LOCUS       NZ_CP072679            10960 bp    DNA     circular CON 26-AUG-2024
DEFINITION  Ferrimonas sp. SCSIO 43195 chromosome, complete genome.
ACCESSION   NZ_CP072679
VERSION     NZ_CP072679.1
KEYWORDS    RefSeq.
SOURCE      Ferrimonas sp. SCSIO 43195
  ORGANISM  Ferrimonas sp. SCSIO 43195
            Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
            Ferrimonadaceae; Ferrimonas.
REFERENCE   1  (bases 1 to 4795900)
  AUTHORS   Tang,K. and Wang,X.
  TITLE     Antagonism between coral pathogen Vibrio coralliilyticus and other
            bacteria in the gastric cavity of scleractinian coral Galaxea
            fascicularis
  JOURNAL   Sci China Earth Sci 63 (1), 157-166 (2019)
REFERENCE   2  (bases 1 to 4795900)
  AUTHORS   Tang,K. and Wang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of
            Oceanology,Chinese Academy of Sciences, 164 Xingang West Rd,
            Guangzhou, Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023716685.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 05:47:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,431
            CDSs (total)                      :: 4,267
            Genes (coding)                    :: 4,241
            CDSs (with protein)               :: 4,241
            Genes (RNA)                       :: 164
            rRNAs                             :: 10, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 131
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 26
            CDSs (without protein)            :: 26
            Pseudo Genes (ambiguous residues) :: 0 of 26
            Pseudo Genes (frameshifted)       :: 7 of 26
            Pseudo Genes (incomplete)         :: 17 of 26
            Pseudo Genes (internal stop)      :: 5 of 26
            Pseudo Genes (multiple problems)  :: 2 of 26
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:33:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1975295
            Orig. end                         :: 1986255
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072679.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10960
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="4"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10960
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10960
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5960](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5960
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(913..927)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            931..2658
                     /locus_tag="J8Z22_RS09330"
                     /old_locus_tag="J8Z22_09310"
     CDS             931..2658
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J8Z22_RS09330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J8Z22_09310"
                     /product="hypothetical protein"
                     /protein_id="WP_028113414.1"
                     /transl_table=11
                     /translation="MKKLALATVVAAAAVGAYIYTQQPQSAASGMASFVPADTVWFSAQ
                     ETPFPIRAYLRASAASYQLSDSEMQQLQQSLQQAKDVDEKFFLAFLLNYLQGLQDPDQL
                     VKDYGLGDTVRFYTYAIGAAPVFKWQVENPQAFWQTLGRIEADSGAMHNTRTIGGIEAR
                     VYDLALDDVDEQLELWFAEVDGMMTMVIGAPLLDASQLAIAFAQARPAQALADTGILDE
                     IRQRNRFSSGDIGYISHQQLLTGLMTPSGNTMAKQINRLADDPQELAKLQDPICYQELS
                     GIVVNWPRTVFQTRIEALGDGFSISSDTIIESRNQPMLSALNKLRGFVPQSLFDATKPM
                     FAAALGINADTLQEGLVEVRDQMLDVSYQCPQLAQLQQELKQVPPESLALFSGFTDGIQ
                     GLGLGVYDYAFDESRSDGTLSTYSLLMSVSAKDPTKAFNAIKMVSPEFASLDLKPGQQA
                     VDIKDRVPQLQYALQPIMLEMSESQLMLHTGDKGARVAEAMSAEPLTANGLMAVTMDYQ
                     QAMLPAMDWAKALDPELVNQLKSMQSYHLIMKLMLDVDDRGLVFHYQGDSDPNRLKAK"
     misc_feature    complement(2740..2752)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.2"
                     /tool="antismash"
     gene            2934..4958
                     /locus_tag="J8Z22_RS09335"
                     /old_locus_tag="J8Z22_09315"
     CDS             2934..4958
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024306.5"
                     /locus_tag="J8Z22_RS09335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_09315"
                     /product="ferritin-like protein"
                     /protein_id="WP_252010177.1"
                     /transl_table=11
                     /translation="MYFENAVRQHLQANPALQQRAIHNRPADVAAVRALAQAAVNVELF
                     TIPLYMTAMYSLQGMHAITGDNALYKGRLWPGMSTSAKVQTANQQCFNTIFSVFIQEML
                     HLQLASNIFNALTKNAPENQCSPCFTSPLLQDPGTLGWHCYGETKTTIPHIINLKDTTV
                     YQSVTVSLGEVNDNTVALFLAIEEPADVLQTLILDSKRGDYLVTKGPLSEQVPFDGWTA
                     DNTEKDLPMFGTIAAMYECLALYLNLEYSDGTTLIEALYKPDSIQNDLFNTESEGHCSP
                     EFPHLNTVIDAGSAVEAKAQILTMMDAITDQGEGSTLKVQGPQVAVRPQGMVGDAVKPN
                     YQPDFNALKNDYVSYNDDGQKVESADAHARFFGGVVDHYDRFQQVRGLLESGQLTTWSQ
                     WHNASDQPRSWQASMLELEGAAPIAGIPTAEEVAGALNRLNAPDSRDGNLELFSRVAAG
                     AIAGITTVLNDYWSTPNTDFPFPSMAGSGDRISICWAVFGQAPDLSLGQFERHSGDSAP
                     LYHACQGLDYGDSAEGNQCASKEVFHTCRGSNACKGEGGCGFVQSTKGGSGCNAMVAKT
                     GDDELYTAPGDNFCGSYGGCAVPISASQRFPKSGTMALYQLFADKDSVKLEQTLSFDEG
                     DSVYATAWKAYEKVMASEGKPAGNAPEASDLRLAFPPST"
     gene            5001..5960
                     /locus_tag="J8Z22_RS09340"
                     /old_locus_tag="J8Z22_09320"
     CDS             5001..5960
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010370012.1"
                     /locus_tag="J8Z22_RS09340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_09320"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_252010178.1"
                     /sec_met_domain="DUF692 (E-value: 1.8e-89, bitscore: 297.5,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQITTELGLGVGLRSCHFSWLMAQRDSAALGVDWLEIITENFLD
                     NYGYARHVLLTLRERLPMAMHGVSLSIGSTDPLNVEYLYKVKRLADELQPALVSDHLCW
                     TGLQGINSHDLLPMPLTRESLNHVCVRVAQVQEILDRPLVLENPSSYLAFSENEFHEWE
                     FLNELCARCGCALLLDVNNVYVTCSNLGWDAQAYLDGIDAANVVQCHLAGPTDCGTHLV
                     DTHDQPVPTPVWQLYRQLVQRTGPLSTLLEWDDRIPPFPELVSEVQLAREVLAGRIPDV
                     VPTSATQPLSTPLHTTVTAHEPIEPETSAELVATANSD"
     gene            5902..6708
                     /locus_tag="J8Z22_RS09345"
                     /old_locus_tag="J8Z22_09325"
     CDS             5902..6708
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021364.5"
                     /locus_tag="J8Z22_RS09345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_09325"
                     /product="DNA-binding domain-containing protein"
                     /protein_id="WP_252010179.1"
                     /transl_table=11
                     /translation="MNPSNLKHQQSWLLQRILTNRWSGDSPLAYPRAEFGDQQGTLVYQ
                     RGYRLRLIECLKAEFPLLRRYLGEETFGLFAMGFLEFKPSSSYTLFDLGQSFTHYLKLT
                     QPKQANFEPWRWRLPGQLAQVETAQSQVARAQGLESNEPSLLPLPLWQLPPVWVPPTTR
                     VFECDLDMMALMAQLSRQQVATPRPGRQQLMLYRHRYRVHRRPISALQATVLAALKSGQ
                     PWSRALELAQCNSAMTESERVAEALSWLPQWLTEGVVGLDKPADRA"
     gene            6792..7733
                     /locus_tag="J8Z22_RS09350"
                     /old_locus_tag="J8Z22_09330"
     CDS             6792..7733
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1125: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.5"
                     /locus_tag="J8Z22_RS09350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_09330"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_252010180.1"
                     /transl_table=11
                     /translation="MRHNLNQLRVLSALLQQPNLTRVAERLHMTQSAVSKTLHQLRQDF
                     DDPLLVREGQRYLLTPKAQSLQLTLPQQLQQLDALYLPQSFDPSLCQRTLVFSSSDYVA
                     QHIFPAIAAEVARQAPLVTLEYRLWDKGQLSQLASLPVDLVSTIVESVPDNVARRDQGE
                     DGLAVLMSADHPLAEQTLTLERYLQFEHLRVSGGGDKDSPVDTALQALGHRRRCFAQVP
                     FFQSALGLLMSTPTLLTTPLHIAAQMSEQAPMVVKRLPFDCARQHYRLLWHRRFNEDPA
                     HRWFRELAFPFLCDHLNHYVQKGITKTTCRHE"
     gene            7810..8415
                     /locus_tag="J8Z22_RS09355"
                     /old_locus_tag="J8Z22_09335"
     CDS             7810..8415
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013344740.1"
                     /locus_tag="J8Z22_RS09355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_09335"
                     /product="LysE family translocator"
                     /protein_id="WP_252010181.1"
                     /transl_table=11
                     /translation="MTFLTWLPLATVCVLGALSPGPSLALVINNTVQRGTATGLRTALG
                     HGIGVALYALITAMGLGLLISQTPWLFDGIKYAGAAFLVYMAIKILLAKPNVEGQSRSR
                     KTRFVGFGGGFMVAFLNPKLAIFFLALFSQFVRADLTLGDQLLMMATAGGIDALWYAAV
                     ALGIGRTGLLGWLQRHGIWVDRVSAVIFLLLATAVVLQ"
     gene            complement(8732..9898)
                     /locus_tag="J8Z22_RS09360"
                     /old_locus_tag="J8Z22_09340"
     CDS             complement(8732..9898)
                     /EC_number="6.3.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013345762.1"
                     /locus_tag="J8Z22_RS09360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_09340"
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="WP_252010182.1"
                     /transl_table=11
                     /translation="MQRHLITPRTNWQQQAETYGFNFHTMYGEPYWDESRYYAFTLDQI
                     ERDLEDPTTEINQMCLEVVDKVVQDDALLRKFAIPEAHWEMIARSWRLKDPALYARLDL
                     AYDGSGPAKLLENNADTPTSLYESAFFQWLWLDERLKDGTVADGSDQFNSIQEQLIARF
                     AQLKQSWPPVPLHFACCQDTDEDRGTVQYLQDCAEEAGLQTLFTYIESIGITPQGGFVD
                     GDSRPMHAAFKLYPWEFMLREEFGDYIDKAQTRWLEPSWKSVLSNKALLPMLWKLFPNH
                     PNLLPAYFADERHLANESRLVEKPIYSREGANVRILDGNQSIADSDGPYGEEGVIYQAF
                     QDLPKFGDDYALIGSWLVGDEAAGISVREDHSLITQDLSRFVPHIILP"
     gene            complement(9898..10596)
                     /locus_tag="J8Z22_RS09365"
                     /old_locus_tag="J8Z22_09345"
     CDS             complement(9898..10596)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018408.5"
                     /locus_tag="J8Z22_RS09365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8Z22_09345"
                     /product="DUF1190 domain-containing protein"
                     /protein_id="WP_051252709.1"
                     /transl_table=11
                     /translation="MKRSRSILSPRFKKQLTVPTAAAISVSLTLTGCSPEPMQETAQVY
                     RNVTECIQVNPGQDQLCQSVFGEAQALAEETAPRFNSLADCELEFGAEQCTGGGDFATD
                     LAGDVNTLADGEQYADNGGGGGWFMPMMYGYMLGNMLSGSRNKYRTAPVYSSKNARSPL
                     NGKLVTGAGDVVGRSGDRVVRTSPNNFTPKKATNVTQRGGFGKMAQVKSAQAAKARSSA
                     RKSSSRGWGG"
ORIGIN
        1 tgggcggcta tcgagcggta tttgcggcgc tgctgattac ggcgttgatg ttagtggttc
       61 tgaccctggc tcgcttgcca gagactcggc catcactgca ttcgaatgcg ccgctgcacc
      121 gagtggcggc cgccatggcg gccgacccga aaatctggtg cttcggcgcc ctggtgtctc
      181 tgttcaacct gatgttgttc agttacttct ctctgggtcc ttttctgttt gagactctgg
      241 gcttaagttc tgcccagttt ggtgccagtg gcgtggtgtt ggcactggga acggccatag
      301 gtggctggat aaaccgaact ctgctcggtc gtgaatggtc atcgctgcaa ttgcttcagg
      361 tcgcgtcttt ggcgacgctg cccgcagccg ccggagtctg gctgcttcag gggaccccct
      421 ggttgttgct gccgatgatg atggtcgtga ctggttttgg gatcgccatt cccaatgtgt
      481 tgggcctggc gttggctgac taccgacagg tggccggcag cgccggagcg gtgtttggcg
      541 gcggctatta tctgggactg ggcatgggaa tggtgtgggt ggcgcagttg cagaacttgg
      601 gggcggtgct gtccatcagt gcctgtgcgg ccttggtgtt caccttggtg gtggggcgtc
      661 tcggccgagt tagtcgctgt tcagcctgat ttcgctacac tgattcggtc cgttaccgcc
      721 gtgagcttaa aggcccgagt gtggccattt gccatcggca gcgattttct tggactggtg
      781 attgggcctt tgctactgtc ctatatagga taaatttcaa tgacttccta ttgtattttg
      841 acactatagg ggcattactt accatcgtcg ttgacccggg aacaagtggt gtccccggag
      901 tgtatcggcg gcatcgacag gggaaatagg gtgaagaaac tggcattggc aacggttgtc
      961 gcagcagcgg ccgtcggcgc ttatatctac acgcagcaac cgcagagtgc cgcctcaggg
     1021 atggcgagtt ttgttccggc ggataccgtt tggttttcgg cccaggagac cccgtttccc
     1081 attcgggcct acctgagggc gtcggcagcc agttaccaat tgtctgacag cgagatgcag
     1141 cagctgcaac aatcgctgca gcaagccaag gacgtggatg aaaagttctt tttggcgttc
     1201 ttgctgaact atctgcaggg tctacaagac cctgaccagc tggtgaagga ctatggtctc
     1261 ggcgacactg tgcgcttcta tacctatgct atcggtgccg cgccggtgtt taagtggcaa
     1321 gtggagaatc cgcaagcgtt ctggcagacc ctgggccgaa ttgaggccga cagcggggcg
     1381 atgcacaaca cccgtaccat cggcggtatt gaagcccggg tttatgacct ggcgctggat
     1441 gatgtggatg agcagctgga gctgtggttt gccgaggttg acggcatgat gaccatggtc
     1501 attggcgcgc ccttgctgga cgccagtcaa ctggccatcg cttttgctca ggctcggccg
     1561 gctcaggcgt tggcggacac cggcatcctg gatgagatac gtcagcgtaa ccgcttcagt
     1621 tctggtgaca ttggctacat cagccaccag cagttgttaa ctgggttgat gaccccatcg
     1681 ggcaacacca tggccaagca gatcaatcgc ctagccgatg acccgcagga gttggcgaaa
     1741 ttgcaggatc caatttgtta tcaagagctg tcgggtattg tggtcaactg gccaagaacc
     1801 gtgttccaga ccaggataga ggcgttgggc gacggtttta gcatcagcag tgacaccatc
     1861 attgagtcgc gcaaccaacc gatgttgagt gcactgaata aactgcgtgg ctttgtgcca
     1921 cagagcctgt ttgatgccac taagccgatg tttgcagcgg cgctggggat taatgccgac
     1981 accctgcaag aggggctggt tgaggttcgg gatcagatgt tggacgtgtc ctatcagtgc
     2041 ccgcaattgg cccaattaca acaagagctt aagcaggtgc ctccggaatc tttggctttg
     2101 ttttccggct ttaccgacgg gattcaaggg ttgggccttg gggtctatga ctacgcgttt
     2161 gatgaaagcc gtagtgatgg caccttgagt acctacagcc tattgatgag tgtatcggcc
     2221 aaggatccca ccaaggcctt taatgccatc aagatggtga gccctgagtt tgccagtctg
     2281 gatctgaaac cggggcagca ggcggtggac atcaaagacc gggttcctca gctgcaatac
     2341 gccctgcagc ctatcatgct ggagatgagc gaaagtcaat tgatgctgca taccggtgac
     2401 aaaggggcca gggtggctga ggccatgagt gcggagccgc tgacagccaa tggactgatg
     2461 gcggtaacga tggactatca gcaggcgatg ctgccggcaa tggactgggc taaggcgctg
     2521 gaccctgagt tggtgaatca gctgaagtcg atgcaaagct accatctgat catgaaactg
     2581 atgctggatg tggacgatcg tggattggtg ttccattacc agggggattc ggatccaaat
     2641 cggctcaagg ccaagtaacc ttgcctgccc cactctccct gggtggggca atcacttaaa
     2701 gctgtgtcgg acaatgtccc gacccgagcc tctctgtttc tgctaaatgc aaggctgccc
     2761 cggcgttgat gggcgggccg tagcggatct ttagtggtga cttggtcgta gcgtcaggga
     2821 cggcagttgc agccacgggg atttctccta cgctttggag tctgcaccgg aagtgcttcc
     2881 gcgtgcaacg gtggacagga gcgtctgcca cgactcaagg ttaaggagaa cccatgtatt
     2941 ttgaaaatgc agtgcgtcag cacctgcagg ccaatccggc cctgcaacag cgcgccattc
     3001 ataatcgccc cgcggatgtt gccgccgtac gggcactggc tcaagccgcc gtaaatgtgg
     3061 agttattcac cattcccctg tacatgaccg ccatgtactc gttgcagggg atgcatgcca
     3121 ttaccggtga caatgccctg tataaagggc ggctgtggcc cggcatgtcc acctcggcta
     3181 aggtacaaac cgccaaccag cagtgcttta acaccatctt cagcgtgttc attcaggaga
     3241 tgctgcacct gcaattggcg tcgaatatat tcaacgcgtt gactaaaaat gcccctgaaa
     3301 atcagtgcag cccctgcttt accagtccgc tgcttcaaga cccgggcacc ctgggctggc
     3361 attgctatgg cgagaccaag accaccattc cccacatcat caacctgaaa gacaccacgg
     3421 tttaccagag cgtaacggtg tcgctgggcg aggtgaacga caacaccgtg gcgttgtttc
     3481 tggccatcga agagccggcg gatgtactgc aaacgctgat cctggacagc aaacgcggcg
     3541 actatctggt gactaaaggg ccgctgtccg agcaggtgcc gtttgacggc tggaccgccg
     3601 acaataccga gaaagatctg ccgatgtttg gcaccatcgc cgccatgtac gaatgtctgg
     3661 cgctgtatct gaatctggag tacagcgatg gtaccaccct gatagaggcg ttgtataagc
     3721 cggactcgat tcagaacgac ttgtttaata ccgagagtga ggggcattgc agtccggaat
     3781 ttcctcacct caataccgtc atcgatgctg gctcggccgt cgaagccaag gcgcagatcc
     3841 tgaccatgat ggacgccatc accgatcagg gggaagggtc cactctcaag gtgcaggggc
     3901 cacaggtggc ggtacgccct cagggcatgg tgggtgatgc ggtcaagccc aactatcagc
     3961 cggattttaa tgccctgaag aacgactacg tcagctataa cgacgacggc cagaaggtgg
     4021 agtcggcgga tgcccatgcc cgcttctttg gtggggtggt ggatcattac gatcgcttcc
     4081 agcaggtgcg aggcttgctg gagtccggtc aactgaccac ctggtcgcag tggcataacg
     4141 cttccgatca gcccagaagc tggcaggcca gcatgctgga gctggagggg gcggcgccca
     4201 tcgccggcat acccactgcc gaagaggtcg ccggggcgct caatcgcctc aatgccccgg
     4261 acagtcgtga tggcaaccta gagctgttca gccgggttgc cgccggcgcc atcgccggca
     4321 tcaccacggt gctgaatgac tattggagca cgccaaacac ggatttcccg tttccctcca
     4381 tggcgggctc cggggatcgc atctccatct gttgggcggt gtttggccag gcaccggacc
     4441 tgagcctggg ccagtttgag cgccacagcg gtgactctgc acccttgtac catgcctgtc
     4501 aggggctgga ctacggtgac agcgccgagg gcaaccagtg tgcgtctaag gaggtgtttc
     4561 atacctgccg tggctctaac gcctgcaaag gggagggcgg ctgtggcttt gtacagagca
     4621 ccaagggggg cagtggctgt aacgccatgg tggccaagac cggcgacgat gagctgtaca
     4681 cggcgccggg cgacaacttc tgtggcagtt acggtggctg tgccgtgccc atttccgcct
     4741 ctcagcggtt cccgaaatcc ggcaccatgg cgctgtatca gttgtttgcg gataaggact
     4801 cggtgaagct ggagcagacc ctgagttttg acgagggcga ttcggtgtac gccactgcct
     4861 ggaaagccta tgagaaagtg atggccagcg aaggtaagcc ggccggtaac gcgccggagg
     4921 ccagcgatct gcgcctggca tttccaccct caacctagtg ccattgaacg ggggcccggc
     4981 ccccgttgca gggagacgct atgcaacaga taactaccga gctggggttg ggagtggggc
     5041 ttcgtagctg tcacttttcc tggttaatgg cacagcggga ttcggcggcg ctgggcgttg
     5101 actggctgga gatcatcacc gagaacttcc tcgataacta tggctatgcc cgtcacgtgc
     5161 tgctgacgct tagagagcgg ctgccgatgg cgatgcatgg agtgtcgctc tccatcggct
     5221 ccaccgaccc gctcaatgtg gagtacctgt ataaagttaa acggctggcg gatgaactgc
     5281 agccggcctt ggtgtcggat cacttatgct ggaccggact gcaagggatc aacagtcatg
     5341 atctgttgcc gatgccactg acccgggaaa gtctgaatca cgtctgtgtt cgggtagccc
     5401 aggtgcagga gattctggac cggcctctgg tattggagaa ccccagcagc tacctggctt
     5461 tttcggaaaa cgagttccac gagtgggagt ttctcaatga gctgtgcgcc cgctgtggct
     5521 gtgccttgct gttggatgtc aacaacgtct atgtgacctg ctccaatctc ggttgggacg
     5581 ctcaggccta cctggacggc attgacgccg ccaatgtggt gcagtgccac cttgcgggac
     5641 cgaccgactg cggcactcac ctggtggata cccacgatca gccggtgcca acgccggttt
     5701 ggcagctgta tcgacaactg gttcagcgta ccggtccgct gagtacgctg ctggagtggg
     5761 acgatcgtat tccaccgttt cccgagctgg tgagcgaggt ccaactggcc cgtgaggtgc
     5821 tggccggacg gataccggac gtggttccga ccagtgcgac ccagccgctt tccactcctt
     5881 tgcacacaac ggtaacggcc catgaaccca tcgaacctga aacatcagca gagctggttg
     5941 ctacagcgaa ttctgactaa ccgctggagc ggtgacagcc cgctggccta tcccagagcc
     6001 gagtttggcg atcagcaggg aaccttggtg taccagaggg gctatcggct taggttgatc
     6061 gagtgcctga aagcggaatt tcccctgctc aggcgttacc tgggagagga gacctttggc
     6121 ctgtttgcca tgggcttttt ggagtttaag ccctcaagca gctacaccct gtttgatttg
     6181 ggccagagtt ttacccatta cctgaagttg actcagccga aacaagcgaa ttttgagcct
     6241 tggcgctggc gcctgcccgg tcaactggcc caggtggaaa ccgcacaatc tcaggtcgct
     6301 cgggctcaag ggctcgagtc aaatgagccg tcgctgttgc cattgccgct gtggcaattg
     6361 ccgccggtat gggtgccgcc gaccactcgg gtctttgagt gcgatctcga catgatggca
     6421 ctgatggcgc agctatcgcg gcagcaagtg gcgacgccgc ggccgggtcg gcaacaatta
     6481 atgctgtacc ggcatcgcta tcgagtgcat cggcgcccaa tcagcgcgct gcaggcaacg
     6541 gtgttggcgg cgttaaagtc tggccagccc tggtcgcggg cgttggaatt ggctcagtgc
     6601 aactcggcga tgacggaaag cgaacgggtc gccgaagccc tgtcgtggtt gcctcaatgg
     6661 ctcacagagg gggtggtggg gctggataaa ccggccgacc gcgcctgatg cttgctcgtc
     6721 agcggcgcgg gagtttgcag ggcttgggaa cttgagtacc atgaccacag atcttgtctg
     6781 ttggagggct catgcgccat aacctgaatc aattgagagt gttgtcggcg ttgttacagc
     6841 aacccaatct gacccgagtt gcggagcgcc tgcacatgac ccagtcggcg gtcagcaaaa
     6901 ctctgcatca gttgcgacag gatttcgatg accccctgct ggtgcgcgaa ggtcaacgct
     6961 atctgttgac gcctaaggcg caatcgctgc aactgaccct gccgcagcaa ttgcagcaac
     7021 tggatgccct gtatctgccc cagagttttg accctagcct gtgtcagcgc accctggtgt
     7081 tttcttcatc cgattacgtg gctcagcaca tcttcccggc catcgccgcc gaagtggcgc
     7141 gccaggctcc tctggtaaca ctggaatatc gtttgtggga caagggccag ttgtcacaac
     7201 tggcaagtct gccagtggac ctggtgtcca ccatcgtgga atcggtgccg gataatgtgg
     7261 ctcggcggga ccagggggaa gatggcttgg ctgtgctgat gtcggcggat cacccgctgg
     7321 ctgagcaaac tctgacgctg gaacggtatt tgcaatttga gcatttgcga gttagcggtg
     7381 gtggtgacaa ggattcgccg gtggacacgg cgttgcaggc actagggcat cgccgccgct
     7441 gctttgctca ggtgccgttt ttccagtcgg cactggggct gctgatgtcc acgccaacgc
     7501 tgctgaccac gccgctgcac attgctgctc agatgtcgga gcaagcgccg atggtagtga
     7561 agcgattgcc gttcgactgc gcgcgccagc actaccgatt gctgtggcac cgccgcttca
     7621 atgaggatcc ggctcatcgc tggtttcgcg aactggcgtt tccatttttg tgcgaccatc
     7681 tgaaccacta tgtgcagaaa ggcataacta aaacgacttg taggcatgag taactatcgc
     7741 ttttggtaat gttgttatgt gagtaagctt gaaggcaaca ttgatagtga atagagcagt
     7801 aaagcagtaa tgacgttttt aacttggttg cctctggcaa cagtatgcgt actgggcgcc
     7861 ctcagtcctg gccccagcct ggcgctggtg attaataaca cggtgcagcg gggcacggcc
     7921 accggcctgc gaaccgctct gggacacggt attggtgtgg ccctgtatgc attgatcacg
     7981 gccatggggc tggggttgct tatcagccag acgccctggt tgtttgatgg cattaagtac
     8041 gccggtgcgg catttctggt gtacatggcg attaagattt tgctggccaa gcccaatgtc
     8101 gaagggcaga gcaggtcgcg caaaacccgt tttgtcggtt ttggtggtgg tttcatggtg
     8161 gcttttctca accccaagct ggcgatcttc ttcctggcac tgttcagcca atttgtgcgt
     8221 gccgatctca cccttgggga tcaactgctg atgatggcca ccgctggtgg tatcgatgcc
     8281 ctgtggtacg ccgcggtggc gcttgggatc ggccgtaccg gtttactggg ttggctgcag
     8341 cgccacggta tttgggtgga ccgggtgagt gcggtgattt tcttgctgct ggcaacggcg
     8401 gtggtgttac agtaactttt gttaagcacc tgtttgcacg atattagtgg accgattttt
     8461 tcaatctgac tgaacggtat tatcactgtg atccagagca cagttgcgaa agaggtgtct
     8521 tgagccaccc agcacagcgg ttaagctggt gtcaaccgtt gtcggactaa ggagtgatgt
     8581 ccatggatac taatgttaaa tacgctttgg gcgccgttgt tggctctctg ggtaccatct
     8641 gcttcctggc ttccttgatt ttctaagtcg gaccaagcag aaaaaatgcc gcccgatgag
     8701 gcggcatttt tgtgcctgcg atttgttcga atcagggcag aatgatgtgg gggacgaatc
     8761 gggacaggtc ctgggtgatc aggctgtgat cttcccgtac cgagatcccg gcggcttcat
     8821 cgcccaccaa ccaagagccg ataagggcat agtcgtcgcc aaacttaggt aaatcctgaa
     8881 acgcctggta gataacgccc tcttcgccgt agggaccatc actgtcggcg atagattggt
     8941 tgccgtcgag aatgcggaca ttggcgcctt cacgggagta gattggcttt tcaaccaagc
     9001 gggattcgtt agccagatgg cgttcgtcgg caaaataggc cggcaacagg ttagggtggt
     9061 tggggaacag tttccacaac atcggtagca gtgccttgtt ggacagcacc gatttccagc
     9121 ttggctccag ccaccgggtc tgggctttgt cgatgtagtc gccaaactcc tcccgtaaca
     9181 taaattccca tggatacagc ttaaaggctg cgtgcatggg gcggctgtct ccatccacaa
     9241 agccaccctg aggggtgata ccgatggact cgatataggt aaacagcgtt tgcaggccgg
     9301 cttcttcagc gcagtcctgt aggtactgca ccgtgccccg atcctcgtcg gtgtcctgac
     9361 agcaggcgaa gtgcaggggt accggtggcc aactctgttt cagttgagca aagcgggcga
     9421 tcagttgttc ttgaatgctg ttgaactggt cactgccgtc ggccactgtg ccatccttca
     9481 gtcgttcgtc cagccacagc cactgaaaga aagcagactc gtacagagag gtgggggtat
     9541 cggcgttatt ttccagcaac ttagccggac cgctgccatc gtaggccaga tccagtcggg
     9601 cgtacagagc cgggtccttc aggcgccagg agcgggcgat catctcccag tgagcttcgg
     9661 gaatggcgaa tttacgcagt agggcgtcgt cctgaaccac tttgtccacc acctccagac
     9721 acatctggtt gatctcagtg gtggggtctt ccagatcccg ctcaatttga tccagcgtga
     9781 aggcgtagta gcgactttca tcccaatagg gctcgccata catggtatga aagttaaaac
     9841 cgtaggtctc ggcctgctgc tgccagttgg ttctcggggt gataaggtga cgttgcatta
     9901 gccgccccag ccacgactgg agctcttacg agcgctgctg cgggctttgg ccgcttgagc
     9961 cgattttacc tgcgccattt taccgaagcc tccccgttgg gtgacattag tggctttctt
    10021 cggggtgaag ttattggggc tggtacggac aacacggtcg ccactgcgtc cgaccacatc
    10081 accggcaccg gtgaccagct tgccattcag tggtgagcgg gcgtttttgg agctgtatac
    10141 cggggcggtg cggtatttgt tgcgggaacc gctgagcata ttaccgagca tgtaaccgta
    10201 catcatcggc ataaaccagc ctccaccacc gccgttatcg gcgtattgtt cgccgtccgc
    10261 cagagtgttc acatcgccag ccaggtcggt ggcaaaatcg ccgccaccgg tgcactgctc
    10321 ggcaccaaat tcgagttcac aatcggccag cgagttaaag cggggagcgg tctcttccgc
    10381 cagcgcctgg gcctctccaa agacgctttg gcacagttga tcctggccgg gatttacctg
    10441 aatgcactcg gtgacgttgc gatagacctg ggcggtttcc tgcatcggtt ccgggctgca
    10501 gcctgtcagc gttagcgaga cgctgatggc ggcggcggtg ggaacggtca gctgtttctt
    10561 gaatcggggt gacaaaatag agcgactgcg cttcacagga gtctcctagt aactcatgca
    10621 ggccgcattc agcaggccga cactgatgtt gatggcggcc agcacgatgg cggcggcaac
    10681 gttattctgt tcaattttct ctaccagacc cggcagaatg acaaagcgga cggcggtgaa
    10741 ggccagtaac tgggccaaca gcgccacgcc ggcccatagc aaatagtcgg tgaccgatac
    10801 cgagttgctg gcggctgcag ccagagccag ggtgaagcct accagtgctc caccaatgcc
    10861 gatggcagcg gcctgattct ggctttcttt aaccagcccc cactcatcgt aaggggtgat
    10921 ggcggaatag atcaccttga atactgcgat cagggccaga
//
