LOCUS       NZ_CP072679            30986 bp    DNA     circular CON 26-AUG-2024
DEFINITION  Ferrimonas sp. SCSIO 43195 chromosome, complete genome.
ACCESSION   NZ_CP072679
VERSION     NZ_CP072679.1
KEYWORDS    RefSeq.
SOURCE      Ferrimonas sp. SCSIO 43195
  ORGANISM  Ferrimonas sp. SCSIO 43195
            Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
            Ferrimonadaceae; Ferrimonas.
REFERENCE   1  (bases 1 to 4795900)
  AUTHORS   Tang,K. and Wang,X.
  TITLE     Antagonism between coral pathogen Vibrio coralliilyticus and other
            bacteria in the gastric cavity of scleractinian coral Galaxea
            fascicularis
  JOURNAL   Sci China Earth Sci 63 (1), 157-166 (2019)
REFERENCE   2  (bases 1 to 4795900)
  AUTHORS   Tang,K. and Wang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of
            Oceanology,Chinese Academy of Sciences, 164 Xingang West Rd,
            Guangzhou, Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023716685.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 05:47:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,431
            CDSs (total)                      :: 4,267
            Genes (coding)                    :: 4,241
            CDSs (with protein)               :: 4,241
            Genes (RNA)                       :: 164
            rRNAs                             :: 10, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 131
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 26
            CDSs (without protein)            :: 26
            Pseudo Genes (ambiguous residues) :: 0 of 26
            Pseudo Genes (frameshifted)       :: 7 of 26
            Pseudo Genes (incomplete)         :: 17 of 26
            Pseudo Genes (internal stop)      :: 5 of 26
            Pseudo Genes (multiple problems)  :: 2 of 26
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:33:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3737410
            Orig. end                         :: 3768396
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072679.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..30986
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="8"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..30986
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..30986
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:20986]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..20986
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     misc_feature    complement(143..154)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.67"
                     /tool="antismash"
     gene            complement(191..1120)
                     /gene="metA"
                     /locus_tag="J8Z22_RS17255"
                     /old_locus_tag="J8Z22_17240"
     CDS             complement(191..1120)
                     /EC_number="2.3.1.46"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /gene="metA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012196848.1"
                     /locus_tag="J8Z22_RS17255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17240"
                     /product="homoserine O-succinyltransferase"
                     /protein_id="WP_252007218.1"
                     /transl_table=11
                     /translation="MPVRIPSRLPASEILRSENIFVMSDERAESQDIRPLKLLILNLMP
                     NKIETETQLLRLLGNSPLQVDVELLRIHRKPSKHTSIDHMDDFYRDFDEVRDNNYDGLI
                     ITGAPLGNIEFEQVSYWNEICEIIQWSQQRATSVLFLCWAAHAALYHLYGIKRYLRDDK
                     ISGVFRHRRVHSHVPLLRGFDDEFWVPHSRYAQVSLDRLKAHDQLQVLAESDEAGAYLV
                     VSEDNRNLFVTGHPEYTRTTLQDEYRRDRAAGGSPQVPKNYYPKDDPTQPPHARWHAHG
                     ALLISNWLNYCVYQQTPYDLNSLHQKTE"
     gene            1286..2011
                     /locus_tag="J8Z22_RS17260"
                     /old_locus_tag="J8Z22_17245"
     CDS             1286..2011
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013344527.1"
                     /locus_tag="J8Z22_RS17260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17245"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_028112029.1"
                     /transl_table=11
                     /translation="MSQLSAIIVGANAGLSQMLAHKLASEGVRLGLLAADLDALAPTLD
                     KLPDNTLAREINIFDADASRAALQSLWQQFDGVQLVIINTAASHQELDLPWAADRQVLE
                     VNVTGFTALANAAFAEFREQKYGQLAAITSIAGERGGASSAFHASKAFQQNYLQGLRLH
                     AQRLKLPITISDLRLGFMEKMQARGSKAWGSNLNTMATQILKDLKRARHTSYVTRRWRL
                     IAWLGRWLPEFIYNKRKYK"
     gene            complement(2071..2700)
                     /gene="ompW"
                     /locus_tag="J8Z22_RS17265"
                     /old_locus_tag="J8Z22_17250"
     CDS             complement(2071..2700)
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="ompW"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011623353.1"
                     /locus_tag="J8Z22_RS17265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17250"
                     /product="outer membrane protein OmpW"
                     /protein_id="WP_028112030.1"
                     /transl_table=11
                     /translation="MMKQTLVAALVLASLSAPAFAAREAGDFIVRAGWAQVNPDESSPD
                     VAGQGSFTVDEDNQLGLNFTYMLTDAWAIEVLAASPFKHDVGLEKVGKIAEVTHLPPTV
                     MAQYYFGSGNLRPYVGAGINYTYFWDEEFTNDLGGALTDLEASDSWGLAGQVGIDYEIN
                     SNWLVNASIWYIDIQTDVEFKLAGDDVKIKTDIDPWVYMVSVGYKF"
     gene            complement(2945..3343)
                     /locus_tag="J8Z22_RS17270"
                     /old_locus_tag="J8Z22_17255"
     CDS             complement(2945..3343)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021158.5"
                     /locus_tag="J8Z22_RS17270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17255"
                     /product="YbaY family lipoprotein"
                     /protein_id="WP_028112031.1"
                     /transl_table=11
                     /translation="MYKSLLTAVLLLVLTGCVTVSGPELEHQDMVSVAGLAGANGVTTL
                     PQEAVITVAIIDAKVPGSILAQKRFSVAKLPALFKFQLPKESIDDDADYVVVAMLKIKD
                     KLVLQTYQRYPVITNGEEVATVTMEVLR"
     gene            complement(3421..4782)
                     /locus_tag="J8Z22_RS17275"
                     /old_locus_tag="J8Z22_17260"
     CDS             complement(3421..4782)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1153: Amino acid carrier protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013344517.1"
                     /locus_tag="J8Z22_RS17275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17260"
                     /product="sodium:alanine symporter family protein"
                     /protein_id="WP_252007220.1"
                     /transl_table=11
                     /translation="MNTIEHALSTLSSWVWGPPLLILLVGTGCYFTYQLRLMQVRKLPL
                     AISLMLRPNQAQGDISSFSALCTALAATIGTGNIVGVATAIKLGGPGALFWMWMAGFAG
                     MATKYAECMLAVKYRRQDERGQQVGGPMYYILHGTGKAWLAKLFAFFTLGVAFFGIGTF
                     PQVNAIVDGARIAFSIPDWFSMAALAILVALVTLGGVKRIAKVATALVPSMAVFYVIAC
                     VMLLGLNWAAVPAAAALVVEAAFTPQAAGGGFAGATVMMAIQFGIARGVFSNESGLGSA
                     PMAAAAARTNSPVEQGLVSMTGTFFDTIVICTLTGLTLIVTGAWQGELAGAAMTSSAFT
                     SGLSATVGQQVITLALLFFAFTTILGWNYYGERAVLFLWGERARLPYRWCFVALVAVGG
                     LLQLDMIWLLADVVNGLMAVPNLIALLLLRKEVVADTLAYFAARQPVTGVQQPG"
     misc_feature    4880..4890
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     regulatory      complement(4882..4990)
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    5147..5162
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            complement(5166..6035)
                     /locus_tag="J8Z22_RS17280"
                     /old_locus_tag="J8Z22_17265"
     CDS             complement(5166..6035)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013344516.1"
                     /locus_tag="J8Z22_RS17280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17265"
                     /product="acyl-CoA thioesterase domain-containing protein"
                     /protein_id="WP_028112033.1"
                     /transl_table=11
                     /translation="MSNSLDTLLEIMTLEQLEQGLFRGQSQDLGFGHLFGGQVLGQALA
                     AATQTVADDRQVHSFHSYFLRAGDLQRPVIYEVENMRDGGSISTRRVSAIQHGRPIFHL
                     TGSFHHSEPGFEHQAAMPDVAGPDGLANQFQLAEAMRGKVPDKLLDIYLNNTAIEIRLV
                     DPINPLKPEPREPVRYVWMKANGPLPSNQSLQQHLLAYASDLNFLVTAAQPHGVSYLTP
                     GLKMATIDHSMWFHRPVAFDQWLLYAVDSPNAMNSRGLVRGQIFNQQGQLVASSAQEGL
                     LRQMHRKS"
     gene            complement(6122..7009)
                     /locus_tag="J8Z22_RS17285"
                     /old_locus_tag="J8Z22_17270"
     CDS             complement(6122..7009)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (9-137). E-value: 4.9e-10. Score:
                     31.5. Matches aSDomain:
                     nrpspksdomains_J8Z22_RS17285_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.5"
                     /locus_tag="J8Z22_RS17285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17270"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_051252434.1"
                     /transl_table=11
                     /translation="MNSIRFDDQVVILSGAGRGLGRAFAIALAERGAKLVLVDNGCDAD
                     GSGVDASYVEEVAALVDSLDGEALPICADVTDYQAMEAVVEAAVKRFGRVNAVVANAGI
                     LIQQTIQCQLDEYRRMMEVNHFGTVNLIHAATDELIKSQGAIVVGCGFSGLYGDRELGG
                     FGASMMANRGFMLSLSHLTTEYGIRCNALCASAATRMVSSFYDAEQLKYLQSSAVVPGL
                     LYLLSPQAPNGVTLTAAAGHFTLAKTVETHGIKLRPENQRPEELCLAWDELKSESVVNP
                     YSSFRDRIRNLFSW"
     aSDomain        complement(6599..6982)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J8Z22_RS17285_PKS_KR.1"
                     /evalue="4.90E-10"
                     /label="J8Z22_RS17285_PKS_KR.1"
                     /locus_tag="J8Z22_RS17285"
                     /protein_end="137"
                     /protein_start="9"
                     /score="31.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVILSGAGRGLGRAFAIALAERGAKLVLVDNGCDADGSGVDASYV
                     EEVAALVDSLDGEALPICADVTDYQAMEAVVEAAVKRFGRVNAVVANAGILIQQTIQCQ
                     LDEYRRMMEVNHFGTVNLIHAATD"
     CDS_motif       complement(6896..6979)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J8Z22_RS17285_0001"
                     /evalue="9.10E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="J8Z22_RS17285"
                     /protein_end="38"
                     /protein_start="10"
                     /score="18.3"
                     /tool="antismash"
                     /translation="VILSGAGRGLGRAFAIALAERGAKLVLV"
     misc_feature    7082..7096
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.18"
                     /tool="antismash"
     gene            7243..8124
                     /locus_tag="J8Z22_RS17290"
                     /old_locus_tag="J8Z22_17275"
     CDS             7243..8124
                     /EC_number="2.5.1.74"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0046428 - 1,4-dihydroxy-2-naphthoate
                     octaprenyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011496111.1"
                     /locus_tag="J8Z22_RS17290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17275"
                     /product="1,4-dihydroxy-2-naphthoate polyprenyltransferase"
                     /protein_id="WP_035415435.1"
                     /sec_met_domain="ubiA (E-value: 1e-15, bitscore: 55.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLQYWILAIRPRTLPAAIGPLLVGNVLAVYHQDFSWLVAIASMA
                     CAVLLQIGVNLANDYFDFKSGVDTDERLGPTRVTQQGLLSATSVRNGMILSLTLATLIG
                     QYLIFVGGWPIAGLALFALAGALCYSGGPYPLASHGLGEIAAYIYFGLVAVVGSYFIQT
                     GTTDSSAWLLASAVGLLNAAIMLVNNTRDRSTDIKAGKRTLAVRLGLERSQLLYQMLIA
                     SPYLMVTLGWLMGLLPGATVAACAISIPMAKALATEFAHTQGAALNPLLGRTAKLTMFF
                     SGLASGGLLMAL"
     misc_feature    complement(7257..7270)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.57"
                     /tool="antismash"
     misc_feature    complement(8184..8199)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     misc_feature    complement(8216..8232)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 25.04"
                     /tool="antismash"
     gene            8257..9945
                     /locus_tag="J8Z22_RS17295"
                     /old_locus_tag="J8Z22_17280"
     CDS             8257..9945
                     /EC_number="1.1.1.38"
                     /GO_function="GO:0004470 - malic enzyme activity [Evidence
                     IEA]"
                     /GO_function="GO:0004471 - malate dehydrogenase
                     (decarboxylating) (NAD+) activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011636309.1"
                     /locus_tag="J8Z22_RS17295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17280"
                     /product="NAD-dependent malic enzyme"
                     /protein_id="WP_028112035.1"
                     /transl_table=11
                     /translation="MEDIKRPLYIPYAGPVLLETSLLNKGSAFSEEERVAFNLAGLLPE
                     AIENIEEQAERAYLQFQNFSNDMDKHIYLRNIQDTNETLFYRLVNNHITEMMPIIYTPT
                     VGEACEQFSNIYRRARGLMVSYPNRHRIDDILNNATRHNVRVIVITDGERILGLGDQGI
                     GGMGIPIGKLSLYTSCGGISPAYTLPIVLDVGTDNPQRLNDHMYMGWRNKRISGDEYNE
                     FVDDVLSAVQRRWPNALVQFEDFAQKNAMPLLERYKDRLCCFNDDIQGTAAVTVGSLLA
                     ACKAAGTQLKQQTIAFLGAGSAGCGIAEAIIAQMVAEGLEDHQAREKVHMVDRWGLLQE
                     GMQNLLPFQQKLTQCLDKTQSWSGDNGAVSLLEVMEHAKPTVLIGVSGAPGLFTEEVIK
                     TMHKHCPRPIVFPLSNPTSRVEAIPEDILRWTQGQALVATGSPFNPVELDGEVFPIAQC
                     NNSYIFPGIGLGVLACNADRVTDGMLMASSRALAECSPLAIEGEGALLPPLEQIQEVSK
                     QIAFAVARAAMTDGVAKMIKNVDLKDAIERQFWQPEYRDYKRTSF"
     gene            complement(10001..11926)
                     /locus_tag="J8Z22_RS17300"
                     /old_locus_tag="J8Z22_17285"
     CDS             complement(10001..11926)
                     /NRPS_PKS="Domain: AMP-binding (66-503). E-value: 2.6e-88.
                     Score: 288.3. Matches aSDomain:
                     nrpspksdomains_J8Z22_RS17300_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012277976.1"
                     /locus_tag="J8Z22_RS17300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17285"
                     /product="propionyl-CoA synthetase"
                     /protein_id="WP_252007222.1"
                     /sec_met_domain="AMP-binding (E-value: 5.7e-94, bitscore:
                     313.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLNKVKQMQQQAWQNPQAFWRHAATQIEWMQPVDQVLDDRDAPF
                     YRWFPGASLNTCYNAVDRHVEAGHGQQVAIQYVSPVTGTEEAISYQQLQQRVATLAGAM
                     ANLGVGKGDRVVIYMPMIPETAYAMLACARLGAVHSVVFGGFAPPELASRIDDAKPKLV
                     LSASCGIEPSGVIPYKPLLDKALDLCEHRVEYAVVFQRPQCPADLERQGDRDWQQLVAQ
                     AQPVPCVEVAASDPLYILYTSGTTGRPKGVVRDNGGHAVALAWSMKQIYNIDAGDVFWA
                     ASDVGWVVGHSYIVYGPLLARATTLLYEGKPVGTPDAGAFWRIIEQYRVKTFFTAPTAI
                     RAIKRVDATASLLQGVDISSLQALFLAGERCDPDTLTWAADMLQVPVVDHWWQTETGWP
                     ICANPLGMAPLPIKPGSPALAVPGYQVEVLDELGQPVAAGQSGAVTIKLPLPPGTLMTL
                     WNNDDRYRDGYLSRYPGYYLTGDAGYMDEDGYLYVMGRVDDIINVAGHRLSTGRFEEVL
                     AQHGAVAEAAVIGVKDTLKGQLPLGLVVLKQGMDTDLERIKTELVALVRAEVGAVAAFK
                     LVAVVEKLPKTRSGKILRGTMRKLANGETVVPPATIEDPDSLNVIGQALAQMGLTTAHQ
                     PVLDLS"
     aSDomain        complement(10418..11728)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J8Z22_RS17300_AMP-binding.1"
                     /evalue="2.60E-88"
                     /label="J8Z22_RS17300_AMP-binding.1"
                     /locus_tag="J8Z22_RS17300"
                     /protein_end="503"
                     /protein_start="66"
                     /score="288.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AGHGQQVAIQYVSPVTGTEEAISYQQLQQRVATLAGAMANLGVGK
                     GDRVVIYMPMIPETAYAMLACARLGAVHSVVFGGFAPPELASRIDDAKPKLVLSASCGI
                     EPSGVIPYKPLLDKALDLCEHRVEYAVVFQRPQCPADLERQGDRDWQQLVAQAQPVPCV
                     EVAASDPLYILYTSGTTGRPKGVVRDNGGHAVALAWSMKQIYNIDAGDVFWAASDVGWV
                     VGHSYIVYGPLLARATTLLYEGKPVGTPDAGAFWRIIEQYRVKTFFTAPTAIRAIKRVD
                     ATASLLQGVDISSLQALFLAGERCDPDTLTWAADMLQVPVVDHWWQTETGWPICANPLG
                     MAPLPIKPGSPALAVPGYQVEVLDELGQPVAAGQSGAVTIKLPLPPGTLMTLWNNDDRY
                     RDGYLSRYPGYYLTGDAGYMDEDGYLYVMGRVDDIINV"
     CDS_motif       complement(11168..11215)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J8Z22_RS17300_0002"
                     /evalue="6.70E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="J8Z22_RS17300"
                     /protein_end="253"
                     /protein_start="237"
                     /score="24.8"
                     /tool="antismash"
                     /translation="YILYTSGTTGRPKGVV"
     CDS_motif       complement(11669..11704)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J8Z22_RS17300_0001"
                     /evalue="7.60E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="J8Z22_RS17300"
                     /protein_end="86"
                     /protein_start="74"
                     /score="-2.6"
                     /tool="antismash"
                     /translation="IQYVSPVTGTEE"
     gene            12094..12495
                     /locus_tag="J8Z22_RS17305"
                     /old_locus_tag="J8Z22_17290"
     CDS             12094..12495
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011623082.1"
                     /locus_tag="J8Z22_RS17305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17290"
                     /product="MerR family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_028112037.1"
                     /transl_table=11
                     /translation="MTETTDVTYSISELAREFDITTRSIRFYEDQGLISPRRRGQTRIY
                     SLQDKVRLKLILRGKRLGFSLAETGRLFDLYDADKSSGTQLHTMLELIETKKADLQQQM
                     DDIKVVMMELSSAEQQCKQALQELTAELQ"
     gene            12566..13735
                     /locus_tag="J8Z22_RS17310"
                     /old_locus_tag="J8Z22_17295"
     CDS             12566..13735
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012587284.1"
                     /locus_tag="J8Z22_RS17310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17295"
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="WP_252007224.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 6.6e-40, bitscore:
                     134.3, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4.2e-26, bitscore:
                     89.0, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4e-44, bitscore:
                     148.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLYQSSFNYGLGETLEMLRDSVRDFAQAEIAPLAADIDSNNSFP
                     NELWSKMGDMGLLGITVAEEYGGVNMGYLAHAIAMEEISRASASVGLSYGAHSNLCVNQ
                     IHRNGSHEQKAKYLPKLVSGEHIGALAMSEPNAGSDVVSMKLSARLDGDHYILNGNKMW
                     ITNGPDADTYVIYAKTDTSAGAKGMTAFIVERGFAGFSQAQKLDKLGMRGSNTCELVFQ
                     DTPVPVENVLGGVGNGAKVLMSGLDYERVVLAAGPLGIMAACLDQVVPYIHQREQFGQA
                     IGQFQLVQGKVADMYTRSNAARAYVYSVAQACDRGETTRKDAAGAILYSAELATQLALD
                     AIQLLGGNGYINEYATGRLLRDAKLYEIGAGTSEIRRFLIGRELFTETA"
     gene            13783..15390
                     /locus_tag="J8Z22_RS17315"
                     /old_locus_tag="J8Z22_17300"
     CDS             13783..15390
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013050564.1"
                     /locus_tag="J8Z22_RS17315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17300"
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_028112039.1"
                     /transl_table=11
                     /translation="MTILRSSINRQEPGFMARRDAMADLVADLTATLDAIVPGGNDRAR
                     NKHLAQGKLLPRQRVELLLDPGAPFLELSQLAAHECYDDKVPAAGVIAGIGRVSGIECM
                     IVANDATVKGGTYYPLTVKKHLRAQEIAEKCHLPCIYLVESGGAFLPRQDEVFPDKDHF
                     GRIFFNQANMSAKGIPQIAVVLGLCTAGGAYMPAMADESIIVKEQGTIFLGGPPLVKAA
                     TGEEVSAEELGGGAVHTQISGVADHLADNDEHALQLARQAVARLNHHRAQPLADTDVRP
                     PRYPADDLYGIVGSNLKQPFEVREVIARLVDDSDFDEFKAGYGATLVCGFARIYGQPVG
                     ILANNGILFSESALKGAHFIELCCQRNIPLLFLQNITGFMVGKKYEHEGIAKHGAKLVT
                     AVSCARVPKFTVVIGGSYGAGNYGMCGRAYDPTMMWMWPNSRISVMGGEQAANVLAQVK
                     TDALARKGDSWSDDEQQAFKQPIVEQYERQGHPYYASARLWDDGIIDPAQTRDVVGLAL
                     TAAMNAPTEATRFGVFRM"
     gene            15401..16183
                     /locus_tag="J8Z22_RS17320"
                     /old_locus_tag="J8Z22_17305"
     CDS             15401..16183
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (9-223). E-value: 2.3e-42. Score:
                     136.9. Matches aSDomain:
                     nrpspksdomains_J8Z22_RS17320_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012141803.1"
                     /locus_tag="J8Z22_RS17320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17305"
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="WP_028112040.1"
                     /transl_table=11
                     /translation="MTFQFITLTQSDGVARLTLNRPDKHNAFGDAMIAEINQALTGLTR
                     QPPTLLVLAANGKHFSAGADLAWMKSQAAMDQASNLSDARELARLMHTLDRFPAPTLAL
                     VDGAAFGGALGLIACCDIALASPRARFCLSEVKLGLIPAVISPFVARAIGQRQSRRYML
                     SAETFDANTAHQIGLVHEVCDDLHSSSERLITTLTGNGPKAMQACKSLLHTIEQHPFDD
                     ALLALTADAIAHIRVSPEGQEGLQAFFDKRPPLWQGES"
     aSDomain        15428..16069
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J8Z22_RS17320_ECH.1"
                     /evalue="2.30E-42"
                     /label="J8Z22_RS17320_ECH.1"
                     /locus_tag="J8Z22_RS17320"
                     /protein_end="223"
                     /protein_start="9"
                     /score="136.9"
                     /tool="antismash"
                     /translation="QSDGVARLTLNRPDKHNAFGDAMIAEINQALTGLTRQPPTLLVLA
                     ANGKHFSAGADLAWMKSQAAMDQASNLSDARELARLMHTLDRFPAPTLALVDGAAFGGA
                     LGLIACCDIALASPRARFCLSEVKLGLIPAVISPFVARAIGQRQSRRYMLSAETFDANT
                     AHQIGLVHEVCDDLHSSSERLITTLTGNGPKAMQACKSLLHTIEQHPFDDA"
     gene            16183..18138
                     /locus_tag="J8Z22_RS17325"
                     /old_locus_tag="J8Z22_17310"
     CDS             16183..18138
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011866370.1"
                     /locus_tag="J8Z22_RS17325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17310"
                     /product="acetyl/propionyl/methylcrotonyl-CoA carboxylase
                     subunit alpha"
                     /protein_id="WP_252007226.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 4.8e-06, bitscore:
                     24.7, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 2.3e-08, bitscore:
                     31.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.2e-11,
                     bitscore: 42.4, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTKVLIANRGEIACRIIRTCQALGIRTVAVYSDADRNAQHVNMA
                     DEAFLLGPAAATESYLLGDKIVALASLAGVDGIHPGYGFLSENPEFARACADAGIAFIG
                     PNTEAIEQMGSKSAAKVIMERAGVPMLPGYHGDDQSDQRLTEEATKIGYPLLVKAAFGG
                     GGKGMRIVEHGDQLAAALATARREAQSAFGNDMLLLERFLAAPRHVEVQVFADAHGHCI
                     YLSDRDCSIQRRHQKVVEEAPAPGLSDTLRQQMGEAAVKAAKAIDYLGAGTVEFLLDDQ
                     GRFYFMEMNTRLQVEHPVTEMVTGQDLVHWQLLVASGQPLPLTQQQVEIRGHSLEVRLY
                     AEDPQREFLPATGTLTRFEVPASLRLDSGVVEGDEISPHYDPMIAKLITFGDTRTQAIQ
                     QMSRGLQQTQLAGVTSNLAFLGRIINHPQFQAADLDTRFIDTHYAQLTGADDLRHVAAI
                     AAALVISQPGCQRSPWHSVAGFRLNQSPVMHHHLEDDHGERYPLLVKGHWPALTVQLNE
                     VEYQAVIGIDDDQLSLELDGHLCHWPFQRCGESVTLFLPQGPLRFDAVSHQGGDGDDSG
                     EDALKAPMNGTVVTLLCELEQTVEAGQPLLVMEAMKMEYTITAPYAGQVLALPYGPGQQ
                     VNDGTALVTLEALEES"
     gene            18135..19040
                     /locus_tag="J8Z22_RS17330"
                     /old_locus_tag="J8Z22_17315"
     CDS             18135..19040
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007649005.1"
                     /locus_tag="J8Z22_RS17330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17315"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_028112042.1"
                     /sec_met_domain="HMGL-like (E-value: 7e-54, bitscore:
                     181.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHATIVEVGPRDGLQNEAAVTLAQRIALVDALSGTGLSQIEAGS
                     FVSPKWVPQMADADQLFARIQRRPGVRYSALTPNIKGFDAAQQAKVDGVAVFGAASESF
                     SQRNINCSISESLQRFEPVFAAARRAGLPVRGYVSCVLGCPYEGDIDVAKVADVAESLY
                     RMGCYEISLGDTIGVGTPAKAKAMLAAVTERIPVSALALHFHDTYGQALANVLACLDLG
                     VTTFDSAVAGLGGCPYAKGASGNLATEDLLYMLHGLGMDTGVNLDAVIAAGTTICRQLN
                     KPPSSKVAQAWLANHKEQPA"
     gene            19037..20986
                     /locus_tag="J8Z22_RS17335"
                     /old_locus_tag="J8Z22_17320"
     CDS             19037..20986
                     /EC_number="6.2.1.16"
                     /GO_function="GO:0030729 - acetoacetate-CoA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (95-523). E-value: 6.3e-56.
                     Score: 181.6. Matches aSDomain:
                     nrpspksdomains_J8Z22_RS17335_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011234130.1"
                     /locus_tag="J8Z22_RS17335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17320"
                     /product="acetoacetate--CoA ligase"
                     /protein_id="WP_252007228.1"
                     /sec_met_domain="AMP-binding (E-value: 5.6e-56, bitscore:
                     187.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHSPIWQPSQSRIDASQMEAFRHFVNDKLALTLSDYQQLHRWS
                     TDHPDQFWQAIWQFSEVIGTPGQRLLLDGDKMPGARFFPDARLNFAENLLRYQDDRIAL
                     VFRDEAANRVALSYNELYHEVARLAHHLRHLGVVAGDRVAAFMPNRIETVVTMLAAASL
                     GATFSSCSPDFGFNGVLDRFGQIQPKVLVAANGYRYNGKVIDCSDKIAQIADAIGSLQQ
                     VIVVPAFDAVAQVQHPLAIGWHQALDNPARSVSFTPLPFDHPLYVLYSSGTTGQPKCIV
                     HGAGGTLLQHLKELRLHTDIQRRDVLFYFTTCGWMMWNWLISGLATGATLVLYDGSPFA
                     PGPEVLWQLAEQEEVSVFGTSAKYIAALEKAGYRPAEHHRLTQLKGLLSTGSPLAHEGF
                     DFVYRHIHPDLCLSSISGGTDIVSCFALGNPIKPVYRGQLQSPGLGMKVEVYNEQGQPL
                     QQQKGELVCTTPFVSMPIGFWGDDDGSNYHHAYFDRFDNVWAHGDYAETTAEGGLIIHG
                     RSDAVLNPGGVRIGTAEIYRQVEKVDQVQESLAIGQQWQDDVRVVLFVVLKPGTRLTDA
                     LQQQIRTTIRANTTPRHVPAKIIQVQDLPKTLSGKLVELAVRKVVHGQAVTNTDALANP
                     ESLQQFKHLPDLQC"
     aSDomain        19322..20605
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J8Z22_RS17335_AMP-binding.1"
                     /evalue="6.30E-56"
                     /label="J8Z22_RS17335_AMP-binding.1"
                     /locus_tag="J8Z22_RS17335"
                     /protein_end="523"
                     /protein_start="95"
                     /score="181.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RYQDDRIALVFRDEAANRVALSYNELYHEVARLAHHLRHLGVVAG
                     DRVAAFMPNRIETVVTMLAAASLGATFSSCSPDFGFNGVLDRFGQIQPKVLVAANGYRY
                     NGKVIDCSDKIAQIADAIGSLQQVIVVPAFDAVAQVQHPLAIGWHQALDNPARSVSFTP
                     LPFDHPLYVLYSSGTTGQPKCIVHGAGGTLLQHLKELRLHTDIQRRDVLFYFTTCGWMM
                     WNWLISGLATGATLVLYDGSPFAPGPEVLWQLAEQEEVSVFGTSAKYIAALEKAGYRPA
                     EHHRLTQLKGLLSTGSPLAHEGFDFVYRHIHPDLCLSSISGGTDIVSCFALGNPIKPVY
                     RGQLQSPGLGMKVEVYNEQGQPLQQQKGELVCTTPFVSMPIGFWGDDDGSNYHHAYFDR
                     FDNVWAHGDYAETTAEGGLIIHGRSDAVL"
     CDS_motif       19832..19879
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J8Z22_RS17335_0001"
                     /evalue="9.10E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="J8Z22_RS17335"
                     /protein_end="281"
                     /protein_start="265"
                     /score="18.4"
                     /tool="antismash"
                     /translation="YVLYSSGTTGQPKCIV"
     misc_feature    21121..21134
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.12"
                     /tool="antismash"
     misc_feature    complement(21122..21135)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.78"
                     /tool="antismash"
     misc_feature    21275..21288
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.38"
                     /tool="antismash"
     gene            21332..>21472
                     /locus_tag="J8Z22_RS22245"
                     /pseudo=""
     CDS             21332..>21472
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012354.5"
                     /locus_tag="J8Z22_RS22245"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRDFDSIDIRLLIVFRAVVFTGSLSKAARKLSVTPSAVSQSLSKL
                     SK"
     gene            21533..22249
                     /locus_tag="J8Z22_RS17340"
                     /old_locus_tag="J8Z22_17325"
     CDS             21533..22249
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1125: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.5"
                     /locus_tag="J8Z22_RS17340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17325"
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_245595555.1"
                     /transl_table=11
                     /translation="MELYGYVNSALDLLQDGVESLSDFDPANSKRRFRISANHILDLII
                     LHPLARHIESFNSQLKVSVNNLVEEESKIIDSLQIDNNDLCLVAMKIDMKSIIQEKVLD
                     EEMVVLGCKSNPLTKEVIDMDTFLAQRHCRYAVGQIGYKMGNAMNMGYVDEREVFLDTN
                     NPFNAMMMTQGTDTLVTISRWLWEKYASQFELAEIKTSFDIPTVPLYLTYLKKMEDSKA
                     NRWLRDQVKQTLASLR"
     gene            complement(22470..23048)
                     /locus_tag="J8Z22_RS17345"
                     /old_locus_tag="J8Z22_17330"
     CDS             complement(22470..23048)
                     /EC_number="2.7.1.21"
                     /GO_function="GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014950261.1"
                     /locus_tag="J8Z22_RS17345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17330"
                     /product="thymidine kinase"
                     /protein_id="WP_028112045.1"
                     /transl_table=11
                     /translation="MAQLYFYYSAMNAGKSTSLLQSAYNYRERGMQVLVMTAGLDDRYG
                     QGKVTSRIGLSSDALIYRKEDDLIQMVLRENDAQAVNCLLVDECQFLTKSQVRQLTYLV
                     DKMDIPVLCYGLRTDFQGELFEGAQYLLAWADKLVELKTICHCGRKANMVVRLDETGNP
                     VRNGDQVQIGGNDSYVSMCRTHYRELAWD"
     misc_feature    complement(23070..23088)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.35"
                     /tool="antismash"
     gene            complement(23183..24742)
                     /locus_tag="J8Z22_RS17350"
                     /old_locus_tag="J8Z22_17335"
     CDS             complement(23183..24742)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011866379.1"
                     /locus_tag="J8Z22_RS17350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17335"
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="WP_252007230.1"
                     /transl_table=11
                     /translation="MALISYADSALSLLPPVVAIGMAIASRKVLLSLGLGIAIGILMLV
                     DFSVVDGASELGSRAVSLVWDDGALNSWNLYTLGFLVLLGVMTALISVSGATRAFADWA
                     RHRIRCGRDAKLMTMALGVVIFIDDYFNTLVVGSVARPVTDHYQVSREKLAYCIDSTSA
                     PICVISPISSWGAYIIALIGGLLTTHGMTDIGYLSAFMQMVPMNFYAIFAFALLLAVVY
                     FGLDFGAMADAEQRAQRGQLWDEAKGVPAGEELDLPEANNGRVAGLVAPIGFLIAITVS
                     LMLFSGNQVLAADDKAFSLIGAFENTDVAWSLFYSGLAGVGFTLLFGLRQGVPAAYMSK
                     AVISGVKSMLPAIYILLFAWTIAGVISDMKTGEFMATLAQGNLPAWGLPALLFLLSGFA
                     AFATGTSWGTFAIMLPIAANMAEAVDLALMLPMLSSVLAGAVFGDHCSPISDTTILSST
                     GAGCHHIDHVTTQLPYAVLTALISLAGYLVLGMTGSVMAGFATATLGLVLVILLLKRLC
                     RR"
     regulatory      complement(24829..25027)
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes and
                     Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational analysis
                     using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(25104..25119)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            complement(25121..26047)
                     /locus_tag="J8Z22_RS17355"
                     /old_locus_tag="J8Z22_17340"
     CDS             complement(25121..26047)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011574950.1"
                     /locus_tag="J8Z22_RS17355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17340"
                     /product="FAD-binding protein"
                     /protein_id="WP_252007232.1"
                     /transl_table=11
                     /translation="MAILIIAELDKQGLGAECAKVVGAATQLGQEIHVLVAGSGVAEAA
                     NQAAQLAGVTKVLLADHDGYAHQLAEPVADLVLELAGGYSHILTAASAKGKDVLPRAAA
                     LLDVAQHSDVIAIESEDTFVRPIYAGNALATVQSLDAIKVLTIRTSAFDAVATQAAADI
                     ETVSSVKDSGLSQFVGEELVQSERPELGAARVVISGGRGLGSGENFALIEALADKLGGA
                     IGASRAAVDAGYVANDLQVGQTGKIVAPELYIAVGISGAIQHLAGMKESKVIVAINKDP
                     DAPIFQVADYGLEADLFDAVPKLTELL"
     gene            complement(26047..26796)
                     /locus_tag="J8Z22_RS17360"
                     /old_locus_tag="J8Z22_17345"
     CDS             complement(26047..26796)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003461132.1"
                     /locus_tag="J8Z22_RS17360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17345"
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="WP_252007234.1"
                     /transl_table=11
                     /translation="MKILVPIKRVVDPYVKVRVAADESAVELANLKMAINPFCEIAVEE
                     AVRLKEKGQADEIIAVSIGPKVAQEQLRTAMALGADRGILVEHDEELAPISIAKVLKAV
                     VDKEQPDLVLFGKQSIDGDNNQTAQMTAALAGMGQATFASSIEVEGDQVTVAREIDGGI
                     QTLSVKLPAVVSADLRLNEPRYASLPNIMKAKRKPLDTVTVADFELQLKSHQQVIKVTA
                     PAERSGGIMVGSVEELVEKLKNEAKVV"
     gene            27109..27501
                     /locus_tag="J8Z22_RS17365"
                     /old_locus_tag="J8Z22_17350"
     CDS             27109..27501
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0030527 - structural constituent of
                     chromatin [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011716472.1"
                     /locus_tag="J8Z22_RS17365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17350"
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_028112049.1"
                     /transl_table=11
                     /translation="MADFLEILTHGRRLKAQVKELELDELKDVIAKLQKIADEREAEAE
                     EEIAAQAERLAKIEAIRKQLAEDGISVDELNALESASPRRKRAPRPAKYKIVVDGETLT
                     WTGQGRTPKAIKEKLDQGHSLEEFLI"
     misc_feature    27116..27130
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    27544..27553
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.86"
                     /tool="antismash"
     gene            27643..30669
                     /locus_tag="J8Z22_RS17370"
                     /old_locus_tag="J8Z22_17355"
     CDS             27643..30669
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011073037.1"
                     /locus_tag="J8Z22_RS17370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_17355"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_252007236.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 5e-17, bitscore:
                     60.1, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLPTTHWRWRRLCQVLACAASLPAFASPTQPVSAIANADDHYLA
                     FTHATLIPTPGQRLENATLVIKDGKIVSISESNKVPDGAREIHSRGKTIYPGFIDPYTD
                     FGQQWQYSDYPDGGPHYNAEQAGAKVNNRAIHAEMNWADHFQFDHERAQDWHNNGFTSV
                     QTGKLDGLFQGMSATVSLIDLHSESSIYAIEGAHLMSFDKGSSEQEYPNSLMGSIALIR
                     QTLKDAQWYQQQSSKSIPQLSLNLNQTFTKLLQFNNQRIIFDPGQGNNASRALQLLQPF
                     HPSPVLVGNGLEFERLESLKQTRLILPLTLAAKPPLDAGLDISLKQLRHWERSPGNLAA
                     VAAANIPFAITQHGIDPLEFWNRITKAVEYGLPKSTALAALTTVAAEYAGVDDFLGQLQ
                     PGFQADLVIATGDLFAGAEIESLYLKGRPLPLNPQLGSRLSGQYQLSIDETDLTLVLSQ
                     DQGELSAQLESGERLILLDVSHSAAEQFSAVADLTELGLPGLTRLTLHRVRQGLFGNLT
                     QHDGQLLPLAASYLGPIATSTEPEPVTTPTYLSRLTRPNRAFGTDAPLQQERLHIRGAT
                     LWTAADDGIIADADLLIDNGVIRAIGENLTTPEGFDVLDAQGKHLTPGFIDEHSHIAIR
                     GGVNEASDSNTAEVRIGDVLDADDIHIYRSLAGGVTTAQLLHGSANVIGGQAQVIKLRW
                     GESDHDLKFQQAPASIKFALGENVKQSNWGDRYVSRFPQTRMGVEAYLEDQFEQARKLQ
                     RQQQAYQSLSRNQKRRQLAPRPNDRLEALIEILNGSRNIHVHSYVQSEILMLLRLSQRL
                     GFHVQTFTHILEGYKVADEMASYGTSASTFSDWWAYKFEVYDAIPHNACLLLQKGVNTS
                     INSDSADLIRKLNQEAAKSMMYCGMSAEQALKMITINPARQLKIDRYTGSLETGKQADL
                     VLWDQPPMSVYARVESTWVDGVRRFDRQRDRQLQRQAGAERQALIQKLLLDDSDDGEGE
                     SLTPDEVPLWHCDSLIHQH"
     misc_feature    30972..30986
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.77"
                     /tool="antismash"
ORIGIN
        1 ctgtccctga ggaaccacga cttcttcgtt gacgacggaa cgctctcgtc tcatgtgacc
       61 tacatcctgt agttaattat ccaatgtcta ctcgggtcac attttaccta ttgccaaggg
      121 atagcgccat ctgttagggg cggaaatctt tttccgcccc tagtttaaaa aaccatattt
      181 atcagtggtt ttattcggtt ttttgatgaa gtgaattcag atcgtagggg gtttgctgat
      241 agacacaata gttaagccag ttgctgatca acaaggcgcc atgggcatgc caacgggcgt
      301 ggggcggctg ggttggatca tccttggggt agtagttttt cggcacctga ggactgccac
      361 cggcggctct gtcgcgtcga tactcatcct gcaatgtggt gcgggtgtac tcgggatgac
      421 cggtgacaaa caggttgcgg ttgtcctcac tgacaaccag gtaggccccg gcctcatcgg
      481 attctgccaa cacctgcaac tggtcgtggg ccttaagccg gtccaggctg acctgggcgt
      541 aacgggagtg cggtacccag aattcgtcgt cgaaccccct cagcaacggc acatggctgt
      601 gcacccggcg atgacgaaag accccggaga tcttatcgtc ccgcaggtac cgtttaatgc
      661 catacaagtg atacagagcc gcatgagccg cccagcacaa aaacaacacc gaggtcgccc
      721 gctgttgcga ccactgaatg atttcacaga tctcattcca ataactgacc tgctcgaact
      781 cgatgttgcc cagcggcgcc ccggtgatga tcaggccatc gtagttgttg tcccgcacct
      841 catcgaaatc acgataaaaa tcgtccatgt ggtcaatgga ggtgtgcttg gaaggcttgc
      901 ggtgaatccg cagcaactcg acatccacct gtaacggcga gttacccaac aaccgcaaca
      961 actgagtttc cgtttcaatt ttattgggca tcaggttgag gatcagtagc ttaagaggcc
     1021 gaatgtcctg tgattcggcc cgctcatcgg acatgacaaa gatgttctcg ctgcgcaaaa
     1081 tttccgatgc gggcaaacga ctgggtattc tgactggcat ggcacctctc ctcacttgat
     1141 accctgttat accaagacat ctagacggct acaactccag acagccaaaa aatcgacatc
     1201 ctgccattga cgacccgggt tagccgcaga agccaggcgc aataactgct atcattccgc
     1261 tacttagaat gaaatgaagg tcgatatgag ccaactctcc gccattatcg tcggcgccaa
     1321 tgccggcctc agtcagatgc tggcccacaa gctggccagt gaaggggttc gcctgggtct
     1381 gctggccgcc gatctcgatg ccctggcccc gaccctggac aagctgccgg acaacacgtt
     1441 agccagagag attaacatct tcgacgccga cgccagccgc gcggcgctgc agagcctgtg
     1501 gcagcagttt gacggggttc agctggtgat catcaacacc gccgcctccc accaggagct
     1561 ggatctgccc tgggccgccg atcgacaggt actggaggtc aacgtcaccg gtttcaccgc
     1621 cctggccaac gccgcctttg ccgaatttcg cgagcagaaa tacggccaac tggccgccat
     1681 tacctccatc gccggcgagc gcggcggcgc cagcagtgcc ttccacgcca gtaaggcgtt
     1741 tcaacaaaac tacctgcagg gactgagact gcatgcccag cgactgaaac tgccgatcac
     1801 catcagcgac ctgcggctgg ggttcatgga aaagatgcag gctcggggca gcaaggcctg
     1861 gggctcaaac ctcaacacca tggccaccca gatcctcaaa gatctgaaac gagcccgcca
     1921 caccagctac gtcactcgcc gctggcgact gatcgcctgg ctgggtcgtt ggttgcctga
     1981 gttcatctac aacaagcgca aatacaagta atctcagggc caaaaaaaaa cgccggcata
     2041 cgccggcgtt gttcattgct cgaatggcaa tcagaacttg taacccacag acaccatgta
     2101 cacccaggga tcgatgtcgg ttttgatctt cacatcatcc ccggccagct tgaattccac
     2161 gtcggtctga atgtcgatgt accagatgga ggcattcacc agccagttgc tgttgatttc
     2221 ataatcgatg cccacctgac ccgccaggcc ccaggaatcc gatgcttcca aatcggtcag
     2281 ggcgccgccc agatcgttgg taaactcctc atcccagaaa taggtgtagt tgatacctgc
     2341 acccacataa ggacgcaagt tgccactgcc gaagtagtac tgggccatga ccgtcggcgg
     2401 cagatgggtg acttcggcaa ttttgccgac cttttccaga cccacatcgt gcttaaacgg
     2461 gctggctgcc agcacctcaa tggcccaggc gtcggtcagc atgtaggtaa agttcagacc
     2521 cagttggttg tcttcatcca cagtaaagga accttgaccg gccacatccg gggaggattc
     2581 atcgggattc acctgagccc aaccggcgcg gacaataaaa tcaccggctt cgcgggcggc
     2641 aaaggctggg gcagacaggg aagccagaac cagggcggct acgagggttt gtttcatcat
     2701 tattctcact ccatgaaaac tcggaaacca aattcatgcg gtttcccaac aagttgcgaa
     2761 ggaatgtaac aactaagagg tattgatttt ttgatctaaa acaggctttg atttgctaat
     2821 tgcgccctag cagctttttt tgatcgtgaa aagtgaccag gctcactttc gaacaacaaa
     2881 aaaggcaccg aaaggtgcct tggcgcaaaa tttgcgagtc tcaagaatcc gcctcgaacc
     2941 gcgatcagcg cagcacctcc atggtcaccg tagccacctc ttcgccattg gtgatcaccg
     3001 ggtagcgctg ataggtctgc agtaccaact tgtctttaat ttttaacatc gccaccacca
     3061 cgtagtcggc atcatcatcg atgctctcct taggcagctg aaatttgaac aacgccggca
     3121 gcttggcgac actgaaacgt ttttgcgcca ggatactccc cggtaccttg gcatcaataa
     3181 tggccacggt aatcaccgcc tcctgaggca gggtggtcac cccgttggca ccggccaggc
     3241 ctgccacact caccatatcc tgatgctcaa gctcaggtcc gctcacggta acgcagccgg
     3301 tcaacaccaa cagtaacacc gcagtcagca aggatttata catagaaaaa gctccagtta
     3361 tctggagcct ttataccaaa tctgcgctgc ggcgaacagt cgccgcagcg ctcagcccct
     3421 ctagccgggc tgttgaacac cggtcacagg ctgacgggcg gcgaagtaag ccagggtgtc
     3481 agccaccacc tctttacgca gcaacagcag cgcaatcagg ttcggtaccg ccatcaaacc
     3541 attcaccaca tccgccagca gccagatcat gtccagttgc agcaggccac ccacggccac
     3601 cagcgccaca aagcaccagc ggtaaggcaa gcgggcgcgt tcgccccaca gaaacagcac
     3661 ggcccgctcg ccgtagtagt tccagcccag gatggtggta aaagcgaaaa acaacagcgc
     3721 cagggtaatc acctgctggc ccactgtcgc cgacaggccg gaggtaaagg ccgacgacgt
     3781 catggccgct ccggccagct ccccctgcca ggcgccggtc acgatcagcg tcaggccggt
     3841 aagggtgcag atgacaatgg tatcgaaaaa cgttcccgtc atggacacca ggccctgctc
     3901 taccggagag ttggtacggg ccgctgccgc tgccatcggc gcgctgccga ggccggattc
     3961 attggaaaac accccgcggg caataccgaa ctgaatcgcc atcatcaccg tggcaccagc
     4021 gaagccgccg ccggccgcct gaggggtaaa ggccgcttcc accaccaatg ccgccgccgc
     4081 cggcaccgcc gcccagttca gtcccagcag catcacgcag gcgatcacgt aaaacaccgc
     4141 catggaaggc accagcgcag tagccacctt ggcaatgcgc ttaacgccgc caagggttac
     4201 cagggccacc aggatcgcca gcgccgccat ggagaaccag tcgggaatgc taaaggcgat
     4261 gcgggcgccg tcgacgatgg cattgacctg cggaaaggta ccgatgccga aaaacgccac
     4321 tccaagggta aagaaggcaa acagcttcgc caaccaggct ttgccggtac cgtggaggat
     4381 gtaatacatg ggtccgccca cctgctgtcc gcgctcatcc tgacgacggt acttcaccgc
     4441 cagcatgcat tcggcgtact tggtggccat gccggcaaac ccggccatcc acatccagaa
     4501 cagggcgccc gggcccccaa gcttgatggc ggtggccacg ccgacgatgt taccggtgcc
     4561 gatggtggcc gccagggcgg tgcacagggc cgagaaactg ctgatgtcgc cctgggcctg
     4621 attcggcctc agcatcagtg agatcgccag tggcagtttt cgcacctgca tcaggcgtaa
     4681 ctggtaggta aagtagcagc cggtgcccac cagcaggatc agcaacggcg gtccccatac
     4741 ccaactgctt agggtggaca gtgcgtgttc gattgtgttc attgattgtc ttcctcagtg
     4801 tgacatctta actacacaga ggagaaccat gccggacaga cagatccgag gatccgtcct
     4861 tttgaaagga aaaaaattga gcaatgtcac cctgtccttt tgcctgagcg tttgactcgc
     4921 caccgcccta gggggtgtcg agcttgcgcc ttcggcgtcc aagtcaatgg atctctccag
     4981 aggcccgtcc agtaacagtc catatcggca gaagccgacg cctgaaagat ttacttcttc
     5041 ggcggacgca gtgcgtcact ctcctattac cttcatccgg gtttccaccc gccaaggtgg
     5101 aactgcatac gttagcaaaa agcgcgccgt ttaggcgcgc ttttttggtg attattgtca
     5161 cataatcagg attttcggtg catctgtcta agcaaccctt cctgggccga agatgccacc
     5221 aactgcccct gctgattaaa aatctggccc cgaaccaggc cgcgggagtt catggcattg
     5281 ggggaatcga cggcgtacag caaccactgg tcgaacgcca ctggacggtg gaaccacatc
     5341 gagtgatcga tggtcgccat cttcaatccc ggcgtcaggt aagacacccc atggggttgt
     5401 gccgcggtca ccaggaagtt cagatccgac gcgtacgcca gcaggtgctg ctgcagggac
     5461 tggttgctcg gtaacgggcc attggccttc atccatacat agcgcaccgg ctcacggggt
     5521 tccggtttca acgggttgat ggggtccacc aatcgaatct cgatggcggt attgttgagg
     5581 tagatgtcta gtaacttgtc cggcaccttg ccccgcatcg cctcggccaa ctggaactgg
     5641 ttcgccagcc cgtcagggcc ggccacgtcc ggcatggcag cctgatgctc aaatccgggt
     5701 tcgctgtggt gaaaggagcc ggtcaggtga aaaatcggcc ggccgtgctg aatggcactg
     5761 acccggcgag tactgatgct gccgccatct cgcatgttct ccacttcata gatcaccggc
     5821 cgctgcagat caccggcacg cagaaaatag gagtgaaaag agtgcacctg acgatcgtcg
     5881 gccacggtct gagtcgccgc cgccagcgct tgacccagta cctgcccacc aaacaggtga
     5941 ccaaatccca gatcctgact ctgaccccga aacaggccct gctctagctg ctcgagagtc
     6001 atgatctcca gcagggtatc cagtgaattg gacattgatg cgtctctatt ttaccaatca
     6061 gccgttcatg gtacccaagg ctcacgcctt gggcaacggc gatgctgaga cgatgtcgcg
     6121 actaccagct gaacagattg cgaatccgat cccggaacga cgagtagggg ttcaccaccg
     6181 attcgctctt cagctcatcc caggccaggc acaactcctc cgggcgctgg ttctccggtc
     6241 ttagcttaat gccatgggtc tcaacggtct tggccagggt aaagtgaccg gcggccgccg
     6301 tcagcgttac cccattgggg gcttgcggag acagcagata cagcagtccg ggtaccacgg
     6361 cactgctttg caggtacttc agttgctcgg cgtcgtagaa agaagacacc atgcgggtgg
     6421 cggcggaagc gcataaggcg ttgcagcgaa tgccgtactc ggttgtcagg tgcgacaggg
     6481 acaacataaa gccgcgattg gccatcatac tggcgccaaa gcctcccagc tcgcggtcgc
     6541 cgtagaggcc tgagaagccg cagcccacca cgatggcccc ctggcttttg atcagctcgt
     6601 cggtggcagc atgaatcagg ttgacggtgc cgaagtgatt cacctccatc atccgccggt
     6661 actcgtcgag ctggcattga atcgtttgct gaatcagaat cccggcattg gccaccaccg
     6721 cattgacccg gccaaagcgc ttgaccgccg cctcgaccac cgcctccatg gcctggtagt
     6781 cggtgacgtc ggcgcagatc ggcaacgcct cgccatcgag gctgtccacc agtgccgcaa
     6841 cctcctccac gtagctggca tcgacgccac taccgtcggc gtcacagccg ttgtccacca
     6901 gcaccagctt ggcgccccgc tcggccaggg cgatggcaaa cgcccgtccc aggcctcgac
     6961 cggcgccaga gaggatcacc acctgatcat caaaacggat tgaattcata cactttccat
     7021 ccctgaattc cataccaacc caagtaactt ccccatcgat ttctattcgc caaagaaagc
     7081 actctccatt tgaaaacaat gagttaatcc taatttaatt gccagtatta actcggcttc
     7141 gttgtccgat tcttaacccg gatcacaacc gaataggatg aaaagtgaaa ctcctctctt
     7201 tcgggttaca ataaacgcgt cctaaccact tccagagaaa caatgaacct acaatattgg
     7261 attctggcca ttcggccccg taccctgccg gcagccatcg gccccctgct ggtgggcaat
     7321 gtcctggcgg tgtaccacca ggatttttcc tggctggtgg ccatcgcctc catggcctgc
     7381 gcggtgttgc tgcagattgg cgtcaacctg gccaatgact atttcgattt caaatccggt
     7441 gtcgataccg acgaacgcct ggggccaacc cgagtcaccc agcaagggtt gctgtcggcc
     7501 acctcggtgc gcaacggcat gatcctgtca ctgacgctgg ccaccctcat cggccagtac
     7561 ctgatctttg tcggcggctg gcctatcgcc ggattggcgc tgttcgccct ggccggcgcc
     7621 ctgtgctact ccggcggccc ctacccgctg gcctcccatg ggctgggaga aattgccgcc
     7681 tacatctatt ttggcctggt ggccgtggtg ggcagctatt tcattcagac cggcaccacc
     7741 gactccagtg cctggctgct ggccagtgcc gttggcctgc tcaatgccgc catcatgctg
     7801 gtgaacaaca ctcgggatcg cagcaccgac attaaagccg gcaaacgtac cctggctgtg
     7861 cgcctgggac tggagcggtc gcagttgctg taccagatgc tgattgccag cccctacctg
     7921 atggtgacgc tgggatggct gatgggactc ctgcccggcg ccaccgtggc cgcctgcgcc
     7981 atctccattc ccatggccaa ggccctggcg accgaattcg ctcataccca gggcgccgcc
     8041 ctcaacccgc tgttggggcg cacagccaaa ctgacgatgt ttttcagtgg cctggcatcc
     8101 ggtggcttgc tgatggcgct gtaagcctgc gtcactaaaa cacccaagcg ggcctcgagc
     8161 ccgctttttt attgccgagc ctcagtgatg agtgtcacac tcaggccagt tactgataca
     8221 ctagaggggt ctaaaaccac aaataaaaac atgccgatgg aagatattaa acgtcccctg
     8281 tacatcccct atgctggccc ggtgctgctc gaaacctccc tgctgaacaa aggctccgct
     8341 ttctccgaag aggaaagagt ggcattcaac ctggcaggcc tgttacctga agcgattgaa
     8401 aatattgaag aacaggcaga acgcgcctac cttcagtttc aaaatttcag taacgacatg
     8461 gataagcaca tctacctgcg caacatccag gacaccaacg aaaccctgtt ctatcgactg
     8521 gtgaacaacc acatcaccga gatgatgccg atcatctaca cccccacggt tggtgaggcc
     8581 tgtgaacagt tctccaacat ctaccgccgt gcccgcggcc tgatggtcag ttaccccaac
     8641 cgtcaccgca tcgatgacat cctcaacaac gccacccggc ataacgtgcg agtcatcgtg
     8701 atcaccgatg gtgagcggat cctgggtctg ggcgaccagg gcatcggtgg catgggcatt
     8761 cccatcggca aactgtcgct gtacacctcc tgcggcggca tcagcccggc ctacaccctg
     8821 cccatcgtgc tggatgtggg caccgacaac ccccagcgcc tcaacgacca catgtacatg
     8881 ggctggcgca acaagcgtat ctccggtgac gaatacaatg agtttgtcga tgacgtgctc
     8941 agtgccgtgc aacgccgctg gcccaatgcg ctggtgcagt ttgaagattt tgcccagaaa
     9001 aatgccatgc cactgctgga gcgctacaaa gaccggctgt gctgctttaa cgacgacatt
     9061 caaggcaccg cggcggtcac cgtcggctcg ctgctggccg cctgcaaagc cgccggcacc
     9121 caactcaaac agcagaccat cgcctttttg ggcgccggct ctgccggttg cggcatcgcc
     9181 gaggcaatca tcgcccagat ggtggccgaa ggcctggaag atcaccaggc tcgagagaag
     9241 gtgcacatgg tcgatcgctg gggtctgctg caggaaggga tgcaaaacct gctgccgttc
     9301 cagcagaaac tgacccaatg cctggacaag acccagtcct ggagtggtga caacggcgcc
     9361 gtgtcgctgc tggaggtgat ggaacacgcc aaacccacgg tgctgatcgg cgtcagcggg
     9421 gcaccgggcc tgttcaccga agaggtgatc aagaccatgc acaagcactg tccccgcccc
     9481 atcgtgtttc cgctgtccaa ccccaccagt cgggtggaag cgattccgga ggacatcctg
     9541 cgctggacgc aaggccaggc cctggtcgcc accggcagcc ccttcaaccc ggtagagctg
     9601 gacggggagg tcttccccat cgcccagtgc aataacagct acatcttccc gggtatcggc
     9661 ctgggcgtgc tggcctgcaa cgccgaccgg gtcaccgatg gcatgctgat ggcctccagc
     9721 cgggccctgg cggagtgttc gcctctggcc atcgaagggg aaggcgcgct gttgcccccc
     9781 ctggagcaga ttcaggaggt cagcaaacag atcgcctttg ccgtggcccg ggccgccatg
     9841 accgacggcg tcgccaagat gatcaagaac gtcgacctta aagacgccat cgagcggcag
     9901 ttctggcaac cggaataccg cgattacaag cgcaccagtt tctgatcagc gccaacacca
     9961 aggggctccg aagagcccct tgttttaggc catcgcccac tcaggacagg tccagcaccg
    10021 gctgatgggc ggtggtcagc cccatctgcg ccaacgcctg gccgatgaca ttgaggctgt
    10081 ccgggtcttc gatggtggcc ggtggcacca ccgtctcacc gttggccagc ttacgcatgg
    10141 tgccccgcag gatcttaccg gaacgggtct tgggcaactt ttccaccacc gccaccagtt
    10201 taaaggccgc caccgcccct acctcggccc gcaccagcgc caccagctcg gttttaatcc
    10261 gctccagatc ggtgtccatc ccctgcttca gcaccaccaa gcccagcggc aactgcccct
    10321 taagggtgtc cttgacgcca atgaccgccg cctcggcgac cgccccgtgc tgcgccaaca
    10381 cctcctcgaa tcgaccggta gaaagccggt gcccggccac gttgatgatg tcgtccaccc
    10441 tgcccatgac atacaggtag ccgtcctcat ccatatagcc ggcgtcgccc gtcaggtaat
    10501 aacccgggta acggctcaaa tagccatccc ggtaacgatc gtcgttgttc cacaaggtca
    10561 tcaaggtgcc cggcggcagt ggcagtttga tggtgaccgc gccactttgt cccgcggcca
    10621 ccggctgacc caactcatcc agcacctcca cctgatagcc gggcactgcc agtgccggcg
    10681 accccggttt gatcggcagc ggcgccatgc ccaaggggtt ggcacagatg ggccagccag
    10741 tctcggtttg ccaccagtga tccaccaccg gcacctgcag catgtccgcg gcccaggtca
    10801 gggtatccgg gtcgcaacgc tcaccggcca ggaacagcgc ctgcaggctg ctgatgtcca
    10861 ccccctgcag caaactggcg gtggcatcca cccgcttgat ggcccgaatg gccgtcggag
    10921 cggtaaagaa ggttttcacc cggtactgct cgatgatccg ccagaaggca ccggcgtccg
    10981 gcgtccccac cggcttacct tcgtacagca acgtggtcgc ccgggccaac agcggcccat
    11041 aaacgatgta ggagtggccc accacccaac ccacgtccga ggccgcccag aacacatcgc
    11101 cggcatcgat gttgtagatc tgtttcatcg accaggccag cgccaccgca tggccgccgt
    11161 tatcacggac cacccctttg ggccgccctg tggtgccaga ggtatagaga atgtagagcg
    11221 ggtcactggc cgccacctca acgcagggca ccggctgtgc ctgcgccacc agttgctgcc
    11281 agtcccggtc gccctggcgc tccagatccg ccggacactg gggccgctga aacaccaccg
    11341 cgtactccac ccggtgctca cacagatcca gcgctttatc caatagcggt ttatagggaa
    11401 tcaccccgga cggctcgatg ccacaagagg ccgacagcac cagcttgggc ttggcgtcat
    11461 cgatgcgact ggccagctcc ggcggtgcga acccaccgaa caccaccgaa tgcaccgccc
    11521 ccaggcgggc gcaggccagc atggcatagg ccgtttctgg aatcatcggc atgtagatca
    11581 ccactcgatc gcccttgccc acccccagat tggccatggc tccggccagg gtggccaccc
    11641 gctgctgcaa ctgctggtag ctgatcgcct cttcggtgcc cgtgaccggg ctaacgtact
    11701 gaatcgctac ctgctgaccg tgccccgcct caacgtggcg gtcgacggcg ttgtagcagg
    11761 tattgaggct ggcaccgggg aaccagcgat agaagggcgc atcacgatca tccagcacct
    11821 gatccaccgg ttgcatccat tcgatttgag tggcggcgtg acgccagaac gcctgagggt
    11881 tctgccacgc ctgctgctgc atctgcttga ccttatttaa cggcataggg cctccatggt
    11941 cgggattaac tgggtcaggc tttcagttgt agcagatgac ggccggcggc cccattcgac
    12001 catcggctaa cttctgacca gtcgcaacac aaactttacc tttacgtaaa cttcctataa
    12061 ggtgacttta agctagaaga gaccgatacc aagatgacag aaactacaga cgtgacctat
    12121 tccatcagcg agctggctcg tgaatttgac atcaccaccc gcagcattcg tttctacgaa
    12181 gatcaggggt tgatcagccc ccggcgccgt ggccagaccc gcatctacag cctgcaggac
    12241 aaagtccggc tgaagctgat cttgcgcggc aaacgtctgg gtttctcctt ggcggaaacc
    12301 ggtcggttgt tcgacctgta cgacgccgac aagagcagcg gcactcagtt gcataccatg
    12361 ctggagctga tcgaaaccaa gaaagcggat cttcaacaac agatggacga cattaaggtg
    12421 gtgatgatgg aactcagctc cgccgaacag caatgcaagc aagcactgca agagctcacc
    12481 gccgaactac aataacaggc gggccctctt ttgtggccgg agtgccacca gtcttgctgc
    12541 ccaaaaggaa ccaaggggag aagatatgag cctttaccaa tccagcttca attatggctt
    12601 gggagaaaca ctggagatgc tgcgggattc ggtccgggac tttgcccagg ccgagatcgc
    12661 gccgctggcg gcagacattg acagcaacaa cagctttccc aatgaactgt ggtccaagat
    12721 gggcgacatg ggactgctgg ggatcaccgt ggccgaagag tatggcggcg tcaacatggg
    12781 ctacctggcc cacgccatcg ccatggagga gatctcccgg gccagcgcct cggtgggcct
    12841 ctcttacggt gcccactcca acctgtgcgt gaatcagatc catcgtaacg gcagccacga
    12901 gcagaaagcc aagtacctgc cgaaactggt cagcggtgag cacatcggcg ccctggccat
    12961 gagcgaaccc aatgccggtt ccgacgtggt atccatgaag ctcagcgctc gcctcgacgg
    13021 cgatcactac atcctcaatg gcaacaagat gtggatcacc aacggccccg acgccgacac
    13081 ctacgtgatc tacgccaaaa ccgacaccag cgccggtgcc aaaggcatga ccgccttcat
    13141 cgtcgaacgc ggctttgccg gcttcagcca ggcacaaaaa ctggacaagc tgggaatgcg
    13201 cggctccaac acctgcgaac tggtgttcca ggacaccccg gtacccgtgg agaacgttct
    13261 cgggggcgtc ggcaacggtg ccaaggtact gatgagcggc ctggattatg agcgggtggt
    13321 gctggccgcc ggcccgctgg ggatcatggc cgcctgcctg gaccaggtgg tgccctacat
    13381 ccaccagcgc gagcagtttg gccaggccat cggccagttt cagctggtgc agggcaaagt
    13441 cgccgacatg tacacccgca gcaatgccgc ccgggcctac gtctacagtg tcgcccaggc
    13501 ctgcgatcgc ggcgaaacca cccgcaaaga tgccgccggg gccattctct acagtgccga
    13561 actggccacg caattggccc tggacgccat tcagttgctt ggaggcaacg gctacatcaa
    13621 cgagtacgcc accgggcgcc tgctgcggga cgccaagctg tatgaaatcg gtgccggcac
    13681 ttccgagatt cgccgcttcc tgattggccg ggaactgttt accgaaaccg cctaacgcac
    13741 gctctggcgg gggtcgcccc gcccgttaaa ggactgacaa ccgtgaccat actccgttcc
    13801 agcattaacc ggcaggagcc gggctttatg gcccggcgcg atgccatggc cgacctggtg
    13861 gccgatctga ccgccacact cgacgccatc gttcccggcg gcaatgaccg cgcccgcaac
    13921 aaacacctgg cccaggggaa actgctgcct cgacaacggg tcgaactgct gctcgatcct
    13981 ggcgccccgt tcctggagct cagccagctg gccgcccacg agtgctacga cgacaaggtg
    14041 cccgccgccg gcgtgattgc cggcattggc cgggtcagcg gcatcgaatg catgatcgtc
    14101 gccaacgacg ccaccgtcaa aggcggcact tactacccgt tgacggtaaa aaaacacctt
    14161 cgggctcagg aaattgccga aaaatgccac ctgccctgca tctatctggt ggaatccggc
    14221 ggcgccttcc tgccgcgtca ggacgaggtg ttcccagaca aggatcactt tggtcgcatc
    14281 tttttcaacc aggccaacat gtctgccaag gggattcccc agattgccgt ggtactgggc
    14341 ctgtgcaccg ccggtggcgc ctacatgccg gcgatggcgg atgaatcgat catcgtcaaa
    14401 gaacagggca ccatcttcct cggtgggcca ccactagtga aagcggccac cggcgaagag
    14461 gtcagcgccg aagagttggg cggcggcgcc gttcacaccc agatctccgg ggtggccgac
    14521 cacctggccg ataacgacga acacgcgctg caattggccc gtcaagccgt ggcccgcctc
    14581 aaccaccatc gcgcccagcc actggccgac accgacgttc gccccccccg ctaccccgcc
    14641 gacgacctgt atggcatcgt cggcagcaac ctcaaacagc cgttcgaggt acgggaagtg
    14701 atcgcccggc tagtggacga ctccgacttc gacgaattta aggccggcta cggtgccact
    14761 ctggtgtgcg gctttgcccg catctatggc cagccggtgg gtatcctggc caacaacggc
    14821 atcctgttct cggaatcggc ccttaaaggg gcccatttca ttgagctgtg ctgccagcgc
    14881 aacatcccct tgctgtttct gcagaacatc accggcttta tggtgggcaa gaagtacgag
    14941 cacgaaggca tcgccaagca cggtgccaag ctggtgaccg ccgtttcttg cgcccgggtg
    15001 ccgaaattca ccgtggtgat cggcggcagt tatggcgccg gcaactacgg catgtgcggc
    15061 cgcgcctacg accccaccat gatgtggatg tggcccaact cccgcatttc ggtgatgggg
    15121 ggcgagcagg ccgccaacgt cctggcccag gtcaagaccg acgccctggc ccgcaaaggc
    15181 gacagctgga gcgacgatga acagcaggcg ttcaagcagc ccatcgtcga gcagtacgaa
    15241 cgccagggcc atccctatta cgccagcgcc cgactgtggg acgacggcat catcgatccg
    15301 gcccagaccc gcgacgtggt cggcctggcc ctgaccgcgg caatgaatgc gcccaccgaa
    15361 gccacccgct tcggcgtgtt ccgcatgtaa ggagagtgaa atgacctttc aattcattac
    15421 cctgacccag agcgacggcg ttgcccgcct gaccttgaac cggccggaca agcacaacgc
    15481 cttcggtgac gccatgattg ccgagatcaa tcaggccttg accgggttga cccgccaacc
    15541 gccgaccctg ctggtgctgg cggccaacgg caagcacttc tctgccggtg ccgatttggc
    15601 ctggatgaaa agccaggcgg ccatggacca ggcctccaac ctcagcgatg cccgcgaact
    15661 ggcccgtctg atgcacaccc tggatcggtt tccggcgccg acgctggcgc tggtggacgg
    15721 ggccgccttc ggtggcgccc tcgggctcat cgcctgttgt gacatcgccc tggccagccc
    15781 ccgcgcccgt ttctgcctgt cggaggtcaa actcggactg attcctgcgg tgatcagccc
    15841 attcgtggcc cgggccatcg gccagcgcca gtcgcggcgc tacatgctgt ccgccgaaac
    15901 ctttgatgcc aacaccgccc atcagatcgg actggtgcat gaggtgtgcg acgatctgca
    15961 cagcagcagc gagcgcctga tcaccaccct gaccggcaac ggccctaagg cgatgcaggc
    16021 gtgtaaatcg ctgctgcaca ccatagagca gcaccctttt gatgacgcgt tgctggcact
    16081 gaccgccgac gccattgccc acatccgagt gtccccggaa ggccaggaag gcctgcaggc
    16141 gttttttgat aagcgcccgc ccctctggca aggagaatcc taatgttaac caaggtcctg
    16201 atcgccaacc gcggcgagat cgcctgtcgc atcattcgca cctgtcaggc tctgggcatc
    16261 cgcaccgtcg ccgtctactc cgacgccgac cgcaacgctc agcatgtcaa catggccgat
    16321 gaagcgtttc tgctcggccc ggcagccgcc accgagtcct acctgctggg cgataagatc
    16381 gtcgccctcg ccagcctggc gggcgtggat ggcattcacc ccggctatgg cttcctgtcg
    16441 gagaacccgg aattcgcccg cgcctgcgcc gacgctggca tcgcctttat cggccccaat
    16501 accgaagcca tcgaacagat gggctccaag agcgccgcca aggtgatcat ggagcgggcc
    16561 ggcgtgccga tgctgcccgg ctaccatggt gatgaccaga gtgaccagag gttgaccgaa
    16621 gaggcaacca agatcggcta cccgctgctg gtcaaggccg cctttggcgg cggcggcaag
    16681 gggatgcgca tcgtcgagca tggggatcaa ctggccgccg ctttggccac cgcccgtcgc
    16741 gaagcccaga gcgcctttgg caatgacatg ctgttgctgg aacgtttcct ggcagcgccg
    16801 cgacacgtgg aggtgcaagt cttcgccgat gcccatggac actgcattta cttgtcggat
    16861 cgggactgtt ccattcagcg tcgccaccag aaggtggtgg aggaagcgcc ggcaccgggt
    16921 ctgtccgaca ccctgcgcca gcagatgggc gaagccgccg tcaaggccgc caaagccatc
    16981 gactacctgg gcgccggcac cgtggagttc ctgctcgatg atcagggccg cttctacttt
    17041 atggagatga acacccgcct gcaggtagaa catccggtca ccgagatggt gaccggccag
    17101 gatctggtgc actggcagct gttggtggca tcgggtcaac cgctgccgct gacccagcag
    17161 caagttgaga ttcgtggcca cagcctcgag gttcgactct acgccgagga tccacagcga
    17221 gagtttctgc cggccacggg caccctgacc cgctttgagg tccccgcatc gctgcggctg
    17281 gacagcggcg tggtagaggg cgacgagatc agtcctcatt acgacccgat gatcgccaag
    17341 ctgatcacct ttggcgacac tcgcacccag gcgattcaac agatgagtcg cggcctgcag
    17401 caaacccagc tggccggagt caccagcaac ctggcctttc tggggcgcat cattaatcac
    17461 ccacagtttc aggccgccga cctcgatacc cgctttatcg acacccatta cgcccagttg
    17521 accggtgccg atgacttgcg ccacgtagcc gctatcgccg cagcgctggt gatcagtcaa
    17581 ccgggctgcc aacgcagccc ctggcactcg gtcgccggtt tccgtctcaa ccagagtccg
    17641 gtgatgcacc atcacctcga ggacgatcac ggcgagcgct acccgctgct ggtcaaaggc
    17701 cactggccgg ctctgacggt tcagctcaac gaggtggagt atcaggccgt catcggcatc
    17761 gatgacgatc agctgagcct ggagctggat ggccacttgt gccactggcc gttccagcgc
    17821 tgtggagaat ccgtgaccct gttcctgcca caaggcccac tgcggtttga tgccgtcagc
    17881 catcagggcg gtgacggcga cgacagcggc gaagacgccc tgaaggcacc gatgaacggc
    17941 accgtggtca ccctgctgtg cgaactggag caaaccgtcg aagccggtca gccgctgctg
    18001 gtgatggaag cgatgaagat ggaatatacc atcaccgccc cctacgccgg tcaggtgctg
    18061 gcactgccct atggacctgg ccagcaggtc aatgacggca ccgccctggt aacgctggaa
    18121 gccttggagg agtcatgagc cacgccacca tcgtcgaagt cgggccccgg gatgggctgc
    18181 agaatgaagc cgcagtcacg ctggctcagc gcatcgccct ggtcgatgcc ctctctggca
    18241 ccggcctgag tcagattgaa gccggcagct ttgtctcgcc gaaatgggtg ccacagatgg
    18301 ccgatgccga ccaactgttc gcccggattc agcggcgtcc gggcgttcgt tacagcgcac
    18361 tgacccccaa tatcaaaggc tttgacgcgg cgcaacaggc aaaggtcgac ggcgtcgcag
    18421 tgttcggcgc cgcctcggaa agcttcagcc aacgcaacat caactgctcc atcagcgaat
    18481 cgttgcaacg cttcgagccg gtatttgccg ccgcccgccg cgccggcctg ccggttcgcg
    18541 gctacgtctc ctgcgtgctg ggctgcccct atgagggcga catcgacgtc gccaaggtgg
    18601 ccgacgtcgc cgaatcgctg taccgaatgg gctgctacga gatctctctg ggcgacacca
    18661 tcggcgtcgg taccccggcc aaggccaaag ccatgttggc ggccgtgacc gaacggatac
    18721 cggtatcggc attggcgctg catttccatg acacctacgg ccaggccctg gccaatgtgc
    18781 tcgcctgtct ggatctgggt gtcaccacct tcgacagcgc cgtggccgga ctgggcggct
    18841 gcccctatgc caagggggcc agcggcaacc tggccaccga ggatctcctg tatatgctgc
    18901 atgggctggg catggatacc ggcgtcaacc tggacgccgt cattgccgcc ggcaccacga
    18961 tctgccgtca actgaacaag ccgccctcca gtaaggtcgc ccaggcctgg ctcgccaacc
    19021 ataaggagca accggcatga gcactcactc cccaatctgg caacccagcc agagccgcat
    19081 cgatgccagc cagatggaag cgtttcgcca cttcgtcaat gacaagctgg cgctgacgct
    19141 gagcgattac cagcagctgc atcgctggag taccgaccat ccggatcaat tctggcaagc
    19201 aatctggcag ttcagcgagg tgatcggcac gcccggtcaa cggctgttgc tggacggcga
    19261 taagatgcct ggtgctcgct tcttcccgga cgcccggctc aattttgccg aaaacctgct
    19321 gcgctatcag gacgaccgca tcgccctggt gtttcgcgat gaagccgcca accgggtcgc
    19381 cctgtcctat aacgagctgt atcacgaagt cgcccgcctc gcccaccatc tgcgtcacct
    19441 gggcgtggta gccggcgatc gagtcgcggc ctttatgccc aaccgcatcg aaactgtggt
    19501 cactatgctg gctgccgcca gcctgggggc cacgttcagc tcctgttcgc cggactttgg
    19561 cttcaacggc gtcctcgacc gcttcggcca gattcaacct aaagtgctgg tggccgccaa
    19621 tggctaccgt tacaacggca aagtcatcga ttgcagcgac aagatcgccc agattgccga
    19681 cgccatcggt tcgctgcagc aggtcatcgt ggtaccggcc ttcgatgcgg tcgctcaggt
    19741 tcagcatcca ctggccattg gctggcatca ggccctggat aacccggccc gcagcgtgtc
    19801 gtttacgcca ctgccgtttg accaccccct gtacgtgctg tactcctcag gcaccaccgg
    19861 gcaacccaag tgcatagttc atggcgccgg cggcaccctg ttgcagcacc tgaaggagtt
    19921 gcggctgcat accgatattc agcgtcgaga tgtgctgttc tatttcacca cttgcggctg
    19981 gatgatgtgg aactggctga tctccggcct ggccaccggt gccaccctgg tgctgtacga
    20041 cggcagtccg tttgccccag gcccggaagt gctgtggcag ctggccgaac aggaggaggt
    20101 ctcggtgttc ggcaccagtg ccaagtacat cgccgccctg gaaaaggccg gttaccggcc
    20161 ggcggaacac catcggctga ctcagctcaa agggctgctg tccaccggtt cgcccctggc
    20221 ccacgaaggc tttgattttg tgtatcgaca catccacccg gatctgtgtc tgagctccat
    20281 ctccggcggc accgacatcg tctcctgctt tgccctgggc aatcccatca agccggtcta
    20341 ccgtggccag ttgcagagtc ccgggttggg aatgaaggtc gaggtctata acgagcaagg
    20401 ccagccgctg caacagcaaa aaggggagct ggtgtgcacc acgccgttcg tgtcgatgcc
    20461 catcggcttc tggggcgatg acgatggcag caactaccac cacgcctatt tcgaccgttt
    20521 cgacaacgtc tgggctcacg gcgactacgc cgaaaccacc gccgagggtg ggctgatcat
    20581 ccacggtcgc agtgatgcgg tactcaaccc gggaggggtg cggatcggca ccgccgagat
    20641 ctaccgccag gtcgaaaagg tggaccaggt acaggaaagc ctggccatcg gtcaacagtg
    20701 gcaggatgac gtgcgagtgg tgctgtttgt ggtgctcaaa cccggcacca ggttgaccga
    20761 tgcattgcag cagcagattc gcaccaccat tcgcgccaac accaccccga ggcacgtgcc
    20821 ggcgaaaatc attcaggttc aggatctgcc aaaaaccttg tccggaaagt tagtggagtt
    20881 ggcagtgaga aaagtggtcc acggtcaggc ggtcaccaac accgacgcgt tggccaaccc
    20941 tgaatctctg caacaattta agcacctgcc agatcttcag tgttaacgca aagaatccag
    21001 tcacaactgt atttttacat atgtgactgg atttttaccc atcttttcag aagcttagac
    21061 tttccgaaag cgccaaattg ctcgaaaaaa gcgagcaatc caaccattgc ttaaaacacg
    21121 atattaataa aaaaagctta taaagcttct cttaaatcaa acagttagat catcaaagaa
    21181 aaagtgtgaa ctgctaccaa acccccacta ttgcacctac tcgctcatgc atgttagatt
    21241 ccgcggccag atgaatgtct aaaacttgac taagatttat taatataatg aatttagtca
    21301 gcgtaagttg gaaagtacta tgccagtgtt aatgcgtgac tttgattcga ttgatatacg
    21361 actgctcata gtgttccgcg cagtggtttt taccggtagc ttaagcaaag ccgcccggaa
    21421 actgtccgta acgcctagtg ccgtcagtca atccctgtca aaactaagta aatacttcag
    21481 ccacccactg ttcacccgaa ccagcaatgg actggaaccc accgatttcg cgatggagct
    21541 gtacggctac gttaactcgg ccctggatct gctgcaggac ggcgttgaaa gcctgagcga
    21601 cttcgatcca gccaacagca aacgtcgctt tagaatctcg gccaaccaca ttcttgacct
    21661 gatcattctt cacccgctgg cccgccacat cgagtccttt aacagtcaac tcaaggtgtc
    21721 ggtcaataac ctggtggaag aggaatcgaa gatcatcgac agcctgcaga tcgacaacaa
    21781 cgacctgtgc ctggtggcga tgaagatcga catgaagagc atcattcagg agaaggtgct
    21841 ggacgaagag atggtggttc tgggctgcaa atccaacccg ttgaccaaag aggtcatcga
    21901 catggacacc ttcctggctc agcgtcactg ccgttacgcc gtcggccaga ttggctacaa
    21961 gatgggcaac gccatgaaca tgggttacgt cgacgaacgg gaagtgttcc tggacaccaa
    22021 caaccccttc aacgccatga tgatgactca gggcaccgac accctggtga ccatctcccg
    22081 ctggttgtgg gaaaagtacg ccagccaatt cgaactggca gagattaaga ccagcttcga
    22141 cattccaacg gtgccgctgt atctgaccta tctgaagaag atggaagaca gcaaggccaa
    22201 tcgctggttg cgcgaccagg tcaaacagac cctcgcttca ttgcgttaac accgaattgc
    22261 gggaatggat tcctgcccct ctccccagct tcaaccttcc ctttctgcca ggcaaaaaaa
    22321 agccggcaca taccggcaaa cccacactgc gctagcaact taaaactgct ttaaatttag
    22381 cagcggttta ccagcttgca atattcgggc gtattttcag ccgagagtgc cccaccggtt
    22441 cgatgcgaca ccccctgatt catcgatgct cagtcccagg ccaactctcg ataatgggtc
    22501 cggcacatgg agacataact gtcgttacca ccgatctgta cctggtcacc gttgcgcacc
    22561 gggttgccgg tttcatccag ccgaaccacc atgttggctt tacggccaca gtgacagatg
    22621 gtcttgagtt caaccagttt atccgcccag gccaacaggt attgggcacc ttcaaacagc
    22681 tccccctgga aatcggtgcg taagccgtaa cagagtacgg gaatgtccat cttgtccacc
    22741 aggtaggtca attgacgcac ctgactcttg gtcaggaact ggcactcatc caccagcaga
    22801 caattgaccg cttgagcgtc attctcccgc aataccatct ggatcagatc atcctctttg
    22861 cggtagataa gggcatcgga cgacaacccg attcgcgacg tcacttttcc ctgaccgtaa
    22921 cggtcatcca ggcccgcggt catcaccaga acctgcatgc cccgttcgcg gtagttgtac
    22981 gccgattgca gcagagaagt ggattttccg gcattcattg ccgaatagta aaagtagagt
    23041 tgagccaaaa ttgatccccc agtaatcgct gaggcaagtc taccgaaaag cccggatctg
    23101 aaccagagtg gtggggcaaa aaatggcggc ggcaaacgca aatcgggccc ctggtggggc
    23161 ccgatgtgtt agcggattaa cctcagcgcc gacacaggcg tttcagcagc agaatcacca
    23221 gcaccagccc cagggtggcg gtggcaaacc cggccatgac cgacccggtc atccccagta
    23281 ccaggtaacc ggccagcgag atcagtgcgg tcagcaccgc atagggcaac tgagtagtaa
    23341 catgatcaat gtggtggcat ccggcaccgg tggaggacag gatggtggtg tcggagatcg
    23401 gcgaacagtg atcgccgaac accgcaccgg ccagtaccga agacagcatc ggcagcatca
    23461 gtgccagatc caccgcttcg gccatgttgg cagcaatggg cagcatgatg gcgaaggtgc
    23521 cccaactggt gccggtggca aaggcggcaa agccactgag caaaaacagc aacgccggca
    23581 atccccaggc aggcaggttc ccctgggcca gagtcgccat gaattcgccg gtcttcatgt
    23641 cgctgatcac cccggcaatg gtccaggcaa acagtagaat gtagatagcc ggtagcatcg
    23701 atttgacgcc actgatcacc gccttactca tgtaagccgc cggcaccccc tggcgcaaac
    23761 cgaacagcag ggtaaagccg accccggcca ggccagagta gaacagggac caggcgacgt
    23821 cggtgttttc aaaggcaccg ataagggaga acgccttgtc gtccgccgcc aaaacctggt
    23881 tgccggaaaa cagcatcaaa gaaaccgtta tcgcaatcag gaaaccgatg ggggccacca
    23941 ggccggcgac ccggccattg ttggcctcgg gcaggtccag ctcttcaccg gcaggcaccc
    24001 ctttggcttc gtcccacagt tgaccgcgct gagctcgctg ctcggcgtcc gccatggcgc
    24061 cgaaatccag gccgaaatag accaccgcca gcaacagggc aaaggcaaag atggcataga
    24121 agttcatcgg taccatctgc ataaaggcac tcaggtaacc gatgtcggtc atgccatggg
    24181 tggtgagcaa gcccccgatc agggcgatga tgtacgcgcc ccaggaggag atcggtgaga
    24241 tcacgcagat gggcgccgag gtggagtcga tgcagtaggc cagcttttcc cgcgacacct
    24301 gatagtgatc ggtcaccggc ctggccaccg agcccaccac cagagtgttg aagtagtcat
    24361 cgatgaagat caccaccccc agtgccatgg tcatcaactt ggcatcgcgg ccgcagcgga
    24421 tgcggtgacg ggcccaatcg gcaaaagcac gggtcgcccc ggagaccgaa atcagcgcag
    24481 tcatcacccc cagtaacacc agaaaaccaa gcgtgtagag attccagctg ttgagggcgc
    24541 cgtcatccca aaccagagag acggcacggg aaccgagctc ggaagcgcca tcaaccacag
    24601 agaaatccac cagcatcagg atgccaatgg caatgcctaa ccccagggac agcagaactt
    24661 ttcggctggc gattgccatg ccaatggcca ccacgggggg cagcagggag agtgccgaat
    24721 cggcgtaact aattaaagcc atcgtaatgt tatcgtcatt attagcgatg gaggcaactg
    24781 acacggccaa agccgcgggg gactagcaaa aagcgagaga tccaccttcc attcagtagc
    24841 gctccatagt aaatcatctt cccaacatcc ggttggaatt tactatggca gtgttactcc
    24901 tgttagaagt aaccccagcg cgcagggatg atgcccggca cacttcggca tcgactcctt
    24961 tgggccggcg tcgtcgggta tcaacctcga ccggcttact gataggcgat gcgcctctac
    25021 cttatcggta ctcgcatacg aagatgcgaa ggcggcattc taactgcaag tgcccctcac
    25081 ttgaccagca gatgccgcca tattgtgagt tatatcacag ttataacagt tctgtgagct
    25141 tagggacagc gtcaaacaga tccgcttcca gtccataatc ggccacctgg aaaatcggcg
    25201 catccgggtc cttgttgatc gccacgatca ccttggactc cttcatgccg gccaggtgtt
    25261 gaatggcacc ggagatgccc accgcgatgt acagctcggg ggcgacaatt ttaccggttt
    25321 gtcccacctg caaatcgttg gctacgtagc ccgcatccac cgccgcccga gaggcaccga
    25381 tggctccacc gagcttgtcg gccagggctt cgatcaaagc aaagttctcg ccgctgccca
    25441 aaccgcggcc gccggagatc accacccgtg cggcgccaag ctcaggacgc tcagactgca
    25501 ccagctcttc gccgacaaac tggctgaggc cgctgtcttt gacgctggac accgtctcga
    25561 tgtctgccgc cgcctgagtg gcaacggcat cgaacgcgct ggttcgaatg gtcagcacct
    25621 tgatggcatc caggctttgt accgttgcca gggcattacc ggcataaatc gggcgcacaa
    25681 aggtgtcttc tgactcaatg gcaataacat cggagtgctg agccacgtcc agcaacgccg
    25741 ccgcccgcgg cagcacgtct ttgcccttgg cactggctgc ggtcaggatg tggctgtagc
    25801 caccggccag ctccagcacc aggtcggcga ccggttctgc cagctgatgg gcatacccat
    25861 cgtgatccgc cagcaacacc ttggtgacgc cagccagttg tgccgcctga ttggcggcct
    25921 cggccacgcc gctgccggcg accaatacat gaatctcctg acccagttga gtggccgcac
    25981 ccacgacttt ggcacactcg gcacccaggc cctgtttgtc cagctctgca ataatgagga
    26041 tcgccattag accaccttcg cttcgttttt cagcttctca accagctctt caaccgagcc
    26101 caccatgatg ccgccactgc gttccgccgg ggccgttacc tttattacct gttggtggga
    26161 tttcaactgc aactcgaaat ccgccactgt aacggtgtcc agtggtttgc gcttggcctt
    26221 cataatattc ggcagcgacg catagcgcgg ttcattcagg cgcagatccg cagacacaac
    26281 ggcaggcagt ttgacactca gggtttgaat gccgccatcg atctcccggg caacagtgac
    26341 ttgatcgcct tcgacctcaa tgctggaggc aaaggttgcc tgccccatgc ctgccagtgc
    26401 cgccgtcatc tgcgcggtct ggttgttgtc gccatcgatg gattgcttac caaacagcac
    26461 caaatcgggt tgctccttgt caacaaccgc ttttaacacc ttggcaatcg agatgggcgc
    26521 caactcttca tcgtgctcca ccagaatccc gcgatcggcg cccaaggcca tggccgtacg
    26581 caattgctcc tgggccactt taggaccgat tgataccgca ataatctcat cggcctggcc
    26641 tttttccttt agccttaccg cttcctcgac ggcgatctcg cagaaggggt tgatcgccat
    26701 cttcaggttg gccagttcca ccgctgactc atcagcagcg actctcacct tcacataggg
    26761 atcgaccacc cgcttgatcg gaaccagaat cttcatagta cgtcctttgt ttagcgccag
    26821 aatcgacttt gcataacact gcctcccact ctaattactg ttaacgtaaa cgtcaacatt
    26881 caaaggccgg cagcagggtg aaaatgaaca gaagctgaac cagtgacatc gaaggacatt
    26941 tttttcaatg acacggaact cctgaataat gtaaatgtct gcaaagatat cgatatatca
    27001 tcttagtaat gagtaattaa ttgtcttaat ttacgagaca actataattg cccatgctaa
    27061 tctaaacact gttaaatttg cacacttgat aattaggttg aatccacgat ggctgatttc
    27121 ttagaaattt tgactcacgg tcgccgctta aaggctcaag ttaaagagct agagctggat
    27181 gagctgaaag atgtaatcgc taaactgcag aaaattgcag acgagcgcga agctgaagca
    27241 gaggaagaaa ttgctgctca agctgaacgc ctggctaaaa ttgaagcaat ccgcaagcaa
    27301 cttgcagaag atggaattag cgttgatgag ctaaatgcac tggaaagtgc ttctccacgt
    27361 cgcaagcgtg caccacgccc agctaaatac aagattgttg ttgatggcga aaccctgact
    27421 tggaccggcc aaggccgcac tccaaaagcc atcaaagaaa aactggatca aggtcactcc
    27481 ctggaagagt ttctgattta agatttagtt acaaagtttc ctaaaacggc tgccaatggc
    27541 agccgttttt ttatgcccgc ttgccgaagg cgaattgcag cccctcgtcg atgcaaggat
    27601 aatggattcg attcaggaat aataaaacaa aaggattttt gaatgcctct gcccacaact
    27661 cattggcgtt ggcggcggct gtgtcaggtg ctcgcctgcg ccgccagcct gccggcattt
    27721 gccagcccca ctcaacccgt cagcgccatt gccaatgccg atgatcacta cctggccttt
    27781 acccatgcca ccttaatccc cactcccggc cagcgactcg agaatgcgac gctggtgata
    27841 aaagatggga aaattgtttc tatttcagaa agtaacaagg ttccagacgg ggcaagagag
    27901 atccattcca ggggaaaaac catctatccg ggctttattg acccctatac cgactttggc
    27961 caacagtggc agtattccga ctaccccgac ggcgggcctc actataatgc cgaacaagcc
    28021 ggcgccaagg taaataaccg ggccatccac gccgaaatga actgggcgga ccatttccaa
    28081 tttgatcatg aacgcgctca agattggcat aataatggct tcacttcggt acaaaccggc
    28141 aaactcgacg gcttatttca gggcatgagt gcaacggtct ccctcattga ccttcattct
    28201 gaaagcagta tctatgccat cgaaggcgct cacctgatgt catttgacaa gggaagttct
    28261 gagcaagaat acccaaactc gctcatgggc agtattgcgc ttattcgaca aacgttaaaa
    28321 gatgcacagt ggtatcaaca gcaatccagc aaatcaatac ctcagttatc gttaaacctg
    28381 aatcaaacct ttaccaaact gttacagttt aacaatcaac gaatcatatt tgacccagga
    28441 caaggaaaca acgcctcccg cgcgctgcaa ctgttgcaac catttcatcc ttcgccggta
    28501 ctcgtgggca atggtttaga gtttgagcga ctggagtcgc tgaaacaaac tcggcttatc
    28561 ttgccattaa ctctggctgc aaaaccgcca ttggatgccg gattggatat tagccttaaa
    28621 cagcttcgtc attgggagcg cagtcccggc aaccttgcgg cagtcgccgc cgccaatatt
    28681 ccctttgcca tcactcagca tggaatcgat ccactcgagt tttggaaccg aataaccaaa
    28741 gcggtggaat atggactgcc caaatccacc gctttggccg ccttgaccac cgtcgccgct
    28801 gaatatgccg gcgtcgatga cttccttggc caactgcaac ccggctttca ggccgatttg
    28861 gtgatcgcca ccggtgacct gtttgccgga gccgagattg aaagcctgta cctcaagggc
    28921 cgacctctgc cattgaatcc gcaactgggt agtcggcttt cgggtcaata tcagttgtcc
    28981 attgatgaga ccgacctgac gctggttctg agccaggatc agggcgaact ctccgcccaa
    29041 cttgaaagcg gcgaacggct gattctgctg gacgtctccc acagcgcggc ggaacagttc
    29101 agcgccgtcg ccgatctgac ggaactgggc ttacccggat taacccggtt gaccttgcac
    29161 cgggtccgcc aaggattgtt tggcaacctg acccagcacg acggtcaact gctgccgctg
    29221 gcagccagct atctgggtcc gatagccacg agcaccgaac cggagccagt gacaacaccg
    29281 acctacctga gccgtctgac tcgaccgaac cgggccttcg gtaccgacgc ccccctgcag
    29341 caggaacgac tgcacattcg cggggccacc ctgtggaccg ccgctgacga cggcatcatc
    29401 gccgatgccg atctgctgat cgacaatggg gtgattcgcg ccatcggcga gaacctcacc
    29461 accccagaag gcttcgacgt cctcgatgca cagggcaaac acctgacccc cggctttatc
    29521 gatgagcaca gccacatcgc cattcgaggc ggtgtcaacg aagcgtcaga cagcaacacc
    29581 gccgaagtcc gaatcggtga cgttctcgat gccgacgaca ttcacatcta ccggtcgttg
    29641 gccggagggg tcaccaccgc tcaattgctg cacggcagcg ccaacgttat tggtggccag
    29701 gcccaggtga tcaaactgcg ttggggcgaa tccgaccatg acctcaaatt tcaacaggcc
    29761 ccagccagca ttaagtttgc cctgggtgaa aacgtcaaac agagcaattg gggtgatcgt
    29821 tacgtcagtc gctttcccca aacccgaatg ggagtagaag cctacctgga ggatcagttt
    29881 gaacaggcca ggaaactgca acgtcagcaa caggcctacc aaagcctgag tcgtaaccag
    29941 aaacggcgcc aattggcccc gcgccccaac gaccggcttg aggccctgat cgagatactg
    30001 aacggcagcc gcaacattca cgttcattcc tacgtgcaat cggaaattct gatgttgctg
    30061 cggttgtcgc agcggctggg attccacgtt cagaccttca cccacatcct cgagggctac
    30121 aaggtggccg atgagatggc cagctatggc accagtgcgt ccaccttttc agactggtgg
    30181 gcctacaagt ttgaagtcta tgatgccatt ccccacaacg cctgcctgct gctgcagaaa
    30241 ggcgtcaaca ccagcatcaa ttcggacagc gccgacttga ttcgcaagct caatcaggaa
    30301 gccgccaaat cgatgatgta ctgcggcatg agcgccgaac aagccctgaa gatgatcacc
    30361 atcaacccgg cccggcagct gaagattgat cgctacaccg gctcactgga aacgggcaaa
    30421 caggcggatc tggtgctgtg ggaccaaccg ccgatgtcgg tgtatgcccg ggtggagtcc
    30481 acctgggtgg atggcgtgcg tcgtttcgac cgccagcgcg atcggcaact gcagcgtcaa
    30541 gccggagccg aacgtcaggc cttgattcag aaactgctgc tcgatgacag cgatgacggg
    30601 gagggcgaat cgctcacccc ggacgaggtg ccgctgtggc actgcgacag cctcatccac
    30661 cagcattaag gagccgatga tgaaaaccct gtataccttg ctactgctgg ccctaggtag
    30721 cccggcattg gccaccgccc tgatggttgc gccgccccag tctcaaccga tcctgattca
    30781 gggcggcacc ctgcacaccg tcacccaggg cgtattgccc aacaccgacc tgctggtgga
    30841 agcgggtcgc atccgcgcca tcggtaccgc actgcccgtg cccgccgatg cccgccttat
    30901 tgacgccagc ggccaacgag tgtacccggg cctgatcgcc ctggccaaca ccctgggcct
    30961 ggaagagatt gagatgatcc gttcca
//
