LOCUS       NZ_CP084530            20876 bp    DNA     circular CON 20-MAY-2024
DEFINITION  Paenibacillus sp. YPG26 chromosome, complete genome.
ACCESSION   NZ_CP084530
VERSION     NZ_CP084530.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus sp. YPG26
  ORGANISM  Paenibacillus sp. YPG26
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 3966665)
  AUTHORS   Ma,K., Chen,W., Yan,S.Q., Lin,X.Q., Liu,Z.Z., Zhang,J.B., Gao,Y. and
            Yang,Y.J.
  TITLE     Genome mining reveals polysaccharide-degrading potential and new
            antimicrobial gene clusters of novel intestinal bacterium
            Paenibacillus jilinensis sp. nov
  JOURNAL   BMC Genomics 23 (1), 380 (2022)
   PUBMED   35590262
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3966665)
  AUTHORS   Ma,K. and Yang,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2021) College of Veterinary Medicine, Jilin
            University, Xi'an Road 5333, Changchun, Jilin 130062, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT v. v5.0.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023704175.1-RS_2024_05_20
            Annotation Date                   :: 05/20/2024 03:35:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,770
            CDSs (total)                      :: 3,645
            Genes (coding)                    :: 3,614
            CDSs (with protein)               :: 3,614
            Genes (RNA)                       :: 125
            rRNAs                             :: 11, 11, 11 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 11, 11 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 31
            CDSs (without protein)            :: 31
            Pseudo Genes (ambiguous residues) :: 0 of 31
            Pseudo Genes (frameshifted)       :: 17 of 31
            Pseudo Genes (incomplete)         :: 17 of 31
            Pseudo Genes (internal stop)      :: 6 of 31
            Pseudo Genes (multiple problems)  :: 7 of 31
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:27:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1704291
            Orig. end                         :: 1725167
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084530.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Yong-Jun Yang Lab, College
            of Veterinary Medicine, Jilin University, Changchun, China.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20876
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="5"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20876
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20876
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10876](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10876
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    692..705
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.49"
                     /tool="antismash"
     misc_feature    825..841
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.37"
                     /tool="antismash"
     gene            1090..1866
                     /gene="spoIIIAF"
                     /locus_tag="LDO05_RS07925"
                     /old_locus_tag="LDO05_07960"
     CDS             1090..1866
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAF"
                     /inference="COORDINATES: protein motif:HMM:NF021121.4"
                     /locus_tag="LDO05_RS07925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_07960"
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_251378301.1"
                     /transl_table=11
                     /translation="MTWIANWLKEIIFVVLLAGFVDLLLPNRSFERYVKLVISLLILLT
                     LMSPVVKLIGGDPVQELQTALNQTTKELDPNMDSSSTDQIVQQGLALRKKQEAQSLEWA
                     GQEVAREMEQQIEHKAGIQVERVKVTLAVNNQTSRQEDTVQQPAGKPVIKEVEVYLAAK
                     NPPVTDGTPSSEGIQSTAISVPAIKQVEKVDITVKQDGALDTKHPGTGTSKDAEVQSQS
                     GIHTTRNLEITNQLTKDWGISRTIIKIHEPEEQSGQ"
     gene            1881..2528
                     /gene="spoIIIAG"
                     /locus_tag="LDO05_RS07930"
                     /old_locus_tag="LDO05_07965"
     CDS             1881..2528
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018751513.1"
                     /locus_tag="LDO05_RS07930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_07965"
                     /product="stage III sporulation protein AG"
                     /protein_id="WP_251378302.1"
                     /transl_table=11
                     /translation="MVKWWKKLEQWLGAGPEGSKKINTLRLLIILGLIGVAFMLISSFV
                     NVKKIDTGGAGREPPVQNQSQTTSAVSQPEDGDSSFDNIEGNLESRTKEILEKIVGVGT
                     VDVMVTVDSTEEVVVQRNMKDSQEQTDETDAGGGKRHVTQYTRDGQIVTYEVSGDSKPL
                     ITKKIKPRIRGVLVVARGAENKTVKQLIVDAVEKGLNVASYQISVVPRKGTQ"
     gene            2561..3319
                     /locus_tag="LDO05_RS07935"
                     /old_locus_tag="LDO05_07970"
     CDS             2561..3319
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427501.1"
                     /locus_tag="LDO05_RS07935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_07970"
                     /product="SpoIIIAH-like family protein"
                     /protein_id="WP_251378303.1"
                     /transl_table=11
                     /translation="MKTNRQTIWLVSMLSLMVILSAYYLFTEESAVKAPKVADGQQVSV
                     QDNTAAKDTALTEAQEDLVVKEVTDISDKVTAAEPGAAADNSKNDAAKKDTAAAEVKSP
                     EKTAPADQSAVSSEDPQKDAEVLKKIEAQGTAGNDAITNYQYQRNEENKKINDKLTQII
                     ADQTKSAEESAKAQRELAALEDKEAKISDIEEKLQQQYANAAVTPKDDGYTVVVLSDKL
                     EAKQAVSIVDLVIKELGVAQDKVRVQYVTQ"
     gene            3498..3995
                     /gene="accB"
                     /locus_tag="LDO05_RS07940"
                     /old_locus_tag="LDO05_07975"
     CDS             3498..3995
                     /EC_number="6.4.1.2"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310822.1"
                     /locus_tag="LDO05_RS07940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_07975"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="WP_251378304.1"
                     /transl_table=11
                     /translation="MFKLNEIKELIKLVDQTSIHELEIENEGTRLAIRKPGKTEIVQVQ
                     SAAAPVTHVTAAPASVQIQPAAEPAAAPSGEGAPRADANANLHTIVSPMVGTFYRSSSP
                     DKAPYVNVGDKVGDKTTVCIIEAMKLMNELEAEVKGEIVEILAENGQLVEYGQPLFLVK
                     PE"
     gene            4053..5396
                     /gene="accC"
                     /locus_tag="LDO05_RS07945"
                     /old_locus_tag="LDO05_07980"
     CDS             4053..5396
                     /EC_number="6.3.4.14"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004075 - biotin carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371779.1"
                     /locus_tag="LDO05_RS07945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_07980"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_251378305.1"
                     /sec_met_domain="RimK (E-value: 4.6e-07, bitscore: 27.4,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.4e-08, bitscore:
                     32.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 2.9e-10,
                     bitscore: 37.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFHKILIANRGEIAVRIIRACRELGIQSVAVYSEADKDSLHVRL
                     ADEAYCIGPTLSKDSYLNFTNLMSVATLTECDAIHPGYGFLAENADFAEICGSCNITFI
                     GPSPDAITRMGDKAVAKQTMIEAKVPVIPGSDGLIEDMDQAIMVARDIGYPVIIKATAG
                     GGGKGIRIAEDEDSLVQQITTAQQEAQKAFGNAGVYLEKYLTGMKHVEIQIIADRHGNV
                     AYLGERDCSVQRRRQKLVEEAPCPILSPEKRKEMGEAAVRAAQAVDYSGAGTLEFLLGP
                     DGQFYFMEMNTRIQVEHPVTEMVTGIDLIKEMISVAEGNPLSFSQEDVIINGWSIECRI
                     NAEDPSRNFMPSPGKIGFYLAPGGPGVRVDSGAYPGYVITPFYDSMIAKLIVWAPTREE
                     AIAKMKRALSEFAVEGIHTTISFHQKLLEHPTFIRGDFDIKFLEENEI"
     gene            5509..5916
                     /locus_tag="LDO05_RS07950"
                     /old_locus_tag="LDO05_07985"
     CDS             5509..5916
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007430927.1"
                     /locus_tag="LDO05_RS07950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_07985"
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_251378306.1"
                     /transl_table=11
                     /translation="MSTFPTEYERTEIGEIQIAPEVIEVIAGLAAVEVNGVAGMSGGFA
                     GGIAELLGRKNLSKGVKVEVGQLEAAVDVSVIVEYGNRLPEVATEIQRNVKRSIETMTG
                     LTVVEVNVHIHDVIFKTAEKIEESELSHRVK"
     gene            5989..6528
                     /gene="amaP"
                     /locus_tag="LDO05_RS07955"
                     /old_locus_tag="LDO05_07990"
     CDS             5989..6528
                     /codon_start=1
                     /gene="amaP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014282227.1"
                     /locus_tag="LDO05_RS07955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_07990"
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="WP_251378307.1"
                     /transl_table=11
                     /translation="MAKILDRLLLFIYSFSIGILSVIAILLFTEAVPFHIDSSYEKTLL
                     NVSIAVAAVLFLLSIRFFYISIRRDRASLPSIDQRTEFGDIQISVETIENLSLKAASRV
                     RGIKDVKTRIKITESGLSIIIRALVDGESSIPTLTEEVQRQVHDHVQEITGIPVSYVSV
                     YIANLVQSPTIKSRVE"
     gene            6543..6776
                     /locus_tag="LDO05_RS07960"
                     /old_locus_tag="LDO05_07995"
     CDS             6543..6776
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014282226.1"
                     /locus_tag="LDO05_RS07960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_07995"
                     /product="DUF2273 domain-containing protein"
                     /protein_id="WP_251378308.1"
                     /transl_table=11
                     /translation="MLWKQLWESHRGRLLGLATALLLCPIYLFFGFWNMLFCALLLYIG
                     YTIGKYKDLGQGSFIPWAEIRDWLGARWRPFK"
     misc_feature    complement(6894..6914)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     gene            6990..7436
                     /gene="nusB"
                     /locus_tag="LDO05_RS07965"
                     /old_locus_tag="LDO05_08000"
     CDS             6990..7436
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009225786.1"
                     /locus_tag="LDO05_RS07965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_08000"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_251378309.1"
                     /transl_table=11
                     /translation="MKRRLAREISVQSLYQMEMNDVEANEAVTMLLSEAGGENESEVEL
                     SDMGTPEFVLELVNGVWEKKSEIDALLGDYLKGWQISRLSRVDRQVLRLAAYEMIYRDD
                     APAKVVVNEAIELAKHFGTAESGKFVNGVLGKMIQDLDQLKNKQ"
     gene            7483..8340
                     /gene="folD"
                     /locus_tag="LDO05_RS07970"
                     /old_locus_tag="LDO05_08005"
     CDS             7483..8340
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007129727.1"
                     /locus_tag="LDO05_RS07970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_08005"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_251378310.1"
                     /transl_table=11
                     /translation="MTAQIISGKQVAEEIRQGLREEMERLAETGFKPGLAVVIVGEDPA
                     SQVYVRNKDKACHDLGYYSEVHKLEESTTQEELLALVNKLNQQSNIHGILVQLPLPKHI
                     DEKSVINAIAVEKDVDGFHPVNVGNLVIGDDSLLPCTPAGVIELIKRTGLDMAGKHAVV
                     IGRSNIVGKPVALLLQRENATVTMCHSRTANMKELTLQADILVVAVGRANFIDASYVKP
                     GAVVIDVGVNRLDNGKLAGDVDFDSVKEVSGPITPVPGGVGPMTITMLMNNTMVAAKRL
                     SGLE"
     gene            8367..9746
                     /gene="xseA"
                     /locus_tag="LDO05_RS07975"
                     /old_locus_tag="LDO05_08010"
     CDS             8367..9746
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371774.1"
                     /locus_tag="LDO05_RS07975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_08010"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_346657643.1"
                     /transl_table=11
                     /translation="MPVNQRIFSIKELNRYIRMKLESDTLLSEVWIRGEISNFTHHSSG
                     HMYFTLKDKDSRIKSIMFASHNQRLPFIPKEGSRVIARGNVSVYERDGQYQFYATHMQP
                     DGIGSLYLAYEQLKKKLEDEGLFEQSRKRALPRYPKTIGVVTSPTGAAVRDIIITLQRR
                     YPQVPIILHPVLVQGKQAAPSIVKALRTLNSMGEADVIIVGRGGGSLEELWAFNEEIVA
                     RAIYESAIPVISAVGHETDFTIADFVADLRAATPTAAAELAVPHAAELRALLGQREREL
                     QQGLKHRLARARERLARLQRSPVLVHPRRSLLQHAERLDMLKHRLASRMHARALLTSER
                     RGRLHARLLRFHPQEQLQYAKRRQSDAARQLRQAMLAVLKDRSAQLTAGIRQLDALSPL
                     KVMGRGYSLVYDEQGSRLIKSLDEVQPGDMLKIKVTDGELDCQVWGMQREGDSHGTGEG
                     H"
     gene            9724..9978
                     /gene="xseB"
                     /locus_tag="LDO05_RS07980"
                     /old_locus_tag="LDO05_08015"
     CDS             9724..9978
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017687599.1"
                     /locus_tag="LDO05_RS07980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_08015"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_251378312.1"
                     /transl_table=11
                     /translation="MEQEKDINFEEAMSQLEEIVSKLEHGDVPLETAIDLFQRGMQLSQ
                     LCGQKLVQVEGKIEMIVESDGEITKKPFAAPVESGESGE"
     gene            10001..10876
                     /locus_tag="LDO05_RS07985"
                     /old_locus_tag="LDO05_08020"
     CDS             10001..10876
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639053.1"
                     /locus_tag="LDO05_RS07985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_08020"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_251378659.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9.5e-61, bitscore:
                     203.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEINKLVTGGLQDFIPGEWVVPSSLHEAMRYSLMAGGKRIRPLL
                     VIAAAESLGGSREAALPVACAVEMVHTYSLIHDDLPAMDNDDFRRGKPTNHKVFGEASA
                     ILAGDGLLTHAFYSIAQASRRYHVPAEQTLAIVEELSLYAGPKGMVGGQAADMEGEQGI
                     TSLDQLKYIHMHKTGDLIVFSLKAGGRIASASLEQLRALETFGRSIGLAFQIQDDILDL
                     IGNEEKLGKKTQSDVVMNKVTYPYFIGLEESRAEVDRLTLLAKEAIGGGTIPHPDRLLQ
                     MADFLLNRDH"
     gene            11022..12929
                     /gene="dxs"
                     /locus_tag="LDO05_RS07990"
                     /old_locus_tag="LDO05_08025"
     CDS             11022..12929
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639052.1"
                     /locus_tag="LDO05_RS07990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_08025"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_251378313.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.3e-124,
                     bitscore: 412.5, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.8e-06, bitscore:
                     25.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLSQIHEPNDLKKYSVDELDNIAQEIRDFLIQKLSATGGHLAPN
                     LGVVELTLALHYCYNSPDDKFIFDVGHQAYVHKILTGRMEQFDTLRKYKGLSGFVKRNE
                     SEHDVWEAGHSSTSLSAAMGMALARDLKGGTNKVVAIIGDGALTGGMAFEAMNHIGHEK
                     KNLMVILNDNEMSIAPNVGAMHNYLSKIRSDRTYLRAKDEVELLLKKIPAIGGKLAKTA
                     ANLKDSLKYMIMNGVLFEELGFTYLGPVDGHDLPKLIEVFKQADNVTGPVLVHVLTTKG
                     KGYSPAEADSHKWHGISPYKIESGKVLKAVGNPMYTEVFGQTLIELAEQDSRIIAVTPA
                     MPGGSGLLKFAEKFPDRMIDVGIAEQHAATMCAALAMEGMKPVYAVYSTFMQRAYDQII
                     HDICRHNANVMFAIDRAGFVGADGETHQGVYDIPFLRHIPNMVLMMPKDENELRHMMKT
                     ALEYNDGPIAYRYPRTNVPGVSMDVELVPIPIGTWEKVREGDGTAIIAVGTMVQVAEEA
                     AEQLKREGIQAAVINARFIKPLDETMLLELAKTHAKMVVIEESTIAGGLGSAILEFYAQ
                     QGISGLDIRLMGVPDKFIEHGSIKEQCQEVGLTTEALIEQVQKLRNDHHFAFGKKTLPS
                     "
     misc_feature    complement(11056..11065)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            12969..13811
                     /locus_tag="LDO05_RS07995"
                     /old_locus_tag="LDO05_08030"
     CDS             12969..13811
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018751500.1"
                     /locus_tag="LDO05_RS07995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_08030"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_251378660.1"
                     /transl_table=11
                     /translation="MAGSKERIDVLLVEQGFFESREKAKAAIMAGLVYGDTERIEKAGT
                     KIPRDTQLNVKGAIHPYVSRGGLKLAKAINTFGLDMSGRVMLDIGASTGGFTDCALQNG
                     ASYVYAIDVGYNQLDWSLRNDERVNVKERMNFRYMTPEDLDGPVPDFASIDVSFISLKL
                     ILPPLKSLLKRPADVAALIKPQFEAGRDKVPKTGVVRDAKVHQEVMEQVLTFAVEEGFG
                     IKGLTFSPITGGEGNIEFLVHLRLDPDEQNEGDSKLNIPELARNVVEEASGTFNPQHK"
     gene            13974..14429
                     /locus_tag="LDO05_RS08000"
                     /old_locus_tag="LDO05_08035"
     CDS             13974..14429
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018751499.1"
                     /locus_tag="LDO05_RS08000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_08035"
                     /product="hypothetical protein"
                     /protein_id="WP_251378314.1"
                     /transl_table=11
                     /translation="MQADGFLIVVVVAILLYLIYRSVQSWLRRPALLRRGLHFDLNEDI
                     PGHPAVELLKEHGYEVISGKLRVPLTFMVNHTKLHSRLFIDYVATREDELYLVRLARAR
                     QPLEWTGSGVRQELLPFLLLYPDCSGLLYIDAEHSEIKVIVLDSDDE"
     gene            14460..14909
                     /gene="argR"
                     /locus_tag="LDO05_RS08005"
                     /old_locus_tag="LDO05_08040"
     CDS             14460..14909
                     /codon_start=1
                     /gene="argR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014282217.1"
                     /locus_tag="LDO05_RS08005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_08040"
                     /product="transcriptional regulator ArgR"
                     /protein_id="WP_251378315.1"
                     /transl_table=11
                     /translation="MKGQRHIKIREIITGQEIETQDELVEALREAGYQVTQATVSRDIK
                     ELLLIKVPMDDGRYKYSLPVDQRANPVQKLRRYLVDSFVHIDYTGNLVVMKCLPGTANS
                     VAVLIDNMEWPEILGTICGDDTILIICRTEEYSKSIINQIMSFIP"
     gene            14931..16673
                     /gene="recN"
                     /locus_tag="LDO05_RS08010"
                     /old_locus_tag="LDO05_08045"
     CDS             14931..16673
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639048.1"
                     /locus_tag="LDO05_RS08010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_08045"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_251378316.1"
                     /transl_table=11
                     /translation="MLVHLSIRNLAVVESVDVTFHRGFHVLTGETGAGKSIIIDALGFI
                     AGGRGSADLIRYGCDKAEIEASFDLRGNHPAWSTLEGLGIHADPSEELIIRREISAQGK
                     SISRINGQMVNLSMLREIGDQLINIHGQHEHQTLLRPERHLHLLDAFGSDILAPLKASY
                     QATYSAFVKVEKEWNELQKSSQQTFQMLDMYRYQIEEIAAAKLKAGEDELLAEEKVKLS
                     HSEKMMDSISGAYELLNGSHGLEAVAKAISRFEDIAGYDSKGIGPILEQLQSAYYQLED
                     ASFALRNYRDGIEVNSGRLDEVQERLDFISTLKRKYGDSIERILAYYDQITQETDTLEN
                     KDEILERLSARREKLLTQLLEEGEALSQARQRCADDLAIQIEAELKDLQMGRTSLKVKF
                     GRLEDPSGVEWRGQRIRVSRQGLDTAEFLISPNPGEPLRPLGKIASGGELSRMMLALKS
                     IFARHDEVPVLIFDEVDTGVSGRAAQSIAEKLYKLSATCQVFSITHLPQVACMADNQYL
                     IEKTVHDGRTMTQVEALTETGRVKELARMLGGVEITEKTLHHAQEMLGLARDQKAEVTC
                     RSND"
     gene            16769..18115
                     /gene="spoIVB"
                     /locus_tag="LDO05_RS08015"
                     /old_locus_tag="LDO05_08050"
     CDS             16769..18115
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIVB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018755143.1"
                     /locus_tag="LDO05_RS08015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_08050"
                     /product="SpoIVB peptidase"
                     /protein_id="WP_251378317.1"
                     /transl_table=11
                     /translation="MNPNLRKRMLGLLFTFFFCFLGSAAAGEVSNPLMPNELRLVEGEL
                     ARIESALPVLAQVSVDRPDVVQLGGDAKSSAGDVSFGKGKPLLLSSQSAGEAHLRMKLF
                     GQIPLKTVKVNVIPDLKVIPGGQTIGVKLKSSGILVVGHHLVSMSGNSKQSPGEKAGLQ
                     LGDRITHMNGIELKDVKDVASIVEQAGQQKQPLEVTYKRGEHVYRTTLSPVFDEQDKTW
                     RLGLYIRDSAAGVGTLTFYAPEQGVYGALGHVITDMNTQTPIVVGSGQIVESSVTSISK
                     SENGEPGEKRAHFIKEGRVLGNIEQNTDFGIFGKMSTNPEHSLYGDPIPVGFAEHVKEG
                     PAEILTVVSGQKVERYSIEIVHVSSQNAPQTKGMVIRITDPRLVNKTGGIVQGMSGSPI
                     IQNGKLIGAVTHVFVNDPKSGYGCFIEWMLQDAGVMINNSGQAKNLKAS"
     misc_feature    18121..18136
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
     misc_feature    complement(18174..18187)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.37"
                     /tool="antismash"
     gene            18315..19130
                     /gene="spo0A"
                     /locus_tag="LDO05_RS08020"
                     /old_locus_tag="LDO05_08055"
     CDS             18315..19130
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /GO_process="GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /gene="spo0A"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345656.1"
                     /locus_tag="LDO05_RS08020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_08055"
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="WP_251378318.1"
                     /transl_table=11
                     /translation="MQNIEVLLADDNREFTNLLAEYISGQEDMTISGIAYNGEEALQMI
                     ENGSKIPDVLILDIIMPHLDGLGVLERLRDMNLSPQPKVIMLTAFGQENITQRAVQLGA
                     SYYILKPFDMEVLAQRIRQLVGIPSQSLGSQSSTSSSSLFKSNVVPMAKGKNLDANITS
                     IIHEIGVPAHIKGYQYLREAITMVYNNIEILGAITKTLYPAIAEKFKTTPSRVERAIRH
                     AIEVAWTRGNIDSISHLFGYTINISKSKPTNSEFIAMVADKLRIEHKVS"
     misc_feature    19240..19253
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.98"
                     /tool="antismash"
     misc_feature    complement(19241..19254)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.16"
                     /tool="antismash"
     misc_feature    19241..19255
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.84"
                     /tool="antismash"
     gene            19384..19914
                     /locus_tag="LDO05_RS08025"
                     /old_locus_tag="LDO05_08060"
     CDS             19384..19914
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019912743.1"
                     /locus_tag="LDO05_RS08025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LDO05_08060"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_251378319.1"
                     /transl_table=11
                     /translation="MSSRQERLIIRDAVPEDRASIEKLMVEAYGQYEQSMPEERWKPYI
                     KSIRESVYTEGPAARIVAELNGEIVGSLLVFLSSEAAYGRPDLKIESPIIRLLATSPKA
                     RGRGIATQLISETVRRAKLWGADTIHLHTSDVMAPAIRLYEFLGFERAREKEMQNGDIL
                     VKCYRLQLQPIEA"
ORIGIN
        1 tgaactgccg acggatcagg tcgaagctta ttggaagcat ctgatgaagg attacggcgg
       61 attctttcca gatgagaagg tgccttcctt tatggacatg ttactgcccg gaggacagga
      121 attcaatgtg aaatccggcc tctcggcact gctcaaatat atgtggcatg aggttctgta
      181 caacggacat atcctggtta ccattgtcat tctgactgtg ttcagcttga ttctggagac
      241 gctgcagacc gcattcgaac ggggaaatgt cagcaaggtg gcctactcga tctgttacat
      301 ggtcattcta attctggcaa tcaacagctt caatgtggcc atcggatatg ccacagacgc
      361 catcaaggac atgattgact tcatgatggc gatggtgccc ctgttgttta cgatgctggc
      421 ttcgatgggg aacatcgtca cagtaacggt tacgcacccg cttgtagtgt tcatggttca
      481 cacggtaggt acgctcgtat acacggtggt gttcccgctg ctgttcttct cggcgctcct
      541 tcatatagtc agctccttat cggacaagta taagctcaca cagctggcta atctccttcg
      601 taccatcagt atgagcttgc tcggggttct gcttacgatc tttctaggag tcatttctgt
      661 aaaaggaatt accggctcgg ttgccgacgg ggtaaccctg cgtgcagcca aatatgtaac
      721 ggggaacttc gttcccgttg tagggaaagt gttcgcggat gcaacggata ccgtcatctc
      781 cgcatccctg ctggtgaaga atgccgtggg ccttgtgggt gtcattgtaa ttttgttcct
      841 gtgcgctttt ccagccatca aaattctgac actggcatta atctataatc tctccgcagc
      901 ggttatgcag ccactgggtg attccccggt tgtaacgtgt cttgagacca ttggcaagag
      961 catgatctat gtgttcgcag ccatggctgc cgttggcttg atgttctttc tggccattac
     1021 catcatgctt accgccggaa atataacggt gatgatgcga tgacaatgga ctaagagagg
     1081 ggtgaatcca tgacctggat tgccaattgg ctgaaggaaa ttatatttgt ggttctcctg
     1141 gcgggctttg ttgacctgct tctgccgaac cggtcgttcg agcgttatgt caagctggtg
     1201 atcagtctgc tcatcctgct tacgctaatg tctcctgtgg tcaaactcat tggcggcgat
     1261 ccggtgcagg aactgcagac ggcgctcaat cagacgacga aggagcttga ccccaacatg
     1321 gacagcagca gtaccgatca gattgttcag cagggattgg cactccgcaa gaaacaggaa
     1381 gcacagtcgc tcgaatgggc aggccaggag gtagcaagag aaatggagca gcaaattgag
     1441 cataaggcgg gaattcaggt ggagcgggtg aaggtcacac tcgcagtaaa taaccaaaca
     1501 agccgacagg aggataccgt gcagcagcct gccgggaagc ctgtgatcaa agaagtggaa
     1561 gtgtatctcg cagccaaaaa tccgcctgta actgatggaa caccatcaag tgagggaata
     1621 cagagtactg ccatatcggt tcctgctatt aagcaggttg agaaggtgga cattactgtc
     1681 aaacaagatg gggcattgga tacgaagcat ccgggcacgg ggacatcgaa ggatgccgaa
     1741 gtacagagcc agagtggaat ccataccaca agaaatctgg agattacgaa ccaactgaca
     1801 aaggattggg gtatctcaag gacaatcatc aagattcatg aacctgagga acaatcaggg
     1861 caataaagga ggtggagagc atggtgaagt ggtggaagaa gcttgaacag tggctggggg
     1921 caggaccgga aggcagcaaa aaaataaaca cattgagact gcttattata ctcggactca
     1981 ttggagtggc cttcatgctg atcagttcat ttgtaaatgt gaagaaaatc gataccggag
     2041 gtgcagggcg tgaaccaccg gttcagaatc agtctcagac cacttcggct gtctcccagc
     2101 ccgaagatgg ggacagctcc tttgacaata tagagggcaa tctggagagt cgaaccaagg
     2161 aaatactgga gaaaatcgtc ggagtaggta cggtggatgt gatggttacg gttgactcaa
     2221 cggaagaagt tgtggttcag cggaatatga aggattccca ggaacagaca gatgaaacag
     2281 acgcgggagg cgggaagagg catgtaaccc aatatacccg ggatggacag attgtgactt
     2341 atgaagtgtc gggggactct aagccgctca ttacgaagaa gatcaagccg agaatccgcg
     2401 gggtcctcgt ggtcgcacgg ggggcggaga acaagaccgt caagcagctg attgtagatg
     2461 ccgttgagaa aggcctgaat gttgcatcct atcaaatatc tgtagttcca cgtaagggca
     2521 cacagtaaga gggttgatta ataattagga ggtatattta atgaaaacga acagacaaac
     2581 aatttggctt gtgtccatgc ttagcttgat ggtgatcctc tcggcatact acctgttcac
     2641 agaagagtca gcggtcaagg ctccaaaggt tgctgatggc caacaggtat ccgtccagga
     2701 taatacggct gccaaagaca cggctctaac cgaggcacag gaggatttgg tcgtaaaaga
     2761 agtaacggat atcagtgata aagtaacggc tgcggagcca ggcgcagcag cagacaatag
     2821 caagaacgat gctgcaaaga aagacaccgc ggctgccgag gtgaagagcc cagagaagac
     2881 agcacctgct gatcaatcag cagtgtccag tgaagacccg cagaaggatg ccgaggtact
     2941 gaagaagatt gaagcccaag gcacagcggg caacgatgcc attactaatt atcagtacca
     3001 aagaaatgag gagaacaaga aaatcaatga taagctcaca cagattattg cggatcagac
     3061 gaaatcagcg gaagaaagtg caaaggctca aagagaacta gccgccttgg aggataaaga
     3121 ggcgaaaatt tccgatattg aagagaagct gcagcagcag tatgcgaatg cggcggtaac
     3181 tccgaaggat gatggataca ccgtggtcgt gctaagtgac aagctcgaag ccaagcaagc
     3241 cgttagcatc gtggacctgg tgattaaaga gcttggagtc gcccaggata aagttagagt
     3301 gcaatatgta acccagtaaa catgtgaaat gcgtttataa aacgcggttt ctcagcaatt
     3361 aagaagcctt gcgcaagcag aagggcccaa gaatcttggg ctctttctat ttcttagact
     3421 tgtgatataa tacataatgc tatgttctaa gaaggccaag gcttgtgtgt tacaaagctg
     3481 aaggagtgaa actgacaatg ttcaaattaa acgaaatcaa agagcttatt aaattggtgg
     3541 atcagacctc gattcacgaa cttgaaattg agaatgaggg aacaagactt gcaatccgca
     3601 agccgggcaa gactgagatt gtacaggtac aatccgcagc agcgcctgta acgcatgtaa
     3661 ctgccgctcc cgcgtcggta cagattcagc ctgcagcaga gccagccgct gcgccatctg
     3721 gcgaaggtgc cccgcgtgcc gatgctaatg cgaacttaca tacgattgtc tctcctatgg
     3781 taggcacatt ctatcgttcc tcttcacctg acaaggctcc ttatgtcaat gtgggcgata
     3841 aggtcggcga caagaccacg gtctgcatta ttgaagcgat gaagctgatg aacgagcttg
     3901 aggctgaagt caaaggggaa atcgttgaga tcctggccga gaatggccag cttgtggaat
     3961 atggacagcc cctctttctg gtgaagccgg agtaatgaac gtaagaaggc ggtaatacac
     4021 gctatcttta gggtgccaag gaggatgcag acttgaaatt tcataaaata cttatagcca
     4081 accgcggtga aatcgcggtg cgaattatcc gggcttgccg ggaactgggt atccagtccg
     4141 tggctgtata ctcggaagcg gataaggatt cccttcatgt ccgtttagcg gatgaagcct
     4201 attgtatagg tccaaccctg tccaaagaca gttatttgaa ttttacgaat ctgatgagcg
     4261 tggcaacgct caccgagtgt gacgcaattc acccgggtta tggattcctg gctgagaatg
     4321 ccgattttgc agagatctgc gggtcctgca acatcacgtt tattggaccg tctccggatg
     4381 cgatcacccg catgggagat aaggcggtag ccaagcagac gatgattgaa gcgaaagtgc
     4441 ctgttattcc tggttcggac ggcctgattg aagatatgga ccaagctatt atggtagctc
     4501 gtgatatcgg ctaccctgtt ataatcaagg caaccgccgg tggcggcggc aaaggaatcc
     4561 ggattgcgga agatgaggat tcccttgttc agcagattac cacggcacag caggaggccc
     4621 aaaaggcttt cggcaatgca ggtgtatatc tggagaaata tcttacaggc atgaagcacg
     4681 ttgagattca gattatcgcc gacaggcatg ggaatgttgc ctatttggga gaacgggatt
     4741 gctccgttca gagacgcaga cagaagctgg tagaggaagc tccttgcccg attctaagtc
     4801 ctgagaaacg taaagagatg ggagaagcgg cagtgagagc agctcaagcc gttgattatt
     4861 ccggcgccgg tacgcttgag ttcctgttgg gccctgatgg acagttctac ttcatggaga
     4921 tgaacacccg gattcaggtt gagcatcccg taaccgagat ggttaccggg atcgatctga
     4981 ttaaggaaat gatctcggtg gctgaaggga acccattgtc tttctcccag gaagatgtca
     5041 ttattaacgg ctggtctatc gaatgccgta ttaatgccga ggacccgtct cgtaatttca
     5101 tgccgtcccc aggcaagata ggtttctatc tggcaccggg tggaccgggt gtccgtgtag
     5161 acagcggagc ttatccgggg tatgtgatta cgcctttcta tgattccatg attgccaagc
     5221 taatcgtatg ggctcctaca cgtgaggaag ctattgccaa aatgaagcgg gcgttatccg
     5281 agttcgcggt agaaggaatt cacaccacga tttctttcca tcagaagctg ctggagcatc
     5341 caaccttcat acggggggat ttcgatatta aatttctgga agaaaatgag atttaataac
     5401 ttggaccctg tttgtcataa tgagtccaaa atgatatagt atgtataata agtgcgcttg
     5461 cctactagta gcatccgcaa acttattgag aggtggatga agacgacgat gagtactttt
     5521 cctacagaat atgagagaac cgaaattggt gaaatccaaa ttgctcccga agtcattgaa
     5581 gtaatcgcag gtcttgctgc cgttgaagtt aacggtgtgg ctggcatgag cggcggattc
     5641 gctggaggca tcgcagagct gctgggacgg aagaacctgt ccaagggcgt taaggtcgaa
     5701 gttggtcagc ttgaggctgc agtcgatgta tctgtgattg tggagtatgg taaccgcctt
     5761 ccagaagtgg cgaccgaaat tcagcgtaac gtcaagcgct cgattgagac catgacaggg
     5821 cttactgttg ttgaggtcaa cgtacatatt catgacgtta tcttcaagac agccgagaag
     5881 atcgaggagt cggaactgag ccacagggtg aaataatgaa tgcagcgatt aacccctgac
     5941 gaatcagcgt caggggttta ctataatctt aaggtgggtg cacgttcagt ggcaaaaatc
     6001 ttggacagac ttctgctgtt tatttatagt ttcagcatag gtattctatc cgtaattgcg
     6061 attcttctct ttaccgaagc ggtacctttt cacattgaca gcagttatga gaagactctg
     6121 ctgaatgtat caattgcggt tgcagctgta ctcttcctgc tcagcatccg gttcttctat
     6181 atttcgatcc ggcgtgacag ggcatcattg ccctcaatcg atcagcggac ggaattcgga
     6241 gatatccaga tttcggtgga gaccattgag aatctgtccc tcaaagctgc atcacgggtt
     6301 agaggcatca aggatgtgaa gacacgaatc aagattaccg agtcgggatt gagcattatt
     6361 attcgcgcgc tagtggacgg ggagagctcc ataccgacac tgactgaaga agttcagagg
     6421 caagtccatg atcacgtaca ggagattacg ggcattccgg tatcttatgt atccgtgtat
     6481 attgctaatc ttgttcagtc gcctacgatc aaaagccggg ttgaataggg gtggatttca
     6541 gggtgctctg gaaacaatta tgggagagtc atagaggacg cttgctgggt ctggctaccg
     6601 ccctgttact ttgtccaatc tatctgtttt tcgggttttg gaacatgctt ttctgcgcgc
     6661 tgctcttgta catcggttat acaatcggta agtataaaga tcttggccag ggctcgttca
     6721 tcccatgggc ggagatacgt gactggctcg gtgcgcgctg gcgtcctttt aaatgattcc
     6781 tgtgatatgc tttctccgaa aaaaactgct gctatacggt gtgccttcgg taaactccgt
     6841 ataattctgc tcattttttt gttgcggaga gcatttcacg ggtttttttc tgtcaatagt
     6901 catgcacact atatggaatg aactacacac aaaatacatc catgatccat acaagggatg
     6961 tccagaggtt aacctcgagg aggaagttaa tgaaaagacg attagctagg gaaatatcgg
     7021 tacaaagcct gtaccaaatg gaaatgaatg atgtcgaagc aaatgaggcc gttacaatgc
     7081 ttctgtcaga agccggcggg gagaacgaga gtgaagttga actcagcgat atggggactc
     7141 cggaattcgt gcttgagctg gtcaacggag tctgggagaa gaaaagcgaa atcgatgccc
     7201 ttctcggtga ttatctgaaa gggtggcaga tcagccggtt gtccagagtg gaccgtcagg
     7261 tcctgcgctt ggcggcttat gagatgatct accgtgatga tgcgcctgcc aaggtggttg
     7321 tgaacgaagc catagagctg gcgaagcact tcggaactgc cgaatccggc aagttcgtta
     7381 atggggttct ggggaagatg attcaggatc tggatcaatt gaaaaacaaa cagtaaaaca
     7441 aacaaacagt taaaaaacaa atcatggaga gggagagaga taatgacagc acaaataatt
     7501 agtgggaaac aggtagctga ggaaattcgc cagggtctgc gtgaggagat ggagagactg
     7561 gcagagacgg gattcaagcc aggtcttgcg gtagtgattg ttggagaaga tcctgcttcc
     7621 caggtctacg tccgtaataa agacaaggct tgccatgacc tgggatatta ttccgaggtt
     7681 cataagttag aggaatccac tacccaggaa gaactgcttg ccctggttaa caagctgaat
     7741 cagcagagca acattcatgg catccttgta cagcttccac tgcctaagca tattgacgag
     7801 aagtccgtaa ttaatgccat tgctgtggaa aaagacgtgg atggattcca tccagtgaat
     7861 gtgggtaatc tggtcattgg agatgacagt ctgcttcctt gtacccctgc aggtgtgatt
     7921 gagctcatta agcgtacggg tcttgatatg gccggcaagc atgccgttgt gatcggacgc
     7981 agtaatattg taggcaagcc agtggctctt ctgctgcagc gggagaacgc tacggttaca
     8041 atgtgtcatt cccgtacagc caacatgaaa gagcttaccc ttcaagcgga tattctggtt
     8101 gttgcggttg gcagagccaa tttcattgat gcgtcctatg tgaagccggg tgcggtagtt
     8161 atcgatgttg gcgtgaaccg tcttgataat ggcaagctcg ctggcgatgt tgattttgac
     8221 agcgtgaagg aagtctccgg gccaatcaca ccggttccag gcggagtagg tccgatgacg
     8281 attacgatgc tgatgaacaa tacgatggtg gcagcaaagc gtcttagcgg tctggaataa
     8341 tccatctttc ataacctgaa ggggggatcc ccgtgaatca aagaatcttc tcgataaagg
     8401 aactgaaccg gtatatccga atgaagctgg aatcggacac gcttctgtcc gaagtgtgga
     8461 tacggggaga aatctcgaac ttcacacacc attcaagcgg tcacatgtac ttcaccttga
     8521 aagataagga cagccggatc aagagcatta tgttcgcttc tcacaaccag cggctgcctt
     8581 ttattccgaa agagggatca agggtgattg caagaggcaa tgtatcggtg tacgaaagag
     8641 acgggcagta ccaattctat gcgacccata tgcagccgga tgggataggc agcttgtatc
     8701 tcgcctatga gcagctgaag aagaagcttg aagatgaagg attgtttgag cagtcccgta
     8761 aaagagctct gccgcgttat ccgaagacga tcggtgtagt tacgtctcca acaggtgccg
     8821 cagtgcggga tatcataatc accttacagc ggcgatatcc gcaggtgccg atcatcctgc
     8881 accccgtgct tgtgcagggc aagcaggcag cgccttcgat tgtgaaggca ctgcgtactc
     8941 tgaacagcat gggagaggcc gatgtaatca tcgtcggccg gggcgggggc tcactcgagg
     9001 agctgtgggc cttcaacgag gagattgtgg cccgggctat ctatgaatcg gcaatccccg
     9061 tcatctcggc cgtgggccat gagactgact ttacgatagc cgatttcgta gccgatcttc
     9121 gcgcagccac gcctacagcc gctgccgagc tggccgtgcc gcatgccgcc gagctgcggg
     9181 cgctgctcgg ccagcgcgag cgggagcttc agcaggggct gaagcaccgt ctggctcgcg
     9241 cccgggagcg gctcgcgcgc ctccagcgct cgccggtgct cgtgcatccg cggcggagcc
     9301 tgctccagca cgccgagcgg ctcgacatgc tgaagcatcg tctcgccagc cgcatgcatg
     9361 cccgcgcgct cttgacgagc gagcggcgcg gccgcctgca tgcgaggctc ctgcggttcc
     9421 atccgcagga gcagctgcag tacgcgaagc ggcgtcagtc ggacgccgca aggcagcttc
     9481 gccaggcaat gctggcggtg ctcaaggata gatccgctca gctgactgca gggattcgtc
     9541 agctcgatgc gctgagccca ctcaaagtca tgggcagggg ctacagcttg gtctatgatg
     9601 aacaaggttc acgcttaatt aaatcgctgg atgaagtcca acctggggat atgctgaaga
     9661 tcaaagtcac cgacggtgaa ctggattgtc aggtatgggg gatgcagcgg gaaggagaca
     9721 gtcatggaac aggagaagga cattaatttt gaagaggcca tgagtcagct cgaagagatc
     9781 gtgtctaagc tggaacatgg agatgtgccg cttgagacgg caatcgatct gtttcagcgg
     9841 gggatgcagc tgtcccagct ctgcggtcag aagctggtac aagtcgaggg aaagatcgag
     9901 atgattgttg aatcagacgg ggagattacg aagaagcctt ttgcagctcc ggtcgaaagt
     9961 ggtgaatcag gtgagtagtc agccttcatt cggctcctat atggaagaaa tcaacaagct
    10021 ggtcaccggt ggacttcaag actttattcc aggggagtgg gttgttccct cctctctcca
    10081 tgaagccatg cgttattcct taatggccgg aggcaaacgc attcgtccac tgctcgtcat
    10141 tgctgcggcg gagtcgctgg gcgggagccg tgaagcggcg ctgcccgtcg cctgcgccgt
    10201 agaaatggta catacatatt cactaatcca tgatgatcta ccggcgatgg ataatgatga
    10261 tttccgcaga ggcaagccta cgaaccacaa ggtgttcggt gaggcgtcag ctattcttgc
    10321 gggtgacggt cttcttaccc atgccttcta cagcattgcc caggcaagcc ggagatacca
    10381 tgttcctgct gaacaaacgt tggccattgt agaagagctg tctttgtacg cagggcccaa
    10441 aggtatggtc ggcgggcagg cagcggatat ggaaggtgag caggggatta caagtctcga
    10501 ccagctgaaa tacatccata tgcacaagac aggcgatctc atcgtcttct cgttgaaggc
    10561 cgggggccgg attgcttccg cttctctgga gcagctcagg gcgttggaga cttttggccg
    10621 aagcattgga ctggcattcc agattcagga cgacatcctg gacctgattg gcaatgagga
    10681 aaagctgggt aagaagacac aaagcgatgt agtgatgaat aaagtgacat acccatattt
    10741 tattggactg gaggagtcga gagctgaggt ggaccggctt accttgcttg ccaaggaggc
    10801 gatcggtggt ggaaccattc cccatccgga ccgtctgctt caaatggccg actttctgct
    10861 taaccgcgat cattagagac aagatttggg acaaaaggag gctgcaggcc ggcacagatt
    10921 attgcagcgc ttacttttgt ggtataatga tcacaattac ctgagggaaa tttgtactac
    10981 tcaccatgac aaatccaaat tgaagaaagc ggggaaatca tgtgctgctt tcacaaattc
    11041 atgaacccaa tgatttaaaa aaatattctg tagacgagct ggacaacatc gcccaggaaa
    11101 tacgcgattt cctgattcag aagctgtccg ctacgggtgg gcatcttgcg ccgaatttag
    11161 gtgtggtaga gctcacgctt gcccttcact attgttataa cagccctgac gacaaattta
    11221 tatttgacgt tggccatcag gcatatgtcc acaagatcct gaccggacga atggagcagt
    11281 tcgatacact tcgcaagtac aaaggcttga gcggatttgt gaagcggaac gaaagtgagc
    11341 atgatgtctg ggaagccggg cacagcagta cttctctgtc ggcggcaatg ggcatggcct
    11401 tggcaaggga tctcaagggc ggaacgaaca aggtagtcgc aattatcgga gatggtgccc
    11461 ttactggggg aatggcattt gaagccatga atcacatcgg tcatgagaag aagaatctta
    11521 tggttatact gaacgataat gagatgtcga tcgctccgaa tgtgggtgcc atgcataatt
    11581 atttgagcaa aatccgatcg gaccggacct atcttcgggc caaggacgag gtggagcttc
    11641 tgcttaagaa gattccggcc attgggggca agctggcgaa gacggcagcc aatctcaagg
    11701 atagcctgaa gtatatgatc atgaacggtg ttctgtttga agagcttggc ttcacctatc
    11761 tgggacccgt tgacggacac gatcttccca agctgatcga agtctttaag caggctgata
    11821 acgtgacagg tcctgtactt gtgcatgttc tgactacgaa aggcaagggg tattcacccg
    11881 ctgaagcgga ttcgcacaag tggcatggca tctcgcctta caagattgaa tcgggcaagg
    11941 tgctgaaagc tgttggaaat ccgatgtata cggaagtgtt cggtcagaca ctgattgagc
    12001 ttgcggagca ggattcccgt atcattgctg taaccccagc tatgccggga ggatcgggtc
    12061 ttcttaaatt cgcggagaag ttccctgatc ggatgatcga tgtgggcatc gctgaacagc
    12121 atgcggcaac catgtgcgca gctctggcta tggaagggat gaagccggtg tacgcggtgt
    12181 attccacttt tatgcagaga gcttacgacc aaatcatcca tgatatttgc cgtcacaatg
    12241 ccaacgtgat gttcgccatt gaccgtgccg ggtttgttgg cgctgacggg gagacgcatc
    12301 agggcgtgta tgatattcct tttttgcgcc atattccgaa tatggttctg atgatgccca
    12361 aggatgagaa cgagctgcgt catatgatga agaccgctct cgagtacaat gatgggccta
    12421 ttgcttatcg ttatcctcga accaacgtgc cgggagtttc tatggatgtg gaattggtac
    12481 ctattccaat cggtacctgg gagaaagtgc gggaaggtga tgggacagcc atcatagccg
    12541 tcgggacaat ggtccaagtt gcagaggagg cggctgagca gctgaagcgt gaaggtatcc
    12601 aagcagcagt gatcaatgca agatttatta agccgcttga tgagactatg ctgcttgagc
    12661 ttgccaagac ccacgccaag atggtggtca ttgaggagtc aaccattgcg ggtggccttg
    12721 gaagtgccat tctggaattc tatgctcagc aaggcatttc cggtcttgac atacgcttga
    12781 tgggagttcc tgacaagttc attgagcatg gcagtattaa ggaacagtgt caagaagtgg
    12841 gtctcacaac cgaggccttg atagaacaag ttcaaaagct gcggaatgat caccatttcg
    12901 catttggtaa gaagacgctg ccttcgtagg cagcttcttt aatgaagtcg ggactacagg
    12961 agatgaacat ggctggttct aaggaacgga tagatgtcct gcttgtggag caaggatttt
    13021 ttgagagcag agagaaggcg aaggcagcta ttatggccgg tctggtgtat ggggatacgg
    13081 aacggattga gaaggccgga accaagattc cgcgtgacac ccagcttaac gtgaaagggg
    13141 ctatacaccc ctacgtgagc cgtggaggtc ttaagcttgc caaggcgata aatacttttg
    13201 gattagatat gagcggacgg gttatgctcg atatcggcgc gtcaacgggt gggttcaccg
    13261 actgtgcgct tcagaacgga gcgtcttatg tctacgcgat agatgtaggt tacaatcagc
    13321 tggattggtc gctgcgtaat gacgagaggg tcaatgtcaa ggaacgcatg aactttaggt
    13381 atatgacccc ggaagatctg gatggcccgg tgcctgattt cgcgagtatt gatgtttctt
    13441 ttatttccct gaaattaatt ctgcctccgc ttaagagtct gctgaagcgg ccggctgatg
    13501 tcgctgcgct gattaagcct caatttgaag cgggcaggga caaggtgcca aagactggag
    13561 ttgtccgtga tgccaaggta catcaggagg tgatggaaca agtgcttact tttgccgtag
    13621 aggaaggctt tggtattaag ggattaacct tctcgcctat caccggaggg gaaggtaata
    13681 tcgaatttct ggtgcacctt cggcttgatc cggatgagca gaatgaggga gattctaagt
    13741 tgaatatacc ggagcttgcc cgcaacgttg tagaagaagc ttcgggtacc tttaaccctc
    13801 aacataaatg agccgctgcc tgcagcggtt ttttttcggg attgaaactc ttttaataaa
    13861 tcttgtataa tgagaacaag tgtttctttt ttggttggtc cgtatattta tgtattagaa
    13921 aaaggatgag gtccttccct tgtcgaatta ccctttgagg tgatggaata ggtatgcagg
    13981 cagatggatt tttaatagtt gttgtcgttg ccattctgtt gtatctgatc taccggagtg
    14041 ttcagtcctg gctgcgtagg ccggcattgt taagacgcgg acttcacttc gatctgaatg
    14101 aggacattcc tggtcaccct gctgtggaat tgctgaagga gcacgggtac gaggtgatca
    14161 gcggcaagct tcgggtacct cttaccttca tggttaacca tacgaagctg cacagccggc
    14221 tgtttatcga ttatgtagct acccgggaag atgaactgta tttagttaga ttagctcgtg
    14281 caagacagcc actagaatgg actggcagcg gagtccgcca ggaactgctc ccatttcttt
    14341 tgttatatcc ggattgttca ggtttattat atatcgatgc cgagcatagt gagattaaag
    14401 tcatcgtact ggattctgat gatgaataag ccgaatatta ggcatttacg gaggaatgta
    14461 tgaaaggcca aagacatatc aagatacgtg aaattattac cggacaggaa attgaaaccc
    14521 aggatgaact cgtagaagct ctgcgtgagg cgggttatca ggtgactcag gccacggtat
    14581 ccagggatat aaaggagctt ctgctcatta aagttccaat ggacgatggc aggtacaagt
    14641 attcacttcc ggtcgatcaa agggctaatc cggtacagaa gctgaggcgc tatctggttg
    14701 acagctttgt acatattgat tatacaggga acctggttgt gatgaagtgt ctgccgggaa
    14761 ccgcgaattc cgtagctgta ctgattgata atatggagtg gccagagata ctgggcacaa
    14821 tctgcggaga cgatacgata ttgatcatct gccgaacgga agagtacagc aagtccatta
    14881 ttaatcaaat tatgagtttt attccttaat aggcggacgg aggtgcgctc atgttagttc
    14941 acttgtcaat tagaaacctg gccgtagttg aatcggttga tgttacattc catcgaggct
    15001 ttcatgttct tactggggag acgggtgccg gcaaatccat tattatagat gctcttggct
    15061 tcattgcggg aggacggggg tcagccgatc tgatccggta cggttgcgac aaggcagaga
    15121 ttgaagcctc ctttgatctg cggggcaatc atcctgcatg gagtacgctc gaaggcttgg
    15181 gcatacatgc cgatccgtca gaggagctta tcattcgcag ggagatcagt gcgcagggta
    15241 agagtatctc caggatcaac ggtcaaatgg tgaatttgag catgctcaga gagattggcg
    15301 accaactgat caacattcat ggtcagcatg agcaccagac gctgcttcgt ccagagcggc
    15361 atctccattt gctggatgca tttggatccg acattctggc cccgctaaag gcaagttatc
    15421 aagcgaccta ttccgcgttt gttaaggtgg agaaggaatg gaatgagctc cagaaatcca
    15481 gtcagcagac attccagatg ctggatatgt accgttacca gattgaggag atcgcagccg
    15541 ccaaactaaa agccggagaa gatgaattac ttgcggaaga aaaggtcaag ctatcccata
    15601 gtgagaaaat gatggattcc atctcgggtg cctatgagct gctcaacggt tcacatgggc
    15661 ttgaagctgt agccaaagcc atatccaggt tcgaggatat tgccggttat gattccaagg
    15721 gaatcgggcc gatcctggaa cagctgcaat ccgcttatta tcagctggaa gatgcctcat
    15781 ttgctctgcg gaattaccgg gatggcattg aggttaactc tggccggctg gacgaggtac
    15841 aagaaaggct ggatttcatt tcgaccttga agcgcaaata tggggacagt attgagcgaa
    15901 tccttgccta ttatgatcag atcacacagg agaccgacac gctggagaac aaggatgaaa
    15961 ttctggagag actgagtgcc cgcagggaga agctgcttac ccagcttctt gaagaagggg
    16021 aggcattaag tcaggcacgg cagcggtgcg ccgacgactt ggccattcag atcgaagctg
    16081 agctgaagga tctgcagatg ggccgtacct ccctcaaagt taaatttggc cggcttgagg
    16141 atccatcggg agtggagtgg agaggtcagc gtatccgcgt aagccggcag ggcctggata
    16201 cggccgagtt cttgatctca ccaaatccag gcgagccgct aaggccgctt ggcaagattg
    16261 cttctggtgg tgagctgtcc aggatgatgc ttgccttgaa gagcattttt gcaagacatg
    16321 atgaagtgcc ggttctaata tttgacgaag tggatacggg agttagcggc cgggcagccc
    16381 agtccatagc agagaagctg tacaagctgt cagcaacctg tcaggtgttc tcaatcacac
    16441 accttcctca ggtagcctgt atggctgaca atcagtatct tattgagaag acggttcatg
    16501 acggccgtac catgactcaa gtggaggctt tgacggagac aggccgggtg aaggagcttg
    16561 cccgtatgct cggcggggtt gaaattacgg agaagaccct gcatcatgcc caggaaatgc
    16621 tcgggttggc aagggatcag aaggctgagg ttacttgccg gagtaatgat tgacagtaat
    16681 aaatggcctg ctcgggggta tcttataggt acgcaattgg cgaccacctt ttcgtcaagc
    16741 gatagaagct aagggagcgt gacagccatt gaacccgaac ctcaggaaga gaatgctcgg
    16801 ccttttattt acttttttct tttgtttctt aggttcggca gcagcaggag aggtcagcaa
    16861 tccactcatg ccgaacgagc ttagattagt cgagggcgag cttgcccgta tagaatcagc
    16921 ccttccggtt ctggcacaag tcagtgtaga ccggccggat gtggtacagc ttggcggtga
    16981 tgctaagtcg tccgcgggtg atgtttcttt tggtaaagga aagccgctgc tgcttagttc
    17041 ccaatccgca ggagaggctc atctccgtat gaaattattc ggtcaaattc ctcttaagac
    17101 agtcaaagtc aatgttattc ccgatctcaa ggttatcccg ggtggacaga ccattggtgt
    17161 taagctgaaa tcgtctggta ttttggttgt aggacaccat ttggtcagca tgtccggtaa
    17221 ctccaagcaa tccccaggag aaaaggcagg acttcagctc ggcgaccgca ttacgcacat
    17281 gaatggcatc gagctcaagg atgtgaagga tgttgcctca attgttgaac aggcaggcca
    17341 gcagaagcag ccgcttgaag tgacttataa gcgcggagag cacgtctaca gaaccacatt
    17401 gtctcctgtc tttgacgagc aggacaagac gtggcgtctg gggctttata ttcgcgattc
    17461 ggctgcgggc gtgggtaccc ttacttttta tgctccagag caaggggtct atggggcttt
    17521 gggtcatgta atcactgata tgaataccca gacacctatt gtggttggca gtggccaaat
    17581 tgttgaatca agcgttactt caatctccaa gagcgagaac ggagaacccg gggagaaaag
    17641 ggcgcatttt atcaaagagg gccgtgtcct aggaaatatt gagcagaata ccgactttgg
    17701 catattcggc aagatgtcca cgaatccgga gcatagcctc tatggtgatc ctattcctgt
    17761 cggttttgct gagcatgtga aagaaggccc tgccgaaatc ctgactgtcg taagcggaca
    17821 aaaagtggaa agatacagca tcgaaatcgt ccatgtctca tctcaaaatg caccacaaac
    17881 caaagggatg gtcattcgga ttacggatcc aagattagtg aacaagaccg gcggaattgt
    17941 ccagggaatg agcgggagcc caatcattca gaacggcaag ttgattggtg cagtaaccca
    18001 tgtctttgtg aatgatccca aatcgggata tggctgcttt attgaatgga tgctgcagga
    18061 tgctggtgtc atgatcaaca attcagggca agcgaaaaat cttaaggcga gctaaccgcc
    18121 ttaagatttt tttgtcgaaa aagaaaaatt gacgtcaagt attgtaataa atattttatt
    18181 ataatatagg ctttaaaaaa aataaagaaa aataattttc gacgaaggga ttcagatctt
    18241 tatgtcgaat ccatatatta ggacatgaaa agataagcga cacaaataca gaatttctaa
    18301 ggaggacatg gaaattgcaa aacattgagg tattgttggc tgacgataat cgggaattta
    18361 cgaatttact ggcggagtac atttcaggac aggaagatat gaccatctcg ggtattgcat
    18421 acaacggaga agaagctctt cagatgatcg agaacggctc caagattcct gatgttctga
    18481 ttcttgatat tattatgcct catctggacg gattgggcgt acttgaacgc cttcgtgata
    18541 tgaatctgtc tccgcagcct aaggtaatca tgctaacggc atttggacaa gagaatatta
    18601 cacaaagagc ggtgcagctc ggggcttcgt actacatcct caagcctttt gatatggaag
    18661 tgcttgctca acgaattcgt cagctggtcg ggattccatc gcaaagtcta ggcagtcaaa
    18721 gttcaacttc atcgtcctcc ttgttcaaat ccaatgtggt tcctatggct aaagggaaga
    18781 acctggatgc gaatattacc tcgatcatac atgaaattgg cgtacctgcg catattaaag
    18841 gatatcagta tttgcgtgaa gccatcacta tggtgtacaa caatatagaa atcttgggag
    18901 caatcaccaa gaccctgtat ccggctattg cggagaaatt taagacaacc ccttcacggg
    18961 tggagcgcgc aatccgccat gctattgaag tagcctggac ccgcgggaac attgattcca
    19021 tcagtcacct gttcggttat accatcaaca tcagcaaatc aaagccgacc aacagtgaat
    19081 tcatcgccat ggtggcagat aagctgagaa ttgagcataa ggttagctga aagggtaagg
    19141 ggctgtgagt acaataatat acagaagctc atgcagcatc tgtagaagct aaagtcattt
    19201 ctgaagggaa gcagcatgct aaccttggaa gtggctttgt tttttataga aaattcctat
    19261 aatcggtaca aaaaagttga ttacctgcac atacctaatc atggtaaagt aatattatcc
    19321 catgttaacg ggtaggtttt attggagatt atgatcactt cactgttaag gaggaggatg
    19381 gatatgagca gcaggcaaga aagattaata atccgtgatg ctgtgcctga ggatcgggca
    19441 tcgatcgaga aattgatggt agaagcttac ggacaatatg agcagagcat gccggaggaa
    19501 cggtggaagc catatatcaa gtcaattcgt gaatctgtct atacagaagg cccggcagcg
    19561 cgcattgtag ccgagctaaa tggggaaatt gtgggcagtc tgcttgtttt cttgtcctcg
    19621 gaagcggcgt atggccgtcc tgatctcaag atagaatctc cgatcattcg tctgctcgca
    19681 acttctccga aggcaagggg gagagggatt gccacccaat tgattagtga gactgtacgc
    19741 agagctaagc tgtggggcgc tgatacaatt catctgcata cgtctgatgt catggctccc
    19801 gccataagat tatatgagtt tctaggcttt gagcgtgcca gggagaagga aatgcagaat
    19861 ggagacatac ttgtgaagtg ctatcggctt cagctgcagc ctattgaagc ttaagaggag
    19921 tgggttgtta cccattccat ctagcttagt ctttggacac ttatgtatag gggtgcacag
    19981 gtgtggatat atggatatac aaaaggagcc tctgacaatc agaagctcct tttgtgcagg
    20041 tatttacatt taaggtctat tactatactt cgaatccatg ggaagcaatc acgttctggt
    20101 accaataata gctgtctttc ggcgtccgtg tataggtctt gaagtcgaca tgcacgatgc
    20161 cgaatggctt ggtgtagccg aatgcccatt cgaagttatc cataagggac cacagcatgt
    20221 atcctttaac gttgattcct gattcaatgg ctcgtgagag ctggaaaaga tgcttttgca
    20281 ggtaagcgat acgctttgga tcatgctgct tgccgtcttc acttgcttca gactcgtaat
    20341 aagcgccatt ctcagtgata tagatcggaa tagagccgta ttcacggtct acccattgaa
    20401 gaacattcaa gaagccctga gggtagatgt tccaatcgaa atcggttgta tcgaacccgc
    20461 cggataccgg ctcgaattcc agaattcctg cttcaggatc atgcctgccg acaccaccgg
    20521 tataatagtt aatcccaatg aaatcaatgg gctggctaat gatctccaaa tctccaggca
    20581 gaaccggagg ttcatatcct ttggatttgt accagttcag agctctttgt gggtagattc
    20641 ccttgaatac cggatcgaag aaccagttat tgaagtactc aagacggcgc tctgcggctt
    20701 caacatcctg ttcttgctgg ctgaagggct caaaccattc cgtgttcgga gcaaaaccaa
    20761 tctctccttt aatgcctaat tgtctaaagg acttcacggt ctccccatgg gcaacgagga
    20821 tatgatgggc gacgttcaga gcaagctgga aatctttgtt cccgggggca tggtcg
//
