LOCUS       NZ_CP099468            31463 bp    DNA     linear   CON 04-JUL-2024
DEFINITION  Streptomyces phaeoluteigriseus strain Qhu-M197 chromosome, complete
            genome.
ACCESSION   NZ_CP099468
VERSION     NZ_CP099468.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces phaeoluteigriseus
  ORGANISM  Streptomyces phaeoluteigriseus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1  (bases 1 to 9026270)
  AUTHORS   Zhang,B., Xiang,X. and Fan,J.
  TITLE     Complete genome sequence of soil microorganisms Streptomyces sp.
            Qhu-M197 isolated from Alpine meadows habitats on the Tibetan
            Plateau
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9026270)
  AUTHORS   Zhang,B., Xiang,X. and Fan,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2022) Faculty of Eco-Environmental Engineering,
            qinghaiuniversity, No. 251 Ningda Road, Chengbei District, Xining
            City, Qinghai Province 810000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Hifiasm v. v0.14; Circlator v. v1.5.5; Pilon v.
            v1.22
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 68.51291x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023923245.1-RS_2024_07_04
            Annotation Date                   :: 07/04/2024 06:06:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,100
            CDSs (total)                      :: 8,006
            Genes (coding)                    :: 7,707
            CDSs (with protein)               :: 7,707
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 299
            CDSs (without protein)            :: 299
            Pseudo Genes (ambiguous residues) :: 0 of 299
            Pseudo Genes (frameshifted)       :: 130 of 299
            Pseudo Genes (incomplete)         :: 241 of 299
            Pseudo Genes (internal stop)      :: 34 of 299
            Pseudo Genes (multiple problems)  :: 90 of 299
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:40:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2359387
            Orig. end                         :: 2390850
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP099468.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..31463
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="6"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..31463
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31463
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:17463]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..17463
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            149..397
                     /locus_tag="NFX46_RS10540"
                     /old_locus_tag="NFX46_10540"
     CDS             149..397
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983462.1"
                     /locus_tag="NFX46_RS10540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10540"
                     /product="hypothetical protein"
                     /protein_id="WP_073498401.1"
                     /transl_table=11
                     /translation="MRLRVEFTTEPFDLDEAPAHALVAREVVEAADLDAVDVGPFGNTV
                     EGGADAVLGAVDALLRRTLEAGATRISLQVNVLGEGE"
     gene            394..762
                     /locus_tag="NFX46_RS10545"
                     /old_locus_tag="NFX46_10545"
     CDS             394..762
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003993972.1"
                     /locus_tag="NFX46_RS10545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10545"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_252548153.1"
                     /transl_table=11
                     /translation="MTGSGQESFIAAVKPLVDAMGGELVPPDEAGPDDVVLSWEGADAV
                     AVRLPQLADSLDHILAAMERKKGKPLADLDRKAKQEVVRILEARGAFSVRHGVETVASA
                     LGVSRFTVYNYLNREKGS"
     misc_feature    809..822
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.52"
                     /tool="antismash"
     misc_feature    complement(809..823)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.33"
                     /tool="antismash"
     misc_feature    810..823
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.96"
                     /tool="antismash"
     misc_feature    complement(813..828)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.55"
                     /tool="antismash"
     gene            904..1422
                     /gene="uraD"
                     /locus_tag="NFX46_RS10550"
                     /old_locus_tag="NFX46_10550"
     CDS             904..1422
                     /EC_number="4.1.1.97"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="uraD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996704.1"
                     /locus_tag="NFX46_RS10550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10550"
                     /product="2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline
                     decarboxylase"
                     /protein_id="WP_252548154.1"
                     /transl_table=11
                     /translation="MTSTSPPPGLARFNALEESAALAALHEACASTTWAKHLLAARPCA
                     TADDLYAASDAATADLTAADLDEAMAGHPPIGRPRPGDPTSAREQRGMAGASEELKAQM
                     LELNLAYQERFGHVFLICATGRTGEQMRDAVRERLANAPEREREIVRVELGKINRIRLA
                     RLVENGVDE"
     gene            1563..1967
                     /gene="uraH"
                     /locus_tag="NFX46_RS10555"
                     /old_locus_tag="NFX46_10555"
     CDS             1563..1967
                     /EC_number="3.5.2.17"
                     /GO_function="GO:0033971 - hydroxyisourate hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006144 - purine nucleobase metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="uraH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656872.1"
                     /locus_tag="NFX46_RS10555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10555"
                     /product="hydroxyisourate hydrolase"
                     /protein_id="WP_073498406.1"
                     /transl_table=11
                     /translation="MSTSTTASVSTHILDTSVGRPAEGVAVHLSARAGRDADWQALGGS
                     ATDTDGRCKDLPALPEGTTHVRLDFAVEPYLEKTAKKQADAQQDAPANRDSGPGVFFPE
                     VAITFAVVPGEHYHVPLLLNPFGYSVYRGS"
     gene            1972..2901
                     /gene="pucL"
                     /locus_tag="NFX46_RS10560"
                     /old_locus_tag="NFX46_10560"
     CDS             1972..2901
                     /EC_number="1.7.3.3"
                     /GO_function="GO:0004846 - urate oxidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pucL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153181.1"
                     /locus_tag="NFX46_RS10560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10560"
                     /product="factor-independent urate hydroxylase"
                     /protein_id="WP_252548155.1"
                     /transl_table=11
                     /translation="MPTFLGQNQYGKAENRVVKITRDGATHHIKDLNVSVSLSGDMDEV
                     HYSGSNANVLPTDTTKNTVYAFAKEHGIESAEQFGIHLARHFVTSQEPIHRARIRIEEY
                     AWERIETSGAGARAGADEAKHSFVRQGQETRLTQITYDGESWEVVSGLKDLVVMNSTDS
                     EFWGYVKDKYTTLPEAYDRILATQVSARWRFNWTDDAREMPNWEESYEQTKKHLLQAFA
                     ETYSLSLQQTLFQMGSRIIDHRGEIDEVRFSLPNKHHFLVDLEPFGLKNDTADGAVYFA
                     ADRPYGLIEGTVLRDGCEARIPVDLSNL"
     gene            3122..4501
                     /locus_tag="NFX46_RS10565"
                     /old_locus_tag="NFX46_10565"
     CDS             3122..4501
                     /EC_number="3.5.4.32"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656870.1"
                     /locus_tag="NFX46_RS10565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10565"
                     /product="8-oxoguanine deaminase"
                     /protein_id="WP_073498410.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 6.6e-60, bitscore:
                     202.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAADRRIVIENCAIATVDAHDTEHASGYVVIAGHRIESVGAGPAP
                     AGLENVARRIDATGHLVTPGLVNTHHHFYQWITRGLATDHNLFDWLVALYPTWARIDEP
                     MVRAAAQGSLAMMARGGVTTAMDHHYVFPHGSGDLSGAIIGAARDMGVRFTLARGSMDR
                     SEKDGGLPPDFAVETLEGALAATEETVRQHHDASFDAMTQVAVAPCSPFSVSTELLRQG
                     AELARRLGVRLHTHGSETVEEEKFCHELFGMGPTDYFESTGWLGEDVWMAHCVHMNDSD
                     IDAFARTRTGVAHCPSSNARLAAGIARVPDMLAAGVPVGLGVDGTASNESGELHTELRN
                     ALLINRLGAHREAALNARQALRLGTFGGAQVLGRASQIGSLEPGKLADLVLWRMDTLAH
                     ASIADPVTALVLGAAAPVTASFVNGRQIVEDGRLLTADEDAIARATREEARRLARIAAQ
                     G"
     gene            4826..6253
                     /locus_tag="NFX46_RS10570"
                     /old_locus_tag="NFX46_10570"
     CDS             4826..6253
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996701.1"
                     /locus_tag="NFX46_RS10570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10570"
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="WP_289782048.1"
                     /transl_table=11
                     /translation="MSTQPPASTAEPAAPPIHPVDERLPALQMATSGLQHVAAMYAGVV
                     APPLIVGAAVGLTATELTFLTGACLFTAGLATFLQTLGIWKIGARLPFVNGVTFAGVAP
                     MTAIVASTEDKSDALPVIFGAVIVAGLLGFLAAPIFCKAVRFFPPVVTGTVITLIGVSL
                     LPVAFGWAQGPNPAGSDYGSATNLTLAGVTLLLVLLLRRFTRGFVKQIAVLLGLVAGTL
                     VAIPFGVTDFGPVAAADVVGFPTPFHFGAPQFQLAAILSMCVVMVVSMTESTADMLALG
                     EIVDRPADEKTIAAGLRADTLGSALSPVFNGFMCSAFAQNIGLVAMTRIRSRYVVASGG
                     AFLVLMGLCPMAASLIAVVPRPVLGGAGVVLFGSVAASGIQTLVRAGLEKDNNVLIVAV
                     SLAVGIIPITAPGFYHAFPETARIVLDSGISTGCVAAVLLNLVFNHLGRSADAQDVTHP
                     MEAGEEITGATRAPATP"
     gene            complement(6219..6821)
                     /locus_tag="NFX46_RS10575"
                     /old_locus_tag="NFX46_10575"
     CDS             complement(6219..6821)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125449.1"
                     /locus_tag="NFX46_RS10575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10575"
                     /product="3'-5' exoribonuclease"
                     /protein_id="WP_252548156.1"
                     /transl_table=11
                     /translation="MAVRRSRPSLYISVDIEADGPIPGPYSMLSLGAAVAGVQDADGFT
                     AGDPEARTFYRELRPVSDDFVPEALAVSGLDRERLRTEGLDPALALGQFTRWVREVSEG
                     AQPVMCGYPASYDWTFLYWYLIRFTGESPFGHSGCLDMKTLYAVKAGVPLRAVAKRSMP
                     AELLPRRRHTHHALDDAVEQAELFAHLMAWQGPGSPR"
     misc_feature    complement(6810..6825)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.37"
                     /tool="antismash"
     misc_feature    complement(7044..7058)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.09"
                     /tool="antismash"
     gene            <7138..7464
                     /locus_tag="NFX46_RS10580"
                     /old_locus_tag="NFX46_10580"
                     /pseudo=""
     CDS             <7138..7464
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656864.1"
                     /locus_tag="NFX46_RS10580"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10580"
                     /product="helix-turn-helix domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="RVSGKWSVQILVAAAHGPIRFTELERGIEGISRRMLTLTLRNLER
                     DGLVTRTVHPTVPPKVEYELTPVARELHETLLRLTGWAERNRVYIAESRAAYDNEHDRE
                     SAEA"
     gene            complement(7487..7909)
                     /locus_tag="NFX46_RS10585"
                     /old_locus_tag="NFX46_10585"
     CDS             complement(7487..7909)
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004981448.1"
                     /locus_tag="NFX46_RS10585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10585"
                     /product="acyl-CoA thioesterase"
                     /protein_id="WP_252548157.1"
                     /sec_met_domain="4HBT_2 (E-value: 7.4e-22, bitscore: 76.9,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEPFSVRVTVRGYETDVQGHLNQSVYINYAEHARWSLLQAAGIT
                     QAGLIGRGVGPVALETTIRYRRELLAGDEVDVTCAFEWGGGKTFRIEQIIRKTDGTVAA
                     ELSAVGGLLDLQARRMVADPQDHFKQLATDPGLFGL"
     misc_feature    complement(7899..7914)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.45"
                     /tool="antismash"
     gene            complement(7970..8665)
                     /locus_tag="NFX46_RS10590"
                     /old_locus_tag="NFX46_10590"
     CDS             complement(7970..8665)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675830.1"
                     /locus_tag="NFX46_RS10590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10590"
                     /product="hypothetical protein"
                     /protein_id="WP_252548158.1"
                     /transl_table=11
                     /translation="MTRPPTAAQRRVIDTADPVTGRLRGTESQLAALVERGLAFRHPRA
                     PHDHFLTPAGHRIREAEPEAGPAAAVDAPRAPTGVFTARVGGEEQPPDGGPSRMREVRS
                     AWQGLLELRRMTNPDGAVDRPCGWERTHLVQAAALALEAAGHRPAGPDAGGPDAGGPDA
                     GGPDAGGPASDGYRVRATPQPDAVAVRGPDDGTLGACAMTLEKAGWQAGEHTDPRSRTR
                     YLLASPRRV"
     gene            complement(8767..9366)
                     /locus_tag="NFX46_RS10595"
                     /old_locus_tag="NFX46_10595"
     CDS             complement(8767..9366)
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972709.1"
                     /locus_tag="NFX46_RS10595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10595"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_252548159.1"
                     /transl_table=11
                     /translation="MGDLFLVRHGETAWSRSGRHTGLTDVPLTEHGREEARRLVPLIRS
                     HRIGAAFSSPLQRARETAELIGLHEVRVDADLQEWDYGGYEGVTTVEIQRERPGWFLFT
                     DGVTPGPPEHPGETPEQVGERADRMLAKVDAALANTEGCVVLVAHGHFLRVLTARRLGL
                     PPSAGALFQLATGTLGRLGTEHGRHVIAGWNIRPGA"
     misc_feature    complement(9377..9392)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.34"
                     /tool="antismash"
     gene            complement(9930..11138)
                     /locus_tag="NFX46_RS10600"
                     /old_locus_tag="NFX46_10600"
     CDS             complement(9930..11138)
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (33-393). E-value:
                     6.1e-55. Score: 178.7. Matches aSDomain:
                     nrpspksdomains_NFX46_RS10600_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007390030.1"
                     /locus_tag="NFX46_RS10600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10600"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_252548160.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 7.7e-53, bitscore:
                     178.8, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 6.5e-06,
                     bitscore: 24.5, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 1.9e-05, bitscore:
                     22.6, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFRQSNKLSEVCYEIRGPVIEHANALEAAGHSVLRLNTGNPALF
                     GFEAPEEILQDMIRMLPRAHGYTDSRGVLTARRAVAQRYQDRGLEVDVDDVWLGNGVSE
                     LVSMAVQALIEDGDEILIPAPDFPLWTAVTTLAGGKAVHYLCDEQADWYPDLDDMASKI
                     TDRTKAVVIINPNNPTGAVYPKEIIEGILDLARRHGLMVFADEIYDQILYDDAVHHSAA
                     ALAPDLVVLTFCGLSKTYRVAGFRSGWLVVTGPRQHARDYLEGLTMLASMRLCANAPAQ
                     YAIQAALGGRQSIRELTGPGGRLRDQRDIAWEKLNEIPGVSCVKPKGALYAFPRIDPKV
                     HPLHDDEKFVLDLLLREKIQVVQGTGFNWPTPDHFRILTLPHAEDLEAAIGRIGRFLSG
                     YRQ"
     aSDomain        complement(9960..11039)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NFX46_RS10600_Aminotran_1_2.1"
                     /evalue="6.10E-55"
                     /label="NFX46_RS10600_Aminotran_1_2.1"
                     /locus_tag="NFX46_RS10600"
                     /protein_end="393"
                     /protein_start="33"
                     /score="178.7"
                     /tool="antismash"
                     /translation="VLRLNTGNPALFGFEAPEEILQDMIRMLPRAHGYTDSRGVLTARR
                     AVAQRYQDRGLEVDVDDVWLGNGVSELVSMAVQALIEDGDEILIPAPDFPLWTAVTTLA
                     GGKAVHYLCDEQADWYPDLDDMASKITDRTKAVVIINPNNPTGAVYPKEIIEGILDLAR
                     RHGLMVFADEIYDQILYDDAVHHSAAALAPDLVVLTFCGLSKTYRVAGFRSGWLVVTGP
                     RQHARDYLEGLTMLASMRLCANAPAQYAIQAALGGRQSIRELTGPGGRLRDQRDIAWEK
                     LNEIPGVSCVKPKGALYAFPRIDPKVHPLHDDEKFVLDLLLREKIQVVQGTGFNWPTPD
                     HFRILTLPHAEDLEAAIGRI"
     gene            11220..11846
                     /locus_tag="NFX46_RS10605"
                     /old_locus_tag="NFX46_10605"
     CDS             11220..11846
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071191.1"
                     /locus_tag="NFX46_RS10605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10605"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_252548161.1"
                     /transl_table=11
                     /translation="MPPRRSYDQYCSAARALDTVGDRWTLLIVRELLAGPRRYTDLHAD
                     LPGVSTDVLASRLKDMERDGLATRRRLPPPGAANVYELTGRGRALLPVLQALGAWGQAE
                     LGERGPTDAIRAHWFALPLLRALEGEGLVEVRLDEGHFHLFVGTDEGPVYGHGAAPGEP
                     DALLVMDTATCTAVAQGVLSLLDAVRAGRVEVSGEGTLAKGLRQA"
     gene            complement(11889..12695)
                     /locus_tag="NFX46_RS10610"
                     /old_locus_tag="NFX46_10610"
     CDS             complement(11889..12695)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071192.1"
                     /locus_tag="NFX46_RS10610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10610"
                     /product="hypothetical protein"
                     /protein_id="WP_252548162.1"
                     /transl_table=11
                     /translation="MRITRVLSTTLLALGLAATPAAADSTPSASPSEDGSAPTTAGTSF
                     RTATEVDQGRTATASGSAGDYLYWSFPADAGQRPTVTAKVKLPEEHAGQTWQVDVYDGL
                     RRRQSCQYGAQTRTAAPGTASLELACVLRTVRAWSEPWADDPLPGTYYVRLTVVGLKTA
                     DLGLPVGAELRVDSKDIGGSAAVDGSLAEPLVPGVAVKSSAEDEDDPSASAVLSSIEPD
                     DGWSSGWWSDRWVWTGIGGVLAALAGIGGYALTRGPGRPRNVPPGV"
     gene            complement(12695..13957)
                     /locus_tag="NFX46_RS10615"
                     /old_locus_tag="NFX46_10615"
     CDS             complement(12695..13957)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385720.1"
                     /locus_tag="NFX46_RS10615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10615"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_252548163.1"
                     /transl_table=11
                     /translation="MIRTQRLAAGLCALLAALTAGLAFPAGAVADGTTANAPKVNLVLD
                     VSGSMRAKDIDGGSRMAAAKQAFNEVLDATPEEVRLGIRTLGANYPGDDQKTGCKDTAQ
                     LYPVGPLDRTEAKAAVATLTPTGWTPIGPALLKAAEDLDGGTGSKRIVLISDGEDTCAP
                     LDPCEVAREIAAKGIGLTIDTLGLVPNVKMRQQLSCIAEATGGTYTSVEHTDELTDKVN
                     QLVDRAADPVVTPVATRGADSCAKAPTLKSGLYTDREEFGQERWYRVDLDPGKELRASV
                     SVSADRAMNPDYGLLVRAVTVHGREIVRGEAAGNGRTDVISTGLRYPKAESDDDEAPAE
                     TVCVQVTNSYSAAAGVKTTPGMPLELTVDVVDGPSQASDVASFGLGRGWWLLGALVLAG
                     FLAGVLWGWLSRWRVAVWRTN"
     gene            complement(14001..15527)
                     /locus_tag="NFX46_RS10620"
                     /old_locus_tag="NFX46_10620"
     CDS             complement(14001..15527)
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996683.1"
                     /locus_tag="NFX46_RS10620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10620"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_252548164.1"
                     /sec_met_domain="IucA_IucC (E-value: 5.9e-32, bitscore:
                     110.0, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRPPTAEAELAADLAAVRPALAARFAAELSGARAAVLTRLWRAL
                     AHEPLPWVVRRAAARDGLTLHLADGRRLHGPHADPYATAAYVTAVDLAGTAFDDPARLM
                     TDLAVPYGGGLAGELAHSTASLALSRAGQQPGEPGAGDVEGWPAHDWEWEQRVVDGHPY
                     HPNCRSRPGFSVAEQLAYGPEHRPPAVRLGLLPVPADECLVSGGWPAELRDGRRLLIPV
                     HPWQAAHVLKRSCVEGLAAHPLMSLRTLAVPDGPHVKTALSARLTSSVRDISVGSVAAS
                     SALSAFAESLAERTDGLLHMTRSLGAVTADSPDLAAVLRESPAVYAGPGEHVVPVAALA
                     TTELTSSPAWLADFARLALTVGLRLLEQGVALEAHGQNLLVVLSASGAPVRLVYRDLAD
                     IRVSPARLARHGLAAPELPARILTDDVTALRGKLFGSLVAGALAATAGSGEALGTALAA
                     AVPEVPDTGDLRALRGEPVPVKALTLMRLSPGGSGDRWARLPNPLVTRAF"
     gene            16015..17463
                     /locus_tag="NFX46_RS10625"
                     /old_locus_tag="NFX46_10625"
     CDS             16015..17463
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036601.1"
                     /locus_tag="NFX46_RS10625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10625"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_289782132.1"
                     /sec_met_domain="IucA_IucC (E-value: 1.2e-42, bitscore:
                     145.0, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEQQVHEPEVAERQMAEPRSRRGARQVHRLPSGRLLRVRGARRP
                     AEPEVRADGAWHRLDHRGLVDLVATELRHHTGLTNPELPAEMLDSRDAVAALLAARARA
                     TPPEDPYLRSEQSLLTGHPHHPAPKTRGGGPPGGWLPYAPEAYARFPLVLLGLREDTVV
                     EDGDTAALDALGEAPPGYRLLPAHPWQLDLARTALAPAFADGRLVRLGTTPFDTWPTAA
                     VRTLYAPGPDLFLKFSLDVRITNDIRRLWRHDLLRLRRTDAAATRALAAVGGPAAWLSD
                     RGYRTAGFAFEELAVMVRDGLHAHVTPGATPLLAAGLVEGFEGSPLAGTADPAHWWEAY
                     LAAVVPPALAAFADHGVVLEAHLQNTLVAVDSAGRPVQALFRDAEGVKLLPETERAAGW
                     ERLVYCLVVNHLTEVAAALADHHHGLDPWPAARRELARHDLPEVHALLAAPTLPGKTNL
                     LLRWTGADGADARYLPLPNPLAGS"
     gene            17484..18398
                     /locus_tag="NFX46_RS10630"
                     /old_locus_tag="NFX46_10630"
     CDS             17484..18398
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823965.1"
                     /locus_tag="NFX46_RS10630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10630"
                     /product="HipA family kinase"
                     /protein_id="WP_252548166.1"
                     /transl_table=11
                     /translation="MLRDVTAVRYVTPLRSGGSVPAVVEADDLGTYVVKFTGSAQGRKA
                     LVAEVIVGELARALGLRFPELVLVHFDPAIADGEPHQEVRDLHAASHGVNLGMDHLPGA
                     RDFTPDIAEVFPVDPLEAGRIVWLDALTVNVDRTVHSSNLMVWPTLGTVPPRLWLIDHG
                     AALVFHHRWDGSDPAKRYDFRHHALGRYAPDVRAADAELAPRVTEELLRAIVAQVPDAW
                     LLDEPAFTSADEARTAYVNHLHARVRASAAWLPTNFPTRDELAAEEARRAAKTRQGRPD
                     WLKRVPDLHGKPAAEQDWSVHLG"
     gene            18395..18697
                     /locus_tag="NFX46_RS10635"
                     /old_locus_tag="NFX46_10635"
     CDS             18395..18697
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125480.1"
                     /locus_tag="NFX46_RS10635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10635"
                     /product="Rdx family protein"
                     /protein_id="WP_252548167.1"
                     /transl_table=11
                     /translation="MTDTRLDGSGPRRVEIEYCTQCRWLPRAAWLAQELLTTFEGELTE
                     LALRPGKGGVFVVRVNDEVVWDRREQGFPEPTAVKRLVRDRVAPGKSLGHSDKPE"
     gene            complement(18711..20342)
                     /gene="aceB"
                     /locus_tag="NFX46_RS10640"
                     /old_locus_tag="NFX46_10640"
     CDS             complement(18711..20342)
                     /EC_number="2.3.3.9"
                     /GO_function="GO:0004474 - malate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006097 - glyoxylate cycle [Evidence IEA]"
                     /codon_start=1
                     /gene="aceB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133434.1"
                     /locus_tag="NFX46_RS10640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10640"
                     /product="malate synthase A"
                     /protein_id="WP_252548168.1"
                     /transl_table=11
                     /translation="MSASVPSPAAVVDAEPLPRQEEVLTDAALAFVAELHRRFTPRRDE
                     LLARRAERRAEIARTSTLDFLPETAAIRADDSWRVAPAPAALDDRRVEITGPTDRKMTI
                     NALNSGARVWLADFEDASAPTWENVVVGQLNLIDAYGGNIDFTDPGSGKSYALRPAEEL
                     ATVVMRPRGWHLDERHLQVDGRAVPGALVDFGLYFFHNAQRLLDLGKGPYFYLPKTESH
                     LEARLWNDVFVFAQDQVGVPQGSVRATVLIETITAAYEMEEILYELRDHASGLNAGRWD
                     YLFSIVKNFRDGGARFVLPDRNAVTMTAPFMRAYTELLVRTCHKRGAHAIGGMAAFIPS
                     RRDPEVNRVAFEKVRADKDREAADGFDGSWVAHPDLVPIAMESFDRVLGDRPHQKDRLR
                     EDVDVKAADLLAVDSLEARPTYAGLVNAVQVGIRYIEAWLRGLGAVAIFNLMEDAATAE
                     ISRSQIWQWINAGVEVDRDGTTVRVTPELAREVAAAELAAVRSEIGEEAFAAGHWQQAH
                     DLLLTVALDEDYADFLTLPAYEQLTG"
     misc_feature    20442..20458
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.9"
                     /tool="antismash"
     gene            complement(20530..21129)
                     /locus_tag="NFX46_RS10645"
                     /old_locus_tag="NFX46_10645"
     CDS             complement(20530..21129)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385730.1"
                     /locus_tag="NFX46_RS10645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10645"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_252548169.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.1e-35, bitscore:
                     122.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHTEDQVAGLLLAAGGGRRLGGRPKALLTHRGRPLVEHAVEALR
                     AAGCTRVHVVLGAAADAVRERARLDGCVPVVNPEWERGMGGSLRAGLDSLAGTGARAAL
                     VSLVDQPGIGGRALARVRAAYEDEESLASAAYDGRRGHPVLLGAAHWAGVTATATGDRG
                     ARDYLKAHEEEIRLVECGDVARPYDIDTVDDLAHLE"
     misc_feature    21177..21191
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.16"
                     /tool="antismash"
     gene            21334..21621
                     /locus_tag="NFX46_RS10650"
                     /old_locus_tag="NFX46_10650"
     CDS             21334..21621
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482211.1"
                     /locus_tag="NFX46_RS10650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10650"
                     /product="DUF5955 family protein"
                     /protein_id="WP_252556320.1"
                     /transl_table=11
                     /translation="MTGSDEDPRVAELRTAVSRLRRELAAHPAEFPDRGIAEDELAALA
                     AMAAHGIPEIPRLRRSLLLIAGAIGSVSALARGVSDVRSAVELFGESPQR"
     gene            complement(21679..22479)
                     /locus_tag="NFX46_RS10655"
                     /old_locus_tag="NFX46_10655"
     CDS             complement(21679..22479)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019521861.1"
                     /locus_tag="NFX46_RS10655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10655"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_252548170.1"
                     /transl_table=11
                     /translation="MPTSSASTTDSAKSGSGGVQSLERAFDLLERMADAGGEVGLSELS
                     ASSGLPLPTIHRLMRTLVACGYVRQQSNRRYALGPRLIRLGESSARLLGTWARPYLARL
                     VEETGETANMALLDGDEIVYVAQVPSKHSMRMFTEVGRRVLPHSTGVGKALLAGFPDTE
                     VRALLARTGMPAATDRTITTPEGFLAALDEVREAGYAVDDNEQEIGVRCLAVPVPDSPT
                     AAAISISGPAGRVTESATGKIVPVLQQVALELSEVLSNPGGTSV"
     misc_feature    complement(22484..22495)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(22572..22585)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.72"
                     /tool="antismash"
     gene            22785..24122
                     /gene="allB"
                     /locus_tag="NFX46_RS10660"
                     /old_locus_tag="NFX46_10660"
     CDS             22785..24122
                     /EC_number="3.5.2.5"
                     /GO_function="GO:0004038 - allantoinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0050897 - cobalt ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="allB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996674.1"
                     /locus_tag="NFX46_RS10660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10660"
                     /product="allantoinase AllB"
                     /protein_id="WP_252548172.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.9e-23, bitscore:
                     81.1, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDAELVLRSTRVITPEGTRAASVAVSAGTITAVLPYDAAVPSGA
                     RLEDLGDDVLLPGLVDTHVHVNDPGRTEWEGFWTATRAAAAGGITTLVDMPLNSLPPTT
                     TADHLRTKRRVAADKAHIDVGFWGGALPDNVKDLRPLHEAGVFGFKAFLSPSGVDEFPH
                     LDQDHLARSLAEIAGFDGLLIVHAEDPHHLESAPQRGGPKYADFLASRPRDAEDTAVAS
                     VIAQARRLHARVHVLHLSSSDALPLIAAAKAEGVRVTAETCPHYLTLTAEEVPDGASEF
                     KCCPPIREAANQDLLWQALADGTIDCVVTDHSPSTADLKTGDFATAWGGISGLQLSLAA
                     VWTEARARGHGLEDVVRWMSTRTAALVGLDRKGAIEAGRDADFAVLAPDETFTVDPAAL
                     QHRNRVTAYAGKTLHGVVKSTWLRGERIVADGEFTSPSGRLLTRAH"
     gene            24178..25308
                     /gene="alc"
                     /locus_tag="NFX46_RS10665"
                     /old_locus_tag="NFX46_10665"
     CDS             24178..25308
                     /EC_number="3.5.3.4"
                     /GO_function="GO:0004037 - allantoicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="alc"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972679.1"
                     /locus_tag="NFX46_RS10665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10665"
                     /product="allantoicase"
                     /protein_id="WP_252548174.1"
                     /transl_table=11
                     /translation="MTAQHQSSLAGFTGDANPYGGGDPYADYRTADFPFTSYANLADRQ
                     LGAAVIAANDEFFAQRENLLLPGPAEFDPEHFGHKGKIMDGWETRRRRGVSADHPWPTA
                     DDHDWALVRLGAPGVIRGVVVDTAHFRGNYPQAVSVEGTSVPGSPSPEALLGDDVKWTT
                     LVPRTPVGGHAANGFAVSVEQRFTHLRVNQHPDGGIARLRVYGEVVPDPEWLAVLGTFD
                     VVALENGGLAEDASDLFYSPAGNTIQPGRSRKMDDGWETRRRRDRGNDWIRYRLAAQAE
                     IRALEIDTAYLKGNSAGWAAVSVRDGEEGEWREILPRTRLQPDTNHRFALAAPAVGTHA
                     RVDIYPDGGISRLRLIGSLTDAGAGALRARHQELGG"
     gene            complement(25992..26738)
                     /locus_tag="NFX46_RS10670"
                     /old_locus_tag="NFX46_10670"
     CDS             complement(25992..26738)
                     /NRPS_PKS="Domain: PKS_KR (11-169). E-value: 1e-11. Score:
                     37.0. Matches aSDomain:
                     nrpspksdomains_NFX46_RS10670_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125487.1"
                     /locus_tag="NFX46_RS10670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10670"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_252548176.1"
                     /sec_met_domain="adh_short (E-value: 3.4e-33, bitscore:
                     114.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSDKTLNGKVALVTGGSRGIGAATAVRLAREGADVALTYVNGK
                     EAAEDVVRAVEALGRRAVALRADSADAAEAAGAVGAAADALGGLDVLVNNAGIGVLGPL
                     EDLSLADVDRVLAVNVRGVFLTSQAAAGRMGAGGRIITVGSCMVQRVPGPGGTLYALSK
                     SALVGLTKGLARDLGPRGITASLVHPGPIDTDMNPADGPYAAGQAALTALGRFGTGDEV
                     ASMVAYLAGATYVTGAEYAVDGGHAA"
     aSDomain        complement(26232..26705)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_NFX46_RS10670_PKS_KR.1"
                     /evalue="1.00E-11"
                     /label="NFX46_RS10670_PKS_KR.1"
                     /locus_tag="NFX46_RS10670"
                     /protein_end="169"
                     /protein_start="11"
                     /score="37.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALVTGGSRGIGAATAVRLAREGADVALTYVNGKEAAEDVVRAVE
                     ALGRRAVALRADSADAAEAAGAVGAAADALGGLDVLVNNAGIGVLGPLEDLSLADVDRV
                     LAVNVRGVFLTSQAAAGRMGAGGRIITVGSCMVQRVPGPGGTLYALSKSALVGL"
     CDS_motif       complement(26634..26699)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_NFX46_RS10670_0001"
                     /evalue="1.70E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="NFX46_RS10670"
                     /protein_end="35"
                     /protein_start="13"
                     /score="17.5"
                     /tool="antismash"
                     /translation="LVTGGSRGIGAATAVRLAREGA"
     gene            26879..27508
                     /locus_tag="NFX46_RS10675"
                     /old_locus_tag="NFX46_10675"
     CDS             26879..27508
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494503.1"
                     /locus_tag="NFX46_RS10675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10675"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_252548178.1"
                     /transl_table=11
                     /translation="MGKLVLTGFVTLDGVHQAPGGPHEDPRGGFGQGGWSVPYGDEDFG
                     RFVTEVFDRAGAFLLGRRTYDIFASYWPKVTDPADPVASRLNSLPKYVAGSAPLADPVW
                     PGATAVHGDLVKQVTTLKERTEGELQVHGSGALAASLLALDLVDTLHLLTFPVVLGAGR
                     RLFAEGARPTAFRHTGGRVTAAGVSIQTYDLDGRPSYGTYELPDGV"
     gene            complement(27554..28198)
                     /locus_tag="NFX46_RS10680"
                     /old_locus_tag="NFX46_10680"
     CDS             complement(27554..28198)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014818415.1"
                     /locus_tag="NFX46_RS10680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10680"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_252548180.1"
                     /transl_table=11
                     /translation="MAQLLRVQNFNVSSDGIGAGEDQSFERPFGHVDPGRLFAWAGATA
                     SWPMRTDPGGSRGLDDHFTRDYARNIGAEIMGRNKFGPLRGPWQDDEWRGWWGDAPPFH
                     TPVFVMTHHERPSFTLSDTTFHFVGGDPAAVLARAREAAQGKDVRLGGGVTTVRQFLDA
                     GLVDTLHVAVSPVELGSGLKLWDSPDELLDRYHLEVVPSPSGVTHHLFWRK"
     gene            28364..28759
                     /locus_tag="NFX46_RS10685"
                     /old_locus_tag="NFX46_10685"
     CDS             28364..28759
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004521 - RNA endonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018554703.1"
                     /locus_tag="NFX46_RS10685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10685"
                     /product="ribonuclease domain-containing protein"
                     /protein_id="WP_252548182.1"
                     /transl_table=11
                     /translation="MRFPPRITRIGGAAALLSALLVGGTVSAGSANAAATAVGSICYSD
                     LPSQAYTTLRLIDQGGPFPYSQDGSVFQNREGILPSKSSGYYHEYTVKTPGSSTRGARR
                     IVTGQQTEEDYYTADHYASFDLVDHDC"
     gene            complement(28841..29041)
                     /locus_tag="NFX46_RS10690"
                     /old_locus_tag="NFX46_10690"
     CDS             complement(28841..29041)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996668.1"
                     /locus_tag="NFX46_RS10690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10690"
                     /product="hypothetical protein"
                     /protein_id="WP_252548184.1"
                     /transl_table=11
                     /translation="MKQLLEVLGFIALVQGVAGLVHEFTDLDWGLVQRLGVLDGYEVYA
                     SVALLVLAFALFAAAESRKPG"
     gene            29242..30510
                     /locus_tag="NFX46_RS10695"
                     /old_locus_tag="NFX46_10695"
     CDS             29242..30510
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983430.1"
                     /locus_tag="NFX46_RS10695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10695"
                     /product="histidine kinase"
                     /protein_id="WP_252548186.1"
                     /transl_table=11
                     /translation="MRGDDRPTPAPEAAIFPTRRWLLPSAVAAEPDPDAGRPGRAPRRT
                     ARDWLVDFTCFVLAVVLGLVVADTLTEQENLPHSLVVADQLLGALACAAVWLRRRWPFG
                     LAAATIPLAFLSTTSAGACTIALFTLAVHRPFRYVAWVGGLQLAVIPLLVWARPDPDLE
                     YGPAVVWTVLITVAVIGWGMLVRSRRQLMLSLRDRARRAETEARLRAEQAQRLAREAIA
                     REMHDVLAHRLTLLSVHAGALEFRPDAPREEIVRAAGVIRESAHEALQDLREIIGVLRA
                     GEHDDAGRPQPTLAALDALVAESREAGMKVTLDQRVSDPGAVPASVGRTAYRITQECLT
                     NTRKHAPGAEAAVVVAGAPGEGLTVTVRNPAPEGDVPPVPGSGQGLIGLTERAALTGGR
                     LEHGPREDGGFEVRAWLPWPLTT"
     gene            30615..31283
                     /locus_tag="NFX46_RS10700"
                     /old_locus_tag="NFX46_10700"
     CDS             30615..31283
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010038949.1"
                     /locus_tag="NFX46_RS10700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_10700"
                     /product="response regulator transcription factor"
                     /protein_id="WP_252548188.1"
                     /transl_table=11
                     /translation="MTAIRLLLVDDDPLVRAGLSLMMGGAEDIEIVGEAADGGEVEALV
                     ERTRPDVVLMDIRMPSVDGLTATRRLRAREDAPQVVVLTTFHADEHVLRALRAGAAGFV
                     LKDTPPARIVEAVRRVAAGDPVLSPTVTRQLMAHVAGTAADDRRARARARIAVLGERER
                     EVTVAVGRGLSNAEIAAALFMSVATVKTHVSRVLAKLDLNNRVQIALLAYDAGLLEDED
                     "
ORIGIN
        1 tgaccgaccc gccggtcggt taaggtcggg gtccggagcc gccccgatgg tccgttcgtg
       61 cgccgagggg tcgcgtccgg accgccctcc tcggtgaggt caggtgtgaa acgcgcaggt
      121 caggcaggtc agagaggtat ggggcgcgat gcgactgagg gttgagttca ccaccgagcc
      181 cttcgatctc gacgaggcac ccgcgcacgc gctggtcgcc cgcgaggtcg tcgaggccgc
      241 cgacctggac gcggtggacg tgggcccctt cggcaacacc gtggagggtg gcgccgacgc
      301 cgtcctgggt gcggtcgacg ccctgctccg caggaccctg gaagccggtg ccacccggat
      361 ctccctccag gtcaacgtcc tcggggaggg cgaatgaccg ggtcggggca ggagtccttc
      421 atcgccgccg tgaaacccct ggtcgacgcc atgggtgggg aactggtccc gccggacgag
      481 gccggtcccg acgacgtcgt gttgtcctgg gagggcgccg acgccgtcgc cgtacggctg
      541 ccgcagctcg ccgactccct cgatcacatc ctggccgcga tggagcggaa gaagggcaag
      601 cccctcgccg acctggaccg caaggccaag caggaggtcg tgcggatact ggaggcgcgc
      661 ggtgcgttct cggtgcggca cggcgtggag accgtggcga gcgctctcgg agtgagccgt
      721 ttcaccgttt acaactacct caaccgcgag aaggggagct gagcgggcgt ccgtgacccc
      781 gcggggggct ccgggtttcg ttacccggaa ttttcaacaa agtgttgact ggttgtcgtg
      841 ggtaggcgtt agctagccgc agtccgatca gcacgaaggc cgttcacggc cacggaggct
      901 cccgtgacgt cgacttcccc gcccccggga ctggcccggt tcaacgccct cgaagagtcc
      961 gcggccctcg ccgcactcca cgaggcctgc gcctccacca cctgggcgaa gcacctcctc
     1021 gcggcccgcc cctgcgccac cgccgacgac ctctacgccg ccagtgacgc cgccacggcc
     1081 gacctgaccg ccgcggacct ggacgaggcg atggccggtc acccgcccat cggccgtccc
     1141 aggccgggtg acccgacctc cgcccgcgag cagcgcggca tggccggggc ctccgaggag
     1201 ctgaaggcac agatgctcga actgaacctg gcctatcagg agaggttcgg ccacgtcttc
     1261 ctgatctgcg ccaccggccg gaccggcgag cagatgcgcg acgccgtacg ggaacggctc
     1321 gcgaacgcgc cggaacggga acgggagatc gtccgcgtcg agctgggcaa gatcaaccgc
     1381 atccgcctgg cgcgactcgt cgaaaacggt gtcgacgaat gagccggact cggccgacca
     1441 ccaggtgacc gagggcgacc gagcgactga accgaccgag ggacgaccga ggacgatcga
     1501 gccgcccgag ccgcccgagc cgcccgaacc gaccgagccg accgaagagg acgcccgtaa
     1561 ccatgagcac cagcaccacc gcctccgtgt ccacgcacat cctggacacc agcgtcggcc
     1621 gccccgccga gggtgtcgcc gtccacctct cggcccgcgc cggccgggac gcggactggc
     1681 aggcgctcgg cggttccgcg accgacacgg acggccggtg caaggacctg ccggccctgc
     1741 cggagggaac cacccacgta cggctcgact tcgccgtgga gccgtatctc gagaagaccg
     1801 cgaagaaaca agccgatgcg cagcaggacg cccccgcgaa tcgggacagc ggaccgggcg
     1861 tgttcttccc ggaggtggcg atcacgttcg ccgtcgtgcc gggcgagcac taccacgtac
     1921 cgctgctgct caacccgttc ggctactccg tttaccgagg gagctagcta gatgcccacc
     1981 tttctgggac agaaccagta cggcaaggcc gagaaccgag tcgtcaagat cacgcgggac
     2041 ggcgccaccc accacatcaa ggacctcaac gtctcggtgt cgctgagcgg tgacatggac
     2101 gaggtccact actccggctc gaacgccaac gtcctgccga ccgacaccac gaagaacacg
     2161 gtgtacgcgt tcgccaagga gcacggcatc gagtccgccg agcagttcgg catccacctc
     2221 gcccgccact tcgtcacctc gcaggagccc atccaccggg cccgcatccg catcgaggag
     2281 tacgcctggg agcggatcga gacctccggc gccggcgcga gggcgggcgc cgacgaggcg
     2341 aagcactcct tcgtccgcca gggccaggag acccggctaa cccagatcac ctacgacggt
     2401 gagtcctggg aggtcgtctc cggactgaag gacctggtcg tgatgaactc gacggactcc
     2461 gagttctggg gatacgtcaa ggacaagtac acgacgctcc ccgaggccta cgaccgcatc
     2521 ctcgccaccc aggtgtccgc ccgctggcgg ttcaactgga ccgatgacgc gcgggagatg
     2581 cccaactggg aggagtccta cgagcagacg aagaagcacc tgctccaggc cttcgccgag
     2641 acgtactccc tctcgctcca gcagacgctg ttccagatgg gttcgcggat catcgaccac
     2701 cgcggcgaga tcgacgaggt ccgtttctcc cttccgaaca agcaccactt cctcgtggac
     2761 ctggagccgt tcgggctgaa gaacgacacc gccgacggag ccgtgtactt cgcggccgac
     2821 cggccctacg gcctgatcga ggggaccgtg ctgcgggacg gctgtgaggc ccgcataccg
     2881 gtggacctca gcaacctctg acgtatccga ttcaccgcgg cacccgtgcc cgggggaacg
     2941 ggaacggacg gcgaacggga acggacggcg aacgggaacg gatggggaaa cggtcgctac
     3001 gcccctttcc gcacccgcac ccgcacccct ccccgcaccc ccacccgtcc cgcccggtca
     3061 cggcactcaa agctcccggg gtcctgccgt gccctctccc tctcagcgca aaggacgaac
     3121 catggcagca gaccggcgca tcgtcatcga gaactgtgcg atcgcgaccg tcgacgccca
     3181 cgacaccgag catgcgagcg ggtacgtcgt catcgccggc catcgcatcg agtcggtcgg
     3241 cgcgggcccg gccccggcgg gtctggagaa cgtcgcccgc cgcatcgacg ccaccgggca
     3301 cctcgtcact cccggtctgg tcaacaccca ccaccacttc taccagtgga tcacccgcgg
     3361 cctggccacg gaccacaacc tgttcgactg gctcgtcgcg ctctacccca cctgggcccg
     3421 catcgacgag ccgatggtcc gcgccgccgc gcagggctcc ctcgcgatga tggcgcgcgg
     3481 cggcgtcacc accgccatgg accaccacta cgtcttcccg cacggttccg gcgacctgtc
     3541 cggcgcgatc atcggggccg cccgcgacat gggcgtgcgc ttcaccctgg cccggggctc
     3601 catggaccgc agcgagaagg acggcggact gcccccggac ttcgccgtcg agaccctgga
     3661 gggtgccctc gccgccaccg aggagaccgt acggcagcac cacgacgcct ccttcgacgc
     3721 gatgacccag gtcgccgtcg ccccctgctc gcccttctcc gtcagcaccg aactgctccg
     3781 ccagggagct gagttggccc gccggctcgg cgtacgcctg cacacgcacg gctcggagac
     3841 ggtcgaggag gagaagttct gccacgagct gttcggcatg ggcccgaccg actacttcga
     3901 gtccacgggc tggctgggcg aggacgtgtg gatggcgcac tgcgtccaca tgaacgactc
     3961 cgacatcgac gccttcgccc gcacgaggac cggtgtcgca cactgcccgt cctccaacgc
     4021 ccggctcgcg gcggggatcg cgcgggtgcc ggacatgctc gcggccggtg tcccggtcgg
     4081 cctcggcgtc gacggcacgg cgtccaacga gtccggcgaa ctccacaccg agctgcgcaa
     4141 cgccctcctg atcaaccgcc tcggcgctca ccgcgaggcc gccctgaacg cccgccaggc
     4201 gctgcgcctc ggcacgttcg gcggcgccca ggtcctcggc cgggcgagcc agatcggctc
     4261 gctggagccg ggcaagctcg ccgacctggt gctgtggagg atggacaccc tcgcccacgc
     4321 ctccatcgcc gacccggtga ccgcgctggt cctcggcgcg gcggccccgg tcaccgcctc
     4381 tttcgtgaac ggccgtcaga tcgtcgagga cggccggctg ctcaccgccg acgaggacgc
     4441 gatcgcccgc gcgacccgcg aagaggcccg gcgcctggcg cggatcgccg cccagggctg
     4501 acccgttgag actccggccg ggagggacgg ctcccggccg gtggccgtgg acccgagagg
     4561 gtccacggcg gccgtgaccg gggcgcgtgc ggacgcgcgc gccccggaac ggtcacccct
     4621 gccgttgccc gcggtctccc accgcttccc gcagtcgagc cgctccgctg tttccagccg
     4681 ttcccaccgt ttcgagcgtt ccccgcggtc cccgcgtttc gagcgttccc agcgttccca
     4741 gcgttccccg gtcccgcacg accgtgcacc acctccatga aacccacgcc agagctgccg
     4801 tgtaaccgac cggaggagag ccgccgtgtc cacgcaacca cccgcctcga cagccgaacc
     4861 agccgccccg cccatccacc ccgtggacga gagactgccc gccctgcaaa tggcgacaag
     4921 cggtctccag cacgttgccg ccatgtacgc cggagtcgtc gccccgccgc tgatcgtcgg
     4981 cgcggccgtc ggtctgaccg ccaccgaact caccttcctc accggcgcct gcctcttcac
     5041 cgcgggcctg gccaccttcc tccagacact gggcatctgg aagatcggcg cccgcctgcc
     5101 cttcgtcaac ggcgtcacct tcgccggtgt cgcccccatg acggcgatcg tcgcctccac
     5161 cgaggacaag tccgacgcgc tgcccgtcat cttcggcgcg gtgatcgtgg cgggactgct
     5221 gggcttcctc gcggccccga tcttctgcaa ggcggtccgc ttcttcccgc cggtcgtcac
     5281 cggcaccgtg atcaccctca taggcgtctc cctgctgccg gtcgccttcg gctgggcgca
     5341 gggcccgaac ccggcgggga gcgactacgg ctcggccacg aacctcacgc tcgcgggcgt
     5401 caccctgctg ctcgtcctgc tcctgcgccg cttcacccgg ggcttcgtca agcagatcgc
     5461 cgtgctgctc ggcctggtcg ccggaacact cgtcgcgatc ccgttcggcg tcaccgactt
     5521 cgggcccgtc gccgccgcgg acgtggtcgg cttcccgacc cccttccact tcggcgcccc
     5581 gcagttccag ctcgcggcga tcctgtcgat gtgcgtggtg atggtggtgt cgatgaccga
     5641 gtcgaccgcc gacatgctgg cgctgggcga gatcgtcgac cgtccggcgg acgagaagac
     5701 gatcgcggcg ggtctgcggg cagacaccct cggctcggcg ctcagccccg tcttcaacgg
     5761 tttcatgtgc agtgccttcg cccagaacat cggcctggtc gcgatgaccc ggatccgcag
     5821 ccggtacgtc gtcgcgtccg gcggcgcctt cctggtcctc atgggcctgt gcccgatggc
     5881 agcctcgctc atcgccgtcg tgccgcgccc ggtgctcggc ggggcgggcg tggtgctgtt
     5941 cggctctgtc gcggcaagcg gtatccagac ccttgtccgg gccggcctgg agaaggacaa
     6001 caacgtcctg atcgtcgccg tgtccctcgc cgtcggcatc atcccgatca ccgcgccggg
     6061 cttctaccac gccttcccgg agacggcacg gatcgtcctg gactcgggca tctccacggg
     6121 ctgcgtggcg gccgtcctgc tcaacctcgt cttcaaccac ctcggcaggt ccgccgacgc
     6181 ccaggacgtg acacatccga tggaggcggg cgaggagatc accggggcga cccgggcccc
     6241 tgccacgcca tgaggtgagc gaacaactcc gcctgctcga cggcgtcgtc cagcgcgtga
     6301 tgcgtgtgac ggcgcctcgg cagcagttcc gccggcatgg aacgcttggc caccgcccgt
     6361 agcggcaccc cggccttcac ggcgtacagc gtcttcatgt ccaggcaccc cgagtgcccg
     6421 aaggggctct caccggtgaa gcggatcaga taccagtaga ggaacgtcca gtcgtacgac
     6481 gccgggtagc cgcacatcac cggctgcgcg ccctcgctca cctcgcgcac ccagcgggtg
     6541 aactggccca gtgccagggc gggatcgagc ccctcggtgc gcaggcgctc acggtcgagt
     6601 ccgctgacgg cgagcgcctc cgggacgaag tcgtcgctga cgggacgcag ttcgcggtag
     6661 aaggtccgcg cctcggggtc gcccgcggtg aacccgtcgg cgtcctgcac cccggcgacg
     6721 gccgcgccca gactgagcat cgagtagggg ccggggatcg ggccgtcggc ctcgatgtcc
     6781 acggagatgt agaggctggg tctgctgcgt cgaacggcca tgggacggga gcatcgcagg
     6841 ccgggtgcgg cccgcgcatc cgtattccga gcgaggggcg gcccgcgcac ccgtgcccgg
     6901 gtcccgcacc cgacccctaa cccgaccccg gcccctaacc cgaccccgac cggcggcagt
     6961 ctccccgccc cctcggcccc cctcccgcct ccgaacgatt cagcgggatg tgtgacggga
     7021 cggccggtcc ggtcgacgtc ggccgggccg gtcggccttg accggcccgg tcaacgcccg
     7081 ccgggtcagc ccgcgtcctg ccgccgtggc gtccgcagca ccgccgccgc cagtgccagg
     7141 gtctcgggca aatggagcgt gcagatcctc gtcgcggccg cgcacggccc gatccgcttc
     7201 accgaactgg agcgcggcat cgagggcatc agccgtcgca tgctgaccct caccctgcgc
     7261 aacctcgagc gcgacggact cgtcacccgc accgtgcacc cgacggtgcc gccgaaggtg
     7321 gagtacgaac tgacaccagt ggcacgcgag ttgcacgaga ccctgttgcg cctgaccggc
     7381 tgggcggagc gcaacagggt ctacatcgcc gagtcccgcg cggcctacga caacgagcac
     7441 gaccgggagt cggccgaggc ttaggccccc ctgggggtgc ttccggtcag agcccgaaca
     7501 ggcccggatc ggtggccagt tgcttgaagt ggtcctgggg gtcggcgacc atccggcgtg
     7561 cctgcagatc cagcaggccg ccgaccgcgg agagttcggc cgcgaccgtg ccgtccgtct
     7621 tgcggatgat ctgctcgatg cggaacgtct tgccgccgcc ccactcgaag gcgcacgtca
     7681 catcgacctc gtcgcccgcg agcagctccc gcctgtagcg gatggtggtc tccagggcga
     7741 ccggtccgac gccccggccg atcagcccgg cctgggtgat gcctgcggcc tggagcagcg
     7801 accagcgcgc atgctcggcg tagttgatgt acacgctctg gttgagatgg ccctgcacgt
     7861 cggtctcgta tccgcgcacg gtgacccgca cggaaaacgg ctcgctcacg gcttcccctt
     7921 ctcgtcgacg agcacggtcg atgccctctc caccgatctt ggcacgccct cacacccggc
     7981 gtggggaagc cagcagatag cgcgttctgc tccggggatc ggtgtgctcg cccgcctgcc
     8041 agcccgcctt ctccagggtc atcgcgcagg cgcccagcgt cccgtcgtcc ggcccgcgca
     8101 cggcgaccgc gtccggctga ggagtggcgc gcacccgata gccgtcgctg gcgggcccgc
     8161 cagcgtccgg cccgcctgcg tccggcccgc ctgcgtccgg cccgcctgcg tccggcccgg
     8221 cgggccggtg tccggccgcc tccaaagcga gcgcggcggc ctgcaccaga tgcgtacgct
     8281 cccacccgca gggccggtcc accgccccgt ccgggttggt catccggcgc agctccagca
     8341 ggccctgcca ggcactgcgc acctcccgca tccgcgacgg ccctccgtcc ggcggctgct
     8401 cctccccgcc gacccgtgcg gtgaacacgc cggtcggcgc gcgcggggca tcgaccgcgg
     8461 cggcgggacc ggcctcgggc tccgcctcgc gtatccggtg cccggccggg gtgaggaagt
     8521 ggtcgtgcgg cgcgcgcgga tgccggaagg cgaggccccg ctcgaccagg gcggcgagct
     8581 gggactccgt gccccgcagc cgcccggtga cgggatcggc ggtgtcgatc acacggcgct
     8641 gggcggcggt cggcggtcgt gtcacggcgt actccctccg ggcggcggta cggctgttcc
     8701 accgctacga aggctacggc caggcactga cagccggccc cgaccgccga cgctcccgcc
     8761 cgcccctcag gcccccggcc ggatgttcca ccccgcgatc acatggcggc cgtgctccgt
     8821 gcccagtcgg ccgagcgtcc cggtcgccag ttggaacagg gccccggccg acggcggcag
     8881 accgagcctg cgtgccgtga gcacccgcag gaagtgcccg tgcgccacca gcaccacgca
     8941 cccctccgtg ttggcgagcg ccgcgtccac cttcgccagc atccggtcgg cccgctcccc
     9001 gacctgctcc ggcgtctccc cgggatgctc cggcgggccg ggcgtgactc cgtccgtgaa
     9061 caggaaccag cccggccgtt cccgctggat ctcgacggtc gtgacgccct cgtacccgcc
     9121 gtagtcccac tcctggaggt ccgcgtcgac ccgcacctcg tgcagcccga tcagttcggc
     9181 cgtctcccgc gcccgctgga gcggactgga gaacgcggcg ccgatccggt gcgaccggat
     9241 gagcggcacc agccgccgcg cctcctcccg gccgtgctcg gtgagcggga cgtcggtcag
     9301 tccggtgtgc cggccggagc gcgaccacgc ggtctctccg tgccggacca ggaaaagatc
     9361 acccatgcag caagagtcgc acaggcgtcc gccggcgccc gcggtgcggg gcgccggtcc
     9421 gccgtacgtc cgcgatccgc ggcgtacgag acggacgcgg ccccctccga cgagccgcat
     9481 gcgcggtggg tgccgcggtg gttcccggag tcccgcccgc ggatggctgc gccggtgcgg
     9541 gcgcctccgg cgcgggccga gccagcgggg ttcgtgcggg gacggccgta cgccgcggac
     9601 gcgagcggca cgaccgcgcc gctcgtggcc ggactcgcgg cggacgcggt acggcacggc
     9661 cgggagcggg gccgtgactt ccggctccgt ccgacggccg tacccggcgg acgccacgct
     9721 ccgcgtcgac gtgacggacg cccgccccgg cgaaggccca ccgcccaccg gcctccggag
     9781 cgctcccgcc gtccgcgccc gacgcggagt ccggcggggg cctcctcctc gaggcgccgg
     9841 ccacccactg ggtggacggg cggcggcccg tccaccaggg cggtgtggtg cggggtcgcc
     9901 ctcggccgac ggccccgaca ggttgtcgcc tactgtcggt aaccgctcag gaaacgcccg
     9961 atccgcccga tcgccgcctc caggtcctcc gcgtgcggga gggtgaggat gcggaagtgg
    10021 tccggggtcg gccagttgaa tccggttccc tggacgacct ggatcttctc gcgcagcagc
    10081 aggtccagga cgaacttctc gtcgtcgtgg aggggatgga ccttggggtc gatgcgcggg
    10141 aacgcgtaca gcgcgccctt gggcttcacg caggagacgc cggggatctc gttgagcttc
    10201 tcccaggcga tgtcgcgctg gtcgcgcagt ctgccgcccg gcccggtcag ttcgcggatg
    10261 gactggcggc cgccgagcgc ggcctggatg gcgtactggg cgggcgcgtt ggcgcacagg
    10321 cgcatggagg ccagcatggt gaggccctcc aggtagtccc gcgcgtgctg cctgggaccg
    10381 gtcaccacga gccagcccga gcggaaaccg gccacccggt acgtcttgga gaggccgcag
    10441 aaggtcagga cgaccaggtc gggggcgagc gcggcggccg agtggtgcac ggcgtcgtcg
    10501 tagaggatct ggtcgtagat ctcgtcggcg aagaccatca ggccgtggcg gcgggccagg
    10561 tcgaggatgc cctcgatgat ctccttgggg tagaccgcgc cggtggggtt gttcgggttg
    10621 atgatgacga cggccttggt gcggtcggtg atcttggacg ccatgtcgtc caggtccggg
    10681 taccagtcgg cctgctcgtc gcagaggtag tggaccgcct tgccgcccgc gagcgtggtg
    10741 acggccgtcc acagcgggaa gtcgggggcc gggatgagga tctcgtcgcc gtcctcgatc
    10801 agcgcctgta cggccatgga gaccagctcc gagacgccgt tgccgagcca cacgtcgtcg
    10861 acgtcgacct ccaggccccg gtcctggtag cgctgggcga ccgcccggcg ggccgtgagg
    10921 acgccacgcg agtccgtgta gccgtgggcc cgcgggagca tccggatcat gtcctggagg
    10981 atctcctccg gcgcctcgaa gccgaagagc gcggggttgc ccgtgttgag gcgcagcacg
    11041 ctgtgccccg ccgcctccag tgcgttggcg tgctcgatca ccgggccgcg gatctcgtaa
    11101 cagacctcgc tgagcttgtt cgactgccgg aactccatgc gcccctccgg tatctggtgt
    11161 tacttggttt taccaagttc gagcttggaa agtccaacga catgtctaga ctgcgtcgca
    11221 tgccacctcg ccgaagctac gaccagtact gttccgccgc ccgcgccctc gacaccgtcg
    11281 gcgaccgctg gaccctgctg atcgtccggg agctgctcgc cggcccgcgc cgctacaccg
    11341 acctgcacgc cgacctgccg ggcgtcagca cggacgtact cgcctcgcgg ctcaaggaca
    11401 tggagcgcga cgggctcgcc acccggcgcc ggctgccgcc gcccggcgcg gccaacgtct
    11461 acgaactcac cgggcgcggc cgtgcgttgc tgcccgtgct ccaggcgctc ggtgcgtggg
    11521 ggcaggcgga actgggcgag cgcgggccca ccgacgcgat ccgcgcgcac tggttcgcgc
    11581 tgcccctgct gcgcgccctg gagggcgagg gactcgtaga agtccgcctg gacgagggcc
    11641 acttccatct cttcgtcggc acggacgaag ggcccgtgta cggccacggt gcggcccccg
    11701 gcgaacccga cgccctgctc gtcatggaca ccgccacctg tacggccgtg gcccagggtg
    11761 tgctgagcct gctcgacgcc gtgcgcgccg gacgcgtcga ggtgagcggc gagggcaccc
    11821 tcgccaaggg gctgcggcag gcctgagaac gcggaaggcc cgcacggggc gggccttccg
    11881 cgtggacgtc agacgcccgg cggtacgttt ctcggccgtc ccggaccgcg ggtcagggcg
    11941 tacccgccga tcccggcgag cgcggccagc acgccgccga tcccggtcca cacccagcgg
    12001 tccgaccacc agccggacga ccagccgtcg tccggctcga tgctcgacag cacggcggag
    12061 gccgacgggt cgtcctcgtc ctccgccgac gacttcacgg cgacgcccgg caccaggggc
    12121 tcggccagcg agccgtccac ggccgccgaa ccgccgatgt ccttggagtc gacgcgcagt
    12181 tcggcgccga ccggcagacc gaggtcggcc gtcttcagac cgacgaccgt cagacggacg
    12241 tagtacgtgc cgggcagcgg gtcgtcggcc cacggctccg accaggcgcg gaccgtgcgc
    12301 aggacgcagg ccagctccag cgaggcggtg ccgggcgcgg cggtgcgggt ctgcgcgccg
    12361 tactggcagg actggcggcg ccgcagaccg tcgtacacgt cgacctgcca ggtctgcccc
    12421 gcgtgctcct cgggcagctt caccttcgcc gtcacggtgg gccgttggcc cgcgtcggcc
    12481 gggaacgacc agtacaggta gtcgcccgcg gagccgctcg cggtggccgt ccgcccctgg
    12541 tcgacctccg tcgccgtacg gaacgacgtg ccggccgtcg tgggtgccga accgtcctcc
    12601 gacgggctcg cggacggggt ggagtcggcg gcggccgggg tggccgccag gccgagcgcc
    12661 aacagggtcg tgctcagaac acgggtgata cgcatcagtt ggtcctccag accgcgacac
    12721 gccagcgtga cagccagccc cacaggacgc ccgcgaggaa gccggccagc accagggcgc
    12781 cgagcagcca ccagccgcgg ccgagaccga acgaggccac gtcgctcgcc tgcgacggtc
    12841 cgtcgaccac gtccacggtc agctccagcg gcatgcccgg cgtggtcttc acaccggccg
    12901 ccgccgaata ggagttggtc acctgcacgc acaccgtctc ggcgggcgct tcgtcgtcgt
    12961 cgctctccgc cttcgggtag cgcagaccgg tcgagatgac gtcggtacgg ccgttcccgg
    13021 ccgcctcgcc gcgcacgatc tcccggccgt gcaccgtcac cgcccgcacc agcaacccgt
    13081 agtcggggtt catcgcccgg tccgccgaga cgctcaccga ggcccgcagc tccttgcccg
    13141 ggtccaggtc cacgcggtac cagcgctcct ggccgaactc ctcacggtcg gtgtaaaggc
    13201 ccgacttcag cgtcggcgcc ttcgcgcagg agtccgcgcc ccgggtggcg accggcgtca
    13261 ccacggggtc ggccgcgcgg tccaccaact ggtttacctt gtcggtgagt tcgtcggtgt
    13321 gctccaccga ggtgtaggtg ccgcccgtgg cctcggcgat gcagctgagc tgctggcgca
    13381 tcttcacgtt cggcaccagg ccgagggtgt cgatggtcag gccgatgccc ttggccgcta
    13441 tctcgcgggc cacctcgcac gggtcgagcg gggcgcaggt gtcctcgccg tcactgatca
    13501 ggacgatccg cttggagccg gtgcccccgt cgaggtcctc ggccgccttc agcagggccg
    13561 gtccgatcgg ggtccagccg gtgggcgtga gcgtggccac cgcggccttg gcctcggtac
    13621 ggtccagcgg gccgaccggg tagagctggg cggtgtcctt gcagccggtc ttctggtcgt
    13681 cgccggggta gttggccccc agggtgcgga tgccgagccg gacctcctcg ggggtcgcgt
    13741 ccagcacctc gttgaacgcc tgcttggccg cggccatccg cgacccgccg tcgatgtcct
    13801 tcgcccgcat ggaaccgctg acgtcgagaa ccaggttgac cttgggcgca ttggctgtgg
    13861 tcccgtcggc gaccgccccg gccgggaacg cgagcccggc cgtgagcgcg gcgagcaggg
    13921 cgcacaagcc cgccgccagc cgttgtgttc tgatcatcgg cggatcctat tgatcagagg
    13981 tgtccggctt caaaacgtga tcagaaagcc cgggtgacca aagggttggg cagccgcgcc
    14041 caccggtccc cggacccgcc gggcgacagc cgcatcagcg tcagcgcctt caccggcacc
    14101 ggctccccgc gcagcgcccg caggtccccc gtgtccggca cctccggtac ggccgccgcc
    14161 agcgccgtgc ccagcgcctc cccgctgccc gcggtggccg ccagcgcgcc cgccaccagc
    14221 gagccgaaca gtttgccgcg cagcgccgtc acgtcgtcgg tcaggatccg ggccggcagc
    14281 tcgggcgccg ccaggccgtg ccgggccagg cgcgccgggc tgacccggat gtcggcgagg
    14341 tcgcggtaga cgagccgcac cggtgccccc gacgccgaca gcacgaccag caggttctgg
    14401 ccgtgcgcct ccaacgccac gccctgctcc agcagccgca gccccacggt gagcgcgaga
    14461 cgcgcgaagt cggccaacca ggcgggtgag gacgtcagtt cggtggtggc gagggcggcc
    14521 accgggacga cgtgctcgcc ggggcccgcg tacacggcgg gggactcccg cagcacggcc
    14581 gcgagatcag gggagtcggc cgtgaccgcg cccagtgagc gggtcatgtg cagcaggccg
    14641 tccgtgcgtt ccgccaggct ctccgcgaac gccgacaggg ccgaggaggc ggcgaccgag
    14701 cccaccgaga tgtcccgcac cgacgacgtc agccgggcgc tcaacgccgt cttcacgtgc
    14761 gggccgtccg gcaccgcgag cgtgcgcagc gacatcagcg gatgcgccgc gagcccctcc
    14821 acgcacgacc gcttcagtac gtgcgccgcc tgccacggat gcaccgggat caacagcctc
    14881 cgcccgtcgc gcagttcggc gggccacccg cccgagacga gacactcgtc ggccgggacg
    14941 ggcagcaggc ccagccgcac cgccggcggc cggtgctccg gcccgtaggc cagctgttcg
    15001 gccaccgaga aacccggccg ggaacgacag ttggggtggt acgggtgccc gtcgaccacc
    15061 cgctgctccc actcccagtc gtgcgcgggc catccttcga cgtcgccggc gccgggctcc
    15121 ccgggttgct gtccggcccg ggacagcgcc aacgacgccg tactgtgcgc cagttcgcct
    15181 gcgaggccgc cgccgtacgg cacggccagg tccgtcatca gccgcgcggg atcgtcgaac
    15241 gccgtcccgg ccaggtccac ggccgtcacg taggcggcgg tcgcgtacgg gtcggcgtgc
    15301 gggccgtgca gccggcggcc gtcggcgagg tgcagggtca ggccgtcccg ggccgccgcc
    15361 cggcgtacga cccacggcag cggctcgtgg gcgagggccc gccacagacg ggtcagcacg
    15421 gccgcgcggg cgccggacag ctcggccgcg aaccgcgcgg cgagcgcggg gcgcacggcg
    15481 gcgaggtcgg cggccagctc ggcctcggcg gtggggggac ggtgcacggg agggctcctc
    15541 gggtacgggt cgggtacggc tcgggtgggc gcagggcgtc acggacgggt cgtgaccaca
    15601 gcgatactga tcgtctccgc ccgcaagaac cgtagggaac gagtggaacg cgtggttctc
    15661 atccccccac ccgccgggtc ggcgcccgcc gagcccgatg cggccaccag gtccgacgca
    15721 ccggccgacg cgaccggtcg ccgcgccgac gcgaccggtc gccgcgccga cgccgcggcg
    15781 cggggcgcga tcgccgcacg cgccgacgcc ctcgccgccg cgccgctgct caactgcctg
    15841 ctgcgggaag tggccgtacc ggaggcggct gaaccggaag cggccgaacc cgaggcggtc
    15901 gtacccgaag tggtcgaacc ggacgcggct gaccccgaag cagctgaacc cgaagcggcc
    15961 ggaccggagg cggccgaacc cgaggcggtc gagcccgaag cggccgaacc ggaaatggcc
    16021 gaacagcaag tgcacgaacc ggaagtcgcc gaacggcaga tggccgaacc gcgctcccga
    16081 cgcggcgccc ggcaggtgca ccggctgccc tccggccgtc tgctccgcgt gcgcggcgcc
    16141 cggcggccgg ccgagcccga ggtgcgcgcc gacggcgcct ggcaccgcct cgaccaccgc
    16201 ggcctcgtcg acctggtcgc cacggaactg cgccaccaca ccggcctcac caaccccgag
    16261 ctgcccgccg agatgctcga cagccgggac gcggtggccg ccctcctcgc cgcacgcgcg
    16321 cgtgccaccc cgccggagga cccctacctg cgctccgagc agtcccttct caccggccac
    16381 ccccaccacc ccgcccccaa gacgcgcggc ggcggcccgc ccggcggctg gctgccgtac
    16441 gcgcccgagg cgtacgcccg cttcccgctg gtcctgctgg ggctgcgcga ggacacggtg
    16501 gtggaggacg gtgacaccgc cgcgctggac gccctcggcg aggccccgcc cggctaccgg
    16561 ctgctgcccg cccacccctg gcagctcgac ctggcccgca ccgcgctcgc ccccgccttc
    16621 gccgacggcc gtctggtccg gctcggcacg acgcccttcg acacctggcc cacggccgcc
    16681 gtgcgcacgc tgtacgcacc cgggccggac ctgttcctca agttcagcct cgacgtgcgc
    16741 atcaccaacg acatccgccg gctctggcgc cacgacctgc tgagactccg ccggaccgac
    16801 gcggcggcca cgcgggccct cgcggcggtc ggcggccccg ccgcctggct cagcgaccgc
    16861 gggtaccgca ccgccggctt cgccttcgag gaactcgccg tgatggtccg cgacgggctg
    16921 cacgcgcacg tcacgcccgg cgcgaccccg ttgctcgccg cgggcctcgt ggagggcttc
    16981 gagggcagcc cgctcgccgg cacggccgac ccggcacact ggtgggaggc gtatctggcg
    17041 gccgtcgtcc ccccggcgct ggccgcgttc gccgaccacg gcgtcgtgct ggaggcccac
    17101 ctgcagaaca ccctcgtcgc cgtcgacagc gccggacggc ccgtgcaggc cctcttccgg
    17161 gacgccgagg gcgtcaagct gctgcccgag acggagcgcg ccgcgggctg ggagcggctc
    17221 gtgtactgcc tggtcgtcaa ccacctcacc gaggtcgccg ccgccctggc cgaccaccac
    17281 cacggtctcg atccctggcc cgccgcccgc cgcgagctgg cccgtcacga cctccccgag
    17341 gtccacgccc tcctcgcggc gcccaccctg cccggcaaga ccaacctcct gctgcgctgg
    17401 acgggcgcgg acggtgccga cgcccgctac ctgcccctgc ccaaccccct ggccggcagc
    17461 tgacctgaac tacgctggcc ggtgtgctgc gcgacgtgac tgctgttcga tacgtgaccc
    17521 cgctgaggtc cggcggctcc gtgcccgcgg tcgtcgaggc cgacgacctg gggacgtacg
    17581 tcgtcaagtt caccggctcc gcgcagggcc gcaaggcgct ggtcgccgag gtgatcgtgg
    17641 gggagctggc gcgggccctg gggctgcgct tccccgagct ggtcctggtc cacttcgacc
    17701 cggcgatcgc cgacggcgag ccccaccagg aggtccgcga tctgcacgcc gccagccacg
    17761 gggtcaacct cggcatggac cacctgccgg gcgcccggga cttcaccccc gacatcgccg
    17821 aggtcttccc ggtggacccc ctcgaagccg gccggatcgt ctggctcgac gccctcaccg
    17881 tcaacgtcga ccggaccgtc cacagttcca acctgatggt gtggcccacg ctcggcaccg
    17941 tgccgccgcg cctgtggctc atcgaccacg gcgccgccct cgtcttccac caccgctggg
    18001 acggctccga cccggcgaag aggtacgact tccgtcacca cgccctcggc cgctacgccc
    18061 ccgacgtacg ggccgccgac gccgaactgg cgcccagggt caccgaggag ctgctgcggg
    18121 cgatcgtcgc gcaggtgccg gacgcctggc tcctggacga acccgccttc acgagcgccg
    18181 acgaggcccg gacggcgtac gtgaaccacc tgcacgcgcg cgtgcgggcg tccgcggcct
    18241 ggctgcccac aaacttcccc acccgcgacg aactcgccgc cgaagaggcc cggcgggccg
    18301 cgaagacccg gcaaggacgg cccgactggc tgaagcgggt ccccgacctg cacggcaagc
    18361 cggccgcgga acaggattgg tcggtacacc tcggatgacg gacacacggc ttgacggaag
    18421 cggcccgcgg cgggtcgaga tcgagtactg cacccagtgc cgctggctgc cccgcgccgc
    18481 ctggctcgcg caggagctgc tcaccacctt cgagggggag ctgaccgaac tcgccctcag
    18541 gccgggcaag ggcggcgtct tcgtggtccg ggtgaacgac gaggtcgtct gggaccgccg
    18601 cgagcagggc ttcccggagc cgaccgcggt caagcggctc gtccgcgacc gagtggcccc
    18661 ggggaagtcc ctgggccact cggacaagcc ggaatgagcc ttctcggggg tcagcccgtg
    18721 agctgctcgt aggccggcag ggtgaggaag tcggcgtagt cctcgtccag ggcgaccgtc
    18781 agcagcaggt cgtgggcctg ctgccagtgg ccggccgcga aggcctcctc gccgatctcc
    18841 gaccggacgg cggccagttc ggcggcggcg acctcgcggg ccagctccgg ggtcaccctc
    18901 accgtcgtac cgtcgcggtc gacctcgacg cccgcgttga tccactgcca gatctgcgag
    18961 cgcgagatct cggccgtggc cgcgtcctcc atcaggttga agatggcgac cgcgcccagc
    19021 ccgcgcagcc acgcctcgat gtaacggatg ccgacctgca cggcgttgac gagaccggcg
    19081 tacgtcggcc gcgcctccag agagtcgacg gcgagcaggt cggccgcctt gacgtcgacg
    19141 tcctcgcgca gccggtcctt ctggtggggc ctgtcgccga ggacccggtc gaaggactcc
    19201 atggcgatcg gcaccaggtc ggggtgggcg acccaggaac cgtcgaaacc gtcggcggcc
    19261 tcccggtcct tgtcggcccg caccttctcg aaggcgaccc tgttgacctc ggggtcccgg
    19321 cgcgagggga tgaaggccgc catgccgccg atggcgtggg cgccgcgctt gtggcaggtg
    19381 cgcacgagga gttcggtgta cgcgcgcatg aacggggcgg tcatcgtcac cgcgttgcgg
    19441 tccggcagta cgaacctggc gccgccgtcc cggaagttct tcacgatgga gaacaggtag
    19501 tcccagcggc ccgcgttcaa cccggaggcg tggtcgcgga gttcgtagag gatctcctcc
    19561 atctcgtacg cggcggtgat cgtctcgatc aggacggtcg cgcgcacgct gccctgcggg
    19621 acgccgacct ggtcctgcgc gaacacgaac acgtcgttcc acaggcgggc ttcgagatgc
    19681 gactcggtct tcgggaggta gaagtacggt cccttgccga ggtcgagcag ccgctgggcg
    19741 ttgtggaaga agtacaggcc gaagtcgacg agggcgccgg ggaccgcccg gccgtcgacc
    19801 tggaggtggc gttcgtccag gtgccagccg cgcggacgca tgacgacggt cgccagctcc
    19861 tcggccgggc gcagggcgta cgacttgccg gaccccgggt cggtgaagtc gatgttcccg
    19921 ccgtacgcgt cgatcaggtt gagctggccg acgacgacgt tctcccaggt cggcgcggag
    19981 gcgtcctcga agtcggcgag ccagacccgc gcgcccgagt tgagggcgtt gatggtcatc
    20041 ttgcggtcgg tggggccggt gatctcgacc cggcggtcgt cgagcgcggc gggcgcgggg
    20101 gcgaccctcc aggagtcgtc ggcgcggatc gcggcggtct cggggaggaa gtcgagcgtg
    20161 gaggtgcggg cgatctcggc gcggcgctcc gcgcggcggg cgaggagttc gtcacggcgg
    20221 ggcgtgaacc gccggtgcag ctcggccacg aaggcgaggg ccgcgtcggt gaggacctcc
    20281 tcctgccggg gcaggggctc ggcgtcgacg acggccgccg gggacggcac ggatgcggac
    20341 atgagctgtc acttccttca gcgagcgtgg caccgggtgc cggacgaccc gggtggggcg
    20401 gggagcgctc ggagagcgac cgaacgcttc tgagcagtgg attctagttt ccttatcgtg
    20461 gaagttcaat ggtttgttga tgtcgagatt ctccgggtcg agggaaggtg gctctccgtg
    20521 ccacctcgtt cactccaggt gggccaggtc gtccaccgtg tcgatgtcgt acggccgggc
    20581 cacgtccccg cactccacca gccggatctc ctcctcgtgt gccttcaggt agtcgcgtgc
    20641 cccccggtcg ccggtcgcgg tcgccgtgac accggcccag tgggccgccc cgagcagtac
    20701 cgggtgcccg cgcctgccgt cgtaggcggc ggacgccagc gactcctcgt cctcgtacgc
    20761 ggcgcgcacc cgcgccagcg cccgaccgcc gatgcccggc tggtcgacca gcgagaccag
    20821 ggcggcccgc gcccccgtcc cggccagcga gtccagaccg gcccgcagcg agccgcccat
    20881 gccccgctcc cactccggat tcaccaccgg cacgcatccg tcgagccgcg cccgctcccg
    20941 tacggcgtcg gctgcggccc ccaggaccac gtgcacgcgc gtgcagcccg ccgcgcgcag
    21001 ggcctccacc gcgtgttcga cgagcgggcg cccccggtgc gtcaacagcg ccttggggcg
    21061 tccgccgagg cgccgccccc cgcccgcggc gaggagtagt ccggcgacct ggtcttccgt
    21121 gtgcgtcatg tgttctgcat acctgacggg gtggcggccg ggcggtgtcg cagggctgaa
    21181 tttcgttccc cggtgtggcg gagcgggtgc cgggtggcgt ttactggccc gcgtcctcac
    21241 ggcgcctgac caccgtcacg gggacactgt gtacgtacgc atgagggatg tgcgaggggg
    21301 agagctgtgt tgcggagctt gggacagagg ctggtgaccg gcagcgacga ggatccgagg
    21361 gtggcggaac tgcggaccgc ggtgtcccgg ctgcgccgcg aactcgccgc gcacccggcc
    21421 gagttcccgg accggggcat cgccgaggac gaactcgccg cgctcgccgc gatggcggcc
    21481 cacggcatcc cggagatccc ccggctgcgc cgctccctgc tgctgatcgc gggcgcgatc
    21541 ggctcggtga gcgcgctggc gcgaggggtg tcggacgtgc gcagcgcggt ggagctgttc
    21601 ggggagtcgc cgcagaggtg acggaccgtc agtcgtgcgc gggtgccggc acgggcacgg
    21661 gtgcgggcat ggcccggctc agacgctcgt accgcccggg ttcgacagga cctcggacag
    21721 ttccagggcc acctgctgga gcaccgggac gatcttcccg gtggcggact cggtgacgcg
    21781 gcccgccggg ccggagatcg agatggccgc cgcggtgggg gagtcgggca ccgggaccgc
    21841 gaggcagcgc acgccgatct cctgctcgtt gtcgtcgacc gcgtaaccgg cctcgcggac
    21901 ctcgtccagg gccgccagga agccctccgg ggtggtgatc gtcctgtccg tcgcggccgg
    21961 catgccggtg cgggcgagca gtgcgcgcac ctcggtgtcc gggaagcccg cgaggagggc
    22021 cttgcccacg cccgtggagt gcggcaggac ccgacggccg acctcggtga acatccgcat
    22081 cgagtgcttc gacggcacct gcgccacgta cacgatctcg tcgccgtcca ggagtgccat
    22141 gttcgccgtc tcgccggtct cctcgaccag gcgggccagg taggggcggg cccaggtgcc
    22201 gagcagtcgg gcggaggact cgccgaggcg gatgagccgc ggaccgagcg cgtagcggcg
    22261 gttggactgc tggcggacgt atccgcaggc gaccagagtg cgcatcaggc ggtggatcgt
    22321 cggcaacggg agcccgctgc tcgcggacag ttcgctgagg ccgacctccc cgcccgcgtc
    22381 cgccatccgc tccagcaggt cgaaggcgcg ctcgagggac tggaccccgc cgctgccgga
    22441 cttggcggag tcggtggtgc tggcgctgga cgtcggcacg ggcgcgttcc tttccaaact
    22501 ggcgggaggg gctgaagcct acccgcggtc ggtcgactca ccgctggtgc gtagcctcgt
    22561 tctgcttgcc ggaataataa ttccgtcttg tggaaacgtc cagagtggcg gccgcgggtg
    22621 cactgtggag aggtgggccc ttgacggcgc ggtggccggg agtgaagact ccttcaacag
    22681 aacgttgaat tccgttacgg ggaggttgcg cggaagtgcg ccctggagcg cgtccccggc
    22741 cgcctccgtc tcccggaagc aaacggcggc agagaggggt tcgggtgtcc gacgctgaac
    22801 tggtgctgcg ctcgacgcgc gtcatcactc cggaagggac acgcgccgcc tcggtcgcgg
    22861 tgtccgccgg caccatcacg gccgtacttc cgtacgacgc cgccgtaccg tccggcgccc
    22921 gcctggagga cctcggcgac gacgtcctgc tgcccggcct cgtggacacg cacgtgcacg
    22981 tcaacgatcc aggacgcacc gagtgggagg gcttctggac cgccacccgc gcggcggccg
    23041 ccggcggcat caccaccctc gtcgacatgc cgctcaactc cctcccgccg accacgacgg
    23101 ccgaccacct ccgcaccaag cggcgggtgg ccgccgacaa ggcgcacatc gacgtcggct
    23161 tctggggcgg cgccctgccc gacaacgtca aggatctgcg cccactgcac gaagccggcg
    23221 tcttcggctt caaggcattc ctctccccgt ccggtgtgga cgagttcccc cacctcgacc
    23281 aggaccacct cgcccgctcc ctggccgaga tcgccggatt cgacggcctg ctcatcgtgc
    23341 acgccgagga cccgcaccac ctcgaatccg cccctcagcg gggcggaccc aagtacgccg
    23401 acttcctcgc cagccgcccg cgcgacgccg aggacaccgc cgtcgcgagc gtgatcgccc
    23461 aggcgagacg cctccacgcg cgcgtgcacg tcctgcacct ctcctccagc gacgcgctcc
    23521 cgctgatcgc cgccgccaag gccgagggcg tacgcgtcac ggccgagacc tgcccgcact
    23581 acctcaccct caccgccgag gaagtgcccg acggcgccag cgagttcaag tgctgcccgc
    23641 ccatccgcga ggccgccaac caggacctcc tgtggcaggc gctggccgac ggcaccatcg
    23701 actgcgtggt caccgaccac tccccgtcca ccgccgacct caagaccggc gacttcgcca
    23761 ccgcctgggg cggcatctcc ggcctgcaac tcagcctcgc cgccgtctgg acggaggccc
    23821 gcgcgcgggg ccacggcctg gaggacgtcg tccgctggat gtcgacgcgc acggcggcac
    23881 tcgtcggcct cgaccgcaag ggcgccatcg aagcgggccg ggacgccgac ttcgcggtcc
    23941 tcgcacccga cgagaccttc accgtcgacc cggccgccct ccagcaccgc aaccgggtca
    24001 ccgcctacgc cggcaaaacc ctgcacggcg tcgtgaagtc cacctggctg cgcggcgaac
    24061 gcatcgtcgc cgacggcgag ttcacctccc ccagtggccg gctcctcacc cgcgcccact
    24121 gacccacccc gcacccgccc gcacgcggcc gactcccgaa aggaacccct gatcaccgtg
    24181 acggcgcagc atcagtcttc gttggccggc ttcaccggcg acgcgaaccc ctacggcggc
    24241 ggcgacccgt acgcggacta ccgcaccgcc gacttcccct tcacctcgta cgccaacctc
    24301 gccgaccggc agctcggcgc cgccgtcatc gccgccaacg acgagttctt cgcccagcgg
    24361 gagaacctgc tgctgcccgg accggccgag ttcgaccccg agcacttcgg gcacaagggc
    24421 aagatcatgg acggctggga gacccgccgc cgccggggcg tctccgccga ccacccgtgg
    24481 ccgacggccg acgaccacga ctgggcgctc gtccggctcg gtgcgcccgg cgtgatccgc
    24541 ggcgtcgtcg tcgacacggc ccacttccgc ggcaactacc cgcaggcggt gtcggtcgag
    24601 ggcacctcgg taccgggctc gccgtcgccc gaggccctcc tcggggacga cgtgaagtgg
    24661 acgacgctcg tcccgcggac ccccgtcggc ggccacgcgg cgaacggctt cgccgtctcc
    24721 gtcgaacagc gcttcacgca cctgcgggtc aaccagcacc ccgacggcgg catcgcccgg
    24781 ctccgcgtgt acggcgaggt cgtcccggac cccgagtggc tggccgtcct cggcaccttc
    24841 gacgtcgtcg ccctggagaa cggcggcctg gccgaggacg cctccgacct cttctactcg
    24901 ccggccggca acaccatcca gccgggccgc tcccgcaaga tggacgacgg ctgggagacg
    24961 cggcggcgcc gggaccgggg caacgactgg atccggtacc ggctggcggc ccaggccgag
    25021 atccgggcgc tggagatcga caccgcgtat ctgaagggca acagcgcggg gtgggcggcg
    25081 gtgtccgtgc gggacggtga ggagggggag tggcgggaga tcctgccgcg cacgcgcctc
    25141 cagccggaca ccaaccatcg cttcgcgctg gccgccccgg cggtgggtac gcacgcgcgc
    25201 gtggacatct acccggacgg gggcatctcg cggctgcggc tcatcggctc cctgacggac
    25261 gccggcgcgg gcgccctccg ggcgaggcac caggaactgg gcggctgagc cgggttccgg
    25321 tcccggcccc ggggctccgc ccccggaccg cggctgagcc gggttccggt cccggccccg
    25381 gggctccgcc cccggaccgc ggctgagccg ggttccggtc ccggccccgg ggctccgccc
    25441 ccggaccgcg gctgagccgg gttccggtcc cggccccggg gctccgcccc cggaccctgg
    25501 tccacgccca caccgcccaa cccggtggga cgaaaggcgg ggccgacagc ggggtccgag
    25561 ggccctgctc ctggctcacg ctggggacgg ggcctctggt ccaggctgtg ggccctgccc
    25621 tcggttgggg ctgtgggccc tgcctctggc tcgcgctggg gacggggcct ccggctcggg
    25681 ctgtgggcct gtctctggct catgccgcgg accccgcccc cggctcacgc cgtggacggg
    25741 gcctctggct cgggctgtgg gcctgtctct ggctcatgcc gcggaccccg ccccggctca
    25801 tgccgcggac cccgccccgg ctcatgccgc ggaccccgcc ccggctcatg ccgcggaccc
    25861 cgccccggct catgccgcgg accccgcccc ggctcacgcc gcgggcgggg cctccggctg
    25921 gggctgtggg cggggcctcc ggcccgggct gcgggccctg cccccggctc acgccgcagg
    25981 cggcctcccg ctcacgccgc gtggcccccg tccaccgcgt actccgcccc cgtcacgtac
    26041 gtggcgcccg ccaggtacgc caccatcgac gccacctcgt cccccgtccc gaaccgcccc
    26101 agcgcggtca gcgccgcctg acccgccgcg tacggcccgt ccgccggatt catgtccgtg
    26161 tcgatcggcc cgggatggac gaggctcgcc gtgatccccc gcggccccaa atccctcgcg
    26221 agccctttcg tcagcccgac cagcgccgac ttgctcagcg cgtacagcgt ccccccgggc
    26281 cccggcaccc gctggaccat gcagctgccc acggtgatga tccgcccccc ggcgcccatc
    26341 cgcccggcgg ccgcctggga ggtgaggaag acgccccgca cgttcaccgc gagcacccgg
    26401 tccacgtccg cgagcgacag gtcctccagc ggcccgagca ccccgatccc cgcgttgttc
    26461 accagcacgt cgagcccgcc cagcgcgtcc gccgccgcac cgaccgcccc cgccgcctcg
    26521 gcggcgtccg cggagtccgc gcgcagggcc accgcacggc gtcccagggc ctcgacggcc
    26581 cgtaccacgt cctcggccgc ctccttgccg ttcacgtacg tcagggccac gtccgcgccc
    26641 tcccgcgcca gccgtaccgc cgtcgccgca ccgatgccgc ggctgccgcc ggtcaccagg
    26701 gccaccttgc cgttcagggt cttgtccgaa gtcgtcatgg gtccatccca gcgccacacg
    26761 ccccggcgcg ctggcggcga acggacgccg acctcggcga tgagttgcgg ggcgggacgg
    26821 tgtctgacct gatgacaggg gacctcaccc cgagtaccag caaaggaggg cacccgtcat
    26881 gggcaagctc gtcctcaccg gtttcgtcac cctcgacggc gtccaccagg cgcccggcgg
    26941 cccccacgag gacccccgcg gcggcttcgg gcagggcggc tggagcgtgc cctacggcga
    27001 cgaggacttc ggccggttcg tcaccgaggt cttcgaccgc gccggtgcct tcctgctggg
    27061 gcggcgcacc tacgacatct tcgcctccta ctggccgaag gtgaccgacc ccgccgaccc
    27121 ggtcgcctcg cggctgaact ccctgccgaa gtacgtggcc ggctccgcgc cgctcgccga
    27181 cccggtctgg ccgggcgcca ccgcggtcca cggcgacctc gtcaagcagg tcaccacgct
    27241 gaaggaacgc accgaaggcg agctccaggt gcacggcagc ggcgccctgg ccgccagcct
    27301 gctcgccctg gacctggtcg acacgctgca cctgctgacg ttcccggtgg tgctcggcgc
    27361 cggccgccgc ctcttcgccg agggcgcccg gccgaccgcg ttccggcaca ccggggggcg
    27421 ggtcaccgcg gccggggtct ccatccagac gtacgacctc gacggacggc cgagctacgg
    27481 gacgtacgaa ctcccggacg gggtctagcc ctcctcgccg aacccgctac ttccgccaga
    27541 acagccgaac ccgctacttc cgccagaaca ggtggtgcgt cacgccgctc gggctgggca
    27601 cgacctccag gtggtaccgg tcgagcagtt cgtcgggcga gtcccagagc ttcagtccgg
    27661 agccgagttc caccggcgag accgccacgt ggagggtgtc gacgaggccg gcgtcgagga
    27721 actgccggac ggtggtgacg ccgccgccga gccggacgtc cttgccctgc gccgcttccc
    27781 gcgcccgtgc gaggaccgcg gccgggtccc cgccgacgaa gtggaacgtg gtgtcggaga
    27841 gcgtgaacga ggggcgctcg tggtgcgtca tgacgaacac gggcgtgtgg aacggcggtg
    27901 cgtcacccca ccagccgcgc cactcgtcgt cctgccaggg gccgcgcagg ggcccgaact
    27961 tgttgcggcc catgatctcg gcgccgatgt tgcgggcgta gtcccgggtg aagtggtcgt
    28021 cgaggccccg gctgcctccg gggtcggtgc gcatgggcca gctcgccgtg gcgccggccc
    28081 aggcgaagag cctcccgggg tcgacgtggc cgaacggccg ctcgaagctc tggtcctcac
    28141 cggcaccgat gccgtcgctc gagacgttga agttctggac tctcagcagt tgggccacgt
    28201 gttcctcctg gtgctgtggg cgacggaggt gagaccgtcc gcgcggcggt ttctcatcgg
    28261 tccgcccgcg gcaggttaac tcccggaaaa ctcagcagac ttggcgggaa attctgagag
    28321 ttgtcattga catgccatca tctacgcgcg tcatcatgga gccatgagat tccccccacg
    28381 aatcactcgc atcggcggcg ccgccgccct cctgtccgcc ctcctcgtcg gcggcaccgt
    28441 ctccgccgga tcggcgaacg cggcggcgac cgcggtcggc agcatctgct acagcgacct
    28501 gccctcgcag gcgtacacca cgctgcggct gatcgaccag ggcggcccgt tcccgtactc
    28561 gcaggacgga tccgtcttcc agaaccggga aggcatcctg ccctcgaagt cctcgggcta
    28621 ctaccacgag tacacggtca agacaccggg ctcctccacg cgcggcgcgc gtcgcatcgt
    28681 gaccggacag cagaccgaag aggactacta caccgccgac cactacgcga gcttcgacct
    28741 ggtcgaccac gactgctgag ccggctccgg cgaccgactc cggtcgccgg ggaacgggtc
    28801 accgaggaac ggcgccaccg gccgggggcc cggcccgcgc tcagccgggc ttccggctct
    28861 ccgcggcggc gaacagggcg aacgcgagca ccaggagcgc gacgctcgcg tagacctcgt
    28921 agccgtcgag gacgccgagc cgctgcacga gtccccagtc caggtcggtg aactcgtgca
    28981 ccaggccggc gacgccctgc accagggcga tgaatccgag tacctccaga agctgcttca
    29041 taccccggac cctcgccccg cggtcccccc acacgcatcg gccgcggggc gagacgctcg
    29101 cgaccgaagg ctctcgtcgg cggcgcgcag tacaccgtcg gtcggcggcg gtgcgacttt
    29161 cgtcggtgtc cgtccggcgc aggtctccga tcccggccga ggaagggtga ggcggccccg
    29221 agctgcgtag atttgtcgac catgaggggt gacgaccggc cgacgccggc accggaggca
    29281 gcgatcttcc cgacgcggcg atggctgctg ccgtccgccg tggccgcgga accggacccg
    29341 gacgccggac ggccgggcag ggcgccccgt cgcaccgccc gcgactggct cgtcgacttc
    29401 acctgtttcg tgctggccgt cgtcctcggc ctggtggtgg ccgacacgct caccgagcag
    29461 gagaacctcc cgcactccct cgtcgtcgcc gaccagctgc tgggcgcgct ggcctgcgcc
    29521 gccgtgtggc tgcgccgtcg ctggcccttc ggcctcgccg ccgcgacgat ccccctcgcc
    29581 ttcctctcca cgacctcggc cggcgcctgc acgatcgccc tcttcaccct cgccgtgcac
    29641 cggcccttcc ggtacgtcgc ctgggtcggc ggtctccagc tcgccgtgat cccgttgctg
    29701 gtgtgggccc gcccggaccc cgacctggag tacgggccgg ccgtggtgtg gaccgtgctg
    29761 atcaccgtcg cggtgatcgg ctggggcatg ctcgtgcggt ccaggcggca gctcatgctg
    29821 agcctgcgcg accgggctcg gcgcgcggag acggaggccc ggctgcgggc cgagcaggcg
    29881 cagcggctgg cccgtgaggc catcgcccgg gagatgcacg acgtgctggc ccaccggctc
    29941 accctgctca gcgtgcacgc cggcgcgctg gagttccggc cggacgcgcc ccgcgaggag
    30001 atcgtgcgcg cggccggggt catccgggag agcgcccacg aggccctcca ggacctgcgg
    30061 gagatcatcg gtgtgctcag ggccggcgaa cacgacgacg cgggccgacc gcagccgacc
    30121 ctggccgccc tggacgcgct ggtcgccgag tcccgcgagg cgggcatgaa ggtcaccctc
    30181 gaccagcgcg tcagcgaccc gggtgccgtg cccgcctccg tcggccgcac cgcctaccgc
    30241 atcacccagg agtgcctcac caacacccgc aagcacgcgc cgggcgcgga ggccgccgtc
    30301 gtggtggccg gcgctcccgg agagggcctc acggtgaccg tccgcaaccc cgccccggag
    30361 ggcgacgtcc cgcccgtccc cggctccggc cagggcctga tcggcctcac cgaacgcgcg
    30421 gccctcaccg gcggccgcct ggagcacggg ccgcgggagg acggcggctt cgaggtacgg
    30481 gcctggctgc cgtggcccct gaccacgtga cggcggccac ggcgaccgcc gattgccgat
    30541 tgccgattgc cgactgccga tcgccgatcg ccgatggcca actccccggc gccgagcgtg
    30601 attacgtggg gcccatgact gcgatcagac tcctcctcgt cgacgacgac cccctggtac
    30661 gagccggtct gtccctcatg atgggcggcg ccgaggacat cgagatcgtc ggtgaggccg
    30721 ccgacggcgg cgaggtcgag gcgctggtcg agcgcacccg ccccgacgtc gtcctgatgg
    30781 acatccggat gccgtcggtg gacggcctga ccgccacccg gcggctgcgt gcccgcgagg
    30841 acgccccaca ggtcgtcgtc ctcaccacct tccacgccga cgagcacgtg ctgcgcgccc
    30901 tgcgcgcggg tgccgccggg ttcgtcctca aggacacccc gcccgcccgg atcgtcgagg
    30961 cggtacgccg ggtcgcggcc ggcgaccccg tcctgtcgcc caccgtcacc cgccagttga
    31021 tggcccacgt ggccggcacc gccgccgacg accgccgggc acgcgcgcgt gcccggatcg
    31081 ccgtcctggg cgaacgggaa cgcgaggtca cggtcgccgt cgggcgcggc ctgtccaacg
    31141 ccgagatcgc cgccgcactg ttcatgagtg tcgccaccgt caagacccac gtctcccgtg
    31201 tcctggccaa gctcgacctc aacaaccggg tgcagatcgc cctgctggcg tacgacgcgg
    31261 gactgctgga ggacgaggac tgaacccccg atccgcccgg cggagcgggc actcgggggc
    31321 cgccccggcc gttggagcgg tgacggggag gggacggcat gacggtggag acgatcgacc
    31381 tggcggagtt cggcgagggg ttccgacgcg acccgcatcc ggtgtacgcg catctcaggc
    31441 ggcgcggccc gatccacaag gtg
//
