GCF_023716685.1 - 8 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP072679.1 (Ferrimonas sp. SCSIO 43195)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	terpene-precursor	1,097,997	1,118,884
Region 2	RiPP-like	1,280,245	1,291,075
Region 3	arylpolyene	1,627,593	1,671,175	Low	APE Vf	other:other
Region 4	RiPP-like	1,975,296	1,986,255
Region 5	NI-siderophore	2,260,399	2,290,780	Medium	desferrioxamine E	other:other
Region 6	hserlactone,lanthipeptide-class-iv	3,474,109	3,511,753
Region 7	RiPP-like	3,534,258	3,545,097
Region 8	betalactone	3,737,411	3,768,396

NZ_CP072679.1 - Region 1 - terpene-precursor

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Location: 1,097,997 - 1,118,884 nt. (total: 20,888 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: acetyltransferase

J8Z22_RS05385: Chloramphenicol acetyltransferase

smcogs: SMCOG1156: Chloramphenicol acetyltransferase

Hydrolases: hydrolase

J8Z22_RS05315: HAD-superfamily hydrolase, subfamily IA, variant

smcogs: SMCOG1115: HAD-superfamily hydrolase, subfamily IA, variant

Ligases: synthase synthetase

J8Z22_RS05320: 1-deoxy-D-xylulose-5-phosphate synthase

smcogs: SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase

J8Z22_RS05325: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001361.3	0.50	terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0002283.2	0.50	terpene	sodorifen	Serratia plymuthica
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0000884.5	0.43	other (other)	3-methylarginine	Pseudomonas syringae pv. syringae
BGC0001075.5	0.40	PKS, terpene	aurachin RE	Rhodococcus erythropolis
BGC0001594.3	0.40	other (other)	fischerindole L	Fischerella muscicola UTEX 1829
BGC0000665.5	0.39	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0001605.3	0.39	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0001501.5	0.38	other (other)	ambiguine P	Fischerella sp. TAU

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001361.3	0.50	terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0002283.2	0.50	terpene	sodorifen	Serratia plymuthica
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0000884.5	0.43	other (other)	3-methylarginine	Pseudomonas syringae pv. syringae
BGC0001075.5	0.40	PKS, terpene	aurachin RE	Rhodococcus erythropolis
BGC0001594.3	0.40	other (other)	fischerindole L	Fischerella muscicola UTEX 1829
BGC0000665.5	0.39	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0001605.3	0.39	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0001501.5	0.38	other (other)	ambiguine P	Fischerella sp. TAU

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor		FPP	C15	acyclic	PP

Genes with terpene domains:

J8Z22_RS05325: PT_FPPS_like

Domain 1 (31 - 293): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:: IPP, DMAPP → FPP

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (1):

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 20.34 out of 29.38

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description

NZ_CP072679.1 - Region 2 - RiPP-like

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Location: 1,280,245 - 1,291,075 nt. (total: 10,831 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002669.2	0.22	ribosomal	TVA-YJ-2	Streptomyces sp. NRRL S-87
BGC0001387.5	0.20	other (other)	nucleocidin	Streptomyces calvus
BGC0001586.3	0.18	saccharide	EPS273	Pseudomonas stutzeri

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002669.2	0.22	ribosomal	TVA-YJ-2	Streptomyces sp. NRRL S-87
BGC0001387.5	0.20	other (other)	nucleocidin	Streptomyces calvus
BGC0001586.3	0.18	saccharide	EPS273	Pseudomonas stutzeri

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 21.28 out of 26.33

Confidence: medium

VqsM

Description: Regulator of quorum-sensing signalling systems
Species: Pseudomonas aeruginosa PAO1
Score: 18.09 out of 20.47

Confidence: medium

AbrC3

Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 18.07 out of 18.16

Confidence: strong

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 16.86 out of 18.57

Confidence: medium

CRP

Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 16.67 out of 19.26

Confidence: medium

AbrC3

Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 17.71 out of 18.16

Confidence: strong

Additional weak hits (5):

HexR

Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 22.46 out of 31.73

Confidence: weak

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 17.88 out of 21.84

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 23.04 out of 32.74

Confidence: weak

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 19.57 out of 26.33

Confidence: weak

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 20.64 out of 33.14

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
ANR	Anaerobic transcriptional regulator
AbrC3	Antibiotic production activator
CRP	Cyclic AMP receptor protein
ToxT	Regulator of MSHA biosynthesis
VqsM	Regulator of quorum-sensing signalling systems

NZ_CP072679.1 - Region 3 - arylpolyene

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Location: 1,627,593 - 1,671,175 nt. (total: 43,583 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

J8Z22_RS07900: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: acyltransferase halogenase

J8Z22_RS07825: acyltransferase

smcogs: SMCOG1141: acyltransferase

J8Z22_RS07880: conventional flavin-dependent halogenase

halogenases: conventional flavin-dependent halogenase
smcogs: SMCOG1119: halogenase

Isomerases: isomerase

J8Z22_RS07950: isochorismate synthase

smcogs: SMCOG1018: isochorismate synthase

Ligases: ligase synthase

J8Z22_RS07845: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

J8Z22_RS07855: polyprenol-monophosphomannose synthase ppm1

smcogs: SMCOG1123: polyprenol-monophosphomannose synthase ppm1

J8Z22_RS07890: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

J8Z22_RS07905: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002341.2	0.75	other (other)	3,5-dibromo-p-anisic acid	Planctomycetales bacterium 10988
BGC0002608.2	0.75	NRPS, PKS	ochratoxin A	Aspergillus steynii
BGC0002008.3	0.63	other (other)	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.5	0.62	other (other)	APE Ec	Escherichia coli CFT073
BGC0001160.5	0.60	PKS	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0002276.2	0.59	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0000837.4	0.51	other (other)	APE Vf	Aliivibrio fischeri ES114
BGC0002510.2	0.50	PKS	youssoufene A1, youssoufene B1, youssoufene B2, youssoufene B3, youssoufene B4	Streptomyces sp.
BGC0001895.4	0.50	PKS	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0002000.4	0.49	PKS	setomimycin	Streptomyces aurantiacus JA 4570

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002341.2	0.75	other (other)	3,5-dibromo-p-anisic acid	Planctomycetales bacterium 10988
BGC0002608.2	0.75	NRPS, PKS	ochratoxin A	Aspergillus steynii
BGC0002008.3	0.63	other (other)	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.5	0.62	other (other)	APE Ec	Escherichia coli CFT073
BGC0001160.5	0.60	PKS	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0002276.2	0.59	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0000837.4	0.51	other (other)	APE Vf	Aliivibrio fischeri ES114
BGC0002510.2	0.50	PKS	youssoufene A1, youssoufene B1, youssoufene B2, youssoufene B3, youssoufene B4	Streptomyces sp.
BGC0001895.4	0.50	PKS	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0002000.4	0.49	PKS	setomimycin	Streptomyces aurantiacus JA 4570

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57

Confidence: strong

Additional weak hits (8):

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 19.44 out of 27.78

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 17.75 out of 28.14

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 19.88 out of 28.14

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 19.91 out of 28.14

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 18.93 out of 28.14

Confidence: weak

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 20.53 out of 30.25

Confidence: weak

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 19.50 out of 26.33

Confidence: weak

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 19.43 out of 25.88

Confidence: weak

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS substrates

TFBS Finder

NRPS/PKS substrate predictions

J8Z22_RS07845: X

AMP-binding (118..330): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: LEIAHQHIYGLRVAFSSGGVEIYGSTETGGIAHR
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

Link to PARAS substrate predictor

TFBS definitions

Regulator	Description
ToxT	Regulator of MSHA biosynthesis

NZ_CP072679.1 - Region 4 - RiPP-like

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Location: 1,975,296 - 1,986,255 nt. (total: 10,960 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	RiPP-like	Similarity score	Type	Compound(s)	Organism
BGC0001488.3		0.20	other (other)	4-formylaminooxyvinylglycine	Pseudomonas fluorescens WH6

Reference	Aggregated	Similarity score	Type	Compound(s)	Organism
BGC0001488.3		0.20	other (other)	4-formylaminooxyvinylglycine	Pseudomonas fluorescens WH6

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (2):

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 17.88 out of 21.84

Confidence: weak

LuxO

Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 19.20 out of 26.12

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description

NZ_CP072679.1 - Region 5 - NI-siderophore

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Location: 2,260,399 - 2,290,780 nt. (total: 30,382 nt) Show pHMM detection rules used

NI-siderophore: IucA_IucC

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase oxygenase

J8Z22_RS10765: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

J8Z22_RS10820: lysine/ornithine N-monooxygenase

smcogs: SMCOG1080: lysine/ornithine N-monooxygenase

Transferases: methyltransferase

J8Z22_RS10865: methyltransferase

smcogs: SMCOG1089: methyltransferase

Hydrolases: hydrolase

J8Z22_RS10750: alpha/beta hydrolase domain-containing protein

smcogs: SMCOG1066: alpha/beta hydrolase domain-containing protein

J8Z22_RS10860: HAD-superfamily hydrolase, subfamily IA, variant

smcogs: SMCOG1115: HAD-superfamily hydrolase, subfamily IA, variant

Lyases: decarboxylase

J8Z22_RS10825: Decarboxylase, pyridoxal-dependent

smcogs: SMCOG1180: Decarboxylase, pyridoxal-dependent

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001572.3	0.69	other (other)	desferrioxamine E	Pantoea agglomerans
BGC0001478.5	0.66	other (other)	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.3	0.64	other (other)	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0002305.2	0.62	other (other)	legonoxamine A, desferrioxamine B, legonoxamine B	Streptomyces sp.
BGC0002620.2	0.60	other (other)	fulvivirgamide A2, fulvivirgamide B2, fulvivirgamide B3, fulvivirgamide B4	Fulvivirga marina
BGC0000940.5	0.57	other (other)	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0001453.5	0.56	other (other)	desferrioxamine	Streptomyces argillaceus
BGC0002690.2	0.56	other (other)	FW0622	Verrucosispora sp. FIM060022
BGC0002464.3	0.55	other (other)	alcaligin	Bordetella pertussis Tohama I
BGC0001531.5	0.55	other (other)	bisucaberin B	Tenacibaculum mesophilum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001572.3	0.69	other (other)	desferrioxamine E	Pantoea agglomerans
BGC0001478.5	0.66	other (other)	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.3	0.64	other (other)	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0002305.2	0.62	other (other)	legonoxamine A, desferrioxamine B, legonoxamine B	Streptomyces sp.
BGC0002620.2	0.60	other (other)	fulvivirgamide A2, fulvivirgamide B2, fulvivirgamide B3, fulvivirgamide B4	Fulvivirga marina
BGC0000940.5	0.57	other (other)	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0001453.5	0.56	other (other)	desferrioxamine	Streptomyces argillaceus
BGC0002690.2	0.56	other (other)	FW0622	Verrucosispora sp. FIM060022
BGC0002464.3	0.55	other (other)	alcaligin	Bordetella pertussis Tohama I
BGC0001531.5	0.55	other (other)	bisucaberin B	Tenacibaculum mesophilum

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 18.58 out of 21.84

Confidence: medium

Additional weak hits (8):

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 15.64 out of 18.57

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 18.84 out of 29.38

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 21.66 out of 32.74

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 19.37 out of 29.38

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 18.12 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 17.77 out of 26.06

Confidence: weak

HgtR

Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 21.41 out of 36.54

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 19.23 out of 26.06

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
MexT	Global virulence regulator

NZ_CP072679.1 - Region 6 - hserlactone,lanthipeptide-class-iv

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Location: 3,474,109 - 3,511,753 nt. (total: 37,645 nt) Show pHMM detection rules used

hserlactone: Autoind_synth
lanthipeptide-class-iv: (cds(LANC_like and Pkinase) and not micKC)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

J8Z22_RS16240: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

J8Z22_RS16245: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Lyases: cyclase

J8Z22_RS16210: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002337.2	0.23	ribosomal	class IV lanthipeptide, SflA	Streptomyces sp. NRRL S-1022
BGC0000563.4	0.17	ribosomal	venezuelin	Streptomyces venezuelae ATCC 10712
BGC0002700.2	0.17	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0002111.3	0.15	ribosomal	andalusicin A, andalusicin B	Bacillus thuringiensis serovar andalousiensis NRRL B-23139
BGC0000496.5	0.15	ribosomal	AmfS	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000551.5	0.15	ribosomal	SapB	Streptomyces coelicolor A3(2)
BGC0002116.3	0.13	ribosomal	darobactin A	Photorhabdus khanii HGB 1456
BGC0000553.3	0.13	ribosomal	SRO15-2212	Streptomyces filamentosus NRRL 15998
BGC0002447.3	0.13	ribosomal	cerecyclin	Bacillus cereus
BGC0002701.2	0.12	ribosomal	paenithipeptin	Paenibacillus thiaminolyticus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002337.2	0.56	ribosomal	class IV lanthipeptide, SflA	Streptomyces sp. NRRL S-1022
BGC0000563.4	0.51	ribosomal	venezuelin	Streptomyces venezuelae ATCC 10712
BGC0000551.5	0.49	ribosomal	SapB	Streptomyces coelicolor A3(2)
BGC0002700.2	0.48	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0000496.5	0.48	ribosomal	AmfS	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000553.3	0.46	ribosomal	SRO15-2212	Streptomyces filamentosus NRRL 15998
BGC0002111.3	0.45	ribosomal	andalusicin A, andalusicin B	Bacillus thuringiensis serovar andalousiensis NRRL B-23139
BGC0002116.3	0.45	ribosomal	darobactin A	Photorhabdus khanii HGB 1456
BGC0000546.3	0.43	ribosomal	SAL-2242	Streptomyces albidoflavus
BGC0002701.2	0.42	ribosomal	paenithipeptin	Paenibacillus thiaminolyticus

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for J8Z22_RS16210

J8Z22_RS16215

Leader:

MHNVLNLQTLAVDSDAELMD

J8Z22_RS16225

Leader:

MHNVLNLQTLAVDSDAELME

J8Z22_RS16230

Leader:

MHNVLNLQTLAVDSDAELME

J8Z22_RS16235

Leader:

MNNVLGLQTLVVDSDAELME

Shared core:

WSTFSVNCNNEQQLK

Core with dehydrations:

WDhaDhbFDhaVNCysNNEQQLK

antiSMASH-DB 4.0 matches for J8Z22_RS16215

100.0%

NZ_AUDJ01000028.1and 6 others:

NZ_AUDJ01000028.1 Lanthipeptides: H598_RS26855_lanthipeptideNZ_AUDJ01000028.1 Lanthipeptides: H598_RS26840_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16235_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16230_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16225_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16215_lanthipeptide

Lanthipeptides: H598_RS26860_lanthipeptide

1

WSTFSVNCNNEQQLK

15

WSTFSVNCNNEQQLK

1

WSTFSVNCNNEQQLK

15

93.3%

NZ_AUDJ01000028.1and 2 others:

NZ_AUDJ01000028.1 Lanthipeptides: H598_RS26845_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16220_lanthipeptide

Lanthipeptides: H598_RS26850_lanthipeptide

1

WSTFSVNCNNEQQLK

15

WSTFSVNCNNE QLK

1

WSTFSVNCNNEVQLK

15

86.7%

NZ_AUDJ01000028.1and 1 other:

NZ_CP072679.1 Lanthipeptides: allorf_3502225_3502338_lanthipeptide

Lanthipeptides: allorf_69335_69448_lanthipeptide

1

WSTFSVNCNNEQQLK

15

WSTFSVNCNNEQQ++

1

WSTFSVNCNNEQQIR

15

with 4 more sequence matches

35.3%

NC_013164.1:

Lanthipeptides: APRE_RS09655_lanthipeptide

3

TFSVNCNNEQQL

14

TFS NC N +

1

TFSTNCKNSSGI

12

28.6%

NC_013164.1:

Lanthipeptides: APRE_RS09660_lanthipeptide

2

STFSVNCNNEQQL

14

ST+S NC N +

4

STYSTNCKNSSGV

16

18.5%

NZ_CP029560.1and 1 other:

NZ_JADOZM010000015.1 Lanthipeptides: I4U92_RS06525_lanthipeptide

Lanthipeptides: DLJ51_RS10415_lanthipeptide

1

WSTFSVN

7

WSTFS+

18

WSTFSIG

24

15.0%

NZ_CP067113.1:

Lanthipeptides: JGR68_RS08310_lanthipeptide

1

WSTFSVNCNN

10

WST S NC

9

WSTMSRNCGG

18

J8Z22_RS16220

Leader:

MHNVLNLQTLAVDSDAELMD

Core:

WSTFSVNCNNEVQLK

Core with dehydrations:

WDhaDhbFDhaVNCysNNEVQLK

antiSMASH-DB 4.0 matches for J8Z22_RS16220

100.0%

NZ_AUDJ01000028.1and 2 others:

NZ_AUDJ01000028.1 Lanthipeptides: H598_RS26845_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16220_lanthipeptide

Lanthipeptides: H598_RS26850_lanthipeptide

1

WSTFSVNCNNEVQLK

15

WSTFSVNCNNEVQLK

1

WSTFSVNCNNEVQLK

15

93.3%

NZ_AUDJ01000028.1and 6 others:

NZ_AUDJ01000028.1 Lanthipeptides: H598_RS26855_lanthipeptideNZ_AUDJ01000028.1 Lanthipeptides: H598_RS26840_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16235_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16230_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16225_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16215_lanthipeptide

Lanthipeptides: H598_RS26860_lanthipeptide

1

WSTFSVNCNNEVQLK

15

WSTFSVNCNNE QLK

1

WSTFSVNCNNEQQLK

15

80.0%

NZ_AUDJ01000028.1and 1 other:

NZ_CP072679.1 Lanthipeptides: allorf_3502225_3502338_lanthipeptide

Lanthipeptides: allorf_69335_69448_lanthipeptide

1

WSTFSVNCNNEVQLK

15

WSTFSVNCNNE Q++

1

WSTFSVNCNNEQQIR

15

with 6 more sequence matches

35.3%

NC_013164.1:

Lanthipeptides: APRE_RS09655_lanthipeptide

3

TFSVNCNNE

11

TFS NC N

1

TFSTNCKNS

9

29.4%

NC_016109.1:

Lanthipeptides: KSE_RS43690_lanthipeptide

1

WSTFSVNCNNEVQ

13

WST S C+++++

1

WSTISNYCHSKIE

13

28.6%

NC_013164.1:

Lanthipeptides: APRE_RS09660_lanthipeptide

2

STFSVNCNNE

11

ST+S NC N

4

STYSTNCKNS

13

22.2%

NZ_LT906439.1:

Lanthipeptides: CKV83_RS11410_lanthipeptide

1

WSTFSVNCNN

10

WST SV C

18

WSTQSVRCKG

27

18.5%

NZ_CP029560.1and 1 other:

NZ_JADOZM010000015.1 Lanthipeptides: I4U92_RS06525_lanthipeptide

Lanthipeptides: DLJ51_RS10415_lanthipeptide

1

WSTFSVN

7

WSTFS+

18

WSTFSIG

24

15.0%

NZ_CP067113.1:

Lanthipeptides: JGR68_RS08310_lanthipeptide

1

WSTFSVNCNN

10

WST S NC

9

WSTMSRNCGG

18

allorf_3502225_3502338

Leader:

MTMQHVLSLQALAVDSDADVMD

Core:

WSTFSVNCNNEQQIR

Core with dehydrations:

WDhaDhbFDhaVNCysNNEQQIR

antiSMASH-DB 4.0 matches for allorf_3502225_3502338

100.0%

NZ_AUDJ01000028.1and 1 other:

NZ_CP072679.1 Lanthipeptides: allorf_3502225_3502338_lanthipeptide

Lanthipeptides: allorf_69335_69448_lanthipeptide

1

WSTFSVNCNNEQQIR

15

WSTFSVNCNNEQQIR

1

WSTFSVNCNNEQQIR

15

86.7%

NZ_AUDJ01000028.1and 6 others:

NZ_AUDJ01000028.1 Lanthipeptides: H598_RS26855_lanthipeptideNZ_AUDJ01000028.1 Lanthipeptides: H598_RS26840_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16235_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16230_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16225_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16215_lanthipeptide

Lanthipeptides: H598_RS26860_lanthipeptide

1

WSTFSVNCNNEQQIR

15

WSTFSVNCNNEQQ++

1

WSTFSVNCNNEQQLK

15

80.0%

NZ_AUDJ01000028.1and 2 others:

NZ_AUDJ01000028.1 Lanthipeptides: H598_RS26845_lanthipeptideNZ_CP072679.1 Lanthipeptides: J8Z22_RS16220_lanthipeptide

Lanthipeptides: H598_RS26850_lanthipeptide

1

WSTFSVNCNNEQQIR

15

WSTFSVNCNNE Q++

1

WSTFSVNCNNEVQLK

15

with 6 more sequence matches

41.2%

NC_013164.1:

Lanthipeptides: APRE_RS09655_lanthipeptide

3

TFSVNCNNEQQI

14

TFS NC N I

1

TFSTNCKNSSGI

12

29.4%

NC_013164.1:

Lanthipeptides: APRE_RS09840_lanthipeptide

3

TFSVNCNNEQQI

14

T+S NC N +

1

TYSTNCKNSSGV

12

28.6%

NC_013164.1:

Lanthipeptides: APRE_RS09660_lanthipeptide

2

STFSVNCNNEQQI

14

ST+S NC N +

4

STYSTNCKNSSGV

16

18.5%

NZ_CP029560.1and 1 other:

NZ_JADOZM010000015.1 Lanthipeptides: I4U92_RS06525_lanthipeptide

Lanthipeptides: DLJ51_RS10415_lanthipeptide

1

WSTFSVN

7

WSTFS+

18

WSTFSIG

24

16.7%

NZ_CM000758.1:

Lanthipeptides: allorf_3263075_3263236_lanthipeptide

3

TFSVNCNNEQQIR

15

T+S++C+ +R

5

TYSLDCDPSGSLR

17

15.0%

NZ_CP067113.1:

Lanthipeptides: JGR68_RS08310_lanthipeptide

1

WSTFSVNCNN

10

WST S NC

9

WSTMSRNCGG

18

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

Binding sites found:

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 21.57 out of 26.33

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 21.21 out of 27.78

Confidence: medium

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 20.54 out of 26.33

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 21.99 out of 27.78

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 21.26 out of 28.19

Confidence: medium

Additional weak hits (10):

CopR

Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 20.85 out of 30.97

Confidence: weak

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 20.84 out of 29.25

Confidence: weak

MntR

Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 23.39 out of 39.62

Confidence: weak

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 20.06 out of 27.78

Confidence: weak

CopR

Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 24.05 out of 30.97

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 20.12 out of 28.14

Confidence: weak

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 19.93 out of 27.78

Confidence: weak

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 19.52 out of 25.88

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 19.39 out of 26.06

Confidence: weak

DmdR1

Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 23.27 out of 36.53

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

J8Z22_RS16215 - Class III

Cleavage pHMM score: -0.40

RODEO score: 0

Monoisotopic mass: 1742.8 Da

Molecular weight: 1743.9 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1761.9 Da N = 1; 1779.9 Da N = 2

J8Z22_RS16220 - Class III

Cleavage pHMM score: -0.40

RODEO score: 0

Monoisotopic mass: 1713.8 Da

Molecular weight: 1714.9 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1732.9 Da N = 1; 1750.9 Da N = 2

J8Z22_RS16225 - Class III

Cleavage pHMM score: -0.30

RODEO score: 0

Monoisotopic mass: 1742.8 Da

Molecular weight: 1743.9 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1761.9 Da N = 1; 1779.9 Da N = 2

J8Z22_RS16230 - Class III

Cleavage pHMM score: -0.30

RODEO score: 0

Monoisotopic mass: 1742.8 Da

Molecular weight: 1743.9 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1761.9 Da N = 1; 1779.9 Da N = 2

J8Z22_RS16235 - Class III

Cleavage pHMM score: -3.10

RODEO score: 0

Monoisotopic mass: 1742.8 Da

Molecular weight: 1743.9 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1761.9 Da N = 1; 1779.9 Da N = 2

allorf_3502225_3502338 - Class III

Cleavage pHMM score: -2.30

RODEO score: 0

Monoisotopic mass: 1770.8 Da

Molecular weight: 1771.9 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1789.9 Da N = 1; 1807.9 Da N = 2

TFBS definitions

Regulator	Description
ANR	Anaerobic transcriptional regulator
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
ZuR variant 1	Zinc-responsive repressor

NZ_CP072679.1 - Region 7 - RiPP-like

Download region GenBank file

Download region SVG

Location: 3,534,258 - 3,545,097 nt. (total: 10,840 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	RiPP-like	Similarity score	Type	Compound(s)	Organism
BGC0002046.3		0.22	NRPS, PKS	lobatamide A	Gynuella sunshinyii YC6258
BGC0001521.3		0.19	NRPS	auriculamide	Herpetosiphon aurantiacus DSM 785

Reference	Aggregated	Similarity score	Type	Compound(s)	Organism
BGC0002046.3		0.22	NRPS, PKS	lobatamide A	Gynuella sunshinyii YC6258
BGC0001521.3		0.19	NRPS	auriculamide	Herpetosiphon aurantiacus DSM 785

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 15.86 out of 18.57

Confidence: medium

Additional weak hits (1):

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 19.75 out of 28.14

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
ToxT	Regulator of MSHA biosynthesis

NZ_CP072679.1 - Region 8 - betalactone

Download region GenBank file

Download region SVG

Location: 3,737,411 - 3,768,396 nt. (total: 30,986 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

J8Z22_RS17260: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

J8Z22_RS17285: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

J8Z22_RS17310: acyl-CoA dehydrogenase

smcogs: SMCOG1006: acyl-CoA dehydrogenase

Transferases: carboxylase transferase

J8Z22_RS17315: acetyl-CoA carboxylase, carboxyl transferase,

smcogs: SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,

J8Z22_RS17325: acetyl-CoA carboxylase biotin carboxylase

smcogs: SMCOG1090: acetyl-CoA carboxylase biotin carboxylase

Lyases: hydratase

J8Z22_RS17320: enoyl-CoA hydratase

smcogs: SMCOG1023: enoyl-CoA hydratase

Ligases: ligase synthase

J8Z22_RS17300: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

J8Z22_RS17330: 2-isopropylmalate synthase

smcogs: SMCOG1271: 2-isopropylmalate synthase

J8Z22_RS17335: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002284.3	0.54	other (other)	corynecin III, corynecin I, corynecin II	Rhodococcus sp. H-CA8f
BGC0000706.3	0.45	saccharide	kanamycin	Streptomyces kanamyceticus
BGC0000131.5	0.43	PKS	pyrrolomycin	Streptomyces sp. UC 11065
BGC0000234.5	0.43	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001778.5	0.43	other (other)	showdomycin	Streptomyces showdoensis
BGC0000261.5	0.42	PKS	R1128	Streptomyces sp. R1128
BGC0000258.3	0.42	PKS	prodigiosin	Serratia sp.
BGC0000253.4	0.42	PKS	oviedomycin	Streptomyces antibioticus
BGC0000259.3	0.41	PKS	prodigiosin	Serratia marcescens
BGC0000244.4	0.41	PKS	nonactin, monactin, dinactin, trinactin, tetranactin	Streptomyces griseus subsp. griseus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002284.3	0.54	other (other)	corynecin III, corynecin I, corynecin II	Rhodococcus sp. H-CA8f
BGC0000706.3	0.45	saccharide	kanamycin	Streptomyces kanamyceticus
BGC0000131.5	0.43	PKS	pyrrolomycin	Streptomyces sp. UC 11065
BGC0000234.5	0.43	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001778.5	0.43	other (other)	showdomycin	Streptomyces showdoensis
BGC0000261.5	0.42	PKS	R1128	Streptomyces sp. R1128
BGC0000258.3	0.42	PKS	prodigiosin	Serratia sp.
BGC0000253.4	0.42	PKS	oviedomycin	Streptomyces antibioticus
BGC0000259.3	0.41	PKS	prodigiosin	Serratia marcescens
BGC0000244.4	0.41	PKS	nonactin, monactin, dinactin, trinactin, tetranactin	Streptomyces griseus subsp. griseus

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 18.67 out of 20.97

Confidence: medium

CRP

Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.26 out of 19.26

Confidence: strong

CRP

Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.13 out of 19.26

Confidence: medium

CRP

Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.40 out of 19.26

Confidence: medium

CatR

Description: H2O2-responsive repressor
Species: Streptomyces coelicolor
Score: 20.57 out of 25.31

Confidence: medium

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 16.86 out of 18.57

Confidence: medium

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.77 out of 23.79

Confidence: medium

Additional weak hits (8):

RicR

Description: Copper-responsive regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 25.04 out of 32.93

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 19.12 out of 26.06

Confidence: weak

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 19.52 out of 27.78

Confidence: weak

HypR

Description: L-hydroxyproline utilization repressor
Species: Streptomyces coelicolor
Score: 18.94 out of 22.40

Confidence: weak

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 22.18 out of 29.25

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 18.78 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 19.38 out of 26.06

Confidence: weak

DmdR1

Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 22.35 out of 36.53

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
CRP	Cyclic AMP receptor protein
CatR	H2O2-responsive repressor
CcpA	Catabolite control protein A
IolR	Regulator of the inositol catabolism
ToxT	Regulator of MSHA biosynthesis