LOCUS       NZ_CP099468            21053 bp    DNA     linear   CON 04-JUL-2024
DEFINITION  Streptomyces phaeoluteigriseus strain Qhu-M197 chromosome, complete
            genome.
ACCESSION   NZ_CP099468
VERSION     NZ_CP099468.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces phaeoluteigriseus
  ORGANISM  Streptomyces phaeoluteigriseus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1  (bases 1 to 9026270)
  AUTHORS   Zhang,B., Xiang,X. and Fan,J.
  TITLE     Complete genome sequence of soil microorganisms Streptomyces sp.
            Qhu-M197 isolated from Alpine meadows habitats on the Tibetan
            Plateau
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9026270)
  AUTHORS   Zhang,B., Xiang,X. and Fan,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2022) Faculty of Eco-Environmental Engineering,
            qinghaiuniversity, No. 251 Ningda Road, Chengbei District, Xining
            City, Qinghai Province 810000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Hifiasm v. v0.14; Circlator v. v1.5.5; Pilon v.
            v1.22
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 68.51291x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023923245.1-RS_2024_07_04
            Annotation Date                   :: 07/04/2024 06:06:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,100
            CDSs (total)                      :: 8,006
            Genes (coding)                    :: 7,707
            CDSs (with protein)               :: 7,707
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 299
            CDSs (without protein)            :: 299
            Pseudo Genes (ambiguous residues) :: 0 of 299
            Pseudo Genes (frameshifted)       :: 130 of 299
            Pseudo Genes (incomplete)         :: 241 of 299
            Pseudo Genes (internal stop)      :: 34 of 299
            Pseudo Genes (multiple problems)  :: 90 of 299
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:40:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1320245
            Orig. end                         :: 1341298
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP099468.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11053](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11053
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(1140..1156)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.58"
                     /tool="antismash"
     gene            complement(1234..1956)
                     /locus_tag="NFX46_RS06070"
                     /old_locus_tag="NFX46_06070"
     CDS             complement(1234..1956)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992842.1"
                     /locus_tag="NFX46_RS06070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06070"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_073491328.1"
                     /transl_table=11
                     /translation="MDSTAATALPDLWDRLVGTQSDPDLWVVIATMAAALAVVVPHTLW
                     RLSRNAITIAHEGGHGLVALLTGRQLTGIRLHSDTSGLTLSRGKPHGLGMILTAASGYT
                     APPLLGLGGAALLGAGRITLLLWLATVLLVAMLVMIRNAYGVLTVVVTGGAFLLVSWLA
                     DAQVQAAFAYAVVWFLLLGGVRPAFELQAKRSRGGAGDSDADQLSRLTHVPAGLWLFLF
                     HAVSLCALLGGGRWLLGL"
     gene            2007..2822
                     /locus_tag="NFX46_RS06075"
                     /old_locus_tag="NFX46_06075"
     CDS             2007..2822
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="NFX46_RS06075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06075"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_252546309.1"
                     /transl_table=11
                     /translation="MCGRYAASRQPEDLAGVFEIERWEPEETLEPDYNVAPTKEVHVVL
                     DRPLKDVPDPRPVRQLRKLRWGLVPSWSKTPEGAARMINARAETVHEKPSFRRAFATRR
                     CVIPADGYYEWVTGQQERELEVEGRRKRPRKQPYFVLPADGSVFAMAGLYEFWRDRTLP
                     DDHPRAWWATCSVVTTDAETTPLAGSPAEGPRTLYDIHPRMPLMLTRDRWDAWLDPSRT
                     DVEDLRSLLAPPPPGLMRAYPVSTAVSNVRNNGPELLKELEGPEEGTLF"
     gene            2974..3561
                     /locus_tag="NFX46_RS06080"
                     /old_locus_tag="NFX46_06080"
     CDS             2974..3561
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119817.1"
                     /locus_tag="NFX46_RS06080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06080"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_252556199.1"
                     /transl_table=11
                     /translation="MTWHRARRPRLVLAVSHGAGGGIEARDLRALAEVLPGHGVSVALV
                     EQPWRVAGGKVAPAPKTLDVGWRGIWPAVAKAGLPVISGGRSAGARVACRTAVELGAHA
                     VLALSFPLHPPGRPERSRAAELLGAGVPTLVVQGGNDPFGKPAEFPEGTYALVEVPYGD
                     HGFAVPKRAPVTQDQALETVTAAVLPWAVSLG"
     gene            3810..4505
                     /gene="sigR"
                     /locus_tag="NFX46_RS06085"
                     /old_locus_tag="NFX46_06085"
     CDS             3810..4505
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="NFX46_RS06085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06085"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_211363006.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTDNGQAELPEGQGTGVGTAAESTTERSARFERDAL
                     EFLDQMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINS
                     YRKKQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKAALQAIPEEF
                     RIAVYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGAGE
                     SNEAKGSGS"
     gene            4502..4804
                     /gene="rsrA"
                     /locus_tag="NFX46_RS06090"
                     /old_locus_tag="NFX46_06090"
     CDS             4502..4804
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136687.1"
                     /locus_tag="NFX46_RS06090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06090"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_073491330.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCGEVLDHLYEFLDSEMPDMDRDKFKQHFNECSPCL
                     EKYGLEEAVKKLVKRCCGHDDVPTDLRSKVMGRIELIRSGQAVPEHDVSVTPQES"
     gene            5029..6339
                     /locus_tag="NFX46_RS06095"
                     /old_locus_tag="NFX46_06095"
     CDS             5029..6339
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657918.1"
                     /locus_tag="NFX46_RS06095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06095"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_252546312.1"
                     /transl_table=11
                     /translation="MDGIPVRARVYVGCAVLGALCCLFPLPSDRTHWWPVLLLAALYAG
                     GERVARRRFAGTLYPVLLAGAFLFPAAAAALVPLPGALLSPVEHRPFPLRRVWRAARLA
                     LGVWAASRAHEALGGREAVGASDGPALLLPAAAGVLVLCLVLAVLDGGILALAEGLPAR
                     RAWHGPFLRSLAPVGVHGLAGLMMAVLWHSPYGPVAALLVLFPMGVSWWVFAQYHRERA
                     AHQATIRALVQAVDIKDGYTRGHSERVGQASLLIARELGMDEGRVEVIRFAGILHDVGK
                     LGVPTRLLRKNGPLTPEERRVIELHPEYGHEITRGISFLGEARSAILHHHERLDGSGYP
                     YGLVGSQIPEPARVVAVADAFDAMTSTRSYSRARPVPVALEELQRCAGAHFDPRMVTAL
                     TRVITRDGWHPIVTADEPRLPAQSPADPVPERPGARR"
     gene            6336..7595
                     /locus_tag="NFX46_RS06100"
                     /old_locus_tag="NFX46_06100"
     CDS             6336..7595
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018845561.1"
                     /locus_tag="NFX46_RS06100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06100"
                     /product="HD domain-containing protein"
                     /protein_id="WP_252546314.1"
                     /transl_table=11
                     /translation="MSGRRRAAWAGGLLSVLHGAAGLLVVASLFVVLRSGLAERPVALA
                     FGVLMAVGELTRWSGPGLREAAPLGSAASLSYALLGEHAGHATHHGVAQVVAVVVAASL
                     LGSVPHIARGQGPVLDHLVRRVLAVGFAAVCFQPLYNHGVFAGWTGPAYALLLLALLVL
                     TALCDAVVAAALAHSRTGWPFAPLLRDELRSVPGLGSAVAATGAVMALAVAVVGLWALP
                     VFSVPLLLTQLSLRRYAAVRATYRQTIASLARATEIAGYTPAGHARRVAALSQAVGRDL
                     GLTEPELTVLEYAALMHDIGQLSLVDPVPAGATAGLPPAEQRRIALLGGAVVRQTGASA
                     QVAAVVECQADPYPEQPTAARIVRVVNAYEEKVRDAGPGGPLTALEELRLGTGGEYAPE
                     VVEALARVLSRDCLTLPAGG"
     gene            7701..8681
                     /locus_tag="NFX46_RS06105"
                     /old_locus_tag="NFX46_06105"
     CDS             7701..8681
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="NFX46_RS06105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06105"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_094103951.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARTAGLRAVALLDRETGAPDWWNVGIAATALQDWPLA
                     RRSWQAYGLHVPGGPTAAGEPLGMDLGSAAVRLSPEGEAEVVWGRRLDPARIEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTSVGHSYPVFDEIELWAPSPVPTWVVLLEAATETDRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGDGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGVAAPASLVRGLLDGWVADSPDSRDWRDLEEVC"
     gene            9020..9670
                     /gene="def"
                     /locus_tag="NFX46_RS06110"
                     /old_locus_tag="NFX46_06110"
     CDS             9020..9670
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="NFX46_RS06110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06110"
                     /product="peptide deformylase"
                     /protein_id="WP_252546317.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHAGVLPVDDEGFVIDTGETEEREQAWRRAGTARPIT
                     VVGNPVLHKECKDVTEFGEELQQLVADMFASQHAAEGVGLAANQIGVDLKVFVYDCPDD
                     EGARHTGVVCNPKLVELPTERRRLDDSNEGCLSVPTAYAPLARPDYAEVTGQDEKGNPV
                     RVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAENEPRYAVVPND"
     gene            10001..11053
                     /gene="cyc1"
                     /locus_tag="NFX46_RS06115"
                     /old_locus_tag="NFX46_06115"
     CDS             10001..11053
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009307568.1"
                     /locus_tag="NFX46_RS06115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06115"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_353850221.1"
                     /sec_met_domain="T1TS (E-value: 1.1e-60, bitscore: 205.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVAVPASLSLPVIEAVFPRQLHPYWPQLQENTRAWLLEKRLMP
                     ADKVAEYADGLCYTDLMAGYYLGAPDEVMQAIADYSAWFFVWDDRHDRDVVHGRAAAWR
                     QLRRRLHVALDSPDEYLQHEDPLVAGLADSVGRLYSFLPATWSERFARHFHEVIEAYDR
                     EFHNRMDGRIPGVEEYLALRRLTFAHWIWTDLLEPSAGCELPDAVRKHPAYRRAALLSQ
                     EFAAWYNDLCSLPKEIAGDEVHNLGISLIAHEGLTLEEAVEEIRRRVEDCISEFLVTEQ
                     DVLRLADRLTDGTVHGKELGAAVRACLENMRNWFSSVYWFHHESGRYMVDSWDDRSTPP
                     YVNNEAAGEK"
     gene            11050..12420
                     /locus_tag="NFX46_RS06120"
                     /old_locus_tag="NFX46_06120"
     CDS             11050..12420
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326965.1"
                     /locus_tag="NFX46_RS06120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06120"
                     /product="cytochrome P450"
                     /protein_id="WP_252546323.1"
                     /sec_met_domain="p450 (E-value: 2e-66, bitscore: 223.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVNPVTPVASELREPPLAGGGVPLLGHGWKLARDPLAFMSQ
                     LRDHGDIVRIKLGPKTVYAVTTPALTGAMALSPDYIIAGPLWESLEGLLGKEGVATANG
                     PLHRRQRRTIQPAFRLDAIPAYGPIMEEETRALVERWQGGETIDCTSESFRIAVRVAAR
                     CLLRGQFMDERAERLCIALASVFQGMYHRMVVPLGPLYRLPLPANREFNRALADLHLLV
                     DEIVAERRASGQKPDDLLTALLEAKDDNGDPIGEQEIHDQVVAILTPGSETIASTIMSL
                     LLVLADHPEQADKVCSEVRTVTGGRPVAFDDVRKLTHTNNVVIEAMRLRPAVWILTRRA
                     VADTELGGYRIPAGADIVYSPYAIQRDPRSYERHLEFDPDRWLPERSKDIPKYAMRPFS
                     VGNRKCPSDHFSMALLTLVTAVLADGFRFEQVPGSVDETRVGITLRPQRLRLKPVPR"
     misc_feature    11701..11703
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12401..13411)
                     /locus_tag="NFX46_RS06125"
                     /old_locus_tag="NFX46_06125"
     CDS             complement(12401..13411)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544423.1"
                     /locus_tag="NFX46_RS06125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06125"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_252546326.1"
                     /transl_table=11
                     /translation="MLKNVAAILLDGVHPFELGVVCEVFGIDRSDEGLPVYDFAVASAE
                     GPTLSTPHPGFTMSTSHGLERLESADLIAVPAGDTYTAREFPPELLDALRRAVERGTRV
                     LSVCSGAFVLAAAGLLDGRRCAVHWRHAEQLAREYPRTTVEPDVLYVDEDPVITSAGTA
                     AGIDACLHLVRKEQGPEVANGIARRMVVPPHRDGGQAQYIQRPLPRSSCDTVGEVLAWM
                     EQHLDQEVTVEQLAARAHMAPRTFARRFQQETGTTPYRWLLRQRVLVAQHLLEASDETV
                     DAIAWRTGFGTAGALRHQFVRVLDTTPNAYRRTFRGPEAAWTHAGSGDGLTAGRA"
     gene            complement(13623..14636)
                     /locus_tag="NFX46_RS06130"
                     /old_locus_tag="NFX46_06130"
     CDS             complement(13623..14636)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657910.1"
                     /locus_tag="NFX46_RS06130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06130"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_073491337.1"
                     /transl_table=11
                     /translation="MTTRNQNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEVDLH
                     SDVTDLAKLTPAEQHLIGRLVAFFATGDSIVSNNLVLTLYKHINSPEARLYLSRQLFEE
                     AVHVQFYLTLLDTYLPDPEDRAAAFDAVESIPSIREKAEFCFRWMDSVEKLDRLESMSD
                     RRRFLLNLICFAACIEGLFFYGAFAYVYWFRGRGLLHGLATGTNWVFRDETMHMSFAFE
                     VVDTVRKEEPELFDDRLQEQVTDMLREAVEAELQFARDLCGDGLPGMNTDSMRQYLECV
                     ADQRLSRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLDEDF"
     gene            complement(14636..17005)
                     /locus_tag="NFX46_RS06135"
                     /old_locus_tag="NFX46_06135"
     CDS             complement(14636..17005)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378224.1"
                     /locus_tag="NFX46_RS06135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06135"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_252546329.1"
                     /transl_table=11
                     /translation="MTIAPAEPVSAAPKTDGPGTALLRTLTELTADLPDADPGRVAAGA
                     LRGRSARADESELRELATEAAAGLISEDPAYSQLAARLLTIGIRAEAASQGVTTFTESV
                     AVGHREGLIADRTAEFVRLHAARLDALVDTGADDRFGYFGLRTLHSRYLLRHPITRKVV
                     ETPQHFLLRVASGLAEDDTTRSVDEVAALYTLMSRLDYLPSSPTLFNSGTRHPQMSSCY
                     LLDSPLDELDSIYDRYQQVARLSKHAGGIGLSYSRIRSRGSLIRGTNGHSNGIVPFLKT
                     LDASVAAVNQGGRRKGAAAVYLETWHSDIEEFLELRDNTGEDARRTHNLNLAHWVPDEF
                     MRRVDDDGQWSLFSPADVPELVDLWGAEFDAAYRAAEAEGLARKTIPARDLYGRMMRTL
                     AQTGNGWMTFKDAANRTANQTAEPGHVVHSSNLCTEILEVTDDGETAVCNLGSVNLGAF
                     VDTDPGATEVIDWERLDETVRTAVTFLDRVVDINFYPTEQAGRSNSRWRPVGLGAMGLQ
                     DVFFKLRLPFDSPEAKALSTRIAERIMLAAYEASAELAERNGPLPAWEKTRTARGVLHP
                     DHYGVEFTWPERWAALRERIAATGLRNSLLLAIAPTATIASIAGVYECIEPQVSNLFKR
                     ETLSGEFLQVNSYLVRELKELGVWDARTREALREASGSVQGFTWIPEDVRALYRTAWEI
                     PQRGLIDMAAARTPYLDQAQSLNLFLETPTIGKLSSMYAYAWKSGLKTTYYLRSRPATR
                     IARAAQAQAPIPVRQPAPEEAVACSLENPESCEACQ"
     regulatory      complement(17127..17270)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(17253..17266)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     misc_feature    complement(17260..17274)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(17291..17305)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.12"
                     /tool="antismash"
     gene            complement(17444..19072)
                     /gene="mctP"
                     /locus_tag="NFX46_RS06140"
                     /old_locus_tag="NFX46_06140"
     CDS             complement(17444..19072)
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006848 - pyruvate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mctP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="NFX46_RS06140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06140"
                     /product="monocarboxylate uptake permease MctP"
                     /protein_id="WP_252546331.1"
                     /transl_table=11
                     /translation="MNGGVNGVALAVFIFFFLAVTVMGFLAARWRRADDEHSLDEWGLG
                     GRSFGTWVTWFLLGGDLYTAYTFVAVPAAIYAAGAAGFFAVPYTILVYPLIFTFLPRLW
                     SVSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGG
                     EDTNWFVKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGG
                     FDDIFAKAGDAFSQTNPATGAPRGSLVPSEAGQWTYATLALGSALALFMYPHSITATLS
                     SRSRDVIRRNTTILPLYSLMLGLLALLGFMAIAAGVKVSNGQLAIPQLFEDMFPDWFAG
                     VAFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPREETRVSKLVSLLVKVGAL
                     AFVLTMDKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLAGWAVGMVYGTVAAY
                     GVASPTQKHFGGSSKEIPGIGEIGYIGLTAFVLNVVVTVVLTFVMRALKAPEGVDETSP
                     SDYTADAGDPGVQVELPPATAGAGH"
     gene            complement(19069..19335)
                     /locus_tag="NFX46_RS06145"
                     /old_locus_tag="NFX46_06145"
     CDS             complement(19069..19335)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925869.1"
                     /locus_tag="NFX46_RS06145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06145"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_252546334.1"
                     /transl_table=11
                     /translation="MSQAPEVNGGPVVTPLRVVIALCLFAPFVAMLWVGSYAKTDPAFI
                     GIPFFYWYQMLWVLLSTMLTVVAYKLWQVDQRGRRNQGGGAAK"
     misc_feature    complement(19404..19418)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.75"
                     /tool="antismash"
     gene            complement(19465..20229)
                     /locus_tag="NFX46_RS06150"
                     /old_locus_tag="NFX46_06150"
     CDS             complement(19465..20229)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="NFX46_RS06150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NFX46_06150"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_252546337.1"
                     /transl_table=11
                     /translation="MSTDVSSAENEGGATVRTARVPKYYRLKKHLLDMTETQSPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDIGYITADDRLAGLLDITAGGRVLRIERLRMANGEPMAIETTHLSAKRF
                     PALRRSLVKYTSLYTALAEVYGVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SVDREGLPVEWVRSVYRGDRYKFVARLKRPVE"
     misc_feature    20376..20391
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 21.11"
                     /tool="antismash"
     misc_feature    20377..20393
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.31"
                     /tool="antismash"
     misc_feature    complement(20547..20562)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.29"
                     /tool="antismash"
ORIGIN
        1 gcaggccgtc ggcggtctcg gtgacgtcgc cgcccagctc gttgatctcc ttggtgaggg
       61 cggccaggcg gtcggtctcg tgcaggcgca ggtgcgagac gccccgcagg gtggaggggg
      121 agtcggcgag ggcggcgacc gccgcgatgc ccggggtcag ctcgccgacg tcgctcaggt
      181 cgacgtcgat gccgtggatc gtgcccgacc cggtgaagac gaggccgtac tcggtcagtt
      241 cgcaggaacc gcccatctcg gtgaagatct cccgcagccg gtcccccggt tgggtggtcc
      301 tggccggcca gtcggggacg acgatccggc cgccggtgac gagtgccgcc gcgaggaacg
      361 gctgcgcgtt ggacaggtcc ggctcgatgg tcaggtcccg gccgagcagc gcgcccggcg
      421 tgacccgcca gacgttcggc tcgccgcccg actccggggt gtccacctgg gcgcccaccg
      481 cgcgcagcat gtccaccgtc atccggatgt gcggcaggga gggcagcgtg gcgccggtgt
      541 gccggacctc gacgccctgg ttgaagcggg ggcccgacag cagcagggcg ctgacgaact
      601 gcgacgagga cgaggcgtcg acctccaccg ggccgccgtc cagcgcgcca ccgccgtgca
      661 ccgtcagcgg cagcgcgccc cggccgtcgt cgtcgatgcg ggcaccgagc acgcgcaggg
      721 cgtcgacgac gccggtcagg ggacgttcgt acgaacgtgg gtcgccgtcg aagcggacgg
      781 gaccgtcggc gagggcggcg accggcggca ggaagcgcat caccgtgccc gcgttgccga
      841 cgtcgacggt ggccgggccg cggagccccg tgggcagcac gcgccaggcc tcgccggtcc
      901 cgtcgggccc cacaccctcc tcgatgccca cccccatctc gcgcagggcg cccgccatca
      961 gcagggtgtc gcgggagcgg agggggcggc gcagccagcc gggctcggag gccagggagg
     1021 ccaggacgag agcgcggttc gtgaccgact tggaccccgg cacgtggacc gtcgcgtcga
     1081 cggcctcgct cgcgtgcggg gcgggccaaa gggcggtgtg ggcggggttc ggggccatag
     1141 gcccactgta taagcagggc atgggcgggg tggtccggcg tgggggccgg ccgggggtcc
     1201 gcgggcggcc cggccggccg ggtccgccgg cgttcagagc cccagcagcc agcgcccgcc
     1261 gcccagcagg gcgcacaggc tcaccgcgtg gaagaggaac agccacaggc ccgccgggac
     1321 gtgggtcagg cgggacagct ggtccgcgtc cgagtcgccg gcgccgccgc gggaccgctt
     1381 cgcctggagt tcgaaggccg ggcgcactcc gccgagcagc aggaaccaca ccaccgcgta
     1441 cgcgaacgcc gcctgcacct gggcatcggc cagccaggac accagcagga aggcgccgcc
     1501 ggtgacgacc accgtcagca ccccgtacgc gttgcggatc atcaccagca tcgcgaccag
     1561 cagcaccgtg gccagccaca gcagcagcgt gatgcggccg gcgccgagca gtgccgcgcc
     1621 gcccaggccc agcagcgggg gagcggtgta gccggaggcc gcggtgagga tcatgccgag
     1681 gccgtgcggc ttgccccggc tgagggtcag gccgctggtg tcggagtgca ggcgtatgcc
     1741 ggtcagctga cggccggtga gcagggcgac cagcccgtga ccgccctcgt gggcgatggt
     1801 gatggcgttg cgcgagaggc gccagagggt gtgcggcacg accacggcga gcgcggcggc
     1861 catggtggcg atcaccaccc acagatcggg gtcggactgg gtgccgacga gccggtccca
     1921 gaggtcgggc agcgcggtgg cggcggtgct gtccatggtt tccggtggct ccctcttgtc
     1981 ctaaggaatc tggcagtgtg gcacgtatgt gcggacggta tgcggcgagt cgccagcccg
     2041 aggatctcgc aggagtcttt gaaatcgaga ggtgggagcc cgaggagacc ctcgagcccg
     2101 actacaacgt ggcccccacc aaggaggtcc atgtggtcct ggaccgtcct ctgaaggacg
     2161 tgccggaccc gcgcccggtt cgccagctgc gcaaactcag gtgggggctg gtcccgtcct
     2221 ggtcgaagac ccccgagggc gccgcccgga tgatcaacgc gcgggcggag accgtccacg
     2281 agaagccgtc gttccgccgc gccttcgcca cccgccgctg cgtcatcccc gccgacggct
     2341 actacgagtg ggtgaccgga cagcaggagc gcgaactgga ggtcgagggg aggcggaagc
     2401 ggccccgcaa gcagccctac ttcgtgctcc ccgccgacgg ctcggtcttc gcgatggccg
     2461 ggctgtacga gttctggcgc gaccgcacgc tgccggacga ccatccgcgg gcctggtggg
     2521 cgacctgctc ggtggtcacc accgacgcgg agacgacccc gctggccggg tcccccgcgg
     2581 agggcccgcg cacgctgtac gacatccacc cccggatgcc cctgatgctc acccgcgacc
     2641 gctgggacgc ctggctggac ccgtcccgca cggacgtcga ggacctgcgt tccctgctcg
     2701 ccccgccccc gcccggcctg atgcgcgcgt accccgtgtc cacggccgtg agcaacgtcc
     2761 gcaacaacgg cccggaactg ctgaaggagc tggagggacc cgaggagggc acactcttct
     2821 gacgtgaccg aggggacgaa ggtgacagac gtgactaccg agccacccga gaacgacgga
     2881 agccccgaga acgacgggag ccctgggaac gacggaagta ccgagaacac cccgaacgcc
     2941 gagaccgtcg acaccgacgc cggtcccgcc cgcatcacct ggcaccgggc gaggcggccc
     3001 aggctcgtcc tcgccgtgag ccacggcgcg ggcggcggca tcgaggcgcg ggatctgcgc
     3061 gcgctcgccg aggtgctccc cgggcacggc gtcagcgtcg ccctcgtcga gcagccctgg
     3121 cgggtggccg gcgggaaggt ggcgcccgcg ccgaagacgc tcgacgtcgg ctggcgcggg
     3181 atctggccgg ccgtcgcgaa ggccggcctc ccggtgatct ccggcgggcg cagcgcgggc
     3241 gcgcgggtgg cctgccgtac cgccgtcgaa ctcggcgccc acgccgtcct cgcgctcagc
     3301 ttcccgctcc acccgcccgg caggcccgag aggtcccggg ccgcggaact gctgggcgcc
     3361 ggggtgccca cgctcgtcgt ccagggcggc aacgacccct tcggcaagcc cgcggagttc
     3421 cccgagggga cgtacgccct ggtcgaggtg ccctacggcg atcacgggtt cgccgtgccc
     3481 aagcgggccc cggtcaccca ggaccaggcc ctggagacgg tcaccgcggc ggtcctcccg
     3541 tgggccgtgt cactcgggtg aacagcgggg aatgttgcgg ggcgcagggc tgttgagcgg
     3601 ggcagaagtg ctgaacacgc agcaccgatg tcgtgggaga ggaagtccgg cgcatgggtt
     3661 cgaccatctg ccccagccgc accgacctgg actggacggt gctgcacgcg gccaagaccg
     3721 ctcacattcg agcggcgggt gggacgggta gtcgtctatc ctccgattcg agtgggaccg
     3781 gtctcggtcc tgcccgcgat cttgaggagg tgggtccggt caccggtacc gacgcaggga
     3841 ccgacaacgg ccaggcggag ctgcccgagg gccagggcac gggtgtgggg acggcagcgg
     3901 agtccaccac ggagcgcagc gcgcgcttcg agcgggacgc gctcgagttc ctcgaccaga
     3961 tgtactcggc ggccctgcgc atgacgcgca acccggcgga cgccgaggac ctggtgcagg
     4021 agacctacgc caaggcgtac gcgtccttcc accagttccg cgagggcacc aatctcaagg
     4081 cctggctgta ccggatcctg accaacacct tcatcaactc gtaccgcaag aagcagcgcg
     4141 aaccccagcg cagcgcggcc gaggagatcg aggactggca gctggcgcgc gccgagtcgc
     4201 acatgtccac gggtctgcgc tccgccgagt cgcaggcact ggaccatctg cccgactcgg
     4261 acgtgaaggc ggcccttcag gcgatccccg aggaattccg catcgccgtc tacctcgcgg
     4321 acgtagaggg ctttgcgtac aaggagatcg cggacatcat ggggacaccc atcggtacgg
     4381 tgatgtcccg gctgcaccgg ggccgccgtc aactgcgcgg catgctcgag gactacgccc
     4441 gtgagcgcgg gctggttccg gcaggcgccg gggagtcgaa cgaagcgaaa ggctctgggt
     4501 catgagctgt ggagagccgc acgagacgga ctgcggtgag gtcctcgacc atctctacga
     4561 gtttctcgac agtgagatgc cggacatgga ccgcgacaag ttcaagcagc acttcaacga
     4621 gtgctcgccg tgcctggaga agtacgggct ggaagaggcc gtcaagaagc tggtcaagcg
     4681 ctgctgcggc catgacgacg tgccgaccga cctgcgctcg aaggtcatgg gccggatcga
     4741 gctgatccgc tccggccagg ccgtgcccga gcacgatgtg tcggtcaccc ctcaggagtc
     4801 ctgacctccg ccctgcctcc gcggaagtcc tgcacccgca gaggtcctgc tgcaccccag
     4861 aggtcctgct gcaccagcgg aagtcctgca cccgcggagg tcccacgtct cccgaggacg
     4921 caccgacatc acccgaatgt gctaatccgc cggtgatacg cccgtgtcgc caccccccgc
     4981 caccctaggc tccggagcct ggacgaggcg tggccggggg agggcgacat ggacggcatt
     5041 ccggtacggg cacgggtgta cgtcggctgt gccgtcctcg gcgccctgtg ctgcctgttc
     5101 cccctgccgt cggaccgcac gcactggtgg ccggtcctac tgctcgccgc gctgtacgcg
     5161 ggcggtgagc gcgtcgcccg ccgccggttc gccggcaccc tctaccccgt cctgctggcc
     5221 ggggcttttc tctttccggc tgccgccgcc gcgctcgtcc cgctgccggg cgcgctgctg
     5281 tccccggtgg agcaccgccc cttcccgctg cggcgcgtct ggcgggccgc ccggctggcg
     5341 ctcggcgtgt gggccgcgtc ccgcgcgcac gaggcgctgg gcggccggga ggccgtcggg
     5401 gcgtccgacg gccccgccct cctcctcccg gccgcggccg gcgtccttgt cctctgcctg
     5461 gtgctcgccg tcctggacgg cgggatcctc gcgctggccg aggggctgcc ggcgcggcgc
     5521 gcctggcacg ggccgttcct gcgctccctg gcacccgtag gggtgcacgg gctcgccggg
     5581 ctgatgatgg ccgtcctgtg gcacagcccc tacgggccgg tcgccgcgct gctcgtactg
     5641 ttcccgatgg gtgtgtcctg gtgggtgttc gcccagtacc accgggagcg cgccgcccac
     5701 caggcgacga tccgcgcgct ggtgcaggcc gtcgacatca aggacggcta cacccgcggg
     5761 cacagcgaac gcgtcggcca ggcctccctg ctgatcgccc gtgagctggg catggacgag
     5821 ggccgggtcg aggtgatccg cttcgccggg atcctgcacg acgtcggcaa gctcggcgtg
     5881 cccacccggc tgctccgcaa gaacggcccg ctgacgcccg aggaacggcg cgtgatcgaa
     5941 ctgcaccccg agtacgggca cgagatcacc cggggcatct ccttcctcgg cgaggcccgc
     6001 tcggcgatcc tccaccacca cgagcggctg gacggcagcg gctaccccta cgggctggtc
     6061 ggcagccaga tcccggaacc cgcgcgcgtg gtggcggtcg ccgacgcctt cgacgcgatg
     6121 acctcgaccc gctcctacag ccgggcccgc cccgtgccgg tggcgctgga ggaactccag
     6181 cggtgcgcgg gggcccactt cgacccccgc atggtcaccg cgctgacccg cgtgatcacg
     6241 cgggacggct ggcacccgat cgtcaccgcc gacgagcccc gcctgccggc gcagtccccg
     6301 gccgaccccg ttcccgagcg gccgggggcc cggcggtgag tggccgccgc agggcggcgt
     6361 gggcaggcgg gctcctgagc gtcctgcacg gcgccgccgg gctgctcgtc gtcgcgtcgc
     6421 tgttcgtcgt cctccgctcg gggctggcgg agcggcccgt cgcgctcgcc ttcggggtgc
     6481 tgatggccgt cggcgagctg acccggtgga gcggacccgg actgcgcgag gccgcgccgc
     6541 tcggttccgc cgcctcgctg tcgtacgcgc tgctcgggga gcatgccggg cacgccacgc
     6601 accacggggt ggcccaggtc gtcgccgtcg tggtggccgc ctcgctgctc ggcagcgtgc
     6661 cgcacatcgc gcgcgggcag gggcccgtcc tggaccacct ggtccggcgc gtgctggccg
     6721 tcggcttcgc cgccgtctgc ttccagccgc tctacaacca cggggtgttc gccggctgga
     6781 ccggcccggc ctacgcgctg ctgctgctcg cgctgctcgt gctcaccgcg ctgtgcgacg
     6841 ccgtcgtggc cgccgcgctc gcgcactccc gcaccggctg gccgttcgcc ccgctgctcc
     6901 gcgacgagct gcggtccgta cccgggctcg ggtcggcggt ggccgcgacg ggcgcggtga
     6961 tggcgctggc ggtggccgtc gtcggcctgt gggcgctgcc ggtgttctcg gtgccgctgc
     7021 tgctcaccca gctgtccctg cgccggtacg ccgccgtccg cgccacctac cggcagacca
     7081 tcgcctccct ggcccgcgcc accgagatag ccgggtacac cccggccggg cacgcccgcc
     7141 gggtcgccgc gctcagccag gcggtcggcc gggacctcgg cctcacggag ccggagctga
     7201 ccgtgctgga gtacgcggcc ctgatgcacg acatcgggca gctcagcctc gtcgacccgg
     7261 tcccggccgg ggccacggcc gggctgcccc cggccgagca gcggcgcatc gccctgctcg
     7321 gcggggccgt ggtccgccag accggggcga gtgcgcaggt cgccgcggtg gtggagtgcc
     7381 aggccgaccc ctacccggag cagccgacgg ccgcgcggat cgtgcgggtg gtcaacgcct
     7441 acgaggagaa ggtgcgcgac gccggccccg gcgggccgct cacggcgctg gaggaactca
     7501 ggctgggcac gggcggggag tacgcccccg aggtggtgga agccctggcc agggtgctgt
     7561 cgcgggactg tcttaccctg cccgcgggtg ggtaacccat gggtaatgag cgcccttccg
     7621 acgacacgtg gttggatgcg agggagagag tgtccggggg cactggccag cccacagaac
     7681 ggaactggca ggcgggaatc gtgaggatct tcggcaaggg acggcaccgg ccctccgcct
     7741 cctggcggca ggccaccgat cgcgccttca cgctgatcgg cgacggccgg tacgaggacg
     7801 cgggcgcgct gctgacccgt gccgccgatc tcgagccctg gctgtcggag tcctggttca
     7861 acctcgccct gctgcacaag ttccggcacg actgggagca ggcccgcacc gccgggctcc
     7921 gggcggtcgc cctgctcgac cgcgagaccg gcgcccccga ctggtggaac gtcggcatcg
     7981 ccgccaccgc cctgcaggac tggccgctgg cccggcgctc ctggcaggcc tacgggctgc
     8041 acgtcccggg cgggcccacc gccgccggcg agcccctcgg catggatctg ggcagcgcgg
     8101 ccgtacggct gtcgcccgag ggggaggccg aggtggtgtg ggggcggcgg ctggaccccg
     8161 cgcggataga ggtgctgtcg atcccgctgc cgtcgtccgg gcggcgctgg ggcgaggtcg
     8221 tcctgcacga cggggtgccg cacggcgagc gcaccacctc ggtggggcac tcctaccccg
     8281 tcttcgacga gatcgagctg tgggcgccct cgccggtgcc gacctgggtg gtcctgctgg
     8341 aggcggccac ggagacggac cgtgacgccc tggagcagct ggcggccgac gcgggcttcg
     8401 ccgccgagga ctggtcgtcc tccgtacggc tgctgtgccg gatgtgctcc gagtcgcgga
     8461 tgccgtccga cgagggggac ggcgagcacc tcgaccccca cgatcacagt gagccggggc
     8521 accccgggcc gctcggccac cggaccgacg ggcagctgtg ggtgcccgag cgggagtgcg
     8581 gggtggccgc gccggcttcg ctggtgagag ggctgctgga cgggtgggtc gcggacagcc
     8641 cggactcccg ggactggcga gacctggaag aggtctgcta gagcctgtcg ttcggatcag
     8701 gtcgcaggaa gtcgacagcg ctgttcagtg ccgatgagcg gggtctggtg cgtgcggctg
     8761 cagggcggag gagggcgtcg acgcggagcg tcggcaaccg acgacgacgc ggcggatgcg
     8821 cgtgccggac cccgcgtctg cggcgtgatc caaacgagag accttaggcc ccgtcgctcg
     8881 gctgcgagcc ggtgtgtggc tcgtcgcgcc ccgcggcgga gccgcatgtc gacacggccc
     8941 cgcgcgccgt gcgggacgct ccacgtaccc tgtatccgca tcacaccccc cgtttttctg
     9001 aggaaggcat acgtcggtca tggcgcagca ggacaccgat cagcagcacg cgggagtgct
     9061 ccccgtggac gacgagggct tcgtcatcga caccggggag acggaggagc gcgagcaggc
     9121 ctggcgtcgg gccgggaccg cgcggcccat caccgtcgtg gggaacccgg tgctgcacaa
     9181 ggagtgcaag gacgtcaccg agttcggcga ggagctccag cagctggtcg cggacatgtt
     9241 cgcctcgcag cacgccgccg agggcgtggg cctggccgcc aaccagatcg gcgtcgatct
     9301 gaaggtgttc gtctacgact gcccggacga cgagggcgcc cggcacaccg gagtggtctg
     9361 caaccccaag ctggtggagc tgcccacgga gaggcgccgg ctggacgaca gcaacgaggg
     9421 ctgtctgtcg gtgcccaccg cgtacgcgcc gctggcccgg cccgactacg ccgaggtgac
     9481 cggtcaggac gagaagggca acccggtcag ggtgcgcggc acggggtact tcgctcggtg
     9541 tttgcagcac gagacggatc acctctacgg gtacctctac atcgaccgtc tctccaagcg
     9601 tgaacgcaag gacgcgttgc ggcagatggc cgagaacgag cctcgctacg ccgtggtccc
     9661 caacgactga gccgtcctcc ttcccacgac gcccggcccg cgatcagcgg cggccgggcg
     9721 tcgttcgtgt gtccgacgca cgttcgatcg cttatgcaca tctgctgatc cataacaagt
     9781 cacgcaaggg gggattctcg gcgtgttggg gtagtgaatg aagcaaatcc gttcccagaa
     9841 cggtcagttg tggtgctgaa tgggaagtgc ggggatacgc aacggcgcac gcccggcacg
     9901 gcgggagggg tgtgtaccaa ctggcggctg agaggggttg ttcgtgccag ctttcccata
     9961 cagcaccaca taccgcacca cataccgcac cgcggggacc gtgaccgcgg tcgcggttcc
    10021 cgcatcgctc tctctcccgg tcatcgaggc ggtgtttccc aggcaactgc atccgtattg
    10081 gcctcagttg caggagaaca cgcgtgcgtg gctgctcgaa aagcggctca tgccggcgga
    10141 caaggtcgcg gaatatgccg acggcctgtg ctacaccgac ctgatggcgg gctactacct
    10201 cggcgcaccc gacgaggtca tgcaggccat cgccgactac agcgcgtggt tcttcgtctg
    10261 ggacgaccgg cacgaccgtg acgtcgtgca cggccgggca gccgcctggc ggcagttgcg
    10321 gcgccgcctg cacgtggccc tcgactcccc ggacgagtac ctgcaacacg aggatccgct
    10381 ggtcgccgga ctcgcggaca gtgtgggccg gctgtactcc ttcctccccg cgacctggag
    10441 cgagcggttc gcccgccact tccacgaggt gatcgaggcg tacgaccggg aattccacaa
    10501 ccggatggac gggcgcatac cgggcgtcga ggagtatctg gccctgcgcc ggctcacctt
    10561 cgcgcactgg atctggacgg atctgctgga gccgagtgcg gggtgcgaac tcccggacgc
    10621 cgtacggaaa cacccggcct atcggcgtgc ggctctgctg agtcaggaat tcgccgcctg
    10681 gtacaacgac ctctgttcgc tcccgaagga aatagcgggc gacgaggtgc acaatctcgg
    10741 aatcagtctc atcgcccatg aagggctgac cctcgaagag gcggtcgagg aaatcaggcg
    10801 gcgcgtcgag gactgcatat ccgaattcct cgtcacggag caggacgtgc tgaggctggc
    10861 cgacaggctc accgacggga cggtccacgg aaaggaactc ggcgccgccg tacgggcctg
    10921 tctcgagaac atgaggaact ggttcagttc cgtctactgg ttccaccacg agtccggccg
    10981 ctacatggtc gacagctggg acgaccgttc cacgcccccg tacgtcaaca acgaagcggc
    11041 aggtgagaaa tgaccgtcga gtccgtcaac cccgtgacgc ccgtggcatc ggaactgcgt
    11101 gagccgccac tggccggtgg tggggttccg cttctcggcc acggctggaa gctcgcccgc
    11161 gacccgctgg ccttcatgag ccagctgcgc gaccacggcg acatcgtccg catcaagctc
    11221 ggaccgaaga cggtgtacgc cgtcaccacg ccggccctga ccggggccat ggccctcagc
    11281 cccgactaca tcatcgccgg accgctgtgg gagtccctgg aagggctgct cggcaaggag
    11341 ggcgtggcca ccgccaacgg cccgctccac cggcgccagc ggcgcaccat ccagcccgcg
    11401 ttccggctcg acgccatccc cgcctacggg ccgatcatgg aggaggagac gcgcgcgctc
    11461 gtcgagcggt ggcagggcgg cgagacgatc gactgcacct cggaatcgtt ccggatagcg
    11521 gtgcgggtgg cggcccgctg tctgctgcgc gggcagttca tggacgagcg ggccgagcgg
    11581 ctgtgcatcg cgctcgccag cgtcttccaa ggtatgtacc accggatggt ggtgccgctc
    11641 ggaccgctct acaggctgcc gcttccggcc aaccgcgaat tcaaccgggc cctggccgat
    11701 ttacatctcc tggtcgacga gatcgtcgcc gaacgtcggg catcaggtca aaagccggac
    11761 gatttgctga cggcattgct ggaagcgaag gacgacaatg gcgacccgat cggggaacag
    11821 gagatccacg accaggtcgt cgcgatcctc acccccggca gcgaaaccat cgcttccacg
    11881 atcatgtcgc tgctcctggt tctcgcggac catccggaac aggcggacaa ggtgtgctcc
    11941 gaggtacgga ctgtcaccgg agggcggccc gtcgcattcg acgacgtgcg caagctcacg
    12001 cacacgaaca acgtcgtcat cgaggccatg cgtttgcgcc cggccgtatg gatattgacg
    12061 cggcgggcag tcgccgacac cgaactcggt ggctatcgca ttccggccgg ggccgacatc
    12121 gtgtacagcc cgtacgcgat ccagcgcgac ccgcggtcct acgagcggca cctcgagttc
    12181 gaccccgacc gctggctccc ggagcggtcg aaggacatcc cgaagtacgc gatgcggccg
    12241 ttcagcgtgg gcaaccgcaa gtgccccagc gaccacttct cgatggccct gctcacgctg
    12301 gtcacggcgg tgctcgcgga cggcttccgg ttcgagcagg tccccggctc ggtcgacgag
    12361 acccgggtgg gcatcacgct gcgtccgcaa cggctgcggc tcaagcccgt cccgcggtga
    12421 gaccgtcccc gctgccggcg tgcgtccagg cggcctccgg gccccggaac gtacgccggt
    12481 aggcgttcgg ggtggtgtcc agcacccgca cgaactggtg ccgcagcgcg cccgccgtgc
    12541 cgaacccggt ccgccaggcg atcgcgtcca ccgtctcgtc ggacgcctcc agcagatgct
    12601 gggcgaccag tacccgctgg cgcaggagcc agcggtaggg cgtcgtgccg gtctcctgct
    12661 ggaagcggcg ggcgaaggtg cgcggcgcca tgtgggcgcg ggcggcgagc tgctcgacgg
    12721 tgacctcctg gtcgaggtgc tgctccatcc acgcgagcac ctcgcccacg gtgtcgcagg
    12781 aagagcgcgg cagcggccgc tggatgtact gggcctggcc gccgtcccgg tgcggcggta
    12841 cgaccatccg ccgggcgatc ccgttggcga cctcgggccc ctgctccttg cgcacgaggt
    12901 gcagacaggc gtcgatgccg gcggccgtgc cggccgaggt gatcaccggg tcctcgtcga
    12961 cgtagagcac gtcgggctcg acggtcgtgc gcgggtactc gcgggcgagc tgctccgcgt
    13021 gccgccagtg caccgcgcag cgccgcccgt ccaggagccc cgccgcggcc agcacgaacg
    13081 ccccggagca cacactcagc acccgggtcc cgcgctccac cgcccggcgc agcgcgtcga
    13141 gcagctcggg cgggaactcc cgggccgtgt acgtgtcgcc ggccggtacg gcgatcaggt
    13201 cggcgctctc cagccgttcg agcccgtgtg acgtgctcat cgtgaagccc gggtgcggtg
    13261 tggacagggt cggcccctcg gccgaggcga cggcgaagtc gtagaccggc agcccctcgt
    13321 cgctgcggtc gatgccgaac acctcgcaga cgacaccgag ttcgaaggga tgcacgccgt
    13381 cgaggaggat cgcggccacg ttcttcagca tgccgccagt gtgcaccgga agtggcagta
    13441 atttgaaggt gtgcggcagt cctgccactg tcatgagtgt cacggacgca tgatgcttac
    13501 ctcatgaacg cactcaccga agctctcacg gtcctggtcg tcttcctcgt cctcgcgggt
    13561 ccggcgctcg tggggctggc ccacgaacgc cggatcgacc gccgactgcg cgaggcgcgg
    13621 actcagaagt cctcgtccag gtcgacggtg ccctccaccg cgacctggta cgccgacgga
    13681 cggcgctcga agaagttggt cagctcctga acgccctgca actccatgaa ggagaacggg
    13741 ttctccgagc cgtacaccgg ggcgaaaccg aggcggctca gccgctggtc ggcgacgcac
    13801 tccaggtact ggcgcatcga gtcggtgttc atgcccggca gtccgtcccc gcacaggtcc
    13861 cgcgcgaact gcagctcggc ctcgacggcc tcccgcagca tgtcggtgac ctgctcctgg
    13921 agccggtcgt cgaacagctc cggctcctcc ttgcggacgg tgtcgacgac ctcgaacgcg
    13981 aaggacatgt gcatggtctc gtcacggaac acccagttgg tgccggtggc gaggccgtgc
    14041 agcagacccc ggccgcggaa ccagtagacg tacgcgaagg cgccgtagaa gaacagcccc
    14101 tcgatgcacg cggcgaagca gatcaggttg agcaggaagc ggcggcggtc ggacatcgac
    14161 tccagccggt ccagcttctc caccgagtcc atccagcgga agcagaactc ggccttctcg
    14221 cggatggagg ggatgctctc gaccgcgtcg aaggcggcgg cgcggtcctc cgggtcgggg
    14281 aggtaggtgt ccagcagggt cagatagaac tggacgtgca ccgcctcctc gaagagctgc
    14341 cggctcaggt agagccgcgc ctcgggggag ttgatgtgct tgtacagcgt cagcaccagg
    14401 ttgttcgaga cgatcgagtc gcccgtcgcg aagaacgcga ccagccggcc gatcagatgc
    14461 tgctcggcgg gcgtcagctt cgcgaggtcg gtgacgtccg agtggaggtc gacctcctcg
    14521 acggtccagg tgttcttgat ggcgtcgcgg tagcgctcgt agaagtcggg gtagcgcatg
    14581 ggacgcaggg tcagctcgaa gcccgggtcg aggagattct ggttacgggt ggtcatcact
    14641 ggcaggcctc gcaggactcg gggttctcaa gggagcaggc gacggcctct tcgggagccg
    14701 gctgccgcac ggggatgggg gcttgggcct gggcggcgcg ggcgatgcgg gtcgccgggc
    14761 gcgagcgcag gtagtacgtc gtcttgagcc ccgacttcca ggcgtaggcg tacatcgagg
    14821 agagcttgcc gatggtcggc gtctccagga agaggttcag ggactgcgcc tggtccagat
    14881 acggggtccg cgcggcggcc atgtcgatca ggccgcgctg tgggatctcc cacgccgtgc
    14941 ggtacagcgc ccgtacgtcc tcggggatcc aggtgaaccc ctggaccgag ccgctcgcct
    15001 cgcgcagcgc ctcgcgggtg cgggcgtccc agacgcccag ctccttgagt tcccgcacca
    15061 ggtaggagtt gacctggagg aactcgccgg acagcgtctc gcgcttgaac aggttggaca
    15121 cctgcggctc gatgcactcg tacacaccgg cgatcgacgc gatggtggcg gtcggcgcga
    15181 tggccaggag cagcgagttg cgcaggccgg tcgccgcgat ccgctcgcgc agcgccgccc
    15241 agcgctccgg ccaggtgaac tcgacgccgt agtggtcggg gtgcagcacg ccacgtgccg
    15301 tacgggtctt ctcccaggcg ggcagcgggc cgttgcgctc ggcgagttcc gcggaggcct
    15361 cgtacgcggc gagcatgatc cgctcggcga tccgggtgga gagcgccttg gcctcgggcg
    15421 agtcgaaggg cagccgcagc ttgaagaaga cgtcctggag gcccatcgcg cccagaccga
    15481 ccgggcgcca gcgggagttg gagcggcccg cctgctcggt cggatagaag ttgatgtcga
    15541 cgacccggtc caggaaggtg acggcggtgc ggacggtctc gtccagccgc tcccagtcga
    15601 tgacctcggt ggccccgggg tccgtgtcga cgaacgcgcc gaggttcacc gaccccaggt
    15661 tgcagaccgc cgtctcaccg tcgtcggtga cctccaggat ctccgtgcac aggttcgagg
    15721 agtggaccac atggcccggc tcggcggtct ggttggcggt gcggttggcg gcgtccttga
    15781 aggtcatcca gccgttgccg gtctgcgcga gggtgcgcat catgcggccg tacagatcac
    15841 gcgccgggat ggtcttcctg gccagcccct cggcctccgc cgcgcggtag gccgcgtcga
    15901 actccgcgcc ccacaggtcg accagctcgg gcacgtcggc cggggagaac agggaccact
    15961 gcccgtcgtc gtctacccgg cgcatgaact cgtccggcac ccagtgcgcc aggttgaggt
    16021 tgtgcgtacg gcgggcgtcc tcgccggtgt tgtcgcgcag ctccaggaac tcctcgatgt
    16081 cggagtgcca ggtctccagg tacaccgcgg ccgcgccctt gcgccggccg ccctggttca
    16141 cggcggcgac cgaggcgtcc agggtcttca ggaacggcac gatgccgttg gagtgcccgt
    16201 tggtgccgcg gatgagcgac ccgcgggaac ggatgcggct gtacgacaga ccgatgccgc
    16261 cggcgtgctt ggagaggcgg gcgacctgct ggtagcggtc gtagatggag tccagctcgt
    16321 ccagcgggga gtcgaggagg tagcaggacg acatctgcgg gtggcgggtg ccggagttga
    16381 acagggtggg ggaggagggg aggtagtcca ggcggctcat cagcgtgtag agcgcggcga
    16441 cctcgtcgac ggacctcgtc gtgtcgtcct cggccaggcc gctcgccacg cgcagcagga
    16501 agtgctgggg cgtctcgacg accttgcggg tgatcgggtg gcgcagcagg tagcggctgt
    16561 gcagggtgcg caggccgaag tagccgaagc gatcgtcggc gcccgtgtcg accagcgcgt
    16621 cgagccgggc cgcgtgcagc cggacgaact cggcggtgcg atcggcgatc aggccctcgc
    16681 ggtggccgac ggcgacggac tcggtgaagg tggtgacgcc ctgggaggcg gcctccgcgc
    16741 ggatcccgat cgtgagcagc cgggcggcca gttgggagta ggcgggatcc tcggagatca
    16801 gaccggcggc cgcctcggtg gccagctcgc gcagctccga ctcgtccgcc cgcgcggacc
    16861 ggccccgcag ggcgccggcg gcgacccggc cggggtcggc gtcgggaagg tcggcggtca
    16921 gctcggtcag cgtccgcagc agtgcggttc cgggaccgtc ggtcttcggg gctgctgaaa
    16981 ccggttcggc tggcgcgatg gtcacgtggg gctctccctc gctcggcggg ggcctcgcgg
    17041 agggcagcgg gcagcacacg agcgcggggc gcgccgcgtc caccggccca ttccgcgagg
    17101 cccggacgtc cagcacccga gccggacgga tcgggtgcgc tgccggcagg tgctcggact
    17161 gaccatgcgt gcgcgaaagc agaggaacgc acgcaagtac accgttgcgg gacagttccg
    17221 gattcgcacc ggattcccct gcggcgacag cgagcatgag catacatctt gtgccgggct
    17281 gccgcgcgac ccccagatgt tgtgtcggac cggcttcaca gtgtcaactc gtggagcgat
    17341 gggcccagtc ctgcgagcgg gagcgcgtac gacagcgggc cgccggggcg aggtgcctcg
    17401 gcggcccgct gtggccttgg gtggggagac gttccccctc gcgctagtgc cccgcccctg
    17461 ccgtcgccgg gggcagctcc acctggacgc ccgggtcgcc ggcgtccgcc gtgtagtccg
    17521 acggggacgt ctcgtcgacg ccctccgggg ccttcagcgc cctcatgacg aaggtcagca
    17581 ccaccgtcac cacgacgttc agcacgaacg ccgtgaggcc gatgtaaccg atctcgccga
    17641 tgccggggat ctccttcgac gagccgccga agtgcttctg ggtcggggag gcgacgccgt
    17701 acgccgccac cgtgccgtag accatgccga ccgcccagcc ggccagcagc gcccagcggt
    17761 ggaaccagcg ggtgaacagg ccgccgacca gggccgggaa ggtctggagg atccagatgc
    17821 cgcccagcag ctggaagttg atggcgaccg tcttgtccat ggtcaggacg aaggccagcg
    17881 cgcccacctt caccaggagc gagaccagct tggagacgcg ggtctcctcc ctgggcgtgg
    17941 cgtccggctt gatgaagtcc ttgtagatgt tgcgggtgaa gaggttcgcc gccgcgatgg
    18001 acatgatcgc cgccggcacc agcgcgccga tgccgatcgc cgcgaacgcc acgcccgcga
    18061 accagtccgg gaacatgtcc tcgaacaact gcgggatcgc cagctgcccg ttggagacct
    18121 tcaccccggc cgcgatcgcc atgaagccca gcagggcgag cagaccgagc atgagggagt
    18181 acagcggcag gatcgtggtg ttgcggcgga tcacgtcacg gctgcgtgag gacagcgtcg
    18241 cggtgatcga gtgcgggtac atgaacagag ccagcgcgga tcccaacgcc agcgtggcgt
    18301 aggtccactg gcccgcctcg ctcggcacca gcgaaccgcg tggcgcgccc gtcgccgggt
    18361 tggtctgcga gaaggcgtcg cccgccttgg cgaagatgtc gtcgaacccg cccagcttga
    18421 tggggatgta gatgatcgcc accgcgatga cgatgtagat cagcgtgtcc ttcacgaacg
    18481 cgatcagcgc gggcgcccgc aggcccgagg agtaggtgta ggccgccagc acgccgaagg
    18541 cgatcagcag cggcaggtcc ttgacgaacc agttggtgtc ctcaccgccg ccgacgccca
    18601 tcacgtccag cacggcctgg atgccgacca gttggagcgc gatgtacggc atggtggcca
    18661 ggatgccggt gacggccacg gccagggaca ggcccttgga gccgaaccgg ccgcgcacga
    18721 agtccgaggt cgtcacgtag ccgtgcttgt gcgacaccga ccacaggcgc ggcaggaacg
    18781 tgaagatcag cgggtagacg aggatcgtgt acggcaccgc gaagaagccc gccgcgccgg
    18841 ccgcgtagat cgccgccggg accgccacga acgtataggc cgtgtacagg tcgccgccga
    18901 gcaggaacca ggtgacccag gtgccgaacg accggccgcc caggccccat tcgtcgaggc
    18961 tgtgctcgtc gtcggccctg cgccagcgcg cggccaggaa gcccatgacg gtgacggcca
    19021 ggaagaagaa gatgaagacg gcgagggcca cgccgttcac gccgccgttc acttcgccgc
    19081 acccccgccc tggttcctac ggccgcgctg gtcgacctgc cacagcttgt acgcgaccac
    19141 cgtgagcatg gtggagagca gcacccacag catctggtac cagtagaaga acgggatgcc
    19201 gatgaacgcg gggtcggtct tcgcgtacga accgacccac agcatcgcca cgaagggcgc
    19261 gaacaggcag agggcgatga cgacgcgcaa aggcgtcacc accggccctc cgttgacttc
    19321 tggggcttgt gacatcgggc ggctccgtcc cctcgcagat catgtgcaac gcgcacgaaa
    19381 tgtaggtgac ggataaagcc aagcggaaga cctcgtccgc atatcggtcc cgtaggtcga
    19441 cggggtcgcc ggttactcca cgggttactc cacgggccgc ttcagccgcg cgacgaactt
    19501 gtaccggtcc ccgcggtaca ccgaccgcac ccactccacc gggaggccct ccctgtccac
    19561 ggagtggcgg gacagcatca gcataggcag accgacgtcc gtgccgagga ggccggcctc
    19621 gcgcggggtg gccagggagg tctcgatggt ctcctcggcc tcggcgaggt ggacgccgta
    19681 gacctcggcg agcgcggtgt agagggacgt gtacttcacc agtgacctgc gcagggccgg
    19741 gaagcgcttg gccgagaggt gggtggtctc gatggccatc ggctcgccgt tggccatgcg
    19801 cagccgctcg atgcgcagca cacggccgcc cgcggtgatg tccagcagac cggcgagccg
    19861 gtcgtcggcc gtgatgtagc cgatgtcgag gagctgcgag gtgggttcga ggccctgcgc
    19921 gcgcatgtcc tcggtgtacg aggtgagttg cagcgcctgg gagaccttcg gcttggccac
    19981 gaaggtgccc ttgccctgga tgcgctccag ccggccctcg acgaccagct cctggagcgc
    20041 ctggcgcacg gtggtgcgcg aggtgtcgaa ctcggccgcc agagtgcgct cgggcggcac
    20101 cggggtgccg ggcgactgcg tctccgtcat gtcgaggaga tgcttcttca ggcggtagta
    20161 cttgggcacg cgcgcggtac ggacggtcgc cccaccctcg ttctccgcac tgctgacgtc
    20221 ggtgctcatg tcctgccttc ccggctccgg ggtgccgaag cggccgacag tcccgtcggc
    20281 cgcggctcac atcgtggcac gggttcgtcg gcggggtatc cagtgcggtg acctcgcccg
    20341 gtccgtgatc tcttctgtat acctccggga cctccgttgg tctagtccaa catgtcggcc
    20401 agggccgatt ggttcagttc cccgcgaggg gccgatacgt ggcccgcgaa ttgaaaagtc
    20461 cctgcatatc gcggtcccgt aacggacgac tcaaccctgg ttgaacaccc ttgacagccc
    20521 aattggtctg agccaagctc cggcttactg gtctacacca ttggtccagg tcctggcccc
    20581 acggacggta cgcgttgacg ctcgaccgcg gcggggaggc aggggggttt gtgggatccc
    20641 tgaggagggt tggcgtgaag cgcaagctga tagccgcgat cggtatcgcg ggcatgatgg
    20701 tctccatcgc ggcgtgcggg gacgacaagg acagcggtgg ttcggacaag ggcaccgaag
    20761 ccaaggaact gacggtctgg ctgaccgtcg acgcgcagaa caactggccc gaactggtca
    20821 aggccgcgga cgcggcggtg cagaagaagc accccggcgt gaagatcacc cacgagtact
    20881 acggctggcc cgacaagaac gccaagctcg acgcggttct cgccaccgac aaggtgcccg
    20941 acgtggtcga gatgggcaac accgagatgc tcagctacat ggtcaagggc gccttcgccc
    21001 cgctcgacgc cgcgaagttc gacaactcct ccgcctggct ggacggcctc aag
//
