LOCUS       NZ_CP084530            20531 bp    DNA     circular CON 20-MAY-2024
DEFINITION  Paenibacillus sp. YPG26 chromosome, complete genome.
ACCESSION   NZ_CP084530
VERSION     NZ_CP084530.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus sp. YPG26
  ORGANISM  Paenibacillus sp. YPG26
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 3966665)
  AUTHORS   Ma,K., Chen,W., Yan,S.Q., Lin,X.Q., Liu,Z.Z., Zhang,J.B., Gao,Y. and
            Yang,Y.J.
  TITLE     Genome mining reveals polysaccharide-degrading potential and new
            antimicrobial gene clusters of novel intestinal bacterium
            Paenibacillus jilinensis sp. nov
  JOURNAL   BMC Genomics 23 (1), 380 (2022)
   PUBMED   35590262
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3966665)
  AUTHORS   Ma,K. and Yang,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2021) College of Veterinary Medicine, Jilin
            University, Xi'an Road 5333, Changchun, Jilin 130062, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT v. v5.0.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023704175.1-RS_2024_05_20
            Annotation Date                   :: 05/20/2024 03:35:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,770
            CDSs (total)                      :: 3,645
            Genes (coding)                    :: 3,614
            CDSs (with protein)               :: 3,614
            Genes (RNA)                       :: 125
            rRNAs                             :: 11, 11, 11 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 11, 11 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 17 of 31
            Pseudo Genes (incomplete)         :: 17 of 31
            Pseudo Genes (internal stop)      :: 6 of 31
            Pseudo Genes (multiple problems)  :: 7 of 31
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:27:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2638868
            Orig. end                         :: 2659399
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084530.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Yong-Jun Yang Lab, College
            of Veterinary Medicine, Jilin University, Changchun, China.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20531
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="9"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     cand_cluster    1..20531
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20531
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10531](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10531)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     gene            complement(28..201)
                     /gene="rpmF"
                     /locus_tag="LDO05_RS12375"
                     /old_locus_tag="LDO05_12420"
     CDS             complement(28..201)
                     /GO_component="GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpmF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370634.1"
                     /locus_tag="LDO05_RS12375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12420"
                     /product="50S ribosomal protein L32"
                     /protein_id="WP_026263995.1"
                     /transl_table=11
                     /translation="MAVPQRRTSKTRRDKRRTHFKLAVPGMVKCEQCGELKLAHHVCKV
                     CGTYKAREIIKQ"
     gene            complement(276..791)
                     /locus_tag="LDO05_RS12380"
                     /old_locus_tag="LDO05_12425"
     CDS             complement(276..791)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019638130.1"
                     /locus_tag="LDO05_RS12380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12425"
                     /product="DUF177 domain-containing protein"
                     /protein_id="WP_251375695.1"
                     /transl_table=11
                     /translation="MHFQFRKLALTEGSVEFHEALDVHHVTKDRKDITHVSPLQADLKV
                     SSFGEGEVDVKGRLTVDLDMTCSRCLKPLKKQVGIDFEERLKYSENTENVQDEEDDIRY
                     VAEDDVNLVPFIEEALLLNLPFAAVCKDDCKGLCPTCGTDLNEHDCGCDKEVIDPRLAA
                     LKDFFKQQ"
     gene            1035..2264
                     /locus_tag="LDO05_RS12385"
                     /old_locus_tag="LDO05_12430"
     CDS             1035..2264
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014281037.1"
                     /locus_tag="LDO05_RS12385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12430"
                     /product="nucleotidyltransferase"
                     /protein_id="WP_251375696.1"
                     /transl_table=11
                     /translation="MSIVGIIVEYNPLHHGHVYHFTRARQETGAEAAIAVMSGSFLQRG
                     EPAIVSKWARAEMALHMGADLVLELPTAYAVQPAEWFAYGAVSLLNATGLVTHLVFGSE
                     EGSTDKLHELASLLAEESSGMKRAVAEELASGASYPAAYAAAAERALARGAAEGARGLL
                     MQPNNSLGLHYMIALRRLGSAIKPLTIRREAAGYHDAQPGEGAIASATAVRRLILAEGL
                     PKASPYMPDYAADIMARELREGRGPVTWESLRPQLLHQLLTSPAEQLSQIHEMTEGLEH
                     RIKKLLPDLAEPTVISLLQALKTKRYTHTKLQRLLVHVLLGHNKLSNTREILAGGPGYL
                     RVLGFTEKGRELLRRMKKTASLPILTRPPELSHPQLELDLQASAVYASSFPVPDTNQLF
                     RDYRQPPIRL"
     gene            complement(2251..3282)
                     /locus_tag="LDO05_RS12390"
                     /old_locus_tag="LDO05_12435"
     CDS             complement(2251..3282)
                     /EC_number="3.4.21.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009222958.1"
                     /locus_tag="LDO05_RS12390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12435"
                     /product="SepM family pheromone-processing serine protease"
                     /protein_id="WP_251375697.1"
                     /transl_table=11
                     /translation="MQLKNSRIFKAALYFIVMTVVVYVVVYMPTPYMINQPGAALEIKP
                     MVKVEEGDPEEKGSFMMTTVSVTYANLAMLVTSQFNSEAEIVRKTPEQGGKEYETRQVY
                     YMSDSQSSAMAAAYTKAKLPYRILPEYIFVVSLSKSPAPKGDFAPGDIIRKIDGRRVIR
                     LKELSGMLKTRKPGEVVQVELERGGRKLAGKAELVSLKDPATGGTRPGLGLNIAELRKV
                     KSVDPRKQVEFTKTEVGGPSAGLMFTLEIYNRLTPGDLSKGYRIAGTGTMSADGHVGPI
                     GGVPFKIVAADRKKAEIFFVPEDNYKAAKKKAEDIGTPMKLVPVKTVDDALQYLSSLAP
                     KAG"
     gene            3435..4652
                     /locus_tag="LDO05_RS12395"
                     /old_locus_tag="LDO05_12440"
     CDS             3435..4652
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019292.4"
                     /locus_tag="LDO05_RS12395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12440"
                     /product="nucleoside recognition domain-containing protein"
                     /protein_id="WP_251375698.1"
                     /transl_table=11
                     /translation="MEGTQRQGGRLWVTIILGSSAVLLAASIVISPGAAFEASLQGLTL
                     WWRIVFPGLLPFLVLSQILVAYGLVHAVGITLDPLLRKGLGTPGVAGWVIPLGLIAGFP
                     AAAEASVQLYRGGRITARQAEKLAAAGHFCNPMLIIVVVGTGFLHKPGLGLLLAVVHGI
                     AGIAAGLTLHKVILQSRRDLYQAGPEPIRTGSKAQQIARSIEEARRLDGRSFGKLLGDT
                     VAAAVQTLMMIGGYMLIFAVVIRMLQYYIPGLVPSFFLPGIFEVHLGTYAAGGLYTYSP
                     ALQAALLGAILGFSGLCAYLQVRAILRPAGIGTGGFLITRILHGSYAYVLTLLLWEPLI
                     RLFPGAAPVYGDISPHGKPDYGILQLPSWTQTFSLMGWQFIALLSITAALMLFTVLWRF
                     RYPISR"
     gene            complement(4657..5163)
                     /gene="coaD"
                     /locus_tag="LDO05_RS12400"
                     /old_locus_tag="LDO05_12445"
     CDS             complement(4657..5163)
                     /EC_number="2.7.7.3"
                     /GO_function="GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="coaD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018750823.1"
                     /locus_tag="LDO05_RS12400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12445"
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="WP_251375699.1"
                     /sec_met_domain="CTP_transf_like (E-value: 2e-21, bitscore:
                     74.4, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQTNKNLRIAVYPGSFDPVTMGHMDIIQRAARQFDVLIVAVLNN
                     SSKNPLFTMEERKELLQQATKDLPNVEVDSFNDLLVNYMVQKKAHVIVKGVRSVTDFEY
                     EMQMASINHKLNSEVETIFMMTNPKYSYLSSSVVKEIARFQGEVVDLVLPEVEEALRQK
                     FTSNR"
     gene            complement(5150..5755)
                     /gene="rsmD"
                     /locus_tag="LDO05_RS12405"
                     /old_locus_tag="LDO05_12450"
     CDS             complement(5150..5755)
                     /EC_number="2.1.1.171"
                     /GO_function="GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /gene="rsmD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689241.1"
                     /locus_tag="LDO05_RS12405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12450"
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="WP_251375700.1"
                     /transl_table=11
                     /translation="MRVISGTAKGRPLKAVPGTGTRPTTDKVKEAIFSMIGPYFDGGRA
                     LDLFAGTGGLGIEALSRGMERAVFVDLEYKSLEVVKANLRATGLEDRAEVYKNDAERAL
                     KALARRETSFDLVFLDPPYRLKHGDKLMNKMDELALLEDKAILVLEYESSYEYPERVGN
                     FTRVRLAEYGETVVSVYRYEPGGDAEEAGQEEEQHESN"
     gene            complement(5854..6045)
                     /locus_tag="LDO05_RS12410"
                     /old_locus_tag="LDO05_12455"
     CDS             complement(5854..6045)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006288170.1"
                     /locus_tag="LDO05_RS12410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12455"
                     /product="hypothetical protein"
                     /protein_id="WP_251375701.1"
                     /transl_table=11
                     /translation="MGEEKPDEELMGKRKSSPRLSTTFGDVDIFIVSAFAAFIPEVSKK
                     GKDRLIRVLLFNQGRADN"
     gene            complement(6246..6911)
                     /locus_tag="LDO05_RS12415"
                     /old_locus_tag="LDO05_12460"
     CDS             complement(6246..6911)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007130229.1"
                     /locus_tag="LDO05_RS12415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12460"
                     /product="DUF2642 domain-containing protein"
                     /protein_id="WP_251375702.1"
                     /transl_table=11
                     /translation="MQVFKKWLNQTVELELSGCNERIIGRLIDIGSDILVLFSGSKFIY
                     IPIHHLQNAYLSLDDLQLNDSNLSPSLEQEQISYRKMLMNSRGMFTAVSIGNKRSIHGY
                     LTGIMNDYFVFYSPIYGSVYVSINHVKYLVPYPPNQTPFNLSQDHFPVQPAALPISRTL
                     DQQIKKLEGELIVVNLGEKPCHAGLLRALDNNMLEMIDASGVTSLIHGDHIMTIHLPK"
     misc_feature    6887..6902
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(6925..8268)
                     /locus_tag="LDO05_RS12420"
                     /old_locus_tag="LDO05_12465"
     CDS             complement(6925..8268)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013055776.1"
                     /locus_tag="LDO05_RS12420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12465"
                     /product="arsenic transporter"
                     /protein_id="WP_251375703.1"
                     /transl_table=11
                     /translation="MPDYQQWLAFGVFVFTIILLMWRPGRMNESIPTSLGALILVLAGV
                     VSYRHILEVFGIVSGAAVTILSTIVMSIILESIGFFRWVAFNLVERARGSGVKLFWLIL
                     LLCFLMTLFFNNDGSILITTPIIIQIGNILELKPKQKIPYLLSGALIATVSSAPIGVSN
                     LANLIALRIVGLDLNQYTAMMFVPSMIGILCISALLYLYFQRDIPREISKTPIRYSLQS
                     GRHPLLYNHKIDSQVDWWLFRACIGIVVFIRAGFFLAEDIGIPIELVALIGVVLMIVVR
                     WYRTKKGLRDVVTKTPWHILLFAFSIYIIVNSLHRAGMTEWLITLLQPFADKSEAGLIA
                     ASGLMLTLLSNLVNNLPSVMIGTFAVTDMGLEQQSLQLAYLANIIGSDIGAVLTPVGTL
                     ATLLWMYILKNHHIPITWKQYMKVTLIVIPIGLIVSLMSLFVWTQFLL"
     gene            8770..8967
                     /locus_tag="LDO05_RS12425"
                     /old_locus_tag="LDO05_12470"
     CDS             8770..8967
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LDO05_RS12425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LDO05_12470"
                     /product="hypothetical protein"
                     /protein_id="WP_251375704.1"
                     /transl_table=11
                     /translation="MDHSFHKAVDKYRKQSKEARKHFKHVKDKALGEGLVALSKSLNQI
                     NTKLNVINKKLDRIKKGHRY"
     gene            complement(9155..9268)
                     /locus_tag="LDO05_RS12430"
                     /old_locus_tag="LDO05_12475"
     CDS             complement(9155..9268)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019638816.1"
                     /locus_tag="LDO05_RS12430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12475"
                     /product="YjcZ family sporulation protein"
                     /protein_id="WP_251375705.1"
                     /transl_table=11
                     /translation="MSEVRGGGYGGGGVFTSTGAILVLFILLVIISRSILY"
     misc_feature    complement(9345..9359)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.21"
                     /tool="antismash"
     gene            complement(9375..9656)
                     /locus_tag="LDO05_RS12435"
                     /old_locus_tag="LDO05_12480"
     CDS             complement(9375..9656)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007132840.1"
                     /locus_tag="LDO05_RS12435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12480"
                     /product="hypothetical protein"
                     /protein_id="WP_251375706.1"
                     /transl_table=11
                     /translation="MLPDFERKLLRILYNYSLKYRRIPDLREIQRLTGRHRTEDIKEGI
                     LRLEKEKYILWEDRDDVGTIRILEGWDREQSGFSRSDTSSSTEYWTKY"
     misc_feature    complement(9729..9742)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 22.9"
                     /tool="antismash"
     misc_feature    9729..9743
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.51"
                     /tool="antismash"
     gene            complement(9873..10004)
                     /locus_tag="LDO05_RS18855"
     CDS             complement(9873..10004)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LDO05_RS18855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_276575512.1"
                     /transl_table=11
                     /translation="MKKQLARSISDFLYKSAKKSSISPKSFIGAKPLPRELQEIKSK"
     gene            complement(10001..10531)
                     /locus_tag="LDO05_RS12440"
                     /old_locus_tag="LDO05_12485"
     CDS             complement(10001..10531)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /locus_tag="LDO05_RS12440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12485"
                     /product="accessory gene regulator B family protein"
                     /protein_id="WP_251375707.1"
                     /sec_met_domain="AgrB (E-value: 1e-18, bitscore: 65.1,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGLEALSRHLSSKIKESDPEGPVSLEILEYELGIRLNFIATLLM
                     TVLAGWITGNLWEACLAMVSFLVVRRFSGGVHMKSLTLCALVSASIFVSIPFIVLDPEQ
                     IRLFTLISAAVFLIYSPNILEELNPPPLTPYMKAISVALVLSNYIFQSSAIALACAVQA
                     FLILPFWKGGESR"
     gene            complement(10476..11174)
                     /locus_tag="LDO05_RS12445"
                     /old_locus_tag="LDO05_12490"
     CDS             complement(10476..11174)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LDO05_RS12445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LDO05_12490"
                     /product="hypothetical protein"
                     /protein_id="WP_251375708.1"
                     /transl_table=11
                     /translation="MSSSYVYIGLGIFDALAMFALMISLYRLPLWSHRYKVTAFAVFIA
                     LFSFVMRLLIEIPQLDLPIQYLFFLIFIKYVYRLKFSHSSFVAGAGITAYAVLQLTISY
                     VYNLVGMIYQSDLLKTEGAVYLIQISSILAAYGISIFLKYFRLGFSFIQIPQDGRPSPQ
                     KEQTSLLIASILSTITIFLISFFLYNVDFPGLIIMTFSTFSISYYFSQRSDYEGVRSII
                     EASLEQDKGK"
     gene            complement(11435..12340)
                     /locus_tag="LDO05_RS12450"
                     /old_locus_tag="LDO05_12495"
     CDS             complement(11435..12340)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018759617.1"
                     /locus_tag="LDO05_RS12450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12495"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_251375709.1"
                     /transl_table=11
                     /translation="MQAANKTFVAVWISLISNLFLTGIKIFVGVLFKSQVLIADGIHNA
                     GDVVASFAALTSTRISKKPADEDHPYGHGKAEVLASAVVALILALAAILMIVKSIESFF
                     APAEEASIIALSAALISLIWKQVLYVYCIRIGRAENSKSLMATAYDHLADVYASAAACA
                     GIGLALLGDYYDIPFTKYGDPIAGLVVSYFVIKLAYKMGRESVDILMEKNIDQEKLDSI
                     HQIVNQVEYVRRIDRIRARELGNYIIVDVRVSIPSELTVQQGHDVSKEIRNSIKSGVSY
                     VEEVLVHINPWYHGDTSEEK"
     gene            complement(12613..13431)
                     /locus_tag="LDO05_RS12455"
                     /old_locus_tag="LDO05_12500"
     CDS             complement(12613..13431)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013357.4"
                     /locus_tag="LDO05_RS12455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12500"
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="WP_251375710.1"
                     /transl_table=11
                     /translation="MQTRSGNHAQGIDVSHWQGAIDWRKVRAAGKSFVFIKATESSRYT
                     DNQFFNNLKGAKSAGLLVGAYHFTRAAKPADVKAEVDHFLSVINQAGGLDTFELPFVLD
                     IETKEAGTRANVTATVRAWVDEFKRRTGRTPLLYTYPSFIEGYLDSSLADVPLWYAYYS
                     NVPPVNKSGWKSWEFLQYTSEGTVPGIGGNVDLNEYRGSEAELMAVYKKGNNGSKPPGH
                     NPEVPAWKESGRQWLIDHAGISSDWKAEDPVDIGTLGAILAKFTSRTKNS"
     gene            13656..14333
                     /locus_tag="LDO05_RS12460"
                     /old_locus_tag="LDO05_12505"
     CDS             13656..14333
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017689262.1"
                     /locus_tag="LDO05_RS12460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12505"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_346657574.1"
                     /transl_table=11
                     /translation="MMSKFILFSALWWLVGNPFLAIIILLAIIYVLDRQFVGVFPSVTR
                     PFRRMRDISLLRQQLALNHHDISAKRDLARLLLERKKYSEAYSLLQEMESSSRESAEYW
                     DDLGTAALGLGQVEEAEAHMLRALELNERVRYGQPFLKLAAVYQNRNAEKSIYYAEKFS
                     LIHSSSCEAYFLLGNVYQSLNRKDEARRAYTESISIYRSLPKYKKRHERKWALRSWLKR
                     QQV"
     gene            complement(14501..17674)
                     /locus_tag="LDO05_RS12465"
                     /old_locus_tag="LDO05_12510"
     CDS             complement(14501..17674)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015736775.1"
                     /locus_tag="LDO05_RS12465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12510"
                     /product="MMPL family transporter"
                     /protein_id="WP_251375711.1"
                     /transl_table=11
                     /translation="MRFILKARWWMILFWIAAAVGLMLTAPSMADLVRQKGNLSVPPGY
                     ASSEASDLMKEISAMKGGGKETQIALVFHEDNPLNQEAKDSIKSGIQKLNDAKAKIGIV
                     SITDPFSTPDAADKMISKDGKTILTSLSVEMDGRPLKDTVKDIRSTLDSVPVKHYLTGQ
                     EQINEDTIASSESGLKKSEYITVVFILLILFISFRSFVAPFIPLLTVGISYVVAQSVVA
                     FLVDSFDFPLSTFTQIFMVAIMFGIGTDYCILLISRFKEELQHTDDKWEAIIATYRTAG
                     KTVFFSGLAVLVGFAAIGLSEFILYKSAAAVAVGVAVMLLALLTVVPFFMAVLGTKIFW
                     PAKGSLEHKENKFWGMFGAFSLKRPWAALLLVAVFTLPFVFTYSGKVSFNSMEEIGDNY
                     ESVKAFNIISDSFEPGESLPTSIVIKNNERMDSAEYMTLAEKISREVKSVDGVASVRGL
                     SRPTGDEVKDFKLTEQVKTVGEGLGKGNEGLNTIKDGLAKASNSLSENEPKLKQAADST
                     GKLAEGTAKLKDGISQLNNGLTAIEKGIRSGSDGAGQLKQGLQQAKKSAQQLAAAQQQL
                     LKSYQQIGQGLGSINGGLSRVNEQLTGAAQGLNGLSGKFSSLESKYPELASDPDYLTIR
                     GTVTETGKGMTQLAAGLKQLQAPLNQAAGGLKQANEGLAKIAGGQSALAGGFDQLISGI
                     SQLESGLDQAASGQGQIIDRIPSVVSGLSQIENGQKQVQNGFTQFSGQISKLTDGLSQS
                     ADGIAKVSGGLDSAKDYLNQVGTADSGLGGFYVPDEALDNKDITQLFDTYLSADRKIMT
                     LDVVFSENPYGTEAISQVDQIKAAVDRAVQGTKLAEAEIGFGGVSSTFNDLRSISNEDY
                     TRTVILMLAGIFIILVLLLRSVIMPIYLIASLVLTFYTSMGVTELIFVKIMGMSGISWA
                     TPFFGFVILVALGIDYSIFLMDRFNENKSWKVGDAILHAMRNMGTVILSAAVILGGTFA
                     SMYPSGVMSMMQIATVVLTGLALYSLVILPFFIPVMVKLFGSANWWPFSTRDEADHVKS
                     SKVEHTKMS"
     gene            complement(17675..18121)
                     /locus_tag="LDO05_RS12470"
                     /old_locus_tag="LDO05_12515"
     CDS             complement(17675..18121)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019419282.1"
                     /locus_tag="LDO05_RS12470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12515"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_251375712.1"
                     /transl_table=11
                     /translation="MEQQSKELIERYVTASATVTKRLSSEIAKIVQDDMTVDQYQTLYY
                     IKTQHECTSTELADAFCVGKSSITAIITRLVDRGLVERTRDKEDRRLVYLSLTELGHEI
                     SSKADEKVQEVVAKYLVHFNQEEIESFITSFEKLARLFEEGSKE"
     gene            complement(18332..18769)
                     /locus_tag="LDO05_RS12475"
                     /old_locus_tag="LDO05_12520"
     CDS             complement(18332..18769)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015736385.1"
                     /locus_tag="LDO05_RS12475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12520"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_251375713.1"
                     /transl_table=11
                     /translation="MLVNVKNQVESPDISRILEYAVYSDEDLLAEAIKRYQEDREAQLY
                     ALKHEEELIGLIGYKMEDQNALVINHLAISPEHRNQGYGRGIILEVLYQEKPDRIIAET
                     DEEGVDFYRNIGFVIETSSKLPNGVERFRCVYEAELHEQEE"
     gene            18948..19283
                     /locus_tag="LDO05_RS12480"
                     /old_locus_tag="LDO05_12525"
     CDS             18948..19283
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LDO05_RS12480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LDO05_12525"
                     /product="hypothetical protein"
                     /protein_id="WP_251375714.1"
                     /transl_table=11
                     /translation="MMTQAAVKLSQRIDDYLDLLNYAKQIGDGEWHTHILLTLETLYNT
                     SEDELHKEMEEELWRQFDQINARMMDLFIQIRRSADDTTKQMLLEQMWTLKLERVTLSQ
                     QIKSHSK"
     gene            complement(19447..19665)
                     /locus_tag="LDO05_RS12485"
                     /old_locus_tag="LDO05_12530"
     CDS             complement(19447..19665)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009674360.1"
                     /locus_tag="LDO05_RS12485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_12530"
                     /product="hypothetical protein"
                     /protein_id="WP_251375715.1"
                     /transl_table=11
                     /translation="MDKMCMQMMMNMCMEDMMSKMNSMKMMMECCSNMDMMNMDMDMGM
                     MMKKMQDCDEMMTMMMKMMREMKQTSV"
     misc_feature    19745..19754
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
ORIGIN
        1 atgtaggtac tactttgatt tcattcatta ttgcttgata atttctcttg ctttgtatgt
       61 gccgcatact ttgcatacgt ggtgagcaag cttcaattct ccgcattgtt cacattttac
      121 catgcccggc acagccaatt tgaaatgagt gcgacgtttg tcacgacgcg ttttggacgt
      181 tctccgttga ggtactgcca tggttcccac ctccttattc aagtcaacct ggttccattg
      241 cttagtttag acgaccgtta ggtgtcagac tgttattatt gttgtttaaa aaagtccttc
      301 agcgccgcga gacgcgggtc gatgacttct ttatcacagc cgcaatcatg ttcgttcaaa
      361 tcggttccac aagtagggca cagacctttg cagtcatctt tgcagacggc agcaaatggg
      421 agattcagaa gcaaggcttc ctctatgaaa ggaaccagat tcacgtcatc ctctgcaacg
      481 tagcggatat cgtcttcttc gtcctgaaca ttctctgtat tctcactgta cttcaaccgt
      541 tcctcgaaat cgataccgac ttgcttcttc aaaggcttca ggcagcggga gcacgtcatg
      601 tccagatcca ccgttaatct accctttaca tcaacttctc cttcaccaaa ggaacttacc
      661 ttcagatcag cttgaagcgg actcacgtga gtaatatcct tacggtcctt ggttacatga
      721 tgaacatcca gtgcttcgtg gaattccaca gagccttcgg ttaatgccaa tttgcgaaat
      781 tgaaagtgca tgatcatcac tccaaacaaa caaaatttat tataccgatt tttagagagt
      841 tttgtcaata acttaaacgt actgttacct ttagtatacg gtatctcacg gcatcctacc
      901 cataacaaat tgcaaatctg cttgcgcatt cctaaggaca ggtccgtaaa ttatagcatg
      961 tttattcggt aaatgatgca gttcatgata ttatttctct ataaaatcat gaatgcatgc
     1021 aaggaggccc cgatttgagc atcgtcggca taatcgttga atataatccg cttcaccatg
     1081 ggcatgtcta ccatttcacc cgggccagac aggagacggg tgccgaagcc gccattgccg
     1141 tgatgagcgg cagcttcctt cagcggggcg agccggccat cgtctcgaaa tgggcccggg
     1201 ccgaaatggc gctgcacatg ggcgccgacc ttgtgcttga gctgcccacc gcctatgccg
     1261 tgcagccggc ggagtggttc gcgtatgggg ccgtgtcgct gctgaacgcg actggtctcg
     1321 tgacgcatct ggtgttcggc agcgaggaag gaagcacgga caagctgcac gagctggcct
     1381 cgctgctcgc cgaggagagc agcggcatga agcgcgccgt ggcggaggaa ctcgcctcgg
     1441 gcgcgagcta ccccgccgcc tatgccgcgg cggcggagcg ggcccttgcg cgcggcgcag
     1501 ccgaaggcgc gcgcgggctc ttgatgcagc ccaacaactc gcttgggctg cactacatga
     1561 tcgcgctgcg ccggctgggc agcgcgatca agcccttgac catccggcgc gaagcggccg
     1621 gatatcacga tgcgcagcct ggcgagggcg ccatcgccag cgccacggcg gtccggcggc
     1681 tgatactggc tgagggactg ccgaaggcga gtccctacat gcctgattat gccgccgaca
     1741 tcatggcccg cgagctgcgc gaaggccgcg ggcccgtgac ctgggaatcg ctccgcccgc
     1801 agctgctgca tcagctgctg accagtcctg cggagcagct ctcccagatc catgagatga
     1861 cggaggggct ggagcaccgc atcaagaagc tgctgcccga tctagcggag cccacagtga
     1921 taagcctcct tcaggccttg aagaccaaac gttacaccca taccaagctt cagcgcctgc
     1981 ttgtccatgt gcttcttggc cataataagc tgtccaacac ccgggagatt ctcgccggag
     2041 gcccgggcta tctgcgtgtg cttggcttta cagagaaagg cagagagctg ctcagacgca
     2101 tgaaaaagac ggcctcgctg ccgatcctga cgaggccgcc cgaattgtca catccccagc
     2161 ttgagcttga cctacaagct tcggctgtct atgcgagctc cttccctgtc ccggatacga
     2221 accagctctt ccgggattat cgccagccgc ctatccggct ttaggcgcaa gcgagcttag
     2281 atattgaagc gcgtcgtcca cggtcttgac gggcaccaac ttcatgggag tgccgatgtc
     2341 ctcggctttc ttcttcgccg ctttataatt atcctcaggc acaaagaaaa tctccgcctt
     2401 cttccggtcc gccgccacaa ttttgaaggg tacgccgcca attgggccca catggccatc
     2461 ggcggacatc gtacctgttc cagcgatccg gtacccttta ctgaggtccc ctggtgtcag
     2521 ccggttgtag atctccagag tgaacatcaa gccggcggaa ggcccgccga cctccgtctt
     2581 ggtgaactca acctgcttgc gcggatccac cgatttcacc tttctaagct cagctatatt
     2641 cagtccaaga ccgggccgcg tcccccctgt ggcagggtcc ttcaagctga caagctcagc
     2701 cttgccggcg agctttctac cgccccgttc aagctctact tgaacaacct ctcccggctt
     2761 cctggtttta agcattccgc tcagttcttt caaccggata acccgtctcc cgtctatctt
     2821 gcgaatgata tctccaggag caaagtctcc cttgggagca ggtgacttgg atagagagac
     2881 gacaaagata tattcgggta ggatcctata gggcagcttg gccttggtat aggctgctgc
     2941 catcgcgctg gactgcgaat cgctcatata gtacacctgc cgggtttcgt attctttccc
     3001 accctgttcg ggcgtcttgc ggacaatctc tgcctcggag ttgaactggg acgtaaccag
     3061 catggccagg ttcgcatatg tcacagacac cgtggtcatc atgaaggatc ccttctcctc
     3121 cggatctccc tcctccactt taaccatcgg cttgatctcc agggccgcac ccggctgatt
     3181 aatcatatag ggtgtaggca tatacaccac aacatacaca acaactgtca tcacgatgaa
     3241 atataatgcc gctttgaaga ttcttgaatt cttgagctgc accggtgtct ccctctccct
     3301 taatctgcag tatggacaaa ggctggtctg atctgtgtcc gccatgcata aatttgtact
     3361 agccttaaga gcatcaggaa ctctcattgc aggcagttcc atcatcattt atttcataat
     3421 gaggtgagtc attcatggag ggaacacagc ggcaaggcgg acggctgtgg gtaactatca
     3481 ttctaggcag cagcgctgta ttgcttgcag ccagcattgt gatttcacct ggagccgcat
     3541 ttgaagcttc gcttcagggc ctgacactgt ggtggagaat tgtattcccg ggtcttttgc
     3601 cattcctggt tctgtcccaa atcctggttg cttatggatt agttcatgct gtgggtataa
     3661 cactcgatcc cctgcttcgc aaaggactcg ggacacccgg tgttgccggc tgggtaatcc
     3721 ctctcggact tattgccggc ttccccgcgg ccgccgaggc atctgttcag ttgtacagag
     3781 ggggcagaat tacagccagg caggcggaaa agctagctgc tgccggacat ttctgcaatc
     3841 ctatgctgat tatagtcgtt gtcggcaccg gctttctcca taagccgggg cttggcctgc
     3901 ttctggccgt ggtccatgga attgccggca tagctgcggg ccttactctt cataaggtca
     3961 ttcttcagag ccgcagagac ttataccagg cggggcctga acccatacgc acaggctcaa
     4021 aagcacagca aattgcccgc agcattgagg aggcccgccg gttggacggg cgcagcttcg
     4081 gcaagctgct aggtgatact gtggctgctg cggttcagac gttaatgatg ataggcgggt
     4141 atatgctaat ctttgcagta gttattcgta tgcttcagta ctatatacca ggactcgttc
     4201 cttccttctt ccttccagga atcttcgaag ttcatcttgg cacttatgct gcaggaggcc
     4261 tctacaccta ttctccagca ctgcaagctg cgcttctggg tgcgatttta gggttcagcg
     4321 ggctgtgcgc ctatctgcag gttcgtgcca ttctcaggcc cgcagggatt ggtacaggcg
     4381 ggttcctgat cacccggatt ctgcacggaa gttatgctta tgtactcaca ctcctgctct
     4441 gggaaccgct gatcaggctt tttccaggag ccgcccctgt ctatggggat atatcccctc
     4501 atggcaagcc ggattacggc atccttcagc ttccgagctg gacacagacc ttctccctga
     4561 tgggatggca gttcatcgca ctcttgtcta tcacagccgc cctgatgctg ttcaccgttc
     4621 tttggcgctt tcgttatccc atatcccgat agagatttat ctgttcgaag tgaacttctg
     4681 tctcagcgct tcttcaacct cgggaagtac cagatctaca acctctcctt ggaaccgggc
     4741 aatttctttt accacgctgg agctcaaata gctgtatttc gggttcgtca tcataaatat
     4801 ggtctccact tcactgttca gcttgtgatt gatggaggcc atttgcattt catattcaaa
     4861 gtcagtcacg gaacgtacgc ctttcacaat aacgtgagcc ttcttctgca ccatatagtt
     4921 cacaagaaga tcgttgaagc tgtccacttc gacattaggc agatccttcg tcgcctgctg
     4981 aagcagctct tttctctctt ccatggtaaa aagcggattt ttactcgaat tgttaaggac
     5041 ggctacaatc aagacatcaa attgcctggc agcacgctgg ataatatcca tatgtcccat
     5101 ggtgacaggg tcaaagcttc ccggatacac cgcaattctt agattcttgt tagtttgact
     5161 catgctgttc ttcctcctgt ccggcctctt cagcatctcc gcccggctca tatctatata
     5221 cagagactac tgtctcgccg tattccgcta ggcgtacgcg tgtgaaattg ccaaccctct
     5281 ccggatactc ataggaagat tcatactcca gaacaaggat agccttgtcc tccagaagag
     5341 ccaactcgtc catcttgttc atcagcttgt ccccatgctt gaggcggtat ggagggtcca
     5401 gaaatacgag gtcaaacgaa gtctcgcgtc tcgccagtgc cttcaaagcc cgctctgcat
     5461 cattcttgta cacctcggct cgatcttcca gtcctgttgc tctgagattg gctttaacaa
     5521 cttccagact tttgtattca agatccacaa atactgcccg ctccattccc cggcttaacg
     5581 cttctatccc gagtcctccg gttcctgcga acaggtcgag cgctctgccg ccatcgaaat
     5641 aaggcccaat catactgaaa atagcctctt tcaccttatc tgtagtcggt cttgtgccgg
     5701 taccaggcac ggctttaagc ggcctgccct tggcagttcc tgaaattaca cgcaattcgt
     5761 gtcacaccct atcctcgtca catccgtgtc gcttttttta tgacgatatc gtaccatact
     5821 cctacctgaa ttgaaaaact catatatcac taattagtta tccgcccgtc cctggttgaa
     5881 caataacacg cgaattaatc gatctttccc tttttttgag acttcaggta taaaagcggc
     5941 aaaggcggac acaataaaga tatcgacatc accaaatgtc gtagacaacc gcggagaaga
     6001 cttacgtttc cccataagct cttcgtccgg tttctcctct cccatgatgg gcgtcccgcg
     6061 aggggcgccc ggacaaaagc ccttgtatcg tgcaattgta cgagggtttt tgtccttttt
     6121 tttgtggatt gatgaccaaa ttcagctgta ctaacaaaaa caaccggcaa ttcttcactt
     6181 atcatataaa aaccactcct cagagtggtc aagaacatat tcacatatcc acatcagtgc
     6241 gcatttcatt taggcagatg gatggtcata atatgatcgc catgaataag actagtcacc
     6301 ccactggcat cgatcatttc aagcatatta ttatctagag ctcttaggag tcctgcatga
     6361 caaggcttct cgccaagatt cacaacaatg agttcacctt ctaatttctt gatttgctgg
     6421 tctaaagttc tggatatagg tagtgcggcc ggctgaacag ggaaatgatc ttgacttaaa
     6481 ttaaaggggg tctgattggg agggtaagga accaagtatt taacatgatt aatagataca
     6541 tatacacttc cgtatattgg cgagtaaaaa acaaaataat cgttcatgat accggtcaaa
     6601 tatccgtgta tggagcgttt attgccaatg gagaccgcag tgaacattcc tctggaattc
     6661 ataagcattt ttcgatatga aatttgttcc tgctccaacg aagggctgag gttcgaatca
     6721 ttcaactgaa gatcatccaa cgacagatac gcattttgca aatggtgtat agggatataa
     6781 atgaattttg atcccgaaaa taacactagt atgtcgcttc caatatcaat taatctgccg
     6841 atgatacgtt cgttacatcc agacaactca agctcaacag tttgatttaa ccattttttg
     6901 aagacctgca ttctcctcct cctctcaaag caggaattgt gtccatacaa ataaggacat
     6961 cagactaaca atcaaaccga taggtatcac gattagagtt actttcatat actgtttcca
     7021 cgttatggga atatgatgat ttttaagaat atacatccaa agtaatgtgg caagagtacc
     7081 tacaggtgtt aacactgctc ctatatcact tcctatgata ttagccaaat acgcgagctg
     7141 aagagactgt tgttccagcc ccatatccgt cacggcaaaa gtaccaatca taactgacgg
     7201 aagattgtta accagattcg agagaagcgt cagcatcaat cccgaagcgg ctattaaacc
     7261 agcttcactc ttatcggcaa aaggttgcaa taaagttatg agccattctg tcatccctgc
     7321 acggtgaaga ctattgacga tgatataaat gctgaaggcg aacaacagaa tatgccaagg
     7381 tgtttttgtc acaacatcac gaaggccctt cttcgtccga taccatctaa ccacgatcat
     7441 gagtactacc ccaattaatg caacgagctc tatagggata ccgatatcct cggcaagaaa
     7501 aaatcccgct cgaataaaaa caacgatacc tatacaagct ctgaacagcc accagtctac
     7561 ttgactatca atcttatggt tataaagaag cgggtgtctc cctgactgta atgaatatct
     7621 gatcggagtt ttgctgattt cacgggggat atccctttga aaatagagat ataagagagc
     7681 agaaatacat aagattccaa tcatcgaagg gacaaacatc atggcggtat attggtttag
     7741 atccagtcca acaatgcgaa gtgcaattag atttgccaga ttgcttactc ctataggcgc
     7801 gcttgatacc gtagctatca atgctccaga gagcaaatag gggatttttt gctttggttt
     7861 caactctaag atgttaccga tctgaataat aataggtgta gttatgagta tacttccgtc
     7921 attattgaag aaaagagtca taagaaagca aaggagaagt atcagccaga agagctttac
     7981 accagagcct cttgcccgct cgaccagatt aaaagccacc cagcgaaaga acccgatact
     8041 ttcaagtatt atggacataa caatggttga aaggattgta accgcggctc ctgatacgat
     8101 tccgaacacc tcgagaatat gcctgtaact tactacgcca gccaagacaa gtatgagtgc
     8161 ccccagtgaa gtggggatcg attcattcat tctcccggga cgccacatga gtagaataat
     8221 ggtgaataca aaaactccga atgcgagcca ctgctgatag tccggcatta ttgcggttca
     8281 cctcccaagg ggagaatctc agatgaagat gctagttttt ggggtgcagc ctttacggtt
     8341 tttgtcggga gaataagcca atacagcggc aggcctagaa gaatgcagta tgcgtagaga
     8401 tacatttcct cttcctccct tcatacggtt ttcgaagtaa ttctttccct cctaaataat
     8461 taagatcacc tccgtttttg atagagatag ataagcatga gcttaacttt gccggagttt
     8521 attcaagctt cctccacgct tgtcattcat gtccacctct aatgtattca tatgtgtcag
     8581 gggtgagaaa ggaactagcc aaatatgctg attactaaca aaaccctcga atatctagta
     8641 tccatattca aggttggtgt tatgtatttt gagaatattt tttttgatgt ggttttcgtc
     8701 catacgattt tccggccatg agcatctatt acattgtaca attacaaatc atgaagggag
     8761 atcaggtata tggatcattc ttttcacaaa gcagtagaca aatacagaaa gcaatcaaaa
     8821 gaggcacgga agcattttaa gcatgttaag gataaagctt taggtgaagg cctggtagca
     8881 ttaagcaaaa gtctaaatca gatcaataca aagttaaatg taattaataa aaaattagac
     8941 agaataaaaa aaggtcaccg ctattaatta ccttttatta gttaaattct ctgcgaagct
     9001 gttaatgcag cttctttttt tacttttgtt ctaaccctat tacaccctaa ccgggtcttc
     9061 ttcagattaa tacacgcagc acaaaattcc cgccagggca acaagacctt ggcgggaatt
     9121 cgcgtcaaat cactcaggat tcagatattc ttccttagta caggatagaa cgggagataa
     9181 taacgagcag aatgaacagt accagaattg cgcctgtgga tgtgaacact ccgccaccac
     9241 cgtagccgcc gcctcttact tcactcattt gcgaaaacct ccttgtattt aagatacatt
     9301 ggtattgtat tcgcggagtc gctcggtgga ttggacaccc acccaattgt cagcaaattg
     9361 atcgcttacg tctcttaata tttcgtccaa tactctgtac tgctgcttgt gtcactccgg
     9421 gagaatcccg attgctcgcg gtcccagccc tccagaatcc ggatggttcc aacatcatcc
     9481 cggtcctccc acaatatgta tttctccttc tcaagccgaa ggatcccttc cttaatatcc
     9541 tcagtacgat gtctgcccgt caggcgctga atctcccgaa gatccgggat gcgccgatac
     9601 ttcaaagagt aattatacag aattcgcagc agcttgcgct cgaaatccgg aagcatacaa
     9661 ggtccctcct tctcagctta ccaacctata gaattaccat tcccgaacca gtcttatgtc
     9721 attatacagg aacatatgtt ctgttatcaa gtatgaagaa aacccatgtc ttcacatggg
     9781 ctttctatta gacttatatc tggattgtcc tgactgacta agtatgtggt tcactgcttg
     9841 tctggaagat caaagctgta agtaatagga tattacttgg acttaatttc ttgtaattct
     9901 ctagggagcg gcttagctcc gataaaactc ttaggagaaa tggaggattt cttcgcactt
     9961 ttatacaaaa aatcagagat actgcgggct aactgcttct tcatcttgac tcacctcctt
    10021 tccagaaagg aagtatgaga aaagcttgca cagcacaggc gagagctatg gctgaagact
    10081 gaaatatgta attagataga accaaagcta ccgagattgc tttcatgtaa ggtgtgagcg
    10141 gcggcggatt caattcctcc agaatgttag gggagtaaat caagaatacg gctgcagata
    10201 taagtgtgaa taaccgtatt tgctccgggt ccagcacgat gaaaggaata cttacaaaaa
    10261 tggaagccga tactagagca caaagtgtta gtgacttcat atgcacgccg cccgagaacc
    10321 gtcttaccac caggaaggag accatggcca ggcaggcctc ccataagttc ccggttatcc
    10381 atccagccag tacagtcata agcagtgtag ctataaaatt cagccttatt ccgagctcat
    10441 attccagaat ttcaaggctg accggtccct ctggatcact ttcctttatc ttgctcgaga
    10501 gatgcctcga taatgcttct aaccccttca tagtcgctcc tttgagagaa gtaataagaa
    10561 atgctgaagg ttgagaatgt catgatgata agacccggaa agtctacgtt gtacagaaaa
    10621 aagctgatca gaaaaatagt aatggtcgaa agaatggagg caattagcaa ggatgtctgc
    10681 tctttctgag gagaagggcg tccgtcctgc ggaatctgga taaaagagaa gcccaatctg
    10741 aaatatttaa ggaagatcga tataccataa gcagcgagaa tggagctgat ctgaatcagg
    10801 tacactgcac cctcggtttt taacagatca ctctgataga tcatccccac cagattataa
    10861 acataagaga ttgtaagctg cagaaccgca taagccgtaa tccctgcccc tgcaacaaat
    10921 gaggaatgac tgaatttaag tctgtacaca tatttgataa aaatcaaaaa gaacaaatat
    10981 tgaatcggga gatcaagctg ggggatctcg attaagagcc tcatcacaaa ggagaacaga
    11041 gcgataaata ctgcaaaagc agtcacttta tagcgatgtg accagagagg aagcctgtaa
    11101 agggagatca ttagagcaaa catggcgagg gcgtcaaaaa tcccaaggcc aatataaaca
    11161 taagaagacg acaaatcccg caccatcctt tacttattaa ctaaattata gggaagtgca
    11221 gaggaaagtt ctagtacttt ctaaatagaa tttatgaata tatgaaagta tttttagtag
    11281 gatcttcccg aacgtatgga tattattgta taattagtta acatttaaac ggggagtgat
    11341 tatctgtgaa aagattggat tcattcgaaa gaattctaat gctctttgct gcagtcatcg
    11401 tcctcttcat tatcggctcc tgtatggctt ttctctattt ctcttcactt gtatctccat
    11461 gataccaagg attaatatga accagcacct cttctacgta acttaccccg ctctttatcg
    11521 aattccgaat ttccttgcta acgtcatgtc cctgctgaac ggtcagctca ctcggaatac
    11581 taactctgac atcaacaata atataattcc ctaattctct tgcccgaatc cgatctatcc
    11641 gtctcacata ttcaacttgg ttcacaatct gatgaatgga gtccagcttt tcttgatcaa
    11701 tgttcttttc catcaggata tccacagatt cccgccccat cttataggcc agcttgatta
    11761 cgaagtaaga tacgaccagc cccgcgatag gatctccata tttcgtgaac ggaatatcat
    11821 aataatcacc tagcagcgca agaccaattc ccgcacaagc agccgctgac gcatagacat
    11881 ccgcaagatg gtcgtaggcc gtggccatca gacttttact gttctctgct ctacctatcc
    11941 gaatgcaata tacgtacaat acctgcttcc aaatcaagga aatcaacgcg gcggacaggg
    12001 cgataatgct tgcctcctcg gcgggagcga agaaagactc gatagacttg actatcatca
    12061 gaattgcggc tagagccaga attagcgcta ctaccgcgga agctagaacc tctgccttac
    12121 cgtgaccgta agggtgatcc tcatctgcag gctttttcga gatccgggta gaggtgagcg
    12181 cagcaaaaga agccactaca tctccagcat tatgtatacc gtctgcaatg agaacttggc
    12241 ttttgaacag gacgcccaca aaaattttaa ttccagtcag aaacaaattg ctgatcaagc
    12301 tgatccatac tgccacaaat gttttgttag ctgcttgcat tcttgaacat accgccttgt
    12361 tagtgatttg tcgtacatct ccccggctct ggccggtcaa tctatcttaa ctagaggaca
    12421 ccgtgtgggt ctagagaaac agtgttgttg gcagccttaa tcaaaagaca attgcaactg
    12481 tattggtatt ttcaaaattt attggataga tgcaacactc gccctgacct ggcttcccaa
    12541 ccacagaaaa aagccactat accgcgtata cgctcggttc atggctcttt cgcagatata
    12601 tttcgaatag gttcaggagt ttttggttct tgaggtgaat ttggcaagaa tagctccaag
    12661 agttccaata tcaaccgggt cctccgcttt ccagtcgctg ctgattccag catgatcgat
    12721 cagccactgt ctgccggatt ccttccaggc tggaacttca ggattgtgac caggcggctt
    12781 cgatccattg ttgcctttct tgtagacagc catcagctca gcctcacttc ccctatattc
    12841 attaagatcg acatttccac cgatccccgg cacggtgcct tcactcgtat actggaggaa
    12901 ctcccaggat ttccagcctg acttattcac gggcggcaca ttgctgtaat aagcgtacca
    12961 gagcggcaca tctgcaagac ttgagtccag atatccctca atgaagctcg gatacgtgta
    13021 caggagcggg gttctgccag tccgccgctt gaattcatct acccaggcgc gcaccgtggc
    13081 agtcacattg gcccgagtcc ctgcctcctt ggtctcaatg tcgaggacaa agggcagctc
    13141 gaaagtgtcc agtcctcctg cctgattaat tacgcttagg aaatgatcca cctccgcttt
    13201 cacatccgca ggtttggctg ctctggtgaa atggtacgct cccaccagga gtcctgctga
    13261 cttcgctccc ttcaaattat tgaagaattg attgtccgtg taacggctgc tctccgtagc
    13321 tttaataaat acaaaggatt tgcccgcggc tctcaccttc cgccaatcaa tagccccctg
    13381 ccagtgggag acatcaatac cttgcgcatg attcccgctt ctggtctgca tacaatccct
    13441 ccttttatct taagacagca tatgctagtt aagagagcgc cgtatcggcc tgtaccctta
    13501 ctccataact tttcattact cttctgatcc aaatattcca ccagcgttct cgaatatata
    13561 taaatttacc cttatcccag gcaattagaa ctaatccaca ggtgatcttc cggcttgtga
    13621 tataatcgga aataattaca aatctcgcgg aggtcatgat gtctaaattc attctttttt
    13681 ccgcattgtg gtggcttgtt gggaacccat ttctggcgat tatcattctg ctggccatta
    13741 tttatgtgct tgaccggcaa tttgtcggcg tattcccaag tgtgacaaga cccttccggc
    13801 ggatgagaga catatcctta ctccgtcagc agctcgcgct taatcatcat gacatttcag
    13861 ccaagcgcga tcttgcaaga cttctgcttg agagaaaaaa gtatagcgaa gcttattcct
    13921 tacttcaaga aatggagtct tcgtccaggg aatccgcaga atattgggat gatctcggaa
    13981 cagccgcttt aggacttggc caagtggaag aggcggaagc acatatgctt cgcgccctgg
    14041 agcttaatga acgagtccgt tacggacagc ccttccttaa gctggccgct gtctatcaga
    14101 acagaaatgc agagaagtct atctattatg ccgagaaatt cagtctaatt cactcgtctt
    14161 cctgcgaagc ctactttttg cttggcaatg tatatcaatc gttgaatcgg aaggatgagg
    14221 cgcgcagggc ttacacggaa tccatcagca tctaccgttc tctgcccaag tacaagaagc
    14281 gtcatgaacg caagtgggca ttacgaagct ggctcaagcg ccagcaggta tagccatcgg
    14341 gctgctgcat agttattgct taattcccac aaaaaagaac gagccttcag ctggcagaat
    14401 aatctgcttg ctgatggctc gttcttttat tattacaccc ataccaattc atggcgcctc
    14461 ttgagacgcg tggaggcctt atctactgac cagtctgcaa tcagctcatc ttggtatgtt
    14521 caaccttgga ggatttaaca tgatccgctt cgtcccgtgt agagaaaggc caccagttgg
    14581 cacttccgaa cagcttcacc ataaccggaa tgaagaatgg aagaataacc agggaataca
    14641 aggcaagccc cgtcagcacc acggtagcaa tctgcatcat ggacatgact cccgaaggat
    14701 acatggaagc gaaggttccg ccaagaatga ccgcagcgga cagaatgacg gttcccatat
    14761 ttctcatggc atgaagaatg gcatctccga ccttccacga tttgttctca ttgaaccggt
    14821 ccatcaggaa gatactgtag tctataccca gcgctacaag aattacgaat ccgaagaatg
    14881 gcgttgccca gctgatcccg gacatgccca taatcttcac gaagataagc tcagtaactc
    14941 ccatggaagt atagaaggtg agcaccagtg aagcaattag atagatcggc ataattaccg
    15001 agcgaagcag cagtaccaga ataatgaata taccggccag cattaatata accgtacgag
    15061 tataatcttc attagagatg gatctcagat cgttaaaagt actggatact cccccgaagc
    15121 caatctcggc ctcagccagc ttcgtacctt gaactgcgcg gtccaccgca gccttgatct
    15181 gatccacctg gctgatcgcc tctgtgccat acggattctc agagaagaca acatccaagg
    15241 tcataatctt gcgatccgca gacaggtagg tatcgaacaa ctgggttata tccttattgt
    15301 ccaaggcttc atcagggaca tagaagccgc cgagtccgct atctgcagtc ccgacctgat
    15361 tcaggtaatc cttggctgaa tcaagtccgc cggagacctt ggcaattccg tccgcactct
    15421 gactaagtcc gtcagtaagc ttcgagatct gtcccgagaa ctgggtgaat ccgttctgca
    15481 cctgcttctg accgttctca atctgagaca gcccgctcac taccgaaggg attcggtcaa
    15541 taatctgacc ttgaccggaa gccgcttgat ccagccccga ttcgagctgc gagataccgc
    15601 tgatcagctg atcaaatccg cccgctaatg cggactggcc tccggcgatt ttggccaagc
    15661 cttcattggc ctgcttgagg ccgccggcgg cttgattcag aggtgcctgc agctgcttga
    15721 gcccggcagc taactgagtc atacctttgc ccgtttctgt aactgtgccc cgaatagtca
    15781 aataatcggg gtctgacgcg agctcaggat acttgctctc caggctgctg aatttgccgc
    15841 tcaggccgtt caacccttgc gctgccccgg ttaattgctc gttaactctg gataacccgc
    15901 cgttaatcga gccaagtccc tgcccgatct gctgataaga cttcagaagc tgctgctgcg
    15961 cggcggccag ctgttgtgcg cttttcttcg cctgctgcag tccctgctta agctgacccg
    16021 ccccgtcaga gccgcttcgt attcccttct caatagctgt taacccgtta ttcagctggg
    16081 agattccatc cttcagcttc gccgtacctt cagcaagctt ccctgtgcta tcggccgcct
    16141 gtttgagctt cggctcgttc tcacttaacg agttactcgc tttagcaagg ccatccttga
    16201 tggtattcaa tccttcgttc cctttaccaa gaccttcacc gacggtcttc acctgctccg
    16261 tcagcttgaa gtccttcact tcatcaccag ttgggcggct taatccacgc acactcgcaa
    16321 ctccatcaac cgacttgact tcccggctaa tcttctccgc caaagtcata tactctgcag
    16381 aatccatacg ttcattgttc ttgattacaa tggaagtagg cagcgattct cccggctcaa
    16441 agctgtcaga gatgatattg aaggctttga ccgactcata attgtcgcca atctcttcca
    16501 tactgttgaa ggatacctta ccgctgtaag tgaacacgaa tggaagcgtg aatacagcta
    16561 caagcagaag cgccgcccag ggacgcttaa gtgagaaggc gccaaacata ccccagaact
    16621 tgttctcctt gtgctccaga gacccttttg caggccaaaa aatcttggta ccgagtaccg
    16681 ccatgaagaa cggcaccact gtgaggaggg cgagcagcat aacagcaacc cccaccgcta
    16741 ccgcagcggc tgacttatac agaatgaatt cagacaagcc aattgccgca aaaccgacaa
    16801 gaacagcaag acctgagaag aacaccgtct tccctgcggt acggtatgta gctataatgg
    16861 cttcccattt atcatccgta tgctgaagct cttccttgaa ccggcttata agcaggatac
    16921 agtaatctgt gcctatgccg aacataatcg cgaccatgaa gatctgggtg aaggtggaca
    16981 gcggaaagtc gaaagaatca accaggaatg caaccaccga ctgagccact acatagctga
    17041 tcccaacggt cagcagagga ataaatggag ccacgaacga acggaagctt atgaacaaga
    17101 tcagaagaat aaatacaacg gtaatgtact ccgatttctt aagtccgctc tcggagcttg
    17161 caatcgtatc ttcattaatc tgctcttggc ccgtcagata atgcttcact ggaacagaat
    17221 ccagcgtact gcggatatcc ttaacggtat ccttgagtgg acgtccgtcc atctcaacag
    17281 agagggaggt gagaatcgtc ttgccatcct tggagatcat cttatcggct gcgtccgggg
    17341 tagagaacgg gtctgttatg gacacaattc cgatcttggc tttggcatca ttcagtttct
    17401 gaatgccgct tttgatggaa tccttggcct cctgattcag aggattgtct tcatgaaaga
    17461 cgagcgcgat ctgcgtctct ttccctccgc ccttcatggc gctgatctcc ttcattaagt
    17521 cagacgcctc ggatgaagca tagccgggag gcacagacaa attgcctttc tgccggacca
    17581 gatccgccat ggaaggagct gttagcatta agcctacggc agcggcgatc cagaagagga
    17641 tcatccacca cctcgctttt agtataaatc tcatttattc tttactccct tcttcgaaca
    17701 gtctggccag cttctcaaag ctggtaatga aagactcaat ttcttcctga ttgaaatgga
    17761 ctagatattt ggccaccact tcctgtacct tctcatctgc cttgcttgaa atctcatgtc
    17821 caagctctgt gagtgacaga tatacaagtc tgcggtcctc cttatcacga gtcctctcga
    17881 caagtcccct gtccacaagc cgggtaatga tcgccgtaat tgagctcttg cccacacaga
    17941 aagcatccgc cagctccgtc gaagtacact cgtgctgtgt cttgatatag tacaaagtct
    18001 ggtactgatc aacggtcatg tcatcttgaa caatcttggc aatttcacta ctgagccgct
    18061 tggtcacggt agccgaagca gttacgtagc gctcaatcag ctctttggac tgctgttcca
    18121 ctcctcttcc cccattttgc ataatgattc aatcctcaaa tagttcgata atagaacttt
    18181 aaatctcccc ggcccaaaag tcaacttgaa catgcaaaaa aaccaatgaa accatgtagt
    18241 cgctacatca tttcgttggt tgctggccat tatttatatg cgggcattcc agatagattc
    18301 taaccgaact ccatgaatat cccgaactgc actattcctc ctgctcgtga agctccgcct
    18361 catatacaca gcggaagcgt tctactccat tagggagctt gctgctggtc tctataacga
    18421 acccaatatt tctataaaag tcaacgccct cctcgtctgt ctcagcgatg atcctgtccg
    18481 gcttctcttg gtacagaacc tcaagtatga tccctctgcc atacccttga tttctatgct
    18541 cgggagagat cgccagatga ttgataacca gcgcgttctg atcttccatc ttataaccga
    18601 taaggccaat caactcttct tcatgcttca gcgcgtacag ctgagcctct ctatcctcct
    18661 gataccgctt aatggcttcc gccagcaggt cttcatccga atagacagca tattcaagga
    18721 tccggcttat atccggactc tccacttgat tcttcacatt cactaacacg caatcagccc
    18781 cttctatgtc aaaaacatca cttgtaagtt tactctattg gcagggttaa caacaaattt
    18841 gttaaatcag tcaaactaaa atttcaaaat tcaaaagtaa acatattgca attcattaaa
    18901 ttcccagtat aatacttggt ataaagacaa tattgaaggt gatggttatg atgactcaag
    18961 cggcagttaa gctctcccag cgaattgatg attacctgga tcttctcaat tatgcgaagc
    19021 agattggtga tggggaatgg catactcaca ttttgctcac cttggagacg ttatataata
    19081 caagcgagga tgagctgcac aaggaaatgg aagaagaatt gtggaggcag tttgatcaaa
    19141 taaacgcccg gatgatggat ctatttattc agatccgccg aagcgcagat gataccacca
    19201 agcaaatgct gcttgaacag atgtggacgc tgaagctaga gcgggtaacc ctctcacaac
    19261 aaattaaatc tcattcgaaa tgatagctgg aaatcaaaaa agaggcatgc agtggactgc
    19321 tcagcctcga tgaaatgact catggcaatt ttggggattg ccgtgaacat tgcagttatt
    19381 caattggtat gattcatgca ttaatgagac ctaagcttca ttctgaaatg taagctgtta
    19441 tccggattac acggatgttt gtttcatctc gcgcatcatc ttcatcatca tagtcatcat
    19501 ttcatcgcag tcttgcattt tcttcatcat catgcccata tccatgtcca tgttcatcat
    19561 gtccatattt gagcagcatt ccatcatcat cttcatgctg ttcatcttag acatcatatc
    19621 ttccatacac atgttcatca tcatttgcat gcacatttta tccattcatc tcgcctcctc
    19681 tcttgtgaaa tatttcctat ttcaaaatac tatattccaa gcctatttgc aagagttttc
    19741 cacttgtttt tttataagtt tcatagtata atatcatact tttcacattt atcctgtagg
    19801 tatttgcggt gaaattatat aaaaaagaat aacctcccta gggaggttac agattgcaga
    19861 caaacttctt gttcccgtta ggaacacagg agtttgtctt tgtttttttc tgtaagagat
    19921 cataaataaa gccaaatatc gctttgagcc accggacttc cagagccagg tggctaactt
    19981 tttgaggttc atgcaagcaa aaacgagcat cgcctgcatg gaaactttac gaagtcctcg
    20041 taaagtcgtc cagcgcatgc catgcttttc ctttagatct gcaaatacgc gctcaatcgt
    20101 ttccttgcgc tgtgagtaaa tttgtttgtt ttcatcggta tgccgaaggt ggtctgcttc
    20161 ttccagatag tcagcccaaa tatggcggct aattcgctta gtgaagtcct tgctttcggt
    20221 acactgactc aagaaggggc agtctttgca tattgtggga tcggaacgat acatcttgta
    20281 cccttcccgg ttcgtcaatt cataggttag aaactcatgg ttcggacaga tataggcatc
    20341 gtagtgctca tcgtatacgt aatcatattt cttgaaaaag ccatcctttg tacgaggtct
    20401 tgtgtatggc ataacaggcc gtatcccgtc atcgatcagc aatttactaa tgtagggagt
    20461 cttgtatcca gcgtcaactg ctacagctgt gggcttgccc agagacttct ttacgagctc
    20521 aagcacatcc t
//
