LOCUS       NZ_CP085431            23533 bp    DNA     circular CON 25-JUN-2024
DEFINITION  Priestia megaterium strain F20 chromosome, complete genome.
ACCESSION   NZ_CP085431
VERSION     NZ_CP085431.1
KEYWORDS    RefSeq.
SOURCE      Priestia megaterium (Bacillus megaterium)
  ORGANISM  Priestia megaterium
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Priestia.
REFERENCE   1  (bases 1 to 5241365)
  AUTHORS   Sun,X.
  TITLE     Bacterial competition corelates with biosynthetic potential among
            closely related bacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5241365)
  AUTHORS   Sun,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2021) College of Resources and Environment,
            Huazhong Agricultural University, Shizishan Street 1, Wuhan 430070,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 17-APR-2019
            Assembly Method                   :: CANU v. 1.7.11
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 328x
            Sequencing Technology             :: Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023824175.1-RS_2024_06_25
            Annotation Date                   :: 06/25/2024 06:00:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,444
            CDSs (total)                      :: 6,214
            Genes (coding)                    :: 6,101
            CDSs (with protein)               :: 6,101
            Genes (RNA)                       :: 230
            rRNAs                             :: 17, 16, 16 (5S, 16S, 23S)
            complete rRNAs                    :: 17, 16, 16 (5S, 16S, 23S)
            tRNAs                             :: 173
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 62 of 114
            Pseudo Genes (internal stop)      :: 19 of 114
            Pseudo Genes (multiple problems)  :: 15 of 114
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:50:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2793404
            Orig. end                         :: 2816937
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP085431.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23533
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="5"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23533
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23533
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13533](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13533)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            606..1286
                     /locus_tag="LIT34_RS14145"
                     /old_locus_tag="LIT34_14170"
     CDS             606..1286
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013083503.1"
                     /locus_tag="LIT34_RS14145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14170"
                     /product="DUF421 domain-containing protein"
                     /protein_id="WP_207371545.1"
                     /transl_table=11
                     /translation="MGYAESTFRIACSFFVLLLLTRLMGKTEISQLNVFTFITAITISN
                     IASSLSTDERVEIDKGVYSLLGWTFLTIAMGYIGMKSKKARHLITGEPKIVIKQGKVME
                     KALKQVRLDIESLLGMLRQQNVFSIKDVEYAILEINGNLSVMQKQDKKPNSWSKTLLFP
                     TSIGVIYDGKANEDALKDLHLDNNWLHKQIEKAGVKSIDEVFYAEVQSDGSLYIDYKKD
                     KFNS"
     gene            complement(1319..2806)
                     /locus_tag="LIT34_RS14150"
                     /old_locus_tag="LIT34_14175"
     CDS             complement(1319..2806)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013057419.1"
                     /locus_tag="LIT34_RS14150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14175"
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /protein_id="WP_041816573.1"
                     /transl_table=11
                     /translation="MNTQTQQSDQARTRSIFGVMIMGALVAFLNQTLINIALPQMMDHF
                     HVTAATGNWLTTIFMLVNGIVIPITAFLMNRFTTRQLYITAMGLFTVGTLLCGIAPTFS
                     VILVGRVVQAAGAGILFPLITNVIFTLFPPDRRGFAMGIFGVAMNFAPAVGPTLSGLIV
                     EHYSWRVLFFMMFPIALINVIAAIILVKNVTETSRPKLDVLGVILSTIGFGGLLYAFAT
                     GGTKGWTSTEVLAMFIVGGISILFFIFRQLKIDQPLLEFRIFRYRMFTLTTIINVIVTM
                     AMFSGMILMPIYMQNVRGFSPFLSGLLLLPGGIVMGIMSPITGRLFDKFGARWLAVIGL
                     AITVVTTYELTKLETTTTFMYVMIVYTVRMFGMSLLMMPIFTAGLNELALSLNKYGTAM
                     VNTLRMVAGAVGMAFFVSIMMNQGEKHVKNIVMNQQILPTDKGSMTEAVNQGTAMGIND
                     AFMIATILSVIAFVLAFFIRKTSPKEDTITNRVKKAS"
     gene            complement(3086..3643)
                     /locus_tag="LIT34_RS14155"
                     /old_locus_tag="LIT34_14180"
     CDS             complement(3086..3643)
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014459735.1"
                     /locus_tag="LIT34_RS14155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14180"
                     /product="3D domain-containing protein"
                     /protein_id="WP_013057420.1"
                     /transl_table=11
                     /translation="MKKTMITFSLVLMSLFGVASGASAATNTYTVKSGDSLYKIAKTYK
                     VSVSQLKQWNNLKSDSIHPKQVLKVSQAKSSTPAKAAPAKSSNVVKEFKVTATAYTANC
                     KGCSGKTAIGIDLKKNPNQKVISVDPKVIKLGSKVYVEGYGTAIAADTGGAIKGNKIDV
                     LLPSQKEALKWGRKTVKVQILK"
     misc_feature    complement(3924..3937)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.08"
                     /tool="antismash"
     gene            complement(3968..4102)
                     /locus_tag="LIT34_RS32155"
     CDS             complement(3968..4102)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014461094.1"
                     /locus_tag="LIT34_RS32155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_013057421.1"
                     /transl_table=11
                     /translation="MIGEQDEDSCGNSGTDETPQERKRRGGSSPARGKRSLARKSAAV"
     gene            complement(4261..5145)
                     /locus_tag="LIT34_RS14160"
                     /old_locus_tag="LIT34_14185"
     CDS             complement(4261..5145)
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014459734.1"
                     /locus_tag="LIT34_RS14160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14185"
                     /product="superoxide dismutase"
                     /protein_id="WP_013057422.1"
                     /transl_table=11
                     /translation="MADQDERKRYLMEVQTWLEQVCDPVFEEAITEVDITSYITRTQED
                     VLEYLSEEDVNEYTLEEINNAVRHIDKVLKERLGDDGRERESIAPGRHELPPLGYSYSA
                     LEPYINREIMRLHHSKHHQSYVDGLNKAELMLQQARNTNNFDLIKHWEREAAFHGSGHY
                     LHTIFWEIMSPEGGGRPRRQLLQQLQKDFGSYEKFMMHFSQAAKKVEGVGWAILVWSPR
                     SRKLEVLQAERHQLLTQWDTIPLLVLDVWEHAYYLQYKNERDPYVDNWWKIVYWPNVEK
                     RFEAARMLQWQPY"
     gene            complement(5286..6116)
                     /locus_tag="LIT34_RS14165"
                     /old_locus_tag="LIT34_14190"
     CDS             complement(5286..6116)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013083507.1"
                     /locus_tag="LIT34_RS14165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14190"
                     /product="hypothetical protein"
                     /protein_id="WP_053487356.1"
                     /transl_table=11
                     /translation="MLDQYEKINSTYDKIDELQLPFDKPVLVAIEWNGVLFEFLVRLKK
                     ESSHLLVFGSGGGASQEMPAGPPYFQRHSWMNEFEDSIIYYNDPTLYLGKVSLAWGQGT
                     SNRFYLKDIAVLIEKFMKKAQVNSSNVLFYGSSGGGFMSMFLAGYVKGAKALVNNPQTC
                     LTKWLKTPVRQVFNLSYPNLTEEEVIVSYGERINVVKFFSHINYVPKIYYLQNGAFEYD
                     MDNHLLPFLTDLQHMPDGCEINNIKVDLYYNPKLKHAAVSKQETIDYVNMAKNI"
     misc_feature    complement(6097..6111)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.92"
                     /tool="antismash"
     gene            6346..7011
                     /locus_tag="LIT34_RS14170"
                     /old_locus_tag="LIT34_14195"
     CDS             6346..7011
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013083508.1"
                     /locus_tag="LIT34_RS14170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14195"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_055992859.1"
                     /transl_table=11
                     /translation="MSTSYMDYNNPNVQYFSDVNKNRLNTRNDQNYINRLGRDVLNTLG
                     NVSLLDIYLSKRRVVEPHYHQNASELVYCISGSAVVSLINPFNNEVTNIPIAPGQVANI
                     PQGWWHWEIASEDNTHLLAIFDAPYPEYIFGSDILNKTPIEVLAHTYCLDPEQLKKTLA
                     PLKNQTIVIGPTDECVEKGPYKQKKQAGSASHETPPYKYPPPQNPYYSPQNPYHYRYW"
     gene            complement(7066..7299)
                     /locus_tag="LIT34_RS14175"
                     /old_locus_tag="LIT34_14200"
     CDS             complement(7066..7299)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016764475.1"
                     /locus_tag="LIT34_RS14175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14200"
                     /product="hypothetical protein"
                     /protein_id="WP_013057425.1"
                     /transl_table=11
                     /translation="MYYYRISEGQDEMYSETIVVHEEQFDQGTFEEMVKEAMVDKPGKI
                     DQVDIVKYLIGHYHFQVAYIEAAFHSTYIEEQ"
     gene            complement(7364..7948)
                     /locus_tag="LIT34_RS14180"
                     /old_locus_tag="LIT34_14205"
     CDS             complement(7364..7948)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016764476.1"
                     /locus_tag="LIT34_RS14180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14205"
                     /product="hypothetical protein"
                     /protein_id="WP_013057426.1"
                     /transl_table=11
                     /translation="MSYKQYWGNIHEQSDKLQELLSSYWHQYSDFGNWQFWVVLASLVL
                     PLVLLYFTVDRTRIFEVFFFGYTVHMLWAYIDIALGRSGYLTHTFFLTPLLPNATNITA
                     SILPVGFLLLYQYCTNHQKNFYLYTILLSAVFSFGLAPLEHHFKFIDSRKGMSLFYIFL
                     IDIGITLVAYWVTRLLVKAKAAAYRTAEKER"
     gene            complement(8180..>8349)
                     /locus_tag="LIT34_RS14185"
                     /old_locus_tag="LIT34_14210"
                     /pseudo=""
     CDS             complement(8180..>8349)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013083843.1"
                     /locus_tag="LIT34_RS14185"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="LIT34_14210"
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="IIAGFIGAWLGGLIFGDWGPDISGFAVILLLSDLLFS"
     misc_feature    complement(8391..8404)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.9"
                     /tool="antismash"
     gene            8452..8991
                     /locus_tag="LIT34_RS14190"
                     /old_locus_tag="LIT34_14215"
     CDS             8452..8991
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013056634.1"
                     /locus_tag="LIT34_RS14190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14215"
                     /product="YhcN/YlaJ family sporulation lipoprotein"
                     /protein_id="WP_252282046.1"
                     /transl_table=11
                     /translation="MKKRKYLLGLLSTILSVGVLFGCNDKKDEAEPDPTEEPSEQRAEN
                     ARNNNGPRNVGFEPNEENNDKNQTKLEVADEAANRIAKLDEVDSANVIVTNRNAYVAVV
                     LQDGTNGKVTDRLEKKIADQVRATDSDIQEVYVSANPDFVNRMKDYEKRINEGAPVKGL
                     FEEFTVTVQRVFPNAR"
     misc_feature    complement(9105..9118)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.88"
                     /tool="antismash"
     gene            9223..9738
                     /locus_tag="LIT34_RS14195"
                     /old_locus_tag="LIT34_14220"
     CDS             9223..9738
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107035.1"
                     /locus_tag="LIT34_RS14195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14220"
                     /product="undecaprenyl-diphosphatase"
                     /protein_id="WP_013057428.1"
                     /transl_table=11
                     /translation="MDYKMFRTINQLAGRYSTIDMLMILISKKVRYVFMFVLIFMWFRN
                     YSQKKVTIYAVTSSAFTLFINTLIKCFYFKPRPFIKRRVGILIPSKMDSSFLSKHTLLT
                     FAVSTSIFLHERVIGSVMWGLALLTGFSKIWVGHHYPSDIIRSAFIGSVTSITIDKTAR
                     FFNSFIRL"
     gene            complement(10001..11569)
                     /locus_tag="LIT34_RS14200"
                     /old_locus_tag="LIT34_14225"
     CDS             complement(10001..11569)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003252868.1"
                     /locus_tag="LIT34_RS14200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14225"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_013057429.1"
                     /sec_met_domain="PF00881 (E-value: 2e-06, bitscore: 26.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLETFLYNLHFDIDKASPTDWEVDWEDAPLPYKLYRDLPVFPLS
                     LEVPLSLEQWAAPEQPNLQRMSHFLWYVFGLTQISQSAFSTTDQEPELMQSYRRFVPSG
                     GALYPNELYVYLKTEDLPVGMYHYDVAHHRLVLLREGNFDSYIAQALGNRCDVSACFGT
                     FFVSTMFWKNFYKYNNFAYRLQGLDAGVLIGQLLEVAKRFGFASGVYFQYLDRAINHLL
                     GLNEEEESVYAVIPLTVEPTSWFTNRGGKEPVSAIELCRELPVIQNNHYVRSQRIKAFP
                     MLKKMNEASMLESKQSFRQIKVREKVNCKSQVVTLPHMKRLSYDLASVCQKRFSPDMDF
                     IFGKVSQLQLATLLQEATSAYLYRNDLDEAHKKNEPRVSLYVCLNNIEGIPDGAYHYDS
                     ANHALRQVDLGDHRLSLQYGMPVGNVNLSQVPFCFHVAGDKDHFISELGYRGYRIQQME
                     AGMLVQRLLLAASAIDMGGHPLLGFDANLCDEIYKMEQQGKTSLIQIPTGPYRPRPWLK
                     GSLQS"
     gene            complement(11593..13533)
                     /locus_tag="LIT34_RS14205"
                     /old_locus_tag="LIT34_14230"
     CDS             complement(11593..13533)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013877478.1"
                     /locus_tag="LIT34_RS14205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14230"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_013057430.1"
                     /sec_met_domain="YcaO (E-value: 4.1e-79, bitscore: 264.9,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.3e-127, bitscore:
                     424.0, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVVVIIGEGMLADHVYEQLSDQYQVVRHIDFEAELPEAADLVL
                     VLDDAWNPSLHQKAEEVLRPTGIRWLRGFVSFGEGVIGPLVGSDTPGCSRCADIRHLMA
                     GRDRKEMWEMQQQLAADGGVTRDAWASSLGLLQIACLLGREVQRIVQGDEVHSEGQVCL
                     INLKTLKSSWHTFLSDPLCPGCSQLPDDSPAAARISLKSSPKITDSYRCRSMDDLNKVL
                     VKDYLDQRMGILNGKMYDLVPPFADVVVNLPLFSGDEGVAGRTHSYAVSELTAILEGLE
                     RSCGMTPRGKRTVEYDSYRNLKDQAINPIEVGVHAKERYAEPGFPFEQFHPDRPIKWVW
                     GYSFLQERPILVPELLAYYSLGCGQGFVYETSNGCALGGSLEEAIFYGILEVVERDSFL
                     MTWYAELPLPRLDPYSANDQELELMIDRVRAIGGYDLHFYNSTMEHGIPSVWAMAKNRK
                     KKGLNIICAAGAHLDPVRAVKSTIHELAAMMLTLDEKLETNQEEFVRMLQDSSLVQKMD
                     DHGMLYGLPQAQERLQFLLDDNRPLRSFAEEFKWKSNSADLTDDLQDILQKFRRLNLDV
                     IVVDQSTPETKRNGLYCVKVLIPGMLPMTFGHHLTRVTGLERVLRVPMELGYKKKPLTF
                     EQLNPHPHPFP"
     gene            complement(13530..15482)
                     /locus_tag="LIT34_RS14210"
                     /old_locus_tag="LIT34_14235"
     CDS             complement(13530..15482)
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003340798.1"
                     /locus_tag="LIT34_RS14210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14235"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_013057431.1"
                     /sec_met_domain="TIGR03693 (E-value: 1.5e-237, bitscore:
                     788.1, seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     1.3e-52, bitscore: 174.1, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 4.3e-13,
                     bitscore: 47.3, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNLNPSMRLKVKRDTFFLPDPNSGVYFRNNISSFHMKGSMIDQW
                     VKKLIPMFNGEYTLESLTNGLPGPYRERVYEIAEVLYQNGFARDASQDRPHQLADPVLK
                     KYASQIEFLESFGDSAAYRFQAYRQARVLAIGSGSFFVSLVSSLIESGLSKFHVMITDS
                     VPTNQLRLEGLVGHARKTDPEVAIEEVILEKDGGNSWREIVQPFDSILYVSQEGDVEEL
                     RALHKICREEKKVLLPAIFLHQVGLAGPLVHPGSEGCWESAWRSIHESVFRNDEQLPSF
                     TSTAGAMLANVIVFELFKNVTRVAESEQKNQFFLLNLDTLEGNWHSFMPHPLVTGRVTA
                     EWVQDFDLRLKQSSSRGESSGLLLYFSQLTSKESGIFHILEEEDLKQLPLAQCHVQVVD
                     PLSKGPAELLPSMVCTELTHEKARKEAGLSGVEAYVSRMVDAFLTTLPSQQKAERVIVE
                     SEEFVGVGAGETIAEGVCRGLQKCLTEELSKQLIDQKNIVSRVQVSDVEDEHCRYCLQA
                     LTVTQGAPIIGLGKEVSGFPVVWVGTNDRWYGSVGLNTTMALQKALQQALMNKENQATQ
                     VLPNSSVFLVEKVPKSLVIQKSEEISHSEVLRSAMQVLEQNGKRLLFFELALEPFCKKE
                     LVGVYGMLLREEESK"
     aSDomain        complement(15186..15482)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_LIT34_RS14210_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="6.70E-55"
                     /identifier="RREFam011.1"
                     /label="LIT34_RS14210"
                     /locus_tag="LIT34_RS14210"
                     /protein_end="99"
                     /protein_start="0"
                     /score="174.1"
                     /tool="antismash"
                     /translation="MTNLNPSMRLKVKRDTFFLPDPNSGVYFRNNISSFHMKGSMIDQW
                     VKKLIPMFNGEYTLESLTNGLPGPYRERVYEIAEVLYQNGFARDASQDRPHQLA"
     aSDomain        complement(15222..15461)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_LIT34_RS14210_Thiopeptide_F_RRE.1"
                     /evalue="2.30E-15"
                     /identifier="RREFam004.1"
                     /label="LIT34_RS14210"
                     /locus_tag="LIT34_RS14210"
                     /protein_end="87"
                     /protein_start="7"
                     /score="47.3"
                     /tool="antismash"
                     /translation="MRLKVKRDTFFLPDPNSGVYFRNNISSFHMKGSMIDQWVKKLIPM
                     FNGEYTLESLTNGLPGPYRERVYEIAEVLYQNGFA"
     gene            complement(15663..15911)
                     /locus_tag="LIT34_RS14215"
                     /old_locus_tag="LIT34_14240"
     CDS             complement(15663..15911)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03601.1"
                     /locus_tag="LIT34_RS14215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14240"
                     /product="hypothetical protein"
                     /protein_id="WP_155660458.1"
                     /transl_table=11
                     /translation="MLDLGDFQANQAIPWDPNNMDQDRQFGIFFRCFSCFSCFTCFNCF
                     NCFNCFRCSNCFRCGGNCGGRCGGNCGGRCGGGRCGG"
     gene            complement(16570..19665)
                     /gene="ileS"
                     /locus_tag="LIT34_RS14220"
                     /old_locus_tag="LIT34_14245"
     CDS             complement(16570..19665)
                     /EC_number="6.1.1.5"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ileS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013057433.1"
                     /locus_tag="LIT34_RS14220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14245"
                     /product="isoleucine--tRNA ligase"
                     /protein_id="WP_053487357.1"
                     /transl_table=11
                     /translation="MKEVNVRESSQEREQRIQQQWQKGNVFQQSVQNREGHPSFVFYEG
                     PPTANGLPHVGHALGRTIKDVVARYKTMTGHQVIRKAGWDTHGLPVELGVEKQLGISGK
                     HDIEKYGVEAFINKCKESVFVYEKQWRTFTEQLGYWVDMEDPYITLENSYIESVWNVLG
                     TIHDKGLLYKGHRVSPYCPSCQTSLSSHEVAQGYKDVKDLTVTVKFKVKNRDNEYFLGW
                     TTTPWTLPSNVALAVHEEMNYVRAEQGDSVYIVAEALADKVLKGEYTVLSQHKGNELKG
                     MSYEPPFNFVKVEKGHEVVTADYVTDQSGTGVVHLAPAYGEDDYRVVKENGFSFVNVVD
                     EKGQYTAEVPPFQGRFVKDCDVDIVRYLANQDVLYHKEKHEHSYPFCWRCDSPLLYYAN
                     ESWFIQTTALKEQFLKNNESVTWYPDHIKHGRFGNFLENMVDWNISRKRYWGTPLNVWE
                     CGKCQHQVAPKSIKELQKHASHFVDDSIELHKPYVDDMQLTCPVCSGEMKRTAEVIDVW
                     FDSGSMPFAQYHYPFENSELFQKQFPADVIAEGIDQTRGWFYSLMAVSTLFTGKAPYKR
                     VLSLGHVLDENGQKMSKSKGNALDPVDLIHTFGADALRWALLADSAPWNPKKFSERVVQ
                     EAKSKVIDTLVNVYGFYVLYAKLDGYDPEQTYELKKTKLDEWILSRLHSTVKRVTAHLE
                     DYGFTSAAREIAVFIEELSNWYVRRSRDRFWSEGMDGEKAAAYDTLHEVLVTLSQLLAP
                     FTPFVADDIHENLTGKSVHLVDYPVYNEGKVNEKLEREMAAVLQVVELGRSIRNTHSLK
                     VKQPLRSLSLVVTNEDIEWNAYRDVIKDELNVKKFNVEQDDENLVSYVLKLNFKQAGPK
                     FGKQVNAVNQTLKNLSADETKDFVQQGERRVTLPSGEKLTLETADVLVEKVPKEGFAVA
                     SNGMYTAVLDTALTEALVQEGLAREVIRAVQDYRKKLDLPVNLRIDLELSGDAEVKEAV
                     TSFEGLLQENLLLNSLCFTEDTEDGEKLKVGTKHVTLRMLNQ"
     misc_binding    complement(19718..19960)
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     gene            complement(20050..21036)
                     /locus_tag="LIT34_RS14225"
                     /old_locus_tag="LIT34_14250"
     CDS             complement(20050..21036)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013083515.1"
                     /locus_tag="LIT34_RS14225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14250"
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="WP_252281537.1"
                     /transl_table=11
                     /translation="MLRKSGAKRIQAWFYDDDPNGIKVSEVPNTTIQAVFIPRNSLKDL
                     KGESEVEKPGIYFLFGEDKEAYIGEAEVGYERLRQHASPSTGKSFWDVAVLIVSNASQD
                     QLDKVDVKYLEHISYLAAMRSGTYDINQTVPTKPFVREFRRDDLTDIFNVIKVLLGGLG
                     FSIFADASNGIEYESGAVQSGDIPKIEAEQAIEKVVQVETHLSKDIKSVIVEDVLYCKR
                     RDAYATGKYVSDGFLVYKGALLASEQQLEGAKLKRQQDHINTFLANGVLEIKDGRYVLV
                     QDQIFSSISAAAVFVTQRRSSGTSEWKDKNGITACNKIDQMLSAETK"
     gene            complement(21139..22020)
                     /locus_tag="LIT34_RS14230"
                     /old_locus_tag="LIT34_14255"
                     /pseudo=""
     CDS             complement(21139..22020)
                     /GO_function="GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_063671828.1"
                     /locus_tag="LIT34_RS14230"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="LIT34_14255"
                     /product="phosphorothioated DNA-binding restriction
                     endonuclease"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNREEVLQKIKNLNIWKKRDQRAPHKPLLILYALGQLQAKQQMHL
                     PYREVKIPLKELLMEFGPSRSSYHPEHPFVRLTGDGIWELSEEVDKRSFTDKYLLSKNI
                     IGGFR"
     misc_feature    21991..22000
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    complement(23027..23036)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    23261..23276
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.16"
                     /tool="antismash"
ORIGIN
        1 gtatttatgc gtacccgtat acttctgtgc gtacacatat gtttttcggt cacgcgcttc
       61 cacgtagata atttttgaga aaggaaccgg tatccatccc tcgttcacct ttaacgtcac
      121 aactgacttt ccgctcgtta acgcaggaaa aatcgccgtc acgcatcctt gaacttctcc
      181 ttcatctaaa aaaggcacgg ccatgccgta gtaaggcgtg ccaaacacgt ctcggtgaat
      241 aaattccgat actttttgct ttcgttctaa tgctttatat gtaatcgttc cttttttgat
      301 ttgatctcca gggctaattt ttaaattaat tcgtttgctt gcccggtaat acacgtacgt
      361 ttctagatct gaaacagcaa tcgacgcttc atcagagaac aattcgctga taacgtctaa
      421 taatgctgaa gctttaaatg gtttcatctt ttcaccttct tttgtctagt caaacacgct
      481 gcttctttat tgtagcgcaa aagcaaaagc gagtgggaaa gaagcatgga atttatcttt
      541 tcaactgtat aaaatttcta ttttttcaca acataaaaca atgaaatgaa ggaagggtga
      601 aatgtatggg ctatgctgaa tcgacgtttc gaatcgcctg ttcatttttt gtgctgcttc
      661 ttttaacgcg gctcatggga aaaacagaaa tcagccagtt aaatgtattt acatttatta
      721 cggcaattac gattagtaat atcgcttctt ccctctccac tgatgagcga gtagagattg
      781 ataaaggggt ttattcactg ctaggttgga catttttaac gatcgctatg ggctatattg
      841 gaatgaaatc gaaaaaagca cggcatctta ttaccggcga acccaaaatt gtgattaagc
      901 aaggaaaagt gatggaaaag gcattaaaac aagtacggct agatattgaa tctcttttag
      961 gcatgctgag gcagcaaaac gtattttcca taaaagatgt agaatacgcc atattagaaa
     1021 tcaacggaaa cctttccgtt atgcaaaaac aagataaaaa gccgaactcg tggtcaaaaa
     1081 cgcttttatt tcccacttca ataggcgtta tttacgatgg aaaagcgaat gaagatgcgt
     1141 tgaaggacct gcatttagat aacaattggc ttcataagca gattgaaaaa gctggagtca
     1201 aatcaattga tgaagtgttt tatgctgaag ttcagtcaga cggatccctt tatattgact
     1261 ataaaaaaga caagtttaac tcataaaaaa atccgtacca aaaggcacgg attttttatt
     1321 agcttgcttt tttcacacga tttgtaatgg tatcttcttt tggtgatgtt ttgcgaataa
     1381 agaaggctaa aacaaacgcg atcacactta aaatcgttgc gatcataaac gcatcgttaa
     1441 tgcccattgc cgtaccttga ttcacggctt cagtcatact gcctttatct gtcggcaaaa
     1501 tttgctgatt catcacgatg tttttcacgt gtttttcacc ttgattcatc ataatggaga
     1561 caaagaacgc cattcctaca gctccagcaa ccattcgaag cgtattaacc atcgctgtgc
     1621 cgtatttatt taagctaagc gcaagttcat ttaaccctgc tgtaaagatt ggcatcatga
     1681 gcagcgacat accaaacata cgaacagtat aaacaatcat tacatacata aatgttgttg
     1741 tcgtttcaag ttttgttaat tcatatgttg tcacaacagt aatcgctaaa ccaataacag
     1801 caagccatct tgcgccgaac ttatcaaaca gccgtcctgt aatcggagac ataatcccca
     1861 ttacaattcc ccctggcagt aacagcaagc ctgaaagaaa cggtgaaaaa ccacgtacgt
     1921 tttgcatata aatcggcatt aaaatcatac ctgaaaacat tgccattgtc acaatcacgt
     1981 taatgattgt tgttaaagtg aacatacggt aacggaaaat acggaattca agaagcggct
     2041 gatcgatttt taactgacgg aaaataaaga acagaattga aataccgcct acaatgaaca
     2101 tggctagtac ttcagtgctg gtccagccct ttgtaccgcc cgtagcgaac gcatacagca
     2161 agccgccaaa tccaattgtt gataaaataa cgccaagcac gtctagctta ggtcggcttg
     2221 tttctgtcac gtttttcact aaaataatcg ccgcaattac gttaataagt gcaattggaa
     2281 acatcataaa gaataaaacg cgccatgagt agtgctcaac tattaaacca gaaagcgtcg
     2341 gacctactgc tggtgcgaag ttcatcgcta caccaaaaat tcccatcgca aaaccgcgtc
     2401 ggtcaggcgg gaataacgta aagataacgt tggtaattaa cggaaataaa atcccagctc
     2461 ctgctgcttg cacgacgcgt cccactaaaa taacggaaaa tgtcggtgca ataccgcaaa
     2521 gcagtgttcc tactgtaaac agacccattg ctgtaatata cagctgcctt gtagtaaatc
     2581 gattcattaa aaatgctgta attggaataa caattccgtt tactaacata aagatggttg
     2641 ttaaccagtt gcccgtagcc gccgttacat ggaaatgatc catcatttgc ggaagcgcaa
     2701 tgttaatcag cgtttgattt aaaaaagcga cgagcgctcc cattatcatt acgccaaaaa
     2761 tagaccgagt tcgggcttga tcggactgtt gtgtttgtgt attcatttta acaagacctt
     2821 tccctttaaa attatctgta tgtaaatctt cagatgacaa acaggttaag aatatatttt
     2881 atgtgttcat tctattaatt tatgtcacga atatttaatg aacttaatta tataccggat
     2941 aaatatatct gtttccgaaa tatttgtcaa caaatatgat cattttcgta aaacttttcc
     3001 atcagtatat ataaagtagc atgcccttta atgaagaaaa aaatgagagc ccttcaacga
     3061 aggctctcat ttccttaaga aatacttatt ttaagatttg aacttttact gtttttcttc
     3121 cccattttaa cgcttctttt tgagaaggaa gaagaacgtc aattttattt cctttaatcg
     3181 caccgcccgt atcagctgcg attgccgtgc cgtaaccttc tacgtatact tttgaaccaa
     3241 gtttaatcac ttttggatcg acagaaatca ctttttgatt tggattcttt ttcaagtcaa
     3301 ttccaatcgc tgtttttccg ctgcagcctt tgcagttcgc tgtgtacgct gttgctgtta
     3361 ctttaaattc tttcacaacg tttgaagact tcgcaggcgc tgctttagca ggcgtgcttg
     3421 attttgcttg agatactttt aatacttgtt ttggatgaat gctgtctgac tttaagttat
     3481 tccactgttt cagctgacta accgatactt tatatgtctt tgcaattttg tatagcgaat
     3541 ctccgctttt tactgtatat gtatttgttg cagctgatgc accacttgcc actccgaaca
     3601 gtgacattag aactaaactg aacgtaatca ttgtcttttt catgtaattg atttcccctt
     3661 tatctaccaa tacataaaaa ataacacatg aatattacag ttatatttca gtaacatgtc
     3721 aatagtttga tagtttagtt acagtaaaaa taaatattct tccttttaaa ctagtaaaat
     3781 aatcaccttc acactttaaa aacatacata tttaggcata taacgggggt tttacacaca
     3841 tttatacgta attgtttcat ttgtaacatt caactggttc tagaggctta tgctttattt
     3901 taaattgatt atttagaaca tagtttattt aaaaaaatga aataaaggat ctaatataaa
     3961 tcacttttta caccgctgct gatttccgtg caagacttcg ctttccgcgg gcgggcgatg
     4021 agcctcctcg tcgcttacgc tcctgcgggg tctcatctgt tccgctattc ccgcaggaat
     4081 cttcgtcttg ctctccaatc aatagctaga agccactaca tacatgattg tcataacaat
     4141 gaaaaaatcc gaacgagttt gattctcaat caagaatcaa actcgttcgg attttacttc
     4201 aattaaaata ctgtggtccc agcttctttt atctttaaat tataatggtt acactaattt
     4261 tcaatatggc tgccactgaa gcattctagc tgcctcaaac cttttttcta cattcggcca
     4321 gtaaactatt ttccaccagt tgtcaacgta cggatcacgt tcatttttgt actgcaaata
     4381 ataagcgtgt tcccatacgt ctaatacaag cagcggaatg gtgtcccact gcgtaagcag
     4441 ctgatgacgc tccgcttgca gaacttcgag cttgcgcgaa cgcggggacc atactaaaat
     4501 tgcccacccc acaccttcta cttttttagc agcttgagaa aagtgcatca taaatttctc
     4561 atagctgcca aagtcttttt gaagctgctg caacagctgt cgtctcggtc ttcctcctcc
     4621 ttctggactc ataatttccc aaaagattgt atgcagataa tgaccagatc catgaaaagc
     4681 agcttcccgt tcccagtgtt ttatgaggtc aaaattattt gtgttacggg cttgctgcag
     4741 catgagctct gctttattta atccatcgac atagctttgg tgatgcttgc tgtgatgaag
     4801 acgcataatt tcccggttaa tatacggctc aagagctgaa tagctatagc caagcggcgg
     4861 cagctcgtgt cgtcccggcg ctatagattc ccgctccctg ccgtcatctc caagtcgctc
     4921 ttttaaaact ttatcaatat gccgcaccgc attgttgatt tcttctaacg tatattcgtt
     4981 aacatcttct tcacttaaat attcaagaac gtcttcttgc gtgcgcgtga tatatgacgt
     5041 tatatctact tctgtaatgg cttcttcaaa tacagggtca cacacttgtt caagccaggt
     5101 ctgaacttcc atcaagtatc tttttctctc atcttgatcg gccatacttc ccctccttac
     5161 acctcatctt cactatcata ttcaaaagaa aaagcaacat aactgcctac ttgtatctat
     5221 tgagttagaa aattcgacat aaaaaaggca aaggttcctt tacacttgaa ctcttgcctt
     5281 ttttcttata tattctttgc catattcaca taatcaatcg tttcttgctt actaacagcc
     5341 gcgtgcttca gctttggatt gtaataaagg tccactttta tattattgat ttcacagccg
     5401 tctggcatat gctgcaaatc cgttaaaaat ggaagcaagt gattgtccat atcatattca
     5461 aacgccccgt tttgcaaata atatatcttt ggcacatagt taatatggct aaaaaacttc
     5521 actacgttga ttcgctcacc gtatgagact atcacttcct cttctgtcag gttgggataa
     5581 gataaattaa acacttgccg aaccggcgtt ttcagccact tggtcaaaca ggtctgcgga
     5641 ttattaacaa gcgcttttgc tccttttacg taccccgcca aaaacatcga cataaagccg
     5701 ccgcctgaag atccgtaaaa cagcacgtta gacgaattca cctgcgcttt tttcatgaat
     5761 ttttcaatta aaacggcaat gtcttttaaa taaaaacgat tgctcgtccc ttgtccccac
     5821 gcaagcgaca cttttcctaa ataaagcgta ggatcgttat aataaataat ggaatcttcg
     5881 aattcattca tccacgaatg ccgctgaaaa tatggaggtc ctgccggcat ttcctgactt
     5941 gctcctccgc ctgaaccaaa cacaagcaaa tgcgaagact ctttttttaa tctgactaaa
     6001 aactcaaaca gcactccgtt ccactcgatc gccactaaaa caggcttatc aaatggcagc
     6061 tgaagttcat ctatcttatc atacgtacta tttatttttt catattgatc aagcaacagc
     6121 tctgcaactc actttcctta aaatgatacg tcatatgtgt ctgacattga tcatggttct
     6181 gtgaaaaaag aacctgtcac agtatatgaa aaccaacggg caaatgattg tacacttcct
     6241 ccaaaagagg cggttaccta catcttcctg ggcttttgtc acgaaataaa actctctaca
     6301 tacgatacag catcataaaa atttaaaaat aggagctgaa gagccttgtc aacgtcctat
     6361 atggattata acaatccaaa tgtacagtac ttttctgatg tgaataaaaa cagacttaac
     6421 acgagaaacg atcaaaatta cattaaccga ttaggccggg atgtgctgaa tacactagga
     6481 aatgtgtcgt tacttgatat ttacttaagc aaaagacgcg tggtcgaacc gcactatcat
     6541 caaaatgcct cggagcttgt ctactgcatt tcaggatcag ccgtcgtttc attaatcaac
     6601 ccgtttaaca atgaagtgac aaatattcca attgccccgg ggcaagtagc caatatccct
     6661 caaggctggt ggcactggga aattgcgtct gaagacaata cgcatttact tgccattttt
     6721 gacgctccgt atccggaata catttttgga tcggatattt taaataagac gcctattgaa
     6781 gtacttgctc atacgtactg cttagatccg gagcagctaa agaaaacgct ggctccgtta
     6841 aagaatcaaa ctatcgtgat tggaccaacg gacgaatgcg tagaaaaagg gccttacaaa
     6901 cagaaaaaac aagcaggctc cgctagccac gagacgcctc cttataagta tcctccgcct
     6961 cagaatcctt attactcccc tcaaaatccc tatcactatc gatattggta aagacaagaa
     7021 aaccccgctg ccaatgcaac ggggtttctt aacgaataca taacattatt gttcttctat
     7081 atacgtgcta tgaaaggctg cttcaatata tgcaacttgg aaatgataat gtccaattaa
     7141 atatttcaca atgtccacct ggtcgatttt gccgggctta tcgaccatcg cttcttttac
     7201 catttcttcg aatgtacctt gatcaaactg ttcttcatgg acaacaattg tctcagagta
     7261 catttcgtct tgtccttctg aaatgcgata gtaatacaat tttttcacct cgatttgtct
     7321 tgagtgtatg tataccctta actgataatt ttaaaacatt ttttcagcgt tctttttccg
     7381 ctgtacgata tgctgcggct tttgctttta caagcagcct tgtaacccag tacgccacta
     7441 gcgttattcc tatatcaata aggaaaatat aaaacaaact cattcctttt cttgaatcaa
     7501 taaatttaaa atgatgttca agaggcgcca gtccaaacga aaaaacagcg ctcaacagga
     7561 ttgtatatag ataaaaattc ttttgatgat ttgtacaata ttgataaagc agcagaaatc
     7621 ctaccggcaa aatagatgcc gtaatgttcg ttgcgttcgg aagcagaggc gttaagaaaa
     7681 acgtatgcgt taaataaccg cttcgtccaa gtgcaatatc aatatatgcc caaagcatat
     7741 gcaccgtgta accaaagaaa aatacctcaa agatcctcgt ccggtctacg gtaaaataca
     7801 acaacacaag aggaagaacg agcgaagcaa gcaccaccca aaactgccag tttccaaaat
     7861 ctgaatactg atgccaatac gacgataata actcctgcag cttatcgctt tgttcatgta
     7921 tgtttcccca gtattgttta taactcactg aagtaccctc ctatatagaa tctctgctta
     7981 tgtatgctct aacaagtaag tttctataca aaaagattat agatacatca tttcttagta
     8041 caataaaaaa gggaattaat aatagctgct ttgtcctaac ataatagcta tacatgatac
     8101 ttgtttttgt caatcaacta atacttttct taggcatatg taaaacattt tccttctctt
     8161 tttagttttt tcttatccat tatgtatgtc tacgattgcc aaaacgtatt ttcctcgtaa
     8221 taaaacttac aatcactacg aaaataatag atcggacaat agcaggataa cggcaaatcc
     8281 actaatgtct ggtccccagt ctccaaagat aagcccacct aaccatgcac caataaaacc
     8341 agcaataata taacactatg cttattttga ttattaaatt attgcctgta ttttttttga
     8401 aaataattgg aatgctaaag ttatacgact actacaagga gtgaaaacaa gataaagaaa
     8461 agaaaatatt tattaggtct cctatcaacg attttatctg taggagtcct ttttggatgc
     8521 aatgataaaa aggatgaagc tgaacccgat ccaactgaag aaccttctga acaacgtgca
     8581 gagaatgccc gtaacaacaa tgggccacga aatgttggat ttgaacctaa tgaggagaat
     8641 aatgataaaa accaaacaaa attagaagta gctgatgagg ctgcaaatcg cattgccaaa
     8701 ttagacgaag tagacagcgc aaacgtaatc gtaacaaacc ggaatgccta tgttgcagtt
     8761 gttttacaag atggaacaaa tggaaaggta acagaccgtt tggaaaagaa gattgcagat
     8821 caagtaaggg cgacagactc ggatattcag gaggtatatg tatcagcaaa tcctgatttt
     8881 gtgaaccgaa tgaaagatta tgaaaaaaga attaatgaag gtgctccagt aaaaggatta
     8941 tttgaagagt ttactgtaac agttcaaaga gtatttccaa atgctcgtta aataagagcg
     9001 attgaacgca gcaagttaat ctactatgtt ccagcaaaga gaaacctcct tataaattaa
     9061 ggaggtttca tatgcgttta tttctcaatt gaatgccata tacattataa taattatttt
     9121 acgttcgact tttttagtta ccgtcacagc aaagttaata caatatattt ctcgttcagg
     9181 aggaaatatt gcatctatct aaaaagtaag gagacaagtt ttatggacta taaaatgttt
     9241 agaacaatca atcaactggc tggtcgttat tctaccatag atatgctgat gatattgatt
     9301 tcaaaaaagg ttcgttatgt atttatgttt gtattgattt ttatgtggtt tcgaaactat
     9361 tcgcaaaaaa aagtgacaat atatgcagta acatcttcgg cctttacttt atttattaac
     9421 acgttgatta aatgttttta ctttaagcct cgcccattta taaaacgccg tgtcggcata
     9481 cttattcctt caaaaatgga ttcttcattt ctaagcaaac atacgctgct tacttttgcg
     9541 gtatctactt ctatctttct tcatgaacgt gtgatcgggt cagttatgtg gggactggct
     9601 ttgttaacgg ggttctcaaa gatttgggtc ggacatcatt atccttctga tatcatccga
     9661 agtgccttta ttggcagtgt gacaagcatc accattgaca aaactgcacg tttctttaat
     9721 tcttttattc gtctataact gacataagta ttagtctaag attttatagt aaaaaaacag
     9781 aatatagcta gagaaattac actgtaacat aaaaagactg gctttaagtt ttttgttctt
     9841 cttttcaatt agtcagaatt gccaaattgt aaactaaaag atttataacc aaaaagcctt
     9901 cactcaaatg agcgagggct tctcttttct accagaaaac agaactggat tcgttaaatg
     9961 gacattttag ccgttgaaaa tagcttcatt ccctccttac ttagctttgc aaactcccct
    10021 ttaaccaagg gcgaggtcgg taggggccgg tcggaatttg gattagactg gtttttcctt
    10081 gttgctccat tttgtagatc tcgtcacaca ggttggcatc aaatccgagt agtgggtgtc
    10141 ctcccatatc gatggccgac gccgctaaca gtaatcgttg cacgagcata cctgcttcca
    10201 tttgctgaat acgatagcct ctgtatccca gttccgatat gaagtgatct ttatcccctg
    10261 ccacatgaaa gcagaatggc acttgggata aattcacatt ccctacaggc attccatatt
    10321 gcaaactgag tcgatgatca ccgagatcta cctgtcgtaa cgcatgatta gcactatcat
    10381 aatgataggc tccatcggga ataccttcaa tattattcaa acagacatac agtgagacac
    10441 ggggctcgtt cttcttatgt gcttcatcca gatcatttcg atacaagtac gccgacgttg
    10501 cttcctgcag taaagtggcc aactgcaatt gacttacctt tccaaaaatg aaatccatgt
    10561 ccggtgaaaa tctcttttga caaaccgaag ctagatcata tgataatcgc ttcatgtgag
    10621 gaagagtgac cacttgactc ttacaattca ccttctccct cacctttatt tgccgaaacg
    10681 attgctttga ttctagcatg gacgcttcat tcatcttctt taacatcgga aacgctttga
    10741 tcctctgtga tcggacgtag tgattatttt gaatgactgg caactctcga cacagttcga
    10801 tagcagaaac aggctctttc ccaccccgat tagtaaacca acttgtaggt tccactgtta
    10861 gagggataac tgcatataca ctctcctctt cttcgtttag tccaagcaga tggttgatcg
    10921 cccgatctag atattgaaag tacaccccag aagcaaaacc aaaccgtttt gctacttcca
    10981 gtaactgtcc aatcagcacg ccagcatcta gcccttgtag acgataagca aagttattgt
    11041 atttatagaa gtttttccaa aacattgtcg acacaaaaaa cgtaccaaaa caagcggaca
    11101 catcacagcg attgccaaga gcctgggcta tatatgaatc gaagttacct tctctcaaca
    11161 gtaccaagcg atggtgtgct acatcataat ggtacatccc aaccggcaaa tcctccgtct
    11221 tcagatatac gtacaattcg tttgggtaca acgccccgcc agaaggaaca aaacgccgat
    11281 acgactgcat tagttccggc tcttgatctg tagtagaaaa ggctgactgg gaaatttgag
    11341 taagaccaaa tacataccag agaaaatgac tcattctctg aaggttaggc tgttctggcg
    11401 ctgcccattg ttcaagcgac agcggtactt ccagagataa tgggaaaacg ggcaagtcac
    11461 ggtagagctt atacggaagc ggggcatctt cccaatccac ttcccagtcc gttgggcttg
    11521 ccttatcaat gtcaaaatgc agattgtaca gaaatgtctc gagacccatc ctcttaccct
    11581 cctagttacc gcttatggaa acggatgcgg atgtggatta agctgttcaa atgtcagcgg
    11641 tttcttttta tatccaagtt ccattggtac ccgcagcact ctctccagtc ctgttactct
    11701 cgtaaggtga tgtccgaatg tcattggcaa cattcccgga atcagcactt taacacaata
    11761 cagtccgttt cgtttagttt ccggtgtcga ctgatccacc acaatcacat cgagattcaa
    11821 tcgacgaaac ttctgaagaa tgtcctgtag atcatcagtc agatctgcag aattcgattt
    11881 ccacttgaat tcctcagcaa acgatcgcaa tggacgatta tcatctagca aaaactgtag
    11941 gcgctcttgc gcttgcggca aaccgtacag catgccatga tcatccatct tctgcaccaa
    12001 ggaagaatct tgcagcattc gcacaaactc ctcctggttc gtctctaatt tctcatcaag
    12061 cgtcagcatc atggcagcca gctcgtgaat cgtgcttttt accgcccgta ctggatcaag
    12121 atgagctcca gctgcacaga tgatattcaa accctttttc tttctgtttt ttgccatcgc
    12181 ccaaacgctt ggaattccgt gctccatcgt cgaattataa aagtgtagat catatccccc
    12241 tattgcccgc acacgatcga tcatcagctc taattcttga tcgttagcgg aataaggatc
    12301 aagacgcggg aggggcaact ctgcgtacca agtcattaag aacgaatcac gttctaccac
    12361 ttccaaaata ccgtagaaaa tggcttcttc caaacttccc cctaatgcgc atccgttgga
    12421 agtttcatag acaaaccctt ggccacatcc caaactgtaa taggcaagta actcaggaac
    12481 caaaattgga cgttcttgca aaaaggaata gccccatacc cattttatcg gacggtcagg
    12541 gtgaaactgt tcaaatggaa aaccaggctc ggcataccgt tccttcgcgt gcactcctac
    12601 ttcaatagga ttgatcgctt gatctttcag attacgataa ctatcatatt cgacggttcg
    12661 ttttccacga ggtgtcatac cgcaagaccg ttccaatccc tccaaaatag cagttaactc
    12721 gcttaccgca tatgaatgag tccgtcctgc tactccttcg tctcctgaga ataacggcaa
    12781 atttacaact acatcagcaa aaggcgggac aaggtcatac atttttccat tcaaaatgcc
    12841 catccgttga tccaaatagt ctttaaccag gactttattt agatcgtcca tcgaacggca
    12901 gcggtaacta tcagtaatct ttgggcttga ttttaacgaa attctggccg cagctggtga
    12961 atcgtcaggt aattggctgc aaccaggaca taatggatcg gacaaaaaag tatgccatga
    13021 actctttaat gttttcagat taattaaaca tacctgtcct tccgagtgca cctcatcacc
    13081 ttgcacgatc ctctgtacct ccctcccaag caggcaggcg atctgcaaaa gccccaagct
    13141 cgatgcccac gcgtcacgcg ttactccccc gtccgcagcc agctgctgtt gcatttccca
    13201 catctcttta cggtcacgtc ctgccatgag atgtcgtatg tccgcacatc gggagcaccc
    13261 tggtgtatcc gaaccaacta gcggtccgat cacgccttct ccaaatgaaa cgaagcctcg
    13321 cagccatcgg atgccggttg gacgcaacac ctcttctgct ttttgatgaa gagaaggatt
    13381 ccaagcatca tccaacacta aaactaaatc agccgcttca ggtaattctg cctcgaaatc
    13441 aatatgacga actacctggt attggtctga caattgttca tacacgtggt cagctagcat
    13501 tccttctcca ataatcacta cgactgcact cacttggatt cctcctctcg tagcaacata
    13561 ccatacactc ctaccagttc ttttttgcaa aagggctcca gtgctagttc gaaaaacaag
    13621 agtcgcttgc cattctgttc taaaacctgc atcgcggacc gcaagacttc agaatgtgat
    13681 atctcttcac tcttttggat tacaaggctt tttggtacct tctctaccag aaacacagac
    13741 gaattcggca gcacttgtgt cgcttgattt tctttattca taagcgcttg ttgtaatgct
    13801 ttttgcaacg ccattgttgt attcaaacct acactgccat accagcgatc attcgtaccg
    13861 acccatacca cagggaagcc ggatacttcc tttcccaaac ctataatcgg tgcaccctgc
    13921 gtcacggtca gtgcctgtaa acaataccgg caatgttcat cttctacatc acttacctgc
    13981 acccgagaga caatattttt ctgatcgatc agctgtttgc tcagctcctc tgttaaacac
    14041 ttttgcaatc cacggcaaac gccctctgca attgtttctc ccgctccaac cccaacaaat
    14101 tcctcagatt ctacgataac cctctctgct ttctgttgtg aaggaagagt cgtaaggaac
    14161 gcatcgacca ttcttgatac atacgcttca actccagata gaccagcttc tttccgtgcc
    14221 ttctcatgtg tcagttctgt acagaccatg cttggcaata gctcagcagg ccccttcgac
    14281 aacggatcaa ccacctgaac gtggcactgc gctaacggta actgctttaa atcctcttct
    14341 tctaaaatgt ggaaaatgcc tgattccttt gatgttaact gactaaagta cagaagcaac
    14401 ccgctcgatt cccctctgct cgaactctgc ttgagccgca aatcaaaatc ttgaacccat
    14461 tcagctgtaa cacgtccggt cactagcgga tgaggcataa acgaatgcca atttccttct
    14521 aacgtatcca gattaagcag gaagaattga ttcttctgtt ctgattcagc aactctcgta
    14581 acgtttttaa acaattcaaa tacgatcaca ttagccaaca tcgctcctgc cgtggaagtg
    14641 aagctaggta attgctcgtc attcctaaac acagattcgt gtatgctgcg ccatgcagac
    14701 tcccaacatc cttcagagcc tggatgaacc aaaggacctg ccaaacccac ttggtgcaaa
    14761 aatatagcag ggagtaacac ttttttctct tccctacaaa tcttatgaag agctcttagt
    14821 tcctctacat cgccttcctg cgacacatac aaaattgaat caaacggttg cacaatctcc
    14881 ctccaagaat ttcccccgtc cttttcaagg atgacttcct ctattgctac ctcggggtcc
    14941 gtttttcggg catgccctac caatccttct aaccgcagct gattggtcgg tacagagtcc
    15001 gttatcatca catggaattt agacaatcca gactcaatca atgaagaaac caacgaaaca
    15061 aaaaaagagc cagagcctat cgccaacact ctggcctggc ggtaggcttg aaaacggtac
    15121 gcagctgaat ctccaaaact ttctaaaaat tcaatttgag aagcatactt tttaaggact
    15181 ggatccgcca attgatgcgg acggtcttga cttgcatccc gagcaaaccc gttttgatac
    15241 agcacttctg caatttcata tacacgttct cgatatggac ccggcaatcc gtttgttaaa
    15301 ctctccaacg tatactctcc attgaacatt ggtatcagct ttttcaccca ttgatctatc
    15361 atactgcctt tcatatggaa cgaacttata ttatttcgaa aatacacacc gctgtttgga
    15421 tcagggagaa aaaaagtatc ccttttcact ttcaaacgca tagaagggtt caaatttgtc
    15481 attccgctcc tccttatccg tgaactgttc tcaactctaa tagcactatt ttccatttcc
    15541 actatcatcc tatgtactgt aatttgtctc ttatgtctaa tcttttagag aaaagcccct
    15601 gcaacttatg caggggcttt ccttcataga taacgatgtt ttttattcga aaactagaat
    15661 tatcagccgc cgcaacgacc tccgccacaa cgacctccac aattgccacc acaacggccg
    15721 ccgcaattgc caccacaacg aaaacagttg gagcaacgaa aacaattaaa gcaattaaag
    15781 caattaaagc aggtaaaaca gctaaaacaa ctaaaacatc ggaaaaaaat cccgaattgt
    15841 cgatcttgat ccatattgtt tggatcccaa ggaatggctt gattcgcttg gaaatcacca
    15901 agatccaaca tttgaagttc attttggaaa ttattcactt ttcatacctc cgtatttaaa
    15961 ttaacaaggt gtgctaacac cataaaagag aagcagaatg aaaacaactg tataacaaga
    16021 ggctcaaaca atacttcgaa tacccccctc aacaaagtat gaactctgct tgggtgttgt
    16081 tactgattca aatacctatt ttgattcatt ttttaaatta atacctgatc tcgatgcatg
    16141 aaaagaagca tagttcattg gacgagcgaa acgatttaat gatgctcttt ccaaaatgac
    16201 cgtaatccca gctttactat ttttacagat actaatgcac gcttccatct ttttctactg
    16261 acattatgtc gcagacagaa tgggccaaca caagggttaa accctcctgc attaacaata
    16321 ggtttatttg ttgagatgta attaaatgat ttctagcctc gagagcttta aaggaagaga
    16381 actatttgga aaaatagttc tgcaacagaa gttgtagaag tactattcag aaggctttta
    16441 aaatagaaaa aactgataaa gcagtagcta aaaggttgca tgataattat gtttctattt
    16501 atcatatgca caaataaatg aataagaaaa aagcacttac cctttagaga ataagtgctt
    16561 tttcactatt tattgattta acatccttag cgttacatgt ttcgttccta ctttcagttt
    16621 ttcgccgtct tctgtatctt cagtgaaaca aagactgttt agcagtaagt tctcttgcaa
    16681 caagccttca aagctagtga cagcttcctt cacttccgca tcgccgctaa gttccaaatc
    16741 aatgcgtaaa ttcaccggca aatccaactt tttacgatag tcctgtactg ctcgaatgac
    16801 ttcacgagct aacccttcct gcaccagtgc ttctgttaac gcggtatcta acacggcggt
    16861 atacatgccg tttgatgcca ccgcaaaacc ctcttttggt actttttcaa ccagcacatc
    16921 agctgtttca agcgttagct tttcacctga tgggagcgtg accctccgct caccttgttg
    16981 aacaaaatct ttcgtttcat ctgctgaaag atttttcaac gtttgattca ctgcattaac
    17041 ttgttttcca aacttcggcc ctgcctgttt aaagttaagt tttaacacgt acgagacgag
    17101 attttcatca tcttgctcca cgttaaattt ctttacattt aactcatctt tgatgacatc
    17161 acggtacgca ttccactcga tatcttcatt cgtcacgaca agagacaaac tccgtaaagg
    17221 ctgcttcacc tttaacgaat gcgtatttct gatgcttcgt cctagttcca ctacctgcaa
    17281 gaccgctgcc atttctcttt ccagcttttc attcactttg ccttcattat aaacaggata
    17341 gtctactaaa tgaacgcttt ttcccgtcag attttcatga atatcatccg caacaaacgg
    17401 agtaaacggt gctaacaact gactgagcgt gactaatact tcgtgaagcg tatcataagc
    17461 tgctgctttt tctccgtcca ttccctctga ccaaaaacga tcgcgggaac gtcgtacata
    17521 ccagttgctt agctcttcaa tgaatactgc gatttcacga gccgcgcttg taaacccgta
    17581 atcttcaaga tgtgccgtta ctcgtttgac cgtgctgtgc aaacgtgaaa gaatccattc
    17641 atccaatttt gtttttttca attcatacgt ttgctccggg tcatagccgt ccagctttgc
    17701 gtacaacacg taaaagccgt acacgttcac tagagtatca ataacttttg acttcgcttc
    17761 ttgcaccacg cgctctgaaa atttcttcgg gttccaaggc gcactgtctg ctaaaagcgc
    17821 ccatctaagc gcatctgcac caaatgtatg aataagatca acagggtcca gcgcatttcc
    17881 tttactttta gacatctttt gaccgttttc atctaacacg tggccaagag acagaacgcg
    17941 cttatacggt gcttttcctg taaatagcgt tgaaactgcc atcaagctat aaaaccagcc
    18001 ccgcgtttga tcaattcctt ctgcgattac gtctgctgga aactgctttt gaaacagttc
    18061 gctgttttca aacggatagt gatactgcgc aaacggcatt gagccgctgt caaaccaaac
    18121 gtcaattact tccgccgttc gcttcatttc tccgctgcag acgggacacg ttagctgcat
    18181 gtcatctaca taaggcttat gaagttcaat gctgtcatca acgaaatgag acgcatgttt
    18241 ttgaagctct ttgatgcttt ttggcgctac ttgatgctga catttcccgc attcccatac
    18301 gttcagcggg gttccccagt agcgttttct gctgatgttc cagtccacca tattttctaa
    18361 aaagttgcca aagcggccgt gcttgatatg atccgggtac cacgtcacgc tttcgttgtt
    18421 tttcaaaaat tgttccttta acgccgtcgt ttggataaac cagctttcat ttgcgtaata
    18481 aagaagcggc gagtcgcatc tccagcaaaa cggatagctg tgctcatgct tttctttatg
    18541 atacagcacg tcttgattcg ctaaatagcg cacgatatca acgtcgcagt ctttcacaaa
    18601 acgtccttga aacggcggca cttcagccgt gtactgtcct ttttcatcca ccacgttcac
    18661 aaacgaaaag ccgttttctt ttaccactct gtaatcatct tcaccgtatg caggtgctaa
    18721 atgaacaact cctgttccgc tttgatccgt tacgtaatca gccgtcacca cttcatgccc
    18781 tttttccact ttcacaaaat taaacggcgg ctcatacgac atccctttta actcatttcc
    18841 tttatgttga gataaaacgg tatactctcc ttttaacact ttgtctgcga gcgcttctgc
    18901 cactatatac acgctgtcgc cttgctcagc gcgaacgtag ttcatctctt catgcaccgc
    18961 aagcgccacg tttgacggca gcgtccaagg tgttgttgtc cagcctagaa aatactcatt
    19021 atcgcggttt ttcactttaa atttcaccgt taccgttaaa tcttttacat ctttataccc
    19081 ttgcgctact tcatgcgaac tcagcgacgt ttgacagctc gggcagtaag gtgatacgcg
    19141 gtggccttta taaagaagtc ctttatcatg aatcgtgcca agcacgttcc atacactttc
    19201 aatgtatgaa ttctccaagg tgatgtaagg gtcttccata tcaacccaat agccaagctg
    19261 ctccgtgaac gtgcgccact gcttttcata cacaaacaca ctttccttac acttgttgat
    19321 aaaagcttct acgccgtatt tttcaatgtc atgcttccct gatattccga gctgcttttc
    19381 tacaccgagc tccaccggca gtccgtgcgt atcccagcct gcttttcgaa tcacttgatg
    19441 ccctgtcatc gtcttataac gagccaccac gtctttaatc gtccggccta gcgcgtgccc
    19501 aacgtgaggc aaaccgtttg ctgtaggagg cccttcataa aatacaaacg aaggatgccc
    19561 ttctcgattt tgaaccgact gctgaaacac atttcctttt tgccactgct gctggatacg
    19621 ctgttcgcgc tcttgcgaag actcccttac attcacttct ttcatgtgat accactcctt
    19681 ttaaagttaa aagcacacaa agaaacccgt ccctatgact agggacgggt tttaaaccgc
    19741 ggtaccaccc tggcttctat tgatccgttc atcaatagca ctcagcaacg tacaatcata
    19801 cgcgttcttt ttaacggtag actaccgttc aaacttactt atcgttcagt ttgacttctc
    19861 agagaggata ttcccctgcg gcttgaacac cggctttcag ctatcaccgg ctctctgtgg
    19921 aacaaacttg cagcgtactg attctcttca acgaatttgt gtgcttttat tagtagctat
    19981 tgtatgcgtt ttggaaggga atgtcaatgt tttgaaatac ttattgagat caaaaggttt
    20041 agatctaggt tattttgttt ctgcacttaa catttgatcg attttattac acgctgttat
    20101 cccgttctta tctttccatt cagaagttcc actgcttctt cgctgtgtca caaacactgc
    20161 cgcagctgag atagaagaaa aaatttgatc ttgtaccagc acgtatctac catcttttat
    20221 ttctaataca ccgtttgcta agaaagtatt aatatggtct tgctgccttt taagtttagc
    20281 tccttctagc tgctgttcgc tcgcaagcaa agctccttta tagacaagaa atccatcgct
    20341 aacatatttc cccgtcgcat acgcatctcg gcgtttacaa tatagaacgt cctctactat
    20401 tactgatttt atatcttttg acaaatgtgt ctcaacttga acaacctttt ctatcgcttg
    20461 ctctgcttca atctttggta tgtcaccaga ctgtacagct ccgctttcat attctattcc
    20521 atttgaagca tccgcaaaaa ttgaaaagcc taatccacca agtaaaactt taataacatt
    20581 aaaaatatct gtcaggtcat ctcgtctaaa ctcacgtaca aacggctttg tcggaacggt
    20641 ttgattaata tcatatgtac cagagcgcat ggctgctaga taagaaatat gttctaagta
    20701 ttttacatca actttatcta attgatcttg agaggcatta gacacaatta acacggccac
    20761 atcccaaaaa cttttacctg ttgatggact agcatgctgt cttaaacgtt catatcccac
    20821 ttctgcctct ccaatatatg cctctttatc ttctccaaat aaaaaataaa tgccgggctt
    20881 ttctacttcg ctttcaccct ttaaatcttt caaactattt ctgggaatga atacagcctg
    20941 tattgttgta ttcggcacct cagatacttt aatcccgttt ggatcatcat cgtaaaacca
    21001 agcctgtatt cgtttcgcgc cgctttttcg tagcatcttt cttcctccgt ttatatcttc
    21061 ttgagcgtat tttaactgac attacaatat gtaaatcact tcctaattat agacgcagca
    21121 atctatcatt cacaaaaatt aatttatatc acctgcttga tatctagcag gtcccctaaa
    21181 tacttctcta acatgccacc caagaaaatc ttcgctcggt tgatacgccg gatgaatagg
    21241 atctctaagc ttttgcccgt gaaatttcat aagccattct tcaaatccat tcgtcccgtg
    21301 cgcttgagtt gccactaaca gctcattatg atcggaaaaa gtaaaaactc cccgatcaaa
    21361 taatttatga tgcattgaac ataacgcgat tccgttactt tcaatatctg gccctcccgc
    21421 ttgatgccac ttaatatgag cagcctccac gccaactaaa ttgtttccaa gacgaacgtt
    21481 aaacccacaa acagcgcagc tatatccgta agcttgaaga attttctctc gaaactttgg
    21541 atctcttctt cgctttaact gtgtttcaaa atccaagcct acggctctta atatatcttc
    21601 atgaattgta tctggaaaat gctcatttaa taaaaattgt gctgcgtctt gaagaagcgt
    21661 aggatcactt tcaaaaaggt tataaacatc ctatctaaaa ccgcctatta tatttttact
    21721 cagcaaatat ttatctgtaa agctgcgctt atcaacttct tcgcttagct cccatattcc
    21781 atctcctgtc aaacgaacaa aaggatgctc cggatgatag gaactccgag aaggtccaaa
    21841 ctccataagc agctctttca aaggaatttt cacctctcta tacggcaggt gcatttgctg
    21901 ttttgcctgt agctgaccta gggcgtacag tattaacaat ggtttgtgcg gagctctttg
    21961 atctcttttt ttccagatgt ttaagttttt tattttttga agtacttctt ctctgttcat
    22021 aagcttgctt taactcccat ctataaaact atttaaaacc ttagagctaa gaccgttttt
    22081 gaaaaagtat taataaatgt aagtataata actaattcta ttatatgaca ccattggatg
    22141 atcaaggggg ttttatttac aggggcattt ataaaacgct actttataac actttcttat
    22201 ccaagttgtt ttgttcaaag tattcttttt tcatatcttt tctgctttta aaacttactc
    22261 gttctgtgtc tttaatacct acattaaata atctctcaca aagaaaaaag ctctccaaga
    22321 aacatatagg agagctttta aaggttgcat acattttttt atcgttggga ttttctatac
    22381 ccagctgcct gtgcatccgc ttctgaacag aaccaaacaa tattatcttg agttctatca
    22441 taataagctc cgccaggtac gtggtaaatt ttcgagtttt tattgccttt gatttgaccc
    22501 gaacaagaca tgttagactg ttgatcatca ctcggatcat tttcaaatgg cttataattt
    22561 ccactgctgc tagtagaact gctagttgta gcctgttgac tagctgcttg ttgttgagct
    22621 ttacgctctg cttcttcttt tgccgcttgc ttctcagctt gtcgttccgc ttcttctttt
    22681 gcggcttgct cttgagcttt tcgttctgcc tcttcttttg ccgcttgctc ttcagctttt
    22741 tgttttgctt cttcttttgc ggcttgctcc tcggcttttc gttttgcttc ttcttttgcc
    22801 gcttgctcct cagcttttcg ttttgcttct tcttttgccg cttgctcctc agctttttgt
    22861 tttgcttctt cttttactgc tttatcacta tcattctttt caactttttg cttgctgcta
    22921 tcagcaccat cttttttaga tgcaacagtg acactgtttt gcgaagaact tacttgagtt
    22981 gaggcagggg tagaagttga ttctccatct gtaaaagcta cagcaataaa aaaacaacta
    23041 aaaattaaat atagataaga aaataataca cgttttcttg ttttgacttt aaatttaggc
    23101 aatacccact ttggttttat taatccaata agtaaaccta tgatacttag aaaaagaacc
    23161 aatgaagcta attccataat aaaattatga gtagctgctg gtaataaggc atgtaatatg
    23221 aataaaagaa ttaaggtgta aatagtagaa gccataaaca ttttccaact ggtctgtgaa
    23281 cgatatccta atactttagt ccagacgggt ctttttacta cgttaacttc catagaagaa
    23341 tggttgcgaa taacttgctc tacttccttt ccttttactt ctattgtaat atccctattt
    23401 ttatcatgac ctacaaatgt aaatgctgat tttgtaatgc tatggttaat tgtaacgcta
    23461 gagaaatcag accattcata ccgctcaatt aacattaaat ttcgttcagc gttcttgtta
    23521 aattcataaa aat
//
