgaggacgt
     9121 cacctcctgg ctgatggagc accaggcggc gctcaccgac gaggagatgg ttcaccagct
     9181 ggccctcctg ctggtgggag gcaacgagcc gctgcgcaac ctgatcggca acaccctgca
     9241 ccggctcctc acccacgacg cgtacgccaa ccagggcggt ctgatcgacg aggcgatcga
     9301 cgacacgctg tgggagaacc cgcccatgca gaacctcgcc ccgcactacc cggccgccga
     9361 catggagttc gccggacagc agctccaggc gggcgacctg ctcctggtca gtttcgccgc
     9421 cgccaacacc ggccccgcgc tgacggccgc ccggcaggcc ggcagcaacc gcgcccacct
     9481 ggcctggagc gccggcccgc acgcctgccc gtccaaggac ccggcccggc agatcaccgt
     9541 gacggctctg gagaacctcc tcaacaagct tcccgacgtc gaactcgccg tccccgagga
     9601 gagcctgacc tggcgccccg gccccttcaa ccgggggctc atcgcgctgc ccgcccggtt
     9661 caccgcggtg accgagcgca agcccgcccc cgaggcgcgc accgaggccg cccgccctga
     9721 gcagccccag ccgggcaccc gcgccgaacg ctcgggtgtg tggagccagt tcctcaactg
     9781 gctcacgagg tgattcacac aacacaggcc aactcttcac gttcgtatga cggttcaacc
     9841 tcaggggtag tgagccatgc ggtaacccgc atatcccacg agcccgagga gttgccgtgg
     9901 accacatgtc caccgacacc gttccccgtc cacatcccgc agcgttgagc ctcgagatac
     9961 ccgccctcgc cggcgggtat ctccttgtcg gctccggccc gtggcgggag agccggtgac
    10021 ggccgcccgg cccggcgggc cgagacgctc cggcacggaa acgctcggcg gccacacgag
    10081 ccgccaactg cggaacctgt gcgagatcgt gggactcacc gcccatgacg gcgaggtcta
    10141 cgcgcgtacc ctcaccgaga tgctgggtgc cgccgccgag cggccgctcg acctgccgcc
    10201 cccgaacccg acgttcctct ccgacgacca caccccggtg gagttctcgc tctccttcgt
    10261 gcccggtgcc gcgcccaccc tgcgggtgct gctcgaaccg ggttgcgcgg ccggcggcct
    10321 ggcacggaac gggcgtctcg gactgcgggc cgtccgcgag acgacggccc gctggggctt
    10381 cgccaccgac cggctcgacg aactggagga cctgttcctc ccgccctcgc ccgagggccc
    10441 cctcgccctg tggtgcgcgc tggaactgcg tcccggcggc gtccccaagg tcaaggtcta
    10501 cctcaacccc gcggccggcg ggcagaaacg tgccgccgcc acggtgggtg aggcgctgcg
    10561 gcggctcggc caccgggacg cgttcgccgc gctgccgccg cacgaccgcc acctgttctt
    10621 cgccctggac ctgggcgact gggcggagcc ccgggtgaag gtctacctcg cccaccagga
    10681 cctgtcggcc gccgaggcag gcgccctgtc ccggatggaa ggcggtcccc tcgccgcgga
    10741 gagcgaggag ttcttccgca tcgcctcagg tcaggacggt gatgaggagg gcggcggcac
    10801 ggcttcggca ccggtggtgc ggcgccccgt acagtcctgc cacgccttca ccgagaccgc
    10861 gtccggcctg cccagcggct tcaccctcta cgtccccgtc cgcgactacg cgcggcacga
    10921 cggcgacgcc ctcacccgtg ccaccgccct gctcggccgc tacggacagg acccggcccc
    10981 gctgctgggc gccgtgtccg cggtcaccga ccgcagcccg gaggacgggg tgggactggt
    11041 cgcctacctg gcactcgccc accagcaggg gcagccgccc cgggtgacgg cgtacgtctc
    11101 ctccgaggcg tacgaggtgc gcccgcccgc cggcctgctg cccgccgagc ctgcgaccgt
    11161 gcggtaacgg gcgctgccgg gggacatctc gcgggggagc cgtacgccga cgacgtcgaa
    11221 ccgctccctc tccgccgcga cggccggcaa cgcgggcgga ccgggggagc cgggggccac
    11281 ggaacgacga gggggccggc cacgggggag cccgccacct gccgacccca ggccgacgcg
    11341 cctacccacc gaccctcata cgtcctgcag ttcctggagg tacggtgcca cgttcacctg
    11401 gatcgaggcg ccttccgcct gcccgtactg gcccgcgatg ccgctcaggt agatggcgac
    11461 ctccttgcgc atgacctccg gctcgggcag aaccgccgcg cccgagacga tccgcgcgat
    11521 ccagcgggac tgcgcctcca cgagccgcgt gatggagccg tgcgggcgga ccaggcccac
    11581 gaagtacagg ccggcatggc cgggcgcgac gacccgtttg tacagctcca ccgagccccg
    11641 ctccccgatc gggcagccgg acggcaggaa cgggaacgcc atgcggtagc cggtgcagtg
    11701 cacgatcgcg tcggcccgcg cggacgaccc gtcggtgaag accacccggt cgcggtcgag
    11761 cgaggcgatc gcgggcttgg ggacgacccc gccgtgccgg atgcgggtga ggatctcgtc
    11821 cgagatggtc acggccgagg cgaacaccgg gtggtccggc tcgggaagcc cgtagtccga
    11881 gagcctcccg cgggccacga ggagggcctg ctcgatgaaa cggcgctgct ccgccagcga
    11941 catgctcgtc caccacggcg cctcggcgac ctcgtcgagc gggatgccga acaactgctt
    12001 gggcaggatg tgcagacccc ggcgcaccga gagcagggtg gtcgccgcgt accgggacag
    12061 gtccgccgcg atgtccaccg ccgaggcacc gagcccgacg acgaccaccc gctgaccggc
    12121 gtagtcactg ccgtcgcggt agtccaaggc gtgcagaatc gttccggtga aggtgtccga
    12181 gcccggaggc ggcgcgggca gggacggctc ggtgttgtgc cccgaggcga cgacgacatg
    12241 cgagaagctc cgcgcgccgc gcgtgccccc ggcatccacg gcgacgaccg tccacgaacc
    12301 gtcggcctcc tgccgcaccg actcgacgga cgtccccagc tcgatgtggt ccaggacgtc
    12361 ggcccactcg gcgaacgcac gcaggtagga ggcgacctgg ctgtgccgtg ggtagaccgg
    12421 gtaggaggcg ggcatcgggt agtcggcgta acccgtcagc cccttggtcg tgttgaggtg
    12481 cagcgacagg taacccggcc cccgctcacc ggcctcgggg cggcgccaga tgccgcccac
    12541 gtcccccgac ctctccagac acacgaagtc gacacccgcc gtttcgaggg cccgtgccgc
    12601 ggccagcccc gacaggcccg caccgatcac acacacactc acggattccc ccacaggaaa
    12661 gacacgacct ctacggacac gcgcagtgcc tgcccatcgg gtacttcccg caaccagcga
    12721 caaagatcac acaggtcaca tgtgggacag ggggtcggcc cgtccggcta cgcgtcggcg
    12781 gacgcccaca gcccccgtac gtgcccgagg tgccgggtca tcaccgtgcg caccgcccgc
    12841 tcgtcgcggg ccagcagggc gtcgaggagt tccaggtgct cctcggcgga cgccagcagc
    12901 cgaccggagg cggacagggc ggtgagcccg tagaggcggg cacggccacg cagatcacgg
    12961 accacctcga ccaggtggga gttgcccgcc agggccagga ggcccaggtg gaagcgggtg
    13021 tcggcctcga cataggcgat caggtcgccc gccacggcag cggtgacgat ctcccgggcg
    13081 gccggacgca gcgcctccag cgacaccggg tcggcggtcg tcgccagcgc caccaccgtc
    13141 gggatctcga tgagcgcgcg gacgtgtgtg tactcgtcga gctgccggtc ggagacgtcg
    13201 gtgacgcgga agcccttgtt ggggaccgcg tcgaccagcc cctccttcgc gaggtccagc
    13261 atcgcctcgc gcaccggggt cgccgagacg ccgaagcggg cggccagcgt gggcgccgag
    13321 tacacctggc cgggccgcag ttcacccgcg atcagcgcgg cccgcagcgc gtcggcgacc
    13381 cgctcgcggt agctgctccg ccgcccaccc agcacgggca gcgcgggcgc ggcgggggag
    13441 gggctgatgc tgcgcggggc ggccatgcgg gatctcctcg gaacgggcgg tgtcatctca
    13501 ctcggcatgg actgtgccat gtcacgtgcc atcagtatcc acggcgctct cccggcgtac
    13561 ggacggttcc gcgccgccgg cggtggacgc cggtggtcgg agcgtgagac tcggcgggcg
    13621 gtggacgccg gtggtcggag cgtgaggttc ggtcggcggt ggacgccggt ggtcggagcg
    13681 tgagactcgg cgggcggtgg acaccggtgg tcagagcgtg aacccggccg ggaacgggtc
    13741 cgtcggatcg agcaggtact gggccgtgcc ggtgacccat gcgcggcccg tgaaactggg
    13801 cagcacggcc ggcaccccgg cgacctccgt ccggccgagg agccggccgg tgaagcgggt
    13861 gccgatgaag gactcgttca cgaactcggt gtgcaggggc agttcaccgc gtgcgtgcag
    13921 ttgcgccatg cgggcgctcg tccccgtacc gcagggggag cggtcgaacc agcccgggtg
    13981 gatggccatc gcgtgccgcg agtggcgggc ggtggcgccg ggggcgtaca ggtggacgtg
    14041 gtggcagccg tggatcgacg ggtcctgtgg atgcaccggc tccccctcgg cgttgatcgc
    14101 ctccatgagg gacagcccgg ctcgcaggat gtcgtccttg cgggaccggt cgaagggcag
    14161 cccgaactcc tccagcggca ggatggcgta gaagttgccg ccgtaggcca ggtcgtacgt
    14221 caccgttcgg ccgtcgggca gggtgatctc gcggtccagg gccacggcga aggacgggac
    14281 gttgtgcaat gtcaccgccg tggccgcgcc gtcccgtacc gcgacctcgg cgacgacgag
    14341 cccggccggg gtgtccagcc ggatggtggt gaccggttcg acgacctcga ccatgccggt
    14401 ctccaccagc acggtcgcca ccccgatcgt gccgtgcccg cacatcggca gatagccgga
    14461 gacctcgatg tagacgaccc cccagtcgca gtccgcccgg gtcggcggct ggaggaccgc
    14521 gccgctcatc gctgagtgac cacgcggctc gttcatcagc aactgccgta cctcgtcgcg
    14581 gtgttcacgg aggtacagcc gccgttcgtt catcgtcgcg ccgggaatgg tgccgattcc
    14641 gccggtgatc acccgggtgg gcatgccctc ggtgtgcgag tcgacggcgt gcaggacgag
    14701 tttgctgcgc atgaagtgcc tttccgggcg gtggggttac gccaggcccg cggcgacggc
    14761 cttctcggtg gccgcgcgga cggcagcctc ctgctcggga ggcagcggta cgcgcggcgg
    14821 ccggcagggt ccgccgtacc ggccgacgac gtccatcgac actttgatgg cctggacgaa
    14881 ctcgacgcgc gagtcccagc gcagcaacgg gtgcaactgc cggtacagcg gcagcgcggt
    14941 ggtgaggtcc cccgcgacgg cggcccggta caggttcacc gaggcgcggg gcagcgcgtt
    15001 ggggtagccc gccacccatc ccttggcgcc cgccaccgcc agctccagca gcacgtcgtc
    15061 cgcgccgatc agcaggtcca gttccggtgc cagttcggcg atccggtagg cgcggcggac
    15121 gtcgcccgag aactccttga cgccgtggat gaggccctcg ccgtgcagcc gggccagcag
    15181 ttcgggcacc aggtcgacct tggtgtcgat ggggttgttg tacgccacca ccggcaggcc
    15241 cgcctgggcg acctccgtgt agtgcgccac gaccgcgccc tcgtcggcgc ggtaggcgtt
    15301 gggcggcagc agcatcaccg caccgcagcc cgcctcccgc gcctgctcgg cccagcggcg
    15361 ggcctccgcc gagccgtacg cggcgacccc gggcatcacg cgctccccgc cgatcgccgc
    15421 gaccgcggtc cgtacgaccg cggcacgctc ctcgggcgtg agtacctggt attcgccgag
    15481 ggagccgttc ggtacgacgc cgtcgcagcc gttcgccacc agccaggcgc agtgctcggc
    15541 gtaacggtcg aggtcgacgg agaggtcgtc gcggaggggg agggcggtgg cgacgaggac
    15601 gccatgccag gggcgggggg tggtcatgtg gggtctgcct ctctctcacg gtgctggtgt
    15661 gtgacatagc actgcgggtg gcgggtggcg ggtggcgggt ggcgggtggt ggggtgagcg
    15721 gcggctccgg gtcaggggct ggttccggcg tccggtgggg gcggcgcggc caggactccg
    15781 agggggacgg gacgggccag cggccgtcgg ccgggggtga ggtcgcagcc cgcgaccccc
    15841 gcgacacccg gctcgcacat ccggccctga caccagccca tcccggcccg cgtcagcagt
    15901 ttcacggtgc gcaggtcgcc cgcgcccagc gagccgacgg cctcgcggac ggcgcccgcc
    15961 gtgacctcct cgcaccggca caccaccgtc gcgtccggca cgttctccgc ccaccgcacg
    16021 ggcgccgcgt acgcccggtc cagttcggcg aagaaggtcc gcagccgggt gcgggaccgg
    16081 gcggccgagg cccaggagcg cgggtcgggt gcggcgccgt tcaggcgggc ggcggcggag
    16141 cgtccggcga tgtggccctc ggcgagcgac agggccgcgc cgccgatgcc cgtcgcctcc
    16201 ccggccgccc acacgccggg gacgtcggtg cgctgctcgt cgtcgacgtg cacccccgcc
    16261 ccgtcgaggc ggcagccgag tccgtccgcg aggtcggtgt gcggcagcag gccgtgtccg
    16321 acggcgaggg tgtcgcagtc caggcgctgt gcggtgccgg gcaccgggcg gccgtccggg
    16381 ccgagtacgg cgacggtgac ggactccagc cggtcccggc cgtgggcctc gacgaccgcc
    16441 cgacgcaccc gcaccgggat tctgtggcgc aggagttggg ccgcgtagcc cccggcctcg
    16501 gcgagcttgc cggggtgagc ggccagggcg cgggcaacgc gtacggcttc ccgagggtgc
    16561 gcggatcgac gtacgagagt ggtcggggcg gccgactcca cgagcgctgc gacgcgggcg
    16621 cccgccgcgg cgaggccggt cgccacgggg agcagcagcg ggcccgtccc ggcgaccacc
    16681 accgtgcggc cgggcagcgt gagcccgccc ttcagcatgg cctgggcgcc gcccgccgtg
    16741 atcactccgg gcagcgtcca gccggggaac ggccacacct tctcgtagcc gccggtcgcc
    16801 agcaccaccc cgtcggcacg gaccgacgcc ggctcgcgct gctcggggcc gagcagtgcg
    16861 agcacggcga agcggcccga gtcccgctcc acgcaccaca cgtgatggtc gctcacatag
    16921 gtaacacgtc cggccgcgag gtgggtggcc agcccgtcgc gcaggcgctc ccacgtccgc
    16981 cactggtggt ggagggcctg cgggcggcgg gcgccgaggc cgggggcggg ctgccggtag
    17041 aactgtccgc ccggctcggc ggcggagtcg acgagcacca cgcgcacccc tcgcgcggcg
    17101 gccgccagcg cggcggcgag gcccgccgga ccggcgccga tcaccgcgag cacctgccgc
    17161 cgctcagtca tcgtggcccg tcccttcctg cgtacggatg tcggcgcccg gcgtggcggg
    17221 ggtcaggcat gcgcgccggc cggggcggtc gtccacggtc accaggcagt cgaagcagac
    17281 accgatcccg cagaacaccc cgcggggacg gccgccttcg cgggtggtgc gccaggcgac
    17341 gacgcccgcc gaccagagcg cggcggcgat cgtctgcccc ggcagcacct cgatctcccg
    17401 gccgtcgaac gtgacggtga acggcgcgcc gggacgggcc ccgaccagtt ccagggggtt
    17461 cacggcgcgg cctcctcggc gaagcggtcg gggcggaacg gggtgaggtc cacgtcgggg
    17521 gtcctgccgg tcagcgtctg cgcgatcagg tggccggtgc cggtcgccaa cccgatgccc
    17581 gccccctcgt gcccgcaggc gtggaagagg cccggcgcac gcgggtccgg accgatcgcc
    17641 ggcagatggt cgggcaggta ggggcggaag ccgacatacg cgcgcatcgc ccggacgtgc
    17701 tccaggaacg ggaacaggcg ggtcgccccc gccgccagtg ccctgacgac gggtagggag
    17761 aacgaccggt cgaagcccac ccgttcccgg ctcgcgccga tcagcacggg cccggccgcc
    17821 gttccctcga cgaccggcga ggtctggagg gcggcggagt cgctggcgac gtcggccacg
    17881 tagtcggcgg agtacacctt gtgccgcacc cggcgcggca acggctcggt gaccaggacg
    17941 aatccccggc gcggcaggac cggcagcgag acgtccgcga gcgcggcgac ctccgcgccc
    18001 caggtcccgg ccgcgttcac cacggcgggc gcgagcaggt ggccgcggtc ggtccgtacg
    18061 ccccgcaccg ccccgccggc gccgcgcagt acgccggtca ccgtacgacc ggtctccacc
    18121 cgggcgcccg aggcgcgcag caggtgcgcg gcggccaggg tgggcatgac ctgggcgtcc
    18181 tggggataca ggacaccgcc cgccaggccg ggcgccaaat atggctccag ctcccggagt
    18241 tggtcggcgt cgacggcgac cgtctcgaca ccggcggcgc gctgtccgac cgccagttcc
    18301 gtgagggcgg tgagtgcccc gggggtggag gcgacgacga ggccgccctt gggctcgaac
    18361 tcgacggcac ggccgaggcc gggagcgagg ccgtggcccc gggtgggtgg gcggtggttg
    18421 tccggccgtc ggtgttcggt gatctcgcgc cacaaccggc aggacaagag ggccagttca
    18481 agctccgggc ccggctcctt gtcggagacg aggaggttgc cctcacccgc tcccgtcgtg
    18541 ccgcccgcca ccggaccccg gtccaccacg acgacgtcca gtccggcacg caccgcgtac
    18601 agcgcgcagg cggcgccgat catgccggcg ccgacgacca cgacgtcaca ggacgattgg
    18661 ttggtcactc cagtaatatg tcacatggtc ctggcgaggg gaacaggccg acggagcgct
    18721 cccgttcagc cgggcggggg gccggccgcc ggctgacagg gcgttccggt gaggtggggt
    18781 gtggcgaggt ggcgggcgga gtggcgggcg gaggtggctc gctgagccgg gaccatcgct
    18841 cagtcgaggt tgctcggcgt cggggtcggc gtacggcccg cctggacttc ccggagccgc
    18901 tcggtgccct gttccacggc ggtccgggtg gtgtcctcgt cggcgccgtc gagcccgccg
    18961 ttggtgatgg tgatcgcgtc gtcaccgaca cggacgacgg cgacgtccag ggtgagcgtc
    19021 accgggtcgc cgttcgcggt gcccttcacg gtcacggtga gaccctgccg ggcgtcgccc
    19081 tcctcgggca gcgaggcttc gacgacctgg acggtacgtt cgccgctgtc gccgccggtc
    19141 agggtgaact ggtcgcaggt gtcgggcagc ttcgtcagcc agtccatcga cttgtcgagc
    19201 gaggccttct cataggcggc gacctggtac agcagccggg actgcccctc ctggaagccg
    19261 ttcagcgccg acgccccgga cggacggccg agcagcgtct cgtcgtagag cgcgtcgacc
    19321 aggcgctggc agtcggccgc gtcggccttc ccggtgacga actgggccgt gtccacctcg
    19381 ccgatgagca gcttgtcgcg ccaggtctgc gggtccttca cctgcaccca gttgtcctcg
    19441 atgtccgccg cggtgatcag cgcgttgcgg gcgccggtct ccgagagggg ggcggacggc
    19501 gactcggtgc cggtcggcga cgtggcggtc gccgtcggcg tggcgctgac cgattcggtg
    19561 atggtcgggg ccggggtggc ggtctgcgcg gcgacggacc gctcggcgac cgcggcggcg
    19621 gtctccgagt cggccgccgc gccgtcgtcc ccgctggagc aggccgccgt ggcgagcagc
    19681 gcgccggtgg ccatcgcggc ggccaggaca cgggccgggc ggaccgggtg cgccgcgcgg
    19741 gcccgacggc cctccgtgcg ggatacggcc gtgacgggag tggccgggtc cggcgcggcg
    19801 gcagcggtct tcgccgtgcg ggacgggcgg ccggtcgggc gaggggtgat cacgtatgcc
    19861 tcctgaggac ggaacggggt cccggcgcac gtgtgccccg ggcggctccc acttgcctcc
    19921 caccgcacca ccggcccgcc cacgcgacca gcgcagcggg tcatacgggt gagggcatgc
    19981 tcctcgcgcg gcgtggcgcc gagcagaccg gtggcgtggc gcggagcaga ccggtggcga
    20041 ggcacggagc agaccggtgg cgaggcacgg agcggacctc tggcgggggg cctctggcgt
    20101 ggcgccgttc agacggtagc gggggcccga gtgaccttct ggcggggccg gccgagcgag
    20161 ccggtggcgg ggcgccgatc gggcctgctt cggctccctg cgggaccgcg gcggccggaa
    20221 aatgcaaggt ggccgggccg gtcgccgggg catcatgacg actcccgccg ccttctcgcg
    20281 gcggcggacg atgagcaccg ggggagtcca tgagcgtcca gaacgtcctg ctgtcaggcg
    20341 tcgtcggctc gaccgcgtac gggctcgcgc acgcaggctc cgacgtggac cggctcggtc
    20401 tgttcgccgc gcccaccgag gagttgcacg gcctgcaccc gccgaaggag tcccacgtca
    20461 gcacggcacc cgacaggacc ctgcacgagg ccgcgaagtg gtgcaggctc gcgctcggcg
    20521 gcaaccccac ggtcacggaa ctcgtctggc tgcccgccga cctgtacgag gtccgtacac
    20581 cgctcggtga cgaactcgtg ggcatccgta cgacgttcct gagtgcccgg cgcgtccggg
    20641 acgcctatct cggctacgcc acccagcagt tccgcaggct gctcgcccgt gacgacggct
    20701 ccttctccgc ggacacgcgc aagcggacag ccaagcacgc ccggcacctc aagcgactgt
    20761 gcggacaggg ctacgagctg tacaccacag ggcggttgag catccgcgtc gacgacccgg
    20821 agagcttcca ccggttcggc gagcaggtgg cggacgatcc cgagaccgcc cttcccctgt
    20881 tgcgccggta cgagacggcg ttcgacgagg cgcgcagcgt gctgcccgaa cagcccgacg
    20941 agagggccgc cgacgcgtgg ctgcgcaggg tgcggcggca cttctacacg tcggcgcggt
    21001 cgtcctgaga gaccgcttcg accggcattt gtccggggcg tgggaaaaac acgtgcggcg
    21061 cacgtccgtt cctccctaca ctcgccccat cgagcgccgc ccacgagcag ggtcgcgccg
    21121 caccgcgacg aacgaggggg gcccggccat gcgtgaccgc accgctgccg ccgcttcccg
    21181 ttcccgctac gaggtgatcc tcgtgtcctc gtccgtccgg tgtccgcggc gcggccggca
    21241 ccggatggtc tgacgagacc ccagtcctca cgacagagct gccccggcga cttcccgccg
    21301 tggccgtagc cctgtcgtcg tgccagctgt cccccgagcc gtcatccggc tgcccggggt
    21361 cagctgacgt cccgtcaaac aatcgcgcgt ccctttcacg agacacacct cgaaaggcca
    21421 cgggccgtgc gcaacaacct cgaccgtcat ctcgccgccg tccgcaacct gggcatcctc
    21481 gcccacgtcg acgcgggcaa gaccaccgtc acggagcgga tcctcttcgc caccgggacc
    21541 acgcacaagc gcggtgaggt ccacgacggt acgaccgtca ccgacttcga cccccaggag
    21601 cgcgaccgtg ggatcaccat cttcgccgcg gccgtcagct gcgactggga cggccaccgc
    21661 atcaacctga tcgacacccc cgggcacgtc gacttcgccg acgaggtgga gcgctcgctg
    21721 cgggtgctgg acggggcggt cgcggtgttc gacgccgtgg cgggtgtgga gccgcagagc
    21781 gagtccgtgt ggcggcaggc cgaccggcac ggcgtgccga ggatcgcgtt cgtcaacaaa
    21841 ctggaccgga cgggcgccga cctcgacacg gccgtggcgt cgatccggga acggctgcac
    21901 cccgtccccc tcgtcgtcca gctcccgatc ggcatcgagg acgccttcac cggcgtcgtc
    21961 gacctgctcc ggatgcgggc gctgacctgg ggcgacggcg ccgaggcggc cgtagaggga
    22021 accgtgcccg aggaactgcg cgaggaggcg ctgcgccgcc gccgactgct ggaggaagcg
    22081 gttgcggaac ggcatcccgc cgccctggag gagttctgcg accgggagac gctctcggcc
    22141 gagacgctcg ccgaggccct gcgcgacctg acccgcaccg gcgacggtgt ggtcgtgctg
    22201 tgcggctcgg cctaccgcaa ccgcggtatc gagccgttgc tcgacgccgt ggtcgcctat
    22261 ctgccgtcgc ccctggacgt gccggctgta cgcggcatgc acgagggtgt cgacgagcga
    22321 cggccggccg atcccgccgc acccttcgcc gccctcgcgt tcaaggtcaa cgccaccccc
    22381 accggcaggc tcacctacct gcgggtgtac tccggaacga tcgagaaggg agacacggta
    22441 tgggacgcga gcgcgggccg cggcgagcgc gtcggccgga tcctgcgggt ccaggccgac
    22501 cggcacgccc agctggagcg ggcggtcgcc ggggacatcg tggccgtgat cgggctgaag
    22561 gcggcccgcg ccggctcgac cctgtgcgcg ccggacgccc cgctggtcct cgaaccgccc
    22621 ggggtggccg accccgtcgt ctccgtggcg gtcgagccgc ggcgcggtac cgacgccgac
    22681 cggctggcct cggccctcgc ccggctggcc gaggaggacc cgtcgctcac ggtgcgcacc
    22741 gacgccgaga ccggccagac cgtgctctcg ggcatgggtg aactgcacct ggaggtcgcg
    22801 gtggagaaga tccgccgcgc cctcggactg gaggtcaacg tcggccggcc acgcgtcacc
    22861 taccgcgaga cggtgggccg cggcgtgtcc gcactggtct tccggcacgt caaacaggac
    22921 ggcggcgcgg gacagttcgc gcatgtcgtg ctcgatgtgg agcccttgga ggacgggttc
    22981 gacttccggt cggccgtggt cggcggacgg gtccctcagg agtacgtccg tgccgtagag
    23041 gccggctgcc gggacgccct cgccgagggt cccctcggcg ggcacgcggt gaccggcctg
    23101 cgggtcacgc tgaccgacgg ggcgacgcat gtgaaggact cctccgagat ggccttccgc
    23161 acggcgggcc gcctcggcct ccgcgaggcc ctgcgggctt gcacgatggt gttgctggaa
    23221 ccggtcgtgg aagtcacggt gaccgtcccc gaggacgccg tcggcggagt cctcggggac
    23281 ctcgccgccc ggcgcggccg ggtgaccggt tccgaggtgc gcggcggcgc ggccgtggtg
    23341 accgccaccg tgccgctcgc ggaactgttc ggctacgcca cccgactgcg cagccgcacc
    23401 cagggccggg gcaccttcac ggcccggccg acggggtacg ccccggcgcc ggcgctgacg
    23461 gcggcgccgt aggacccgta cgccccggag gggatcaccc tccggggcgt aggcgcgaaa
    23521 gcggtgtcga ggggggcgtc gaaggggtga ggagggcggc accggaggcc gcgcgtaggc
    23581 gggtccacgt cgaccaccac acccagaccc gcacgaccaa gggcaccgga cgccactacg
    23641 ccgacatcgt ccgcagacac cgggaggg
//
